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7. Modifiers of the Risk of Diabetes for Long-Term Outcomes After Coronary Revascularization: CREDO-Kyoto PCI/CABG Registry

Author

Kimura, Takeshi, Shiomi, Hiroki, Matsuda, Mitsuo, Takeuchi, Yuzo, Mitsuoka, Hirokazu, Uegaito, Takashi, Nakagawa, Yoshihisa, Tamura, Toshihiro, Konishi, Takashi, Ootani, Seiji, Fujiwara, Hisayoshi, Takatsu, Yoshiki, Sato, Yukihito, Taniguchi, Ryoji, Kataoka, Kazuaki, Inoko, Moriaki, Nohara, Ryuji, Nakano, Kimisato, Miyamoto, Syoichi, Kunihiko, Nagai, Murakami, Tomoyuki, Takeda, Teruki, Ishida, Katsuya, Nobuyoshi, Masakiyo, Yamaji, Kyohei, Yasumoto, Hitoshi, Iwabuchi, Masashi, Ando, Kenji, Domei, Takenori, Kato, Masayuki, Tatami, Ryozo, Shirotani, Manabu, Hattori, Ryuichi, Kita, Toru, Furukawa, Yutaka, Ehara, Natsuhiko, Kihara, Yasuki, Eizawa, Hiroshi, Kato, Hiroshi, Ishii, Katsuhisa, Aoyama, Takeshi, Sakurai, Takahiro, Kawanami, Masaki, Suyama, Tamaki, Tada, Eiji, Tanaka, Masaru, Inada, Tsukasa, Uzui, Hiroyasu, Nakano, Akira, Lee, Jong-Dae, Onodera, Tomoya, Takizawa, Akinori, Ryuzo, Nawada, Shinoda, Eiji, Takahashi, Masaaki, Yamada, Miho, Horie, Minoru, Yamamoto, Takashi, Takashima, Hiroyuki, Sakai, Hiroshi, Tamura, Takashi, Toyofuku, Mamoru, Kotoura, Hajime, Miura, Akira, Takahashi, Mamoru, Matoba, Yoshiki, Takumi, Takuro, Tei, Chuwa, Hamasaki, Shuichi, Doi, Osamu, Kambara, Hirofumi, Kaburagi, Satoshi, Sakamoto, Hiroki, Tada, Tomohisa, Mitsudo, Kazuaki, Kadota, Kazushige, Tada, Takeshi, Miki, Shinji, Mizoguchi, Tetsu, Akira, Yoshida, Kaneda, Kazuhisa, Ogawa, Hisao, Sugamura, Koichi, Sugiyama, Seigo, Doyama, Kiyoshi, Araki, Makoto, Suwa, Satoru, Sakata, Ryuzo, Ikeda, Tadashi, Marui, Akira, Minatoya, Kenji, Yamazaki, Kazuhiro, Onoe, Masahiko, Ogawa, Tatsuya, Yamanaka, Kazuo, Iwakura, Atsushi, Ohno, Nobuhisa, Fujiwara, Keiichi, Hanyu, Michiya, Soga, Kinji, Matsushita, Tsutomu, Nishiwaki, Noboru, Yoshida, Yuichi, Tamura, Nobushige, Okada, Yukikatsu, Nasu, Michihiro, Koyama, Tadaaki, Nakayama, Shogo, Tanaka, Kuniyoshi, Koshiji, Takaaki, Morioka, Koichi, Shimamoto, Mitsuomi, Yamazaki, Fumio, Terai, Yasuhiko, Nishizawa, Junichiro, Aota, Masaki, Kanemitsu, Naoki, Hara, Hiroyuki, Tabata, Takafumi, Imoto, Yutaka, Yamamoto, Hiroyuki, Matsuda, Katsuhiko, Nara, Masafumi, Tsuneyoshi, Hiroshi, Komiya, Tatsuhiko, Nakajima, Hiroyuki, Esaki, Jiro, Kawasuji, Michio, Moriyama, Syuji, Tambara, Keiichi, Arimura, Sakiko, Fujino, Yumika, Hanazawa, Miya, Hibi, Chikako, Kato, Risa, Kinoshita, Yui, Kitagawa, Kumiko, Kitamura, Masayo, Kuwahara, Takahiro, Sachiko, Maeda, Miki, Izumi, Minematsu, Saeko, Nishida, Satoko, Okamoto, Naoko, Saeki, Asuka, Sasae, Hitomi, Sato, Yuki, Takahashi, Asuka, Takinami, Emi, Tezuka, Saori, Tsuda, Marina, Tsumori, Miyuki, Uchida, Yuriko, Yamamoto, Yuko, Yamauchi, Misato, Yamazaki, Itsuki, Yoshimoto, Mai, Abe, Mitsuru, Fuki, Masayuki, Hayano, Mamoru, Kato, Eri, Kato, Yoshihiro, Matsumura-Nakano, Yukiko, Nakajima, Tetsu, Nakatsuma, Kenji, Natsuaki, Masahiro, Takeji, Yasuaki, Tazaki, Junichi, Tokushige, Akihiro, Watanabe, Hiroki, Yaku, Hidenori, Yamamoto, Erika, Yamamoto, Ko, Yamashita, Yugo, Yoshikawa, Yusuke, Morimoto, Takeshi, Kato, Eri T., Imada, Kazuaki, Nishikawa, Ryusuke, Mabuchi, Hiroshi, and Soga, Yoshiharu

