1,891 results on '"Martin-Loeches Ignacio"'
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2. Environmental sustainability in intensive care: the path forward. An ESICM Green Paper
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De Waele, Jan J., Hunfeld, Nicole, Baid, Heather, Ferrer, Ricard, Iliopoulou, Katerina, Ioan, Ana-Maria, Leone, Marc, Ostermann, Marlies, Scaramuzzo, Gaetano, Theodorakopoulou, Maria, Touw, Hugo, Citerio, Giuseppe, Derde, Lennie P. G., Donadello, Katia, Juffermans, Nicole P., Galarza, Laura, Grasselli, Giacomo, Maggiore, Salvatore Maurizio, Martin-Loeches, Ignacio, Alexandre, Joel, Cecconi, Maurizio, and Azoulay, Elie
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- 2024
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3. Understanding, assessing and treating immune, endothelial and haemostasis dysfunctions in bacterial sepsis
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Girardis, Massimo, David, Sascha, Ferrer, Ricard, Helms, Julie, Juffermans, Nicole P., Martin-Loeches, Ignacio, Povoa, Pedro, Russell, Lene, Shankar-Hari, Manu, Iba, Toshiaki, Coloretti, Irene, Parchim, Nicholas, and Nielsen, Nathan D.
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- 2024
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4. Major alteration of lung microbiome and the host responses in critically ill COVID-19 patients with high viral load
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Bustos, Ingrid G., Wiscovitch-Russo, Rosana, Singh, Harinder, Sievers, Benjamín L., Matsuoka, Michele, Freire, Marcelo, Tan, Gene S., Cala, Mónica P., Guerrero, Jose L., Martin-Loeches, Ignacio, Gonzalez-Juarbe, Norberto, and Reyes, Luis Felipe
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- 2024
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5. Epidemiology, ventilation management and outcomes of COVID–19 ARDS patients versus patients with ARDS due to pneumonia in the Pre–COVID era
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van der Ven, Fleur–Stefanie L. I. M., Blok, Siebe G., Azevedo, Luciano C., Bellani, Giacomo, Botta, Michela, Estenssoro, Elisa, Fan, Eddy, Ferreira, Juliana Carvalho, Laffey, John G., Martin–Loeches, Ignacio, Motos, Ana, Pham, Tai, Peñuelas, Oscar, Pesenti, Antonio, Pisani, Luigi, Neto, Ary Serpa, Schultz, Marcus J., Torres, Antoni, Tsonas, Anissa M., Paulus, Frederique, and van Meenen, David M. P.
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- 2024
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6. Interpretation of results of PCR and B-D-glucan for the diagnosis of Pneumocystis Jirovecii Pneumonia in immunocompromised adults with acute respiratory failure
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Calvet, Laure, Lemiale, Virginie, Mokart, Djamel, Peter, Schellongowski, Peter, Pickkers, Demoule, Alexande, Mehta, Sangeeta, Kouatchet, Achille, Rello, Jordi, Bauer, Philippe, Martin-Loeches, Ignacio, Seguin, Amelie, Metaxa, Victoria, Bisbal, Magali, Azoulay, Elie, and Darmon, Michael
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- 2024
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7. Biomarkers in pulmonary infections: a clinical approach
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Póvoa, Pedro, Coelho, Luís, Cidade, José Pedro, Ceccato, Adrian, Morris, Andrew Conway, Salluh, Jorge, Nobre, Vandack, Nseir, Saad, Martin-Loeches, Ignacio, Lisboa, Thiago, Ramirez, Paula, Rouzé, Anahita, Sweeney, Daniel A., and Kalil, Andre C.
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- 2024
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8. A targeted likelihood estimation comparing cefepime and piperacillin/tazobactam in critically ill patients with community-acquired pneumonia (CAP)
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Serrano-Mayorga, Cristian C., Duque, Sara, Ibáñez-Prada, Elsa D., Garcia-Gallo, Esteban, Arrieta, María P. Rojas, Bastidas, Alirio, Rodríguez, Alejandro, Martin-Loeches, Ignacio, and Reyes, Luis F.
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- 2024
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9. Intra-abdominal infections survival guide: a position statement by the Global Alliance For Infections In Surgery
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Sartelli, Massimo, Barie, Philip, Agnoletti, Vanni, Al-Hasan, Majdi N., Ansaloni, Luca, Biffl, Walter, Buonomo, Luis, Blot, Stijn, Cheadle, William G., Coimbra, Raul, De Simone, Belinda, Duane, Therese M., Fugazzola, Paola, Giamarellou, Helen, Hardcastle, Timothy C., Hecker, Andreas, Inaba, Kenji, Kirkpatrick, Andrew W., Labricciosa, Francesco M., Leone, Marc, Martin-Loeches, Ignacio, Maier, Ronald V., Marwah, Sanjay, Maves, Ryan C., Mingoli, Andrea, Montravers, Philippe, Ordóñez, Carlos A., Palmieri, Miriam, Podda, Mauro, Rello, Jordi, Sawyer, Robert G., Sganga, Gabriele, Tattevin, Pierre, Thapaliya, Dipendra, Tessier, Jeffrey, Tolonen, Matti, Ulrych, Jan, Vallicelli, Carlo, Watkins, Richard R., Catena, Fausto, and Coccolini, Federico
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- 2024
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10. An international RAND/UCLA expert panel to determine the optimal diagnosis and management of burn inhalation injury.
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Milton-Jones, Helena, Soussi, Sabri, Davies, Roger, Charbonney, Emmanuel, Charles, Walton, Cleland, Heather, Dunn, Ken, Gantner, Dashiell, Giles, Julian, Jeschke, Marc, Lee, Nicole, Legrand, Matthieu, Lloyd, Joanne, Martin-Loeches, Ignacio, Pantet, Olivier, Samaan, Mark, Shelley, Odhran, Sisson, Alice, Spragg, Kaisa, Wood, Fiona, Yarrow, Jeremy, Vizcaychipi, Marcela, Williams, Andrew, Leon-Villapalos, Jorge, Collins, Declan, Jones, Isabel, and Singh, Suveer
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Acute lung injury ,Acute respiratory distress syndrome ,Bronchoscopy ,Burn inhalation injury ,Burns ,Endotracheal intubation ,Heparin ,Mechanical ventilation ,Smoke inhalation injury ,Humans ,Acetylcysteine ,Burns ,Respiration ,Artificial ,Heparin ,Lung Injury ,Albuterol - Abstract
BACKGROUND: Burn inhalation injury (BII) is a major cause of burn-related mortality and morbidity. Despite published practice guidelines, no consensus exists for the best strategies regarding diagnosis and management of BII. A modified DELPHI study using the RAND/UCLA (University of California, Los Angeles) Appropriateness Method (RAM) systematically analysed the opinions of an expert panel. Expert opinion was combined with available evidence to determine what constitutes appropriate and inappropriate judgement in the diagnosis and management of BII. METHODS: A 15-person multidisciplinary panel comprised anaesthetists, intensivists and plastic surgeons involved in the clinical management of major burn patients adopted a modified Delphi approach using the RAM method. They rated the appropriateness of statements describing diagnostic and management options for BII on a Likert scale. A modified final survey comprising 140 statements was completed, subdivided into history and physical examination (20), investigations (39), airway management (5), systemic toxicity (23), invasive mechanical ventilation (29) and pharmacotherapy (24). Median appropriateness ratings and the disagreement index (DI) were calculated to classify statements as appropriate, uncertain, or inappropriate. RESULTS: Of 140 statements, 74 were rated as appropriate, 40 as uncertain and 26 as inappropriate. Initial intubation with ≥ 8.0 mm endotracheal tubes, lung protective ventilatory strategies, initial bronchoscopic lavage, serial bronchoscopic lavage for severe BII, nebulised heparin and salbutamol administration for moderate-severe BII and N-acetylcysteine for moderate BII were rated appropriate. Non-protective ventilatory strategies, high-frequency oscillatory ventilation, high-frequency percussive ventilation, prophylactic systemic antibiotics and corticosteroids were rated inappropriate. Experts disagreed (DI ≥ 1) on six statements, classified uncertain: the use of flexible fiberoptic bronchoscopy to guide fluid requirements (DI = 1.52), intubation with endotracheal tubes of internal diameter
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- 2023
11. Challenges for a broad international implementation of the current severe community-acquired pneumonia guidelines
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Salluh, Jorge I. F., Póvoa, Pedro, Beane, Abi, Kalil, Andre, Sendagire, Cornelius, Sweeney, Daniel A., Pilcher, David, Polverino, Eva, Tacconelli, Evelina, Estenssoro, Elisa, Frat, Jean-Pierre, Ramirez, Julio, Reyes, Luis Felipe, Roca, Oriol, Nseir, Saad, Nobre, Vandack, Lisboa, Thiago, and Martin-Loeches, Ignacio
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- 2024
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12. Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM
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Bassetti, Matteo, Giacobbe, Daniele R., Agvald-Ohman, Christina, Akova, Murat, Alastruey-Izquierdo, Ana, Arikan-Akdagli, Sevtap, Azoulay, Elie, Blot, Stijn, Cornely, Oliver A., Cuenca-Estrella, Manuel, de Lange, Dylan W., De Rosa, Francesco G., De Waele, Jan J., Dimopoulos, George, Garnacho-Montero, Jose, Hoenigl, Martin, Kanj, Souha S., Koehler, Philipp, Kullberg, Bart J., Lamoth, Frédéric, Lass-Flörl, Cornelia, Maertens, Johan, Martin-Loeches, Ignacio, Muñoz, Patricia, Poulakou, Garyphallia, Rello, Jordi, Sanguinetti, Maurizio, Taccone, Fabio S., Timsit, Jean-François, Torres, Antoni, Vazquez, Jose A., Wauters, Joost, Asperges, Erika, Cortegiani, Andrea, Grecchi, Cecilia, Karaiskos, Ilias, Le Bihan, Clément, Mercier, Toine, Mortensen, Klaus L., Peghin, Maddalena, Rebuffi, Chiara, Tejada, Sofia, Vena, Antonio, Zuccaro, Valentina, Scudeller, Luigia, and Calandra, Thierry
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- 2024
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13. ICU-acquired infections in immunocompromised patients
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Kreitmann, Louis, Helms, Julie, Martin-Loeches, Ignacio, Salluh, Jorge, Poulakou, Garyphallia, Pène, Frédéric, and Nseir, Saad
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- 2024
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14. Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment
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Greene, Chris, Connolly, Ruairi, Brennan, Declan, Laffan, Aoife, O’Keeffe, Eoin, Zaporojan, Lilia, O’Callaghan, Jeffrey, Thomson, Bennett, Connolly, Emma, Argue, Ruth, Meaney, James F. M., Martin-Loeches, Ignacio, Long, Aideen, Cheallaigh, Cliona Ni, Conlon, Niall, Doherty, Colin P., and Campbell, Matthew
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- 2024
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15. Stroke in critically ill patients with respiratory failure due to COVID-19: Disparities between low-middle and high-income countries
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Al-Dabbous, Tala, Alfoudri, Huda, Shamsah, Mohammed, Alfroukh, Khadeejeh, Bairmani, Zinah Aqeel Abdulzahra, Khalid, Khalid Jehad, Abukhalaf, Salsabeel M.A., Hadhoud, Mohammed Maher, Abdrabo, Mohamed Fouad, Fathi, Mohamed, Alhouri, Hasan, Shahla, Dr Hamza, Alhadad, Qamrah, Hanan, Matly, Elapavaluru, Subbarao, Berg, Ashley, Horn, Christina, Abdelhalim, Ahmed Reda Mohamed Elsayed, Amer, Amro Essam, Elnaggar, Cinderella Omar Rageh, Hassan, Ahmed Ayman, Abdelaziz, Ali, Abdelhalim, Mohamed, Orabi, Yehia Samir Shaaban Aly, Alaraji, Zinah A., Muhaisen, Mo'nes R., Almasri, Lana, Mustafa, Dana, Hamdan, Shaher, Al-Saba'a, Yousef, Dalloul, Zaina, Alkahlout, Mohammed, Jaber, Hamza, Aldabbourosama, Osama, Abdalhadi, Alaa Abdalfattah, Hussein, Aliae AR Mohamed, Emad, Zarief Kamel, Khaled, Sarah, Mohamed, Nouralsabah, Hassanin, Ebtisam, Hamdi, Abdelhafeez, Gamal, May, Emad, Ahmed, Ragab, Abdelrahman, Azizeldin, Mohammed G, Hamza, Almthani, Omer, Alsarrah Ali Mohammed, Fadl alla, Asgad Osman Abdalla, Abdallahrs, Asia Atif Abdelrahman, Eltayeb, Aml Ahmed, Alhasan, Maali khalid mohamed abdalla, Abdelgaum, Esraa Hassan, Ahmed, Aya Mustafa, Abdulbaqi, Lamees Adil, Mohammedelhassan, Omer Abdullah, Ahmed, Musaab Mohammed Mohammed, Ali, Maha TagElser Mohammed, Mayasi, Yunis, Schroll, Stephan, Meyer, Dan, Velazco, Jorge, Ploskanych, Ludmyla, Fikes, Wanda, Bagewadi, Rohini, Dao, Marvin, White, Haley, Laviena, Alondra Berrios, Ehlers, Ashley, Shalabi-McGuire, Maysoon, Witt, Trent, Grazioli, Lorenzo, Lorini, Luca, Grandin, E. Wilson, Nunez, Jose, Reyes, Tiago, O'Briain, Diarmuid, Hunter, Stephanie, Ramanan, Mahesh, Affleck, Julia, Veerendra, Hemanth Hurkadli, Rai, Sumeet, Russell-Brown, Josie, Nourse, Mary, Joseph, Mark, Mitchell, Brook, Tenzer, Martha, Abe, Ryuzo, Cho, Hwa Jin, Jeong, In Seok, Rahman, Nadeem, Kakar, Vivek, Tamimi, Ahmed, Zabalawi, Diala, Elhennawi, Mohamed, Ghisulal, Praveen, Malik, Sadaf, Brozzi, Nicolas, Mehkri, Omar, Krishnan, Sudhir, Duggal, Abhijit, Houltham, Stuart, Graf, Jerónimo, Diaz, Roderigo, Orrego, Roderigo, Delgado, Camila, González, Joyce, Sanchez, Maria Soledad, Piagnerelli, Michael, Sarrazin, Josefa Valenzuela, Zabert, Prof. Gustavo, Espinosa, Lucio, Delgado, Paulo, Delgado, Victoria, Rincón, Diego Fernando Bautista, Yanten, Angela Maria Marulanda, Duque, Melissa Bustamante, Brodie, Daniel, Abouelmagd, Khaled, Elhazmi, Alyaa, Al-Hudaib, Abdullah, Javidfar, Jeff, Callahan, Maria, Dong, Andy, D'Orleans, Charles Crepy, Taufik, M. Azhari, Wardoyo, Elizabeth Yasmin, Gunawan, Margaretha, Trisnaningrum, Nurindah S, Irawany, Vera, Rayhan, Muhammad, Panigada, Mauro, Pesenti, Antonio, Zanella, Alberto, Grasselli, Giacomo, Colombo, Sebastiano, Martinet, Chiara, Florio, Gaetano, Antonelli, Massimo, Carelli, Simone, Grieco, Domenico L., Asaki, Motohiro, Hoshino, Kota, Salazar, Leonardo, Monsalve, Mary Alejandra Mendoza, Laffey, John, McNicholas, Bairbre, Cosgrave, David, Atif, Minha, Qutishat, Fadi, Laffey, Caoimhe, Van Der Walt, Michaeal, McCaffrey, Joseph, Bone, Allison, Trickey, Jemma, Horton, Michelle, Pearce, Stephanie, Salerno, Tania, Mohamed, Akram, Alhaddad, Salem, Bakeer, Baliad, Haitam, Shames, Shalabi, Laila, Ahmed, Mohammed Abodina, Hakeem, Yusuff, Winearls, James, Tallott, Mandy, Thomson, David, Joubert, Ivan, Arnold-Day, Christel, Piercy, Jenna, Smit, Richard van Zyl, Miller, Malcom, Seymour, Lisa, van Heyningen, Francois, Teyangesikayi, Gilbert, Fredericks, David, Hssain, Ali Ait, Aliudin, Jeffrey, Alqahtani, Al-Reem, Mohamed, Khoulod, Mohamed, Ahmed, Tan, Darwin, Villanueva, Joy, Zaqout, Ahmed, Labib, Ahmed, Kurtzman, Ethan, Ademi, Arben, Dobrita, Ana, Aoudi, Khadija El, Segura, Juliet, Giwangkancana, Gezy, Ohshimo, Shinichiro, Osatnik, Javier, Joosten, Anne, Torres, Antoni, Yang, Minlan, Motos, Ana, Luna, Carlos, Arancibia, Francisco, Williams, Virginie, Noel, Alexandre, Luque, Nestor, Fantini, Marina, García, Ruth Noemi Jorge, Alvarez, Enrique Chicote, Greti, Anna, Ceccato, Adrian, Sanchez, Angel, Vazquez, Ana Loza, Roche-Campo, Ferran, Franch-Llasat, Diego, Tuazon, Divina, Amato, Marcelo, Cassimiro, Luciana, Pola, Flavio, Ribeiro, Francis, Fonseca, Guilherme, Dalton, Heidi, Desai, Mehul, Osborn, Erik, Deeb, Hala, Arcadipane, Antonio, Martucci, Gennaro, Panarello, Giovanna, Vitiello, Stefano, Bianco, Claudia, Occhipinti, Giovanna, Rossetti, Matteo, Cuffaro, Raffaele, Siddig, Nidhal, Cho, Sung-Min, Whitman, Glenn, Sayed, Marwan El, Mokhtar, Walaa, El-Shenawy, Eslam, Shimizu, Hiroaki, Moriyama, Naoki, Kim, Jae-Burm, Kitamura, Nobuya, Gebauer, Johannes, Yokoyama, Toshiki, Al-Fares, Abdulrahman, Buabbas, Sarah, Alamad, Esam, Alawadhi, Fatma, Alawadi, Kalthoum, Khalefa, Mohamed Ahmed, Ajeel, Nourah Ahmad Abdulaziz Al, Aly, Mohammad Fathy, Al-Saleh, Abdullah, Naanouh, Abdullah, Elshourbgy, Alaa Mohammed, Gad, Mohamed Yousef, ElRazaz, Rania Mohamed, Khadadah, Ibrahim, Almumin, Ahmed Mohammed, Altarakma, Hala, Albannay, Hasan, Alsaleh, Mohammed Kh, Radwan, Mahmoud Saad Abdallah, Saadallah, Islam Ahmed, Tanaka, Hiro, Hashimoto, Satoru, Yamazaki, Masaki, Oh, Tak-Hyuck, Epler, Mark, Forney, Cathleen, Kruse, Louise, Feister, Jared, Williamson, Joelle, Grobengieser, Katherine, Gnall, Eric, Golden, Sasha, Caroline, Mara, Shapiro, Timothy, Karaj, Colleen, Thome, Lisa, Sher, Lynn, Vanderland, Mark, Welch, Mary, McDermott, Sherry, Brain, Matthew, Mineall, Sarah, Unwin, Maria, Chen, Lixian, Trezise, Tarnya, McKeon, Laurie, Kimura, Dai, Brazzi, Luca, Sales, Gabriele, Montrucchio, Giorgia, Ogston, Tawnya, Nagpal, Dave, Fischer, Karlee, Lorusso, Roberto, van Bussell, Bas, De Piero, Maria Elena, Mariani, Silvia, Rangappa, Dr Rajavardhan, Shetty, Dr Rajesh Mohan, P, Sujin Rai, Ganesan, Argin, Tharwat, Samar, Esperatti, Mariano, Fuentes, Nora Angélica, Gonzalez, Maria Eugenia, Carton, Edmund G., Sen, Ayan, Palacios, Amanda, Rainey, Deborah, Samoukoviv, Gordan, Campisi, Josie, Durham, Lucia, Neumann, Emily, Seefeldt, Cassandra, Falcucci, Octavio, Emmrich, Amanda, Guy, Jennifer, Johns, Carling, Potzner, Kelly, Zimmermann, Catherine, Espinal, Angelia, Buchtele, Nina, Schwameis, Michael, Korhnfehl, Andrea, Brock, Roman, Staudinger, Thomas, Stecher, Stephanie-Susanne, Barnikel, Michaela, Antón, Sófia, Pawlikowski, Alexandra, Zaaqoq, Akram, Galloway, Lan Anh, Merley, Caitlin, Muftah, Mohamed, Nichol, Alistair, Csete, Marc, Quesada, Luisa, Saba, Isabela, Kasugai, Daisuke, Hiraiwa, Hiroaki, Tanaka, Taku, Marwali, Eva, Purnama, Yoel, Dewayanti, Santi Rahayu, Ardiyan, Juzar, Dafsah Arifa, Siagian, Debby, Chen, Yih-Sharng, Aldhalia, Amer, Ogino, Mark, Nasa, Prashant, Matthew, Christina, Majeed, Nimisha Abdul, Hafez, Wael, Ratsep, Indrek, Post, Andra-Maris, Sillaots, Piret, Krund, Anneli, Lehiste, Merili-Helen, Lepik, Tanel, Manetta, Frank, Mihelis, Effe, Sarmiento, Iam