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3. Kidney and Cardiovascular Effects of Canagliflozin According to Age and Sex: A Post Hoc Analysis of the CREDENCE Randomized Clinical Trial

Author

Perkovic, Vlado, Mahaffey, Kenneth W., Agarwal, Rajiv, Bakris, George, Brenner, Barry M., Cannon, Christopher P., Charytan, David M., de Zeeuw, Dick, Greene, Tom, Jardine, Meg J., Heerspink, Hiddo J.L., Levin, Adeera, Meininger, Gary, Neal, Bruce, Pollock, Carol, Wheeler, David C., Zhang, Hong, Zinman, Bernard, Jardine, Meg, Li, Nicole, Kolesnyk, Inna, Aizenberg, Diego, Pecoits-Filho, Roberto, Cherney, David, Obrador, Gregorio, Chertow, Glenn, Chang, Tara, Hawley, Carmel, Ji, Linong, Wada, Takashi, Jha, Vivekanand, Lim, Soo Kun, Lim-Abrahan, Mary Anne, Santos, Florence, Chae, Dong-Wan, Hwang, Shang-Jyh, Vazelov, Evgueniy, Rychlík, Ivan, Hadjadj, Samy, Krane, Vera, Rosivall, László, De Nicola, Luca, Dreval, Alexander, Nowicki, Michał, Schiller, Adalbert, Distiller, Larry, Górriz, Jose L., Kolesnyk, Mykola, David, Wheeler, C., Guerrero, Rodolfo Andres Ahuad, Albisu, Juan Pablo, Alvarisqueta, Andres, Bartolacci, Ines, Berli, Mario Alberto, Bordonava, Anselmo, Calella, Pedro, Cantero, Maria Cecilia, Cartasegna, Luis Rodolfo, Cercos, Esteban, Coloma, Gabriela Cecilia, Colombo, Hugo, Commendatore, Victor, Cuadrado, Jesus, Cuneo, Carlos Alberto, Cusumano, Ana Maria, Douthat, Walter Guillermo, Dran, Ricardo Dario, Farias, Eduardo, Fernandez, Maria Florencia, Finkelstein, Hernan, Fragale, Guillermo, Fretes, Jose Osvaldo, Garcia, Nestor Horacio, Gastaldi, Anibal, Gelersztein, Elizabeth, Glenny, Jorge Archibaldo, Gonzalez, Joaquin Pablo, Colaso, Patricia del Carmen Gonzalez, Goycoa, Claudia, Greloni, Gustavo Cristian, Guinsburg, Adrian, Hermida, Sonia, Juncos, Luis Isaias, Klyver, Maria Isabel, Kraft, Florencia, Krynski, Fernando, Lanchiotti, Paulina Virginia, Leon de la Fuente, Ricardo Alfonso, Marchetta, Nora, Mele, Pablo, Nicolai, Silvia, Novoa, Pablo Antonio, Orio, Silvia Ines, Otreras, Fabian, Oviedo, Alejandra, Raffaele, Pablo, Resk, Jorge Hector, Rista, Lucas, Papini, Nelson Rodriguez, Sala, Jorgelina, Santos, Juan Carlos, Schiavi, Lilia Beatriz, Sessa, Horacio, Casabella, Tomas Smith, Ulla, Maria Rosa, Valdez, Maria, Vallejos, Augusto, Villarino, Adriana, Visco, Virginia Esther, Wassermann, Alfredo, Zaidman, Cesar Javier, Cheung, Ngai Wah, Droste, Carolyn, Fraser, Ian, Johnson, David, Mah, Peak Mann, Nicholls, Kathy, Packham, David, Proietto, Joseph, Roberts, Anthony, Roger, Simon, Tsang, Venessa, Raduan, Roberto Abrão, Costa, Fernando Augusto Alves da, Amodeo, Celso, Turatti, Luiz Alberto Andreotti, Bregman, Rachel, Sanches, Fernanda Cristina Camelo, Canani, Luis Henrique, Chacra, Antônio Roberto, Borges, João Lindolfo Cunha, Vêncio, Sérgio Alberto Cunha, Franco, Roberto Jorge da Silva, d’Avila, Domingos, Portes, Evandro de Souza, de Souza, Pedro, Deboni, Luciane Mônica, Fraige Filho, Fadlo, Neto, Bruno Geloneze, Gomes, Marcus, Kohara, Suely Keiko, Keitel, Elizete, Saraiva, Jose Francisco Kerr, Lisboa, Hugo Roberto Kurtz, Contieri, Fabiana Loss de Carvalho, Milagres, Rosângela, Junior, Renan Montenegro, de Brito, Claudia Moreira, Hissa, Miguel Nasser, Sabbag, Ângela Regina Nazario, Noronha, Irene, Panarotto, Daniel, Filho, Roberto Pecoits, Pereira, Márcio Antônio, Saporito, Wladmir, Scotton, Antonio Scafuto, Schuch, Tiago, de Almeida, Roberto Simões, Ramos, Cássio Slompo, Felício, João Soares, Thomé, Fernando, Hachmann, Jean Carlo Tibes, Yamada, Sérgio, Hayashida, Cesar Yoiti, Petry, Tarissa Beatrice Zanata, Zanella, Maria Teresa, Andreeva, Viktoria, Angelova, Angelina, Dimitrov, Stefan, Genadieva, Veselka, Genova-Hristova, Gabriela, Hristozov, Kiril, Kamenov, Zdravko, Koundurdjiev, Atanas, Lozanov, Lachezar, Margaritov, Viktor, Nonchev, Boyan, Rangelov, Rangel, Shinkov, Alexander, Temelkova, Margarita, Velichkova, Ekaterina, Yakov, Andrian, Aggarwal, Naresh, Aronson, Ronnie, Bajaj, Harpreet, Chouinard, Guy, Conway, James, Cournoyer, Serge, DaRoza, Gerald, De Serres, Sacha, Dubé, François, Goldenberg, Ronald, Gupta, Anil, Gupta, Milan, Henein, Sam, Khandwala, Hasnain, Leiter, Lawrence, Madore, François, McMahon, Alan, Muirhead, Norman, Pichette, Vincent, Rabasa-Lhoret, Remi, Steele, Andrew, Tangri, Navdeep, Torshizi, Ali, Woo, Vincent, Zalunardo, Nadia, Montenegro, María Alicia Fernández, Gonzalo Godoy Jorquera, Juan, Fariña, Marcelo Medina, Gajardo, Victor Saavedra, Vejar, Margarita, Chen, Nan, Chen, Qinkai, Gan, Shenglian, Kong, Yaozhong, Li, Detian, Li, Wenge, Li, Xuemei, Lin, Hongli, Liu, Jian, Lu, Weiping, Mao, Hong, Ren, Yan, Song, Weihong, Sun, Jiao, Sun, Lin, Tu, Ping, Wang, Guixia, Yang, Jinkui, Yin, Aiping, Yu, Xueqing, Zhao, Minghui, Zheng, Hongguang, Mendoza, Jose Luis Accini, Arcos, Edgar, Avendano, Jorge, Diaz Ruiz, Jorge Ernesto Andres, Ortiz, Luis Hernando Garcia, Gonzalez, Alexander, Triana, Eric Hernandez, Higuera, Juan Diego, Malaver, Natalia, de Salazar, Dora Inés Molina, Rosero, Ricardo, Alexandra Terront Lozano, Monica, Cometa, Luis Valderrama, Valenzuela, Alex, Vargas Alonso, Ruben Dario, Villegas, Ivan, Yupanqui, Hernan, Bartaskova, Dagmar, Barton, Petr, Belobradkova, Jana, Dohnalova, Lenka, Drasnar, Tomas, Ferkl, Richard, Halciakova, Katarina, Klokocnikova, Vera, Kovar, Richard, Lastuvka, Jiri, Lukac, Martin, Pesickova, Satu, Peterka, Karel, Pumprla, Jiri, Rychlik, Ivan, Saudek, Frantisek, Tesar, Vladimir, Valis, Martin, Weiner, Pavel, Zemek, Stanislav, Alamartine, Eric, Borot, Sophie, Cariou, Bertrand, Dussol, Bertrand, Fauvel, Jean-Pierre, Gourdy, Pierre, Klein, Alexandre, Le Meur, Yannick, Penfornis, Alfred, Roussel, Ronan, Saulnier, Pierre-Jean, Thervet, Eric, Zaoui, Philippe, Burst, Volker, Faghih, Markus, Faulmann, Grit, Haller, Hermann, Jerwan-Keim, Reinhold, Maxeiner, Stephan, Paschen, Björn, Plassmann, Georg, Rose, Ludger, Gonzalez Orellana, Ronaldo Arturo, Haase, Franklin Paul, Moreira Diaz, Juan Pablo, Ramirez Roca, Luis Alberto, Sánchez Arenales, Jose Antonio, Sanchez Polo, José Vicente, Juarez, Erick Turcios, Csecsei, Gyongyi, Csiky, Botond, Danos, Peter, Deak, Laszlo, Dudas, Mihaly, Harcsa, Eleonora, Keltai, Katalin, Keresztesi, Sandor, Kiss, Krisztian, Konyves, Laszlo, Major, Lajos, Mileder, Margit, Molnar, Marta, Mucsi, Janos, Oroszlan, Tamas, Ory, Ivan, Paragh, Gyorgy, Peterfai, Eva, Petro, Gizella, Revesz, Katalin, Takacs, Robert, Vangel, Sandor, Vasas, Szilard, Zsom, Marianna, Abraham, Oomman, Bhushan, Raju Sree, Deepak, Dewan, Edwin, Fernando M., Gopalakrishnan, Natarajan, Gracious, Noble, Hansraj, Alva, Jain, Dinesh, Keshavamurthy, C.B., Khullar, Dinesh, Manisha, Sahay, Peringat, Jayameena, Prasad, Narayan, Satyanarayana, Rao K., Sreedhar, Reddy, Sreelatha, Melemadathil, Sudhakar, Bhimavarapu, Chandra Vyasam, Ramesh, Bonadonna, Riccardo, Castellino, Pietro, Ceriello, Antonio, Chiovato, Luca, De Cosmo, Salvatore, Derosa, Giuseppe, Di Carlo, Alberto, Di Cianni, Graziano, Frascà, Giovanni, Fuiano, Giorgio, Gambaro, Giovanni, Garibotto, Giacomo, Giorda, Carlo, Malberti, Fabio, Mandreoli, Marcora, Mannucci, Edoardo, Orsi, Emanuela, Piatti, Piermarco, Santoro, Domenico, Sasso, Ferdinando Carlo, Serviddio, Gaetano, Stella, Andrea, Trevisan, Roberto, Veronelli, Anna Maria, Zanoli, Luca, Akiyama, Hitoshi, Aoki, Hiromi, Asano, Akimichi, Iitsuka, Tadashi, Kajiyama, Shizuo, Kashine, Susumu, Kawada, Toshio, Kodera, Takamoto, Kono, Hiroshi, Koyama, Kazunori, Kumeda, Yasuro, Miyauchi, Shozo, Mizuyama, Kazuyuki, Niiya, Tetsuji, Oishi, Hiroko, Ota, Satoshi, Sakakibara, Terue, Takai, Masahiko, Tomonaga, Osamu, Tsujimoto, Mitsuru, Wakasugi, Masakiyo, Wakida, Yasushi, Watanabe, Takayuki, Yamada, Masayo, Yanagida, Kazuhiro, Yanase, Toshihiko, Yumita, Wataru, Gaupsiene, Egle, Kozloviene, Dalia, Navickas, Antanas, Urbanaviciene, Egle, Abdul Ghani, Rohana, Kadir, Khalid Abdul, Ali, Norsiah, Che Yusof, Mohd Daud, Gan, Chye Lee, Ismail, Mastura, Kong, Wei Yen, Lam, Swee Win, Lee, Li Yuan, Loh, Chek Loong, Manocha, Anita Bhajan, Ng, Kee Sing, Ahmad, Nik Nur Fatnoon Nik, Ratnasingam, Vanassa, Shudim, Saiful Shahrizal Bin, Vengadasalam, Paranthaman, Abraira Munoz, Luis David, Salazar, Melchor Alpizar, Cruz, Juan Baas, Soto, Mario Burgos, Ramos, Jose Chevaile, Wong, Alfredo Chew, Correa Rotter, Jose Ricardo, Escalante, Tonatiu Diaz, Enriquez Sosa, Favio Edmundo, Lozano, Fernando Flores, Flota Cervera, Luis Fernando, Baron, Paul Frenk, Ballesteros, Cecilia Garcia, Gomez Rangel, Jose David, Herrera Jimenez, Luis Enrique, Irizar