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483 results on '"Marrone, Aldo"'

1. A holistic evaluation of patients with chronic Hepatitis D virus (HDV) infection enrolled in the Italian PITER-B and delta cohort

Author

Aghemo, Alessio, Baiguera, Chiara, Battezzati, Pier Maria, Battistella, Sara, Bavetta, Maria Grazia, Bertoni, Costanza, Boni, Carolina, Brambilla, Paola, Bray, Antonella, Briano, Federica, Carmenini, Enrico, Castelli, Francesco, Cavalletto, Luisa, Cerini, Federica, Chidichimo, Luciana, Colella, Elisa, Cologni, Giuliana, Como, Silvia, Corsini, Romina, Costa, Chiara, Cotugno, Rosa, Cretella, Silvia, De Angelis, Fernando, De Leo, Pasqualina, Perri, Giovanni Di, Falbo, Elisabetta, Ferrigno, Luigina, Fornasiere, Ezio, Francisci, Daniela, Gatti, Pietro, Lampertico, Pietro, Lenci, Ilaria, Licata, Anna, Maida, Ivana, Marzano, Alfredo, Mastroianni, Antonio, Mazzaro, Cesare, Monti, Monica, Nardone, Gerardo, Nicolini, Laura Ambra, Passigato, Nicola, Pasticci, Maria Bruna, Pierotti, Piera, Pinchera, Biagio, Pollicino, Teresa, Porcu, Carmen, Quartini, Giulia, Rancatore, Gabriele, Romeo, Mario, Rumi, Maria Grazia, Saracino, Annalisa, Schioppa, Ornella, Serio, Ilaria, Soffredini, Roberta, Tata, Xhimi, Tizzani, Marco, Tonnini, Matteo, Torti, Carlo, Valenti, Daniela, Zaltron, Serena, Zoncada, Alessia, Kondili, Loreta A., Brancaccio, Giuseppina, Tosti, Maria Elena, Coco, Barbara, Quaranta, Maria Giovanna, Messina, Vincenzo, Ciancio, Alessia, Morisco, Filomena, Cossiga, Valentina, Claar, Ernesto, Rosato, Valerio, Ciarallo, Marianna, Cacciola, Irene, Ponziani, Francesca Romana, Cerrito, Lucia, Coppola, Roberta, Longobardi, Francesco, Biliotti, Elisa, Rianda, Alessia, Barbaro, Francesco, Coppola, Nicola, Stanzione, Maria, Barchiesi, Francesco, Fagiuoli, Stefano, Viganò, Mauro, Massari, Marco, Russo, Francesco Paolo, Ferrarese, Alberto, Laccabue, Diletta, Di Marco, Vito, Blanc, Pierluigi, Marrone, Aldo, Morsica, Giulia, Federico, Alessandro, Ieluzzi, Donatella, Rocco, Alba, Foschi, Francesco Giuseppe, Soria, Alessandro, Chessa, Luchino, Milella, Michele, Rosselli Del Turco, Elena, Madonia, Salvatore, Chemello, Liliana, Gentile, Ivan, Toniutto, Pierluigi, Bassetti, Matteo, Surace, Lorenzo, Baiocchi, Leonardo, Pellicelli, Adriano, De Santis, Adriano, Puoti, Massimo, Degasperi, Elisabetta, Niro, Grazia Anna, Zignego, Anna Linda, Craxi, Antonio, Raimondo, Giovanni, Santantonio, Teresa Antonia, Brunetto, Maurizia Rossana, and Gaeta, Giovanni Battista

Published
2024
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2. Mortality and risk factors of vaccinated and unvaccinated frail patients with COVID-19 treated with anti-SARS-CoV-2 monoclonal antibodies: A real-world study

Author

Nevola, Riccardo, Feola, Giovanni, Ruocco, Rachele, Russo, Antonio, Villani, Angela, Fusco, Raffaele, De Pascalis, Stefania, Core, Micol Del, Cirigliano, Giovanna, Pisaturo, Mariantonietta, Loffredo, Giuseppe, Rinaldi, Luca, Marrone, Aldo, Starace, Mario, Sposito, Pellegrino De Lucia, Cozzolino, Domenico, Salvatore, Teresa, Lettieri, Miriam, Marfella, Raffaele, Sasso, Ferdinando Carlo, Coppola, Nicola, and Adinolfi, Luigi Elio

Published
2023
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3. Trends in chronic hepatitis B virus infection in Italy over a 10-year period: Clues from the nationwide PITER and MASTER cohorts toward elimination