Claire, Narasimhan, Mangala, Varrone, Michael, Komats, Mamoru, Garcia-Diaz, Julia, Harmon, Catherine, Satyapriya, S. Veena, Bhatt, Amar, Mokadam, Nahush A., Uribe, Alberto, Gonzalez, Alicia, Shi, Haixia, McKeown, Johnny, Pasek, Joshua, Fiorda, Juan, Echeverria, Marco, Moreno, Rita, Zakhary, Bishoy, Cavana, Marco, Cucino, Alberto, Foti, Giuseppe, Giani, Marco, Fumagalli, Benedetta, Chiumello, Davide, Castagna, Valentina, Dell'Amore, Andrea, Navalesi, Paolo, Shum, Hoi-Ping, Vuysteke, Alain, Usman, Asad, Acker, Andrew, Smood, Benjamin, Mergler, Blake, Sertic, Federico, Subramanian, Madhu, Sperry, Alexandra, Rizer, Nicolas, Burhan, Erlina, Rasmin, Menaldi, Akmal, Ernita, Sitompul, Faya, Lolong, Navy, Naivedh, Bhat, Erickson, Simon, Barrett, Peter, Dean, David, Daugherty, Julia, Loforte, Antonio, Khan, Irfan, Quraishi, Mohammed Abraar, DeSantis, Olivia, Nasrallah, Ahmad, So, Dominic, Kandamby, Darshana, Mandei, Jose M., Natanael, Hans, YudhaLantang, Eka, Lantang, Anastasia, Wijaya, Surya Oto, Jung, Anna, Ng, George, Ng, Wing Yiu, Ng, Pauline Yeung, Fang, Shu, Tabah, Alexis, Ratcliffe, Megan, Duroux, Maree, Alajeeli, Ahmed, Tarhabat, Ali, Adachi, Shingo, Nakao, Shota, Blanco, Pablo, Prieto, Ana, Sánchez, Jesús, Nicholson, Meghan, Butt, Warwick, Serratore, Alyssa, Delzoppo, Carmel, Janin, Pierre, Yarad, Elizabeth, Totaro, Richard, Coles, Jennifer, Pujo, Bambang, Balk, Robert, Vissing, Andy, Kapania, Esha, Hays, James, Fox, Samuel, Yantosh, Garrett, Mishin, Pavel, Adem, Safia, Yuliarto, Saptadi, Santoso, Kohar Hari, Djajalaksana, Susanthy, Fatoni, Arie Zainul, Fukuda, Masahiro, Liu, Keibun, Pelosi, Paolo, Battaglini, Denise, Robba, Chiara, Jiménez, Juan Fernando Masa, Bastos, Diego, Gaião, Sérgio, Rusmawatiningtyas, Desy, Cho, Young-Jae, Lee, Su Hwan, Kawasaki, Tatsuya, Munshi, Laveena, Sakiyalak, Pranya, Nitayavardhana, Prompak, Elagili, Mohamed Bashir, Salem, Talat Ahmed Abu, Seitz, Tamara, Arora, Rakesh, Kent, David, Marino, Daniel, Parwar, Swapnil, Cheng, Andrew, Miller, Jennene, Fujitani, Shigeki, Shimizu, Naoki, Madhok, Jai, Owyang, Clark, Buscher, Hergen, Reynolds, Claire, Abdurraouf, Abusalama, Kredan, Ali Abdulnasir, Haddud, Abdurrahman, Moharam, Saad, Maasikas, Olavi, Beljantsev, Aleksan, Mihnovits, Vladislav, Akimoto, Takako, Aizawa, Mariko, Horibe, Kanako, Onodera, Ryota, Hodgson, Carol, Burrell, Aidan, Young, Meredith, George, Timothy, Shekar, Kiran, McGuinness, Niki, Irvine, Lacey, Flynn, Brigid, Almjersah, Abdulrahman, Bakri, Ashraf, Endo, Tomoyuki, Sugiyama, Kazuhiro, Shimizu, Keiki, Fan, Eddy, Exconde, Kathleen, Ichiba, Shingo, Binnawara, Muhannud, Embarek, Hussein, Lussier, Leslie, Lotz, Gösta, Malfertheiner, Maximilian, Maier, Lars, Dreier, Esther, Kusumastuti, Neurinda Permata, McCloskey, Colin, Dabaliz, Al-Awwab, Elshazly, Tarek B, Smith, Josiah, Szuldrzynski, Konstanty S., Bielański, Piotr, Wille, Keith, Murthy, Srinivas, Parhar, Ken Kuljit S., Fiest, Kirsten M., Codan, Cassidy, Shahid, Anmol, Fayed, Mohamed, Evans, Timothy, Garcia, Rebekah, Gutierrez, Ashley, Song, Tae, Rose, Rebecca, Bennett, Suzanne, Richardson, Denise, Peek, Giles, Arora, Lovkesh, Rappapport, Kristina, Rudolph, Kristina, Sibenaller, Zita, Stout, Lori, Walter, Alicia, Herr, Daniel, Vedadi, Nazli, Bartlett, Robert, Thompson, Shaun, Hoffman, Julie, Ying, Xiaonan, Williams, Bailey, Sanchez, Emely, Akwani, Chika, Kennedy, Ryan, Elhadi, Muhammed, Griffee, Matthew, Mone, Mary, Ciullo, Anna, Kida, Yuri, Roca, Ricard Ferrer, Riera, JordI, Contreras, Sofia, Alegre, Cynthia, Kay, Christy, Fischer, Irene, Renner, Elizabeth, Taniguci, Hayato, Lee, James, Plotkin, Daniel, Citarella, Barbara Wanjiru, Merson, Laura, Hartley, Emma, Lubis, Bastian, Ikeyama, Takanari, Mortada, Alshaymaa, Alhamad, Ameen, Mechi, Ahmed, Nadar, Islam Mohsen Ali Mohamed Hassan, Alyasiri, Mohammed Saleh, Elsaid, Muhammed Zainab Alghali, Bhaskar, Balu, Jung, Jae-Seung, McGuinness, Shay, Eastwood, Glenn, Marta, Sandra Rossi, Guarracino, Fabio, Gerle, Stacy, Coxon, Emily, Claro, Bruno, Aldressi, Wafa, Eleisawy, Mahmoud, Osama, Hasnaa, Loverde, Daniel, Patil, Namrata, Parrini, Vieri, McBride, Angela, Negaard, Kathryn, Ratsch, Angela, Abdelaziz, Ahmad, Uribe, Juan David, Peris, Adriano, Sanders, Mark, Emerson, Dominic, Kamal, Muhammad, Faida, Hamza, Povoa, Pedro, Francis, Roland, Cherif, Ali, Joseph, Sunimol, Nardo, Matteo Di, Heard, Micheal, Kyle, Kimberly, Blackwell, Ray A, OUYAHIA, Amel, Biston, Patrick, Jeong, Hye Won, Smith, Reanna, Prawira, Yogi, Garcia, Arturo Huerta, Salterain, Nahikari, Meyns, Bart, Elnasser, Muhammed, Moreno, Marsha, Walia, Rajat, Mehta, Amit, Schweda, Annette, Williams, Melissa, Amkhatirah, Emad, Kim, Kyung Hoon, Assad, Alexandra, Giraldo, Estefania, Karolak, Wojtek, Balik, Martin, Pocock, Elizabeth, Gajkowski, Evan, Bedair, Mohamed, Masafumi, Kanamoto, Barrett, Nicholas, Takeyama, Yoshihiro, Park, Sunghoon, Amin, Faizan, Andriyani, Fina Meilyana, Sudakevych, Serhii, Schnur, Janos, Vera, Magdalena, Cornejo, Rodrigo, Schwarz, Patrícia, Mardini, Ana Carolina, de Paula, Thais, Neto, Ary Serpa, Villoldo, Andrea, Colafranceschi, Alexandre Siciliano, Iglesias, Alejandro Ubeda, Granjean, Juan, Melro, Lívia Maria Garcia, Romualdo, Giovana Fioravante, Gaia, Diego, Souza, Helmgton, Galas, Filomena, Mendiluce, Rafael Máñez, Sosa, Alejandra, Martinez, Ignacio, Kurosawa, Hiroshi, Almoshantaf, Mohammad Badr, Salgado, Juan, Hugi-Mayr, Beate, Charbonneau, Eric, Barzilai, Vitor Salvatore, Monteiro, Veronica, de Souza, Rodrigo Ribeiro, Harper, Michael, Suzuki, Hiroyuki, Adams, Celina, Brieva, Jorge, Khamees, Almu'atasim, Graige, Fadi, Supriatna, Moh, Nyale, George, Eltatar, Faisal Saleem, Fatani, Jihan, Baeissa, Husam, Masri, Ayman AL, Rabie, Ahmed, Hui, Mok Yee, Yamane, Masahiro, Jung, Hanna, Margaret, Ayorinde Mojisola, Nacpil, Newell, Ruck, Katja, Bakken, Rhonda, Jara, Claire, Felton, Tim, Berra, Lorenzo, Shah, Bobby, Chakraborty, Arpan, Cardona, Monika, Capatos, Gerry, Akkanti, Bindu, Orija, Abiodun, Jain, Harsh, Ito, Asami, Housni, Brahim, Low, Sennen, Iihara, Koji, Chavez, Joselito, Ramanathan, Kollengode, Zabert, Gustavo, Naidoo, Krubin, Seppelt, Ian, VanDyk, Marlice, MacDonald, Sarah, McGregor, Randy, Siebenaler, Teka, Flynn, Hannah, Lofton, Kristi, Aokage, Toshiyuki, Kvirkvelia, Bakar, Shigemitsu, Kazuaki, Moscatelli, Andrea, Fiorentino, Giuseppe, Baumgaertel, Matthias, Mba, Serge Eddy, Assy, Jana, Hutahaean, Amelya, Roush, Holly, Sichting, Kay A, Alessandri, Francesco, Burns, Debra, Alkhubouli, Taha Husayn, Salt, Gavin, Garabedian, Carl P., Millar, Jonathan, Sim, Malcolm, Mattke, Adrian, McAuley, Danny, Tadili, Jawad, Frenzel, Tim, Abuleil, Amro, Bar-Lavie, Yaron, Ortiz, Aaron Blandino, Stone, Jackie, Attokaran, Antony, Farquharson, Michael, Patel, Brij, Gunning, Derek, Baillie, Kenneth, Watson, Pia, Tamai, Kenji, Saaid, Ayoub, Anania, Pasquale, Sajinadiyasa, Gede Ketut, Kanyawati, Dyah, Salgado, Marcello, Sassine, Assad, Yudo, Bhirowo, McCaul, Scott, Lee, Bongjin, Lee, Sang Min, Afek, Arnon, Fattouh, Shimaa E, Iwashita, Yoshiaki, Fadlalmola, Hammad, Semedi, Bambang Pujo, Mansour, Noureldin Mohamed, Metiva, Jack, Van Belle, Nicole, Martin-Loeches, Ignacio, Al-Sadawi, Dr Mohammed, Kirakli, Cenk, Shimaa, Al-Touny, Ivatt, Lenny, Woon, Chia Yew, Kang, Hyun Mi, Smith, Timothy, James, Erskine, Al-Rawas, Nawar, Iwasaki, Yudai, Ashour, Hamza, King-Chung, Kenny Chan, Gudzenko, Vadim, Taccone, Fabio, Perdhana, Fajar, Lamarche, Yoan, Ribeiro, Joao Miguel, Bradic, Nikola, Van den Bossche, Klaartje, Lansink, Oude, Singh, Gurmeet, Debeuckelaere, Gerdy, Stelfox, Henry T., Yi, Cassia, Elia, Jennifer, Tribble, Thomas, Shankar, Shyam, Padmanabhan, Raj, Hallinan, Bill, Paoletti, Luca, Leyva, Yolanda, Fykuda, Tatuma, Badulak, Jenelle, Koch, Jillian, Janowaik, Lisa, Hackman, Amy, Hernandez, Deb, Osofsky, Jennifer, Donadello, Katia, Lawang, Aizah, Fine, Josh, Davidson, Benjamin, Vazquez, Andres Oswaldo Razo, Abdehaleem, Ibrahim, Kelly, Thu-Lan, Fanning, Jonathon, Premraj, Lavienraj, Porto, Diego Bastos, White, Nicole M., Bassi, Gianluigi Li, Suen, Jacky, and Fraser, John F.
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- 2024
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16. European Network for ICU-Related Respiratory Infections (ENIRRIs): a multinational, prospective, cohort study of nosocomial LRTI
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Martin-Loeches, Ignacio, Reyes, Luis Felipe, Nseir, Saad, Ranzani, Otavio, Povoa, Pedro, Diaz, Emili, and Schultz, Marcus J.
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Medical research -- Analysis -- Health aspects ,Medicine, Experimental -- Analysis -- Health aspects ,Bacterial pneumonia -- Care and treatment ,Mortality -- Analysis ,Drug resistance in microorganisms -- Care and treatment ,Value-added tax -- Analysis -- Health aspects ,Pneumonia -- Care and treatment ,Hospital patients -- Care and treatment ,Septic shock -- Care and treatment ,Acute respiratory distress syndrome -- Care and treatment ,Health care industry - Abstract
Purpose Lower respiratory tract infections (LRTI) are the most frequent infectious complication in patients admitted to the intensive care unit (ICU). We aim to report the clinical characteristics of ICU-admitted patients due to nosocomial LRTI and to describe their microbiology and clinical outcomes. Methods A prospective observational study was conducted in 13 countries over two continents from 9th May 2016 until 16th August 2019. Characteristics and outcomes of ventilator-associated pneumonia (VAP), ventilator-associated tracheobronchitis (VAT), ICU hospital-acquired pneumonia (ICU-HAP), HAP that required invasive ventilation (VHAP), and HAP in patients transferred to the ICU without invasive mechanical ventilation were collected. The clinical diagnosis and treatments were per clinical practice and not per protocol. Descriptive statistics were used to compare the study groups. Results 1060 patients with LRTI (72.5% male sex, median age 64 [50-74] years) were included in the study; 160 (15.1%) developed VAT, 556 (52.5%) VAP, 98 (9.2%) ICU-HAP, 152 (14.3%) HAP, and 94 (8.9%) VHAP. Patients with VHAP had higher serum procalcitonin (PCT) and Sequential Organ Failure Assessment (SOFA) scores. Patients with VAP or VHAP developed acute kidney injury, acute respiratory distress syndrome, multiple organ failure, or septic shock more often. One thousand eight patients had microbiological samples, and 711 (70.5%) had etiological microbiology identified. The most common microorganisms were Pseudomonas aeruginosa (18.4%) and Klebsiella spp (14.4%). In 382 patients (36%), the causative pathogen shows some antimicrobial resistance pattern. ICU, hospital and 28-day mortality were 30.8%, 37.5% and 27.5%, respectively. Patients with VHAP had the highest ICU, in-hospital and 28-day mortality rates. Conclusion VHAP patients presented the highest mortality among those admitted to the ICU. Multidrug-resistant pathogens frequently cause nosocomial LRTI in this multinational cohort study., Author(s): Ignacio Martin-Loeches [sup.1] [sup.37], Luis Felipe Reyes [sup.2] [sup.3] [sup.4], Saad Nseir [sup.5], Otavio Ranzani [sup.6], Pedro Povoa [sup.7], Emili Diaz [sup.8], Marcus J. Schultz [sup.9] [sup.10] [sup.40], Alejandro [...]
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- 2023
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17. Antibiotic allergy de-labeling in the intensive care unit: The prospective ADE-ICU study
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Alamin, Salma, Egan, Rachel, Cusack, Barbara, Sherwin, Amanda, Naylor, Emily, Carroll, Fiona, E. Ward, Marie, Kelly, Mary, Doyle, Deirdre, Martin-Loeches, Ignacio, Conlon, Niall, and Keane, Sean
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- 2025
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18. Ventilator associated tracheobronchitis and pneumonia: one infection with two faces
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Martin-Loeches, Ignacio, Povoa, Pedro, and Nseir, Saad
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Bacterial pneumonia -- Health aspects ,Bronchitis -- Health aspects ,Medical colleges -- Health aspects ,Pneumonia -- Health aspects ,Epidemiology -- Health aspects ,Health care industry - Abstract
Author(s): Ignacio Martin-Loeches [sup.1] [sup.2] [sup.8], Pedro Povoa [sup.3] [sup.4] [sup.5], Saad Nseir [sup.6] [sup.7] Author Affiliations: (1) Department of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organization (MICRO), , [...]
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- 2023
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19. Applicability of an unsupervised cluster model developed on first wave COVID-19 patients in second/third wave critically ill patients
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Rodríguez, Alejandro, Gómez, Josep, Franquet, Álvaro, Trefler, Sandra, Díaz, Emili, Sole-Violán, Jordi, Zaragoza, Rafael, Papiol, Elisabeth, Suberviola, Borja, Vallverdú, Montserrat, Jimenez-Herrera, María, Albaya-Moreno, Antonio, Canabal Berlanga, Alfonso, del Valle Ortíz, María, Carlos Ballesteros, Juan, López Amor, Lucía, Sancho Chinesta, Susana, de Alba-Aparicio, Maria, Estella, Angel, Martín-Loeches, Ignacio, and Bodi, María
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- 2024
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20. Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms
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Moharam, S.A., Abdalasalam, Sabriya, Abdalhadi, Alaa Abdalfattah, Abdalla, Naana Reyam, Abdalla, Walaa, Abdalrheem, Almthani Hamza, Abdalsalam, Ashraf, Abdeewi, Saedah, Abdelgaum, Esraa Hassan, Abdelhalim, Mohamed, Abdelkabir, Mohammed, Abdelrahman, Israa, Abdukahil, Sheryl Ann, Abdulbaqi, Lamees Adil, Abdulhamid, Salaheddin, Abdulhamid, Widyan, Abdulkadir, Nurul Najmee, Abdulwahed, Eman, Abdunabi, Rawad, Abe, Ryuzo, Abel, Laurent, Abodina, Ahmed Mohammed, Abrous, Amal, Absil, Lara, Jabal, Kamal Abu, Salah, Nashat Abu, Abusalama, Abdurraouf, Abuzaid, Tareg Abdallah, Acharya, Subhash, Acker, Andrew, Adam, Elisabeth, Adem, Safia, Ademnou, Manuella, Adewhajah, Francisca, Adrião, Diana, Afum-Adjei Awuah, Anthony, Agbogbatey, Melvin, Al Ageel, Saleh, Ahmed, Aya Mustafa, Ahmed, Musaab Mohammed, Ahmed, Shakeel, Alaraji, Zainab Ahmed, Elhefnawy Enan, Abdulrahman Ahmed, Ahmed Khalil, Reham Abdelhamid, Ahmed Mohamed Abdelaziz, Ali Mostafa, Ainscough, Kate, Airlangga, Eka, Aisa, Tharwat, Aisha, Ali, Aisha, Bugila, Hssain, Ali Ait, Tamlihat, Younes Ait, Akimoto, Takako, Akmal, Ernita, Akwani, Chika, Al Qasim, Eman, Alajeeli, Ahmed, Alali, Ahmed, Alalqam, Razi, Alameen, Aliya Mohammed, Al-Aquily, Mohammed, Alaraji, Zinah A., Albakry, Khalid, Albatni, Safa, Alberti, Angela, Aldabbourosama, Osama, Al-dabbous, Tala, Aldhalia, Amer, Aldoukali, Abdulkarim, Alegesan, Senthilkumar, Alessi, Marta, Alex, Beatrice, Alexandre, Kévin, Al-Fares, Abdulrahman, Alflite, Asil, Alfoudri, Huda, Alhadad, Qamrah, Alhaddad, Hoda Salem, Mohamed Abdalla Alhasan, Maali Khalid, Alhouri, Ahmad Nabil, Alhouri, Hasan, Ali, Adam, Ali, Imran, TagElser Mohammed Ali, Maha, Abbas, Syed Ali, Abdelghafar, Yomna Ali, Sheikh, Naseem Ali, Alidjnou, Kazali Enagnon, Aljadi, Mahmoud, Aljamal, Sarah, Alkahlout, Mohammed, Alkaseek, Akram, Alkhafajee, Qabas, Allavena, Clotilde, Allou, Nathalie, Almasri, Lana, Almjersah, Abdulrahman, Alqandouz, Raja Ahmed, Alrfaea, Walaa, Alrifaee, Moayad, Alsaadi, Rawan, Al-Saba'a, Yousef, Alshareea, Entisar, Alshenawy, Eslam, Altaf, Aneela, Alves, João Melo, Alves, João, Alves, Rita, Cabrita, Joana Alves, Amaral, Maria, Amer, Amro Essam, Amira, Nur, Adusei, Amos Amoako, Amuasi, John, Andini, Roberto, Andrejak, Claire, Angheben, Andrea, Angoulvant, François, Ankrah, Sophia, Ansart, Séverine, Anthonidass, Sivanesen, Antonelli, Massimo, Antunes de Brito, Carlos Alexandre, Apriyana, Ardiyan, Arabi, Yaseen, Aragao, Irene, Arancibia, Francisco, Araujo, Carolline, Arcadipane, Antonio, Archambault, Patrick, Arenz, Lukas, Arlet, Jean-Benoît, Arnold-Day, Christel, Arora, Lovkesh, Arora, Rakesh, Artaud-Macari, Elise, Aryal, Diptesh, Asensio, Angel, Ashley, Elizabeth A., Ashraf, Muhammad, Ashraf, Muhammad Sheharyar, Ben Ashur, Abir, Asiedu-Bekoe, Franklin, Asif, Namra, Asim, Mohammad, Assi, Grace, Assie, Jean Baptiste, Asyraf, Amirul, Atangana, Fouda, Atia, Ahmed, Atif, Minahel, Abdelrhman Abdallahrs, Asia Atif, Atique, Anika, Atlowly, Moad, Attanyake, AM Udara Lakshan, Auchabie, Johann, Aumaitre, Hugues, Auvet, Adrien, Ali Mohammed, Abdelmalek Awad, Axelsen, Eyvind W., Ayad, Ared, Hassan Helmi, Ahmed Ayman, Azemar, Laurène, Azizeldin, Mohammed, Azoulay, Cecile, Babatunde, Hakeem, Bach, Benjamin, Bachelet, Delphine, Badr, Claudine, Bævre-Jensen, Roar, Baig, Nadia, Baillie, John Kenneth, Baird, J Kevin, Bak, Erica, Bakakos, Agamemnon, Bakar, Nazreen Abu, Bakeer, Hibah Bileid, Bakri, Ashraf, Bal, Andriy, Balakrishnan, Mohanaprasanth, Bandoh, Irene, Bani-Sadr, Firouzé, Barbalho, Renata, Barbosa, Nicholas Yuri, Barclay, Wendy S., Barnett, Saef Umar, Barnikel, Michaela, Barrasa, Helena, Barrigoto, Cleide, Bartoli, Marie, Baruch, Joaquín, Basmaci, Romain, Basri, Muhammad Fadhli Hassin, Batool, AbdAlkarim, Battaglini, Denise, Bauer, Jules, Bautista Rincon, Diego Fernando, Dow, Denisse Bazan, Beane, Abigail, Bedossa, Alexandra, Bee, Ker Hong, Begum, Husna, Behilill, Sylvie, Beishuizen, Albertus, Beljantsev, Aleksandr, Bellemare, David, Beltrame, Anna, Beltrão, Beatriz Amorim, Beluze, Marine, Benech, Nicolas, Benjiman, Lionel Eric, Bennett, Suzanne, Bento, Luís, Berdal, Jan-Erik, Berdeweel, Lamis, Bergeaud, Delphine, Bergin, Hazel, Bertoli, Giulia, Bertolino, Lorenzo, Bessis, Simon, Bevilcaqua, Sybille, Bezulier, Karine, Bhatt, Amar, Bhavsar, Krishna, Bianchi, Isabella, Bianco, Claudia, Bichoka, Sandra, Bidin, Farah