Santana, Sergio Saul, Flores, Fernando Jimenez, Molina, Hugo Laviada, Luna Ceballos, Rosa Isela, del Campo Blanco, Belia Martin, Franco, Guadalupe Morales, Moreno Loza, Oscar Tarsicio, Rocha, Cynthia Mustieles, Vera, Gregorio Obrador, Castellanos, Ricardo Orozco, Calcaneo, Juan Peralta, Reyes Rosano, Miguel Angel, Pattzi, Hiromi Rodriguez, Guzman, Juan Rosas, Rucker Joerg, Isabel Erika, Saavedra Sanchez, Sandra Berenice, Sanchez Mijangos, Jose Hector, Sanson, Pablo Serrano, Tamayo y Orozco, Juan Alfredo, Chavez, Eloisa Tellez, Cepeda, Alejandro Valdes, Carrillo, Luis Venegas, Mesa, Juan Villagordoa, Escobedo, Rolando Zamarripa, Baker, John, Noonan, Paul, Scott, Russell, Walker, Robert, Watson, Edward, Williams, Michael, Young, Simon, Abejuela, Zaynab, Agra, Jeimeen, Aquitania, Grace, Caringal, Clodoaido, Comia, Rhea Severina, Santos, Lalaine Delos, Gomez, Olivert, Jimeno, Cecilia, Tan, Gerry, Tolentino, Marsha, Yao, Christy, Yap, Yvette Ethel, Lallaine Ygpuara, Ma. Dovie, Bijata-Bronisz, Renata, Hotlos, Lucyna, Januszewicz, Andrzej, Kaczmarek, Barbara, Kaminska, Anna, Lazuka, Lech, Madej, Andrzej, Mazur, Stanislaw, Mlodawska-Choluj, Dorota, Nowicki, Michal, Orlowska-Kowalik, Grazyna, Popenda, Grazyna, Rewerska, Barbara, Sowinski, Dariusz, Angelescu, Liliana Monica, Anghel, Veronica, Avram, Rodica-Ioana, Busegeanu, Mihaela-Magdalena, Cif, Adriana, Cosma, Dana, Crisan, Carmen, Demian, Luiza Despina, Ferariu, Ioana Emilia, Halmagyi, Ildiko, Hancu, Nicolae, Munteanu, Mircea, Negru, Doru, Onaca, Adriana Gabriela, Petrica, Ligia, Popa, Amorin Remus, Ranetti, Aurelian-Emil, Serafinceanu, Cristian, Toarba, Cristina, Agafyina, Alina, Barbarash, Olga, Barysheva, Olga, Chizhov, Daniil, Dobronravov, Vladimir, Glinkina, Irina, Grineva, Elena, Khirmanov, Vladimir, Kolmakova, Elena, Koroleva, Tatiana, Kvitkova, Liudmila, Marasaev, Viacheslav, Mkrtumyan, Ashot, Morugova, Tatiana, Nagibovich, Galina, Nagibovich, Oleg, Nedogoda, Sergei, Osipova, Irina, Raskina, Tatiana, Samoylova, Yulia, Sazonova, Olga, Shamkhalova, Minara, Shutemova, Elena, Shwartz, Yuriy, Uriasyev, Oleg, Vorobyev, Sergey, Zateyshchikova, Anna, Zateyshshikov, Dmitry, Zykova, Tatyana, Antic, Slobodan, Djordjevic, Miodrag, Kendereski, Aleksandra, Lalic, Katarina, Lalic, Nebojsa, Popovic-Radinovic, Vesna, Babikova, Jana, Benusova, Olga, Buganova, Ingrid, Culak, Jan, Dzupina, Andrej, Dzuponova, Jana, Fulop, Peter, Ilavska, Adriana, Martinka, Emil, Ochodnicka, Zuzana, Pella, Daniel, Smatanova, Iveta, Ahmed, Fayzal, Badat, Aysha, Breedt, Johannes, Distiller, Lawrence, Govender, Vimladhevi, Govender, Ravendran, Joshi, Mukesh, Jurgens, Jaco, Latiff, Gulam, Lombard, Landman, Mookadam, Mohamed, Ngcakani, Nomangesi, Nortje, Hendrik, Oosthuizen, Helena, Pillay-Ramaya, Larisha, Prozesky, Hans, Reddy, Jeevren, Rheeder, Paul, Seeber, Mary, Cho, Young Min, Jeong, In-Kyung, Kim, Sin Gon, Kim, Yeong Hoon, Kwon, Hyuk-Sang, Kwon, Min Jeong, Lee, Byung-Wan, Lee, JungEun, Lee, Moon-Kyu, Nam, Moon-Suk, Oh, Kook-Hwan, Park, Cheol- Young, Park, Sun-Hee, Yoon, Kun Ho, Garcia, Pere Alvarez, Mercadal, Luis Asmarats, Barrios, Clara, Castro, Fernando Cereto, Guldris, Secundino Cigarran, Lopez, Marta Dominguez, Egido de los Rios, Jesus, Fresnedo, Gema Fernandez, Serrano, Antonio Galan, Garcia, Isabel, Gonzalez Martinez, Francisco Javier, Jodar Gimeno, Jose Esteban, Mendoza, Manuel Lopez, Marin, Tamara Malek, Portillo, Cristobal Morales, Munar Vila, Maria Antonia, Torres, Manuel Muñoz, Iglesias, Javier Nieto, Perez, Jonay Pantoja, Vera, Merce Perez, Portoles Perez, Jose M., Quesada Simón, María Angustias, Canonge, Rafael Simo, Gonzalez, Alfonso Soto, Riera, Manel Terns, Tinahones Madueno, Francisco Jose, Plaza, Mercedes Velo, Chang, Chwen-Tzuei, Chuang, Lee-Ming, Hsia, Te-Lin, Hsieh, Chang-Hsun, Lin, Chih-Ching, Lu, Yung- Chuan, Sheu, Wayne H-H, Barna, Olga, Bilyk, Svitlana D., Botsyurko, Volodymyr, Dudar, Iryna, Fushtey, Ivan, Godlevska, Olga, Golovchenko, Oleksandr, Gyrina, Olga, Kazmirchuk, Anatoliy, Komisarenko, Iuliia, Korzh, Oleksii, Kravchun, Nonna, Legun, Oleg, Mankovskyy, Borys, Martynyuk, Liliya, Mostovoy, Yuriy, Pashkovska, Nataliia, Pererva, Larysa, Pertseva, Tetyana, Samoylov, Oleksandr, Smirnov, Ivan, Svyshchenko, Yevgeniya, Tomashkevych, Halyna, Topchii, Ivan, Tryshchuk, Nadiya, Tseluyko, Vira, Vizir, Vadym, Vlasenko, Maryna, Zlova, Tetiana, Zub, Liliia, Abusnana, Salah, Railey, Mohamed, Abouglila, Kamal, Ainsworth, Paul, Ali, Zishan, Arutchelvam, Vijayaraman, Barnard, Maria, Bellary, Srikanth, Davies, Emyr, Davies, Mark, Davies, Simon, Dawson, Alison, El Kossi, Mohsen, English, Patrick, Fraser, Donald, Gnudi, Luigi, Gunstone, Anthony, Hall, Timothy, Hanif, Wasim, Jackson, Alan, Johnson, Andrew, Joseph, Franklin, Krishnan, Singhan, Kumwenda, Mick, MacDougall, Iain, Nixon, Paul, O'Hare, Joseph, Philip, Sam, Ramtoola, Shenaz, Saxena, Manish, Sennik, Davesh, Simon, Godwin, Singh, Baldev, Stephens, Jeffrey, Strzelecka, Anna, Symonds, Rehan, Turner, Wayne, Wahba, Mona, Wakeling, John, Wheeler, David, Winocour, Peter, Abdallah, Joseph, Abdullah, Raied, Abramowitz, Matthew, Acosta, Idalia, Aiello, Joseph, Akright, Laura, Akyea-Djamson, Ayim, Alappan, Rajendran, Alicic, Radica, Al-Karadsheh, Amer, Allison, Dale Crawford, Arauz-Pacheco, Carlos, Arfeen, Shahabul, Arif, Ahmed, Arvind, Moogali, Atray, Naveen, Awad, Ahmed, Barnhill, Peggy, Barranco, Elizabeth, Barrera, Carlos, Beacom, Matthew, Behara, Venkata, Belo, Diogo, Bentley-Lewis, Rhonda, Berenguer, Ramon, Bermudez, Lidia, Bernardo, Marializa, Biscoveanu, Mihaela, Bowman-Stroud, Cynthia, Brandon, Donald, Brusco, Osvaldo, Busch, Robert, Canaan, Yamil, Chilito, Alicia, Christensen, Tom, Christiano, Cynthia, Christofides, Elena, Chuateco, Caroucel, Cohen, Kenneth, Cohen, Robert, Cohen-Stein, Debbie, Cook, Charles, Coyne, Daniel, Daboul, Nizar, Darwish, Riad, Daswani, Adarsh, Deck, Kenneth, Desouza, Cyrus, Dev, Devasmita, Dhillon, Monika, Dua, Sohan, Eder, Frank, Elosegui, Ana Maria, El-Shahawy, Mohamed, Ervin, John, Esquenazi, Alberto, Evans, John, Fishbane, Steven, Frias, Juan, Galindo-Ramos, Eugenia, Galphin, Claude, Ghazi, Adline, Gonzalez, Enrique, Gorson, David, Gowda, Anupama, Greco, Barbara, Grubb, Stephen, Gulati, Rakesh, Hammoud, Jamal, Handelsman, Stuart, Hartman, Israel, Hershon, Kenneth, Hiser, Daniel, Hon, George, Jacob, Radu, Jaime, Maria, Jamal, Aamir, Kaupke, Charles, Keightley, Gerald, Kern, Elizabeth, Khanna, Rakhi, Khitan, Zeid, Kim, Sun, Kopyt, Nelson, Kovesdy, Csaba, Krishna, Gopal, Kropp, Jeffrey (Jay), Kumar, Amrendra, Kumar, Jayant, Kumar, Neil, Kusnir, Jorge, Lane, Wendy, Lawrence, Mary, Lehrner, Lawrence, Lentz, John, Levinson, Dennis, Lewis, Derek, Liss, Kenneth, Maddux, Andreas, Maheshwari, Hiralal, Mandayam, Sreedhar, Marar, Isam, Mehta, Bhasker, Middleton, John, Mordujovich, Jorge, Moreda, Ramon, Moustafa, Moustafa, Trenche, Samuel Mujica, Narayanan, Mohanram, Narvarte, Javier, Nassar, Tareq, Newman, George, Nichol, Brian, Nicol, Philip, Nisnisan, Josier, Nossuli, A. Kaldun, Obialo, Chamberlain, Olelewe, Sarah, Oliver, Michael, O'Shaughnessy, Andrew, Padron, John, Pankhaniya, Rohit, Parker, Reginald, Patel, Devesh, Patel, Gnyandev, Patel, Nina, Pavon, Humberto, Perez, Armando, Perez, Carlos, Perlman, Alan, Pettis, Karlton, Pharr, Walter, Phillips, Andrea, Purighalla, Raman, Quesada-Suarez, Luis, Ranjan, Rajiv, Rastogi, Sanjeev, Reddy, Jakkidi, Rendell, Marc, Rich, Lisa, Robinson, Michael, Rodriguez, Hector, Rosas, Sylvia, Saba, Fadi, Sankaram, Rallabhandi, Sarin, Ravi, Schreiman, Robert, Scott, David, Sekkarie, Mohamed, Sensenbrenner, John, Shakeel, Muhammad, Shanik, Michael, Shaw, Sylvia, Smith, Stephen, Solomon, Richard, Sprague, Amy, Spry, Leslie, Suchinda, Pusadee, Sultan, Senan, Surampudi, Prasanth, Sussman, Sherry, Tan, Anjanette, Terrelonge, Antonio, Thompson, Michael, Trespalacios, Fernando, Trippe, Bruce, Trueba, Pilar, Twahirwa, Marcel, Updegrove, John, Van Buren, Peter, Vannorsdall, Mark, Varghese, Freemu, Velasquez-Mieyer, Pedro, Ventrapragada, Sailaja, Vukotic, Goga, Wadud, Khurram, Warren, Mark, Watson, Henry, Watts, Ronald, Weiner, Daniel, Welker, James, Welsh, Jean, Williams, Shelley, Zaniewski-Singh, Michelle, Yi, Tae Won, Smyth, Brendan, Di Tanna, Gian Luca, Arnott, Clare, Cardoza, Kathryn, and Kang, Amy

Published
2023
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5. Clinical Evaluation of AMNIODERM+ ® Wound Dressing Containing Non-Viable Human Amniotic Membrane: Retrospective-Perspective Clinical Trial.

