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2. Characterization of patients with extensive left atrial myopathy referred for atrial fibrillation ablation: incidence, predictors, and outcomes

Author

González-Ferrero, Teba, Bergonti, Marco, Marcon, Lorenzo, Minguito-Carazo, Carlos, Tilves Bellas, Carlos, Pesquera Lorenzo, Juan Carlos, Martínez-Sande, José Luis, González-Melchor, Laila, García-Seara, Francisco Javier, Fernández-López, Jesús Alberto, González-Juanatey, José Ramón, Heidbuchel, Hein, Sarkozy, Andrea, and Rodríguez-Mañero, Moisés

Published
2024
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3. Spanish catheter ablation registry. 23rd official report of the Heart Rhythm Association of the Spanish Society of Cardiology (2023)

Author

Bazan, Victor, Arana, Eduardo, Rubio-Campal, José Manuel, Calvo, David, Álvarez Acosta, Luis, Hernández Afonso, Julio, Ramos Ardanaz, Pablo, Peñafiel Verdú, Pablo, Cano Calabria, Lucas R., Barrera Cordero, Alberto, Díaz Infante, Ernesto, Cózar León, Rocío, Lozano Granero, Vanesa Cristina, Martínez Sande, José Luis, Moya Mitjans, Àngel, Rodríguez Entem, Felipe, Salgado Aranda, Ricardo, Gil Ortega, Ignacio, Cabanas Grandío, Pilar, Alcalde Rodriguez, Óscar, García Fernández, Francisco Javier, Sarquella-Brugada, Georgia, Castro Urda, Víctor, Fidalgo Andrés, María Luisa, Durán Guerrero, J. Manuel, Mazuelos Bellido, Francisco, Rubio Caballero, Jose Amador, Pérez Roselló, Víctor, Cabrera Ramos, Mercedes, Rubio Campal, José Manuel, Porta Sánchez, Andreu, Hidalgo Olivares, Víctor M., Rubín López, José Manuel, Jiménez López, Jesús, Grande Morales, Carlos Eugenio, Fernández Gómez, Juan Manuel, Jiménez Candil, Javier, Moreno Garrido, Rafael, Moraleda Salas, María Teresa, Rodríguez Muñoz, Daniel, Vázquez Esmorís, Iván, Ibáñez Criado, José Luis, Ibáñez Criado, Alicia, Arcocha Torres, María Fe, Bastos Amador, Pablo, Elices Teja, Juliana, Pavón Jiménez, Ricardo, Álvarez López, Miguel, Martín Sánchez, Gabriel, Benezet Mazuecos, Juan, Gómez Pulido, Federico, Arce León, Alvaro, Quesada Dorador, Aurelio, Mendoza Lemes, Haridian, Herreros Guilarte, Benito, Osca Asensi, Joaquín, Datino Romaniega, Tomás, Sarrias, Axel, Ferrer Hita, Julio Jesús, Lozano Herrera, José Miguel, Ángel Arias, Miguel, Rivas Gandara, Nuria, Sánchez Borque, Pepa, García Cuenca, Enrique, Bochard Villanueva, Bruno, Alonso Fernández, Pau, Valverde André, Irene, Sandín Fuentes, María de Gracia, Pastor Fuentes, Agustín, Portales Fernández, Javier, Ruiz Hernández, Pablo M., Guasch Casany, Eduard, Pedrote, Alonso, Asso Abadía, Antonio, Guerra Ramos, Jose Maria, Anguera, Ignasi, Cantalapierda, Javier, Sainz Godoy, Íñigo, Domínguez Mafé, Eloy, Rodriguez Font, Enrique, Martí Almor, Julio, Moreno Arribas, José, Merino Llorens, José Luis, Bertomeu González, Vicente, Benito Martín, Eva María, Mosquera Pérez, Ignacio, Peláez González, Antonio, Jiménez Díaz, Francisco Javier, Saurí Ortiz, Assumpció, Luque Lezcano, Antonio Óscar, Segura Villalobos, Federico, Almendral Garrote, Jesús, Salvador Montañés, Óscar, González Ferrer, Juan José, Peinado Peinado, Rafael, Fabregat Andrés, Óscar, Arenal, Ángel, Moreno, Sara, and del Castillo, Álvaro Marco

Published
2024
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4. Impact of initiation of SGLT2 inhibitor treatment on the development of arrhythmias in patients with implantable cardiac devices

Author

Minguito-Carazo, Carlos, Sánchez Muñoz, Enrique, Rodríguez Mañero, Moisés, Martínez-Sande, José Luis, Fidalgo Andrés, María Luisa, García Seara, Javier, González Rebollo, José María, Rodríguez Santamarta, Miguel, González Melchor, Laila, González Ferrero, Teba, Romero Roche, Laura, Fernández López, Jesús Alberto, Tundidor Sanz, Elena, Fernández Vázquez, Felipe, and González-Juanatey, José Ramón

Published
2024
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5. Impacto del inicio del tratamiento con iSGLT2 en el desarrollo de arritmias en pacientes portadores de dispositivos cardiacos implantables

Author

Minguito-Carazo, Carlos, Sánchez Muñoz, Enrique, Rodríguez Mañero, Moisés, Martínez-Sande, José Luis, Fidalgo Andrés, María Luisa, García Seara, Javier, González Rebollo, José María, Rodríguez Santamarta, Miguel, González Melchor, Laila, González Ferrero, Teba, Romero Roche, Laura, Fernández López, Jesús Alberto, Tundidor Sanz, Elena, Fernández Vázquez, Felipe, and González-Juanatey, José Ramón

Published
2024
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6. Spanish catheter ablation registry. 22nd official report of the Heart Rhythm Association of the Spanish Society of Cardiology (2022)