Nadiah, Humaid, Felwa Bin, Bin Kamarudin, Mohd Nazlin, Binnawara, Muhannud, Bisoffi, Zeno, Biston, Patrick, Bitker, Laurent, Bittaye, Mustapha, Bitton, Jonathan, Blanco-Schweizer, Pablo, Blier, Catherine, Bloos, Frank, Blot, Mathieu, Boccia, Filomena, Bodenes, Laetitia, Bogaert, Debby, Boivin, Anne-Hélène, Bolanga, Ariel, Bolaños, Isabela, Bolze, Pierre-Adrien, Bompart, François, Bonifasius, Aurelius, Bonney, Joe, Borges, Diogo, Borie, Raphaël, Bosse, Hans Martin, Botelho-Nevers, Elisabeth, Bouadma, Lila, Bouchaud, Olivier, Bouchez, Sabelline, Bouhour, Damien, Bouiller, Kévin, Bouillet, Laurence, Bouisse, Camile, Bountthasavong, Latsaniphone, Boureau, Anne-Sophie, Bourke, John, Bouscambert, Maude, Bousquet, Aurore, Boyer-Besseyre, Marielle, Boylan, Maria, Bozza, Fernando Augusto, Braconnier, Axelle, Braga, Cynthia, Brandenburger, Timo, Monteiro, Filipa Brás, Brazzi, Luca, Breen, Dorothy, Breen, Patrick, Brewster, David, Brickell, Kathy, Broadley, Tessa, Brotherton, Helen, Browne, Alex, Brozzi, Nicolas, Brunvoll, Sonja Hjellegjerde, Brusse-Keizer, Marjolein, Bryda, Petra, Buchtele, Nina, Bugaeva, Polina, Buisson, Marielle, Buonsenso, Danilo, Burhan, Erlina, Buri, Donald, Burrell, Aidan, Bustos, Ingrid G., Butnaru, Denis, Cabie, André, Cabral, Susana, Cabrita, Joana, Caceres, Eder, Cadoz, Cyril, Garcês, Rui Caetano, Calligy, Kate, Calvache, Jose Andres, Camões, João, Campana, Valentine, Campbell, Paul, Campisi, Josie, Canepa, Cecilia, Cantero, Mireia, Caoili, Janice, Caraux-Paz, Pauline, Cárcel, Sheila, Cardoso, Filipa, Cardoso, Filipe, Cardoso, Nelson, Cardoso, Sofia, Carelli, Simone, Carlier, Nicolas, Carmoi, Thierry, Carney, Gayle, Carqueja, Inês, Carret, Marie-Christine, Carrier, François Martin, Carroll, Ida, Carson, Gail, Casanova, Maire-Laure, Cascão, Mariana, Casey, Siobhan, Casimiro, José, Cassandra, Bailey, Castañeda, Silvia, Castanheira, Nidyanara, Castor-Alexandre, Guylaine, Castro, Ivo, Catarino, Ana, Catherine, François-Xavier, Cattaneo, Paolo, Cavalin, Roberta, Cavalli, Giulio Giovanni, Cavayas, Alexandros, Ceccato, Adrian, Ceesay, Masaneh, Cerkovnik, Shelby, Cervantes-Gonzalez, Minerva, Cevik, Muge, Chair, Anissa, Chakveatze, Catherine, Chan, Adrienne, Chand, Meera, Chapplain, Jean-Marc, Charpentier, Charlotte, Chas, Julie, Chaudry, Muhammad Mobin, Chávez Iñiguez, Jonathan Samuel, Chen, Anjellica, Chen, Yih-Sharng, Chenard, Léo, Cheng, Matthew Pellan, Cheret, Antoine, Chiarabini, Thibault, Chica, Julian, Chidambaram, Suresh Kumar, Tho, Leong Chin, Chirouze, Catherine, Chiumello, Davide, Cho, Sung-Min, Cholley, Bernard, Chommanam, Danoy, Chopin, Marie-Charlotte, Chow, Yock Ping, Chow, Ting Soo, Christy, Nathaniel, Chua, Hiu Jian, Chua, Jonathan, Cidade, Jose Pedro, Cisneros Herreros, José Miguel, Citarella, Barbara Wanjiru, Ciullo, Anna, Clarke, Jennifer, Claure-Del Granado, Rolando, Clohisey, Sara, Codan, Cassidy, Cody, Caitriona, Coles, Jennifer, Coles, Megan, Colin, Gwenhaël, Collins, Michael, Combs, Pamela, Connolly, Jennifer, Connor, Marie, Conrad, Anne, Conway, Elaine, Cooke, Graham S., Cordel, Hugues, Corley, Amanda, Cornelis, Sabine, Cornet, Alexander Daniel, Corpuz, Arianne Joy, Cortegiani, Andrea, Corvaisier, Grégory, Couffignal, Camille, Couffin-Cadiergues, Sandrine, Courtois, Roxane, Cousse, Stéphanie, Cowan, Juthaporn, Cregan, Rachel, Crowl, Gloria, Crump, Jonathan, Cruz, Claudina, Csete, Marc, Cullen, Ailbhe, Cummings, Matthew, Curley, Gerard, Curlier, Elodie, Curran, Colleen, Custodio, Paula, da Silva Filipe, Ana, Da Silveira, Charlene, Dabaliz, Al-Awwab, Dagens, Andrew, Dahl, John Arne, Dahly, Darren, D'Alessandro, Umberto, Daley, Peter, Dalloul, Zaina, Dalton, Heidi, Dalton, Jo, Daly, Seamus, Damas, Juliana, Dame, Joycelyn, Damien, Cammandji, Daneman, Nick, Dantas, Jorge, D'Aragon, Frédérick, de Loughry, Gillian, de Mendoza, Diego, De Montmollin, Etienne, França, Rafael Freitas de Oliveira, Isabel de Pinho Oliveira, Ana, De Rosa, Rosanna, De Rose, Cristina, de Silva, Thushan, de Vries, Peter, Deacon, Jillian, Dean, David, Debard, Alexa, DeBenedictis, Bianca, Debray, Marie-Pierre, DeCastro, Nathalie, Dechert, William, Decours, Romain, Defous, Eve, Delacroix, Isabelle, Delamou, Alexandre, Delaveuve, Eric, Delavigne, Karen, Delfos, Nathalie M., Deligiannis, Ionna, Dell'Amore, Andrea, Delmas, Christelle, Delobel, Pierre, Delsing, Corine, Demonchy, Elisa, Denis, Emmanuelle, Deplanque, Dominique, Depuydt, Pieter, Descamps, Diane, Desvallées, Mathilde, Dewayanti, Santi, Dhangar, Pathik, Diallo, Alpha, Diallo, Souleymane Taran, Diamantis, Sylvain, Dias, André, Da Silva, Fernanda Dias, Diaz, Rodrigo, Diaz, Juan Jose, Diaz, Priscila, Dibba, Bakary K., Didier, Kévin, Diehl, Jean-Luc, Dieperink, Wim, Dimet, Jérôme, Dinot, Vincent, Diop, Fara, Diouf, Alphonsine, Dishon, Yael, Djadda, Cedric, Djossou, Félix, Docherty, Annemarie B., Doherty, Helen, Dondorp, Arjen M., Donnelly, Christl A., Donohue, Yoann, Donohue, Sean, Doran, Peter, Dorival, Céline, D'Ortenzio, Eric, Doshi, Yash, Douangdala, Phouvieng, Douglas, James Joshua, Douma, Renee, Dournon, Nathalie, Downey, Joanne, Downing, Mark, Drake, Thomas, Driscoll, Aoife, Duah, Ibrahim Kwaku, Fonseca, Claudio Duarte, Dubee, Vincent, Dubos, François, Dubot-Pérès, Audrey, Ducancelle, Alexandre, Duculan, Toni, Dudman, Susanne, Duggal, Abhijit, Dunand, Paul, Dunning, Jake, Duplaix, Mathilde, Durante-Mangoni, Emanuele, Durham, Lucian, III, Dussol, Bertrand, Duthoit, Juliette, Duval, Xavier, Dyrhol-Riise, Anne Margarita, Ean, Sim Choon, Ebo, Ada, Echeverria-Villalobos, Marco, Edelstein, Michael, Egan, Siobhan, Eggesbø, Linn Margrete, Ehzaz, Khadeja, Eira, Carla, El Sanharawi, Mohammed, El Sayed, Marwan, Elabid, Mohammed, Elagili, Mohamed Bashir, Elapavaluru, Subbarao, Elbahnasawy, Mohammad, Elboshra, Sohail, Elharrar, Brigitte, Ellerbroek, Jacobien, Ellingjord-Dale, Merete, ELMagrahi, Hamida, Elmubark, Mohammad Muatasm, Elotmani, Loubna, Eloundou, Lauren, Eloy, Philippine, Elshaikhy, Basma, Elshazly, Tarek, Elsokni, Wafa, Eltayeb, Aml Ahmed, Elyazar, Iqbal, Emad, Zarief Kamel, Embarek, Hussein, Enderle, Isabelle, Endo, Tomoyuki, Eneli, Gervais, Eng, Chan Chee, Engelmann, Ilka, Enouf, Vincent, Epaulard, Olivier, Esaadi, Haneen, Esperatti, Mariano, Esperou, Hélène, Santo, Catarina Espírito, Esposito-Farese, Marina, Essaka, Rachel, Essuman, Lorinda, Estevão, João, Etienne, Manuel, Everding, Anna Greti, Evers, Mirjam, Fabre, Isabelle, Fabre, Marc, Fadera, Ismaila, Abdalla Fadlalla, Asgad Osman, Faheem, Amna, Fahy, Arabella, Fairfield, Cameron J., Fakar, Zul, Fareed, Komal, Faria, Pedro, Farooq, Ahmed, Fateena, Hanan, Fathi, Mohamed, Fatima, Salem, Fatoni, Arie Zainul, Faure, Karine, Favory, Raphaël, Fayed, Mohamed, Feely, Niamh, Fernandes, Jorge, Fernandes, Marília Andreia, Fernandes, Susana, Ferrand, François-Xavier, Devouge, Eglantine Ferrand, Ferrão, Joana, Ferraz, Mário, Ferreira, Benigno, Ferreira, Isabel, Ferreira, Bernardo, Ferreira, Sílvia, Ferriere, Nicolas, Ficko, Céline, Figueiredo-Mello, Claudia, Finlayson, William, Flament, Thomas, Fletcher, Tom, Florence, Aline-Marie, Florio, Letizia Lucia, Flynn, Brigid, Flynn, Deirdre, Foley, Jean, Fomin, Victor, Fonseca, Tatiana, Fontela, Patricia, Forrest, Karen, Forsyth, Simon, Foster, Denise, Foti, Giuseppe, Fotso, Berline, Fourn, Erwan, Fowler, Robert A., Fraher, Marianne, Franch-Llasat, Diego, Fraser, Christophe, Fraser, John F., Freire, Marcela Vieira, Ribeiro, Ana Freitas, French, Craig, Friedrich, Caren, Fritz, Ricardo, Fry, Stéphanie, Fuentes, Nora, Fukuda, Masahiro, Argin, G., Gaborieau, Valérie, Gaci, Rostane, Gagliardi, Massimo, Gagnard, Jean-Charles, Gagneux-Brunon, Amandine, Gai, Abdou, Gaião, Sérgio, Skeie, Linda Gail, Galal Mohamed Ramadan, Adham Mohamed, Gallagher, Phil, Gamble, Carrol, Gani, Yasmin, Garan, Arthur, Garcia, Rebekha, Garcia-Diaz, Julia, Garcia-Gallo, Esteban, Garimella, Navya, Garot, Denis, Garrait, Valérie, Gauli, Basanta, Gavrylov, Anatoliy, Gaymard, Alexandre, Gebauer, Johannes, Geraud, Eva, Morlaes, Louis Gerbaud, Germano, Nuno, Ghemmeid, Malak, Ghisulal, Praveen Kumar, Ghosn, Jade, Giani, Marco, Gigante, Tristan, Gilroy, Elaine, Giordano, Guillermo, Girvan, Michelle, Gissot, Valérie, Giwangkancana, Gezy, Glikman, Daniel, Glybochko, Petr, Gnall, Eric, Goco, Geraldine, Goehringer, François, Goepel, Siri, Goffard, Jean-Christophe, Goh, Jin Yi, Golács, Brigitta, Golob, Jonathan, Gomez, Kyle, Gómez-Junyent, Joan, Gominet, Marie, Gonzalez, Alicia, Gordon, Patricia, Gorenne, Isabelle, Goubert, Laure, Goujard, Cécile, Goulenok, Tiphaine, Grable, Margarite, Graf, Jeronimo, Grandin, Edward Wilson, Granier, Pascal, Grasselli, Giacomo, Grazioli, Lorenzo, Green, Christopher A., Greene, Courtney, Greenhalf, William, Greffe, Segolène, Grieco, Domenico Luca, Griffee, Matthew, Griffiths, Fiona, Grigoras, Ioana, Groenendijk, Albert, Grovogui, Fassou Mathias, Gruner, Heidi, Gu, Yusing, Guedj, Jérémie, Guego, Martin, Guerguerian, Anne-Marie, Guerreiro, Daniela, Guery, Romain, Guillaumot, Anne, Guilleminault, Laurent, Guimarães de Castro, Maisa, Guimard, Thomas, Haalboom, Marieke, Haber, Daniel, Hachemi, Ali, Haddud, Abdurrahman, Hadri, Nadir, Hafez, Wael, Haidri, Fakhir Raza, Rida Hajij, Fatima Mhd, Hakak, Sheeba, Hall, Adam, Hall, Matthew, Halpin, Sophie, Hamdan, Shaher, Hamdi, Abdelhafeez, Hameed, Jawad, Hamer, Ansley, Hamers, Raph L., Hamidfar, Rebecca, Hammarström, Bato, Hammond, Naomi, Hammond, Terese, Han, Lim Yuen, Hanan, Matly, Haniffa, Rashan, Hao, Kok Wei, Hardwick, Hayley, Harrison, Ewen M., Harrison, Janet, Ekow Harrison, Samuel Bernard, Hartman, Alan, Hasan, Sulieman, Nabil Hasan, Mohammad Ali, Hasan, Mohd Shahnaz, Hashmi, Junaid, Hashmi, Madiha, Hassan, Amoni, Hassanin, Ebtisam, Hayat, Muhammad, Hayes, Ailbhe, Hays, Leanne, Heerman, Jan, Heggelund, Lars, Helmi, Ahmed, Hendry, Ross, Hennessy, Martina, Henriquez-Trujillo, Aquiles Rodrigo, Hentzien, Maxime, Hernandez, Diana, Hershey, Andrew, Hesstvedt, Liv, Hidayah, Astarini, Higgins, Eibhlin, Higgins, Rupert, Hinton, Samuel, Hiraiwa, Hiroaki, Hirkani, Haider, Hitoto, Hikombo, Ho, Antonia, Ho, Yi Bin, Hoctin, Alexandre, Hoffmann, Isabelle, Hoh, Wei Han, Hoiting, Oscar, Holt, Rebecca, Holter, Jan Cato, Horby, Peter, Horcajada, Juan Pablo, Houas, Ikram, Houderi, Mabrouka, Hough, Catherine L., Houltham, Stuart, Ming-Yang Hsu, Jimmy, Hulot, Jean-Sébastien, Hurd, Abby, Hussain, Iqbal, Hussein, Aliae Mohamed, Hussein, Mahmood, Ibrahim, Fatima, Ibran, Bashir, Ijaz, Samreen, Ikram, M. Arfan, Illana, Carlos Cañada, Imbert, Patrick, Ansari, Muhammad Imran, Sikander, Rana Imran, Inácio, Hugo, Dominguez, Carmen Infante, Ing, Yun Sii, Ippolito, Mariachiara, Irawany, Vera, Isgett, Sarah, Isidoro, Tiago, Ismail, Nadiah, Isnard, Margaux, Istre, Mette Stausland, Itai, Junji, Ivulich, Daniel, Jaafar, Danielle, Jaafoura, Salma, Jaber, Hamza, Jabot, Julien, Jackson, Clare, Jagne, Abubacarr, Jaureguiberry, Stéphane, Jaworsky, Denise, Jego, Florence, Jelani, Anilawati Mat, Jenum, Synne, Jimbo-Sotomayor, Ruth, Joe, Ong Yiaw, Jorge García, Ruth Noemí, Jørgensen, Silje Bakken, Joseph, Cédric, Joseph, Mark, Joshi, Swosti, Jourdain, Mercé, Jouvet, Philippe, Jung, Anna, Jung, Hanna, Juzar, Dafsah, Kafif, Ouifiya, Kaguelidou, Florentia, Kaisbain, Neerusha, Kaleesvran, Thavamany, Kali, Sabina, Kalleberg, Karl Trygve, Kalomoiri, Smaragdi, Ayadi Kamaluddin, Muhammad Aisar, Kamano, Armand Saloun, Che Kamaruddin, Zul Amali, Kamarudin, Nadiah, Kamineni, Kavita, Kandamby, Darshana Hewa, Kang, Kong Yeow, Kanwal, Darakhshan, Kanyawati, Dyah, Karghul, Mohamed, Karpayah, Pratap, Karsies, Todd, Kartsonaki, Christiana, Kasugai, Daisuke, Katz, Kevin, Kay, Christy, Kayyali, Lamees, Keating, Seán, Kedia, Pulak, Kelly, Andrea, Kelly, Aoife, Kelly, Claire, Kelly, Niamh, Kelly, Sadie, Kelly, Yvelynne, Kelsey, Maeve, Kennon, Kalynn, Keomany, Sommay, Kernan, Maeve, Kerroumi, Younes, Keshav, Sharma, Khail, Shams, Khaled, Sarah, Khalid, Imrana, Khalil, Antoine, Khan, Irfan, Khan, Quratul Ain, Khanal, Sushil, Khatak, Abid, Kherajani, Krish, Kho, Michelle E., Khoo, Denisa, Khoo, Ryan, Khoo, Saye, Khoso, Muhammad Nasir, Khuwaja, Amin, Kiat, Khor How, Kida, Yuri, Kiiza, Peter, Granerud, Beathe Kiland, Kildal, Anders Benjamin, Kim, Jae Burm, Kimmoun, Antoine, Kindgen-Milles, Detlef, Kitamura, Nobuya, Kjetland Kjetland, Eyrun Floerecke, Klenerman, Paul, Klont, Rob, Bekken, Gry Kloumann, Knight, Stephen R., Kobbe, Robin, Forson, Paa Kobina, Kodippily, Chamira, Vasconcelos, Malte Kohns, Koirala, Sabin, Komatsu, Mamoru, Abebrese, Franklina Korkor, Korten, Volkan, Kouba, Stephanie, Kourouma, Mohamed Lamine, Kourouma, Karifa, Kpangon, Arsène, Krawczyk, Karolina, Kredan, Ali, Krishnan, Vinothini, Krishnan, Sudhir, Kruglova, Oksana, Krund, Anneli, Kuan, Pei Xuan, Kumar, Ashok, Kumar, Deepali, Kumar, Ganesh, Kumar, Mukesh, Kuriakose, Dinesh, Kurtzman, Ethan, Kutsogiannis, Demetrios, Kutsyna, Galyna, Bedu-Addo, Ama Kwakyewaa, Kwedi, Sylvie, Kyriakoulis, Konstantinos, Lachatre, Marie, Lacoste, Marie, Laffey, John G., Lafhej, Nadhem, Lagrange, Marie, Laine, Fabrice, Lairez, Olivier, Lakhey, Sanjay, Lambert, Marc, Lamontagne, François, Langelot-Richard, Marie, Langlois, Vincent, Lantang, Eka Yudha, Lanza, Marina, Laouénan, Cédric, Laribi, Samira, Lariviere, Delphine, Lasry, Stéphane, Lath, Sakshi, Latif, Naveed, Latifeh, Youssef, Launay, Odile, Laureillard, Didier, Lavie-Badie, Yoan, Law, Andy, Lawrence, Cassie, Lawrence, Teresa, Le, Minh, Le Bihan, Clément, Le Bris, Cyril, Le Falher, Georges, Le Fevre, Lucie, Le Hingrat, Quentin, Le Maréchal, Marion, Le Mestre, Soizic, Le Moal, Gwenaël, Le Moing, Vincent, Le Nagard, Hervé, Leal, Ema, Santos, Marta Leal, Lee, Biing Horng, Lee, Heng Gee, Lee, Su Hwan, Lee, James, Lee, Jennifer, Lee, Todd C., Lee, Yi Lin, Leeming, Gary, Lefebvre, Bénédicte, Lefebvre, Laurent, Lefèvre, Benjamin, LeGac, Sylvie, Lehiste, Merili-Helen, Lelievre, Jean-Daniel, Lellouche, François, Lemaignen, Adrien, Lemee, Véronique, Lemeur, Anthony, Lemmink, Gretchen, Lene, Ha Sha, Lennon, Jenny, León, Rafael, Leone, Marc, Lepik, Tanel, Lepiller, Quentin, Lescure, François-Xavier, Lesens, Olivier, Lesouhaitier, Mathieu, Lester-Grant, Amy, Letizia, Andrew, Letrou, Sophie, Levy, Bruno, Levy, Yves, Levy-Marchal, Claire, Lewandowska, Katarzyna, L'Her, Erwan, Bassi, Gianluigi Li, Liang, Janet, Liaquat, Ali, Liegeon, Geoffrey, Lim, Kah Chuan, Lim, Wei Shen, Lima, Chantre, Lina, Bruno, Lina, Lim, Lind, Andreas, Lingad, Maja Katherine, Lingas, Guillaume, Lion-Daolio, Sylvie, Liu, Keibun, Livrozet, Marine, Lizotte, Patricia, Loforte, Antonio, Lolong, Navy, Loon, Leong Chee, Lopes, Diogo, Lopez-Colon, Dalia, Loschner, Anthony L., Loubet, Paul, Loufti, Bouchra, Louis, Guillame, Lourenco, Silvia, Lovelace-Macon, Lara, Lee Low, Lee, Lowik, Marije, Loy, Jia Shyi, Lucet, Jean Christophe, Luna, Carlos M., Lungu, Olguta, Lunn, Miles, Luong, Liem, Luque, Nestor, Luton, Dominique, Maasikas, Olavi, Machado, Moïse, Machado, Sara, Macheda, Gabriel, Magzoub, Mustafa, Mahieu, Rafael, Mahy, Sophie, Maia, Ana Raquel, Maier, Lars S., Ascofare, Oumou Maiga, Maillet, Mylène, Maitre, Thomas, Majeed, Nimisha Abdul, Malfertheiner, Maximilian, Malik, Nadia, Mallon, Paddy, Maltez, Fernando, Malvy, Denis, Manda, Victoria, Mandelbrot, Laurent, Manetta, Frank, Mankikian, Julie, Manning, Edmund, Manuel, Aldric, Maráczi, Veronika, Sant′Ana Malaque, Ceila Maria, Marino, Flávio, Markowicz, Samuel, Marques, Ana, Marquis, Catherine, Marsh, Laura, Marsh, Brian, Marshal, Megan, Marshall, John, Martelli, Celina Turchi, Martin, Dori-Ann, Martin, Emily, Martin-Blondel, Guillaume, Martinelli, Alessandra, Martinez, F. Eduardo, Martin-Loeches, Ignacio, Martinot, Martin, Martín-Quiros, Alejandro, Martins, Ana, Martins, João, Martins, Nuno, Rego, Caroline Martins, Martucci, Gennaro, Martynenko, Olga, Marwali, Eva Miranda, Marzukie, Marsilla, Maslove, David, Mason, Sabina, Masood, Sobia, Masoud, Fatma, Massoma, Moise, Masumbe, Palmer, Mat Nor, Mohd Basri, Matan, Moshe, Fernandes, Henrique Mateus, Mathew, Meghena, Mathew, Christina, Mattei, Mathieu, Maulin, Laurence, May, Juergen, Maynar, Javier, Mayxay, Mayfong, Mazzoni, Thierry, Sweeney, Lisa Mc, McArthur, Colin, McCann, Naina, McCanny, Peter, McCarthy, Aine, McCarthy, Anne, McCloskey, Colin, McConnochie, Rachael, McDermott, Sherry, McDonald, Sarah E., McElroy, Aine, McElwee, Samuel, McEvoy, Natalie, McGeer, Allison, McLean, Kenneth A., McNally, Paul, McNicholas, Bairbre, Meaney, Edel, Mear-Passard, Cécile, Mechlin, Maggie, Medombou, Nastia, Mehkri, Omar, Mele, Ferruccio, Melo, Luis, Memon, Kashif Ali, Mendes, João João, Menkiti, Ogechukwu, Menon, Kusum, Mentré, France, Mentzer, Alexander J., Mercier, Emmanuelle, Mercier, Noémie, Merckx, Antoine, Mergeay-Fabre, Mayka, Mergler, Blake, Merson, Laura, Mesquita, António, Meta, Roberta, Metwally, Osama, Meybeck, Agnès, Meyer, Dan, Meynert, Alison M., Meysonnier, Vanina, Mezidi, Mehdi, Michelanglei, Céline, Michelet, Isabelle, Mihelis, Efstathia, Mihnovit, Vladislav, Abdullah, Duha Milad, Miller, Jennene, Miranda-Maldonado, Hugo, Misnan, Nor Arisah, Eliza Mohamed, Nik Nur, Mohamed, Nouralsabah, Mohamed, Tahira Jamal, Ads, Alaa Mohamed, Mohamed Elsayed Abdelhalim, Ahmed Reda, Mohammed, Libya, Mohammed Mostafa, Shrouk Fawze, Abdelrahman Mohammedahmed, Manahil Omer, Mohammedelhassan, Omer Abdullah, Moin, Asma, Mokhtar, Walaa, Molinos, Elena, Molloy, Brenda, Mone, Mary, Monteiro, Agostinho, Montes, Claudia, Montrucchio, Giorgia, Moore, Sarah, Moore, Shona C., Cely, Lina Morales, Morgom, Marwa, Moro, Lucia, Motherway, Catherine, Motos, Ana, Mouquet, Hugo, Perrot, Clara Mouton, Moyet, Julien, Mualla, Suleiman Haitham, Muftah, Mohamed, Mufti, Aisha Kalsoom, Muh, Ng Yong, Muhaisen, Mo'nes, Muhamad, Dzawani, Mullaert, Jimmy, Müller, Fredrik, Müller, Karl