Author

Schmiedova, Iveta, Slama, Petr, Dembickaja, Alena, Kozova, Beata, Hyneckova, Vendula, Gogolkova, Sona, Stastna, Elen, Zahradnicek, Michal, Savic, Stefan, Davani, Arash, Hulo, Edward, and Martinka, Emil

Subjects
DIABETIC foot, AMNION, CHRONIC wounds & injuries, LEG amputation, WOUND healing, HEALING
Abstract

Chronic wounds result from the body's inability to heal, causing pain, pathogen entry, limited treatment options, and societal burden. Diabetic foot ulcers are particularly challenging, often leading to severe complications like leg amputation. A clinical study tested AMNIODERM+®, a new device with a lyophilized human amniotic membrane (HAM), on chronic diabetic foot ulcers. Participants had diabetic neuropathic or neuroischemic leg wounds (2–16 cm2) unhealed by 20% after six weeks of standard care. This study showed significant wound healing improvements with AMNIODERM+®. The median wound size reduction after 12 weeks was 95.5%, far exceeding the null hypothesis of 20% change. Additionally, 65% of patients achieved complete ulceration healing, surpassing the 50% efficacy requirement. The median time to full closure was 11.4 weeks, with the proportion of completely healed patients rising progressively, reaching 55% by week 11. These findings, from the clinical trial "Freeze-dried amniotic membrane in the treatment of nonhealing wounds", suggest AMNIODERM+® as a promising future treatment for chronic diabetic foot ulcers. The published results were obtained as part of a clinical trial entitled "Freeze-dried amniotic membrane in the treatment of nonhealing wounds: a single-arm, retrospectively-perspective clinical trial", EUDAMED Nr. CIV-SK-22-10-041146. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Worldwide inertia to the use of cardiorenal protective glucose-lowering drugs (SGLT2i and GLP-1 RA) in high-risk patients with type 2 diabetes

Author

Schernthaner, Guntram, Shehadeh, Naim, Ametov, Alexander S., Bazarova, Anna V., Ebrahimi, Fahim, Fasching, Peter, Janež, Andrej, Kempler, Péter, Konrāde, Ilze, Lalić, Nebojša M., Mankovsky, Boris, Martinka, Emil, Rahelić, Dario, Serafinceanu, Cristian, Škrha, Jan, Tankova, Tsvetalina, and Visockienė, Žydrūnė

Published
2020
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13. Effect of SGLT2 Inhibitors on Stroke and Atrial Fibrillation in Diabetic Kidney Disease

