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4. Candida spp. colonization: a genotype source found in blood cultures that can become widespread.

Author

Mesquida, Aina, Martín-Rabadán, Pablo, Alcalá, Luis, Burillo, Almudena, Reigadas, Elena, Muñoz, Patricia, Guinea, Jesús, and Escribano, Pilar

Subjects
MICROSATELLITE repeats, MEDICAL microbiology, URINARY organs, CANDIDEMIA, GASTROINTESTINAL system
Abstract

Objective: Our previous genotyping studies suggest that some anatomical locations act as reservoirs of genotypes that may cause further candidemia, since we found identical genotypes in gastrointestinal tract or catheter tip isolates and blood cultures, in contrast, we did not find blood culture genotypes in vagina samples. We observed that some genotypes can be found in blood cultures more frequently than others, some of them being called widespread genotypes because have been found in unrelated patients admitted to different hospitals. The presence of widespread genotypes may be more frequently found because of their predisposition to cause candidemia. It is unclear whether genotypes colonizing other anatomical sites different from the gastrointestinal tract can also be detected in this way; we studied C. albicans , C. parapsilosis , and C. tropicalis colonizing genotypes to assess what proportion could be found in blood cultures and the proportion of widespread genotypes. Methods: The isolates (n= 640 Candida isolates from 323 patients) studied herein were obtained from samples processed at the Clinical Microbiology and Infectious Diseases Department of the Gregorio Marañón Hospital (Madrid, Spain) from July 1, 2016, to June 30, 2019. C. albicans (n=486), C. parapsilosis (n=94), and C. tropicalis (n=60) isolates were genotyped using species-specific microsatellite markers and sourced from blood (n=120) and colonized anatomical sites (n=520; catheter [n=50], lower respiratory tract [n=227], skin/mucosa [n=132], and urinary tract [n=111]). Isolates with identical genotypes were those presenting the same alleles for all markers or with only differences at one locus of a given marker. Identical genotypes were further classified as a match (identical genotype found in different groups of samples from a given patient) or as a cluster (identical genotype found in ≥2 patients). Finally, singletons were genotypes detected once. The genotypes found were then compared with our in-house database containing 587 blood genotypes from patients admitted to the Gregorio Marañón Hospital (2007-2023) to assess the proportion of genotypes found in colonized samples that were also found in blood cultures. Moreover, since some of our in-house database genotypes had been tagged as widespread genotypes, we compared the proportions of widespread genotypes as well as the proportions of matches, clusters, and patients involved in clusters found among exclusively colonizing genotypes, exclusively blood culture genotypes, and both colonizing and blood culture genotypes using a standard binomial method. Results: Intra-patient analysis was conducted exclusively on those patients (n=225; 69.7%) who had ≥2 isolates from a given species; the proportion of patients with matches was lower in exclusively colonized patients than in patients with candidemia and colonizing genotypes (87.3% vs. 94.1%; p = 0.126). Inter-patient analysis was conducted considering all patients (n=323) and isolates from groups 1, 2, and 3 (n=640). Overall, we detected 341 genotypes, of which 320 were singletons and 21 were clusters (6.16%). Clusters involving blood cultures and colonizing isolates sourced from catheter tips (14.6%), skin and mucosa (7.5%), urine (7.4%), and lower respiratory tract (4.6%). Cluster-involved patients had not been admitted to the same ward at the same time. Of the 290 colonizing genotypes, 91 (31.1%) were also found in blood cultures, the highest proportion being C. parapsilosis (p < 0.05); proportions of identical genotypes found in blood cultures and catheter tips were higher than those found in blood cultures and other colonized samples (79.2% vs. 26.7%; p < 0.001). Widespread genotype ratios were significantly higher among genotypes found in both blood and colonized samples than among genotypes found exclusively in either blood culture or other colonizing genotypes (31.9% vs. 7.1% vs. 3.7%, respectively; p < 0.001). Conclusion: We observed that 94% of patients with candidemia were colonized by a genotype causing the infection; likewise, a total of 31% of colonizing genotypes were detectable in blood cultures. Finally, identical genotypes found in both colonized samples and blood cultures had a higher probability of being widespread. [ABSTRACT FROM AUTHOR]

Published
2024
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6. A multicentre analysis of Nocardia pneumonia in Spain: 2010–2016