Author

Pasulo, Luisa, Coppola, Carmine, Pisano, Federica, Romano, Mariarosaria, Porcu, Carmen, Bottalico, Irene Francesca, Cossiga, Valentina, Tata, Xhimi, Sagnelli, Caterina, Pierotti, Piera, Degasperi, Elisabetta, Rosato, Valerio, Badia, Lorenzo, Ieluzzi, Dontella, Monti, Monica, Bavetta, Maria Grazia, Cavalletto, Luisa, Toniutto, Pierluigi, Fornasiere, Ezio, Colecchia, Antonio, Ferrarese, Alberto, Nardone, Gerardo, Rocco, Alba, Viganò, Mauro, Foschi, Francesco Giuseppe, Conti, Fabio, Morsica, Giulia, Salpietro, Stefania, Torti, Carlo, Costa, Chiara, Federico, Alessandro, Dallio, Marcello, Giorgini, Alessia, Anselmo, Marco, De Leo, Pasqualina, Zaltron, Serena, Cambianica, Anna, Piscaglia, Fabio, Serio, Ilaria, Schivazappa, Simona, Mastroianni, Antonio, Chidichimo, Luciana, Massari, Marco, Mazzaro, Cesare, Marrone, Aldo, D'Amore, Francesca Maria, D'Offizi, Gianpiero, Licata, Anna, Niro, Grazia Anna, Pollicino, Teresa, Aghemo, Alessio, Brancaccio, Giuseppina, Coco, Barbara, Nardi, Alessandra, Quaranta, Maria Giovanna, Tosti, Maria Elena, Ferrigno, Luigina, Cacciola, Irene, Messina, Vincenzo, Chessa, Luchino, Morisco, Filomena, Milella, Michele, Barbaro, Francesco, Ciancio, Alessia, Russo, Francesco Paolo, Coppola, Nicola, Blanc, Pierluigi, Claar, Ernesto, Verucchi, Gabriella, Puoti, Massimo, Zignego, Anna Linda, Chemello, Liliana, Madonia, Salvatore, Fagiuoli, Stefano, Marzano, Alfredo, Ferrari, Carlo, Lampertico, Pietro, Di Marco, Vito, Craxì, Antonio, Santantonio, Teresa Antonia, Raimondo, Giovanni, Brunetto, Maurizia R., Gaeta, Giovanni Battista, and Kondili, Loreta A.

Published
2023
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6. Non-invasive respiratory support in SARS-CoV-2 related acute respiratory distress syndrome: when is it most appropriate to start treatment?

Author

Nevola, Riccardo, Russo, Antonio, Scuotto, Samuel, Imbriani, Simona, Aprea, Concetta, Abitabile, Marianna, Beccia, Domenico, Brin, Chiara, Carusone, Caterina, Cinone, Francesca, Cirigliano, Giovanna, Colantuoni, Sara, Cozzolino, Domenico, Cuomo, Giovanna, Del Core, Micol, Gjeloshi, Klodian, Marrone, Aldo, Medicamento, Giulia, Meo, Luciana Agnese, Nappo, Francesco, Padula, Andrea, Pafundi, Pia Clara, Ranieri, Roberta, Ricozzi, Carmen, Rinaldi, Luca, Romano, Ciro Pasquale, Ruocco, Rachele, Ruosi, Carolina, Salvati, Annabella, Sasso, Ferdinando Carlo, Sellitto, Ausilia, Sommese, Pino, Villani, Angela, Coppola, Nicola, and Adinolfi, Luigi Elio

Published
2022
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7. A holistic evaluation of patients with chronic Hepatitis D virus (HDV) infection enrolled in the Italian PITER-B and Delta cohort

Author

Kondili, Loreta A., primary, Brancaccio, Giuseppina, additional, Tosti, Maria Elena, additional, Coco, Barbara, additional, Quaranta, Maria Giovanna, additional, Messina, Vincenzo, additional, Ciancio, Alessia, additional, Morisco, Filomena, additional, Cossiga, Valentina, additional, Claar, Ernesto, additional, Rosato, Valerio, additional, Ciarallo, Marianna, additional, Cacciola, Irene, additional, Ponziani, Francesca Romana, additional, Cerrito, Lucia, additional, Coppola, Roberta, additional, Longobardi, Francesco, additional, Biliotti, Elisa, additional, Rianda, Alessia, additional, Barbaro, Francesco, additional, Coppola, Nicola, additional, Stanzione, Maria, additional, Barchiesi, Francesco, additional, Fagiuoli, Stefano, additional, Viganò, Mauro, additional, Massari, Marco, additional, Russo, Francesco Paolo, additional, Ferrarese, Alberto, additional, Laccabue, Diletta, additional, Marco, Vito Di, additional, Blanc, Pierluigi, additional, Marrone, Aldo, additional, Morsica, Giulia, additional, Federico, Alessandro, additional, Ieluzzi, Donatella, additional, Rocco, Alba, additional, Foschi, Francesco Giuseppe, additional, Soria, Alessandro, additional, Maida, Ivana, additional, Chessa, Luchino, additional, Milella, Michele, additional, Turco, Elena Rosselli del, additional, Madonia, Salvatore, additional, Chemello, Liliana, additional, Gentile, Ivan, additional, Toniutto, Pierluigi, additional, Bassetti, Matteo, additional, Surace, Lorenzo, additional, Baiocchi, Leonardo, additional, Pellicelli, Adriano, additional, De Santis, Adriano, additional, Puoti, Massimo, additional, Degasperi, Elisabetta, additional, Niro, Grazia Anna, additional, Zignego, Anna Linda, additional, Craxi, Antonio, additional, Raimondo, Giovanni, additional, Santantonio, Teresa Antonia, additional, Brunetto, Maurizia Rossana, additional, Gaeta, Giovanni Battista, additional, and Investigators, on behalf of PITER Collaborating, additional

Published
2024
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8. Viral Hepatitis C

Author

Adinolfi, Luigi Elio, Mangoni, Emanuele Durante, Marrone, Aldo, Zampino, Rosa, Rinaldi, Luca, Radu-Ionita, Florentina, editor, Pyrsopoulos, Nikolaos T., editor, Jinga, Mariana, editor, Tintoiu, Ion C., editor, Sun, Zhonghua, editor, and Bontas, Ecaterina, editor

Published
2020
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9. Hepatitis C Virus (HCV) Infection: Pathogenesis, Oral Manifestations, and the Role of Direct-Acting Antiviral Therapy: A Narrative Review.