Author

Alcalde-Rodríguez, Óscar, Almendral-Garrote, Jesús, Alonso-Fernández, Pau, Álvarez-López, Miguel, Álvarez-Acosta, Luis, Anguera-Camos, Ignasi, Arce-León, Álvaro, Arenal, Ángel, Palomares, Miguel Ángel Arias, Arocha-Torres, María Fe, Asso-Abadía, Antonio, Barrera-Cordero, Alberto, Bastos-Amador, Pablo, Benezet-Mazuecos, Juan, Benito-Martínez, Eva María, Bochard-Villanueva, Bruno, Cabanas-Grandío, Pilar, Cabrera-Ramos, Mercedes, Cano-Calabria, Lucas R., del Castillo-Arrojo, Silvia, Cerveró, Alba, Datino-Romaniega, Tomás, Díaz-Infante, Ernesto, Domínguez-Mafé, Eloy, Durán-Guerrero, Juan Manuel, Teja, Juliana Elices, Emilce-Trucco, María, Espinosa-Viamonte, Hildemari, Fabregat-Andrés, Óscar, Fernández-Palacios, Gonzalo, Fernández-Lozano, Ignacio, Fernández-Gómez, Juan Manuel, Ferrer-Hita, Julio Jesús, Fidalgo-Andrés, María Luisa, García-Cuenca, Enrique, García-Rodríguez, Daniel, García-Fernández, Francisco Javier, Gil-Ortega, Ignacio, Gómez-Pulido, Federico, González-Ferrer, Juan José, Grande-Morales, Carlos Eugenio, Guasch-Casany, Eduard, Guerra-Ramos, José María, Herreros-Guilarte, Benito, Hidalgo-Olivares, Víctor Manuel, Ibáñez-Criado, Alicia, Ibáñez-Criado, José Luis, Jiménez-Díaz, Francisco Javier, Jiménez-López, Jesús, Jiménez-Candil, Javier, Lozano-Granero, Vanesa Cristina, Luque-Lezcano, Antonio Óscar, Martí-Almor, Julio, Martín-Sánchez, Gabriel, Martínez-Sande, José Luis, Martínez-Brotons, Ángel Miguel, Mazuelos-Bellido, Francisco, Mendoza-Lemes, Haridian, Menéndez-Ramírez, Diego, Merino-Llorens, José Luis, Moreno-Arribas, José, Moriña-Vázquez, Pablo, Mosquera-Pérez, Ignacio, Moya-Mitjans, Ángel, Osca-Asensi, Joaquín, Pastor-Fuentes, Agustín, Pavón-Jiménez, Ricardo, Pedrote-Martínez, Alonso, Peinado-Peinado, Rafael, Peláez-González, Antonio, Peñafiel-Verdú, Pablo, Pérez-Roselló, Víctor, Porta-Sánchez, Andreu, Portales-Fernández, Javier, Quesada-Dorador, Aurelio, Ramos-Ardanaz, Pablo, Rivas-Gándara, Nuria, Rodríguez-Entem, Felipe José, Rodríguez-Font, Enrique, Rodríguez-Muñoz, Daniel, Romero-Garrido, Rafael, Rubín-López, José Manuel, Rubio-Caballero, José Amador, Rubio-Campal, José Manuel, Ruíz-Duthil, Ana Delia, Ruíz-Hernández, Pablo M., Sainz-Godoy, Íñigo, Salgado-Aranda, Ricardo, Salvador-Montañés, Óscar, Sánchez-Borque, Pepa, Sandín-Fuentes, María de Gracia, Sarquella-Brugada, Georgia, Sarrias-Mercè, Axel, Saurí-Ortiz, Assumpció, Segura-Villalobos, Federico, Valverde-André, Irene, Vázquez-Esmorís, Iván, Cano, Óscar, Bazán, Víctor, and Arana, Eduardo

Published
2023
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7. Registro español de ablación con catéter. XXII informe oficial de la Asociación del Ritmo Cardiaco de la Sociedad Española de Cardiología (2022)

Author

Alcalde-Rodríguez, Óscar, Almendral-Garrote, Jesús, Alonso-Fernández, Pau, Álvarez-López, Miguel, Álvarez-Acosta, Luis, Anguera-Camos, Ignasi, Arce-León, Álvaro, Arenal, Ángel, Palomares, Miguel Ángel Arias, Arocha-Torres, María Fe, Asso-Abadía, Antonio, Barrera-Cordero, Alberto, Bastos-Amador, Pablo, Benezet-Mazuecos, Juan, Benito-Martínez, Eva María, Bochard-Villanueva, Bruno, Cabanas-Grandío, Pilar, Cabrera-Ramos, Mercedes, Cano-Calabria, Lucas R., del Castillo-Arrojo, Silvia, Cerveró, Alba, Datino-Romaniega, Tomás, Díaz-Infante, Ernesto, Domínguez-Mafé, Eloy, Durán-Guerrero, Juan Manuel, Teja, Juliana Elices, Emilce-Trucco, María, Espinosa-Viamonte, Hildemari, Fabregat-Andrés, Óscar, Fernández-Palacios, Gonzalo, Fernández-Lozano, Ignacio, Fernández-Gómez, Juan Manuel, Ferrer-Hita, Julio Jesús, Fidalgo-Andrés, María Luisa, García-Cuenca, Enrique, García-Rodríguez, Daniel, García-Fernández, Francisco Javier, Gil-Ortega, Ignacio, Gómez-Pulido, Federico, González-Ferrer, Juan José, Grande-Morales, Carlos Eugenio, Guasch-Casany, Eduard, Guerra-Ramos, José María, Herreros-Guilarte, Benito, Hidalgo-Olivares, Víctor Manuel, Ibáñez-Criado, Alicia, Ibáñez-Criado, José Luis, Jiménez-Díaz, Francisco Javier, Jiménez-López, Jesús, Jiménez-Candil, Javier, Lozano-Granero, Vanesa Cristina, Luque-Lezcano, Antonio Óscar, Martí-Almor, Julio, Martín-Sánchez, Gabriel, Martínez-Sande, José Luis, Martínez-Brotons, Ángel Miguel, Mazuelos-Bellido, Francisco, Mendoza-Lemes, Haridian, Menéndez-Ramírez, Diego, Merino-Llorens, José Luis, Moreno-Arribas, José, Moriña-Vázquez, Pablo, Mosquera-Pérez, Ignacio, Moya-Mitjans, Ángel, Osca-Asensi, Joaquín, Pastor-Fuentes, Agustín, Pavón-Jiménez, Ricardo, Pedrote-Martínez, Alonso, Peinado-Peinado, Rafael, Peláez-González, Antonio, Peñafiel-Verdú, Pablo, Pérez-Roselló, Víctor, Porta-Sánchez, Andreu, Portales-Fernández, Javier, Quesada-Dorador, Aurelio, Ramos-Ardanaz, Pablo, Rivas-Gándara, Nuria, Rodríguez-Entem, Felipe José, Rodríguez-Font, Enrique, Rodríguez-Muñoz, Daniel, Romero-Garrido, Rafael, Rubín-López, José Manuel, Rubio-Caballero, José Amador, Rubio-Campal, José Manuel, Ruíz-Duthil, Ana Delia, Ruíz-Hernández, Pablo M., Sainz-Godoy, Íñigo, Salgado-Aranda, Ricardo, Salvador-Montañés, Óscar, Sánchez-Borque, Pepa, Sandín-Fuentes, María de Gracia, Sarquella-Brugada, Georgia, Sarrias-Mercè, Axel, Saurí-Ortiz, Assumpció, Segura-Villalobos, Federico, Valverde-André, Irene, Vázquez-Esmorís, Iván, Cano, Óscar, Bazán, Víctor, and Arana, Eduardo

Published
2023
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8. Gender-Related Differences in Atrial Substrate in Patients with Atrial Fibrillation

Author

Van Leuven, Olivier, Bergonti, Marco, Spera, Francesco Raffaele, Ferrero, Teba Gonzalez, Nsahlai, Michelle, Bilotta, Giada, Tijskens, Maxime, Boris, Wim, Saenen, Johan, Huybrechts, Wim, Miljoen, Hielko, González-Juanatey, Jose Ramón, Martínez-Sande, Jose Luis, Vandaele, Lien, Wittock, Anouk, Heidbuchel, Hein, Valderrábano, Miguel, Rodríguez-Mañero, Moises, and Sarkozy, Andrea