Published
2022
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8. Comparison of open and hybrid endovascular repair for aortic arch: a multi-centre study of 1052 adult patients.

Author

Sakamoto, Kazuhisa, Shimamoto, Takeshi, Esaki, Jiro, Komiya, Tatsuhiko, Ohno, Nobuhisa, Nakayama, Shogo, Paku, Masaki, Hidaka, Yu, Morita, Satoshi, Marui, Akira, Minatoya, Kenji, and Investigators, Advance-Kyoto

Abstract

OBJECTIVES We aimed to evaluate early and late outcomes by comparing open total arch repair and endovascular arch repair using proximal landing zone analysis in a multicentre cohort. METHODS From 2008 to 2019, patients treated surgically for aortic arch disease at 6 centres were included, excluding cases with type A aortic dissection, additional aortic root replacement and extensive aortic aneurysm. In all patients and populations with proximal landing zones 0/1 (N  = 144) and 2 (N  = 187), early and late outcomes were compared using propensity score matching. RESULTS A total of 1052 patients, including 331 (31%) and 721 (69%) patients undergoing endovascular arch repair and open total arch repair, respectively, were enrolled. After propensity score match (endovascular arch repair, 295; open total arch repair, 566), no significant difference was observed in in-hospital mortality rate (endovascular arch repair, 6.8%; open total arch repair, 6.2%; P  = 0.716). Open total arch repair was associated with a lower risk of all-cause death [log-rank test; P  = 0.010, hazard ratio (HR) 1.41 (95% confidence interval 1.17–1.71)]. The incidence of aorta-related death was higher in endovascular arch repair [Gray's test; P  = 0.030, HR; 1.44 (95% confidence interval 1.20–1.73)]. When compared to endovascular arch repair with proximal landing zone 0/1, open total arch repair was associated with lower risks of all-cause death [log-rank test; P  < 0.001, HR 2.04 (95% confidence interval 1.43–2.90)] and aorta-related death [Gray's test; P  = 0.002, HR 1.67 (95% confidence interval; 1.25–2.24)]. There was no difference in the risk of all-cause death [log-rank test; P  = 0.961, HR 0.99 (95% confidence interval 0.67–1.46)] and aorta-related death [Gray's test; P  = 0.55, HR 1.31 (95% confidence interval 1.03–1.67)] between endovascular arch repair with proximal landing zone 2 and open total arch repair. CONCLUSIONS Open total arch repair was considered the 1st choice based on early and late results; however, endovascular arch repair may be a useful option if the proximal landing zone is limited to zone 2. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Comparison of Outcomes of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting Among Patients With Three-Vessel Coronary Artery Disease in the New-Generation Drug-Eluting Stents Era (From CREDO-Kyoto PCI/CABG Registry Cohort-3)