Author

Zhou, Zien, primary, Jardine, Meg J., additional, Li, Qiang, additional, Neuen, Brendon L., additional, Cannon, Christopher P., additional, de Zeeuw, Dick, additional, Edwards, Robert, additional, Levin, Adeera, additional, Mahaffey, Kenneth W., additional, Perkovic, Vlado, additional, Neal, Bruce, additional, Lindley, Richard I., additional, Ahuad Guerrero, Rodolfo Andres, additional, Aizenberg, Diego, additional, Albisu, Juan Pablo, additional, Alvarisqueta, Andres, additional, Bartolacci, Ines, additional, Berli, Mario Alberto, additional, Bordonava, Anselmo, additional, Calella, Pedro, additional, Cantero, Maria Cecilia, additional, Cartasegna, Luis Rodolfo, additional, Cercos, Esteban, additional, Coloma, Gabriela Cecilia, additional, Colombo, Hugo, additional, Commendatore, Victor, additional, Cuadrado, Jesus, additional, Cuneo, Carlos Alberto, additional, Cusumano, Ana Maria, additional, Douthat, Walter Guillermo, additional, Dran, Ricardo Dario, additional, Farias, Eduardo, additional, Fernandez, Maria Florencia, additional, Finkelstein, Hernan, additional, Fragale, Guillermo, additional, Fretes, Jose Osvaldo, additional, Garcia, Nestor Horacio, additional, Gastaldi, Anibal, additional, Gelersztein, Elizabeth, additional, Glenny, Jorge Archibaldo, additional, Gonzalez, Joaquin Pablo, additional, del Carmen Gonzalez Colaso, Patricia, additional, Goycoa, Claudia, additional, Greloni, Gustavo Cristian, additional, Guinsburg, Adrian, additional, Hermida, Sonia, additional, Juncos, Luis Isaias, additional, Klyver, Maria Isabel, additional, Kraft, Florencia, additional, Krynski, Fernando, additional, Lanchiotti, Paulina Virginia, additional, Leon de la Fuente, Ricardo Alfonso, additional, Marchetta, Nora, additional, Mele, Pablo, additional, Nicolai, Silvia, additional, Novoa, Pablo Antonio, additional, Orio, Silvia Ines, additional, Otreras, Fabian, additional, Oviedo, Alejandra, additional, Raffaele, Pablo, additional, Resk, Jorge Hector, additional, Rista, Lucas, additional, Rodriguez Papini, Nelson, additional, Sala, Jorgelina, additional, Santos, Juan Carlos, additional, Schiavi, Lilia Beatriz, additional, Sessa, Horacio, additional, Smith Casabella, Tomas, additional, Ulla, Maria Rosa, additional, Valdez, Maria, additional, Vallejos, Augusto, additional, Villarino, Adriana, additional, Visco, Virginia Esther, additional, Wassermann, Alfredo, additional, Zaidman, Cesar Javier, additional, Cheung, Ngai Wah, additional, Droste, Carolyn, additional, Fraser, Ian, additional, Johnson, David, additional, Mah, Peak Mann, additional, Nicholls, Kathy, additional, Packham, David, additional, Proietto, Joseph, additional, Roberts, Anthony, additional, Roger, Simon, additional, Tsang, Venessa, additional, Abrão Raduan, Roberto, additional, Alves da Costa, Fernando Augusto, additional, Amodeo, Celso, additional, Andreotti Turatti, Luiz Alberto, additional, Bregman, Rachel, additional, Camelo Sanches, Fernanda Cristina, additional, Canani, Luis Henrique, additional, Chacra, Antônio Roberto, additional, Cunha Borges, João Lindolfo, additional, Cunha Vêncio, Sérgio Alberto, additional, da Silva Franco, Roberto Jorge, additional, d’Avila, Domingos, additional, de Souza Portes, Evandro, additional, de Souza, Pedro, additional, Deboni, Luciane Mônica, additional, Fraige Filho, Fadlo, additional, Geloneze Neto, Bruno, additional, Gomes, Marcus, additional, Keiko Kohara, Suely, additional, Keitel, Elizete, additional, Kerr Saraiva, Jose Francisco, additional, Kurtz Lisboa, Hugo Roberto, additional, Loss de Carvalho Contieri, Fabiana, additional, Milagres, Rosângela, additional, Montenegro Junior, Renan, additional, Moreira de Brito, Claudia, additional, Nasser Hissa, Miguel, additional, Nazario Sabbag, Ângela Regina, additional, Noronha, Irene, additional, Panarotto, Daniel, additional, Pecoits Filho, Roberto, additional, Pereira, Márcio Antônio, additional, Saporito, Wladmir, additional, Scafuto Scotton, Antonio, additional, Schuch, Tiago, additional, Simões de Almeida, Roberto, additional, Slompo Ramos, Cássio, additional, Soares Felício, João, additional, Thomé, Fernando, additional, Tibes Hachmann, Jean Carlo, additional, Yamada, Sérgio, additional, Yoiti Hayashida, Cesar, additional, Zanata Petry, Tarissa Beatrice, additional, Zanella, Maria Teresa, additional, Andreeva, Viktoria, additional, Angelova, Angelina, additional, Dimitrov, Stefan, additional, Genadieva, Veselka, additional, Genova-Hristova, Gabriela, additional, Hristozov, Kiril, additional, Kamenov, Zdravko, additional, Koundurdjiev, Atanas, additional, Lozanov, Lachezar, additional, Margaritov, Viktor, additional, Nonchev, Boyan, additional, Rangelov, Rangel, additional, Shinkov, Alexander, additional, Temelkova, Margarita, additional, Velichkova, Ekaterina, additional, Yakov, Andrian, additional, Aggarwal, Naresh, additional, Aronson, Ronnie, additional, Bajaj, Harpreet, additional, Cherney, David, additional, Chouinard, Guy, additional, Conway, James, additional, Cournoyer, Serge, additional, DaRoza, Gerald, additional, De Serres, Sacha, additional, Dubé, François, additional, Goldenberg, Ronald, additional, Gupta, Anil, additional, Gupta, Milan, additional, Henein, Sam, additional, Khandwala, Hasnain, additional, Leiter, Lawrence, additional, Madore, François, additional, McMahon, Alan, additional, Muirhead, Norman, additional, Pichette, Vincent, additional, Rabasa-Lhoret, Remi, additional, Steele, Andrew, additional, Tangri, Navdeep, additional, Torshizi, Ali, additional, Woo, Vincent, additional, Zalunardo, Nadia, additional, Fernández Montenegro, María Alicia, additional, Godoy Jorquera, Juan Gonzalo, additional, Medina Fariña, Marcelo, additional, Saavedra Gajardo, Victor, additional, Vejar, Margarita, additional, Chen, Nan, additional, Chen, Qinkai, additional, Gan, Shenglian, additional, Kong, Yaozhong, additional, Li, Detian, additional, Li, Wenge, additional, Li, Xuemei, additional, Lin, Hongli, additional, Liu, Jian, additional, Lu, Weiping, additional, Mao, Hong, additional, Ren, Yan, additional, Song, Weihong, additional, Sun, Jiao, additional, Sun, Lin, additional, Tu, Ping, additional, Wang, Guixia, additional, Yang, Jinkui, additional, Yin, Aiping, additional, Yu, Xueqing, additional, Zhao, Minghui, additional, Zheng, Hongguang, additional, Accini Mendoza, Jose Luis, additional, Arcos, Edgar, additional, Avendano, Jorge, additional, Diaz Ruiz, Jorge Ernesto Andres, additional, Garcia Ortiz, Luis Hernando, additional, Gonzalez, Alexander, additional, Hernandez Triana, Eric, additional, Higuera, Juan Diego, additional, Malaver, Natalia, additional, Molina de Salazar, Dora Inés, additional, Rosero, Ricardo, additional, Terront Lozano, Monica Alexandra, additional, Valderrama Cometa, Luis, additional, Valenzuela, Alex, additional, Vargas Alonso, Ruben Dario, additional, Villegas, Ivan, additional, Yupanqui, Hernan, additional, Bartaskova, Dagmar, additional, Barton, Petr, additional, Belobradkova, Jana, additional, Dohnalova, Lenka, additional, Drasnar, Tomas, additional, Ferkl, Richard, additional, Halciakova, Katarina, additional, Klokocnikova, Vera, additional, Kovar, Richard, additional, Lastuvka, Jiri, additional, Lukac, Martin, additional, Pesickova, Satu, additional, Peterka, Karel, additional, Pumprla, Jiri, additional, Rychlik, Ivan, additional, Saudek, Frantisek, additional, Tesar, Vladimir, additional, Valis, Martin, additional, Weiner, Pavel, additional, Zemek, Stanislav, additional, Alamartine, Eric, additional, Borot, Sophie, additional, Cariou, Bertrand, additional, Dussol, Bertrand, additional, Fauvel, Jean-Pierre, additional, Gourdy, Pierre, additional, Klein, Alexandre, additional, Le Meur, Yannick, additional, Penfornis, Alfred, additional, Roussel, Ronan, additional, Saulnier, Pierre-Jean, additional, Thervet, Eric, additional, Zaoui, Philippe, additional, Burst, Volker, additional, Faghih, Markus, additional, Faulmann, Grit, additional, Haller, Hermann, additional, Jerwan-Keim, Reinhold, additional, Maxeiner, Stephan, additional, Paschen, Björn, additional, Plassmann, Georg, additional, Rose, Ludger, additional, Gonzalez Orellana, Ronaldo Arturo, additional, Haase, Franklin Paul, additional, Moreira Diaz, Juan Pablo, additional, Ramirez Roca, Luis Alberto, additional, Sánchez Arenales, Jose Antonio, additional, Sanchez Polo, José Vicente, additional, Turcios Juarez, Erick, additional, Csecsei, Gyongyi, additional, Csiky, Botond, additional, Danos, Peter, additional, Deak, Laszlo, additional, Dudas, Mihaly, additional, Harcsa, Eleonora, additional, Keltai, Katalin, additional, Keresztesi, Sandor, additional, Kiss, Krisztian, additional, Konyves, Laszlo, additional, Major, Lajos, additional, Mileder, Margit, additional, Molnar, Marta, additional, Mucsi, Janos, additional, Oroszlan, Tamas, additional, Ory, Ivan, additional, Paragh, Gyorgy, additional, Peterfai, Eva, additional, Petro, Gizella, additional, Revesz, Katalin, additional, Takacs, Robert, additional, Vangel, Sandor, additional, Vasas, Szilard, additional, Zsom, Marianna, additional, Oomman, Abraham, additional, Raju, Sree Bhushan, additional, Dewan, Deepak, additional, Fernando, M. Edwin, additional, Gopalakrishnan, Natarajan, additional, Gracious, Noble, additional, Alva, Hansraj, additional, Jain, Dinesh, additional, Keshavamurthy, C. B., additional, Khullar, Dinesh, additional, Sahay, Manisha, additional, Peringat, Jayameena, additional, Prasad, Narayan, additional, Rao, K. Satyanarayana, additional, Reddy, Sreedhar, additional, Melemadathil, Sreelatha, additional, Sudhakar, Bhimavarapu, additional, Vyasam, Ramesh Chandra, additional, Bonadonna, Riccardo, additional, Castellino, Pietro, additional, Ceriello, Antonio, additional, Chiovato, Luca, additional, De Cosmo, Salvatore, additional, De Nicola, Luca, additional, Derosa, Giuseppe, additional, Di Carlo, Alberto, additional, Di Cianni, Graziano, additional, Frascà, Giovanni, additional, Fuiano, Giorgio, additional, Gambaro, Giovanni, additional, Garibotto, Giacomo, additional, Giorda, Carlo, additional, Malberti, Fabio, additional, Mandreoli, Marcora, additional, Mannucci, Edoardo, additional, Orsi, Emanuela, additional, Piatti, Piermarco, additional, Santoro, Domenico, additional, Sasso, Ferdinando Carlo, additional, Serviddio, Gaetano, additional, Stella, Andrea, additional, Trevisan, Roberto, additional, Veronelli, Anna Maria, additional, Zanoli, Luca, additional, Akiyama, Hitoshi, additional, Aoki, Hiromi, additional, Asano, Akimichi, additional, Iitsuka, Tadashi, additional, Kajiyama, Shizuo, additional, Kashine, Susumu, additional, Kawada, Toshio, additional, Kodera, Takamoto, additional, Kono, Hiroshi, additional, Koyama, Kazunori, additional, Kumeda, Yasuro, additional, Miyauchi, Shozo, additional, Mizuyama, Kazuyuki, additional, Niiya, Tetsuji, additional, Oishi, Hiroko, additional, Ota, Satoshi, additional, Sakakibara, Terue, additional, Takai, Masahiko, additional, Tomonaga, Osamu, additional, Tsujimoto, Mitsuru, additional, Wada, Takashi, additional, Wakasugi, Masakiyo, additional, Wakida, Yasushi, additional, Watanabe, Takayuki, additional, Yamada, Masayo, additional, Yanagida, Kazuhiro, additional, Yanase, Toshihiko, additional, Yumita, Wataru, additional, Gaupsiene, Egle, additional, Kozloviene, Dalia, additional, Navickas, Antanas, additional, Urbanaviciene, Egle, additional, Abdul Ghani, Rohana, additional, Abdul Kadir, Khalid, additional, Ali, Norsiah, additional, Che Yusof, Mohd Daud, additional, Gan, Chye Lee, additional, Ismail, Mastura, additional, Kong, Wei Yen, additional, Lam, Swee Win, additional, Lee, Li Yuan, additional, Lim, Soo Kun, additional, Loh, Chek Loong, additional, Manocha, Anita Bhajan, additional, Ng, Kee Sing, additional, Nik Ahmad, Nik Nur Fatnoon, additional, Ratnasingam, Vanassa, additional, Shudim, Saiful Shahrizal Bin, additional, Vengadasalam, Paranthaman, additional, Abraira Munoz, Luis David, additional, Alpizar Salazar, Melchor, additional, Baas Cruz, Juan, additional, Burgos Soto, Mario, additional, Chevaile Ramos, Jose, additional, Chew Wong, Alfredo, additional, Correa Rotter, Jose Ricardo, additional, Diaz Escalante, Tonatiu, additional, Enriquez Sosa, Favio Edmundo, additional, Flores Lozano, Fernando, additional, Flota Cervera, Luis Fernando, additional, Frenk Baron, Paul, additional, Garcia Ballesteros, Cecilia, additional, Gomez Rangel, Jose David, additional, Herrera Jimenez, Luis Enrique, additional, Irizar Santana, Sergio Saul, additional, Jimenez Flores, Fernando, additional, Laviada Molina, Hugo, additional, Luna Ceballos, Rosa Isela, additional, Martin del Campo Blanco, Belia, additional, Morales Franco, Guadalupe, additional, Moreno Loza, Oscar Tarsicio, additional, Mustieles Rocha, Cynthia, additional, Obrador Vera, Gregorio, additional, Orozco Castellanos, Ricardo, additional, Peralta Calcaneo, Juan, additional, Reyes Rosano, Miguel Angel, additional, Rodriguez Pattzi, Hiromi, additional, Rosas Guzman, Juan, additional, Rucker Joerg, Isabel Erika, additional, Saavedra Sanchez, Sandra