Author

Di Stasio, Dario, Guida, Agostino, Romano, Antonio, Petruzzi, Massimo, Marrone, Aldo, Fiori, Fausto, and Lucchese, Alberta

Subjects
ORAL lichen planus, HEPATITIS C virus, DENTAL pathology, NARRATIVE therapy, ORAL diseases
Abstract

Hepatitis C virus (HCV) infection is a global health concern with significant systemic implications, including a range of oral manifestations. This review aims to provide a comprehensive overview of the oral and dental pathologies related to HCV, the etiopathogenetic mechanisms linking such conditions to HCV and the impact of direct-acting antiviral (DAA) therapy. Common oral manifestations of HCV include oral lichen planus (OLP), periodontal disease, and xerostomia. The pathogenesis of these conditions involves both direct viral effects on oral tissues and indirect effects related to the immune response to HCV. Our literature analysis, using PubMed, Scopus, Web of Science, and Google Scholar, suggests that both the HCV infection and the immune response to HCV contribute to the increased prevalence of these oral diseases. The introduction of DAA therapy represents a significant advancement in HCV treatment, but its effects on oral manifestations, particularly OLP, are still under evaluation. Although a possible mechanism linking HCV to OSCC is yet to be determined, existing evidence encourages further investigation in this sense. Our findings highlight the need for established protocols for managing the oral health of patients with HCV, aiming to improve outcomes and quality of life. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Impact of chronic liver disease on SARS-CoV-2 infection outcomes: Roles of stage, etiology and vaccination

Author

Nevola, Riccardo, Criscuolo, Livio, Beccia, Domenico, Delle Femine, Augusto, Ruocco, Rachele, Imbriani, Simona, Alfano, Maria, Villani, Angela, Russo, Antonio, Perillo, Pasquale, Marfella, Raffaele, Adinolfi, Luigi Elio, Sasso, Ferdinando Carlo, Marrone, Aldo, Rinaldi, Luca, Nevola, Riccardo, Criscuolo, Livio, Beccia, Domenico, Delle Femine, Augusto, Ruocco, Rachele, Imbriani, Simona, Alfano, Maria, Villani, Angela, Russo, Antonio, Perillo, Pasquale, Marfella, Raffaele, Adinolfi, Luigi Elio, Sasso, Ferdinando Carlo, Marrone, Aldo, and Rinaldi, Luca

Subjects
Cirrhosi, SARS-CoV-2 infection, Chronic liver disease, Gastroenterology, COVID-19, General Medicine, Liver injury, Non-alcoholic fatty liver disease
Abstract

Since the first identification in December of 2019 and the fast spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, it has represented a dramatic global public health concern. Though affecting mainly the respiratory system, SARS-CoV-2 disease, defined as coronavirus disease 2019 (COVID-19), may have a systemic involvement leading to multiple organ dysfunction. Experimental evidence about the SARS-CoV-2 tropism for the liver and the increasing of hepatic cytolysis enzymes during infection support the presence of a pathophysiological relationship between liver and SARS-CoV-2. On the other side, patients with chronic liver disease have been demonstrated to have a poor prognosis with COVID-19. In particular, patients with liver cirrhosis appear extremely vulnerable to infection. Moreover, the etiology of liver disease and the vaccination status could affect the COVID-19 outcomes. This review analyzes the impact of the disease stage and the related causes on morbidity and mortality, clinical outcomes during SARS-CoV-2 infection, as well as the efficacy of vaccination in patients with chronic liver disease.

Published
2023

12. Liver Involvement during SARS-CoV-2 Infection Is Associated with a Worse Respiratory Outcome in COVID-19 Patients

Author

Romano, Ciro, primary, Cozzolino, Domenico, additional, Nevola, Riccardo, additional, Abitabile, Marianna, additional, Carusone, Caterina, additional, Cinone, Francesca, additional, Cuomo, Giovanna, additional, Nappo, Francesco, additional, Sellitto, Ausilia, additional, Umano, Giuseppina Rosaria, additional, Adinolfi, Luigi Elio, additional, Marrone, Aldo, additional, and Rinaldi, Luca, additional

Published
2023
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13. Hepatitis C virus eradication by direct-acting antiviral agents improves carotid atherosclerosis in patients with severe liver fibrosis

Author

Petta, Salvatore, Adinolfi, Luigi Elio, Fracanzani, Anna Ludovica, Rini, Francesca, Caldarella, Rosalia, Calvaruso, Vincenza, Cammà, Calogero, Ciaccio, Marcello, Di Marco, Vito, Grimaudo, Stefania, Licata, Anna, Marrone, Aldo, Nevola, Riccardo, Pipitone, Rosaria Maria, Pinto, Antonio, Rinaldi, Luca, Torres, Daniele, Tuttolomondo, Antonino, Valenti, Luca, Fargion, Silvia, and Craxì, Antonio

Published
2018
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15. Long-Term Prognosis among COVID-19 Patients: The Predictive Role Played by Hyperinflammation and Arrhythmic Disorders in Fatal Outcome