Author

Matsumura-Nakano, Yukiko, Shiomi, Hiroki, Morimoto, Takeshi, Yamaji, Kyohei, Ehara, Natsuhiko, Sakamoto, Hiroki, Takeji, Yasuaki, Yoshikawa, Yusuke, Yamamoto, Ko, Imada, Kazuaki, Tada, Takeshi, Taniguchi, Ryoji, Nishikawa, Ryusuke, Tada, Tomohisa, Uegaito, Takashi, Ogawa, Tatsuya, Yamada, Miho, Takeda, Teruki, Eizawa, Hiroshi, Tamura, Nobushige, Tambara, Keiichi, Suwa, Satoru, Shirotani, Manabu, Tamura, Toshihiro, Inoko, Moriaki, Nishizawa, Junichiro, Natsuaki, Masahiro, Sakai, Hiroshi, Yamamoto, Takashi, Kanemitsu, Naoki, Ohno, Nobuhisa, Ishii, Katsuhisa, Marui, Akira, Tsuneyoshi, Hiroshi, Terai, Yasuhiko, Nakayama, Shogo, Yamazaki, Kazuhiro, Takahashi, Mamoru, Tamura, Takashi, Esaki, Jiro, Miki, Shinji, Onodera, Tomoya, Mabuchi, Hiroshi, Furukawa, Yutaka, Tanaka, Masaru, Komiya, Tatsuhiko, Soga, Yoshiharu, Hanyu, Michiya, Ando, Kenji, Kadota, Kazushige, Minatoya, Kenji, Nakagawa, Yoshihisa, and Kimura, Takeshi

Published
2021
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14. Fluttering cord-like thrombus in the aortic arch

Author

Kuroda, Yuki, primary, Marui, Akira, additional, Arai, Yoshio, additional, Nagasawa, Atsushi, additional, Tsumaru, Shinichi, additional, Arakaki, Ryoko, additional, Iida, Jun, additional, Wada, Yuki, additional, Tamai, Yumeka, additional, Fukushima, Takashi, additional, and Soga, Yoshiharu, additional

Published
2024
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16. Identification and verification of communicating accessory bile duct associated with a biliary circuit by modified and dynamic intraoperative cholangiography during laparoscopic cholecystectomy

Author

Chikamori, Fumio, primary, Yamada, Ryo, additional, Ueta, Koji, additional, Uemura, Sunao, additional, Onishi, Kazuhisa, additional, Yoshida, Mitsuteru, additional, Tanida, Nobuyuki, additional, Yamai, Hiromichi, additional, Matsuoka, Hisashi, additional, Hokimoto, Norihiro, additional, Iwabu, Jun, additional, Mizobuchi, Kai, additional, Marui, Akira, additional, and Sharma, Niranjan, additional

Published
2023
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18. Robot‐assisted total remnant gastrectomy for interposed jejunal pouch dysfunction 25 years after proximal gastrectomy for gastric cancer: A case report

Author

Uemura, Sunao, primary, Yamai, Hiromichi, additional, Onishi, Kazuhisa, additional, Chikamori, Fumio, additional, Yoshida, Mitsuteru, additional, Hokimoto, Norihiro, additional, Matsuoka, Hisashi, additional, Iwabu, Jun, additional, Ueta, Koji, additional, Yamada, Ryo, additional, Mizobuchi, Kai, additional, Marui, Akira, additional, and Tanida, Nobuyuki, additional

Published
2023
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19. Navigation by modified and dynamic intraoperative cholangiography during laparoscopic subtotal cholecystectomy for difficult gallbladder

Author

Chikamori, Fumio, primary, Yamada, Ryo, additional, Ueta, Koji, additional, Onishi, Kazuhisa, additional, Yoshida, Mitsuteru, additional, Tanida, Nobuyuki, additional, Yamai, Hiromichi, additional, Matsuoka, Hisashi, additional, Hokimoto, Norihiro, additional, Uemura, Sunao, additional, Iwabu, Jun, additional, Mizobuchi, Kai, additional, Marui, Akira, additional, and Sharma, Niranjan, additional

Published
2023
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20. Incidence, clinicopathological characteristics, and therapeutic strategy for gastric cancer patients with metastasis to the central nervous system.