Berenice, additional, Sanchez Mijangos, Jose Hector, additional, Serrano Sanson, Pablo, additional, Tamayo y Orozco, Juan Alfredo, additional, Tellez Chavez, Eloisa, additional, Valdes Cepeda, Alejandro, additional, Venegas Carrillo, Luis, additional, Villagordoa Mesa, Juan, additional, Zamarripa Escobedo, Rolando, additional, Baker, John, additional, Noonan, Paul, additional, Scott, Russell, additional, Walker, Robert, additional, Watson, Edward, additional, Williams, Michael, additional, Young, Simon, additional, Abejuela, Zaynab, additional, Agra, Jeimeen, additional, Aquitania, Grace, additional, Caringal, Clodoaido, additional, Comia, Rhea Severina, additional, Delos Santos, Lalaine, additional, Gomez, Olivert, additional, Jimeno, Cecilia, additional, Santos, Florence, additional, Tan, Gerry, additional, Tolentino, Marsha, additional, Yao, Christy, additional, Yap, Yvette Ethel, additional, Ygpuara, Ma. Dovie Lallaine, additional, Bijata-Bronisz, Renata, additional, Hotlos, Lucyna, additional, Januszewicz, Andrzej, additional, Kaczmarek, Barbara, additional, Kaminska, Anna, additional, Lazuka, Lech, additional, Madej, Andrzej, additional, Mazur, Stanislaw, additional, Mlodawska-Choluj, Dorota, additional, Nowicki, Michal, additional, Orlowska-Kowalik, Grazyna, additional, Popenda, Grazyna, additional, Rewerska, Barbara, additional, Sowinski, Dariusz, additional, Angelescu, Liliana Monica, additional, Anghel, Veronica, additional, Avram, Rodica-Ioana, additional, Busegeanu, Mihaela-Magdalena, additional, Cif, Adriana, additional, Cosma, Dana, additional, Crisan, Carmen, additional, Demian, Luiza Despina, additional, Ferariu, Ioana Emilia, additional, Halmagyi, Ildiko, additional, Hancu, Nicolae, additional, Munteanu, Mircea, additional, Negru, Doru, additional, Onaca, Adriana Gabriela, additional, Petrica, Ligia, additional, Popa, Amorin Remus, additional, Ranetti, Aurelian-Emil, additional, Serafinceanu, Cristian, additional, Toarba, Cristina, additional, Agafyina, Alina, additional, Barbarash, Olga, additional, Barysheva, Olga, additional, Chizhov, Daniil, additional, Dobronravov, Vladimir, additional, Dreval, Alexander, additional, Glinkina, Irina, additional, Grineva, Elena, additional, Khirmanov, Vladimir, additional, Kolmakova, Elena, additional, Koroleva, Tatiana, additional, Kvitkova, Liudmila, additional, Marasaev, Viacheslav, additional, Mkrtumyan, Ashot, additional, Morugova, Tatiana, additional, Nagibovich, Galina, additional, Nagibovich, Oleg, additional, Nedogoda, Sergei, additional, Osipova, Irina, additional, Raskina, Tatiana, additional, Samoylova, Yulia, additional, Sazonova, Olga, additional, Shamkhalova, Minara, additional, Shutemova, Elena, additional, Shwartz, Yuriy, additional, Uriasyev, Oleg, additional, Vorobyev, Sergey, additional, Zateyshchikova, Anna, additional, Zateyshshikov, Dmitry, additional, Zykova, Tatyana, additional, Antic, Slobodan, additional, Djordjevic, Miodrag, additional, Kendereski, Aleksandra, additional, Lalic, Katarina, additional, Lalic, Nebojsa, additional, Popovic-Radinovic, Vesna, additional, Babikova, Jana, additional, Benusova, Olga, additional, Buganova, Ingrid, additional, Culak, Jan, additional, Dzupina, Andrej, additional, Dzuponova, Jana, additional, Fulop, Peter, additional, Ilavska, Adriana, additional, Martinka, Emil, additional, Ochodnicka, Zuzana, additional, Pella, Daniel, additional, Smatanova, Iveta, additional, Ahmed, Fayzal, additional, Badat, Aysha, additional, Breedt, Johannes, additional, Distiller, Lawrence, additional, Govender, Vimladhevi, additional, Govender, Ravendran, additional, Joshi, Mukesh, additional, Jurgens, Jaco, additional, Latiff, Gulam, additional, Lombard, Landman, additional, Mookadam, Mohamed, additional, Ngcakani, Nomangesi, additional, Nortje, Hendrik, additional, Oosthuizen, Helena, additional, Pillay-Ramaya, Larisha, additional, Prozesky, Hans, additional, Reddy, Jeevren, additional, Rheeder, Paul, additional, Seeber, Mary, additional, Chae, Dong-Wan, additional, Cho, Young Min, additional, Jeong, In-Kyung, additional, Kim, Sin Gon, additional, Kim, Yeong Hoon, additional, Kwon, Hyuk-Sang, additional, Kwon, Min Jeong, additional, Lee, Byung-Wan, additional, Lee, JungEun, additional, Lee, Moon-Kyu, additional, Nam, Moon-Suk, additional, Oh, Kook-Hwan, additional, Park, Cheol-Young, additional, Park, Sun-Hee, additional, Yoon, Kun Ho, additional, Alvarez Garcia, Pere, additional, Asmarats Mercadal, Luis, additional, Barrios, Clara, additional, Cereto Castro, Fernando, additional, Cigarran Guldris, Secundino, additional, Dominguez Lopez, Marta, additional, Egido de los Rios, Jesus, additional, Fernandez Fresnedo, Gema, additional, Galan Serrano, Antonio, additional, Garcia, Isabel, additional, Gonzalez Martinez, Francisco Javier, additional, Jodar Gimeno, Jose Esteban, additional, Lopez Mendoza, Manuel, additional, Malek Marin, Tamara, additional, Morales Portillo, Cristobal, additional, Munar Vila, Maria Antonia, additional, Muñoz Torres, Manuel, additional, Nieto Iglesias, Javier, additional, Pantoja Perez, Jonay, additional, Perez Vera, Merce, additional, Portoles Perez, Jose Mª, additional, Quesada Simón, María Angustias, additional, Simo Canonge, Rafael, additional, Soto Gonzalez, Alfonso, additional, Terns Riera, Manel, additional, Tinahones Madueno, Francisco Jose, additional, Velo Plaza, Mercedes, additional, Chang, Chwen-Tzuei, additional, Chuang, Lee-Ming, additional, Hsia, Te-Lin, additional, Hsieh, Chang-Hsun, additional, Hwang, Shang-Jyh, additional, Lin, Chih-Ching, additional, Lu, Yung-Chuan, additional, Sheu, Wayne H-H, additional, Barna, Olga, additional, Bilyk, Svitlana D., additional, Botsyurko, Volodymyr, additional, Dudar, Iryna, additional, Fushtey, Ivan, additional, Godlevska, Olga, additional, Golovchenko, Oleksandr, additional, Gyrina, Olga, additional, Kazmirchuk, Anatoliy, additional, Kolesnyk, Mykola, additional, Komisarenko, Iuliia, additional, Korzh, Oleksii, additional, Kravchun, Nonna, additional, Legun, Oleg, additional, Mankovskyy, Borys, additional, Martynyuk, Liliya, additional, Mostovoy, Yuriy, additional, Pashkovska, Nataliia, additional, Pererva, Larysa, additional, Pertseva, Tetyana, additional, Samoylov, Oleksandr, additional, Smirnov, Ivan, additional, Svyshchenko, Yevgeniya, additional, Tomashkevych, Halyna, additional, Topchii, Ivan, additional, Tryshchuk, Nadiya, additional, Tseluyko, Vira, additional, Vizir, Vadym, additional, Vlasenko, Maryna, additional, Zlova, Tetiana, additional, Zub, Liliia, additional, Abusnana, Salah, additional, Railey, Mohamed, additional, Abouglila, Kamal, additional, Ainsworth, Paul, additional, Ali, Zishan, additional, Arutchelvam, Vijayaraman, additional, Barnard, Maria, additional, Bellary, Srikanth, additional, Davies, Emyr, additional, Davies, Mark, additional, Davies, Simon, additional, Dawson, Alison, additional, El Kossi, Mohsen, additional, English, Patrick, additional, Fraser, Donald, additional, Gnudi, Luigi, additional, Gunstone, Anthony, additional, Hall, Timothy, additional, Hanif, Wasim, additional, Jackson, Alan, additional, Johnson, Andrew, additional, Joseph, Franklin, additional, Krishnan, Singhan, additional, Kumwenda, Mick, additional, MacDougall, Iain, additional, Nixon, Paul, additional, O’Hare, Joseph, additional, Philip, Sam, additional, Ramtoola, Shenaz, additional, Saxena, Manish, additional, Sennik, Davesh, additional, Simon, Godwin, additional, Singh, Baldev, additional, Stephens, Jeffrey, additional, Strzelecka, Anna, additional, Symonds, Rehan, additional, Turner, Wayne, additional, Wahba, Mona, additional, Wakeling, John, additional, Wheeler, David, additional, Winocour, Peter, additional, Abdallah, Joseph, additional, Abdullah, Raied, additional, Abramowitz, Matthew, additional, Acosta, Idalia, additional, Aiello, Joseph, additional, Akright, Laura, additional, Akyea-Djamson, Ayim, additional, Alappan, Rajendran, additional, Alicic, Radica, additional, Al-Karadsheh, Amer, additional, Allison, Dale Crawford, additional, Arauz-Pacheco, Carlos, additional, Arfeen, Shahabul, additional, Arif, Ahmed, additional, Arvind, Moogali, additional, Atray, Naveen, additional, Awad, Ahmed, additional, Bakris, George, additional, Barnhill, Peggy, additional, Barranco, Elizabeth, additional, Barrera, Carlos, additional, Beacom, Matthew, additional, Behara, Venkata, additional, Belo, Diogo, additional, Bentley-Lewis, Rhonda, additional, Berenguer, Ramon, additional, Bermudez, Lidia, additional, Bernardo, Marializa, additional, Biscoveanu, Mihaela, additional, Bowman-Stroud, Cynthia, additional, Brandon, Donald, additional, Brusco, Osvaldo, additional, Busch, Robert, additional, Canaan, Yamil, additional, Chilito, Alicia, additional, Christensen, Tom, additional, Christiano, Cynthia, additional, Christofides, Elena, additional, Chuateco, Caroucel, additional, Cohen, Kenneth, additional, Cohen, Robert, additional, Cohen-Stein, Debbie, additional, Cook, Charles, additional, Coyne, Daniel, additional, Daboul, Nizar, additional, Darwish, Riad, additional, Daswani, Adarsh, additional, Deck, Kenneth, additional, Desouza, Cyrus, additional, Dev, Devasmita, additional, Dhillon, Monika, additional, Dua, Sohan, additional, Eder, Frank, additional, Elosegui, Ana Maria, additional, El-Shahawy, Mohamed, additional, Ervin, John, additional, Esquenazi, Alberto, additional, Evans, John, additional, Fishbane, Steven, additional, Frias, Juan, additional, Galindo-Ramos, Eugenia, additional, Galphin, Claude, additional, Ghazi, Adline, additional, Gonzalez, Enrique, additional, Gorson, David, additional, Gowda, Anupama, additional, Greco, Barbara, additional, Grubb, Stephen, additional, Gulati, Rakesh, additional, Hammoud, Jamal, additional, Handelsman, Stuart, additional, Hartman, Israel, additional, Hershon, Kenneth, additional, Hiser, Daniel, additional, Hon, George, additional, Jacob, Radu, additional, Jaime, Maria, additional, Jamal, Aamir, additional, Kaupke, Charles, additional, Keightley, Gerald, additional, Kern, Elizabeth, additional, Khanna, Rakhi, additional, Khitan, Zeid, additional, Kim, Sun, additional, Kopyt, Nelson, additional, Kovesdy, Csaba, additional, Krishna, Gopal, additional, Kropp, Jeffrey (Jay), additional, Kumar, Amrendra, additional, Kumar, Jayant, additional, Kumar, Neil, additional, Kusnir, Jorge, additional, Lane, Wendy, additional, Lawrence, Mary, additional, Lehrner, Lawrence, additional, Lentz, John, additional, Levinson, Dennis, additional, Lewis, Derek, additional, Liss, Kenneth, additional, Maddux, Andreas, additional, Maheshwari, Hiralal, additional, Mandayam, Sreedhar, additional, Marar, Isam, additional, Mehta, Bhasker, additional, Middleton, John, additional, Mordujovich, Jorge, additional, Moreda, Ramon, additional, Moustafa, Moustafa, additional, Mujica Trenche, Samuel, additional, Narayanan, Mohanram, additional, Narvarte, Javier, additional, Nassar, Tareq, additional, Newman, George, additional, Nichol, Brian, additional, Nicol, Philip, additional, Nisnisan, Josier, additional, Nossuli, A. Kaldun, additional, Obialo, Chamberlain, additional, Olelewe, Sarah, additional, Oliver, Michael, additional, O’Shaughnessy, Andrew, additional, Padron, John, additional, Pankhaniya, Rohit, additional, Parker, Reginald, additional, Patel, Devesh, additional, Patel, Gnyandev, additional, Patel, Nina, additional, Pavon, Humberto, additional, Perez, Armando, additional, Perez, Carlos, additional, Perlman, Alan, additional, Pettis, Karlton, additional, Pharr, Walter, additional, Phillips, Andrea, additional, Purighalla, Raman, additional, Quesada-Suarez, Luis, additional, Ranjan, Rajiv, additional, Rastogi, Sanjeev, additional, Reddy, Jakkidi, additional, Rendell, Marc, additional, Rich, Lisa, additional, Robinson, Michael, additional, Rodriguez, Hector, additional, Rosas, Sylvia, additional, Saba, Fadi, additional, Sankaram, Rallabhandi, additional, Sarin, Ravi, additional, Schreiman, Robert, additional, Scott, David, additional, Sekkarie, Mohamed, additional, Sensenbrenner, John, additional, Shakeel, Muhammad, additional, Shanik, Michael, additional, Shaw, Sylvia, additional, Smith, Stephen, additional, Solomon, Richard, additional, Sprague, Amy, additional, Spry, Leslie, additional, Suchinda, Pusadee, additional, Sultan, Senan, additional, Surampudi, Prasanth, additional, Sussman, Sherry, additional, Tan, Anjanette, additional, Terrelonge, Antonio, additional, Thompson, Michael, additional, Trespalacios, Fernando, additional, Trippe, Bruce, additional, Trueba, Pilar, additional, Twahirwa, Marcel, additional, Updegrove, John, additional, Van Buren, Peter, additional, Vannorsdall, Mark, additional, Varghese, Freemu, additional, Velasquez-Mieyer, Pedro, additional, Ventrapragada, Sailaja, additional, Vukotic, Goga, additional, Wadud, Khurram, additional, Warren, Mark, additional, Watson, Henry, additional, Watts, Ronald, additional, Weiner, Daniel, additional, Welker, James, additional, Welsh, Jean, additional, Williams, Shelley, additional, and Zaniewski-Singh, Michelle, additional