Published
2023
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9. Leadless pacemaker implant, anticoagulation status, and outcomes: Results from the Micra Transcatheter Pacing System Post-Approval Registry

Author

El-Chami, Mikhael F., Garweg, Christophe, Iacopino, Saverio, Al-Samadi, Faisal, Martinez-Sande, Jose Luis, Tondo, Claudio, Johansen, Jens Brock, Prat, Xavier Viñolas, Piccini, Jonathan P., Cha, Yong Mei, Grubman, Eric, Bordachar, Pierre, Roberts, Paul R., Soejima, Kyoko, Stromberg, Kurt, Fagan, Dedra H., and Clementy, Nicolas

Published
2022
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10. Relaxin-2 plasma levels in atrial fibrillation are linked to inflammation and oxidative stress markers

Author

Aragón-Herrera, Alana, Couselo-Seijas, Marinela, Feijóo-Bandín, Sandra, Anido-Varela, Laura, Moraña-Fernández, Sandra, Tarazón, Estefanía, Roselló-Lletí, Esther, Portolés, Manuel, Martínez-Sande, José Luis, García-Seara, Javier, Álvarez, Ezequiel, González-Juanatey, José Ramón, Rodríguez-Mañero, Moisés, Eiras, Sonia, and Lago, Francisca

Published
2022
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11. Long-term prognosis of women with Brugada syndrome and electrophysiological study

Author

Rodríguez-Mañero, Moisés, Jordá, Paloma, Hernandez, Jaime, Muñoz, Carmen, Grima, Esther Zorio, García-Fernández, Amaya, Cañadas-Godoy, María Victoria, Jiménez-Ramos, Victor, Oloriz, Teresa, Basterra, Nuria, Calvo, David, Pérez-Álvarez, Luisa, Arias, Miguel A., Expósito, Victor, Alemán, Ailema, Díaz-Infante, Ernesto, Guerra-Ramos, Jose María, Fernández-Armenta, Juan, Arce-Leon, Álvaro, Sanchez-Gómez, Juan M., Sousa, Pedro, García-Bolao, Ignacio, Baluja, Aurora, Campuzano, Oscar, Sarquella-Brugada, Georgia, Martinez-Sande, Jose Luis, González-Juanatey, Jose R., Gimeno, Juan Ramón, Brugada, Josep, and Arbelo, Elena

Published
2021
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14. Rate-dependent conduction block of the crista terminalis in patients with typical atrial flutter: Influence on evaluation of cavotricuspid isthmus conduction block

Author

Arenal, Ángel, Almendral Garrote, Jesús, Alday, Jesús M., Pérez Villacastín Domínguez, Julián, Ormaetxe, José M., Martínez Sande, José Luis, Pérez Castellano, Nicasio, González, Sergio, Ortiz, Mercedes, Delcán Domínguez, Juan Luis, Arenal, Ángel, Almendral Garrote, Jesús, Alday, Jesús M., Pérez Villacastín Domínguez, Julián, Ormaetxe, José M., Martínez Sande, José Luis, Pérez Castellano, Nicasio, González, Sergio, Ortiz, Mercedes, and Delcán Domínguez, Juan Luis

Abstract

Background: The crista terminalis (CT) has been identified as the posterior boundary of typical atrial flutter (AFL) in the lateral wall (LW) of the right atrium (RA). To study conduction properties across the CT, rapid pacing was performed at both sides of the CT after bidirectional conduction block was achieved in the cavotricuspid isthmus by radiofrequency catheter ablation. Methods and results: In 22 patients (aged 61+/-7 years) with AFL (cycle length, 234+/-23 ms), CT was identified during AFL by double electrograms recorded between the LW and posterior wall (PW). After the ablation procedure, decremental pacing trains were delivered from 600 ms to 2-to-1 local capture at the LW and PW or coronary sinus ostium (CSO). At least 5 bipolar electrograms were recorded along the CT from the high to the low atrium next to the inferior vena cava. No double electrograms were recorded during sinus rhythm in that area. Complete transversal conduction block all along the CT (detected by the appearance of double electrograms at all recording sites and craniocaudal activation sequence on the side opposite to the pacing site) was observed in all patients during pacing from the PW or CSO (cycle length, 334+/-136 ms), but it was fixed in only 4 patients. During pacing from the LW, complete block appeared at a shorter pacing cycle length (281+/-125 ms; P<0.01) and was fixed in 2 patients. In 3 patients, complete block was not achieved. Conclusions: These data suggest the presence of rate-dependent transversal conduction block at the crista terminalis in patients with typical AFL. Block is usually observed at longer pacing cycle lengths with PW pacing than with LW pacing. This difference may be a critical determinant of the counterclockwise rotation of typical AFL, Depto. de Medicina, Fac. de Medicina, TRUE, pub

Published
2024

16. Spanish Catheter Ablation Registry. 18th Official Report of the Spanish Society of Cardiology Working Group on Electrophysiology and Arrhythmias (2018)

Author

Almendral-Garrote, Jesús, Alonso-Fernández, Pau, Alonso-Martín, Concepción, Alvarenga-Recalde, Nelson María, Álvarez-Acosta, Luis, Álvarez-López, Miguel, Anguera-Camos, Ignasi, Arana-Rueda, Eduardo, Arcocha-Torres, María Fe, Arias-Palomares, Miguel Ángel, Asso-Abadía, Antonio, Ballesteros-Derbenti, Gabriel Alejandro, Barrera-Cordero, Alberto, Benezet-Mazuecos, Juan, Bodegas-Cañas, Andrés I., Brugada-Terradellas, Josep, Cabadés-Rumbeu, Claudia, Cabanas-Grandío, María del Pilar, Cabrera-Gómez, Sandra, Cano-Calabria, Lucas R., del Castillo-Arrojo, Silvia, Castro-Urda, Víctor, Cózar-León, Rocío, Díaz-Infante, Ernesto, Durán-Guerrero, Juan Manuel, Elices-Teja, Juliana, Expósito-Pineda, María del Carmen, Fernández-Gómez, Juan Manuel, Ferrer-Hita, Julio Jesús, Fidalgo-Andrés, María Luisa, Fontenla-Cerezuela, Adolfo, García-Alberola, Arcadio, García-Bolao, J. Ignacio, García-Cuenca, Enrique, García-Fernández, Francisco Javier, Gil-Ortega, Ignacio, Gómez-Pulido, Federico, Grande-Ingelmo, Juan Manuel, Guasch-i-Casany, Eduard, Guerra-Ramos, José M., Heras-Herreros, Santiago, Hernández-Afonso, Julio, Herreros-Guilarte, Benito, Hidalgo-Olivares, Víctor Manuel, Ibáñez-Criado, Alicia, Ibáñez-Criado, José Luis, Ibars-Campaña, Sonia, Jáuregui-Abularach, Miguel Eduardo, Jiménez-Candil, F. Javier, Jiménez-Díaz, Javier, Jiménez-López, Jesús I., Lázaro-Rivera, Carla, Lozano-Herrera, José Miguel, Macías-Gallego, Alfonso, Magnani-Ragamato, Santiago, Martínez-Basterra, Javier, Martínez-Brotons, Ángel, Martínez-Sande, José Luis, Martín-Sánchez, Gabriel, Matías-Francés, Roberto, Merino-Llorens, José Luis, Mont-Girbau, Josep Lluis, Moreno-Arribas, José, Moreno-Planas, Javier, Moya-i-Mitjans, Ángel, Ortega-Molina, Marta, Osca-Asensi, Joaquín, Pastor-Fuentes, Agustín, Pavón-Jiménez, Ricardo, Peinado-Peinado, Rafael, Pérez-Álvarez, Luisa, Pérez-Castellano, Nicasio, Porro-Fernández, Rosa, Porta-Sánchez, Andreu, Punti-Sala, Jordi, Quesada-Dorador, Aurelio, Rivas-Gándara, Nuria, Rodrigo-Trallero, Gonzalo, Rodríguez-Entem, Felipe José, Rodríguez-Pérez, Juan Carlos, Romero-Garrido, Rafael, Rubín-López, José Manuel, Rubio-Caballero, José Amador, Rubio-Campal, José Manuel, Rubio-Sanz, Jerónimo, Ruiz-Hernández, Pablo M., Salgado-Aranda, Ricardo, Sánchez-Gómez, Juan Miguel, Sarquella-Brugada, Georgia, Sarrias-Mercé, Axel, Segura-Saint-Gerons, Jose María, Segura-Villalobos, Federico, Valverde-André, Irene, Ibáñez Criado, José Luis, Quesada, Aurelio, and Cózar, Rocío