Author

Namikawa, Tsutomu, Marui, Akira, Yokota, Keiichiro, Kawanishi, Yasuhiro, Munekage, Masaya, Uemura, Sunao, Maeda, Hiromichi, Kitagawa, Hiroyuki, Kobayashi, Michiya, and Hanazaki, Kazuhiro

Subjects
*STOMACH cancer, *CENTRAL nervous system, *METASTASIS, *EPIDERMAL growth factor receptors, *CANCER patients
Abstract

Aim: This study aimed to analyze the clinicopathologic features and treatment outcomes of central nervous system (CNS) metastasis from gastric cancer. Methods: A total of 419 patients diagnosed with unresectable advanced or recurrent gastric cancer at Kochi Medical School between January 2007 and December 2021 were evaluated. Data of patients were reviewed, and clinicopathological information and survival outcomes of those with CNS metastases were compared to patients without CNS metastases. Results: In total, 12/419 (2.9%) patients (median age: 66.5 years [range, 41–82 years]) were diagnosed with CNS metastasis from gastric cancer. Eleven had diffuse‐type gastric cancer which was significantly more common than in those without CNS metastasis (91% vs. 61%, p =.034). Human epidermal growth factor receptor 2 status was positive in one of the 12 patients. The median survival time was significantly lower for patients with CNS metastasis than for those without CNS metastasis (1.8 months vs. 11.4 months, p <.001). The median survival time for patients who underwent surgical resection, radiation, or chemotherapy for CNS metastasis was significantly higher than those who received only best supportive care (3.5 months vs..6 months; p =.007). Conclusions: CNS metastasis was found in 2.9% (12/419) of patients with unresectable advanced or recurrent gastric cancer. Diffuse‐type histology was a risk factor for CNS metastasis. Multidisciplinary treatment, including surgical resection, radiation treatment, or chemotherapy, for CNS metastasis from gastric cancer may benefit selected patients. [ABSTRACT FROM AUTHOR]

Published
2023
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26. Safety and efficacy of sustained release of basic fibroblast growth factor using gelatin hydrogel in patients with critical limb ischemia

Author

Kumagai, Motoyuki, Marui, Akira, Tabata, Yasuhiko, Takeda, Takahide, Yamamoto, Masaya, Yonezawa, Atsushi, Tanaka, Shiro, Yanagi, Shigeki, Ito-Ihara, Toshiko, Ikeda, Takafumi, Murayama, Toshinori, Teramukai, Satoshi, Katsura, Toshiya, Matsubara, Kazuo, Kawakami, Koji, Yokode, Masayuki, Shimizu, Akira, and Sakata, Ryuzo

Published
2016
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27. Basic Fibroblast Growth Factor and Angiogenesis

Author

Marui, Akira, Doi, Kazuhiko, Tambara, Keiichi, Sakakibara, Yutaka, Ueyama, Koji, Iwakura, Atsushi, Yamamoto, Masaya, Ikeda, Tadashi, Tabata, Yasuhiko, Komeda, Masashi, Mori, Hidezo, editor, and Matsuda, Hikaru, editor

Published
2005
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29. Incidence, clinicopathological characteristics, and therapeutic strategy for gastric cancer patients with metastasis to the central nervous system

Author

Namikawa, Tsutomu, primary, Marui, Akira, additional, Yokota, Keiichiro, additional, Kawanishi, Yasuhiro, additional, Munekage, Masaya, additional, Uemura, Sunao, additional, Maeda, Hiromichi, additional, Kitagawa, Hiroyuki, additional, Kobayashi, Michiya, additional, and Hanazaki, Kazuhiro, additional

Published
2022
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30. Percutaneous coronary intervention using new-generation drug-eluting stents versus coronary arterial bypass grafting in stable patients with multi-vessel coronary artery disease: From the CREDO-Kyoto PCI/CABG registry Cohort-3