Author

Cozzolino, Domenico, primary, Romano, Ciro, additional, Sardu, Celestino, additional, Nevola, Riccardo, additional, Umano, Giuseppina Rosaria, additional, Rinaldi, Luca, additional, Adinolfi, Luigi Elio, additional, Catalini, Christian, additional, Marrone, Aldo, additional, Municinò, Maurizio, additional, Sasso, Ferdinando Carlo, additional, and Marfella, Raffaele, additional

Published
2023
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16. Gender Differences in the Pathogenesis and Risk Factors of Hepatocellular Carcinoma

Author

Nevola, Riccardo, primary, Tortorella, Giovanni, additional, Rosato, Valerio, additional, Rinaldi, Luca, additional, Imbriani, Simona, additional, Perillo, Pasquale, additional, Mastrocinque, Davide, additional, La Montagna, Marco, additional, Russo, Antonio, additional, Di Lorenzo, Giovanni, additional, Alfano, Maria, additional, Rocco, Maria, additional, Ricozzi, Carmen, additional, Gjeloshi, Klodian, additional, Sasso, Ferdinando Carlo, additional, Marfella, Raffaele, additional, Marrone, Aldo, additional, Kondili, Loreta Anesti, additional, Esposito, Nicolino, additional, Claar, Ernesto, additional, and Cozzolino, Domenico, additional

Published
2023
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17. Epidemiological and clinical profile of HDV infected people in care in Italy: interim analysis from the ongoing PITER cohort

Author

Kondili, Loreta, primary, Tosti, Maria Elena, additional, Quaranta, Maria Giovanna, additional, Ciancio, Alessia, additional, Messina, Vincenzo, additional, Brancaccio, Giuseppina, additional, Brunetto, Maurizia, additional, Capasso, Mario, additional, Rosato, Valerio, additional, Cacciola, Irene, additional, Pasulo, Luisa, additional, Santantonio, Teresa, additional, Coppola, Carmine, additional, Biliotti, Elisa, additional, Barbaro, Francesco, additional, Massari, Marco, additional, Coppola, Nicola, additional, Ferrarese, Alberto, additional, Russo, Francesco Paolo, additional, Di Marco, Vito, additional, Marrone, Aldo, additional, Schivazappa, Simona, additional, Federico, Alessandro, additional, Blanc, Pierluigi, additional, Rocco, Alba, additional, Morsica, Giulia, additional, Ieluzzi, Donatella, additional, Conti, Fabio, additional, De Siena, Martina, additional, Bavetta, Maria Grazia, additional, Milella, Michele, additional, Gentile, Ivan, additional, Porcu, Carmen, additional, Chemello, Liliana, additional, Maracci, Monia, additional, Zignego, Anna Linda, additional, Baiocchi, Leonardo, additional, Maida, Ivana Rita, additional, and Coco, Barbara, additional

Published
2023
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18. Ombitasvir, paritaprevir, and ritonavir, with or without dasabuvir, plus ribavirin for patients with hepatitis C virus genotype 1 or 4 infection with cirrhosis (ABACUS): a prospective observational study