Published
2019
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17. Registro Español de Ablación con Catéter. XVIII Informe Oficial de la Sección de Electrofisiología y Arritmias de la Sociedad Española de Cardiología (2018)

Author

Almendral-Garrote, Jesús, Alonso-Fernández, Pau, Alonso-Martín, Concepción, Alvarenga-Recalde, Nelson María, Álvarez-Acosta, Luis, Álvarez-López, Miguel, Anguera-Camos, Ignasi, Arana-Rueda, Eduardo, Arcocha-Torres, María Fe, Arias-Palomares, Miguel Ángel, Asso-Abadía, Antonio, Ballesteros-Derbenti, Gabriel Alejandro, Barrera-Cordero, Alberto, Benezet-Mazuecos, Juan, Bodegas-Cañas, Andrés I., Brugada-Terradellas, Josep, Cabadés-Rumbeu, Claudia, Cabanas-Grandío, María del Pilar, Cabrera-Gómez, Sandra, Cano-Calabria, Lucas R., del Castillo-Arrojo, Silvia, Castro-Urda, Víctor, Cózar-León, Rocío, Díaz-Infante, Ernesto, Durán-Guerrero, Juan Manuel, Elices-Teja, Juliana, Expósito-Pineda, María del Carmen, Fernández-Gómez, Juan Manuel, Ferrer-Hita, Julio Jesús, Fidalgo-Andrés, María Luisa, Fontenla-Cerezuela, Adolfo, García-Alberola, Arcadio, García-Bolao, J. Ignacio, García-Cuenca, Enrique, García-Fernández, Francisco Javier, Gil-Ortega, Ignacio, Gómez-Pulido, Federico, Grande-Ingelmo, Juan Manuel, Guasch-i-Casany, Eduard, Guerra-Ramos, José M., Heras-Herreros, Santiago, Hernández-Afonso, Julio, Herreros-Guilarte, Benito, Hidalgo-Olivares, Víctor Manuel, Ibáñez-Criado, Alicia, Ibáñez-Criado, José Luis, Ibars-Campaña, Sonia, Jáuregui-Abularach, Miguel Eduardo, Jiménez-Candil, F. Javier, Jiménez-Díaz, Javier, Jiménez-López, Jesús I., Lázaro-Rivera, Carla, Lozano-Herrera, José Miguel, Macías-Gallego, Alfonso, Magnani-Ragamato, Santiago, Martínez-Basterra, Javier, Martínez-Brotons, Ángel, Martínez-Sande, José Luis, Martín-Sánchez, Gabriel, Matías-Francés, Roberto, Merino-Llorens, José Luis, Mont-Girbau, Josep Lluis, Moreno-Arribas, José, Moreno-Planas, Javier, Moya-i-Mitjans, Ángel, Ortega-Molina, Marta, Osca-Asensi, Joaquín, Pastor-Fuentes, Agustín, Pavón-Jiménez, Ricardo, Peinado-Peinado, Rafael, Pérez-Álvarez, Luisa, Pérez-Castellano, Nicasio, Porro-Fernández, Rosa, Porta-Sánchez, Andreu, Punti-Sala, Jordi, Quesada-Dorador, Aurelio, Rivas-Gándara, Nuria, Rodrigo-Trallero, Gonzalo, Rodríguez-Entem, Felipe José, Rodríguez-Pérez, Juan Carlos, Romero-Garrido, Rafael, Rubín-López, José Manuel, Rubio-Caballero, José Amador, Rubio-Campal, José Manuel, Rubio-Sanz, Jerónimo, Ruiz-Hernández, Pablo M., Salgado-Aranda, Ricardo, Sánchez-Gómez, Juan Miguel, Sarquella-Brugada, Georgia, Sarrias-Mercé, Axel, Segura-Saint-Gerons, Jose María, Segura-Villalobos, Federico, Valverde-André, Irene, Ibáñez Criado, José Luis, Quesada, Aurelio, and Cózar, Rocío

Published
2019
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19. Registro español de ablación con catéter. XXII informe oficial de la Asociación del Ritmo Cardiaco de la Sociedad Española de Cardiología (2022)