Author

Ercibengoa, Maria, Càmara, Jordi, Tubau, Fe, García-Somoza, Dolores, Galar, Alicia, Martín-Rabadán, Pablo, Marin, Mercedes, Mateu, Lourdes, García-Olivé, Ignasi, Prat, Cristina, Cilloniz, Catia, Torres, Antonio, Pedro-Botet, Maria-Luisa, Ardanuy, Carmen, Muñoz, Patricia, and Marimón, Jose María

Published
2020
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8. Frequent Emergence of Resistance Mutations Following Complex Intra-Host Genomic Dynamics in SARS-CoV-2 Patients Receiving Sotrovimab

Author

Palomino-Cabrera, Rosalía, primary, Tejerina, Francisco, additional, Molero-Salinas, Andrea, additional, Ferris, María, additional, Veintimilla, Cristina, additional, Catalán, Pilar, additional, Rodríguez Macias, Gabriela, additional, Alonso, Roberto, additional, Muñoz, Patricia, additional, García de Viedma, Darío, additional, Pérez-Lago, Laura, additional, Alcalá, Luis, additional, Aldámiz, Teresa, additional, Álvarez-Uría, Ana, additional, Bermúdez, Elena, additional, Bouza, Emilio, additional, Buenestado-Serrano, Sergio, additional, Burillo, Almudena, additional, Carrillo, Raquel, additional, Cercenado, Emilia, additional, Cobos, Alejandro, additional, Díez, Cristina, additional, Escribano, Pilar, additional, Estévez, Agustín, additional, Fanciulli, Chiara, additional, Galar, Alicia, additional, García, Ma Dolores, additional, Gijón, Paloma, additional, Guillén, Helmuth, additional, Guinea, Jesús, additional, Herranz, Marta, additional, Irigoyen, Álvaro, additional, Kestler, Martha, additional, López, Juan Carlos, additional, Machado, Marina, additional, Marín, Mercedes, additional, Martín-Rabadán, Pablo, additional, Montilla, Pedro, additional, Padilla, Belén, additional, Palomino-Cabrera, Rosalía, additional, Palomo, María, additional, Pérez-Granda, María Jesús, additional, Peñas-Utrilla, Daniel, additional, Pérez, Leire, additional, Reigadas, Elena, additional, Rincón, Cristina, additional, Rodríguez, Belén, additional, Rodríguez, Sara, additional, Rodríguez-Grande, Cristina, additional, Rojas, Adriana, additional, Ruiz-Serrano, María Jesús, additional, Sánchez, Carlos, additional, Sánchez, Mar, additional, Sanz-Pérez, Amadeo, additional, Serrano, Julia, additional, Valerio, Maricela, additional, Veintimilla, Ma Cristina, additional, Vesperinas, Lara, additional, Vicente, Teresa, additional, and de la Villa, Sofía, additional

Published
2023
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13. Prevalence of submicroscopic malaria infection in immigrants living in Spain

Author

Fradejas, Isabel, Rubio, José Miguel, Martín-Díaz, Ariadna, Herrero-Martínez, Juan María, Ruiz-Giardin, José Manuel, Rojo-Marcos, Gerardo, Velasco, María, Calderón-Moreno, María, Azcona-Gutierrez, José Manuel, Merino, Francisco Jesús, Olmo, Belén Andrés, Espinosa, María, Cuadrado, María, González-Monte, Esther, Jaqueti, Jerónimo, Cuadros, Juan, Campelo, Carolina, Delgado-Iribarren, Alberto, Martín-Rabadán, Pablo, García-García, Concepción, Martín-Laso, María Ángeles, Valle-Borrego, Beatriz, García, María Coral, Lizasoaín, Manuel, and Pérez-Ayala, Ana

Published
2019
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17. Prevalence of Chagas disease in Latin American pregnant women in Madrid, Spain: A multicentre cross‐sectional study from 2011 to 2016.

