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Exposure to toxic environmental chemicals during pregnancy and breastfeeding is ubiquitous and is a threat to healthy human reproduction. There are tens of thousands of chemicals in global commerce, and even small exposures to toxic chemicals during pregnancy can trigger adverse health consequences. Exposure to toxic environmental chemicals and related health outcomes are inequitably distributed within and between countries; universally, the consequences of exposure are disproportionately borne by people with low incomes. Discrimination, other social factors, economic factors, and occupation impact risk of exposure and harm. Documented links between prenatal exposure to environmental chemicals and adverse health outcomes span the life course and include impacts on fertility and pregnancy, neurodevelopment, and cancer. The global health and economic burden related to toxic environmental chemicals is in excess of millions of deaths and billions of dollars every year. On the basis of accumulating robust evidence of exposures and adverse health impacts related to toxic environmental chemicals, the International Federation of Gynecology and Obstetrics (FIGO) joins other leading reproductive health professional societies in calling for timely action to prevent harm. FIGO recommends that reproductive and other health professionals advocate for policies to prevent exposure to toxic environmental chemicals, work to ensure a healthy food system for all, make environmental health part of health care, and champion environmental justice.

When planning and conducting a Mission Engineering (ME) study, it is important to have a complete, correct, and coherent model of the mission architecture. The Unified Architecture Framework (UAF) has been found to be effective for this purpose. The OUSD (R&E) Mission Integration office is exploring how to use UAF for their ME architectures. This paper will explore some of the required modeling features and constructs that will enable this to occur. The paper "Implementing Mission Engineering with UAF" was presented at a previous conference and this paper will expand on that presentation and will discuss additional work that has been accomplished since then. This paper will also explore the proposed extensions for UAF to better support ME. We created a prototype model using the Battle of Hoth from Star Wars as a proof of concept for these modeling extensions and used the process and ME concepts defined in the Mission Engineering Guide (MEG). Since then there have been several concepts that were explored such as compatibility with the Model‐Based Acquisition (MBAcq) approach, recent initiatives from the Office of the Assistant Secretary of Defense for Mission Capabilities, Enterprise Systems Engineering (ESE) process and methods, detailed resource engagement, use of different modeling languages (e.g., Systems Modeling Language (SysML), SysML v2 and UAF v2), Effects and Outcomes, variety of measures, additional attributes/stereotypes such as differentiation between enemy/friendly/neutral ‐ Blue Force, Red Force, etc., provenance/confidence of enemy resources, and so forth. This paper will summarize the research and modeling done to date and explore these additional concepts as well as new ideas introduced in the MEG v2. [ABSTRACT FROM AUTHOR]

The purpose of this paper is to explore the concept of 'enterprise' in the context of Systems Engineering (SE). The term 'enterprise' has been used extensively to generally describe large complex entities that have an extensive scope of operations. However, a deeper examination of 'enterprise' significance for SE can provide insights as our challenges continue with increasingly complex, uncertain, ambiguous, and integrated entities struggling to thrive in the future. The paper explores three central topics. First, the concept of enterprise is introduced as a central aspect of the future focus for SE, as recognized in the INCOSE SE Vision 2035. Second, a more detailed examination of the enterprise concept is developed in relationship to SE. The thrust of this examination is to understand the nature and role of 'enterprise' across a broad spectrum of literature and knowledge, ultimately providing a more informed perspective of enterprise for SE. As part of this exploration, a bibliometric analysis of the term 'enterprise' is performed. This exploration extracts key themes (clusters) in the 'enterprise' literature. Third, challenges for further development and inculcation of 'enterprise' within the SE discipline and support for realization of the SE 2035 Vision are suggested. These challenges point out the need to 'think differently' about 'enterprise' within the SE context. 'Enterprise' is proposed as a central, albeit different, perspective for the SE discipline. The paper closes with a first‐generation perspective for 'enterprise' in pursuit of the SE Vision 2035. [ABSTRACT FROM AUTHOR]