Erik, Munblit, Daniel, Ali, Syed Muneeb, Munir, Nadeem, Munshi, Laveena, Murphy, Aisling, Murray, Patrick, Murris, Marlène, Murthy, Srinivas, Musaab, Himed, Mustafa, Alamin, Mustafa, Mus'ab, Mustafa, Dana, Muvindi, Himasha, Myrodia, Dimitra Melia, Mohd-Hanafiah, Farah Nadia, Nadjm, Behzad, Nagpal, Dave, Nagrebetsky, Alex, Nagybányai-Nagy, Blanka, Boudoin, Herwin Nanda, Narasimhan, Mangala, Narayanan, Nageswaran, Nasa, Prashant, Khan, Rashid Nasim, Nasrallah, Ahmad, Nassif Metri, Adel Gerges, Nazerali-Maitland, Alasdair, Neant, Nadège, Neb, Holger, Nekliudov, Nikita, Nelder, Matthew, Nelwan, Erni, Neto, Raul, Neumann, Emily, Ng, Wing Yiu, Ng, Pauline Yeung, Nghi, Anthony, Nguyen, Duc, Choileain, Orna Ni, Leathlobhair, Niamh Ni, Niba, Nerissa, Nichol, Alistair D., Nitayavardhana, Prompak, Nonas, Stephanie, Mohd Noordin, Nurul Amani, Izzati Norharizam, Nurul Faten, North, Anita, Notari, Alessandra, Noursadeghi, Mahdad, Nowinski, Adam, Nseir, Saad, Numfor, Leonard, Nurnaningsih, Nurnaningsih, Nusantara, Dwi Utomo, Nyamankolly, Elsa, Nygaard, Anders Benteson, Brien, Fionnuala O., Callaghan, Annmarie O., O'Callaghan, Annmarie, Occhipinti, Giovanna, OConnor, Derbrenn, O'Donnell, Max, Ofori-Boadu, Lawrence, Ogston, Tawnya, Ogura, Takayuki, Oh, Tak-Hyuk, O'Halloran, Sophie, O'Hearn, Katie, Ohene, Sally-Ann, Ohshimo, Shinichiro, Oliveira, João, Oliveira, Larissa, Olliaro, Piero L., Rageh Elnaggar, Cinderella Omar, Mohammed Omer, Alsarrah Ali, Ondobo, Pierre, Ong, David S.Y., Ong, Jee Yan, Oosthuyzen, Wilna, Opavsky, Anne, Openshaw, Peter, Orakzai, Saijad, Orozco-Chamorro, Claudia Milena, Ortoleva, Jamel, Elsayed Soliman, Mohamed Osama, Osatnik, Javier, O'Shea, Linda, O'Sullivan, Miriam, Othman, Eman, Othman, Siti Zubaidah, Ouamara, Nadia, Ouissa, Rachida, Owusu, Micheal, Owusu-Asare, Ama Akyampomaa, Oziol, Eric, Pagadoy, Maïder, Pages, Justine, Palacios, Amanda, Palmarini, Massimo, Panarello, Giovanna, Panda, Prasan Kumar, Paneru, Hem, Pang, Lai Hui, Panigada, Mauro, Pansu, Nathalie, Papadopoulos, Aurélie, Parke, Rachael, Parker, Melissa, Pasquier, Jérémie, Pastene, Bruno, Patauner, Fabian, Patel, Drashti, Pathmanathan, Mohan Dass, Patrão, Luís, Patricio, Patricia, Patterson, Lisa, Pattnaik, Rajyabardhan, Paul, Christelle, Paul, Mical, Paulos, Jorge, Paxton, William A., Payen, Jean-François, Peake, Sandra L., Peariasamy, Kalaiarasu, Peek, Giles J., Peelman, Florent, Peiffer-Smadja, Nathan, Peigne, Vincent, Pejkovska, Mare, Pelosi, Paolo, Peltan, Ithan D., Pereira, Rui, Perez, Daniel, Perpoint, Thomas, Pesenti, Antonio, Pestre, Vincent, Petrou, Lenka, Petrovic, Michele, Petrov-Sanchez, Ventzislava, Pettersen, Frank Olav, Peytavin, Gilles, Philips, Richard Odame, Phonemixay, Ooyanong, Phoutthavong, Soulichanya, Piagnerelli, Michael, Picard, Walter, Picone, Olivier, de Piero, Maria, Piersma, Djura, Pimentel, Carlos, Pinto, Raquel, Pires, Catarina, Piroth, Lionel, Pitaloka, Ayodhia, Piubelli, Chiara, Pius, Riinu, Piva, Simone, Plantier, Laurent, Png, Hon Shen, Poissy, Julien, Pokeerbux, Ryadh, Poli, Sergio, Pollakis, Georgios, Ponscarme, Diane, Porto, Diego Bastos, Post, Andra-Maris, Postma, Douwe F., Povoa, Pedro, Póvoas, Diana, Powis, Jeff, Prapa, Sofia, Praphasiri, Viladeth, Preau, Sébastien, Prebensen, Christian, Preiser, Jean-Charles, Prinssen, Anton, Pritchard, Mark G., Dilanthi Priyadarshani, Gamage Dona, Proença, Lucia, Pudota, Sravya, Semedi, Bambang Pujo, Pulicken, Mathew, Puplampu, Peter, Purcell, Gregory, Quesada, Luisa, Quinones-Cardona, Vilmaris, Quist-Paulsen, Else, Quraishi, Mohammed, Qutishat, Fadi, Rabaa, Maia, Rabaud, Christian, Rabindrarajan, Ebenezer, Rafael, Aldo, Rafiq, Marie, Ragab, Abdelrahman, Rahardjani, Mutia, Ullah, Arslan Rahat, Haji Ab Rahman, Ahmad Kashfi, Rahman, Rozanah Abd, Rainieri, Fernando, Rajahram, Giri Shan, Ramachandran, Pratheema, Ramakrishnan, Nagarajan, Ramalho, José, Ramli, Ahmad Afiq, Rammaert, Blandine, Ramos, Grazielle Viana, Rana, Asim, Rangappa, Rajavardhan, Ranjan, Ritika, Rapp, Christophe, Rashan, Aasiyah, Rashan, Thalha, Rasheed, Ghulam, Rasmin, Menaldi, Rätsep, Indrek, Rau, Cornelius, Ravi, Tharmini, Raza, Ali, Real, Andre, Rebaudet, Stanislas, Redl, Sarah, Reeve, Brenda, Rehman, Attaur, Rehman Khalid, Muhammad Osama, Reikvam, Dag Henrik, Reis, Renato, Rello, Jordi, Remppis, Jonathan, Remy, Martine, Ren, Hongru, Renk, Hanna, Resseguier, Anne-Sophie, Revest, Matthieu, Rewa, Oleksa, Reyes, Luis Felipe, Ribeiro, Maria Ines, Ricchiuto, Antonia, Richardson, David, Richardson, Denise, Richier, Laurent, Atikah Ahmad Ridzuan, Siti Nurul, Rios, Ana L., Rishu, Asgar, Rispal, Patrick, Risso, Karine, Rivera Nuñez, Maria Angelica, Robba, Chiara, Roberto, André, Roberts, Stephanie, Roberts, Charles, Robertson, David L., Robineau, Olivier, Roca, Anna, Roche-Campo, Ferran, Rodari, Paola, Rodeia, Simão, Roessler, Bernhard, Roger, Claire, Roger, Pierre-Marie, Rojek, Amanda, Roncon-Albuquerque, Roberto, Jr., Roriz, Mélanie, Rosa-Calatrava, Manuel, Rose, Michael, Rosenberger, Dorothea, Rossanese, Andrea, Rossetti, Matteo, Rossignol, Patrick, Roy, Carine, Roze, Benoît, Rusmawatiningtyas, Desy, Russell, Clark D., Ryan, Maeve, Ryckaert, Steffi, Holten, Aleksander Rygh, Saba, Isabela, Sadaf, Sairah, Sadat, Musharaf, Sahraei, Valla, Said, Abdurraouf, Saidani, Nadia, Sakiyalak, Pranya, Sako, Fodé Bangaly, Salah, Moamen, Salah Eldin Mohamed Abbas, Ali Alaa, Salahuddin, Nawal, Salazar, Leonardo, Saleem, Jodat, Alyasiri, Mohammed Saleh, Abu Salem, Talat Ahmed, Sales, Gabriele, Gandonniere, Charlotte Salmon, Salvator, Hélène, Samardali, Dana, Samardali, Shaden, Shaaban Aly Orabi, Yehia Samir, Sanchez, Emely, Sanchez, Olivier, Sanchez de Oliveira, Kizy, Sanchez-Miralles, Angel, Sancho-Shimizu, Vanessa, Sandhu, Gyan, Sandhu, Zulfiqar, Sandrine, Pierre-François, Săndulescu, Oana, Santos, Marlene, 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Siaw-Frimpong, Moses, Sibiude, Jeanne, Sibounheuang, Bountoy, Siddig, Nidhal, Siddiqui, Atif, Siddiqui, Maqsood Ahmed, Sigfrid, Louise, Sillah, Fatoumata, Sillaots, Piret, Silva, Catarina, Silva, Maria Joao, Silva, Rogério, Lim Heng, Benedict Sim, Sin, Wai Ching, Sinatti, Dario, Singh, Mahendra, Singh, Punam, Sitompul, Pompini Agustina, Sivam, Karisha, Skogen, Vegard, Smith, Sue, Smood, Benjamin, Smyth, Coilin, Snacken, Morgane, So, Dominic, Soh, Tze Vee, Solberg, Lene Bergendal, Solomon, Joshua, Solomon, Tom, Somers, Emily, Sommet, Agnès, Song, Myung Jin, Song, Rima, Song, Tae, Chia, Jack Song, Søraas, Arne, Sotto, Albert, Soum, Edouard, Sousa, Ana Chora, Sousa, Marta, Uva, Maria Sousa, Souza-Dantas, Vicente, Sow, Mamadou Saliou, Sperry, Alexandra, Spinuzza, Elisabetta, Ruwan Sri Darshana, B. P. Sanka, Sriskandan, Shiranee, Stabler, Sarah, Staudinger, Thomas, Stecher, Stephanie-Susanne, Steinsvik, Trude, Stienstra, Ymkje, Stiksrud, Birgitte, Stolz, Eva, Stone, Amy, Streinu-Cercel, Anca, Streinu-Cercel, Adrian, Strong, Geoff, Stuart, Ami, Stuart, David, Su, Richa, Subekti, Decy, Suen, Gabriel, Suen, Jacky Y., Sukumar, Prasanth, Sultana, Asfia, Summers, Charlotte, Supic, Dubravka, Suppiah, Deepashankari, Surovcová, Magdalena, Suwarti, Atie, Svistunov, Andrey, Syahrin, Sarah, Sylverken, Augustina, Syrigos, Konstantinos, Sztajnbok, Jaques, Szuldrzynski, Konstanty, Tabrizi, Shirin, Taccone, Fabio S., Tagherset, Lysa, Taib, Shahdattul Mawarni, Taleb, Sara, Talla, Cheikh, Talsma, Jelmer, Tamisier, Renaud, Tampubolon, Maria Lawrensia, Tan, Kim Keat, Tan, Yan Chyi, Tanaka, Hiroyuki, Tanaka, Taku, Taniguchi, Hayato, Taqdees, Huda, Taqi, Arshad, Tardivon, Coralie, Kamal Mostafa, Yousef Tarek, Tarhabat, Ali, Tattevin, Pierre, Taufik, M Azhari, Tawfik, Hassan, Tee, Tze Yuan, Teixeira, João, Tejada, Sofia, Tellier, Marie-Capucine, Teoh, Sze Kye, Teotonio, Vanessa, Téoulé, François, Terrier, Olivier, Terzi, Nicolas, Tessier-Grenier, Hubert, Tey, Adrian, Mohd Thabit, Alif Adlan, Thakur, Anand, Tham, Zhang Duan, Thangavelu, Suvintheran, Theron, Elmi, Thibault, Vincent, Thiberville, Simon-Djamel, Thill, Benoît, Thirumanickam, Jananee, Thompson, Niamh, Thompson, Shaun, Thomson, Emma C., Thomson, David, Thorpe, Mathew, Thurai, Surain Raaj Thanga, Thwaites, Ryan S., Tierney, Paul, Tieroshyn, Vadim, Timashev, Peter S., Timsit, Jean-François, Tirupakuzhi Vijayaraghavan, Bharath Kumar, Tissot, Noémie, Toal, Fiona, Yang Toh, Jordan Zhien, Toki, Maria, Tonby, Kristian, Tonnii, Sia Loong, Torre, Marta, Torres, Antoni, Torres, Margarida, Santos-Olmo, Rosario Maria Torres, Torres-Zevallos, Hernando, Tounkara, Aboubacar, Towers, Michael, Traoré, Fodé Amara, Trapani, Tony, Tromeur, Cécile, Trontzas, Ioannis, Trouillon, Tiffany, Truong, Jeanne, Tual, Christelle, Tubiana, Sarah, Tuite, Helen, Turgeon, Alexis F., Turmel, Jean-Marie, Turtle, Lance C.W., Tveita, Anders, Twardowski, Pawel, Uchiyama, Makoto, Udayanga, PG Ishara, Udy, Andrew, Ullrich, Roman, Uribe, Alberto, Usman, Asad, Usuf, Effua, Uyeki, Timothy M., Vajdovics, Cristinava, Valentini, Piero, Val-Flores, Luís, Van de Velde, Stijn, van den Berge, Marcel, van der Feltz, Machteld, van der Palen, Job, van der Valk, Paul, Van Der Vekens, Nicky, Van der Voort, Peter, Van Der Werf, Sylvie, van Gulik, Laura, Van Hattem, Jarne, van Netten, Carolien, van Veen, Ilonka, Vanel, Noémie, Vanoverschelde, Henk, Varrone, Michael, Vasudayan, Shoban Raj, Vauchy, Charline, Vecham, Pavan Kumar, Veeran, Shaminee, Veislinger, Aurélie, Vencken, Sebastian, Ventura, Sara, Verbon, Annelies, Vidal, José Ernesto, Vieira, César, Vijayan, Deepak, Villar, Judit, Villeneuve, Pierre-Marc, Villoldo, Andrea, Vishwanathan, Gayatri, Visseaux, Benoit, Visser, Hannah, Vitiello, Chiara, Vongsouvath, Manivanh, Vonkeman, Harald, Vuotto, Fanny, Wahab, Suhaila Abdul, Wahab, Noor Hidayu, Wahid, Nadirah Abdul, Wainstein, Marina, Walsh, Laura, Shukeri, Wan Fadzlina Wan Muhd, Wang, Chih-Hsien, Webb, Steve, Wei, Jia, Weil, Katharina, Wen, Tan Pei, Wesam, Hassi, Wesselius, Sanne, West, T. Eoin, Wham, Murray, Whelan, Bryan, White, Nicole, Wicky, Paul Henri, Wiedemann, Aurélie, Wijaya, Surya Otto, Wille, Keith, Willems, Sue, Williams, Bailey, Williams, Patricia J., Williams, Virginie, Wils, Evert-Jan, Wittman, Jessica, Wong, Calvin, Wong, Xin Ci, Wong, Yew Sing, Wong, Teck Fung, Wright, Natalie, Xian, Lim Saio, Xynogalas, Ioannis, Binti Mohd Yakop, Siti Rohani, Yamazaki, Masaki, Yarad, Elizabeth, Yazdanpanah, Yazdan, Hing, Nicholas Yee Liang, Mahmoud Abdelaal, Abdelrahman Yehia, Yelnik, Cécile, Yeoh, Chian Hui, Yerkovich, Stephanie, Yiaye, Touxiong, Yokoyama, Toshiki, Yonis, Hodane, Yousif, Obada, Yuliarto, Saptadi, Zaaqoq, Akram, Zabbe, Marion, Zabert, Gustavo E., Zacharowski, Kai, Zahid, Masliza, Zahran, Maram, Binti Zaidan, Nor Zaila, Zambon, Maria, Zambrano, Miguel, Zanella, Alberto, Zaynah, Nurul, Zayyad, Hiba, Zoufaly, Alexander, Zucman, David, Ibáñez-Prada, Elsa D., Gonçalves, Bronner P., Baruch, Joaquin, Escher, Martina, Philippy, Fred, Kutsogiannis, Demetrios James, Vaillant, Michel, and Olliaro, Piero
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- 2024
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21. Profiling the dysregulated immune response in sepsis: overcoming challenges to achieve the goal of precision medicine
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Cajander, Sara, Kox, Matthijs, Scicluna, Brendon P, Weigand, Markus A, Mora, Raquel Almansa, Flohé, Stefanie B, Martin-Loeches, Ignacio, Lachmann, Gunnar, Girardis, Massimo, Garcia-Salido, Alberto, Brunkhorst, Frank M, Bauer, Michael, Torres, Antoni, Cossarizza, Andrea, Monneret, Guillaume, Cavaillon, Jean-Marc, Shankar-Hari, Manu, Giamarellos-Bourboulis, Evangelos J, Winkler, Martin Sebastian, Skirecki, Tomasz, Osuchowski, Marcin, Rubio, Ignacio, Bermejo-Martin, Jesus F, Schefold, Joerg C, and Venet, Fabienne
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- 2024
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22. Author Correction: Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment
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Greene, Chris, Connolly, Ruairi, Brennan, Declan, Laffan, Aoife, O’Keeffe, Eoin, Zaporojan, Lilia, O’Callaghan, Jeffrey, Thomson, Bennett, Connolly, Emma, Argue, Ruth, Meaney, James F. M., Martin-Loeches, Ignacio, Long, Aideen, Cheallaigh, Cliona Ni, Conlon, Niall, Doherty, Colin P., and Campbell, Matthew
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- 2024
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23. Comprehensive study of mechanical power in controlled mechanical ventilation: Prevalence of elevated mechanical power and component analysis
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González-Castro, Alejandro, Medina Villanueva, Alberto, Escudero-Acha, Patricia, Fajardo Campoverdi, Aurio, Gordo Vidal, Federico, Martin-Loeches, Ignacio, Rocha, Angelo Roncalli, Romero, Marta Costa, Hernández López, Marianela, Ferrando, Carlos, Protti, Alessandro, and Modesto i Alapont, Vicent
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- 2024
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24. Association of obesity on the outcome of critically ill patients affected by COVID-19
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Rodríguez, Alejandro, Martín-Loeches, Ignacio, Moreno, Gerard, Díaz, Emili, Ferré, Cristina, Salgado, Melina, Marín-Corral, Judith, Estella, Angel, Solé-Violán, Jordi, Trefler, Sandra, Zaragoza, Rafael, Socias, Lorenzo, Borges-Sa, Marcio, Restrepo, Marcos I, Guardiola, Juan J, Reyes, Luis F, Albaya-Moreno, Antonio, Berlanga, Alfonso Canabal, Ortiz, María del Valle, Ballesteros, Juan Carlos, Chinesta, Susana Sancho, Laderas, Juan Carlos Pozo, Gómez, Josep, and Bodí, María
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- 2024
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25. Optimizing artificial intelligence in sepsis management: Opportunities in the present and looking closely to the future
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O'Reilly, Darragh, McGrath, Jennifer, and Martin-Loeches, Ignacio
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- 2024
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26. Impact of Empirical Treatment Recommendations From 2017 European Guidelines for Nosocomial Pneumonia
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Calabretta, Davide, Cilloniz, Catia, Gabarrus, Albert, Motos, Ana, Galli, Flavia, Ferrer, Miquel, Fernandez-Barat, Laia, Palomeque, Andrea, Mistraletti, Giovanni, Panigada, Mauro, Pitart, Cristina, Espasa, Mateu, Martin-Loeches, Ignacio, and Torres, Antoni
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- 2024
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27. ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia
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Martin-Loeches, Ignacio, Torres, Antoni, Nagavci, Blin, Aliberti, Stefano, Antonelli, Massimo, Bassetti, Matteo, and Bos, Lieuwe D.
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Gilead Sciences Inc. ,Pfizer Inc. ,Insmed Inc. ,Task forces -- Health aspects ,Medical colleges -- Health aspects ,Health care industry - Abstract
Purpose Severe community-acquired pneumonia (sCAP) is associated with high morbidity and mortality, and whilst European and non-European guidelines are available for community-acquired pneumonia, there are no specific guidelines for sCAP. Methods The European Respiratory Society (ERS), European Society of Intensive Care Medicine (ESICM), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), and Latin American Thoracic Association (ALAT) launched a task force to develop the first international guidelines for sCAP. The panel comprised a total of 18 European and four non-European experts, as well as two methodologists. Eight clinical questions for sCAP diagnosis and treatment were chosen to be addressed. Systematic literature searches were performed in several databases. Meta-analyses were performed for evidence synthesis, whenever possible. The quality of evidence was assessed with GRADE (Grading of Recommendations, Assessment, Development and Evaluation). Evidence to Decision frameworks were used to decide on the direction and strength of recommendations. Results Recommendations issued were related to diagnosis, antibiotics, organ support, biomarkers and co-adjuvant therapy. After considering the confidence in effect estimates, the importance of outcomes studied, desirable and undesirable consequences of treatment, cost, feasibility, acceptability of the intervention and implications to health equity, recommendations were made for or against specific treatment interventions. Conclusions In these international guidelines, ERS, ESICM, ESCMID, and ALAT provide evidence-based clinical practice recommendations for diagnosis, empirical treatment, and antibiotic therapy for sCAP, following the GRADE approach. Furthermore, current knowledge gaps have been highlighted and recommendations for future research have been made., Author(s): Ignacio Martin-Loeches [sup.1] [sup.2] [sup.3] [sup.4], Antoni Torres [sup.3] [sup.4], Blin Nagavci [sup.5], Stefano Aliberti [sup.6] [sup.7], Massimo Antonelli [sup.8], Matteo Bassetti [sup.9], Lieuwe D. Bos [sup.10], James D. [...]
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- 2023
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28. Antifungal stewardship in critically ill patients
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De Pascale, Gennaro, Martin-Loeches, Ignacio, and Nseir, Saad
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Hospital patients ,Health care industry - Abstract
Author(s): Gennaro De Pascale [sup.1] [sup.2], Ignacio Martin-Loeches [sup.3] [sup.4], Saad Nseir [sup.5] [sup.6] Author Affiliations: (1) grid.8142.f, 0000 0001 0941 3192, Dipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche [...]