Author

Cano, Óscar, primary, Bazán, Víctor, additional, Arana, Eduardo, additional, Alcalde-Rodríguez, Óscar, additional, Almendral-Garrote, Jesús, additional, Alonso-Fernández, Pau, additional, Álvarez-López, Miguel, additional, Álvarez-Acosta, Luis, additional, Anguera-Camos, Ignasi, additional, Arce-León, Álvaro, additional, Arenal, Ángel, additional, Palomares, Miguel Ángel Arias, additional, Arocha-Torres, María Fe, additional, Asso-Abadía, Antonio, additional, Barrera-Cordero, Alberto, additional, Bastos-Amador, Pablo, additional, Benezet-Mazuecos, Juan, additional, Benito-Martínez, Eva María, additional, Bochard-Villanueva, Bruno, additional, Cabanas-Grandío, Pilar, additional, Cabrera-Ramos, Mercedes, additional, Cano-Calabria, Lucas R., additional, del Castillo-Arrojo, Silvia, additional, Cerveró, Alba, additional, Datino-Romaniega, Tomás, additional, Díaz-Infante, Ernesto, additional, Domínguez-Mafé, Eloy, additional, Durán-Guerrero, Juan Manuel, additional, Teja, Juliana Elices, additional, Emilce-Trucco, María, additional, Espinosa-Viamonte, Hildemari, additional, Fabregat-Andrés, Óscar, additional, Fernández-Palacios, Gonzalo, additional, Fernández-Lozano, Ignacio, additional, Fernández-Gómez, Juan Manuel, additional, Ferrer-Hita, Julio Jesús, additional, Fidalgo-Andrés, María Luisa, additional, García-Cuenca, Enrique, additional, García-Rodríguez, Daniel, additional, García-Fernández, Francisco Javier, additional, Gil-Ortega, Ignacio, additional, Gómez-Pulido, Federico, additional, González-Ferrer, Juan José, additional, Grande-Morales, Carlos Eugenio, additional, Guasch-Casany, Eduard, additional, Guerra-Ramos, José María, additional, Herreros-Guilarte, Benito, additional, Hidalgo-Olivares, Víctor Manuel, additional, Ibáñez-Criado, Alicia, additional, Ibáñez-Criado, José Luis, additional, Jiménez-Díaz, Francisco Javier, additional, Jiménez-López, Jesús, additional, Jiménez-Candil, Javier, additional, Lozano-Granero, Vanesa Cristina, additional, Luque-Lezcano, Antonio Óscar, additional, Martí-Almor, Julio, additional, Martín-Sánchez, Gabriel, additional, Martínez-Sande, José Luis, additional, Martínez-Brotons, Ángel Miguel, additional, Mazuelos-Bellido, Francisco, additional, Mendoza-Lemes, Haridian, additional, Menéndez-Ramírez, Diego, additional, Merino-Llorens, José Luis, additional, Moreno-Arribas, José, additional, Moriña-Vázquez, Pablo, additional, Mosquera-Pérez, Ignacio, additional, Moya-Mitjans, Ángel, additional, Osca-Asensi, Joaquín, additional, Pastor-Fuentes, Agustín, additional, Pavón-Jiménez, Ricardo, additional, Pedrote-Martínez, Alonso, additional, Peinado-Peinado, Rafael, additional, Peláez-González, Antonio, additional, Peñafiel-Verdú, Pablo, additional, Pérez-Roselló, Víctor, additional, Porta-Sánchez, Andreu, additional, Portales-Fernández, Javier, additional, Quesada-Dorador, Aurelio, additional, Ramos-Ardanaz, Pablo, additional, Rivas-Gándara, Nuria, additional, Rodríguez-Entem, Felipe José, additional, Rodríguez-Font, Enrique, additional, Rodríguez-Muñoz, Daniel, additional, Romero-Garrido, Rafael, additional, Rubín-López, José Manuel, additional, Rubio-Caballero, José Amador, additional, Rubio-Campal, José Manuel, additional, Ruíz-Duthil, Ana Delia, additional, Ruíz-Hernández, Pablo M., additional, Sainz-Godoy, Íñigo, additional, Salgado-Aranda, Ricardo, additional, Salvador-Montañés, Óscar, additional, Sánchez-Borque, Pepa, additional, Sandín-Fuentes, María de Gracia, additional, Sarquella-Brugada, Georgia, additional, Sarrias-Mercè, Axel, additional, Saurí-Ortiz, Assumpció, additional, Segura-Villalobos, Federico, additional, Valverde-André, Irene, additional, and Vázquez-Esmorís, Iván, additional

Published
2023
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20. Plasma miR-486-5p Expression Is Upregulated in Atrial Fibrillation Patients with Broader Low-Voltage Areas

Author

Cebro-Márquez, María, primary, Rodríguez-Mañero, Moisés, additional, Serrano-Cruz, Valentina, additional, Vilar-Sánchez, Marta E., additional, González-Melchor, Laila, additional, García-Seara, Javier, additional, Martínez-Sande, José Luis, additional, Aragón-Herrera, Alana, additional, Martínez-Monzonís, María Amparo, additional, González-Juanatey, José Ramón, additional, Lage, Ricardo, additional, and Moscoso, Isabel, additional

Published
2023
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21. Validating Left Atrial Low Voltage Areas During Atrial Fibrillation and Atrial Flutter Using Multielectrode Automated Electroanatomic Mapping

Author

Rodríguez-Mañero, Moisés, Valderrábano, Miguel, Baluja, Aurora, Kreidieh, Omar, Martínez-Sande, Jose Luis, García-Seara, Javier, Saenen, Johan, Iglesias-Álvarez, Diego, Bories, Wim, Villamayor-Blanco, Luis Miguel, Pereira-Vázquez, María, Lage, Ricardo, Álvarez-Escudero, Julián, Heidbuchel, Hein, González-Juanatey, José Ramón, and Sarkozy, Andrea

Published
2018
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22. Updated performance of the Micra transcatheter pacemaker in the real-world setting: A comparison to the investigational study and a transvenous historical control

Author

El-Chami, Mikhael F., Al-Samadi, Faisal, Clementy, Nicolas, Garweg, Christophe, Martinez-Sande, Jose Luis, Piccini, Jonathan P., Iacopino, Saverio, Lloyd, Michael, Viñolas Prat, Xavier, Jacobsen, Michael Dilou, Ritter, Philippe, Johansen, Jens Brock, Tondo, Claudio, Liu, Fang, Fagan, Dedra H., Eakley, Alyssa K., and Roberts, Paul R.

Published
2018
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23. Spanish Catheter Ablation Registry. 17th Official Report of the Spanish Society of Cardiology Working Group on Electrophysiology and Arrhythmias (2017)

Author

Álvarez-López, Miguel, Almendral, Jesús, Alonso, Concepción, Alonso-Fernández, Pau, Alvaralenga, Nelson, Álvarez-Acosta, Luis, Anguera, Ignasi, Arcocha, María Fe, Arias, Miguel Ángel, Asso, Antonio, Barrera-Cordero, Alberto, Ballesteros, Gabriel, Benezet-Mazuecos, Juan, Bodegas-Cañas, Andrés, Brugada, Josep, Cabadés Lucas Cano-Calabria, Claudia, Caballero-Dorta, Eduardo, Cabanas-Grandío, Pilar, Cabrera, Sandra, Castro, Víctor, Cózar, Rocío, Díaz-Infante, Ernesto, Doblado, Manuel, Elices, Juliana, Expósito-Pineda, María del Carmen, Fernández-Gómez, Juan Manuel, Fidalgo, María Luisa, Fontenla, Adolfo, García-Fernández, F. Javier, García-Alberola, Arcadio, Gil-Ortega, Ignacio, Gómez-Pulido, Federico, González-Vasserot, Mar, Grande, Ángel, Guerra-Ramos, José M., Hernández-Afonso, Julio, Heras-Herreros, Santiago, Hidalgo-Olivares, Víctor Manuel, Ibáñez-Criado, José Luis, Ibáñez-Criado, Alicia, Ibars, Sonia, Jauregui, Miguel, Jiménez, Jesús, Jiménez-Díaz, Javier, Jiménez-Candil, Javier, Lázaro-Rivera, Carla, Mazuelos, Francisco, Magnani, Santiago, Martínez-Basterra, Javier, Macías, Alfonso, Martínez-Brotons, Ángel, Martínez-Sande, José Luis, Matía-Francés, Roberto, Moriña, Pablo, Moya, Ángel, Mont, Lluis, Moreno-Arribas, José, Moreno-Planas, Javier, Navarro-Manchón, Josep, Ortega-Molina, Marta, Osca, Joaquín, Pastor, Agustín, Pavón-Jiménez, Ricardo, Pedrote, Alonso, Peinado, Rafael, Pérez-Álvarez, Luisa, Pérez-Castellano, Nicasio, Pindado, Javier, Porro-Fernández, Rosa, Punti-Sala, Jordi, Quesada, Aurelio, Rivas-Gándara, Nuria, Rodrigo-Trallero, Gonzalo, Roca, Ivo, Rodríguez-Entem, Felipe, Rodríguez-Pérez, Juan Carlos, Rodríguez-Font, Enrique, Ruiz-Hernández, Pablo, Rubín, José Manuel, Rubio-Campal, José Manuel, Rubio-Caballero, Amador, Rubio-Sanz, Jerónimo, Salgado-Aranda, Ricardo, Sarrias, Axel, Sarquella-Brugada, Georgia, Esteban-Paul, Elena, Segura, Federico, Ibáñez Criado, José Luis, and Quesada Dorador, Aurelio