Author

Tabone, Marco, Andreoni, Massimo, Teti, Elisabetta, Angelico, Mario, Persico, Marcello, Masarone, Mario, Chiodera, Aledssandro, Solinas, Attilio, delle Monache, Marco, Cecere, Roberto, Maria Schimizzi, Anna, Piovesan, Sara, Campagnolo, Davide, Chiara Piras, Maria, Zolfino, Teresa, Paolo Russo, Francesca, Morelli, Olivia, Sangiovanni, Vincenzo, Onofrio, Mirella, Iodice, Valentina, Izzi, Antonio, Pirisi, Massimo, Danieli, Elena, Vinci, Maria, Rizzardini, Giuliano, Fagiuoli, Stefano, Pasulo, Luisa, D'Arminio Monforte, Antonella, Zuin, Massimo, Giorgini, Alessia, Simeone, Filomena, Piali, Guido, Lo Guercio, Carmela, Federico, Alessandro, Brancaccio, Giuseppina, Marrone, Aldo, Abbati, Giuseppe, Boarini, Chiara, Borghi, Vanni, Bernabucci, Veronica, Corti, Giampaolo, Monti, Monica, Rizzetto, Mario, Martini, Silvia, Andreone, Pietro, Gianstefani, Alice, Lenzi, Marco, Verucchi, Gabriella, Toniutto, Pierluigi, Borgia, Guglielmo, Caporaso, Nicola, Morisco, Filomena, Nardone, Gaetano, Angrisani, Debora, Giacometti, Andrea, Benedetti, Antonio, Tarantino, Giuseppe, Marsetti, Fabio, Tavio, Marcello, Novara, Sergio, Antonia Santantonio, Teresa, Serviddio, Gaetano, Brunetto, Maurizia, Coco, Barbara, Angarano, Gioacchino, Milella, Michele, Barone, Michele, Di Leo, Alfredo, Ettore Sansonno, Domenico, Cacciola, Irene, Boffa, Nicola, Saracco, Giorgio, Di Biagio, Antonio, Picciotto, Antonino, de Luca, Andrea, Calvaruso, Vincenza, Corradori, Silvia, Ferrari, Carlo, Orlandini, Alessandra, Maida, Ivana, Torti, Carlo, Chessa, Luchino, Felder, Martina, Vespasiani Gentilucci, Umberto, Angeli, Paolo, Romano, Antonietta, Ludovico Rapaccini, Gian, Miele, Luca, Cima, Serena, Luisa Russo, Maria, Cozzolongo, Raffaele, Onnelli, Giovanna, D'Offizi, Giampiero, Lionetti, Raffaella, Montalbano, Marzia, Guerra, Michele, Di Perri, Giovanni, Boglione, Lucio, Capra, Franco, Carolo, Giada, Ieluzzi, Donatella, Antonini, Cinzia, Termite, Antonio, Madonia, Salvatore, Tarquini, Pierluigi, Parruti, Giustino, Vecchiet, Giacomo, Falasca, Katia, Menzaghi, Barbara, Quirino, Tiziana, Dentone, Chiara, Maria Piscaglia, Anna, Rossi, Cristina, Giordani, Maria, Fontanella, Luca, Cassola, Giovanni, Russello, Maurizio, Cristaudo, Antonio, Giacomet, Vania, Colombo, Massimo, Donato, Francesca, Durante, Emanuele, Cosco, Lucio, Marignani, Massimo, Quartini, Mariano, Memoli, Massimo, Ganga, Roberto, Ponti, Laura, Soria, Alessandro, Grazia Rumi, Maria, Gulminetti, Roberto, Maserati, Renato, Mondelli, Mario, Lazzarin, Adriano, Rita Parisi, Maria, Canovari, Benedetta, Avancini, Ivo, Pravadelli, Cecilia, Blanc, Pier, Pasquazzi, Caterina, Maria Mastroianni, Claudio, Lichtner, Myriam, Distefano, Marco, Magnani, Silvia, Paganin, Simona, Erne, Elke, Gatti, Pietro, Tundi, Paolo, Calabrese, Paolo, Gasbarrini, Antonio, Grieco, Antonio, Coppola, Nicola, Del Poggio, Paolo, Levrero, Massimo, Talliani, Gloria, Vullo, Vincenzo, Cauda, Roberto, La Monica, Silvia, Potenza, Domenico, Rizzo, Salvatore, Castelli, Francesco, Marie Pigozzi, Grazielle, Ciancio, Alessia, Romagnoli, Dante, Barchetti, Federica, Ivanovic, Jelena, Longo, Olimpia, Petraglia, Sandra, Paola Trotta, Maria, Petta, Salvatore, Marzioni, Marco, Russo, Pierluigi, Aghemo, Alessio, Alberti, Alfredo, Ascione, Antonio, Antinori, Andrea, Bruno, Raffaele, Bruno, Savino, Chirianni, Antonio, Gaeta, Giovanni Battista, Giannini, Edoardo G, Merli, Manuela, Messina, Vincenzo, Montilla, Simona, Perno, Carlo Federico, Puoti, Massimo, Raimondo, Giovanni, Rendina, Maria, Silberstein, Francesca Ceccherini, Villa, Erica, Zignego, Anna Linda, Pani, Luca, and Craxì, Antonio

Published
2017
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19. Mortality and risk factors of vaccinated and unvaccinated COVID-19 frail patients treated with anti-SARS-CoV-2 monoclonal antibodies. A real-world study

Author

Nevola, Riccardo, Feola, Giovanni, Ruocco, Rachele, Russo, Antonio, Villani, Angela, Fusco, Raffaele, De Pascalis, Stefania, Core, Micol Del, Cirigliano, Giovanna, Pisaturo, Mariantonietta, Loffredo, Giuseppe, Rinaldi, Luca, Marrone, Aldo, Starace, Mario, Sposito, Pellegrino De Lucia, Cozzolino, Domenico, Salvatore, Teresa, Lettieri, Miriam, Marfella, Raffaele, Sasso, Ferdinando Carlo, Coppola, Nicola, Adinolfi, Luigi Elio, Nevola, Riccardo, Feola, Giovanni, Ruocco, Rachele, Russo, Antonio, Villani, Angela, Fusco, Raffaele, De Pascalis, Stefania, Core, Micol Del, Cirigliano, Giovanna, Pisaturo, Mariantonietta, Loffredo, Giuseppe, Rinaldi, Luca, Marrone, Aldo, Starace, Mario, Sposito, Pellegrino De Lucia, Cozzolino, Domenico, Salvatore, Teresa, Lettieri, Miriam, Marfella, Raffaele, Sasso, Ferdinando Carlo, Coppola, Nicola, and Adinolfi, Luigi Elio

Subjects
vaccination status, COVID-19, predictors of mortality, monoclonal antibodie
Abstract

Background: There is a scarcity of data on outcomes and predictors of therapeutic failure of mAbs in frail COVID-19 patients. Methods: Prospective study including consecutive COVID-19 outpatients referred by primary care physicians for mAbs treatment. Outcomes evaluated were 60-day mortality, time to SARS-CoV-2 clearance, need for hospitalization, and O2-therapy. Results: Among 1026 COVID-19 patients enrolled, 60.2% received casirivamab/imdevimab and 39.8% sotrivimab. Median age was 63 years, 52.4% were males and median time from positive nasopharyngeal swab to mAbs administration was 3 days [IQR, 2-5]. 78.1% were vaccinated. Overall, 60-day mortality was 2.14%. No differences in outcomes were observed between the two mAbs used. No difference was observed in mortality between vaccinated and unvaccinated patients (p=0.925), although lower rate of hospitalization (p

Published
2023

21. Neoadjuvant and Adjuvant Systemic Therapies in Loco-Regional Treatments for Hepatocellular Carcinoma: Are We at the Dawn of a New Era?