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- 2023
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29. Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA): an international prospective multicenter cohort study
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Sonneville, Romain, de Montmollin, Etienne, Contou, Damien, Ferrer, Ricard, Gurjar, Mohan, Klouche, Kada, Sarton, Benjamine, Demeret, Sophie, Bailly, Pierre, da Silva, Daniel, Escudier, Etienne, Le Guennec, Loic, Chabanne, Russel, Argaud, Laurent, Ben Hadj Salem, Omar, Thyrault, Martial, Frerou, Aurélien, Louis, Guillaume, De Pascale, Gennaro, Horn, Janneke, Helbok, Raimund, Geri, Guillaume, Bruneel, Fabrice, Martin-Loeches, Ignacio, Taccone, Fabio Silvio, De Waele, Jan J., Ruckly, Stéphane, Staiquly, Quentin, Citerio, Giuseppe, and Timsit, Jean-François
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- 2023
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30. Final approval for corticosteroids in severe CAP? For sure, in septic shock
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Martin-Loeches, Ignacio, Nagavci, Blin, and Torres, Antoni
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- 2023
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31. Characteristics and outcomes of patients with acute myeloid leukemia admitted to intensive care unit with acute respiratory failure: a post-hoc analysis of a prospective multicenter study
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Secreto, Carolina, Chean, Dara, van de Louw, Andry, Kouatchet, Achille, Bauer, Philippe, Cerrano, Marco, Lengliné, Etienne, Saillard, Colombe, Chow-Chine, Laurent, Perner, Anders, Pickkers, Peter, Soares, Marcio, Rello, Jordi, Pène, Frédéric, Lemiale, Virginie, Darmon, Michael, Fodil, Sofiane, Martin-Loeches, Ignacio, Mehta, Sangeeta, Schellongowski, Peter, Azoulay, Elie, and Mokart, Djamel
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- 2023
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32. Pneumocystis jirovecii pneumonia in intensive care units: a multicenter study by ESGCIP and EFISG
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Giacobbe, Daniele Roberto, Dettori, Silvia, Di Pilato, Vincenzo, Asperges, Erika, Ball, Lorenzo, Berti, Enora, Blennow, Ola, Bruzzone, Bianca, Calvet, Laure, Capra Marzani, Federico, Casabella, Antonio, Choudaly, Sofia, Dartevel, Anais, De Pascale, Gennaro, Di Meco, Gabriele, Fallon, Melissa, Galerneau, Louis-Marie, Gallego, Miguel, Giacomini, Mauro, González Sáez, Adolfo, Hänsel, Luise, Icardi, Giancarlo, Koehler, Philipp, Lagrou, Katrien, Lahmer, Tobias, Lewis White, P., Magnasco, Laura, Marchese, Anna, Marelli, Cristina, Marín-Arriaza, Mercedes, Martin-Loeches, Ignacio, Mekontso-Dessap, Armand, Mikulska, Malgorzata, Mularoni, Alessandra, Nordlander, Anna, Poissy, Julien, Russelli, Giovanna, Signori, Alessio, Tascini, Carlo, Vaconsin, Louis-Maxime, Vargas, Joel, Vena, Antonio, Wauters, Joost, Pelosi, Paolo, Timsit, Jean-Francois, and Bassetti, Matteo
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- 2023
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33. Impact of macrolide treatment on long-term mortality in patients admitted to the ICU due to CAP: a targeted maximum likelihood estimation and survival analysis
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Reyes, Luis Felipe, Garcia, Esteban, Ibáñez-Prada, Elsa D., Serrano-Mayorga, Cristian C., Fuentes, Yuli V., Rodríguez, Alejandro, Moreno, Gerard, Bastidas, Alirio, Gómez, Josep, Gonzalez, Angélica, Frei, Christopher R., Celi, Leo Anthony, Martin-Loeches, Ignacio, and Waterer, Grant
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- 2023
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34. Timing of intubation and ICU mortality in COVID-19 patients: a retrospective analysis of 4198 critically ill patients during the first and second waves
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Manrique, Sara, Claverias, Laura, Magret, Mónica, Masclans, Joan Ramón, Bodi, María, Trefler, Sandra, Canadell, Laura, Díaz, Emili, Sole-Violan, Jordi, Bisbal-Andrés, Elena, Natera, Ruth González, Moreno, Antonio Albaya, Vallverdu, Montserrat, Ballesteros, Juan Carlos, Socias, Lorenzo, Vidal, Federico Gordo, Sancho, Susana, Martin-Loeches, Ignacio, and Rodriguez, Alejandro
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- 2023
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35. Research priorities for therapeutic plasma exchange in critically ill patients
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David, Sascha, Russell, Lene, Castro, Pedro, van de Louw, Andry, Zafrani, Lara, Pirani, Tasneem, Nielsen, Nathan D., Mariotte, Eric, Ferreyro, Bruno L., Kielstein, Jan T., Montini, Luca, Brignier, Anne C., Kochanek, Matthias, Cid, Joan, Robba, Chiara, Martin-Loeches, Ignacio, Ostermann, Marlies, and Juffermans, Nicole P.
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- 2023
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36. Outcomes in participants with ventilated nosocomial pneumonia and organ failure treated with ceftolozane/tazobactam versus meropenem: a subset analysis of the phase 3, randomized, controlled ASPECT-NP trial
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Martin-Loeches, Ignacio, Shorr, Andrew F., Wunderink, Richard G., Kollef, Marin H., Timsit, Jean-François, Yu, Brian, Huntington, Jennifer A., Jensen, Erin, and Bruno, Christopher J.
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- 2023
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37. Risk factors for developing ventilator-associated lower respiratory tract infection in patients with severe COVID-19: a multinational, multicentre study, prospective, observational study
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Reyes, Luis Felipe, Rodriguez, Alejandro, Fuentes, Yuli V., Duque, Sara, García-Gallo, Esteban, Bastidas, Alirio, Serrano-Mayorga, Cristian C., Ibáñez-Prada, Elsa D., Moreno, Gerard, Ramirez-Valbuena, Paula C., Ospina-Tascon, Gustavo, Hernandez, Glenn, Silva, Edwin, Díaz, Ana Maria, Jibaja, Manuel, Vera-Alarcon, Magdalena, Díaz, Emili, Bodí, María, Solé-Violán, Jordi, Ferrer, Ricard, Albaya-Moreno, Antonio, Socias, Lorenzo, Figueroa, William, Lozano-Villanueva, Jose L., Varón-Vega, Fabio, Estella, Ángel, Loza-Vazquez, Ana, Jorge-García, Ruth, Sancho, Isabel, Shankar-Hari, Manu, and Martin-Loeches, Ignacio
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- 2023
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38. Essential Emergency and Critical Care: a consensus among global clinical experts
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Schell, Carl Otto, Khalid, Karima, Wharton-Smith, Alexandra, Oliwa, Jacquie, Sawe, Hendry R, Roy, Nobhojit, Sanga, Alex, Marshall, John C, Rylance, Jamie, Hanson, Claudia, Kayambankadzanja, Raphael K, Wallis, Lee A, Jirwe, Maria, Baker, Tim, Asghar, Adam, Laytin, Adam D, Holloway, Adrian J, Adib, Ahmed Rhassane El, Michaelides, Alexia, Munoz, Alvaro Coronado, Muzuka, Amos, Fernández, Analía, Pembe, Andrea B, Wellhagen, Andreas, Smith, Andrew G, Gadgil, Anita, Hvarfner, Anna, Abayadeera, Anuja, Agulnik, Asya, Godard, Aurélie, Venkatesh, Balasubramanian, Yousif, Bargo Mahamat, Morton, Bhakti Sarang Ben, Kumar, Bharath, Vijayaraghavan, Tirupakuzhi, King, Bobby, Rice, Brian, Thwaites, C Louise, Tai, Chian Wern, Owoo, Christian, Sendagire, Cornelius, Petersen, Dan Brun, Tatay, Daniel, Skinner, David Lee, Kinyua, Denis, Ghosh, Dhruva, Aryal, Diptesh, Mlombwa, Donald, Thi, Duyen, Bui, Hanh, Lugazia, Edwin R, Riviello, Elisabeth, Molyneux, Elizabeth M, Heyns, Ellena, Nsutebu, Emmanuel Fru, Montalvo, Erika, Moreno, Ernesto Gerardo, Kanyangira, Esther Banda, Muttalib, Fiona, Mupeta, Francis, Diaz, Franco, Bulamba, Fred, Nzanzu, Furaha, Pascal, Blaise, Wooldridge, Gavin, Mwakisambwe, Gibonce, Richards, Guy A, Ammar, Hala, Mangat, Halinder S, Ghali, Hasanein H, Shah, Hiral A, Shum, Hoi Ping, Abdullahi, Ibrahim Salim, Martin-Loeches, Ignacio, von der Osten, Ingrid T, Mcknight, Jacob, Lee, James S, Namagga, Jane Kasozi, Eriksen, Jaran, Armour-Marshall, Jasmine, Kellett, John, Metcalfe, John Z, Moore, Jolene, Blixt, Jonas, Langton, Josephine, Mejia, Juan Gutierrez, Silesky-Jiménez, Juan Ignacio, Soni, Kapil Dev, Kohne, Karl Martin, Rowan, Kathryn, Yokobatake, Kazuhiro, Doi, Kent, Rudd, Kristina E, Akuamoah-Boateng, Kwame Asante, Irestedt, Lars, Losonczy, Lia I, Zhang, Lina, Kurland, Lisa, Guinness, Lorna, and Bains, Lovenish
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Health Services and Systems ,Health Sciences ,Health Services ,Clinical Research ,Emergency Care ,Generic health relevance ,Good Health and Well Being ,COVID-19 ,Consensus ,Critical Care ,Emergency Medical Services ,Humans ,SARS-CoV-2 ,EECC Collaborators ,EECC Collaborators* ,health policy ,health services research ,health systems ,surgery ,Health services and systems ,Public health - Abstract
BackgroundGlobally, critical illness results in millions of deaths every year. Although many of these deaths are potentially preventable, the basic, life-saving care of critically ill patients are often overlooked in health systems. Essential Emergency and Critical Care (EECC) has been devised as the care that should be provided to all critically ill patients in all hospitals in the world. EECC includes the effective care of low cost and low complexity for the identification and treatment of critically ill patients across all medical specialties. This study aimed to specify the content of EECC and additionally, given the surge of critical illness in the ongoing pandemic, the essential diagnosis-specific care for critically ill patients with COVID-19.MethodsIn a Delphi process, consensus (>90% agreement) was sought from a diverse panel of global clinical experts. The panel iteratively rated proposed treatments and actions based on previous guidelines and the WHO/ICRC's Basic Emergency Care. The output from the Delphi was adapted iteratively with specialist reviewers into a coherent and feasible package of clinical processes plus a list of hospital readiness requirements.ResultsThe 269 experts in the Delphi panel had clinical experience in different acute medical specialties from 59 countries and from all resource settings. The agreed EECC package contains 40 clinical processes and 67 requirements, plus additions specific for COVID-19.ConclusionThe study has specified the content of care that should be provided to all critically ill patients. Implementing EECC could be an effective strategy for policy makers to reduce preventable deaths worldwide.
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- 2021
39. Direct association between pharyngeal viral secretion and host cytokine response in severe pandemic influenza
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Castro Carmen, Eiros Jose Mª, Resino Salvador, Bobillo Felipe, Gandía Francisco, Marcos Maria, Merino Pedro, León Cristobal, Fernandez Victoria, Gallegos Maria C, Maravi Enrique, Gordón Mónica, Andaluz David, Loza Ana, Socias Lorenzo, Martin-Sanchez Fernando, Lopez-Campos Guillermo, Ran Longsi, Blanco Jesús, Xu Luoling, Pumarola Tomás, Banner David, Martin-Loeches Ignacio, Ramirez Paula, Anton Andres, Almansa Raquel, Mateo Paula, Gonzalez-Rivera Milagros, Rello Jordi, de Lejarazu Raul, Kelvin David J, and Bermejo-Martin Jesus F
- Subjects
cytokines ,critical ,influenza ,patients ,virus ,Infectious and parasitic diseases ,RC109-216 - Abstract
Abstract Background Severe disease caused by 2009 pandemic influenza A/H1N1virus is characterized by the presence of hypercytokinemia. The origin of the exacerbated cytokine response is unclear. As observed previously, uncontrolled influenza virus replication could strongly influence cytokine production. The objective of the present study was to evaluate the relationship between host cytokine responses and viral levels in pandemic influenza critically ill patients. Methods Twenty three patients admitted to the ICU with primary viral pneumonia were included in this study. A quantitative PCR based method targeting the M1 influenza gene was developed to quantify pharyngeal viral load. In addition, by using a multiplex based assay, we systematically evaluated host cytokine responses to the viral infection at admission to the ICU. Correlation studies between cytokine levels and viral load were done by calculating the Spearman correlation coefficient. Results Fifteen patients needed of intubation and ventilation, while eight did not need of mechanical ventilation during ICU hospitalization. Viral load in pharyngeal swabs was 300 fold higher in the group of patients with the worst respiratory condition at admission to the ICU. Pharyngeal viral load directly correlated with plasma levels of the pro-inflammatory cytokines IL-6, IL-12p70, IFN-γ, the chemotactic factors MIP-1β, GM-CSF, the angiogenic mediator VEGF and also of the immuno-modulatory cytokine IL-1ra (p < 0.05). Correlation studies demonstrated also the existence of a significant positive association between the levels of these mediators, evidencing that they are simultaneously regulated in response to the virus. Conclusions Severe respiratory disease caused by the 2009 pandemic influenza virus is characterized by the existence of a direct association between viral replication and host cytokine response, revealing a potential pathogenic link with the severe disease caused by other influenza subtypes such as H5N1.
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- 2011
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40. Bronchoscopy for diagnosis of ventilator-associated pneumonia
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Martin-Loeches, Ignacio, Chastre, Jean, and Wunderink, Richard G.
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Bacterial pneumonia -- Diagnosis -- Development and progression ,Pneumonia -- Diagnosis -- Development and progression ,Bronchoscopy ,Health care industry - Abstract
Author(s): Ignacio Martin-Loeches [sup.1] [sup.2], Jean Chastre [sup.3] [sup.4], Richard G. Wunderink [sup.5] Author Affiliations: (1) grid.416409.e, 0000 0004 0617 8280, Department of Intensive Care Medicine, Multidisciplinary Intensive Care Research [...]
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- 2023
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41. A multi-country analysis of COVID-19 hospitalizations by vaccination status
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Abdukahil, Sheryl Ann, Jabal, Kamal Abu, Salah, Nashat Abu, Airlangga, Eka, Hssain, Ali Ait, Akwani, Chika, Al Qasim, Eman, Alberti, Angela, Aldabbourosama, Osama, Alessi, Marta, Alex, Beatrice, Al-Fares, Abdulrahman, Aliudin, Jeffrey, Alkahlout, Mohammed, Almasri, Lana, Al-Saba’a, Yousef, Alves, Rita, Cabrita, Joana Alves, Amaral, Maria, Ampaw, Phoebe, Anchan, Aditya John, Angheben, Andrea, Arabi, Yaseen, Arcadipane, Antonio, Archambault, Patrick, Arenz, Lukas, Arora, Rakesh, Ashley, Elizabeth A., Atique, Anika, Atlowly, Moad, Bach, Benjamin, Baillie, John Kenneth, Baird, J. Kevin, Balan, Valeria, Barbalho, Renata, Barbosa, Nicholas Yuri, Barclay, Wendy S., Barnikel, Michaela, Beer, Netta, Begum, Husna, Bellemare, David, Beltrame, Anna, Bertoli, Giulia, Bianco, Claudia, Humaid, Felwa Bin, Bitton, Jonathan, Blier, Catherine, Bogaert, Debby, Borges, Diogo, Bouhmani, Dounia, Bounphiengsy, Thipsavanh, Bountthasavong, Latsaniphone, Klerk, Bianca Boxma-de, Monteiro, Filipa Brás, Brazzi, Luca, Buchtele, Nina, Buonsenso, Danilo, Burrell, Aidan, Bustos, Ingrid G., Cabrita, Joana, Caceres, Eder, Garcês, Rui Caetano, Campisi, Josie, Canepa, Cecilia, Caoili, Janice, Cardellino, Chiara Simona, Cardoso, Filipa, Cardoso, Filipe, Cardoso, Sofia, Carney, Gayle, Carrier, François Martin, Carson, Gail, Cascão, Mariana, Casimiro, José, Castañeda, Silvia, Castanheira, Nidyanara, Cattaneo, Paolo, Cavalin, Roberta, Cavayas, Alexandros, Cevik, Muge, Chaleunphon, Bounthavy, Chan, Adrienne, Chand, Meera, Chen, Anjellica, Cheng, Matthew Pellan, Chommanam, Danoy, Chow, Yock Ping, Christy, Nathaniel, Claure-Del Granado, Rolando, Clohisey, Sara, Codan, Cassidy, Connor, Marie, Cooke, Graham S., Copland, Mary, Corley, Amanda, Cortegiani, Andrea, Crowl, Gloria, Cruz, Claudina, Csete, Marc, Custodio, Paula, da Silva Filipe, Ana, Dagens, Andrew, Daley, Peter, Dalloul, Zaina, Dalton, Heidi, Dalton, Jo, Damas, Juliana, Daneman, Nick, Dankwa, Emmanuelle A., Dantas, Jorge, D'Aragon, Frédérick, De Rose, Cristina, de Silva, Thushan, Dechert, William, Denis, Emmanuelle, Dishon, Yael, k Dhangar, Docherty, Annemarie B., Donnelly, Christl A., Donohue, Chloe, Douangdala, Phouvieng, Douglas, James Joshua, Downer, Triona, Downing, Mark, Drake, Thomas, Dryden, Murray, Dubot-Pérès, Audrey, Dudman, Susanne, Dunning, Jake, Duplaix, Mathilde, Durham, Lucian, III, Dyrhol-Riise, Anne Margarita, Edelstein, Michael, Escher, Martina, Esperatti, Mariano, Santo, Catarina Espírito, Estevão, João, Faheem, Amna, Fairfield, Cameron J., Faria, Pedro, Farshait, Nataly, Fernandes, Jorge, Fernandes, Marília Andreia, Ferrão, Joana, Ferraz, Mário, Ferreira, Bernardo, Figueiredo-Mello, Claudia, Fletcher, Tom, Flynn, Brigid, Fontela, Patricia, Forsyth, Simon, Foti, Giuseppe, Fowler, Robert A., Franch-Llasat, Diego, Fraser, Christophe, Fraser, John F., Ribeiro, Ana Freitas, Friedrich, Caren, Fuentes, Nora, G, Argin, Skeie, Linda Gail, Gamble, Carrol, Garcês, Rui, Garcia-Diaz, Julia, Garcia-Gallo, Esteban, Gavin, Aisling, Germano, Nuno, Ghadimi, Moji, Ghisulal, Praveen Kumar, Giani, Marco, Gibson, Jess, Girvan, Michelle, Goco, Geraldine, Gómez-Junyent, Joan, Grable, Margarite, Green, Christopher A., Greenhalf, William, Griffiths, Fiona, Gruner, Heidi, Gu, Yusing, Guerguerian, Anne-Marie, Guerreiro, Daniela, Haber, Daniel, Habraken, Hannah, Hafez, Wael, Hall, Matthew, Halpin, Sophie, Hamdan, Shaher, Hamers, Raph L., Hamza, Summer, Hardwick, Hayley, Harrison, Janet, Hartman, Alan, Heggelund, Lars, Hendry, Ross, Hennessy, Martina, Hesstvedt, Liv, Higgins, Dawn, Higgins, Rupert, Hinton, Samuel, Ho, Antonia, Holter, Jan Cato, Horcajada, Juan Pablo, Ming-Yang Hsu, Jimmy, Hurd, Abby, Ijaz, Samreen, Illana, Carlos Cañada, Inácio, Hugo, Ippolito, Mariachiara, Isidoro, Tiago, Jaber, Hamza, Jackson, Clare, Jaworsky, Denise, Jenum, Synne, Jouvet, Philippe, Kalicinska, Alina, Kandel, Chris, Katz, Kevin, Kaur, Aasmine, Keating, Seán, Kelly, Andrea, Kelly, Sadie, Kennon, Kalynn, Keomany, Sommay, Khalid, Imrana, Kho, Michelle E., Khoo, Saye, Kiiza, Peter, Granerud, Beathe Kiland, Kildal, Anders Benjamin, Klenerman, Paul, Bekken, Gry Kloumann, Knight, Stephen R., Korten, Volkan, Kosgei, Caroline, Kumar, Deepali, Kutsogiannis, Demetrios, Lamontagne, François, Lanza, Marina, Law, Andrew, Law, Andy, Lawrence, Teresa, Lee, James, Lee, Jennifer, Lee, Todd C., Leeming, Gary, Letizia, Andrew, Bassi, Gianluigi Li, Liang, Janet, Lim, Wei Shen, Lind, Andreas, Lissauer, Samantha, Lopes, Diogo, Lyons, Ruth, Machado, Sara, Majeed, Nimisha Abdul, Manetta, Frank, Sant`Ana Malaque, Ceila Maria, Marquis, Catherine, Marsh, Laura, Marshall, John, Martín-Quiros, Alejandro, Martins, Ana, Rego, Caroline Martins, Martucci, Gennaro, Maslove, David, Matthew, Christina, Mayxay, Mayfong, McArthur, Colin, McCarthy, Anne, McConnochie, Rachael, McDonald, Sarah E., McGeer, Allison, McKay, Chris, McLean, Kenneth A., Menon, Kusum, Mentzer, Alexander J., Mesquita, António, Meyer, Dan, Meynert, Alison M., Mihelis, Efstathia, Monteiro, Agostinho, Montrucchio, Giorgia, Moore, Sarah, Moore, Shona C., Cely, Lina Morales, Moro, Lucia, Morton, Ben, Mudara, Caroline, Muhaisen, Mo’nes, Müller, Fredrik, Müller, Karl Erik, Munshi, Laveena, Murthy, Srinivas, Mustafa, Dana, Nagpal, Dave, Narasimhan, Mangala, Nasa, Prashant, Nelder, Matthew, Neumann, Emily, Ng, Pauline Yeung, Nichol, Alistair D., Norman, Lisa, Notari, Alessandra, Noursadeghi, Mahdad, Nusantara, Dwi Utomo, Occhipinti, Giovanna, O'Hearn, Katie, Oliveira, Larissa, Ong, David S.Y., Oosthuyzen, Wilna, Openshaw, Peter, Palmarini, Massimo, Panarello, Giovanna, Panda, Prasan Kumar, Parke, Rachael, Patricio, Patricia, Patterson, Lisa, Paul, Mical, Paulos, Jorge, Paxton, William A., Pejkovska, Mare, Pereira, Rui, Petrovic, Michele, Pettersen, Frank Olav, Pharand, Scott, Phonemixay, Ooyanong, Phoutthavong, Soulichanya, de Piero, Maria, Pimentel, Carlos, Pires, Catarina, Pitaloka, Ayodhia, Pius, Riinu, Poli, Sergio, Pollakis, Georgios, Post, Andra-Maris, Póvoas, Diana, Powis, Jeff, Praphasiri, Viladeth, Pritchard, Mark G., Semedi, Bambang Pujo, Purcell, Gregory, Quesada, Luisa, Quist-Paulsen, Else, Rafael, Aldo, Rahardjani, Mutia, Ramalho, José, Rangappa, Rajavardhan, Rätsep, Indrek, Reeve, Brenda, Reikvam, Dag Henrik, Ren, Hongru, Rewa, Oleksa, Ricchiuto, Antonia, Rishu, Asgar, Rivera Nuñez, Maria Angelica, Roberts, Stephanie, Robertson, David L., Roche-Campo, Ferran, Rodari, Paola, Roessler, Bernhard, Rossanese, Andrea, Rossetti, Matteo, Russell, Clark D., Holten, Aleksander Rygh, Saba, Isabela, Sadat, Musharaf, Sahraei, Valla, Salazar, Leonardo, Sales, Gabriele, Sanchez, Emely, Sancho-Shimizu, Vanessa, Sandhu, Gyan, Sandulescu, Oana, Santos, Marlene, Sarfo-Mensah, Shirley, Sarmiento, Iam Claire E., Saviciute, Egle, Schaffer, Justin, Schwameis, Michael, Schwartz, Gary, Scott, Janet T., Scott-Brown, James, Semple, Malcolm G., Sequeira, Tânia, Shadowitz, Ellen, Shankar, Anuraj, Shaw, Catherine A., Shaw, Victoria, Mohan Shetty, Dr. Rajesh, Sibounheuang, Bountoy, Sigfrid, Louise, Sillaots, Piret, Sin, Wai Ching, Sinatti, Dario, Singh, Mahendra, Skogen, Vegard, Smith, Sue, Solomon, Joshua, Solomon, Tom, Song, Rima, Spinuzza, Elisabetta, Sriskandan, Shiranee, Staudinger, Thomas, Stecher, Stephanie-Susanne, Steinsvik, Trude, Stiksrud, Birgitte, Streinu-Cercel, Adrian, Streinu-Cercel, Anca, Stuart, David, Subekti, Decy, Suen, Jacky Y., Sultana, Asfia, Summers, Charlotte, Suwarti, Atie, Sztajnbok, Jaques, Tabrizi, Shirin, Taleb, Sara, Tedder, Richard S., Teixeira, João, Tessier-Grenier, Hubert, Thompson, Shaun, Thomson, Emma C., Thorpe, Mathew, Thwaites, Ryan S., Tonby, Kristian, Torre, Marta, Torres Santos-Olmo, Rosario Maria, Turgeon, Alexis F., Turtle, Lance C.W., Tveita, Anders, Twardowski, Pawel, Ullrich, Roman, Uyeki, Timothy M., Valentini, Piero, Val-Flores, Luís, Varrone, Michael, Vidal, José Ernesto, Vieira, César, Villanueva, Joy Ann, Villar, Judit, Villoldo, Andrea, Vitiello, Chiara, Vongsouvath, Manivanh, Wainstein, Marina, Webb, Steve, Wei, Jia, Wesselius, Sanne, Wham, Murray, White, Nicole, Willems, Sue, Williams, Bailey, Williams, Virginie, Wils, Evert-Jan, Wittman, Jessica, Yerkovich, Stephanie, Yiaye, Touxiong, Zahran, Maram, Zambon, Maria, Gonçalves, Bronner P., Jassat, Waasila, Baruch, Joaquín, Hashmi, Madiha, Rojek, Amanda, Dasgupta, Abhishek, Martin-Loeches, Ignacio, Reyes, Luis Felipe, Piubelli, Chiara, Citarella, Barbara Wanjiru, Kartsonaki, Christiana, Lefèvre, Benjamin, López Revilla, José W., Lunn, Miles, Harrison, Ewen M., Kraemer, Moritz U.G., Shrapnel, Sally, Horby, Peter, Bisoffi, Zeno, Olliaro, Piero L., and Merson, Laura
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- 2023
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42. Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial
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Asfar, Pierre, Nay, Mai-Anh, Guitton, Christophe, Quenot, Jean-Pierre, Tran-Van, David, Bohe, Julien, Plantefève, Gaëtan, Nseir, Saadalla, Lefrant, Jean-Yves, Monnet, Xavier, Papazian, Laurent, Vinsonneau, Christophe, Constantin, Jean-Michel, Mebazaa, Alexandre, Oueslati, Haikel, Escudero, Dolores, Martinez Sagasti, Fernando, Piacentini, Enrique, Ramirez Galleymore, Paula, Dugernier, Thierry, Fagnoul, David, Michaux, Isabelle, Seibert, Allan, Reinikainen, Matti, Grøfte, Thorbjørn, Martin-Loeches, Ignacio, Laffey, John, François, Bruno, Lambden, Simon, Fivez, Tom, Gibot, Sebastien, Derive, Marc, Grouin, Jean-Marie, Salcedo-Magguilli, Margarita, Lemarié, Jérémie, De Schryver, Nicolas, Jalkanen, Ville, Hicheur, Tarik, Garaud, Jean-Jacques, Cuvier, Valérie, Ferrer, Ricard, Bestle, Morten, Pettilä, Ville, Mira, Jean-Paul, Bouisse, Camille, Mercier, Emmanuelle, Vermassen, Joris, Huberlant, Vincent, Vinatier, Isabelle, Anguel, Nadia, Levy, Mitchell, and Laterre, Pierre-François
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- 2023
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43. Antimicrobial resistance and outcome in the critically ill patient: An opinion paper
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Leone, Marc, Duclos, Gary, Lakbar, Ines, Martin-Loeches, Ignacio, and Einav, Sharon
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- 2023
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44. Major adverse cardiovascular events (MACE) in patients with severe COVID-19 registered in the ISARIC WHO clinical characterization protocol: A prospective, multinational, observational study
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Reyes, Luis Felipe, Garcia-Gallo, Esteban, Murthy, Srinivas, Fuentes, Yuli V., Serrano, Cristian C., Ibáñez-Prada, Elsa D., Lee, James, Rojek, Amanda, Citarella, Barbara Wanjiru, Gonçalves, Bronner P., Dunning, Jake, Rätsep, Indrek, Viñan-Garces, Andre Emilio, Kartsonaki, Christiana, Rello, Jordi, Martin-Loeches, Ignacio, Shankar-Hari, Manu, Olliaro, Piero L., and Merson, Laura
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- 2023
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45. Surviving Sepsis Campaign: Research Opportunities for Infection and Blood Purification Therapies
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Martin-Loeches, Ignacio, Nunnally, Mark E, Hellman, Judith, Lat, Ishaq, Martin, Greg S, Jog, Sameer, Kesecioglu, Jozef, De Backer, Daniel, Coopersmith, Craig M, Deutschman, Clifford S, Ferrer-Roca, Ricard, Machado, Flavia, and Martin, Greg
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Biomedical and Clinical Sciences ,Clinical Sciences ,Clinical Research ,Infectious Diseases ,Hematology ,Sepsis ,Inflammatory and immune system ,Infection ,infection ,intensive care unit ,sepsis ,septic shock ,ventilator-associated pneumonia ,Clinical sciences - Abstract
Patients with infection can develop sepsis, and their mortality can be high. An important aspect in the treatment of sepsis is adequate management of the infection.Data sourcesUsing a modified Delphi approach, the Surviving Sepsis Campaign research committee recently published a series of 26 priorities for sepsis and septic shock.Study selectionTask force members with specific expertise were tasked with generating expanded reviews for all infection questions and a subset of adjunctive therapy questions from the larger list of sepsis priorities. Each question was addressed by one of the six task force members.Data extractionIn-depth reviews were then edited by the group as a whole, with added input from the committee cochairs.Data synthesisSix questions were addressed: 1) should empiric antibiotic combination therapy be used in sepsis or septic shock? 2) does optimization of antimicrobial pharmacokinetics and pharmacodynamics impact patient outcomes in sepsis? 3) should viral reactivation resulting from sepsis-induced immunosuppression be treated with antiviral therapy in critically ill septic patients? 4) should rapid diagnostic tests be implemented in clinical practice? 5) what is the role of lung-protective ventilation in sepsis patients without acute respiratory distress syndrome? and 6) how do we determine the efficacy of "blood purification" therapies such as endotoxin absorbers, cytokine absorbers, and plasmapheresis.ConclusionsThe research committee members for the Surviving Sepsis Campaign aimed to explore research questions in order to provide existing evidence and highlight areas of uncertainty and future directions.