Published
2018
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24. Registro Español de Ablación con Catéter. XVII Informe Oficial de la Sección de Electrofisiología y Arritmias de la Sociedad Española de Cardiología (2017)

Author

Álvarez-López, Miguel, Almendral, Jesús, Alonso, Concepción, Alonso-Fernández, Pau, Alvaralenga, Nelson, Álvarez-Acosta, Luis, Anguera, Ignasi, Arcocha, María Fe, Arias, Miguel Ángel, Asso, Antonio, Barrera-Cordero, Alberto, Ballesteros, Gabriel, Benezet-Mazuecos, Juan, Bodegas-Cañas, Andrés, Brugada, Josep, Cano-Calabria, Claudia Cabadés Lucas, Caballero-Dorta, Eduardo, Cabanas-Grandío, Pilar, Cabrera, Sandra, Castro, Víctor, Cózar, Rocío, Díaz-Infante, Ernesto, Doblado, Manuel, Elices, Juliana, Expósito-Pineda, María del Carmen, Fernández-Gómez, Juan Manuel, Fidalgo, María Luisa, Fontenla, Adolfo, García-Fernández, F. Javier, García-Alberola, Arcadio, Gil-Ortega, Ignacio, Gómez-Pulido, Federico, González-Vasserot, Mar, Grande, Ángel, Guerra-Ramos, José M., Hernández-Afonso, Julio, Heras-Herreros, Santiago, Hidalgo-Olivares, Víctor Manuel, Ibáñez-Criado, José Luis, Ibáñez-Criado, Alicia, Ibars, Sonia, Jauregui, Miguel, Jiménez, Jesús, Jiménez-Díaz, Javier, Jiménez-Candil, Javier, Lázaro-Rivera, Carla, Mazuelos, Francisco, Magnani, Santiago, Martínez-Basterra, Javier, Macías, Alfonso, Martínez-Brotons, Ángel, Martínez-Sande, José Luis, Matía-Francés, Roberto, Moriña, Pablo, Moya, Ángel, Mont, Lluis, Moreno-Arribas, José, Moreno-Planas, Javier, Navarro-Manchón, Josep, Ortega-Molina, Marta, Osca, Joaquín, Pastor, Agustín, Pavón-Jiménez, Ricardo, Pedrote, Alonso, Peinado, Rafael, Pérez-Álvarez, Luisa, Pérez-Castellano, Nicasio, Pindado, Javier, Porro-Fernández, Rosa, Punti-Sala, Jordi, Quesada, Aurelio, Rivas-Gándara, Nuria, Rodrigo-Trallero, Gonzalo, Roca, Ivo, Rodríguez-Entem, Felipe, Rodríguez-Pérez, Juan Carlos, Rodríguez-Font, Enrique, Ruiz-Hernández, Pablo, Rubín, José Manuel, Rubio-Campal, José Manuel, Rubio-Caballero, Amador, Salgado-Aranda, Jerónimo Rubio-Sanz, Ricardo, Sarrias, Axel, Sarquella-Brugada, Georgia, Esteban-Paul, Elena, Segura, Federico, Ibáñez Criado, José Luis, and Quesada Dorador, Aurelio

Published
2018
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25. Role of Soluble ST2 Biomarker in Predicting Recurrence of Atrial Fibrillation after Electrical Cardioversion or Pulmonary Vein Isolation

Author

García-Seara, Javier, primary, González Melchor, Laila, additional, Rodríguez García, Javier, additional, Gude, Francisco, additional, Martínez Sande, José Luis, additional, Rodríguez Mañero, Moisés, additional, Fernández López, Xesús Alberte, additional, Minguito Carazo, Carlos, additional, González Ferrero, Teba, additional, Eiras, Sonia, additional, Lage, Ricardo, additional, Moscoso, Isabel, additional, Bandín, Sandra Feijoo, additional, Lago, Francisca, additional, Alvarez, Ezequiel, additional, Alvarez, Clara V., additional, and González Juanatey, José Ramón, additional

Published
2023
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26. Atrial fibrillation ablation in patients with arrhythmia‐induced cardiomyopathy: a prospective multicentre study

Author

González‐Ferrero, Teba, primary, Bergonti, Marco, additional, López‐Canoa, José Nicolás, additional, Arias, Federico García‐Rodeja, additional, Eiras Penas, Sonia, additional, Spera, Francesco, additional, González‐Maestro, Adrián, additional, Minguito‐Carazo, Carlos, additional, Martínez‐Sande, José Luis, additional, González‐Melchor, Laila, additional, García‐Seara, Francisco Javier, additional, Fernández‐López, Jesús Alberto, additional, Álvarez‐Castro, Ezequiel, additional, González‐Juanatey, José Ramón, additional, Heidbuchel, Hein, additional, Sarkozy, Andrea, additional, and Rodríguez‐Mañero, Moisés, additional

Published
2023
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27. Clinical profile and outcomes in octogenarians with atrial fibrillation: A community-based study in a specific European health care area

Author

Rodríguez-Mañero, Moisés, López-Pardo, Estrella, Cordero, Alberto, Kredieh, Omar, Pereira-Vazquez, María, Martínez-Sande, Jose-Luis, Martínez-Gomez, Alvaro, Peña-Gil, Carlos, Novo-Platas, José, García-Seara, Javier, Mazón, Pilar, Laje, Ricardo, Moscoso, Isabel, Varela-Román, Alfonso, García-Acuña, Jose María, and González-Juanatey, José Ramón

Published
2017
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28. Comparison and Validation of Recommended QT Interval Correction Formulas for Predicting Cardiac Arrhythmias in Patients With Advanced Heart Failure and Cardiac Resynchronization Devices