Author

Herrero‐Martínez, Juan María, Trigo, Elena, Navarro, Miriam, García‐Alcázar, Diana, Carrillo, Irene, Fernández‐López, Tania, Calderón‐Moreno, María, Millán‐Pérez, Rosario, Cuadros, Juan, Velasco, María, García‐Bujalance, Silvia, Lizasoain, Manuel, Martín‐Rabadán, Pablo, Pérez‐Ayala, Ana, Flores‐Chávez, María, Aguado, Isabel, Aguinaga, Marisa, Álvaro, Miguel, Antón, Berta, and Arango, Esther

Subjects
CHAGAS' disease, DISEASE prevalence, MEDICAL screening, CROSS-sectional method, COUNTRY of origin (Immigrants)
Abstract

Objective: The aim of this study is to assess Trypanosoma cruzi infection prevalence among pregnant migrants living in Madrid according to the country of origin and to assess screening coverage in this at‐risk population. Methods: Retrospective multicentre cross‐sectional study conducted from January 2011 to December 2016 in eight Madrid hospitals. Each hospital reviewed their microbiology data records to assess the screening coverage and serological diagnosis in all pregnant women coming from endemic areas. Results: From 2011 to 2016, 149,470 deliveries were attended at the eight hospitals, and 11,048 pregnant women were screened for Chagas disease. Most cases (93.5%) were in women from Bolivia, who also showed the highest prevalence (12.4%, 95% confidence interval: 9.9–15.0). Pooled prevalence amongst the screened women was 2.9% (95% CI: 1.8–4.1). Chagas disease screening coverage varied greatly between centres, with a pooled mean coverage of 47% (95% CI: 37%–57%; 73% [95% CI: 63%–82%] for those centres with universal screening vs. 10% [95% CI: 6%–15%] for those with a selective screening approach; p < 0.001). Conclusion: Our study provides useful data for policy makers and epidemiologists in a non‐endemic area without congenital Chagas screening programmes. [ABSTRACT FROM AUTHOR]

Published
2023
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26. First Report of Neocucurbitaria unguis - hominis Keratitis.

Author

Sáenz-Madrazo, Nerea, Baeza, Azucena, Guinea, Jesús, Martín-Rabadán, Pablo, Ruiz-Velasco-Santacruz, Alejandro, and Urcelay, José Luis

Subjects
KERATITIS, CORNEAL ulcer, IDENTIFICATION of fungi, EMERGING infectious diseases, FILAMENTOUS fungi
Abstract

Coelomycetous fungi are among the emerging causes of infections and have been involved in many kinds of infections, including keratitis and endophtalmitis. Here, we present the first case of keratitis caused by Neocucurbitaria unguis-hominis, a coelomycetous fungus belonging to the family Cucurbitariaceae. In this case report, we describe the clinical presentation of a 56-year-old woman, a regular contact lens wearer, who was treated for pain in her right eye and fixed spot vision after an injury with plant debris. On examination, a corneal ulcer was observed, the foreign body was removed, and topical eye-drop therapy was started. After an initial improvement, the patient returned three weeks later due to a recurrence of discomfort in her right eye, observing the persistence of the corneal ulcer. Corneal scrapings were taken for culture, growing a filamentous fungus after seven days, which was identified by sequencing the fungal internal transcribed spacer region. It should be noted that microbiological identification of the coelomycetes in the clinical laboratory is not easy because of their difficulty in sporulating, making molecular techniques based on the amplification and sequencing of appropriate phylogenetic markers essential. Identification of these fungi is mandatory in order to optimise treatment due to the difficulty in eradicating them with antifungal treatment, requiring surgery in 50% of cases. [ABSTRACT FROM AUTHOR]

Published
2023
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27. Antifungal Susceptibility Testing Identifies the Abdominal Cavity as a Source of Candida glabrata-Resistant Isolates

Author

Díaz-García, Judith, primary, Mesquida, Aina, additional, Gómez, Ana, additional, Machado, Marina, additional, Martín-Rabadán, Pablo, additional, Alcalá, Luis, additional, Sánchez-Carrillo, Carlos, additional, Reigadas, Elena, additional, Vicente, Teresa, additional, Muñoz, Patricia, additional, Escribano, Pilar, additional, and Guinea, Jesús, additional

Published
2021
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33. Contributors