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- 2021
46. Ventilation practices in burn patients—an international prospective observational cohort study
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Schultz, Marcus J, Horn, Janneke, Hollmann, Markus W, Preckel, Benedikt, Glas, Gerie J, Colpaert, Kirsten, Malbrain, Manu, Neto, Ary Serpa, Asehnoune, Karim, de Abreu, Marcello Gamma, Martin-Loeches, Ignacio, Pelosi, Paolo, Sjöberg, Folke, Binnekade, Jan M, Cleffken, Berry, Juffermans, Nicole P, Knape, Paul, Loef, Bert G, Mackie, David P, Enkhbaatar, Perenlei, Depetris, Nadia, Perner, Anders, Herrero, Eva, Cachafeiro, Lucia, Jeschke, Marc, Lipman, Jeffrey, Legrand, Matthieu, Horter, Johannes, Lavrentieva, Athina, Glas, Gerie, Kazemi, Alex, Guttormsen, Anne Berit, Huss, Frederik, Kol, Mark, Wong, Helen, Starr, Therese, De Crop, Luc, de Oliveira Filho, Wilson, Silva, João Manoel, Grion, Cintia MC, Jeschke, Marc G, Burnett, Marjorie, Mondrup, Frederik, Ravat, Francois, Fontaine, Mathieu, Asehoune, Karim, Le Floch, Renan, Jeanne, Mathieu, Bacus, Morgane, Chaussard, Maïté, Lehnhardt, Marcus, Mikhail, Bassem Daniel, Gille, Jochen, Sharkey, Aidan, Trommel, Nicole, Reidinga, Auke C, Vieleers, Nadine, Tilsley, Anna, Onarheim, Henning, Bouza, Maria Teresa, Agrifoglio, Alexander, Fredén, Filip, Palmieri, Tina, Painting, Lynda E, and investigators, LAMiNAR
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Paediatrics ,Biomedical and Clinical Sciences ,Physical Injury - Accidents and Adverse Effects ,Clinical Research ,Lung ,Respiratory ,Mechanical ventilation ,Inhalation trauma ,Lung-protective ,Critical care ,LAMiNAR investigators ,Clinical sciences ,Medical biotechnology ,Biomedical engineering - Abstract
BackgroundIt is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28).MethodsThis is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V T) was defined as V T ≤ 8 mL/kg predicted body weight (PBW). Levels of positive end-expiratory pressure (PEEP) and maximum airway pressures were collected. The association between V T and VFD-28 was analyzed using a competing risk model. Ventilation settings were presented for all patients, focusing on the first day of ventilation. We also compared ventilation settings between patients with and without inhalation trauma.ResultsA total of 160 patients from 28 ICUs in 16 countries were included. Low V T was used in 74% of patients, median V T size was 7.3 [interquartile range (IQR) 6.2-8.3] mL/kg PBW and did not differ between patients with and without inhalation trauma (p = 0.58). Median VFD-28 was 17 (IQR 0-26), without a difference between ventilation with low or high V T (p = 0.98). All patients were ventilated with PEEP levels ≥5 cmH2O; 80% of patients had maximum airway pressures
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- 2021
47. Guidelines for the management of severe community-acquired pneumonia: one confusing recommendation. Author’s reply
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Martin-Loeches, Ignacio, Nagavci, Blin, and Torres, Antoni
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- 2023
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48. Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19
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Abdukahil, heryl Ann, Abdulkadir, Nurul Najmee, Abe, Ryuzo, Abel, Laurent, Abrous, Amal, Absil, Lara, Acker, Andrew, Adachi, Shingo, Adrião, Diana, Al Ageel, Saleh, Ahmed, Shakeel, Ainscough, Kate, Airlangga, Eka, Aisa, Tharwat, Hssain, Ali Ait, Tamlihat, Younes Ait, Akimoto, Takako, Akmal, Ernita, Akwani, Chika, Al Qasim, Eman, Alalqam, Razi, Alberti, Angela, Al-dabbous, Tala, Alegesan, Senthilkumar, Alessi, Marta, Alex, Beatrice, Alexandre, Kévin, Al-Fares, Abdulrahman, Alfoudri, Huda, Ali, Imran, Alidjnou, Kazali Enagnon, Aliudin, Jeffrey, Alkhafajee, Qabas, Allavena, Clotilde, Allou, Nathalie, Alves, João, Alves, Rita, Alves, João Melo, Cabrita, Joana Alves, Amaral, Maria, Amira, Nur, Ampaw, Phoebe, Andini, Roberto, Andréjak, Claire, Angheben, Andrea, Angoulvant, François, Ansart, Séverine, Anthonidass, Sivanesen, Antonelli, Massimo, Antunes de Brito, Carlos Alexandre, Apriyana, Ardiyan, Arabi, Yaseen, Aragao, Irene, Arancibia, Francisco, Araujo, Carolline, Arcadipane, Antonio, Archambault, Patrick, Arenz, Lukas, Arlet, Jean-Benoît, Arnold-Day, Christel, Arora, Lovkesh, Arora, Rakesh, Artaud-Macari, Elise, Aryal, Diptesh, Asensio, Angel, Ashraf, Muhammad, Assie, Jean Baptiste, Asyraf, Amirul, Atif, Minahel, Atique, Anika, Auchabie, Johann, Aumaitre, Hugues, Auvet, Adrien, Azemar, Laurène, Azoulay, Cecile, Bach, Benjamin, Bachelet, Delphine, Badr, Claudine, Baillie, J. Kenneth, Baird, J Kevin, Bak, Erica, Bakakos, Agamemnon, Bakar, Nazreen Abu, Bal, Andriy, Balakrishnan, Mohanaprasanth, Balan, Valeria, Bani-Sadr, Firouzé, Barbalho, Renata, Barbosa, Nicholas Yuri, Barclay, Wendy S., Barnett, Saef Umar, Barnikel, Michaela, Barrelet, Audrey, Barrigoto, Cleide, Bartoli, Marie, Baruch, Joaquín, Basmaci, Romain, Hassin Basri, Muhammad Fadhli, Battaglini, Denise, Bauer, Jules, Bautista Rincon, Diego Fernando, Beane, Abigail, Bedossa, Alexandra, Bee, Ker Hong, Begum, Husna, Behilill, Sylvie, Beishuizen, Albertus, Beljantsev, Aleksandr, Bellemare, David, Beltrame, Anna, Beltrão, Beatriz Amorim, Beluze, Marine, Benech, Nicolas, Benjiman, Lionel Eric, Benkerrou, Dehbia, Bennett, Suzanne, Benny, Binny, Bento, Luís, Berdal, Jan-Erik, Bergeaud, Delphine, Bergin, Hazel, Bernal Sobrino, José Luis, Bertoli, Giulia, Bertolino, Lorenzo, Bessis, Simon, Bevilcaqua, Sybille, Bezulier, Karine, Bhatt, Amar, Bhavsar, Krishna, Bianco, Claudia, Bidin, Farah Nadiah, Singh, Moirangthem Bikram, Humaid, Felwa Bin, Bin Kamarudin, Mohd Nazlin, Bisoffi, Zeno, Bissuel, François, Biston, Patrick, Bitker, Laurent, Bitton, Jonathan, Blanco-Schweizer, Pablo, Blier, Catherine, Bloos, Frank, Blot, Mathieu, Blumberg, Lucille, Boccia, Filomena, Bodenes, Laetitia, Bogaert, Debby, Boivin, Anne-Hélène, Bolaños, Isabela, Bolze, Pierre-Adrien, Bompart, François, Borges, Diogo, Borie, Raphaël, Botelho-Nevers, Elisabeth, Bouadma, Lila, Bouchaud, Olivier, Bouchez, Sabelline, Bouhmani, Dounia, Bouhour, Damien, Bouiller, Kévin, Bouillet, Laurence, Bouisse, Camile, Boureau, Anne-Sophie, Bourke, John, Bouscambert, Maude, Bousquet, Aurore, Bouziotis, Jason, Boxma, Bianca, Boyer-Besseyre, Marielle, Boylan, Maria, Bozza, Fernando Augusto, Braconnier, Axelle, Braga, Cynthia, Monteiro, Filipa Brás, Brazzi, Luca, Breen, Patrick, Breen, Dorothy, Brewster, David, Brickell, Kathy, Browne, Shaunagh, Brusse-Keizer, Marjolein, Bryda, Petra, Buchtele, Nina, Bugaeva, Polina, Buisson, Marielle, Burhan, Erlina, Burrell, Aidan, Bustos, Ingrid G., Butnaru, Denis, Cabie, André, Cabral, Susana, Caceres, Eder, Cadoz, Cyril, Garcês, Rui Caetano, Calligy, Kate, Calvache, Jose Andres, Camões, João, Campana, Valentine, Campbell, Paul, Campisi, Josie, Cantero, Mireia, Caraux-Paz, Pauline, Cardellino, Chiara Simona, Cardoso, Sofia, Cardoso, Filipe, Cardoso, Filipa, Cardoso, Nelson, Carelli, Simone, Carlier, Nicolas, Carmoi, Thierry, Carney, Gayle, Carqueja, Inês, Carret, Marie-Christine, Carrier, François Martin, Carroll, Ida, Carson, Gail, Casanova, Maire-Laure, Cascão, Mariana, Casey, Siobhan, Casimiro, José, Cassandra, Bailey, Castanheira, Nidyanara, Castor-Alexandre, Guylaine, Castro, Ivo, Catarino, Ana, Catherine, François-Xavier, Cattaneo, Paolo, Cavalin, Roberta, Cavayas, Alexandros, Cervantes-Gonzalez, Minerva, Chair, Anissa, Chakveatze, Catherine, Chan, Adrienne, Chand, Meera, Chantalat Auger, Christelle, Chapplain, Jean-Marc, Charpentier, Charlotte, Chas, Julie, Chávez Iñiguez, Jonathan Samuel, Chen, Anjellica, Chen, Yih-Sharng, Chenard, Léo, Cheng, Matthew Pellan, Cheret, Antoine, Chiarabini, Thibault, Chica, Julian, Chidambaram, Suresh Kumar, Tho, Leong Chin, Chirouze, Catherine, Chiumello, Davide, Cho, Sung-Min, Cholley, Bernard, Chopin, Marie-Charlotte, Chow, Ting Soo, Chow, Yock Ping, Chua, Hiu Jian, Chua, Jonathan, Cidade, Jose Pedro, Citarella, Barbara Wanjiru, Ciullo, Anna, Clarke, Jennifer, Claure-Del Granado, Rolando, Clohisey, Sara, Cobb, Perren J., Codan, Cassidy, Cody, Caitriona, Coelho, Alexandra, Coles, Megan, Coles, Jennifer, Colin, Gwenhaël, Collins, Michael, Colombo, Sebastiano Maria, Combs, Pamela, Connolly, Jennifer, Connor, Marie, Conrad, Anne, Conway, Elaine, Cooke, Graham S., Copland, Mary, Cordel, Hugues, Corley, Amanda, Cornelis, Sabine, Cornet, Alexander Daniel, Corpuz, Arianne Joy, Cortegiani, Andrea, Corvaisier, Grégory, Couffignal, Camille, Couffin-Cadiergues, Sandrine, Courtois, Roxane, Cousse, Stéphanie, Croonen, Sabine, Crowl, Gloria, Crump, Jonathan, Cruz, Claudina, Cruz Bermúdez, Juan Luis, Rojo, Jaime Cruz, Csete, Marc, Cullen, Ailbhe, Curley, Gerard, Curlier, Elodie, Curran, Colleen, Custodio, Paula, da Silva Filipe, Ana, Da Silveira, Charlene, Dabaliz, Al-Awwab, Dai, Danyang, Dagens, Andrew, Dahly, Darren, Dalton, Heidi, Dalton, Jo, Daly, Seamus, Damas, Juliana, Daneman, Nick, Daniel, Corinne, Dankwa, Emmanuelle A., Dantas, Jorge, de Loughry, Gillian, De Montmollin, Etienne, Freitas de Oliveira França, Rafael, De Rosa, Rosanna, de Silva, Thushan, de Vries, Peter, Dean, David, Debard, Alexa, DeBenedictis, Bianca, Debray, Marie-Pierre, DeCastro, Nathalie, Dechert, William, Deconninck, Lauren, Decours, Romain, Defous, Eve, Delacroix, Isabelle, Delaveuve, Eric, Delavigne, Karen, Dell'Amore, Andrea, Delmas, Christelle, Delobel, Pierre, Delsing, Corine, Demonchy, Elisa, Denis, Emmanuelle, Deplanque, Dominique, Depuydt, Pieter, Desai, Mehul, Descamps, Diane, Desvallées, Mathilde, Dewayanti, Santi, Dhanger, Pathik, Diallo, Alpha, Diamantis, Sylvain, Da Silva, Fernanda Dias, Diaz, Juan Jose, Diaz, Rodrigo, Didier, Kévin, Diehl, Jean-Luc, Dieperink, Wim, Dimet, Jérôme, Dinot, Vincent, Diop, Fara, Diouf, Alphonsine, Dishon, Yael, Djossou, Félix, Docherty, Annemarie B., Doherty, Helen, Donnelly, Maria, Donnelly, Christl A., Donohue, Sean, Donohue, Yoann, Donohue, Chloe, Doran, Peter, Dorival, Céline, D'Ortenzio, Eric, Douglas, James Joshua, Dournon, Nathalie, Downer, Triona, Downey, Joanne, Downing, Mark, Drake, Tom, Driscoll, Aoife, Dryden, Murray, Fonseca, Claudio Duarte, Dubee, Vincent, Dubos, François, Ducancelle, Alexandre, Duculan, Toni, Dudman, Susanne, Duggal, Abhijit, Dunand, Paul, Dunning, Jake, Duplaix, Mathilde, Durante-Mangoni, Emanuele, Durham, Lucian, III, Dussol, Bertrand, Duthoit, Juliette, Duval, Xavier, Dyrhol-Riise, Anne Margarita, Ean, Sim Choon, Echeverria-Villalobos, Marco, Edwards, Eleanor, Egan, Siobhan, El Sanharawi, Mohammed, Elapavaluru, Subbarao, Elharrar, Brigitte, Eloy, Philippine, Elshazly, Tarek, Enderle, Isabelle, Endo, Tomoyuki, Eng, Chan Chee, Engelmann, Ilka, Enouf, Vincent, Epaulard, Olivier, Escher, Martina, Esperatti, Mariano, Esperou, Hélène, Santo, Catarina Espírito, Esposito-Farese, Marina, Estevão, João, Etienne, Manuel, Ettalhaoui, Nadia, Everding, Anna Greti, Evers, Mirjam, Fabre, Marc, Fabre, Isabelle, Faheem, Amna, Fahy, Arabella, Fairfield, Cameron J., Faria, Pedro, Fateena, Hanan, Fatoni, Arie Zainul, Faure, Karine, Favory, Raphaël, Fayed, Mohamed, Feely, Niamh, Feeney, Laura, Fernandes, Jorge, Fernandes, Marília Andreia, Fernandes, Susana, Ferrand, François-Xavier, Devouge, Eglantine Ferrand, Ferrão, Joana, Ferraz, Mário, Ferreira, Sílvia, Ferreira, Bernardo, Ferreira, Benigno, Ferriere, Nicolas, Ficko, Céline, Figueiredo-Mello, Claudia, Fiorda, Juan, Flament, Thomas, Flanagan, Emily, Flateau, Clara, Fletcher, Tom, Florence, Aline-Marie, Florio, Letizia Lucia, Flynn, Deirdre, Foley, Jean, Fomin, Victor, Fonseca, Tatiana, Forsyth, Simon, Foster, Denise, Foti, Giuseppe, Fourn, Erwan, Fowler, Robert A., Fraher, Marianne, Franch-Llasat, Diego, Fraser, John F., Fraser, Christophe, Freire, Marcela Vieira, Ribeiro, Ana Freitas, Friedrich, Caren, Fritz, Ricardo, Fry, Stéphanie, Fuentes, Nora, Fukuda, Masahiro, G, Argin, Gaborieau, Valérie, Gaci, Rostane, Gagliardi, Massimo, Gagnard, Jean-Charles, Gagneux-Brunon, Amandine, Gaião, Sérgio, Skeie, Linda Gail, Gallagher, Phil, Gamble, Carrol, Gani, Yasmin, Garan, Arthur, Garcia, Rebekha, Barrio, Noelia García, Garcia-Gallo, Esteban, Garot, Denis, Garrait, Valérie, Gault, Nathalie, Gavin, Aisling, Gavrylov, Anatoliy, Gaymard, Alexandre, Gebauer, Johannes, Geraud, Eva, Morlaes, Louis Gerbaud, Germano, Nuno, Ghosn, Jade, Giani, Marco, Gibson, Jess, Gigante, Tristan, Gilg, Morgane, Gilroy, Elaine, Giordano, Guillermo, Girvan, Michelle, Gissot, Valérie, Glikman, Daniel, Glybochko, Petr, Gnall, Eric, Goehringer, François, Goffard, Jean-Christophe, Goh, Jin Yi, Golob, Jonathan, Gominet, Marie, Gonzalez, Alicia, Gordon, Patricia, Gorenne, Isabelle, Gormley, Conor, Goubert, Laure, Goujard, Cécile, Goulenok, Tiphaine, Grable, Margarite, Grandin, Edward Wilson, Granier, Pascal, Grasselli, Giacomo, Green, Christopher A., Greenhalf, William, Greffe, Segolène, Grieco, Domenico Luca, Griffee, Matthew, Griffiths, Fiona, Grigoras, Ioana, Groenendijk, Albert, Gruner, Heidi, Gu, Yusing, Guedj, Jérémie, Guego, Martin, Guellec, Dewi, Guerreiro, Daniela, Guery, Romain, Guillaumot, Anne, Guilleminault, Laurent, Guimarães de Castro, Maisa, Guimard, Thomas, Haalboom, Marieke, Haber, Daniel, Habraken, Hannah, Hachemi, Ali, Hadri, Nadir, Hakak, Sheeba, Hall, Adam, Hall, Matthew, Halpin, Sophie, Hamer, Ansley, Hamers, Raph L., Hamidfar, Rebecca, Hammond, Terese, Hammond, Naomi, Han, Lim Yuen, Hao, Kok Wei, Hardwick, Hayley, Harrison, Ewen M., Harrison, Janet, Hartman, Alan, Hashmi, Junaid, Hayes, Ailbhe, Hays, Leanne, Heerman, Jan, Heggelund, Lars, Hendry, Ross, Hennessy, Martina, Hentzien, Maxime, Hernandez, Diana, Hershey, Andrew, Hesstvedt, Liv, Higgins, Eibhlin, Higgins, Dawn, Higgins, Rupert, Hinchion, Rita, Hinton, Samuel, Hiraiwa, Hiroaki, Hitoto, Hikombo, Ho, Antonia, Ho, Yi Bin, Hoctin, Alexandre, Hoffmann, Isabelle, Hoh, Wei Han, Hoiting, Oscar, Holt, Rebecca, Holter, Jan Cato, Horby, Peter, Hoshino, Kota, Houas, Ikram, Hough, Catherine L., Houltham, Stuart, Ming-Yang Hsu, Jimmy, Hulot, Jean-Sébastien, Hurd, Abby, Ijaz, Samreen, Ikram, M. Arfan, Illes, Hajnal-Gabriela, Imbert, Patrick, Inácio, Hugo, Ing, Yun Sii, Ippolito, Mariachiara, Isgett, Sarah, Isidoro, Tiago, Ismail, Nadiah, Isnard, Margaux, Itai, Junji, Ivulich, Daniel, Jaafar, Danielle, Jaafoura, Salma, Jabot, Julien, Jackson, Clare, Jaquet, Pierre, Jassat, Waasila, Jaud-Fischer, Coline, Jaureguiberry, Stéphane, Jego, Florence, Jelani, Anilawati Mat, Jenum, Synne, Joe, Ong Yiaw, Jorge García, Ruth