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Osteoporosis is a disease characterised by a reduction in bone strength due to increased porosity and impaired mineralisation. In our study, we investigated whether muscle strength and mass exert a significant effect on bone mineral density in young adult women. We also tested whether sclerostin can be used as an indicator in the assessment of bone mineralisation. The study included 111 patients. All patients had their bone mineral density determined in the L1–L4 section of the lumbar spine and in the whole skeleton. The parameters of fat mass (FM), lean body mass (LBM) and visceral fat mass (VF) were also determined. Metabolic activity of osteocytes was assessed by measuring the serum sclerostin concentration. There was a statistically significant association of both hands’ muscle strength with all parameters expressing bone mineralisation. A statistically significant relationship was also obtained between BMD L1–L4 and the body mass components (FM, LBM). Sclerostin levels in the study did not differ between groups with normal and reduced bone mineral density. Muscle strength assessment may be a potential exponent of reduced bone mineral density, also used clinically in young adult women. The utility of sclerostin in the clinical assessment of bone mineralisation has not been demonstrated.

Eating disorders are a significant medical and social problem. The most commonly diagnosed eating disorders include anorexia nervosa (AN) and bulimia nervosa, currently classified as behavioral disorders. Anorexia nervosa is a disease consisting in deliberate weight loss and disturbed its image and dysmorphophobia, often coexisting with symptoms of depression and social withdrawal. Understanding the problem of anorexia is not just about food or body mass. Underlying disorders include, among others: emotional problems, the need to define your own identity, a negative image of yourself. AN in women in the general population occurs at a frequency of 0.5-1%, in men 0.05-0.1%, in Poland it ranges from 0.8% -1,8% of the population of girls