Author

Alangaden, George J., primary, Aldape, Michael J., additional, Allardet-Servent, Jérôme, additional, Allen, Upton D., additional, Ammerlaan, Heidi S.M., additional, Angelakis, Emmanouil, additional, Artenstein, Andrew, additional, Asboe, David, additional, Asiedu, Kingsley B., additional, Atherton, John C., additional, Aw, Tar-Ching, additional, Baid-Agrawal, Seema, additional, Bailey, Robin, additional, Bandel, Christopher, additional, Barie, Philip S., additional, Barillo, David J., additional, Bart, Pierre-Alexandre, additional, Bayston, Roger, additional, Beard, C. Ben, additional, Beeching, Nick J., additional, Bégué, Rodolfo E., additional, Benhamou, Yves, additional, Benson, Constance A., additional, Berbari, Elie F., additional, Berendt, Anthony R., additional, Bhatta, Madhav P., additional, Bille, Jacques, additional, Bitnun, Ari, additional, Black, Finn T., additional, Blair, Iain, additional, Blanche, Stéphane, additional, Bleck, Thomas P., additional, Bleeker-Rovers, Chantal P., additional, Bleijenberg, Gijs, additional, Bloch, Karen C., additional, Bonten, Marc J.M., additional, Boucher, Charles A.B., additional, Bourayou, Rafik, additional, Bouza, Emilio S., additional, Bowie, William R., additional, Brause, Barry D., additional, Brisse, Sylvain, additional, Britton, Warwick, additional, Brook, Itzhak, additional, Brown, David W.G., additional, Brun-Buisson, Christian, additional, Brust, James C.M., additional, Bryant, Amy E., additional, Bryskier, André, additional, Buller, R. Mark L, additional, Bush, Karen, additional, Calandra, Thierry, additional, Cameron, D. William, additional, Caraël, Michel, additional, Carr, Michael J., additional, Casas, Inmaculada, additional, Chambers, Stephen T., additional, Chiller, Katarina G., additional, Chiller, Tom M., additional, Chiodini, Peter L., additional, Chopra, Ian, additional, Chu, Anthony C., additional, Chung, Kevin K., additional, Clark, Benjamin M., additional, Clumeck, Nathan, additional, Cockerell, Clay J., additional, Cohen, Jonathan, additional, Collinge, John, additional, Conlon, Christopher P., additional, Corey, G. Ralph, additional, Cross, Alan, additional, Cross, John H., additional, Currier, Judith, additional, Curtis, Carmel M., additional, Dallabetta, Gina, additional, Davidson, Robert N., additional, Davies, Jane, additional, Day, Jeremy, additional, Day, Nicholas P.J., additional, De Gascun, Cillian F., additional, de Wit, Stéphane, additional, Delmont, Jean, additional, Dennis, David T., additional, Diemert, David J., additional, Doganay, Mehmet, additional, Doherty, Tom, additional, Dolecek, Christiane, additional, Donati, Stéphane Y., additional, Dondorp, Arjen M., additional, Doudier, Barbara, additional, Drancourt, Michel, additional, Drekonja, Dimitri M., additional, Drew, Richard H., additional, Duker, Jay S., additional, Dummer, J. Stephen, additional, Edwards, Charles N., additional, Ekkelenkamp, Miquel B., additional, Enright, Mark C., additional, Epstein, Paul R., additional, Erard, Veronique, additional, Eziefula, Alice Chijioke, additional, Feinberg, Mark B., additional, Fenollar, Florence, additional, Fenwick, Alan, additional, Fernandez, Luis, additional, Fierer, Joshua, additional, Finch, Roger G., additional, Flexner, Charles W., additional, Fluit, Ad C., additional, Ford-Jones, Elizabeth Lee, additional, Fournier, Pierre-Edouard, additional, Fraser, Victoria, additional, French, Martyn A., additional, Friedland, Jon S., additional, Fritz, Joseph M., additional, Furuya, E. Yoko, additional, Gage, Kenneth L., additional, Garcia, Lynne S., additional, Gastañaduy, Arturo S., additional, Ghanem, Khalil G., additional, Giannella, Maddalena, additional, Glaser, Carol A., additional, Glesby, Marshall J., additional, Glover, Sarah, additional, Glupczynski, Youri, additional, Gnann, John W., additional, Goddard, Andrew F., additional, Goldstein, Ellie J.C., additional, González, Iveth J., additional, Gorbach, Sherwood L., additional, Gottstein, Bruno, additional, Gowda, Ravi, additional, Grabenstein, John