Author

50728037, 30837670, 10844920, 50860582, Watanabe, Hiroki, Yamamoto, Ko, Shiomi, Hiroki, Morimoto, Takeshi, Kato, Eri, Matsumura, Yukiko, Nakatsuma, Kenji, Takeji, Yasuaki, Yaku, Hidenori, Yamamoto, Erika, Yamashita, Yugo, Yoshikawa, Yusuke, Fuki, Masayuki, Yamaji, Kyohei, Ehara, Natsuhiko, Sakamoto, Hiroki, Imada, Kazuaki, Tada, Takeshi, Taniguchi, Ryoji, Nishikawa, Ryusuke, Tada, Tomohisa, Uegaito, Takashi, Ogawa, Tatsuya, Yamada, Miho, Takeda, Teruki, Eizawa, Hiroshi, Tamura, Nobushige, Tambara, Keiichi, Suwa, Satoru, Shirotani, Manabu, Tamura, Toshihiro, Inoko, Moriaki, Nishizawa, Junichiro, Natsuaki, Masahiro, Sakai, Hiroshi, Yamamoto, Takashi, Kanemitsu, Naoki, Ohno, Nobuhisa, Ishii, Katsuhisa, Marui, Akira, Tsuneyoshi, Hiroshi, Terai, Yasuhiko, Nakayama, Shogo, Yamazaki, Kazuhiro, Takahashi, Mamoru, Tamura, Takashi, Esaki, Jiro, Miki, Shinji, Onodera, Tomoya, Mabuchi, Hiroshi, Furukawa, Yutaka, Tanaka, Masaru, Komiya, Tatsuhiko, Soga, Yoshiharu, Hanyu, Michiya, Ando, Kenji, Kadota, Kazushige, Minatoya, Kenji, Nakagawa, Yoshihisa, Kimura, Takeshi, 50728037, 30837670, 10844920, 50860582, Watanabe, Hiroki, Yamamoto, Ko, Shiomi, Hiroki, Morimoto, Takeshi, Kato, Eri, Matsumura, Yukiko, Nakatsuma, Kenji, Takeji, Yasuaki, Yaku, Hidenori, Yamamoto, Erika, Yamashita, Yugo, Yoshikawa, Yusuke, Fuki, Masayuki, Yamaji, Kyohei, Ehara, Natsuhiko, Sakamoto, Hiroki, Imada, Kazuaki, Tada, Takeshi, Taniguchi, Ryoji, Nishikawa, Ryusuke, Tada, Tomohisa, Uegaito, Takashi, Ogawa, Tatsuya, Yamada, Miho, Takeda, Teruki, Eizawa, Hiroshi, Tamura, Nobushige, Tambara, Keiichi, Suwa, Satoru, Shirotani, Manabu, Tamura, Toshihiro, Inoko, Moriaki, Nishizawa, Junichiro, Natsuaki, Masahiro, Sakai, Hiroshi, Yamamoto, Takashi, Kanemitsu, Naoki, Ohno, Nobuhisa, Ishii, Katsuhisa, Marui, Akira, Tsuneyoshi, Hiroshi, Terai, Yasuhiko, Nakayama, Shogo, Yamazaki, Kazuhiro, Takahashi, Mamoru, Tamura, Takashi, Esaki, Jiro, Miki, Shinji, Onodera, Tomoya, Mabuchi, Hiroshi, Furukawa, Yutaka, Tanaka, Masaru, Komiya, Tatsuhiko, Soga, Yoshiharu, Hanyu, Michiya, Ando, Kenji, Kadota, Kazushige, Minatoya, Kenji, Nakagawa, Yoshihisa, and Kimura, Takeshi