Author

Iglesias-Álvarez, Diego, Rodríguez-Mañero, Moisés, García-Seara, Francisco Javier, Kreidieh, Omar, Martínez-Sande, José Luis, Álvarez-Álvarez, Belén, Fernández-López, Xesús Alberte, González-Melchor, Laila, Lage-Fernández, Ricardo, Moscoso-Galán, Isabel, and González-Juanatey, José Ramón

Published
2017
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32. Plasma miR-486-5p Expression Is Upregulated in Atrial Fibrillation Patients with Broader Low-Voltage Areas

Author

Universidade de Santiago de Compostela. Centro de Investigación en Medicina Molecular e Enfermidades Crónicas, Universidade de Santiago de Compostela. Departamento de Bioquímica e Bioloxía Molecular, Cebro Márquez, María, Rodríguez Mañero, Moisés, Serrano Cruz, Valentina, Vilar Sánchez, Marta, González Melchor, Laila, García Seara, Javier, Martínez Sande, José Luis, Aragón Herrera, Alana, Martínez Monzonís, María Amparo, González Juanatey, José Ramón, Lage Fernández, Ricardo, Moscoso Galán, Isabel, Universidade de Santiago de Compostela. Centro de Investigación en Medicina Molecular e Enfermidades Crónicas, Universidade de Santiago de Compostela. Departamento de Bioquímica e Bioloxía Molecular, Cebro Márquez, María, Rodríguez Mañero, Moisés, Serrano Cruz, Valentina, Vilar Sánchez, Marta, González Melchor, Laila, García Seara, Javier, Martínez Sande, José Luis, Aragón Herrera, Alana, Martínez Monzonís, María Amparo, González Juanatey, José Ramón, Lage Fernández, Ricardo, and Moscoso Galán, Isabel

Abstract

Atrial fibrillation (AF) is the most common arrhythmia worldwide, affecting 1% of the population over 60 years old. The incidence and prevalence of AF are increasing globally, representing a relevant health problem, suggesting that more advanced strategies for predicting risk stage are highly needed. miRNAs mediate several processes involved in AF. Our aim was to identify miRNAs with a prognostic value as biomarkers in patients referred for AF ablation and its association with LVA extent, based on low-voltage area (LVA) maps. In this study, we recruited 44 AF patients referred for catheter ablation. We measured the expression of 84 miRNAs in plasma from peripheral blood in 3 different groups based on LVA extent. Expression analysis showed that miR-486-5p was significantly increased in patients with broader LVA (4-fold, p = 0.0002; 5-fold, p = 0.0001). Receiver operating characteristic curve analysis showed that miR-486-5p expression could predict atrium LVA (AUC, 0.8958; p = 0.0015). Also, miR-486-5p plasma levels were associated with AF-type (AUC, 0.7137; p = 0.0453). In addition, miR-486-5p expression was positively correlated with LVA percentage, left atrial (LA) area, and LA volume (r = 0.322, p = 0.037; r = 0.372, p = 0.015; r = 0.319, p = 0.045, respectively). These findings suggest that miR-486-5p expression might have prognostic significance in LVA extent in patients with AF

Published
2023

33. Circulating miR-451a Expression May Predict Recurrence in Atrial Fibrillation Patients after Catheter Pulmonary Vein Ablation

Author

Universidade de Santiago de Compostela. Centro de Investigación en Medicina Molecular e Enfermidades Crónicas, Universidade de Santiago de Compostela. Departamento de Bioquímica e Bioloxía Molecular, Lage Fernández, Ricardo, Cebro Márquez, María, Vilar Sánchez, Marta, González Melchor, Laila, García Seara, Javier, Martínez Sande, José Luis, Fernández López, Xesús Alberte, Aragón Herrera, Alana, Martínez Monzonís, María Amparo, González Juanatey, José Ramón, Rodríguez Mañero, Moisés, Moscoso Galán, Isabel, Universidade de Santiago de Compostela. Centro de Investigación en Medicina Molecular e Enfermidades Crónicas, Universidade de Santiago de Compostela. Departamento de Bioquímica e Bioloxía Molecular, Lage Fernández, Ricardo, Cebro Márquez, María, Vilar Sánchez, Marta, González Melchor, Laila, García Seara, Javier, Martínez Sande, José Luis, Fernández López, Xesús Alberte, Aragón Herrera, Alana, Martínez Monzonís, María Amparo, González Juanatey, José Ramón, Rodríguez Mañero, Moisés, and Moscoso Galán, Isabel

Abstract

Atrial fibrillation is the most prevalent tachyarrhythmia in clinical practice, with very high cardiovascular morbidity and mortality with a high-cost impact in health systems. Currently, it is one of the main causes of stroke and subsequent heart failure and sudden death. miRNAs mediate in several processes involved in cardiovascular disease, including fibrosis and electrical and structural remodeling. Several studies suggest a key role of miRNAs in the course and maintenance of atrial fibrillation. In our study, we aimed to identify the differential expression of circulating miRNAs and their predictive value as biomarkers of recurrence in atrial fibrillation patients undergoing catheter pulmonary vein ablation. To this effect, 42 atrial fibrillation patients were recruited for catheter ablation. We measured the expression of 84 miRNAs in non-recurrent and recurrent groups (45.2%), both in plasma from peripheral and left atrium blood. Expression analysis showed that miRNA-451a is downregulated in recurrent patients. Receiver operating characteristic curve analysis showed that miR-451a in left atrium plasma could predict atrial fibrillation recurrence after pulmonary vein isolation. In addition, atrial fibrillation recurrence is positively associated with the increment of scar percentage. Our data suggest that miRNA-451a expression plays an important role in AF recurrence by controlling fibrosis and progression

Published
2023

36. Circulating miR-451a Expression May Predict Recurrence in Atrial Fibrillation Patients after Catheter Pulmonary Vein Ablation

Author

Lage, Ricardo, primary, Cebro-Márquez, María, additional, Vilar-Sánchez, Marta E., additional, González-Melchor, Laila, additional, García-Seara, Javier, additional, Martínez-Sande, José Luis, additional, Fernández-López, Xesús Alberte, additional, Aragón-Herrera, Alana, additional, Martínez-Monzonís, María Amparo, additional, González-Juanatey, José Ramón, additional, Rodríguez-Mañero, Moisés, additional, and Moscoso, Isabel, additional

Published
2023
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42. The Role of Fatty Acid-Binding Protein 4 in the Characterization of Atrial Fibrillation and the Prediction of Outcomes after Catheter Ablation

Author

López-Canoa, José Nicolás, primary, Couselo-Seijas, Marinela, additional, González-Ferrero, Teba, additional, Almengló, Cristina, additional, Álvarez, Ezequiel, additional, González-Maestro, Adrián, additional, González-Melchor, Laila, additional, Martínez-Sande, José Luis, additional, García-Seara, Javier, additional, Fernández-López, Jesús, additional, Kreidieh, Bahij, additional, González-Babarro, Eva, additional, González-Juanatey, José Ramón, additional, Eiras, Sonia, additional, and Rodríguez-Mañero, Moisés, additional