D., additional, Grange, John M., additional, Green, Michael D., additional, Green, Stephen T., additional, Greenblatt, Danielle T., additional, Greenwood, Brian, additional, Gregson, Aric L., additional, Groll, Andreas H., additional, Gupta, Aditya K., additional, Gwee, Kok-Ann, additional, Hall, William, additional, Hammer, Scott M., additional, Handa, Sajeev, additional, Hanfelt-Goade, Diane, additional, Harari, Alexandre, additional, Harris, Marianne, additional, Hartman, Barry J., additional, Hay, Roderick J., additional, Henderson, David K., additional, Hensley, Lisa E., additional, Herbert, Luke, additional, Hill, David R., additional, Hills, Timothy J., additional, Hinze, John David, additional, Hirsch, Hans H., additional, Hirschel, Bernard, additional, Hoepelman, Andy I.M., additional, Holland, Steven M., additional, Horgan, Mary M., additional, Howe, Robin, additional, Hughes, James M., additional, Hull, Mark W., additional, Inderlied, Clark B., additional, Ison, Michael G., additional, Jenks, Peter J., additional, Johnson, James R., additional, Jones, Theodore, additional, Kanno, Mettassebia, additional, Kauffman, Carol, additional, Kelly, Patrick, additional, Kendler, Jason S., additional, Keynan, Yoav, additional, Khan, Ali S., additional, Kho, Grace T., additional, Kinghorn, George R., additional, Klapper, Paul E., additional, Kluytmans, Jan AJW, additional, Kok, Menno, additional, Koné-Paut, Isabelle, additional, Krieger, John N., additional, Kroes, Aloys C.M., additional, Kroon, Frank P., additional, Kubin, Christine J., additional, La Rosa, Alberto M., additional, Lalani, Tahaniyat, additional, Lalloo, David G., additional, Lambert, Harold, additional, Landraud, Luce, additional, Lawn, Stephen D., additional, Pharm, Phillipe Lehours, additional, Leone, Marc, additional, Levi, Itzchak, additional, Levitt, Alexandra M., additional, Lindquist, H. D. Alan, additional, Lloyd, Graham, additional, Looney, David J., additional, Lowy, Franklin D., additional, Luft, Benjamin J., additional, Lynn, William A., additional, Macielag, Mark J., additional, Mackowiak, Philip A., additional, MacPherson, Paul A., additional, Maghraoui-Slim, Valérie, additional, Main, Janice, additional, Mallet, Vincent, additional, Mangino, Julie E., additional, Manuel, Oriol, additional, Marchetti, Oscar, additional, Marks, Kristen, additional, Marr, Kieren A., additional, Martin, Claude, additional, Martín-Rabadán, Pablo, additional, Martinez, Augusto Julio, additional, Mascini, Ellen M., additional, Mayer, Kenneth H., additional, McCormick, Joseph B., additional, McGready, Rose, additional, McKendrick, Michael W., additional, Mead, Simon, additional, Mégraud, Francis, additional, Meheus, André Z., additional, Meintjes, Graeme, additional, Michaels, Marian G., additional, Miles, Michael, additional, Miller, Alastair, additional, Mimiaga, Matthew J., additional, Mingeot-Leclercq, Marie-Paule, additional, Mitchell, Thomas G., additional, Moise, Pamela A., additional, Montaner, Julio, additional, Moore, Caroline B., additional, Moreillon, Philippe, additional, Morgan-Capner, Peter, additional, Montessori, Valentina, additional, Moss, Peter, additional, Muñoz, Patricia, additional, Naber, Kurt G., additional, Nakhla, Sammy, additional, Narain, Jai P., additional, Nathwani, Dilip, additional, Newton, Paul, additional, Nguyen, Chinh, additional, Nicolle, Lindsay E., additional, Niederman, Michael S., additional, Noel, Gary J., additional, Norrby, S. Ragnar, additional, Nosten, François, additional, Notarangelo, Luigi Daniele, additional, Nyirjesy, Paul, additional, O'Connell, P. Ronan, additional, Odorico, Jon S., additional, Ong, Edmund L.C., additional, Opal, Steven M., additional, Ormerod, L. Peter, additional, Osmon, Douglas R., additional, Ottesen, Eric A., additional, Palacios, Gustavo, additional, Pantaleo, Giuseppe, additional, Papazian, Laurent, additional, Parola, Philippe, additional, Pascual, Manuel A., additional, Patrozou, Eleni, additional, Paya, Carlos, additional, Peacock, Sharon J., additional, Pechère, Jean-Claude, additional, Perkins, Mark