Abstract

AIMS: There is a scarcity of studies comparing percutaneous coronary intervention (PCI) using new-generation drug-eluting stents (DES) with coronary artery bypass grafting (CABG) in patients with multi-vessel coronary artery disease. METHODS AND RESULTS: The CREDO-Kyoto PCI/CABG registry Cohort-3 enrolled 14927 consecutive patients who underwent first coronary revascularization with PCI or isolated CABG between January 2011 and December 2013. The current study population consisted of 2464 patients who underwent multi-vessel coronary revascularization including revascularization of left anterior descending coronary artery (LAD) either with PCI using new-generation DES (N = 1565), or with CABG (N = 899). Patients in the PCI group were older and more often had severe frailty, but had less complex coronary anatomy, and less complete revascularization than those in the CABG group. Cumulative 5-year incidence of a composite of all-cause death, myocardial infarction or stroke was not significantly different between the 2 groups (25.0% versus 21.5%, P = 0.15). However, after adjusting confounders, the excess risk of PCI relative to CABG turned to be significant for the composite endpoint (HR 1.27, 95%CI 1.04-1.55, P = 0.02). PCI as compared with CABG was associated with comparable adjusted risk for all-cause death (HR 1.22, 95%CI 0.96-1.55, P = 0.11), and stroke (HR 1.17, 95%CI 0.79-1.73, P = 0.44), but with excess adjusted risk for myocardial infarction (HR 1.58, 95%CI 1.05-2.39, P = 0.03), and any coronary revascularization (HR 2.66, 95%CI 2.06-3.43, P<0.0001). CONCLUSIONS: In this observational study, PCI with new-generation DES as compared with CABG was associated with excess long-term risk for major cardiovascular events in patients who underwent multi-vessel coronary revascularization including LAD.

