334 results on '"Martin, Rainer E."'
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2. Simple User-Friendly Reaction Format
3. RG7774 (Vicasinabin), an orally bioavailable cannabinoid receptor 2 (CB2R) agonist, decreases retinal vascular permeability, leukocyte adhesion, and ocular inflammation in animal models.
4. Geometric deep learning-guided Suzuki reaction conditions assessment for applications in medicinal chemistry.
5. sp3‐Rich Heterocycle Synthesis on DNA: Application to DNA‐Encoded Library Production
6. Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning
7. Development and Demonstration of a High-Volume Manufacturing Process for a Key Intermediate of Dalcetrapib: Investigations on the Alkylation of Carboxylic Acids, Esters, and Nitriles
8. Simple User-Friendly Reaction Format
9. A carbohydrate-derived trifunctional scaffold for DNA-encoded libraries
10. sp3‐Rich Heterocycle Synthesis on DNA: Application to DNA‐Encoded Library Production.
11. Graph transformer neural network for chemical reactivity prediction
12. Going with the flow
13. Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning
14. Investigations into mRNA Lipid Nanoparticles Shelf-Life Stability under Nonfrozen Conditions.
15. Diligent Design Enables Antibody-ASO Conjugates with Optimal Pharmacokinetic Properties.
16. Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning
17. Rapid 18F‐ and 19F‐Difluoromethylation through Desulfurative Fluorination of Transient N‐, O‐, and C‐Linked Dithioles
18. Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning
19. Late-stage Functionalization and its Impact on Modern Drug Discovery
20. CHEMICAL SYNTHESIS: Going with theflow
21. Rapid 18F‐ and 19F‐Difluoromethylation through Desulfurative Fluorination of Transient N‐, O‐, and C‐Linked Dithioles.
22. Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R-dependent manner
23. Direct heterobenzylic fluorination, difluorination and trifluoromethylthiolation with dibenzenesulfonamide derivatives† †Electronic supplementary information (ESI) available: Experimental procedures, purification and characterization data for all new compounds. See DOI: 10.1039/c8sc01221k
24. Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R-dependent manner
25. Quaternary Ammonium Trifluoromethoxide Salts as Stable Sources of Nucleophilic OCF3
26. Electronic characteristics of arylated tetraethynylethenes: a cooperative computational and electrochemical investigation
27. Ligand identification for G-protein-coupled receptors: a lead generation perspective
28. Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice
29. Paracrine crosstalk between intestinal L- and D-cells controls secretion of glucagon-like peptide-1 in mice
30. A Convenient Synthesis of Difluoroalkyl Ethers from Thionoesters Using Silver(I) Fluoride
31. Modulation of Pharmacologically Relevant Properties of Piperidine Derivatives by Functional Groups in an Equatorial or Axial β‐Position to the Amino Group
32. Electrostatic Effects Accelerate Decatungstate-Catalyzed C–H Fluorination Using [18F]- and [19F]NFSI in Small Molecules and Peptide Mimics
33. 18F-Fluorination of Unactivated C-H Bonds in Branched Aliphatic Amino Acids: Direct Synthesis of Oncological PET Imaging Agents
34. Synthesis of conjugated polymers for application in light-emitting diodes (PLEDs)
35. Modulation of Pharmacologically Relevant Properties of Piperidine Derivatives by Functional Groups in an Equatorial or Axial β‐Position to the Amino Group.
36. A carbohydrate-derived trifunctional scaffold for medicinal chemistry library synthesis
37. Site-Selective, Late-Stage C−H 18 F-Fluorination on Unprotected Peptides for Positron Emission Tomography Imaging
38. 2H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design
39. Synthesis of acyl fluorides via photocatalytic fluorination of aldehydic C–H bonds
40. Synthesis of light-emitting conjugated polymers for applications in electroluminescent devices
41. Scale-Up of Flow-Assisted Synthesis of C2-Symmetric Chiral PyBox Ligands
42. Prospective Evaluation of Free Energy Calculations for the Prioritization of Cathepsin L Inhibitors
43. 18F-Fluorination of Unactivated C–H Bonds in Branched Aliphatic Amino Acids: Direct Synthesis of Oncological Positron Emission Tomography Imaging Agents
44. Intramolecular Inverse Electron-Demand [4 + 2] Cycloadditions of Ynamides with Pyrimidines: Scope and Density Functional Theory Insights
45. 18F-branched chain amino acids: structure-activity relationships and PET imaging potential.
46. Electrostatic Effects Accelerate Decatungstate-Catalyzed C–H Fluorination Using [18F]- and [19F]NFSI in Small Molecules and Peptide Mimics.
47. Flow synthesis of annulated 5-aryl-substituted pyridines by tandem intramolecular inverse-electron-demand hetero-/retro-Diels–Alder reaction
48. Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonists
49. A Convenient Late-Stage Fluorination of Pyridylic C−H Bonds with N -Fluorobenzenesulfonimide
50. ChemInform Abstract: Inverse Electron‐Demand [4 + 2]‐Cycloadditions of Ynamides: Access to Novel Pyridine Scaffolds.
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