D., additional, Peters, Barry, additional, Pfyffer, Gaby E., additional, Pham, Paul A., additional, Piot, Peter, additional, Placko-Parola, Geraldine, additional, Pol, Stainslas, additional, Posfay-Barbe, Klara M., additional, Powderly, William G., additional, Pozniak, Anton, additional, Prod'hom, Guy, additional, Quinn, Thomas C., additional, Rahn, Daniel W., additional, Rana, Aadia I., additional, Raoult, Didier, additional, Raz, Raul, additional, Razonable, Raymund, additional, Read, Robert C., additional, Reynolds, Stephen J., additional, Richardson, Malcolm D., additional, Robinson, Christopher C., additional, Rooijakkers, Suzan H.M., additional, Rosenbluth, Daniel, additional, Rosenzweig, Sergio D., additional, Rovery, Clarisse, additional, Rubin, Robert H., additional, Rubinovitch, Bina, additional, Rubins, Kathleen H., additional, Rubinstein, Ethan, additional, Ryan, Greg, additional, Ryder, Stephen, additional, Safren, Steven, additional, Sahasrabuddhe, Vikrant V., additional, Saikku, Pekka A.I., additional, Sakoulas, George, additional, Salazar, Juan Carlos, additional, Salvaggio, Michelle R., additional, Schaffer, Kirsten, additional, Schmitz, Franz-Josef, additional, Schooley, Robert T., additional, Schumacher, Richard-Fabian, additional, Scrimgeour, Euan M., additional, Seddon, James, additional, Seifert, Harald, additional, Serjeant, Graham R., additional, Sha, Beverly E., additional, Shah, Keerti V., additional, Shapiro, Daniel S., additional, Sheehan, Gerard, additional, Shoham, Shmuel, additional, Simmons, Cameron P., additional, Simonsen, Kari A., additional, Singh, Neeraj, additional, Slack, Mary P.E., additional, Sobel, Jack D., additional, Sopirala, Madhuri M., additional, Spacek, Lisa A., additional, Sriskandan, Shiranee, additional, Stanley, Samuel L., additional, Steckelberg, James M., additional, Stephenson, Iain, additional, Stevens, Dennis L., additional, Straus, Walter L., additional, Sturm, Willem, additional, Summerbell, Richard C., additional, Susa, Joseph S., additional, Tabrizi, Sarah J., additional, Tack, Marc A., additional, Taplitz, Randy, additional, Tebas, Pablo, additional, Temmerman, Marleen, additional, Thijsen, Steven F.T., additional, Thomas, Lora D., additional, Thomson, Gail, additional, Thwaites, Guy E., additional, Tirelli, Umberto, additional, Tolkoff-Rubin, Nina E., additional, Tønjum, Tone, additional, Torriani, Francesca J., additional, Townsend, Gregory C., additional, Masó, Gloria Trallero, additional, Tulkens, Paul M., additional, Tunkel, Allan R., additional, Vaccher, Emanuela, additional, Vallet-Pichard, Anaïs, additional, Van Bambeke, Françoise, additional, van de Beek, Diederik, additional, van der Meer, Jos W.M., additional, van Loon, Anton M., additional, van Putten, Jos, additional, Vaudaux, Bernard P., additional, Vermund, Sten H., additional, Verstraelen, Hans, additional, Verweij, Paul, additional, Viscidi, Raphael P., additional, Visvanathan, Kumar, additional, Visvesvara, Govinda S., additional, von Seidlein, Lorenz, additional, Wagenlehner, Florian M.E., additional, Wahl-Jensen, Victoria, additional, Walsh, Thomas J., additional, Warhurst, David C., additional, Warnock, David W., additional, Warrell, David A., additional, Warrell, Mary J., additional, Warris, Adilia, additional, Weber, Rainer, additional, Weidner, Wolfgang, additional, Weston, Vivienne C., additional, Whimbey, Estella, additional, Whitby, Michael, additional, White, Peter J., additional, Whitty, Christopher J.M., additional, Willems, Rob J.L., additional, Williams, Emrys, additional, Wilson, Cara, additional, Wilson, Mary E., additional, Winn, Richard E., additional, Winthrop, Kevin L., additional, Wiselka, Martin J., additional, Wisplinghoff, Hilmar, additional, Wolfe, Cameron R., additional, Wood, Robin, additional, Wright, Natalie, additional, Yankaskas, James R., additional, Zaidi, Najam A., additional, Zenilman, Jonathan M., additional, Zhang, Yaobi, additional, Zuckerman, Arie J., additional, Zuckerman, Jane Nicola, additional, and Zumla, Alimuddin, additional