N., Joseph, Mark, Joseph, Cédric, Jourdain, Mercé, Jouvet, Philippe, Jung, Anna, Juzar, Dafsah, Kafif, Ouifiya, Kaguelidou, Florentia, Kaisbain, Neerusha, Kaleesvran, Thavamany, Kali, Sabina, Kalomoiri, Smaragdi, Ayadi Kamaluddin, Muhammad Aisar, Che Kamaruddin, Zul Amali, Kamarudin, Nadiah, Kandamby, Darshana Hewa, Kandel, Chris, Kang, Kong Yeow, Karpayah, Pratap, Kartsonaki, Christiana, Kasugai, Daisuke, Kataria, Anant, Katz, Kevin, Kaur, Aasmine, Kay, Christy, Kayyali, Lamees, Keating, Seán, Kelly, Claire, Kelly, Yvelynne, Kelly, Andrea, Kelly, Niamh, Kelly, Aoife, Kelly, Sadie, Kelsey, Maeve, Kennedy, Ryan, Kennon, Kalynn, Kernan, Maeve, Kerroumi, Younes, Keshav, Sharma, Khalid, Imrana, Khalil, Antoine, Khan, Coralie, Khan, Irfan, Kho, Michelle E., Khoo, Saye, Khoo, Ryan, Khoo, Denisa, Kiat, Khor How, Kida, Yuri, Kiiza, Peter, Granerud, Beathe Kiland, Kildal, Anders Benjamin, Kim, Jae Burm, Kimmoun, Antoine, Kitamura, Nobuya, Klenerman, Paul, Klont, Rob, Bekken, Gry Kloumann, Knight, Stephen R., Komatsu, Mamoru, Korten, Volkan, Kpangon, Arsène, Krawczyk, Karolina, Krishnan, Sudhir, Krishnan, Vinothini, Kruglova, Oksana, Kumar, Deepali, Kumar, Ganesh, Tirupakuzhi Vijayaraghavan, Bharath Kumar, Vecham, Pavan Kumar, Kuriakose, Dinesh, Kurtzman, Ethan, Kutsogiannis, Demetrios, Kutsyna, Galyna, Kyriakoulis, Konstantinos, Lachatre, Marie, Lacoste, Marie, Laffey, John G., Lafhej, Nadhem, Lagrange, Marie, Laine, Fabrice, Lairez, Olivier, Lalueza, Antonio, Lambert, Marc, Langelot-Richard, Marie, Langlois, Vincent, Lantang, Eka Yudha, Lanza, Marina, Laouénan, Cédric, Laribi, Samira, Lariviere, Delphine, Lasry, Stéphane, Launay, Odile, Laureillard, Didier, Lavie-Badie, Yoan, Law, Andy, Lawrence, Teresa, Lawrence, Cassie, Le, Minh, Le Bihan, Clément, Le Bris, Cyril, Le Falher, Georges, Le Fevre, Lucie, Le Hingrat, Quentin, Le Maréchal, Marion, Le Mestre, Soizic, Le Moal, Gwenaël, Le Moing, Vincent, Le Nagard, Hervé, Le Turnier, Paul, Lee, Todd C., Lee, Su Hwan, Lee, James, Lee, Jennifer, Lee, Heng Gee, Lee, Biing Horng, Lee, Yi Lin, Leeming, Gary, Lefebvre, Laurent, Lefebvre, Bénédicte, Lefèvre, Benjamin, LeGac, Sylvie, Lelievre, Jean-Daniel, Lellouche, François, Lemaignen, Adrien, Lemee, Véronique, Lemeur, Anthony, Lemmink, Gretchen, Lene, Ha Sha, Leone, Michela, Leone, Marc, Lepiller, Quentin, Lescure, François-Xavier, Lesens, Olivier, Lesouhaitier, Mathieu, Lester-Grant, Amy, Letrou, Sophie, Levy, Yves, Levy, Bruno, Levy-Marchal, Claire, L'Her, Erwan, Bassi, Gianluigi Li, Liang, Janet, Liegeon, Geoffrey, Lim, Wei Shen, Lim, Kah Chuan, Lima, Chantre, Lina, Bruno, Lina, Lim, Lind, Andreas, Lingas, Guillaume, Lion-Daolio, Sylvie, Liu, Keibun, Livrozet, Marine, Lizotte, Patricia, Lolong, Navy, Loon, Leong Chee, Lopes, Diogo, Lopez-Colon, Dalia, Loschner, Anthony L., Loubet, Paul, Loufti, Bouchra, Louis, Guillame, Lourenco, Silvia, Low, Lee, Lowik, Marije, Loy, Jia Shyi, Lucet, Jean Christophe, Bermejo, Carlos Lumbreras, Luna, Carlos M., Lungu, Olguta, Lunn, Miles, Luong, Liem, Luque, Nestor, Luton, Dominique, Lyons, Ruth, Maasikas, Olavi, Mabiala, Oryane, Machado, Sara, Machado, Moïse, Macheda, Gabriel, Madiha, Hashmi, Maestro de la Calle, Guillermo, Mahieu, Rafael, Mahy, Sophie, Maier, Lars S., Maillet, Mylène, Maitre, Thomas, Malfertheiner, Maximilian, Malik, Nadia, Mallon, Paddy, Malvy, Denis, Manda, Victoria, Mandelbrot, Laurent, Manetta, Frank, Mankikian, Julie, Manning, Edmund, Manuel, Aldric, Sant`Ana Malaque, Ceila Maria, Marino, Flávio, Markowicz, Samuel, Marques, Ana, Marsh, Brian, Marsh, Laura, Marshal, Megan, Marshall, John, Martelli, Celina Turchi, Martin, Emily, Martin-Blondel, Guillaume, Martinez, F. Eduardo, Martin-Loeches, Ignacio, Martinot, Martin, Martins, João, Martins, Ana, Rego, Caroline Martins, Martucci, Gennaro, Martynenko, Olga, Marwali, Eva Miranda, Marzukie, Marsilla, Maslove, David, Mason, Sabina, Mat Nor, Mohd Basri, Matan, Moshe, Mathieu, Daniel, Mattei, Mathieu, Maulin, Laurence, Maxwell, Michael, Mazzoni, Thierry, Sweeney, Lisa Mc, McArthur, Colin, McCanny, Peter, McCarthy, Anne, McCarthy, Aine, McCloskey, Colin, McConnochie, Rachael, McDermott, Sherry, McDonald, Sarah E., McElroy, Aine, McElwee, Samuel, McEneany, Victoria, McEvoy, Natalie, McGeer, Allison, McKay, Chris, McKeown, Johnny, McLean, Kenneth A., McNicholas, Bairbre, McPartlan, Elaine, Meaney, Edel, Mear-Passard, Cécile, Mechlin, Maggie, Mehkri, Omar, Mele, Ferruccio, Menon, Kusum, Mentré, France, Mentzer, Alexander J., Mercier, Noémie, Mercier, Emmanuelle, Merckx, Antoine, Mergeay-Fabre, Mayka, Mergler, Blake, Merson, Laura, Mesquita, António, Metwally, Osama, Meybeck, Agnès, Meyer, Dan, Meynert, Alison M., Meysonnier, Vanina, Meziane, Amina, Mezidi, Mehdi, Michelanglei, Céline, Michelet, Isabelle, Mihelis, Efstathia, Mihnovit, Vladislav, Miller, Jennene, Misnan, Nor Arisah, Mohamed, Tahira Jamal, Eliza Mohamed, Nik Nur, Moin, Asma, Molinos, Elena, Molloy, Brenda, Monahan, Sinead, Mone, Mary, Monteiro, Agostinho, Montes, Claudia, Montrucchio, Giorgia, Moore, Shona C., Moore, Sarah, Cely, Lina Morales, Moro, Lucia, Motherway, Catherine, Motos, Ana, Mouquet, Hugo, Perrot, Clara Mouton, Moyet, Julien, Mudara, Caroline, Muh, Ng Yong, Muhamad, Dzawani, Mullaert, Jimmy, Müller, Fredrik, Müller, Karl Erik, Munblit, Daniel, Murphy, Aisling, Murphy, Lorna, Murray, Patrick, Murris, Marlène, Murthy, Srinivas, Musaab, Himed, Muyandy, Gugapriyaa, Myrodia, Dimitra Melia, Nagpal, Dave, Nagrebetsky, Alex, Narasimhan, Mangala, Narayanan, Nageswaran, Neant, Nadège, Necsoi, Coca, Nekliudov, Nikita, Neto, Raul, Neumann, Emily, Ng, Pauline Yeung, Ng, Wing Yiu, Nghi, Anthony, Nguyen, Duc, Choileain, Orna Ni, Leathlobhair, Niamh Ni, Nichol, Alistair D., Nitayavardhana, Prompak, Nonas, Stephanie, Mohd Noordin, Nurul Amani, Noret, Marion, Izzati Norharizam, Nurul Faten, Norman, Lisa, Notari, Alessandra, Noursadeghi, Mahdad, Nseir, Saad, Nusantara, Dwi Utomo, Nyamankolly, Elsa, Brien, Fionnuala O., Callaghan, Annmarie O., O'Callaghan, Annmarie, Occhipinti, Giovanna, OConnor, Derbrenn, Ogura, Takayuki, O'Halloran, Sophie, O'Hearn, Katie, Ohshimo, Shinichiro, Oliveira, João, Olliaro, Piero L., O'Neil, Conar, Ong, David S.Y., Ong, Jee Yan, Oosthuyzen, Wilna, Opavsky, Anne, Openshaw, Peter, Orozco-Chamorro, Claudia Milena, Ortoleva, Jamel, Osatnik, Javier, O'Shea, Linda, O'Sullivan, Miriam, Othman, Siti Zubaidah, Ouamara, Nadia, Ouissa, Rachida, Oziol, Eric, Pagadoy, Maïder, Pages, Justine, Palmarini, Massimo, Panarello, Giovanna, Panda, Prasan Kumar, Pang, Lai Hui, Panigada, Mauro, Pansu, Nathalie, Papadopoulos, Aurélie, Parke, Rachael, Pasquier, Jérémie, Pastene, Bruno, Patauner, Fabian, Pathmanathan, Mohan Dass, Patricio, Patricia, Patrier, Juliette, Patterson, Lisa, Paul, Mical, Paul, Christelle, Paulos, Jorge, Paxton, William A., Payen, Jean-François, Peake, Sandra L., Peariasamy, Kalaiarasu, Jiménez, Miguel Pedrera, Peek, Giles J., Peelman, Florent, Peiffer-Smadja, Nathan, Peigne, Vincent, Pejkovska, Mare, Pelosi, Paolo, Peltan, Ithan D., Pereira, Rui, Perez, Daniel, Periel, Luis, Perpoint, Thomas, Pesenti, Antonio, Pestre, Vincent, Petrou, Lenka, Petrovic, Michele, Petrov-Sanchez, Ventzislava, Pettersen, Frank Olav, Peytavin, Gilles, Pharand, Scott, Piagnerelli, Michael, Picard, Walter, Picone, Olivier, Pierobon, Carola, Piersma, Djura, Pimentel, Carlos, Piquard, Valentine, Pires, Catarina, Pironneau, Isabelle, Piroth, Lionel, Pitaloka, Ayodhia, Piubelli, Chiara, Pius, Riinu, Plantier, Laurent, Png, Hon Shen, Poissy, Julien, Pokeerbux, Ryadh, Poli, Sergio, Pollakis, Georgios, Ponscarme, Diane, Porto, Diego Bastos, Post, Andra-Maris, Postma, Douwe F., Povoa, Pedro, Póvoas, Diana, Powis, Jeff, Prapa, Sofia, Preau, Sébastien, Prebensen, Christian, Preiser, Jean-Charles, Prinssen, Anton, Proença, Lucia, Pudota, Sravya, Puéchal, Oriane, Semedi, Bambang Pujo, Purcell, Gregory, Quesada, Luisa, González, Víctor Quirós, Quist-Paulsen, Else, Quraishi, Mohammed, Qutishat, Fadi, Rabaud, Christian, Rafael, Aldo, Rafiq, Marie, Rahardjani, Mutia, Rahimi, Amir Kamel, Rahman, Rozanah Abd, Haji Ab Rahman, Ahmad Kashfi, Rainieri, Fernando, Rajahram, Giri Shan, Ramakrishnan, Nagarajan, Ramalho, José, Ramli, Ahmad Afiq, Rammaert, Blandine, Ramos, Grazielle Viana, Ranjan, Ritika, Rapp, Christophe, Rasmin, Menaldi, Rätsep, Indrek, Ravi, Tharmini, Real, Andre, Rebaudet, Stanislas, Redl, Sarah, Reeve, Brenda, Reid, Liadain, Reikvam, Dag Henrik, Reis, Renato, Remy, Martine, Ren, Hongru, Resseguier, Anne-Sophie, Revest, Matthieu, Rewa, Oleksa, Reyes, Tiago, Reyes, Luis Felipe, Ribeiro, Maria Ines, Richardson, David, Richardson, Denise, Richier, Laurent, Atikah Ahmad Ridzuan, Siti Nurul, Rios, Ana L., Rishu, Asgar, Rispal, Patrick, Risso, Karine, Rizer, Nicholas, Robba, Chiara, Roberto, André, Roberts, Stephanie, Robertson, David L., Robineau, Olivier, Roche-Campo, Ferran, Rodari, Paola, Rodeia, Simão, Roessler, Bernhard, Roger, Pierre-Marie, Rojek, Amanda, Romaru, Juliette, Roncon-Albuquerque, Roberto, Jr., Roriz, Mélanie, Rosa-Calatrava, Manuel, Rose, Michael, Rosenberger, Dorothea, Rossanese, Andrea, Rossetti, Matteo, Rossignol, Bénédicte, Rossignol, Patrick, Rousset, Stella, Roy, Carine, Roze, Benoît, Russell, Clark D., Ryan, Maria, Ryan, Maeve, Ryckaert, Steffi, Holten, Aleksander Rygh, Saba, Isabela, Sadat, Musharaf, Sahraei, Valla, Saint-Gilles, Maximilien, Sakiyalak, Pranya, Salazar, Leonardo, Sales, Gabriele, Sallaberry, Stéphane, Gandonniere, Charlotte Salmon, Salvator, Hélène, Sanchez, Emely, Sanchez, Olivier, Sanchez-Miralles, Angel, Sancho-Shimizu, Vanessa, Sandhu, Gyan, Sandhu, Zulfiqar, Sandrine, Pierre-François, Sandulescu, Oana, Santos, Marlene, Sarfo-Mensah, Shirley, Sarmiento, Iam Claire E., Sarton, Benjamine, Satyapriya, Sree, Satyawati, Rumaisah, Saviciute, Egle, Saw, Yen Tsen, Schaffer, Justin, Schermer, Tjard, Scherpereel, Arnaud, Schneider, Marion, Schroll, Stephan, Schwameis, Michael, Scott, Janet T., Scott-Brown, James, Sedillot, Nicholas, Seitz, Tamara, Selvarajoo, Mageswari, Semaille, Caroline, Semple, Malcolm G., Senian, Rasidah Bt, Senneville, Eric, Sepulveda, Claudia, Sequeira, Filipa, Sequeira, Tânia, Neto, Ary Serpa, Balazote, Pablo Serrano, Shadowitz, Ellen, Shahidan, Syamin Asyraf, Shamsah, Mohammad, Shankar, Anuraj, Sharjeel, Shaikh, Sharma, Pratima, Shaw, Catherine A., Shaw, Victoria, Sheenan, John Robert, Shi, Haixia, Shime, Nobuaki, Shimizu, Hiroaki, Shimizu, Keiki, Shrapnel, Sally, Shum, Hoi Ping, Mohammed, Nassima Si, Siang, Ng Yong, Sibiude, Jeanne, Siddiqui, Atif, Sigfrid, Louise, Sillaots, Piret, Silva, Catarina, Silva, Rogério, Silva, Maria Joao, Lim Heng, Benedict Sim, Sin, Wai Ching, Singh, Punam, Singh, Budha Charan, Sitompul, Pompini Agustina, Sivam, Karisha, Skogen, Vegard, Smith, Sue, Smood, Benjamin, Smyth, Coilin, Smyth, Michelle, Snacken, Morgane, So, Dominic, Soh, Tze Vee, Solomon, Joshua, Solomon, Tom, Somers, Emily, Sommet, Agnès, Song, Rima, Song, Myung Jin, Song, Tae, Chia, Jack Song, Sotto, Albert, Soum, Edouard, Sousa, Marta, Sousa, Ana Chora, Uva, Maria Sousa, Souza-Dantas, Vicente, Sperry, Alexandra, Spinuzza, Elisabetta, Sriskandan, Shiranee, Stabler, Sarah, Staudinger, Thomas, Stecher, Stephanie-Susanne, Steinsvik, Trude, Stienstra, Ymkje, Stiksrud, Birgitte, Stolz, Eva, Stone, Amy, Streinu-Cercel, Adrian, Streinu-Cercel, Anca, Stuart, Ami, Stuart, David, Su, Richa, Subekti, Decy, Suen, Gabriel, Suen, Jacky Y., Sukumar, Prasanth, Sultana, Asfia, Summers, Charlotte, Supic, Dubravka, Suppiah, Deepashankari, Surovcová, Magdalena, Svistunov, Suwarti; Andrey, Syahrin, Sarah, Syrigos, Konstantinos, Sztajnbok, Jaques, Szuldrzynski, Konstanty, Tabrizi, Shirin, Taccone, Fabio S., Tagherset, Lysa, Taib, Shahdattul Mawarni, Taleb, Sara, Talsma, Jelmer, Tampubolon, Maria Lawrensia, Tan, Kim Keat, Tan, Yan Chyi, Tanaka, Hiroyuki, Tanaka, Taku, Taniguchi, Hayato, Tardivon, Coralie, Tattevin, Pierre, Taufik, M Azhari, Tawfik, Hassan, Tedder, Richard S., Tee, Tze Yuan, Teixeira, João, Tellier, Marie-Capucine, Teoh, Sze Kye, Teotonio, Vanessa, Téoulé, François, Terpstra, Pleun, Terrier, Olivier, Terzi, Nicolas, Tessier-Grenier, Hubert, Tey, Adrian, Mohd Thabit, Alif Adlan, Tham, Zhang Duan, Thangavelu, Suvintheran, Theron, Elmi, Thibault, Vincent, Thiberville, Simon-Djamel, Thill, Benoît, Thirumanickam, Jananee, Thompson, Shaun, Thomson, David, Thomson, Emma C., Thorpe, Mathew, Thanga Thurai, Surain Raaj, Thwaites, Ryan S., Tierney, Paul, Tieroshyn, Vadim, Timashev, Peter S., Timsit, Jean-François, Tissot, Noémie, Toal, Fiona, Yang Toh, Jordan Zhien, Toki, Maria, Tonby, Kristian, Tonnii, Sia Loong, Torre, Marta, Torres, Antoni, Torres-Zevallos, Hernando, Towers, Michael, Trapani, Tony, Tromeur, Cécile, Trontzas, Ioannis, Trouillon, Tiffany, Truong, Jeanne, Tual, Christelle, Tubiana, Sarah, Tuite, Helen, Turgeon, Alexis F., Turmel, Jean-Marie, Turtle, Lance C.W., Tveita, Anders, Twardowski, Pawel, Udy, Andrew, Ullrich, Roman, Uribe, Alberto, Usman, Asad, Uyeki, Timothy M., Vajdovics, Cristinava, Val-Flores, Luís, Valran, Amélie, Van de Velde, Stijn, van den Berge, Marcel, van der Palen, Job, van der Valk, Paul, Van Der Vekens, Nicky, Van der Voort, Peter, Van Der Werf, Sylvie, van Gulik, Laura, Van Hattem, Jarne, van Netten, Carolien, van Veen, Ilonka, Vanel, Noémie, Vanoverschelde, Henk, Varghese, Pooja, Varrone, Michael, Vasudayan, Shoban Raj, Vauchy, Charline, Veeran, Shaminee, Veislinger, Aurélie, Vencken, Sebastian, Ventura, Sara, Verbon, Annelies, Vidal, José Ernesto, Vieira, César, Villanueva, Joy Ann, Villoldo, Andrea, Visseaux, Benoit, Vitiello, Chiara, Vonkeman, Harald, Vuotto, Fanny, Wahab, Noor Hidayu, Wahab, Suhaila Abdul, Wahid, Nadirah Abdul, Wainstein, Marina, Walsh, Laura, Wang, Chih-Hsien, Webb, Steve, Wei, Jia, Wen, Tan Pei, Wesselius, Sanne, Wham, Murray, Whelan, Bryan, White, Nicole, Wicky, Paul Henri, Wiedemann, Aurélie, Wijaya, Surya Otto, Wille, Keith, Willems, Sue, Williams, Bailey, Williams, Virginie, Williams, Patricia J., Wils, Evert-Jan, Wittman, Jessica, Wong, Calvin, Wong, Xin Ci, Wong, Yew Sing, Wong, Teck Fung, Xian, Gan Ee, Xian, Lim Saio, Kuan, Pei Xuan, Xynogalas, Ioannis, Binti Mohd Yakop, Siti Rohani, Yamazaki, Masaki, Yarad, Elizabeth, Yazdanpanah, Yazdan, Liang Hing, Nicholas Yee, Yelnik, Cécile, Yeoh, Chian Hui, Yerkovich, Stephanie, Yokoyama, Toshiki, Yonis, Hodane, Yousif, Obada, Zaaqoq, Akram, Zabbe, Marion, Zahid, Masliza, Zahran, Maram, Binti Zaidan, Nor Zaila, Zambon, Maria, Zambrano, Miguel, Zanella, Alberto, Zaynah, Nurul, Zayyad, Hiba, Zoufaly, Alexander, Zucman, David, Spyrison, Nicholas, Ghadimi, Moji, Chávez-Iñiguez, Jonathan S., Rizo-Topete, Lilia, Pole, Jason D., and Johnson, David W.