Published
2022
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43. Circulating miR-499a and miR-125b as Potential Predictors of Left Ventricular Ejection Fraction Improvement after Cardiac Resynchronization Therapy

Author

Universidade de Santiago de Compostela. Centro de Investigación en Medicina Molecular e Enfermidades Crónicas, Universidade de Santiago de Compostela. Departamento de Bioquímica e Bioloxía Molecular, Moscoso Galán, Isabel, Cebro Márquez, María, Martínez Gómez, Álvaro, Abou Jokh Casas, Charigan, Martínez Monzonís, María Amparo, Martínez Sande, José Luis, González Melchor, Laila, García Seara, Javier, Fernández López, Xesús Alberte, Moraña Fernández, Sandra, González Juanatey, José Ramón, Rodríguez Mañero, Moisés, Lage Fernández, Ricardo, Universidade de Santiago de Compostela. Centro de Investigación en Medicina Molecular e Enfermidades Crónicas, Universidade de Santiago de Compostela. Departamento de Bioquímica e Bioloxía Molecular, Moscoso Galán, Isabel, Cebro Márquez, María, Martínez Gómez, Álvaro, Abou Jokh Casas, Charigan, Martínez Monzonís, María Amparo, Martínez Sande, José Luis, González Melchor, Laila, García Seara, Javier, Fernández López, Xesús Alberte, Moraña Fernández, Sandra, González Juanatey, José Ramón, Rodríguez Mañero, Moisés, and Lage Fernández, Ricardo

Abstract

Cardiac resynchronization therapy represents a therapeutic option for heart failure drug-refractory patients. However, due to the lack of success in 30% of the cases, there is a demand for an in-depth analysis of individual heterogeneity. In this study, we aimed to evaluate the prognostic value of circulating miRNA differences. Responder patients were defined by a composite endpoint of the presence of left ventricular reverse remodelling (a reduction ≥15% in telesystolic volume and an increment ≥10% in left ventricular ejection fraction). Circulating miRNAs signature was analysed at the time of the procedure and at a 6-month follow-up. An expression analysis showed, both at baseline and at follow-up, differences between responders and non-responders. Responders presented lower baseline expressions of miR-499, and at follow-up, downregulation of miR-125b-5p, both associated with a significant improvement in left ventricular ejection fraction. The miRNA profile differences showed a marked sensitivity to distinguish between responders and non-responders. Our data suggest that miRNA differences might contribute to prognostic stratification of patients undergoing cardiac resynchronization therapy and suggest that preimplant cardiac context as well as remodelling response are key to therapeutic success

Published
2022

47. Circulating miR-499a and miR-125b as Potential Predictors of Left Ventricular Ejection Fraction Improvement after Cardiac Resynchronization Therapy

Author

Moscoso, Isabel, primary, Cebro-Márquez, María, additional, Martínez-Gómez, Álvaro, additional, Abou-Jokh, Charigan, additional, Martínez-Monzonís, María Amparo, additional, Martínez-Sande, José Luis, additional, González-Melchor, Laila, additional, García-Seara, Javier, additional, Fernández-López, Xesús Alberte, additional, Moraña-Fernández, Sandra, additional, González-Juanatey, José R., additional, Rodríguez-Mañero, Moisés, additional, and Lage, Ricardo, additional

Published
2022
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48. Long-term cardiac reverse remodeling after cardiac resynchronization therapy

Author

Universidade de Santiago de Compostela. Departamento de Psiquiatría, Radioloxía, Saúde Pública, Enfermaría e Medicina, Álvarez Álvarez, Belén, García Seara, Francisco Javier, Martínez Sande, José Luis, Rodríguez Mañero, Moisés, Fernández López, Xesús Alberte, González Melchor, Laila, Iglesias Alvarez, Iglesias Álvarez, Diego, Gude Sampedro, Francisco, Díaz Louzao, Carla, González Juanatey, José Ramón, Universidade de Santiago de Compostela. Departamento de Psiquiatría, Radioloxía, Saúde Pública, Enfermaría e Medicina, Álvarez Álvarez, Belén, García Seara, Francisco Javier, Martínez Sande, José Luis, Rodríguez Mañero, Moisés, Fernández López, Xesús Alberte, González Melchor, Laila, Iglesias Alvarez, Iglesias Álvarez, Diego, Gude Sampedro, Francisco, Díaz Louzao, Carla, and González Juanatey, José Ramón

Abstract

Introduction: The benefit of cardiac resynchronization therapy (CRT) in heart failure (HF) patients with reduced left ventricular ejection fraction (LVEF) have been observed in the first year. However, there are few data on long-term follow-up and the effect of changes of LVEF on mortality. This study aimed to assess the LV remodeling after CRT implantation and the probable effect of changes in LVEF with repeated measures on mortality over time in a real-world registry. Methods: Among our cohort of 328 consecutive CRT patients, mixed model effect analysis have been made to describe the temporal evolution of LVEF and LVESV changes over time up with several explanatory variables. Besides, the effect of LVEF along time on the probability of mortality was evaluated using joint modeling for longitudinal and survival data. Results: The study population included 328 patients (253 men; 70.2 ± 9.5 years) in 4.2 (2.9) years follow-up. There was an increase in LVEF of 11% and a reduction in LVESV of 42 mL during the first year. These changes are more important during the first year, but slight changes remain during the follow-up. The largest reduction in LVESV occurred in patients with left bundle branch block (LBBB) and the smallest reduction in patients with NYHA IV. The smallest increase in LVEF was an ischemic etiology, longer QRS, and LV electrode in a nonlateral vein. Besides, the results showed that the LVEF profiles taken during follow-up after CRT were associated with changes in the risk of death. Conclusion: Reverse remodeling of the left ventricle is observed especially during the first year, but it seems to be maintained later after CRT implantation in a contemporary cohort of patients. Longitudinal measurements could give us additional information at predicting the individual mortality risk after adjusting by age and sex compared to a single LVEF measurement after CRT

Published
2021

49. Leadless pacemaker implantation with hybrid image mapping technique in a congenital heart disease case

Author

Universidade de Santiago de Compostela. Departamento de Psiquiatría, Radioloxía, Saúde Pública, Enfermaría e Medicina, Martínez Sande, José Luis, González Melchor, Laila, García Seara, Francisco Javier, Rodríguez Mañero, Moisés, Fernández López, Xesús Alberte, González Juanatey, José Ramón, Universidade de Santiago de Compostela. Departamento de Psiquiatría, Radioloxía, Saúde Pública, Enfermaría e Medicina, Martínez Sande, José Luis, González Melchor, Laila, García Seara, Francisco Javier, Rodríguez Mañero, Moisés, Fernández López, Xesús Alberte, and González Juanatey, José Ramón

Abstract

Sinus venosus atrial septal defect (SVASD) is an interatrial communication caused by a deficiency of the common wall between the superior vena cava and the right-sided pulmonary veins. Implantation of a conventional pacemaker in this setting can be challenging. We report the feasibility of leadless pacemaker (LPM) implantation assisted by imaging integration and electroanatomical mapping

Published
2021

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