Published
2010
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38. MOESM4 of Prevalence of submicroscopic malaria infection in immigrants living in Spain

Author

Fradejas, Isabel, Rubio, José, Martín-Díaz, Ariadna, Herrero-Martínez, Juan, Ruiz-Giardin, José, Rojo-Marcos, Gerardo, Velasco, María, Calderón-Moreno, María, Azcona-Gutierrez, José, Merino, Francisco, Olmo, Belén, Espinosa, María, Cuadrado, María, González-Monte, Esther, Jaqueti, Jerónimo, Cuadros, Juan, Campelo, Carolina, Delgado-Iribarren, Alberto, Martín-Rabadán, Pablo, García-García, Concepción, Martín-Laso, María, Valle-Borrego, Beatriz, García, María, Lizasoaín, Manuel, and Pérez-Ayala, Ana

Subjects
parasitic diseases
Abstract

Additional file 4: Table S4. Co-morbidities and other infectious diseases of the 109 patients with microscopic malaria.

Published
2019
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39. Etiology and Prognosis of Pneumonia in Patients with Solid Tumors: A Prospective Cohort of Hospitalized Cases

Author

Fernández-Cruz, Ana, primary, Ortega, Laura, additional, García, Gonzalo, additional, Gallego, Iria, additional, Álvarez-Uría, Ana, additional, Chamorro-de-Vega, Esther, additional, García-López, José Javier, additional, González-del-Val, Ricardo, additional, Martín-Rabadán, Pablo, additional, Rodríguez, Carmen, additional, Pedro-Botet, María Luisa, additional, Martín, Miguel, additional, and Bouza, Emilio, additional

Published
2020
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41. Fatal disseminated infection byGymnascella hyalinosporain a heart transplant recipient

Author

Agnelli, Caroline, primary, Valerio, Maricela, additional, Olmedo, María, additional, Guinea, Jesús, additional, Zatarain‐Nicolás, Eduardo, additional, del Carmen Martínez‐Jiménez, María, additional, Alcalá, Luis, additional, Escribano, Pilar, additional, Cebollero Presmanes, María, additional, Bouza, Emilio, additional, Muñoz, Patricia, additional, and Martín‐Rabadán, Pablo, additional

Published
2019
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43. Susceptibility of uncommon Candida species to systemic antifungals by the EUCAST methodology.

Author

Díaz-García, Judith, Alcalá, Luis, Martín-Rabadán, Pablo, Mesquida, Aina, Sánchez-Carrillo, Carlos, Reigadas, Elena, Muñoz, Patricia, Escribano, Pilar, and Guinea, Jesús

Abstract

The incidence of infections by uncommon Candida species has increased in recent years, however, in vitro susceptibility data are scarce. Here we assess the susceptibility of C. krusei, C. dubliniensis, C. lusitaniae , and C. guilliermondii complex isolates (n  = 120) to antifungal agents by the EUCAST methodology. C. dubliniensis proved to be the most susceptible species, similar to that of C. albicans (P  < .05), whereas C. guilliermondii was the least susceptible. Two C. krusei isolates were echinocandin-resistant and harbored a point mutation (L701M) in the FKS1. Some isolates were either fluconazole-resistant (C. lusitaniae, n  = 2) or fluconazole non-wild type (C. guilliermondii, n  = 3). [ABSTRACT FROM AUTHOR]

Published
2020
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48. In Reply

Author

Guembe, María, primary, Martín-Rabadán, Pablo, additional, Cruces, Raquel, additional, Pérez Granda, María Jesús, additional, and Bouza, Emilio, additional

Published
2017
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