Published
2021
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15. MOESM2 of Translating recent results from the Cardiovascular Outcomes Trials into clinical practice: recommendations from the Central and Eastern European Diabetes Expert Group (CEEDEG)

Author

Schernthaner, Guntram, Lehmann, Roger, Prázný, Martin, Czupryniak, Leszek, Ducena, Kristine, Fasching, Peter, Janež, Andrej, Karasik, Avraham, Kempler, Peter, Martinka, Emil, Shestakova, Marina, Duvnjak, Lea, and Tsvetalina Tankova

Abstract

Additional file 2. Initial recommendation scoring.

Published
2017
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16. Ertugliflozin and Slope of Chronic eGFR

Author

Cherney, David Z.I., Cosentino, Francesco, Dagogo-Jack, Samuel, McGuire, Darren K., Pratley, Richard, Frederich, Robert, Maldonado, Mario, Liu, Chih-Chin, Liu, Jie, Pong, Annpey, Cannon, Christopher P., Pozzi, Jose Maria, Maffei, Laura, Nardone, Lucrecia, Sessa, Horacio, Brasca, Daniela Garcia, Aizenberg, Diego, Baccaro, Claudia Emilce, Gelersztein, Elizabeth Silvana, Rosario, Fabian Calella Pedro, Leon de la Fuente, Ricardo, de Lapertosa, Silvia Gorban, Maldonado, Natacha, Cruciani, Adrian, Bartolacci, Ines, Hasbani, Eduardo, Frechtel, Gustavo, Papini, Nelson Rodriguez, Pereyra, Alejandro, Montana, Oscar, Zaidman, Cesar, Mansilla, Maria, Ayres, Bronte, Simpson, Richard, Glastras, Sarah, William, Maged, Davis, Timothy, Colquhoun, David, Proietto, Joseph, Roberts, Adam, Roberts, Anthony, Stuckey, Bronwyn, Wittert, Gary, Soldatos, Georgia, Vora, Parind, Kusljugic, Zumreta, Avdagic, Azra, Durak-Nalbantic, Azra, Ibrahimpasic, Kanita, Horozic, Bosanko, Spuzic, Muhamed, Soldat-Stankovic, Valentina, Stevanovic, Dragan, Koco, Damir, Jatic, Zaim, Terzic, Ibrahim, Potkonjak, Ljiljana Markovic, Prnjavorac, Besim, Radanovic, Aleksandar, Salihbasic, Muhamed, Dimitrov, Dimitar, Stoikov, Anastas, Damyanova, Velichka, Vasileva, Darina, Kirilov, Kiril, Lefterov, Ivailo, Lyubenova, Lyudmila, Raev, Dimitar, Tsanova, Veska, Mitkov, Mitko, Shumkova, Rositsa, Kichukov, Kostadin, Simeonova-Nikolova, Tatyana, Ekoe, Jean-Marie, Pandey, Shekhar A., Dumas, Richard, Woo, Vincent, Saunders, Kevin, Conway, James, Breger, Laurie, Constance, Christian, O'Mahony, Michael, Perron, Patrice, Garceau, Claude, Csanadi, Michael, Bourgeois, Ronald, Salter, Timothy, Frechette, Andre, Diaz, Ariel, Ransom, Thomas, Sanchez-Vallejo, Gregorio, Silva, Sandra Isabel Barrera, Mendoza, Jose Accini, Ortiz, Luis Garcia, Lozno, Hernan Yupanqui, de Salazar, Dora Molina, Arroyo, Julian Coronel, Orozco Linares, Luis Alejandro, Lenis Rendon, Claudia Patricia, Darko, Pocanic, Tusek, Srecko, Weiss, Sonja Slosic, Silvija, Canecki-Varzic, Velimir, Altabas, Sidbela, Zukanovic, Cikac, Tatjana, Vucak, Jasna, Cenan, Ljiljana, Boljkovac, Zrinka, Margetic, Srecko, Kranjcevic, Ksenija, Cop, Renata, Adamkova, Vera, Pavlina, Kyselova, Wasserburger, Bedrich, Hrdina, Tomas, Smolenakova, Katerina, Ketevan, Chagunava, Pagava, Zurab, Mamatsashvili, Merab, Burnadze, Koba, Chumburidze, Vakhtang, Lominadze, Zaza, Nikoleishvili, Lali, Kobulia, Bondo, Koberidze, Nana, Emukhvari, Nodar, Kipiani, Zviad, Metreveli, David, Glonti, Salome, Giorgadze, Elene, Shaburishvili, Tamaz, Chapidze, Gulnara, Gulua, Julieta, Gogorishvili, Irakli, Berukashvili, Ekaterine, Petriashvili, Shalva, Kurashvili, Givi, Elisaf, Moses, Bousboulas, Stavros, Tentolouris, Nikolaos, Tsioufis, Konstantinos, Lymperi, Sotiria, Luk, Andrea, Yiu, Kelvin Kai Hang, Tsang, Chiu Chi, Yeung, Vincent Tok Fai, Lee, Alex Pui-Wai, Tan, Kathryn Choon Beng, Wan Ma, Ronald Ching, Wudi, Krisztina Beatrix, Bujtor, Zoltan, Feher, Zsuzsanna, Koranyi, Laszlo, Paragh, Gyorgy, Vasas, Szilard, Pauker, Zsolt, Kesmarki, Nora, Takacs, Janos, Nagy, Laszlo, Salamon, Csaba, Papp, Zsuzsanna, Hajdu, Csaba, Abramov, Galina, Hussein, Osamah, Vishlitzky, Victor, Dicker, Dror, Darawsha, Mahmud, Itzhak, Baruch, Gavish, Dov, Wainstein, Julio, Lewis, Basil, Klainman, Eliezer, Katz, Amos, Elias, Mazen, Ness-Abramof, Rosane, Hayek, Tony, Orsi, Emanuela, Lembo, Giuseppe, Piatti, Piermarco, Consoli, Agostino, Berti, Sergio, Pugliese, Giuseppe, Derosa, Giuseppe, Paolisso, Giuseppe, Limone, Paolo Piero, Jang, Hak Chul, Lee, Moon-Kyu, Kim, Nam Hoon, Cha, Bong-Soo, Park, Kyong Soo, Yoon, Kun Ho, Ahn, Chul Woo, Lee, Kwan Woo, Baik, Sei Hyun, Pirags, Valdis, Pastare, Sigita, Kavaliauskiene, Jurate, Augusteniene, Audrone, Navickas, Antanas, Urbanavicius, Vaidotas, Kavaliauskiene, Roma, Sirutaviciene, Ausra, Llamas Esperon, Guillermo Antonio, Mesa, Juan Villagordoa, Garcia Hernandez, Pedro Alberto, Ceballos, Rosa Luna, Salinas, Carlos Aguilar, Galvez, Guillermo Gonzalez, Melendez-Mier, Guillermo, Orozco, Raul Aguilar, Crijns, Harry, Hoogenberg, Klaas, Voors-Pette, Christine, Lunt, Helen, Scott, Russell, Baker, John, Williams, Michael, Kerr, Jane Elizabeth, Denopol, Marian, Panelo, Araceli, Tirador, Louie, Aquitania, Grace, Rogelio, Gregorio, Amorado-Santos, Florence, Habaluyas, Ramoncito, Rosa, Allyn Sy, Palomares, Ellen, Ebo, Geraldine, Romero, Chela Marie, Gladczak, Joanna, Hawryluk, Jaroslaw, Franek, Edward, Lukaszewicz, Monika, Madej-Dmochowska, Aleksandra, Jeznach-Steinhagen, Anna, Sokolowski, Grzegorz, Ruxer, Jan, Karczmarczyk, Agnieszka, Krzyzagorska, Ewa, Wozniak, Iwona, Olech-Cudzik, Anna, Dwojak, Marek, Anand, Izabela, Strojek, Krzysztof, Czernecka, Ewa, Antkowiak-Piatyszek, Karolina, Rozanska, Aleksandra, Gadzinski, Waldemar, Mader, Piotr, Kuligowska-jakubowska, Monika, Arciszewska, Malgorzata, Stankiewicz, Andrzej, Cypryk, Katarzyna, Wittek, Andrzej, Sawer-Szewczyk, Joanna, Pieniazek, Adam, Negrisanu, Gabriela, Pletea, Noemi, Zaharie, Daniela, Pintilei, Ella, Cif, Adriana, Duma, Livia, Szilagyi, Iosif, Halmagyi, Ildiko, Morosanu, Magdalena, Munteanu, Mircea, Albota, Adrian, Popescu, Alexandrina, Enculescu, Dan Anton, Hancu, Nicolae, Nafornita, Valerica, Croitoru, Lacramioara, Sebestyen, Lucia Luana, Pavlysh, Elena, Nikolaev, Konstantin, Vishnevsky, Alexandr, Reshetko, Olga, Kvitkova, Liudmila, Barbarash, Olga, Rodionova, Tatiana, Shaydyuk, Oxana, Ershova, Olga, Chizhov, Petr, Berns, Svetlana, Rechkova, Elena, Yakushin, Sergey, Zanozina, Olga, Lukyanov, Yuri, Vorobeva, Elena, Zateyshchikov, Dmitry, Verbovaya, Nelly, Bolshakova, Olga, Khrustalev, Oleg, Strongin, Leonid, Bondar, Irina, Zalevskaya, Alsu, Filippova, Ekaterina, Chumakova, Galina, Repin, Alexey, Panov, Alexey, Zivkovic, Teodora Beljic, Petakov, Milan, Sumarac-Dumanovic, Mirjana, Brankovic, Georgina Pudar, Kendereski, Aleksandra, Stojic, Stevo, Macut, Djuro, Babikova, Jana, Teplanova, Miriam, Tomasova, Livia, Martinka, Emil, Lachova, Beata, Ivancova, Gabriela, Rociakova, Jana, Schroner, Zbynek, Donicova, Viera, Ilavska, Adriana, Raslova, Katarina, Africa, South, Distiller, Lawrence, Siebert, Heidi, Badat, Aysha, Blignaut, Suzanne, Sarvan, Mahomed, Govender, Thirumani, Gani, Mashra, Nortje, Hendrik, Mookadam, Mohamed, Naiker, Puvanesveri, de Jong, Douwe, Van Zyl, Louis, Seeber, Mary, Urbach-Bolus, Dorothea, Bayat, Junaid, Boyd, Warren, du Toit, Margaretha, Punt, Zelda, Arnold, Susan, Van Dyk, Christo, Robertson, Leslie Ivan, Kotze, Hester Johanna, Anders, Luts, Martin, Lundvall, Carl-Johan, Lindholm, Bengt-Olov, Tengmark, Dan, Curiac, Peter, Bosson, Pekka, Koskinen, Hajimirsadeghi, Ali, Huang, Chen-Ling, Jiang, Ju-Ying, Hsia, Te- Lin, Ueng, Kwo-Chang, Yang, Wei-Shiung, Lu, Yung-Chuan, Yang, Chwen-Yi, Sheu, Wayne Huey-Herng, Chiang, Chern-En, Yeh, Hung-I, Suwanwalaikorn, Sompongse, Kosachunhanun, Natapong, Sritippayawan, Suchai, Tejavanija, Sirakarn, Silaruks, Songkwan, Araz, Mustafa, Sari, Ramazan, Berker, Dilek Sensoz, Arslan, Muyesser Sayki, Godlevska, Olga, Chopey, Ivan, Teliatnikova, Zinaida, Kuskalo, Petro, Abrahamovych, Orest, Mankovskyi, Borys, Fushtey, Ivan, Myshanych, Galyna, Tykhonova, Susanna, Tseluyko, Vira, Koval, Olena, Parkhomenko, Oleksandr, Prokhorov, Oleksandr, Vayda, Myroslava, Martymianova, Larysa, Zharinova, Viktoriia, Prystupa, Lyudmyla, Pererva, Larysa, Kovalov, Oleksandr, Sokolova, Lyubov, Botsyurko, Volodymyr, Maslyanko, Vitaliy, Vlasenko, Maryna, Khomazyuk, Tetyana, Kulyk, Anna, Synenko, Volodymyr, Karpenko, Oleksandr, Mostovoy, Yuriy, Gyrina, Olga, Dolzhenko, Maryna, Donets, Oleksandra, Sorokina, Inna, Malynovsky, Yaroslav, Lysunets, Olena, Petrovskyy, Roman, Panina, Svitlana, Avornyo, Anthony, Eyre, Susannah, Ryan, John, Cardwell, Glenn, Robinson, Anthony, Clark, Rebecca, Issa, Basil, Weeraratne, Devinda, McCrimmon, Rory, Jones, Thomas, Philip, Sam, Beboso, Ronnie, Davies, Melanie, Kyriakidou, Christina, Saxena, Manish, Thomas, Hawys, Gowda, Madhu, Arif, Imrozia, Oyesile, Babatunde, Cecil, John, Brunskill, Jonathan Mark Edwin, Akinboboye, Olakunle, Akright, Laura, Arora, Chander, Ball, Eric, Benjamin, Sabrina, Budoff, Matthew, Cathcart, Harold, Daboul, Nizar, Denker, Paul, Garner, Andrew, Jabbour, Serge, Jaffrani, Naseem, Jeanfreau, Robert, Knutson, Thomas, Lillestol, Michael, McNeil, Donald, Nakhle, Samer, Randall, William, Mallepalli, Jyothi, Schmidt, Jay, Serje, Jorge, Shoemaker, James, Storey, Daniel, Warner, Alberta, Pimentel, Severino, Quintero, Luis, Galvez, Juan, Bernard, David, Cruz, Humberto, O'Donnell, Philip, Thawani, Hemant, Sorial, Ehab, Schwartzbard, Arthur, Agaiby, John, Garcia, Bernard, Cone, Clancy, Doshi, Ankur, Iranmanesh, Ali, Lingvay, Ildiko, Smith, Kimberly, McLean, Barry, Neutel, Joel, Odugbesan, Adeniyi, Sligh, Teresa, Lesh, Kurt, Rohr, Kathryn, Ajani, Dilawar, Daniel, Jerome, Cornett, George, Dykstra, Gary, Mahal, Sharan, Adams, Michael, Ramstad, David, Arif, Ahmed, Martin, Earl, Sastre, Ramon, Srivastava, Sunny, Feld, Lawrence, Bush, Kelvin, Shah, Vinay, Konigsberg, Sarah, Allaw, Mohammed, Kelly, Richard, MacGillivray, Brian, McGuire, Michael, Weinstein, Debra, Budhraja, Madhusudan, Tahirkheli, Naeem, Binker, Josefa, Bernstein, Marc, Andrawis, Nabil, Abdullah, Shuaib, Christensen, Tom, Khan, Misal, El Shahawy, Mahfouz, Tripathy, Devjit, Ranadive, Nandkishore, Grena, Paul, Villafuerte, Betty, Cook, Charles, Bautista, Jose, Marar, Isam, Kaunzinger, Christian, Bittar, Neville, Frias, Juan, Davit, Rajesh, Bays, Harold, Cohen, Robert, Garvey, William, Smith, Stephen, Ruiz, Jose-Luis, Hartman, Aaron, Diener, James, Chochinov, Ronald, Hunter, John, Aronoff, Stephen, Reed, Larry, Evans, John, Ackermann, Jeremy, Haaksma, James, Torres-Consuegra, Aurelio, Khan, Jalil, Yousuf, Kabir, Bermudez, Lidia, Lumicao, Benjamin, Olmeda, Jorge Torres, Kessler, Evan, Winnie, Michael, Lending, Robert, Razzaque, Naveed, McCartney, Michael, Munoz, Francisco, Buynak, Robert, Ables, Lilia Rodriguez, Makam, Sashi, Lozano, Josefina, Paez, Henry, Gore, Ashwini, Al-Karadsheh, Amer, Masri, Bassem, Gorrela, Sushma, Al-Amin, Jessie Louise, Alani, Firas, Haffizulla, Jason, Hsieh, Ron, Hernandez, Luis Castillo, Turner, Merle, French, William, Jetty, Preetham, Sheikh-Ali, Mae, Leggett, Richard, Perlman, Richard, Goldstein, Gary, Osea, Edgardo A., Bartkowiak, Anthony James, Gimness, Michael Paul, Higgins, Alexander John, Khan, Sohail Mohyuddin, Rahimi, Ali R, Shah, Anil Vallabhdas, Lillo, Joseph Leonard, Hartman, Israel Alejandro, Whitney, Edwin J., Johnston, Janice G., Juarez, Mario R., Perley, Michael J., Kahn, Brian Howard, Amine, Maged A., Pace, Michael Anthony, Peters, Shirin Sabina, Hidalgo, Horacio Augusto, Krichmar, Perry, and Sinha, Rabi Ranjan