Published
2022

33. Modifiers of the Risk of Diabetes for Long-Term Outcomes After Coronary Revascularization

Author

Yamaji, Kyohei, primary, Shiomi, Hiroki, additional, Morimoto, Takeshi, additional, Matsumura-Nakano, Yukiko, additional, Ehara, Natsuhiko, additional, Sakamoto, Hiroki, additional, Takeji, Yasuaki, additional, Yoshikawa, Yusuke, additional, Yamamoto, Ko, additional, Kato, Eri T., additional, Imada, Kazuaki, additional, Tada, Takeshi, additional, Taniguchi, Ryoji, additional, Nishikawa, Ryusuke, additional, Tada, Tomohisa, additional, Uegaito, Takashi, additional, Ogawa, Tatsuya, additional, Yamada, Miho, additional, Takeda, Teruki, additional, Eizawa, Hiroshi, additional, Tamura, Nobushige, additional, Tambara, Keiichi, additional, Suwa, Satoru, additional, Shirotani, Manabu, additional, Tamura, Toshihiro, additional, Inoko, Moriaki, additional, Nishizawa, Junichiro, additional, Natsuaki, Masahiro, additional, Sakai, Hiroshi, additional, Yamamoto, Takashi, additional, Kanemitsu, Naoki, additional, Ohno, Nobuhisa, additional, Ishii, Katsuhisa, additional, Marui, Akira, additional, Tsuneyoshi, Hiroshi, additional, Terai, Yasuhiko, additional, Nakayama, Shogo, additional, Yamazaki, Kazuhiro, additional, Takahashi, Mamoru, additional, Tamura, Takashi, additional, Esaki, Jiro, additional, Miki, Shinji, additional, Onodera, Tomoya, additional, Mabuchi, Hiroshi, additional, Furukawa, Yutaka, additional, Tanaka, Masaru, additional, Komiya, Tatsuhiko, additional, Soga, Yoshiharu, additional, Hanyu, Michiya, additional, Domei, Takenori, additional, Ando, Kenji, additional, Kadota, Kazushige, additional, Minatoya, Kenji, additional, Nakagawa, Yoshihisa, additional, Kimura, Takeshi, additional, Matsuda, Mitsuo, additional, Takeuchi, Yuzo, additional, Mitsuoka, Hirokazu, additional, Konishi, Takashi, additional, Ootani, Seiji, additional, Fujiwara, Hisayoshi, additional, Takatsu, Yoshiki, additional, Sato, Yukihito, additional, Kataoka, Kazuaki, additional, Nohara, Ryuji, additional, Nakano, Kimisato, additional, Miyamoto, Syoichi, additional, Kunihiko, Nagai, additional, Murakami, Tomoyuki, additional, Ishida, Katsuya, additional, Nobuyoshi, Masakiyo, additional, Yamaji, Kyohei, additional, Yasumoto, Hitoshi, additional, Iwabuchi, Masashi, additional, Kato, Masayuki, additional, Tatami, Ryozo, additional, Hattori, Ryuichi, additional, Kita, Toru, additional, Kihara, Yasuki, additional, Kato, Hiroshi, additional, Aoyama, Takeshi, additional, Sakurai, Takahiro, additional, Kawanami, Masaki, additional, Suyama, Tamaki, additional, Tada, Eiji, additional, Inada, Tsukasa, additional, Uzui, Hiroyasu, additional, Nakano, Akira, additional, Lee, Jong-Dae, additional, Takizawa, Akinori, additional, Ryuzo, Nawada, additional, Shinoda, Eiji, additional, Takahashi, Masaaki, additional, Horie, Minoru, additional, Takashima, Hiroyuki, additional, Toyofuku, Mamoru, additional, Kotoura, Hajime, additional, Miura, Akira, additional, Matoba, Yoshiki, additional, Takumi, Takuro, additional, Tei, Chuwa, additional, Hamasaki, Shuichi, additional, Doi, Osamu, additional, Kambara, Hirofumi, additional, Kaburagi, Satoshi, additional, Mitsudo, Kazuaki, additional, Mizoguchi, Tetsu, additional, Akira, Yoshida, additional, Kaneda, Kazuhisa, additional, Ogawa, Hisao, additional, Sugamura, Koichi, additional, Sugiyama, Seigo, additional, Doyama, Kiyoshi, additional, Araki, Makoto, additional, Sakata, Ryuzo, additional, Ikeda, Tadashi, additional, Onoe, Masahiko, additional, Yamanaka, Kazuo, additional, Iwakura, Atsushi, additional, Fujiwara, Keiichi, additional, Soga, Kinji, additional, Matsushita, Tsutomu, additional, Nishiwaki, Noboru, additional, Yoshida, Yuichi, additional, Okada, Yukikatsu, additional, Nasu, Michihiro, additional, Koyama, Tadaaki, additional, Tanaka, Kuniyoshi, additional, Koshiji, Takaaki, additional, Morioka, Koichi, additional, Shimamoto, Mitsuomi, additional, Yamazaki, Fumio, additional, Aota, Masaki, additional, Hara, Hiroyuki, additional, Tabata, Takafumi, additional, Imoto, Yutaka, additional, Yamamoto, Hiroyuki, additional, Matsuda, Katsuhiko, additional, Nara, Masafumi, additional, Nakajima, Hiroyuki, additional, Kawasuji, Michio, additional, Moriyama, Syuji, additional, Arimura, Sakiko, additional, Fujino, Yumika, additional, Hanazawa, Miya, additional, Hibi, Chikako, additional, Kato, Risa, additional, Kinoshita, Yui, additional, Kitagawa, Kumiko, additional, Kitamura, Masayo, additional, Kuwahara, Takahiro, additional, Sachiko, Maeda, additional, Miki, Izumi, additional, Minematsu, Saeko, additional, Nishida, Satoko, additional, Okamoto, Naoko, additional, Saeki, Asuka, additional, Sasae, Hitomi, additional, Sato, Yuki, additional, Takahashi, Asuka, additional, Takinami, Emi, additional, Tezuka, Saori, additional, Tsuda, Marina, additional, Tsumori, Miyuki, additional, Uchida, Yuriko, additional, Yamamoto, Yuko, additional, Yamauchi, Misato, additional, Yamazaki, Itsuki, additional, Yoshimoto, Mai, additional, Abe, Mitsuru, additional, Fuki, Masayuki, additional, Hayano, Mamoru, additional, Kato, Eri, additional, Kato, Yoshihiro, additional, Nakajima, Tetsu, additional, Nakatsuma, Kenji, additional, Tazaki, Junichi, additional, Tokushige, Akihiro, additional, Watanabe, Hiroki, additional, Yaku, Hidenori, additional, Yamamoto, Erika, additional, and Yamashita, Yugo, additional