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49. Thrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry
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Abdukahil, Sheryl Ann, Abdulkadir, Nurul Najmee, Abe, Ryuzo, Abel, Laurent, Abrous, Amal, Absil, Lara, Acker, Andrew, Adam, Elisabeth, Adrião, Diana, Al Ageel, Saleh, Ahmed, Shakeel, Ainscough, Kate, Aisa, Tharwat, Hssain, Ali Ait, Tamlihat, Younes Ait, Akimoto, Takako, Akmal, Ernita, Akwani, Chika, Al Qasim, Eman, Alalqam, Razi, Alberti, Angela, Al-dabbous, Tala, Alegesan, Senthilkumar, Alessi, Marta, Alex, Beatrice, Alexandre, Kévin, Al-Fares, Abdulrahman, Alfoudri, Huda, Ali, Imran, Alidjnou, Kazali Enagnon, Aliudin, Jeffrey, Alkhafajee, Qabas, Allavena, Clotilde, Allou, Nathalie, Alves, João, Alves, Rita, Alves, João Melo, Cabrita, Joana Alves, Amaral, Maria, Amira, Nur, Ampaw, Phoebe, Andini, Roberto, Andréjak, Claire, Angheben, Andrea, Angoulvant, François, Ansart, Séverine, Anthonidass, Sivanesen, Antonelli, Massimo, de Brito, Carlos Alexandre Antunes, Apriyana, Ardiyan, Arabi, Yaseen, Aragao, Irene, Arancibia, Francisco, Araujo, Carolline, Arcadipane, Antonio, Archambault, Patrick, Arenz, Lukas, Arlet, Jean-Benoît, Arnold-Day, Christel, Arora, Lovkesh, Arora, Rakesh, Artaud-Macari, Elise, Aryal, Diptesh, Asensio, Angel, Ashraf, Muhammad, Assie, Jean Baptiste, Asyraf, Amirul, Atif, Minahel, Atique, Anika, Auchabie, Johann, Aumaitre, Hugues, Auvet, Adrien, Azemar, Laurène, Azoulay, Cecile, Bach, Benjamin, Bachelet, Delphine, Badr, Claudine, Baig, Nadia, Baillie, J. 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Jake, Duplaix, Mathilde, Durante-Mangoni, Emanuele, Durham, Lucian, III, Dussol, Bertrand, Duthoit, Juliette, Duval, Xavier, Dyrhol-Riise, Anne Margarita, Ean, Sim Choon, Echeverria-Villalobos, Marco, Egan, Siobhan, Eira, Carla, El Sanharawi, Mohammed, Elapavaluru, Subbarao, Elharrar, Brigitte, Ellerbroek, Jacobien, Eloy, Philippine, Elshazly, Tarek, Enderle, Isabelle, Endo, Tomoyuki, Eng, Chan Chee, Engelmann, Ilka, Enouf, Vincent, Epaulard, Olivier, Escher, Martina, Esperatti, Mariano, Esperou, Hélène, Santo, Catarina Espírito, Esposito-Farese, Marina, Estevão, João, Etienne, Manuel, Ettalhaoui, Nadia, Everding, Anna Greti, Evers, Mirjam, Fabre, Isabelle, Fabre, Marc, Faheem, Amna, Fahy, Arabella, Fairfield, Cameron J., Faria, Pedro, Fateena, Hanan, Fatoni, Arie Zainul, Faure, Karine, Favory, Raphaël, Fayed, Mohamed, Feely, Niamh, Feeney, Laura, Fernandes, Jorge, Fernandes, Marília Andreia, Fernandes, Susana, Ferrand, François-Xavier, Devouge, Eglantine Ferrand, Ferrão, Joana, Ferraz, Mário, Ferreira, Sílvia, Ferreira, Bernardo, Ferreira, Benigno, Ferreira, Isabel, Ferriere, Nicolas, Ficko, Céline, Figueiredo-Mello, Claudia, Fiorda, Juan, Flament, Thomas, Flateau, Clara, Fletcher, Tom, Florence, Aline-Marie, Florio, Letizia Lucia, Flynn, Deirdre, Foley, Claire, Foley, Jean, Fonseca, Tatiana, Forsyth, Simon, Foster, Denise, Foti, Giuseppe, Fourn, Erwan, Fowler, Robert A., Fraher, Marianne, Franch-Llasat, Diego, Fraser, John F., Fraser, Christophe, Freire, Marcela Vieira, Ribeiro, Ana Freitas, Fritz, Ricardo, Fry, Stéphanie, Fuentes, Nora, Fukuda, Masahiro, Gaborieau, Valérie, Gaci, Rostane, Gagliardi, Massimo, Gagnard, Jean-Charles, Gagneux-Brunon, Amandine, Gaião, Sérgio, Skeie, Linda Gail, Gallagher, Phil, Gamble, Carrol, Gani, Yasmin, Garan, Arthur, Garcia, Rebekha, Barrio, Noelia García, Garcia-Gallo, Esteban, Garot, Denis, Garrait, Valérie, Gault, Nathalie, Gavin, Aisling, Gavrylov, Anatoliy, Gaymard, Alexandre, Gebauer, Johannes, Geraud, Eva, Morlaes, Louis Gerbaud, Germano, Nuno, Ghosn, Jade, Giani, Marco, Gibson, Jess, Gigante, Tristan, Gilg, Morgane, Gilroy, Elaine, Giordano, Guillermo, Girvan, Michelle, Gissot, Valérie, Glikman, Daniel, Gnall, Eric, Goehringer, François, Goepel, Siri, Goffard, Jean-Christophe, Goh, Jin Yi, Golob, Jonathan, Gómez-Junyent, Joan, Gominet, Marie, Gonzalez, Alicia, Gordon, Patricia, Gorenne, Isabelle, Gormley, Conor, Goubert, Laure, Goujard, Cécile, Goulenok, Tiphaine, Grable, Margarite, Graf, Jeronimo, Grandin, Edward Wilson, Granier, Pascal, Grasselli, Giacomo, Green, Christopher A., Greene, Courtney, Greenhalf, William, Greffe, Segolène, Grieco, Domenico Luca, Griffee, Matthew, Griffiths, Fiona, Grigoras, Ioana, Groenendijk, Albert, Gruner, Heidi, Gu, Yusing, Guedj, Jérémie, Guego, Martin, Guellec, Dewi, Guerreiro, Daniela, Guery, Romain, Guillaumot, Anne, Guilleminault, Laurent, de Castro, Maisa Guimarães, Guimard, Thomas, Haalboom, Marieke, Haber, Daniel, Habraken, Hannah, Hachemi, Ali, Hadri, Nadir, Hakak, Sheeba, Hall, Adam, Hall, Matthew, Halpin, Sophie, Hamer, Ansley, Hamidfar, Rebecca, Hammond, Terese, Hammond, Naomi, Han, Lim Yuen, Haniffa, Rashan, Hao, Kok Wei, Hardwick, Hayley, Harrison, Ewen M., Harrison, Janet, Ekow Harrison, Samuel Bernard, Hartman, Alan, Hashmi, Junaid, Hayes, Ailbhe, Hays, Leanne, Heerman, Jan, Heggelund, Lars, Hendry, Ross, Hennessy, Martina, Henriquez-Trujillo, Aquiles, Hentzien, Maxime, Hernandez, Diana, Hernandez-Montfort, Jaime, Hershey, Andrew, Hesstvedt, Liv, Higgins, Eibhlin, Higgins, Dawn, Higgins, Rupert, Hinchion, Rita, Hinton, Samuel, Hiraiwa, Hiroaki, Hitoto, Hikombo, Ho, Antonia, Ho, Yi Bin, Hoctin, Alexandre, Hoffmann, Isabelle, Hoh, Wei Han, Hoiting, Oscar, Holt, Rebecca, Holter, Jan Cato, Horby, Peter, Horcajada, Juan Pablo, Hoshino, Koji, Houas, Ikram, Hough, Catherine L., Houltham, Stuart, Ming-Yang Hsu, Jimmy, Hulot, Jean-Sébastien, Hurd, Abby, Ijaz, Samreen, Ikram, M. Arfan, Illes, Hajnal-Gabriela, Imbert, Patrick, Inácio, Hugo, Infante Dominguez, Carmen, Ing, Yun Sii, Iosifidis, Elias, Ippolito, Mariachiara, Isgett, Sarah, Isidoro, Tiago, Ismail, Nadiah, Isnard, Margaux, Itai, Junji, Ivulich, Daniel, Jaafar, Danielle, Jaafoura, Salma, Jabot, Julien, Jackson, Clare, Janes, Victoria, Jaquet, Pierre, Jassat, Waasila, Jaud-Fischer, Coline, Jaureguiberry, Stéphane, Jaworsky, Denise, Jego, Florence, Jelani, Anilawati Mat, Jenum, Synne, Jimbo-Sotomayor, Ruth, Joe, Ong Yiaw, Jorge García, Ruth N., Joseph, Cédric, Joseph, Mark, Jourdain, Mercé, Jouvet, Philippe, Jung, Anna, Jung, Hanna, Juzar, Dafsah, Kafif, Ouifiya, Kaguelidou, Florentia, Kaisbain, Neerusha, Kaleesvran, Thavamany, Kali, Sabina, Kalomoiri, Smaragdi, Ayadi Kamaluddin, Muhammad Aisar, Che Kamaruddin, Zul Amali, Kamarudin, Nadiah, Kandamby, Darshana Hewa, Kandel, Chris, Kang, Kong Yeow, Karpayah, Pratap, Kartsonaki, Christiana, Kasugai, Daisuke, Kataria, Anant, Katz, Kevin, Kaur, Aasmine, Kay, Christy, Kayyali, Lamees, Keane, Hannah, Keating, Seán, Kelly, Claire, Kelly, Yvelynne, Kelly, Andrea, Kelly, Niamh, Kelly, Aoife, Kelly, Sadie, Kelsey, Maeve, Kennedy, Ryan, Kennon, Kalynn, Kernan, Maeve, Kerroumi, Younes, Keshav, Sharma, Khalid, Imrana, Khalil, Antoine, Khan, Coralie, Khan, Irfan, Kho, Michelle E., Khoo, Saye, Khoo, Ryan, Khoo, Denisa, Kiat, Khor How, Kida, Yuri, Kiiza, Peter, Granerud, Beathe Kiland, Kildal, Anders Benjamin, Kimmoun, Antoine, Kindgen-Milles, Detlef, King, Alexander, Kitamura, Nobuya, Klenerman, Paul, Klont, Rob, Bekken, Gry Kloumann, Knight, Stephen R., Vasconcelos, Malte Kohns, Komatsu, Mamoru, Kosgei, Caroline, Kpangon, Arsène, Krawczyk, Karolina, Krishnan, Sudhir, Krishnan, Vinothini, Kruglova, Oksana, Kumar, Deepali, Kumar, Ganesh, Vecham, Pavan Kumar, Kuriakose, Dinesh, Kurtzman, Ethan, Kutsogiannis, Demetrios, Kutsyna, Galyna, Kyriakoulis, Konstantinos, Lachatre, Marie, Lacoste, Marie, Laffey, John G., Lafhej, Nadhem, Lagrange, Marie, Laine, Fabrice, Lairez, Olivier, Lalueza, Antonio, Lambert, Marc, Lamontagne, François, Langelot-Richard, Marie, Langlois, Vincent, Lantang, Eka Yudha, Lanza, Marina, Laouénan, Cédric, Laribi, Samira, Lariviere, Delphine, Lasry, Stéphane, Launay, Odile, Laureillard, Didier, Lavie-Badie, Yoan, Law, Andy, Lawrence, Teresa, Lawrence, Cassie, Le, Minh, Le Bihan, Clément, Le Bris, Cyril, Le Falher, Georges, Le Fevre, Lucie, Le Hingrat, Quentin, Le Maréchal, Marion, Mestre, Soizic Le, Le Moal, Gwenaël, Le Moing, Vincent, Le Nagard, Hervé, LeTurnier, Paul, Leal, Ema, Santos, Marta Leal, Lee, Todd C., Lee, Su Hwan, Lee, James, Lee, Jennifer, Lee, Heng Gee, Lee, Biing Horng, Lee, Yi Lin, Leeming, Gary, Lefebvre, Bénédicte, Lefebvre, Laurent, Lefèvre, Benjamin, LeGac, Sylvie, Lelievre, Jean-Daniel, Lellouche, François, Lemaignen, Adrien, Lemee, Véronique, Lemeur, Anthony, Lemmink, Gretchen, Lene, Ha Sha, Lennon, Jenny, León, Rafael, Leone, Marc, Leone, Michela, Lepiller, Quentin, Lescure, François-Xavier, Lesens, Olivier, Lesouhaitier, Mathieu, Lester-Grant, Amy, Letrou, Sophie, Levy, Bruno, Levy, Yves, Levy-Marchal, Claire, Lewandowska, Katarzyna, L'Her, Erwan, Bassi, Gianluigi Li, Liegeon, Geoffrey, Lim, Wei Shen, Lim, Kah Chuan, Lima, Chantre, Lina, Bruno, Lina, Lim, Lind, Andreas, Lingas, Guillaume, Lion-Daolio, Sylvie, Lissauer, Samantha, Liu, Keibun, Livrozet, Marine, Lizotte, Patricia, Lolong, Navy, Loon, Leong Chee, Lopes, Diogo, Lopez-Colon, Dalia, Loschner, Anthony L., Loubet, Paul, Loufti, Bouchra, Louis, Guillame, Lourenco, Silvia, Lee Low, Lee, Lowik, Marije, Loy, Jia Shyi, Lucet, Jean-Christophe, Bermejo, Carlos Lumbreras, Luna, Carlos M., Lungu, Olguta, Luong, Liem, Luque, Nestor, Luton, Dominique, Lwin, Nilar, Lyons, Ruth, Maasikas, Olavi, Mabiala, Oryane, Machado, Moïse, Machado, Sara, Macheda, Gabriel, Madiha, Hashmi, de la Calle, Guillermo Maestro, Mahieu, Rafael, Mahy, Sophie, Maia, Ana Raquel, Maier, Lars S., Maillet, Mylène, Maitre, Thomas, Malfertheiner, Maximilian, Malik, Nadia, Mallon, Paddy, Maltez, Fernando, Malvy, Denis, Manda, Victoria, Mandelbrot, Laurent, Manetta, Frank, Mankikian, Julie, Manning, Edmund, Manuel, Aldric, Sant`Ana Malaque, Ceila Maria, Marino, Flávio, Markowicz, Samuel, Marques, Ana, Marquis, Catherine, Marsh, Brian, Marsh, Laura, Marshal, Megan, Marshall, John, Martelli, Celina Turchi, Martin, Emily, Martin-Blondel, Guillaume, Martinez, F. 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Giovanna, Panda, Prasan Kumar, Pang, Lai Hui, Panigada, Mauro, Pansu, Nathalie, Papadopoulos, Aurélie, Parke, Rachael, Pasquier, Jérémie, Pastene, Bruno, Patauner, Fabian, Pathmanathan, Mohan Dass, Patrão, Luís, Patricio, Patricia, Patrier, Juliette, Patterson, Lisa, Paul, Christelle, Paul, Mical, Paulos, Jorge, Paxton, William A., Payen, Jean-François, Peake, Sandra L., Peariasamy, Kalaiarasu, Jiménez, Miguel Pedrera, Peek, Giles J., Peelman, Florent, Peiffer-Smadja, Nathan, Peigne, Vincent, Pejkovska, Mare, Pelosi, Paolo, Peltan, Ithan D., Pereira, Rui, Perez, Daniel, Periel, Luis, Perpoint, Thomas, Pesenti, Antonio, Pestre, Vincent, Petrou, Lenka, Petrovic, Michele, Petrov-Sanchez, Ventzislava, Pettersen, Frank Olav, Peytavin, Gilles, Pharand, Scott, Picard, Walter, Picone, Olivier, de Piero, Maria, Pierobon, Carola, Piersma, Djura, Pimentel, Carlos, Pinto, Raquel, Piquard, Valentine, Pires, Catarina, Pironneau, Isabelle, Piroth, Lionel, Piubelli, Chiara, Pius, Riinu, Plantier, Laurent, Png, Hon Shen, Poissy, Julien, Pokeerbux, Ryadh, Poli, Sergio, Pollakis, Georgios, Ponscarme, Diane, Porto, Diego Bastos, Post, Andra-Maris, Postma, Douwe F., Povoa, Pedro, Póvoas, Diana, Powis, Jeff, Prapa, Sofia, Preau, Sébastien, Prebensen, Christian, Preiser, Jean-Charles, Prinssen, Anton, Pritchard, Mark G., Proença, Lucia, Pudota, Sravya, Puéchal, Oriane, Semedi, Bambang Pujo, Purcell, Gregory, Quesada, Luisa, González, Víctor Quirós, Quist-Paulsen, Else, Quraishi, Mohammed, Qutishat, Fadi, Rabaud, Christian, Rafael, Aldo, Rafiq, Marie, Rahman, Rozanah Abd, Haji Ab Rahman, Ahmad Kashfi, Rainieri, Fernando, Rajahram, Giri Shan, Ramakrishnan, Nagarajan, Ramalho, José, Ramli, Ahmad Afiq, Rammaert, Blandine, Ramos, Grazielle Viana, Ranjan, Ritika, Rapp, Christophe, Rasmin, Menaldi, Rätsep, Indrek, Ravi, Tharmini, Real, Andre, Rebaudet, Stanislas, Redl, Sarah, Reeve, Brenda, Reid, Liadain, Reikvam, Dag Henrik, Reis, Renato, Rello, Jordi, Remppis, Jonathan, Remy, Martine, Ren, Hongru, Renk, Hanna, Resseguier, Anne-Sophie, Revest, Matthieu, Rewa, Oleksa, Reyes, Tiago, Reyes, Luis Felipe, Ribeiro, Maria Ines, Richardson, David, Richardson, Denise, Richier, Laurent, Atikah Ahmad Ridzuan, Siti Nurul, Rios, Ana L., Rishu, Asgar, Rispal, Patrick, Risso, Karine, Rizer, Nicholas, Robba, Chiara, Roberto, André, Roberts, Stephanie, Robertson, David L., Robineau, Olivier, Roche-Campo, Ferran, Rodari, Paola, Rodeia, Simão, Roessler, Bernhard, Roger, Pierre-Marie, Roger, Claire, Roilides, Emmanuel, Rojek, Amanda, Romaru, Juliette, Roncon-Albuquerque, Roberto, Jr., Roriz, Mélanie, Rosa-Calatrava, Manuel, Rose, Michael, Rosenberger, Dorothea, Rossanese, Andrea, Rossetti, Matteo, Rossignol, Bénédicte, Rossignol, Patrick, Rousset, Stella, Roy, Carine, Roze, Benoît, Russell, Clark D., Ryan, Maria, Ryan, Maeve, Ryckaert, Steffi, Holten, Aleksander Rygh, Saba, Isabela, Sadat, Musharaf, Sahraei, Valla, Saint-Gilles, Maximilien, Sakiyalak, Pranya, Salazar, Leonardo, Sales, 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Shi, Haixia, Shime, Nobuaki, Shimizu, Keiki, Shrapnel, Sally, Shum, Hoi Ping, Mohammed, Nassima Si, Siang, Ng Yong, Sibiude, Jeanne, Siddiqui, Atif, Sigfrid, Louise, Sillaots, Piret, Silva, Catarina, Silva, Rogério, Silva, Maria Joao, Lim Heng, Benedict Sim, Sin, Wai Ching, Singh, Punam, Singh, Budha Charan, Sitompul, Pompini Agustina, Sivam, Karisha, Skogen, Vegard, Smith, Sue, Smood, Benjamin, Smyth, Coilin, Smyth, Michelle, Snacken, Morgane, So, Dominic, Soh, Tze Vee, Solomon, Joshua, Solomon, Tom, Somers, Emily, Sommet, Agnès, Song, Rima, Song, Myung Jin, Song, Tae, Chia, Jack Song, Sonntagbauer, Michael, Soom, Azlan Mat, Sotto, Albert, Soum, Edouard, Sousa, Marta, Sousa, Ana Chora, Uva, Maria Sousa, Souza-Dantas, Vicente, Sperry, Alexandra, Spinuzza, Elisabetta, Sriskandan, Shiranee, Stabler, Sarah, Staudinger, Thomas, Stecher, Stephanie-Susanne, Steinsvik, Trude, Stienstra, Ymkje, Stiksrud, Birgitte, Stolz, Eva, Stone, Amy, Streinu-Cercel, Adrian, Streinu-Cercel, Anca, Stuart, 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- Published
- 2023
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50. A minimal common outcome measure set for COVID-19 clinical research
- Author
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infection, WHO Working Group on the Clinical Characterisation and Management of COVID-19, Marshall, John C, Murthy, Srinivas, Diaz, Janet, Adhikari, NK, Angus, Derek C, Arabi, Yaseen M, Baillie, Kenneth, Bauer, Michael, Berry, Scott, Blackwood, Bronagh, Bonten, Marc, Bozza, Fernando, Brunkhorst, Frank, Cheng, Allen, Clarke, Mike, Dat, Vu Quoc, de Jong, Menno, Denholm, Justin, Derde, Lennie, Dunning, Jake, Feng, Xiaobin, Fletcher, Tom, Foster, Nadine, Fowler, Rob, Gobat, Nina, Gomersall, Charles, Gordon, Anthony, Glueck, Thomas, Harhay, Michael, Hodgson, Carol, Horby, Peter, Kim, YaeJean, Kojan, Richard, Kumar, Bharath, Laffey, John, Malvey, Denis, Martin-Loeches, Ignacio, McArthur, Colin, McAuley, Danny, McBride, Stephen, McGuinness, Shay, Merson, Laura, Morpeth, Susan, Needham, Dale, Netea, Mihai, Oh, Myoung-Don, Phyu, Sabai, Piva, Simone, Qiu, Ruijin, Salisu-Kabara, Halima, Shi, Lei, Shimizu, Naoki, Sinclair, Jorge, Tong, Steven, Turgeon, Alexis, Uyeki, Tim, van de Veerdonk, Frank, Webb, Steve, Williamson, Paula, Wolf, Timo, and Zhang, Junhua
- Subjects
Biomedical and Clinical Sciences ,Clinical Sciences ,Rare Diseases ,Infectious Diseases ,Infection ,Good Health and Well Being ,Betacoronavirus ,COVID-19 ,Clinical Trials as Topic ,Coronavirus Infections ,Humans ,Outcome Assessment ,Health Care ,Pandemics ,Patient Outcome Assessment ,Pneumonia ,Viral ,SARS-CoV-2 ,Survival Analysis ,Treatment Outcome ,Viral Load ,WHO Working Group on the Clinical Characterisation and Management of COVID-19 infection ,Medical Microbiology ,Public Health and Health Services ,Microbiology ,Clinical sciences ,Medical microbiology ,Epidemiology - Abstract
Clinical research is necessary for an effective response to an emerging infectious disease outbreak. However, research efforts are often hastily organised and done using various research tools, with the result that pooling data across studies is challenging. In response to the needs of the rapidly evolving COVID-19 outbreak, the Clinical Characterisation and Management Working Group of the WHO Research and Development Blueprint programme, the International Forum for Acute Care Trialists, and the International Severe Acute Respiratory and Emerging Infections Consortium have developed a minimum set of common outcome measures for studies of COVID-19. This set includes three elements: a measure of viral burden (quantitative PCR or cycle threshold), a measure of patient survival (mortality at hospital discharge or at 60 days), and a measure of patient progression through the health-care system by use of the WHO Clinical Progression Scale, which reflects patient trajectory and resource use over the course of clinical illness. We urge investigators to include these key data elements in ongoing and future studies to expedite the pooling of data during this immediate threat, and to hone a tool for future needs.
- Published
- 2020
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