Published
2021
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18. Translating recent results from the Cardiovascular Outcomes Trials into clinical practice: recommendations from the Central and Eastern European Diabetes Expert Group (CEEDEG)

Author

Schernthaner, Guntram, Lehmann, Roger, Prázný, Martin, Czupryniak, Leszek, Ducena, Kristine, Fasching, Peter, Janež, Andrej, Karasik, Avraham, Kempler, Peter, Martinka, Emil, Shestakova, Marina V, Duvnjak, Lea Smirčić, Tankova, Tsvetalina, Schernthaner, Guntram, Lehmann, Roger, Prázný, Martin, Czupryniak, Leszek, Ducena, Kristine, Fasching, Peter, Janež, Andrej, Karasik, Avraham, Kempler, Peter, Martinka, Emil, Shestakova, Marina V, Duvnjak, Lea Smirčić, and Tankova, Tsvetalina

Abstract

AIMS These recommendations aim to improve care for patients with type 2 diabetes (T2D) at high cardiovascular (CV) risk in Central and Eastern Europe. Cardiovascular disease (CVD) and/or chronic kidney disease (CKD) are major interdependent comorbidities in patients with T2D, accounting for 50% of mortality. Following recent CV outcomes trial (CVOT) results, including those from EMPA-REG OUTCOME$^{®}$, LEADER$^{®}$, SUSTAIN™-6 and, most recently, the CANVAS study, it is essential to develop regional expert consensus recommendations to aid physicians in interpreting these newest data to clinical practice. METHODS The Central and Eastern European Diabetes Expert Group (CEEDEG) followed a Delphi method to develop treatment algorithms to aid physicians in the clinical management of patients with T2D at high CV risk. RESULTS In light of the latest CVOT results, and in particular the EMPA-REG OUTCOME$^{®}$ and LEADER$^{®}$ trials, the diagnosis, assessment, treatment choice and monitoring of patients with T2D and established CVD and/or CKD have been considered together with existing guidelines and presented in two reference algorithms. In addition, adherence, special prescribing considerations and a proposed multidisciplinary management approach have been discussed and are presented with the proposed algorithms. CONCLUSIONS The latest available high-level evidence on glucose-lowering drugs has enabled CEEDEG to develop practical consensus recommendations for patients with established CVD and/or CKD. These recommendations represent an update to international and country-level guidelines used for these patients, with the aim of providing a resource not only to endocrinologists, but to cardiologists, nephrologists and primary care physicians in the region.

Published
2017

19. Translating recent results from the Cardiovascular Outcomes Trials into clinical practice: recommendations from the Central and Eastern European Diabetes Expert Group (CEEDEG)

Author

Schernthaner, Guntram, primary, Lehmann, Roger, additional, Prázný, Martin, additional, Czupryniak, Leszek, additional, Ducena, Kristine, additional, Fasching, Peter, additional, Janež, Andrej, additional, Karasik, Avraham, additional, Kempler, Peter, additional, Martinka, Emil, additional, Shestakova, Marina V., additional, Duvnjak, Lea Smirčić, additional, and Tankova, Tsvetalina, additional

Published
2017
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21. Prevalence and epidemiological characteristics of patients with diabetic retinopathy in Slovakia: 12-month results from the DIARET SK study.

Author

Ondrejkova, Marta, Jackuliak, Peter, Martinka, Emil, Mokan, Marian, Foley, James, Fabkova, Jana, Gecik, Karol, Tvrda, Iveta, Helbich, Miroslav, and Gajdosova, Monika

Subjects
DIABETIC retinopathy, TYPE 1 diabetes, GLYCOSYLATED hemoglobin
Abstract

Purpose: To evaluate the prevalence and epidemiological characteristics of diabetic retinopathy (DR) in Slovakian patients with Type 1 and 2 diabetes mellitus (DM) in the DIARET SK study. Patients and methods: An epidemiological multi-center survey that included 4,078 adult patients (aged ≥18 years) from 51 diabetologists and 47 ophthalmologists. Data were collected from February to December 2015. Results: The final data set consisted of 4,014 patients; 3,700 were enrolled (Type 2 DM = 3,405, Type 1 DM = 295) using a quasi-random approach; 16 (Type 2 DM = 15, Type 1 DM = 1) patients in the pre-specified group had DM duration of <5 years with a history of DR while 298 patients (Type 2 DM = 204, Type 1 DM = 94) had DM duration of ≥ 20 years. The mean (standard deviation [SD]) age of patients at diagnosis for Types 2 and 1 DM was 53.4 (9.5) and 27.6 (12.9) years, respectively. The mean (SD) glycated hemoglobin (HbA1c) was 7.5 (1.4) and 8.5 (1.6) in Types 2 and 1 DM patients, respectively, whereas a slightly higher proportion of patients had >11.0 HbA1c in Type 1 DM (5.8%) than Type 2 (2.0%). The mean (SD) duration of Type 2 DM was shorter compared with Type 1 (7.5 [5.2] vs 10.3 [6.9] years). In Type 2 DM patients, there were 516 (15.5%) cases of DR, 19 (0.56%) of proliferative DR (PDR), and 106 (3.11%) of diabetic macular edema (DME). In Type 1 DM patients, there were 86 (29.15%) cases of DR, 10 (3.39%) PDR, and 12 (4.07%) DME. Conclusions: In Slovakian patients with DM, the duration of disease and higher HbA1c were the most prevalent factors that contributed to the development of DR and DME. [ABSTRACT FROM AUTHOR]

Published
2019
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23. An international, multicenter, observational survey to evaluate diabetes control in subjects using insulin for the treatment of type 1 and type 2 diabetes mellitus in the Czech Republic and Slovak Republic: study protocol for a cross-sectional survey

Author

Brož,Jan, Janickova Zdarska,Denisa, Urbanova,Jana, Brabec,Marek, Krivska,Bohumila, Donicova,Viera, Stepanova,Radka, Martinka,Emil, Kvapil,Milan, Brož,Jan, Janickova Zdarska,Denisa, Urbanova,Jana, Brabec,Marek, Krivska,Bohumila, Donicova,Viera, Stepanova,Radka, Martinka,Emil, and Kvapil,Milan

Abstract

Jan Brož,1 Denisa Janickova Zdarska,1 Jana Urbanova,2 Marek Brabec,3 Bohumila Krivska,4 Viera Donicova,5 Radka Stepanova,6 Emil Martinka,7 Milan Kvapil1 1Department of Internal Medicine, Second Faculty of Medicine, 2Center for Research on Diabetes, Metabolism and Nutrition, Second Department of Internal Medicine, Third Faculty of Medicine, Charles University, 3Institute of Computer Science of the ASCR, vvi, 4Sanofi, Prague, Czech Republic; 5Private Department of Diabetology, Internal Medicine and Metabolism, Kosice, Slovak Republic; 6ADDS sro, Brno, Czech Republic; 7National Institute of Endocrinology and Diabetology, Lubochna, Slovak Republic Background: Despite the improvements in insulin therapy, a large number of patients fail to achieve their target glycated hemoglobin (HbA1c) levels. Control of diabetes is often unsatisfactory because the patient does not know about the principles of successful insulin therapy (ie, blood glucose self-monitoring, the principles of insulin administration, titration, current dose adjustments, dietary recommendations, and physical activity preventive measures) or because these principles are applied incorrectly or insufficiently. Furthermore, the fear of hypoglycemia may lead to maintaining higher than recommended blood glucose levels. Methods/design: This is a noninterventional, international study focusing on a questionnaire survey of diabetes patients (patient-reported outcome) treated with insulin for at least 1 year. It is designed so that the data obtained reflect real access of patients to insulin treatment. The primary objective is to show the results of glycemic control of diabetes (HbA1c) achieved in diabetes patients treated with at least one dose of insulin. The secondary objective is to monitor the factors potentially affecting these results, which include the frequency and other characteristics of hypoglycemia, the frequency of blood glucose self-monitoring, and the effects produced when the results are employed in

Published
2016

24. An international, multicenter, observational survey to evaluate diabetes control in subjects using insulin for the treatment of type 1 and type 2 diabetes mellitus in the Czech Republic and Slovak Republic: study protocol for a cross-sectional survey

Author

Brož, Jan, primary, Janickova Zdarska, Denisa, additional, Urbanova, Jana, additional, Brabec, Marek, additional, Krivska, Bohumila, additional, Donicova, Viera, additional, Stepanova, Radka, additional, Martinka, Emil, additional, and Kvapil, Milan, additional

Published
2016
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27. Self-Monitoring of Blood Glucose in Diabetes: From Evidence to Clinical Reality in Central and Eastern Europe—Recommendations from the International Central-Eastern European Expert Group

Author

Czupryniak, Leszek, primary, Barkai, László, additional, Bolgarska, Svetlana, additional, Bronisz, Agata, additional, Broz, Jan, additional, Cypryk, Katarzyna, additional, Honka, Marek, additional, Janez, Andrej, additional, Krnic, Mladen, additional, Lalic, Nebojsa, additional, Martinka, Emil, additional, Rahelic, Dario, additional, Roman, Gabriela, additional, Tankova, Tsvetalina, additional, Várkonyi, Tamás, additional, Wolnik, Bogumił, additional, and Zherdova, Nadia, additional

Published
2014
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28. Kidney and Cardiovascular Effects of Canagliflozin According to Age and Sex: A Post Hoc Analysis of the CREDENCE Randomized Clinical Trial