Author

Nevola, Riccardo, primary, Delle Femine, Augusto Delle, additional, Rosato, Valerio, additional, Kondili, Loreta Anesti, additional, Alfano, Maria, additional, Mastrocinque, Davide, additional, Imbriani, Simona, additional, Perillo, Pasquale, additional, Beccia, Domenico, additional, Villani, Angela, additional, Ruocco, Rachele, additional, Criscuolo, Livio, additional, La Montagna, Marco La, additional, Russo, Antonio, additional, Marrone, Aldo, additional, Sasso, Ferdinando Carlo, additional, Marfella, Raffaele, additional, Rinaldi, Luca, additional, Esposito, Nicolino, additional, Barberis, Giuseppe, additional, and Claar, Ernesto, additional

Published
2023
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22. HBV Infection and Host Interactions: The Role in Viral Persistence and Oncogenesis

Author

Nevola, Riccardo, primary, Beccia, Domenico, additional, Rosato, Valerio, additional, Ruocco, Rachele, additional, Mastrocinque, Davide, additional, Villani, Angela, additional, Perillo, Pasquale, additional, Imbriani, Simona, additional, Delle Femine, Augusto, additional, Criscuolo, Livio, additional, Alfano, Maria, additional, La Montagna, Marco, additional, Russo, Antonio, additional, Marfella, Raffaele, additional, Cozzolino, Domenico, additional, Sasso, Ferdinando Carlo, additional, Rinaldi, Luca, additional, Marrone, Aldo, additional, Adinolfi, Luigi Elio, additional, and Claar, Ernesto, additional

Published
2023
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23. Trends in chronic hepatitis B virus infection in Italy over a 10-year period: Clues from the nationwide PITER and MASTER cohorts toward elimination

Author

Brancaccio, Giuseppina, primary, Coco, Barbara, additional, Nardi, Alessandra, additional, Quaranta, Maria Giovanna, additional, Tosti, Maria Elena, additional, Ferrigno, Luigina, additional, Cacciola, Irene, additional, Messina, Vincenzo, additional, Chessa, Luchino, additional, Morisco, Filomena, additional, Milella, Michele, additional, Barbaro, Francesco, additional, Ciancio, Alessia, additional, Russo, Francesco Paolo, additional, Coppola, Nicola, additional, Blanc, Pierluigi, additional, Claar, Ernesto, additional, Verucchi, Gabriella, additional, Puoti, Massimo, additional, Zignego, Anna Linda, additional, Chemello, Liliana, additional, Madonia, Salvatore, additional, Fagiuoli, Stefano, additional, Marzano, Alfredo, additional, Ferrari, Carlo, additional, Lampertico, Pietro, additional, Di Marco, Vito, additional, Craxì, Antonio, additional, Santantonio, Teresa Antonia, additional, Raimondo, Giovanni, additional, Brunetto, Maurizia R., additional, Gaeta, Giovanni Battista, additional, Kondili, Loreta A., additional, Pasulo, Luisa, additional, Coppola, Carmine, additional, Pisano, Federica, additional, Romano, Mariarosaria, additional, Porcu, Carmen, additional, Bottalico, Irene Francesca, additional, Cossiga, Valentina, additional, Tata, Xhimi, additional, Sagnelli, Caterina, additional, Pierotti, Piera, additional, Degasperi, Elisabetta, additional, Rosato, Valerio, additional, Badia, Lorenzo, additional, Ieluzzi, Dontella, additional, Monti, Monica, additional, Bavetta, Maria Grazia, additional, Cavalletto, Luisa, additional, Toniutto, Pierluigi, additional, Fornasiere, Ezio, additional, Colecchia, Antonio, additional, Ferrarese, Alberto, additional, Nardone, Gerardo, additional, Rocco, Alba, additional, Viganò, Mauro, additional, Foschi, Francesco Giuseppe, additional, Conti, Fabio, additional, Morsica, Giulia, additional, Salpietro, Stefania, additional, Torti, Carlo, additional, Costa, Chiara, additional, Federico, Alessandro, additional, Dallio, Marcello, additional, Giorgini, Alessia, additional, Anselmo, Marco, additional, De Leo, Pasqualina, additional, Zaltron, Serena, additional, Cambianica, Anna, additional, Piscaglia, Fabio, additional, Serio, Ilaria, additional, Schivazappa, Simona, additional, Mastroianni, Antonio, additional, Chidichimo, Luciana, additional, Massari, Marco, additional, Mazzaro, Cesare, additional, Marrone, Aldo, additional, D'Amore, Francesca Maria, additional, D'Offizi, Gianpiero, additional, Licata, Anna, additional, Niro, Grazia Anna, additional, Pollicino, Teresa, additional, and Aghemo, Alessio, additional

Published
2023
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24. PNPLA3 and HSD17B13 Polymorphisms’ Influence on Liver Fibrosis Development in a Small Cohort of Italian Patients With Viral Hepatitis

Author

Zampino, Rosa, primary, Coppola, Nicola, additional, Cirillo, Grazia, additional, Iossa, Domenico, additional, Starace, Mario, additional, Marrone, Aldo, additional, Vitrone, Martina, additional, De Pascalis, Stefania, additional, Macera, Margherita, additional, Improta, Marta, additional, Adinolfi, Luigi Elio, additional, Durante-Mangoni, Emanuele, additional, and Miraglia del Giudice, Emanuele, additional