Published
2022
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45. Percutaneous coronary intervention using new-generation drug-eluting stents versus coronary arterial bypass grafting in stable patients with multi-vessel coronary artery disease: From the CREDO-Kyoto PCI/CABG registry Cohort-3

Author

Watanabe, Hiroki, Yamamoto, Ko, Shiomi, Hiroki, Morimoto, Takeshi, Kato, Eri, Matsumura, Yukiko, Nakatsuma, Kenji, Takeji, Yasuaki, Yaku, Hidenori, Yamamoto, Erika, Yamashita, Yugo, Yoshikawa, Yusuke, Fuki, Masayuki, Yamaji, Kyohei, Ehara, Natsuhiko, Sakamoto, Hiroki, Imada, Kazuaki, Tada, Takeshi, Taniguchi, Ryoji, Nishikawa, Ryusuke, Tada, Tomohisa, Uegaito, Takashi, Ogawa, Tatsuya, Yamada, Miho, Takeda, Teruki, Eizawa, Hiroshi, Tamura, Nobushige, Tambara, Keiichi, Suwa, Satoru, Shirotani, Manabu, Tamura, Toshihiro, Inoko, Moriaki, Nishizawa, Junichiro, Natsuaki, Masahiro, Sakai, Hiroshi, Yamamoto, Takashi, Kanemitsu, Naoki, Ohno, Nobuhisa, Ishii, Katsuhisa, Marui, Akira, Tsuneyoshi, Hiroshi, Terai, Yasuhiko, Nakayama, Shogo, Yamazaki, Kazuhiro, Takahashi, Mamoru, Tamura, Takashi, Esaki, Jiro, Miki, Shinji, Onodera, Tomoya, Mabuchi, Hiroshi, Furukawa, Yutaka, Tanaka, Masaru, Komiya, Tatsuhiko, Soga, Yoshiharu, Hanyu, Michiya, Ando, Kenji, Kadota, Kazushige, Minatoya, Kenji, Nakagawa, Yoshihisa, and Kimura, Takeshi

Subjects
Ischemic stroke, Multidisciplinary, Revascularization, Coronary angioplasty, Coronary artery bypass grafting, Drug-Eluting Stents, Coronary Artery Disease, Coronary revascularization, Cardiovascular disease risk, Stroke, Myocardial infarction, Percutaneous Coronary Intervention, Humans, Registries, Coronary Artery Bypass, Coronary stenting
Abstract

Aims There is a scarcity of studies comparing percutaneous coronary intervention (PCI) using new-generation drug-eluting stents (DES) with coronary artery bypass grafting (CABG) in patients with multi-vessel coronary artery disease. Methods and results The CREDO-Kyoto PCI/CABG registry Cohort-3 enrolled 14927 consecutive patients who underwent first coronary revascularization with PCI or isolated CABG between January 2011 and December 2013. The current study population consisted of 2464 patients who underwent multi-vessel coronary revascularization including revascularization of left anterior descending coronary artery (LAD) either with PCI using new-generation DES (N = 1565), or with CABG (N = 899). Patients in the PCI group were older and more often had severe frailty, but had less complex coronary anatomy, and less complete revascularization than those in the CABG group. Cumulative 5-year incidence of a composite of all-cause death, myocardial infarction or stroke was not significantly different between the 2 groups (25.0% versus 21.5%, P = 0.15). However, after adjusting confounders, the excess risk of PCI relative to CABG turned to be significant for the composite endpoint (HR 1.27, 95%CI 1.04–1.55, P = 0.02). PCI as compared with CABG was associated with comparable adjusted risk for all-cause death (HR 1.22, 95%CI 0.96–1.55, P = 0.11), and stroke (HR 1.17, 95%CI 0.79–1.73, P = 0.44), but with excess adjusted risk for myocardial infarction (HR 1.58, 95%CI 1.05–2.39, P = 0.03), and any coronary revascularization (HR 2.66, 95%CI 2.06–3.43, P Conclusions In this observational study, PCI with new-generation DES as compared with CABG was associated with excess long-term risk for major cardiovascular events in patients who underwent multi-vessel coronary revascularization including LAD.

Published
2022
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