Author

Yi, Tae Won, Smyth, Brendan, Di Tanna, Gian Luca, Arnott, Clare, Cardoza, Kathryn, Kang, Amy, Pollock, Carol, Agarwal, Rajiv, Bakris, George, Charytan, David M., de Zeeuw, Dick, Heerspink, Hiddo J.L., Neal, Bruce, Wheeler, David C., Cannon, Christopher P., Zhang, Hong, Zinman, Bernard, Perkovic, Vlado, Levin, Adeera, Mahaffey, Kenneth W., Jardine, Meg, Perkovic, Vlado, Mahaffey, Kenneth W., Agarwal, Rajiv, Bakris, George, Brenner, Barry M., Cannon, Christopher P., Charytan, David M., de Zeeuw, Dick, Greene, Tom, Jardine, Meg J., Heerspink, Hiddo J.L., Levin, Adeera, Meininger, Gary, Neal, Bruce, Pollock, Carol, Wheeler, David C., Zhang, Hong, Zinman, Bernard, Jardine, Meg, Heerspink, Hiddo J.L., Charytan, David M., Li, Nicole, Kolesnyk, Inna, Aizenberg, Diego, Pecoits-Filho, Roberto, Levin, Adeera, Cherney, David, Obrador, Gregorio, Chertow, Glenn, Chang, Tara, Hawley, Carmel, Ji, Linong, Zhang, Hong, Wada, Takashi, Jha, Vivekanand, Lim, Soo Kun, Lim-Abrahan, Mary Anne, Santos, Florence, Chae, Dong-Wan, Hwang, Shang-Jyh, Vazelov, Evgueniy, Rychlík, Ivan, Hadjadj, Samy, Krane, Vera, Rosivall, László, De Nicola, Luca, Dreval, Alexander, Nowicki, Michał, Schiller, Adalbert, Distiller, Larry, Górriz, Jose L., Kolesnyk, Mykola, David, Wheeler, C., Guerrero, Rodolfo Andres Ahuad, Aizenberg, Diego, Albisu, Juan Pablo, Alvarisqueta, Andres, Bartolacci, Ines, Berli, Mario Alberto, Bordonava, Anselmo, Calella, Pedro, Cantero, Maria Cecilia, Cartasegna, Luis Rodolfo, Cercos, Esteban, Coloma, Gabriela Cecilia, Colombo, Hugo, Commendatore, Victor, Cuadrado, Jesus, Cuneo, Carlos Alberto, Cusumano, Ana Maria, Douthat, Walter Guillermo, Dran, Ricardo Dario, Farias, Eduardo, Fernandez, Maria Florencia, Finkelstein, Hernan, Fragale, Guillermo, Fretes, Jose Osvaldo, Garcia, Nestor Horacio, Gastaldi, Anibal, Gelersztein, Elizabeth, Glenny, Jorge Archibaldo, Gonzalez, Joaquin Pablo, Colaso, Patricia del Carmen Gonzalez, Goycoa, Claudia, Greloni, Gustavo Cristian, Guinsburg, Adrian, Hermida, Sonia, Juncos, Luis Isaias, Klyver, Maria Isabel, Kraft, Florencia, Krynski, Fernando, Lanchiotti, Paulina Virginia, Leon de la Fuente, Ricardo Alfonso, Marchetta, Nora, Mele, Pablo, Nicolai, Silvia, Novoa, Pablo Antonio, Orio, Silvia Ines, Otreras, Fabian, Oviedo, Alejandra, Raffaele, Pablo, Resk, Jorge Hector, Rista, Lucas, Papini, Nelson Rodriguez, Sala, Jorgelina, Santos, Juan Carlos, Schiavi, Lilia Beatriz, Sessa, Horacio, Casabella, Tomas Smith, Ulla, Maria Rosa, Valdez, Maria, Vallejos, Augusto, Villarino, Adriana, Visco, Virginia Esther, Wassermann, Alfredo, Zaidman, Cesar Javier, Cheung, Ngai Wah, Droste, Carolyn, Fraser, Ian, Johnson, David, Mah, Peak Mann, Nicholls, Kathy, Packham, David, Proietto, Joseph, Roberts, Anthony, Roger, Simon, Tsang, Venessa, Raduan, Roberto Abrão, Costa, Fernando Augusto Alves da, Amodeo, Celso, Turatti, Luiz Alberto Andreotti, Bregman, Rachel, Sanches, Fernanda Cristina Camelo, Canani, Luis Henrique, Chacra, Antônio Roberto, Borges, João Lindolfo Cunha, Vêncio, Sérgio Alberto Cunha, Franco, Roberto Jorge da Silva, d’Avila, Domingos, Portes, Evandro de Souza, de Souza, Pedro, Deboni, Luciane Mônica, Fraige Filho, Fadlo, Neto, Bruno Geloneze, Gomes, Marcus, Kohara, Suely Keiko, Keitel, Elizete, Saraiva, Jose Francisco Kerr, Lisboa, Hugo Roberto Kurtz, Contieri, Fabiana Loss de Carvalho, Milagres, Rosângela, Junior, Renan Montenegro, de Brito, Claudia Moreira, Hissa, Miguel Nasser, Sabbag, Ângela Regina Nazario, Noronha, Irene, Panarotto, Daniel, Filho, Roberto Pecoits, Pereira, Márcio Antônio, Saporito, Wladmir, Scotton, Antonio Scafuto, Schuch, Tiago, de Almeida, Roberto Simões, Ramos, Cássio Slompo, Felício, João Soares, Thomé, Fernando, Hachmann, Jean Carlo Tibes, Yamada, Sérgio, Hayashida, Cesar Yoiti, Petry, Tarissa Beatrice Zanata, Zanella, Maria Teresa, Andreeva, Viktoria, Angelova, Angelina, Dimitrov, Stefan, Genadieva, Veselka, Genova-Hristova, Gabriela, Hristozov, Kiril, Kamenov, Zdravko, 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Cyrus, Dev, Devasmita, Dhillon, Monika, Dua, Sohan, Eder, Frank, Elosegui, Ana Maria, El-Shahawy, Mohamed, Ervin, John, Esquenazi, Alberto, Evans, John, Fishbane, Steven, Frias, Juan, Galindo-Ramos, Eugenia, Galphin, Claude, Ghazi, Adline, Gonzalez, Enrique, Gorson, David, Gowda, Anupama, Greco, Barbara, Grubb, Stephen, Gulati, Rakesh, Hammoud, Jamal, Handelsman, Stuart, Hartman, Israel, Hershon, Kenneth, Hiser, Daniel, Hon, George, Jacob, Radu, Jaime, Maria, Jamal, Aamir, Kaupke, Charles, Keightley, Gerald, Kern, Elizabeth, Khanna, Rakhi, Khitan, Zeid, Kim, Sun, Kopyt, Nelson, Kovesdy, Csaba, Krishna, Gopal, Kropp, Jeffrey (Jay), Kumar, Amrendra, Kumar, Jayant, Kumar, Neil, Kusnir, Jorge, Lane, Wendy, Lawrence, Mary, Lehrner, Lawrence, Lentz, John, Levinson, Dennis, Lewis, Derek, Liss, Kenneth, Maddux, Andreas, Maheshwari, Hiralal, Mandayam, Sreedhar, Marar, Isam, Mehta, Bhasker, Middleton, John, Mordujovich, Jorge, Moreda, Ramon, Moustafa, Moustafa, Trenche, Samuel Mujica, Narayanan, Mohanram, Narvarte, Javier, Nassar, Tareq, Newman, George, Nichol, Brian, Nicol, Philip, Nisnisan, Josier, Nossuli, A. Kaldun, Obialo, Chamberlain, Olelewe, Sarah, Oliver, Michael, O'Shaughnessy, Andrew, Padron, John, Pankhaniya, Rohit, Parker, Reginald, Patel, Devesh, Patel, Gnyandev, Patel, Nina, Pavon, Humberto, Perez, Armando, Perez, Carlos, Perlman, Alan, Pettis, Karlton, Pharr, Walter, Phillips, Andrea, Purighalla, Raman, Quesada-Suarez, Luis, Ranjan, Rajiv, Rastogi, Sanjeev, Reddy, Jakkidi, Rendell, Marc, Rich, Lisa, Robinson, Michael, Rodriguez, Hector, Rosas, Sylvia, Saba, Fadi, Sankaram, Rallabhandi, Sarin, Ravi, Schreiman, Robert, Scott, David, Sekkarie, Mohamed, Sensenbrenner, John, Shakeel, Muhammad, Shanik, Michael, Shaw, Sylvia, Smith, Stephen, Solomon, Richard, Sprague, Amy, Spry, Leslie, Suchinda, Pusadee, Sultan, Senan, Surampudi, Prasanth, Sussman, Sherry, Tan, Anjanette, Terrelonge, Antonio, Thompson, Michael, Trespalacios, Fernando, Trippe, Bruce, Trueba, Pilar, Twahirwa, Marcel, Updegrove, John, Van Buren, Peter, Vannorsdall, Mark, Varghese, Freemu, Velasquez-Mieyer, Pedro, Ventrapragada, Sailaja, Vukotic, Goga, Wadud, Khurram, Warren, Mark, Watson, Henry, Watts, Ronald, Weiner, Daniel, Welker, James, Welsh, Jean, Williams, Shelley, and Zaniewski-Singh, Michelle

Abstract

It is unclear whether the effect of canagliflozin on adverse kidney and cardiovascular events in those with diabetic kidney disease varies by age and sex. We assessed the effects of canagliflozin among age group categories and between sexes in the Canagliflozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) study.

Published
2023
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34. SGLT2 inhibitors in T2D and associated comorbidities - differentiating within the class

Author

Schernthaner, Guntram, Drexel, Heinz, Moshkovich, Evgeny, Zilaitiene, Birute, Martinka, Emil, Czupryniak, Leszek, Várkonyi, Tamás, Janež, Andrej, Ducena, Kristine, Lalić, Katarina, Tankova, Tsvetalina, Prázný, Martin, Smirčić Duvnjak, Lea, Sukhareva, Olga, and Sourij, Harald

Subjects
610 Medicine & health, 3. Good health
Abstract

BACKGROUND For patients with type 2 diabetes (T2D), cardiovascular disease (CVD) is the single most common cause of mortality. In 2008 and 2012, the Federal Drug Administration (FDA) and the European Medicines Agency (EMA) respectively mandated cardiovascular outcomes trials (CVOTs) on all new anti-diabetic agents, as prospective trials statistically powered to rule out excess cardiovascular risk in patients with T2D. Unexpectedly, some of these CVOTs have demonstrated not only cardiovascular safety, but also cardioprotective effects, as was first shown for the SGLT2 inhibitor empagliflozin in EMPA-REG OUTCOME. EXPERT OPINION To debate newly available CVOT data and to put them into context, we convened as a group of medical experts from the Central and Eastern European Region. Here we describe our discussions, focusing on the conclusions we can draw from EMPA-REG OUTCOME and other SGLT2 inhibitor CVOTs, including when considered alongside real-world evidence. CONCLUSION CVOTs investigating SGLT2 inhibitors have suggested benefits beyond glucose lowering that have been confirmed in real-world evidence studies.

37. [Autoimmune insulitis in patients with type 2 diabetes mellitus A randomized clinical trial in hospitalized patients].

Author

Martinka E, Rončáková M, Mišániková M, and Davani A

Subjects
Adult, Aged, Autoantibodies blood, C-Peptide blood, Cholesterol, HDL blood, Diabetes Mellitus, Type 1 drug therapy, Diabetes Mellitus, Type 2 blood, Diabetes Mellitus, Type 2 drug therapy, Female, Glutamate Decarboxylase blood, Hospitalization, Humans, Hypoglycemia drug therapy, Hypoglycemia epidemiology, Hypoglycemic Agents therapeutic use, Insulin therapeutic use, Insulin Resistance physiology, Male, Middle Aged, Thyroid Diseases epidemiology, Waist Circumference, Diabetes Mellitus, Type 1 epidemiology, Diabetes Mellitus, Type 2 immunology
Abstract

Background: It is not always easy to classify diabetes (DM) diagnosed in adults, with a significant group of patients initially classified and treated for type 2 diabetes mellitus (DM2T) presenting signs indicating the presence of autoimmune insulitis (AI), which is characteristic of type 1 diabetes mellitus (DM1T), or latent autoimmune diabetes mellitus in adults (LADA)., Goal: Identify the proportion of patients entered with DM2T who present AI signs, and the number of patients of that proportion, who at the same time present low insulin secretion, and what clinical and laboratory manifestations could be used to differentiate between these patients.Cohort and methods: A randomized clinical trial with a pre-determined set of assessed parameters for n = 625 patients, who were hospitalized during the first 6 months of 2016 at the National Endocrinology and Diabetology Institute (NEDU), Lubochna. Apart from the standard parameters, C-peptide (CP) and autoantibodies to glutamic acid decarboxylase (GADA) were examined for each patient. GADA positive (GADA+) patients were compared to GADA negative (GADA-) patients in the following parameters: gender, age, age at the time of dia-gnosing DM, duration of DM, HbA1c, incidence of hypoglycemia, lipidogram, fasting C-peptide levels, BMI, waist circumference, incidence of hypoglycemias, presence of microvascular and macrovascular complications, treatment of dia-betes and incidence of other endocrinopathies. GADA+ with low CP were subsequently compared to GADA+ patients with normal CP., Results: Of 625 patients originally classified and treated as DM2T, 13 % were GADA+. 31 % of them had low CP (< 0.2 nmol/l) and 28 % had CP levels within the intermediary range (0.2-0.4 nmol/l). Females made up a larger proportion of GADA+ patients, with a lower BMI, smaller waist circumference, lower CP, higher HDL cholesterol levels, a greater incidence of hypoglycemias and lower total daily dose of insulin. GADA+ patients with low CP differed from GADA+ patients with normal CP in higher HDL cholesterol levels, lower triglyceride levels and earlier need of insulin thera-py. The testing for GADA and CP levels with regard to the other relevant characteristics led to re-classification, or more precisely adding of DM1T/LADA (as the main, or parallel cause of DM) for 2.9 % of all the patients included and a clinically significant proportion of AI could be assumed in 6.1 % of the patients., Summary: The results of our study show that the pathogenesis of DM in patients initially diagnosed and registered with DM2T and with concurrent presence of GADA includes mechanisms characteristic of both DM2T (insulin resistance) and DM1T (autoimmune insulitis) acting in parallel, with different intensity, in differing proportions and time sequence as a fluid continuum, which also accounts for the differences between individual patients. The characteristics highlighting the presence and role of AI based on our results include high titre of GADA+, low CP levels, early need of insulin therapy, presence of thyroid disorder, higher HDL cholesterol levels and lower triglyceride levels. The characteristics highlighting the dominance of mechanisms characteristic of DM2T (insulin resistance) included higher BMI and waist circumference values, normal CP levels, low HDL cholesterol levels, higher triglyceride levels, higher blood pressure and borderline titre of GADA., Key Words: autoimmune diabetes mellitus - C-peptide - GADA - HDL-cholesterol - classification.

Published
2016

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