Published
2023
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26. Predictors of early and late hepatocellular carcinoma recurrence

Author

Nevola, Riccardo, primary, Ruocco, Rachele, additional, Criscuolo, Livio, additional, Villani, Angela, additional, Alfano, Maria, additional, Beccia, Domenico, additional, Imbriani, Simona, additional, Claar, Ernesto, additional, Cozzolino, Domenico, additional, Sasso, Ferdinando Carlo, additional, Marrone, Aldo, additional, Adinolfi, Luigi Elio, additional, and Rinaldi, Luca, additional

Published
2023
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27. Effects of a Combination of Empagliflozin Plus Metformin vs. Metformin Monotherapy on NAFLD Progression in Type 2 Diabetes: The IMAGIN Pilot Study

Author

Caturano, Alfredo, primary, Galiero, Raffaele, additional, Loffredo, Giuseppe, additional, Vetrano, Erica, additional, Medicamento, Giulia, additional, Acierno, Carlo, additional, Rinaldi, Luca, additional, Marrone, Aldo, additional, Salvatore, Teresa, additional, Monda, Marcellino, additional, Sardu, Celestino, additional, Marfella, Raffaele, additional, and Sasso, Ferdinando Carlo, additional

Published
2023
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31. Remdesivir plus dexamethasone versus dexamethasone alone for the treatment of COVID-19 patients requiring supplemental O2 therapy: a prospective controlled non-randomized study

Author

Marrone, Aldo, Nevola, Riccardo, Sellitto, Ausilia, Cozzolino, Domenico, Romano, Ciro, Cuomo, Giovanna, Aprea, Concetta, Schwartzbaum, Michelangelo X Palou, Ricozzi, Carmen, Imbriani, Simona, Rinaldi, Luca, Gjeloshi, Klodian, Padula, Andrea, Ranieri, Roberta, Ruosi, Carolina, Meo, Luciana Agnese, Abitabile, Marianna, Cinone, Francesca, Carusone, Caterina, Adinolfi, Luigi Elio, Marrone, Aldo, Nevola, Riccardo, Sellitto, Ausilia, Cozzolino, Domenico, Romano, Ciro, Cuomo, Giovanna, Aprea, Concetta, Schwartzbaum, Michelangelo X Palou, Ricozzi, Carmen, Imbriani, Simona, Rinaldi, Luca, Gjeloshi, Klodian, Padula, Andrea, Ranieri, Roberta, Ruosi, Carolina, Meo, Luciana Agnese, Abitabile, Marianna, Cinone, Francesca, Carusone, Caterina, and Adinolfi, Luigi Elio

Subjects
Dexamethasone. Survival, Remdesivir, COVID-19, viral clearance
Abstract

Background: Remdesivir is an antiviral used to treat COVID-19 which improves some clinical outcomes. Dexamethasone has been shown to be effective in reducing mortality. It has been hypothesized that combination of these two drugs can improve mortality. We evaluated the effect of combination on mortality of COVID-19 patients requiring O2 therapy. Methods: A prospective quasi-experimental study, including two independent, sequential controlled cohorts, one received remdesivir-dexamethasone and the other dexamethasone alone, was designed. All COVID-19 patients requiring supplemental O2 therapy were enrolled consecutively. The sample size to power mortality was a priori calculated. The primary endpoints were 30-day mortality and viral clearance differences. Secondary endpoints were differences in hospitalization times, improvement in respiratory failure (PO2/FiO2) and inflammatory indices (fibrinogen, CRP, neutrophil/lymphocyte ratio, D-Dimer). Kaplan-Meier curves and the log-rank test were used to evaluate significant differences in mortality between groups. Results: 151 COVID-19 patients were enrolled (remdesivir/dexamethasone group, 76 and dexamethasone alone,75). No differences in demographic, clinical and laboratory characteristics were observed between the two groups at baseline. Faster viral clearance occurred in the remdesivir/dexamethasone group compared to dexamethasone alone (median 6 vs 16 days; p

Published
2022

33. Elbasvir/Grazoprevir combination therapy in a B-NHL patient with HCV genotype 1 infection

Author

Sica, Antonello, Spada, Alessandro, Sagnelli, Caterina, Verolino, Pasquale, Mazzocca, Annalisa, Sagnelli, Evangelista, Colella, Giuseppe, Guastafierro, Salvatore, Marrone, Aldo, Sica, Antonello, Spada, Alessandro, Sagnelli, Caterina, Verolino, Pasquale, Mazzocca, Annalisa, Sagnelli, Evangelista, Colella, Giuseppe, Guastafierro, Salvatore, and Marrone, Aldo

Subjects
Antiviral Agent, Genotype, Sustained Virologic Response, Lymphoma, Non-Hodgkin, Imidazoles, Hepatitis C, Chronic, Middle Aged, Antiviral Agents, hemic and lymphatic diseases, Humans, Female, Benzofuran, Imidazole, Human, Benzofurans
Abstract

Patients with indolent non-Hodgkin lymphomas (NHL) may often be followed up only with observation, reserving chemotherapy in case of spread. Patients with chronic HCV infection and B cell NHL frequently undergo regression of lymphoproliferative disease once HCV infection is eradicated by treatment. Interferon (IFN)-based therapy has been the treatment of choice for years, remaining unclear whether it is effective in B cell NHL directly or through HCV eradication, since IFN is effective in both HCV infection and B cell NHL. IFN therapy for HCV infection became obsolete with the advent of the well tolerated direct-acting antiviral agents (DAAs), whose excellent efficacy in treating patients with chronic HCV infection and B cell NHL has been recently highlighted. We treated a 53-year-old woman with chronic HCV infection and marginal zone lymphoma (MZL) with elbasvir plus grazoprevir in 2018, with complete remission and persisting excellent results: sustained virological response 24 weeks after treatment (SVR24). The exclusive role of HCV eradication in B cell NHL regression is also underlined.

Published
2021

34. A Case Report on Treatment of Nonhealing Leg Ulcer: Do Not Forget the Underlying Disease.

Author

Sallustro, Marianna, Marrone, Aldo, and Florio, Anna

Abstract

Prevalence of nonhealing ulcers of lower extremities has increased over years causing heavy health, social, and economic burdens. Chronic ulcers are difficult to treat since they require tailored multistep treatment and patient compliance. To treat chronic wounds successfully, clinicians must keep in mind the ulcer etiology as well as the underlying diseases. Several factors may be involved in the pathogenesis of chronic skin ulcers. Leukocytoclastic vasculitis belongs to the group of immune vascular diseases and may be an extrahepatic manifestation of hepatitis C virus (HCV) infection. We describe the case of a patient with a nonhealing vasculitic leg ulcer and chronic HCV infection successfully treated with the combination of advanced dermal substitute and direct-acting antiviral therapy. An 81-year-old female presented to our unit with a 6-month history of a leg ulcer that developed from an exudating skin nodule. At presentation, the lesion was large,caused a severe pain and was unresponsive to analgesics. Skin biopsy showed leukocytoclastic vasculitis. She had a history of old untreated HCV infection, hypertension, type 2 diabetes mellitus, chronic venous insufficiency and tibial arteriopathy. The application of porcine-derived dermal substitute achieved only initial improvement. Therefore, direct-acting antiviral therapy was started, and when HCV RNA became undetectable in blood, pain disappeared and skin ulcer improved up to healing. In conclusion vasculitic leg ulcers can be caused by HCV infection. In such cases, even the use of innovative skin therapy, may obtain only initial and partial improvement, and eradication of HCV viremiais essential to obtain wound healing. [ABSTRACT FROM AUTHOR]

Published
2023
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37. Prediction of SARS-CoV-2-Related Lung Inflammation Spreading by V:ERITAS (Vanvitelli Early Recognition of Inflamed Thoracic Areas Spreading)

Author

Romano, Ciro, primary, Cozzolino, Domenico, additional, Cuomo, Giovanna, additional, Abitabile, Marianna, additional, Carusone, Caterina, additional, Cinone, Francesca, additional, Nappo, Francesco, additional, Nevola, Riccardo, additional, Sellitto, Ausilia, additional, Auricchio, Annamaria, additional, Cardella, Francesca, additional, Del Sorbo, Giovanni, additional, Lieto, Eva, additional, Galizia, Gennaro, additional, Adinolfi, Luigi Elio, additional, Marrone, Aldo, additional, and Rinaldi, Luca, additional

Published
2022
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38. Epidemiology of HCV and HBV in a High Endemic Area of Southern Italy: Opportunities from the COVID-19 Pandemic—Standardized National Screening or One Tailored to Local Epidemiology?

Author

Nevola, Riccardo, primary, Messina, Vincenzo, additional, Marrone, Aldo, additional, Coppola, Nicola, additional, Rescigno, Carolina, additional, Esposito, Vincenzo, additional, Sangiovanni, Vincenzo, additional, Claar, Ernesto, additional, Pisaturo, Mariantonietta, additional, Fusco, Francesco Maria, additional, Rosario, Pietro, additional, Izzi, Antonio, additional, Pisapia, Raffaella, additional, Rosato, Valerio, additional, Maggi, Paolo, additional, and Adinolfi, Luigi Elio, additional

Published
2022
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40. Remdesivir Plus Dexamethasone Versus Dexamethasone Alone for the Treatment of Coronavirus Disease 2019 (COVID-19) Patients Requiring Supplemental O2 Therapy: A Prospective Controlled Nonrandomized Study

Author

Marrone, Aldo, primary, Nevola, Riccardo, additional, Sellitto, Ausilia, additional, Cozzolino, Domenico, additional, Romano, Ciro, additional, Cuomo, Giovanna, additional, Aprea, Concetta, additional, Schwartzbaum, Michelangelo X Palou, additional, Ricozzi, Carmen, additional, Imbriani, Simona, additional, Rinaldi, Luca, additional, Gjeloshi, Klodian, additional, Padula, Andrea, additional, Ranieri, Roberta, additional, Ruosi, Carolina, additional, Meo, Luciana Agnese, additional, Abitabile, Marianna, additional, Cinone, Francesca, additional, Carusone, Caterina, additional, and Adinolfi, Luigi Elio, additional

Published
2022
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41. Authors’ response

Author

Romano, Ciro, primary, Esposito, Sergio, additional, Donnarumma, Giovanna, additional, and Marrone, Aldo, additional

Published
2021
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44. Factors affecting long‐term changes of liver stiffness in direct‐acting anti‐hepatitis C virus therapy: A multicentre prospective study

Author

Rosato, Valerio, primary, Ascione, Antonio, additional, Nevola, Riccardo, additional, Fracanzani, Anna Ludovica, additional, Piai, Guido, additional, Messina, Vincenzo, additional, Claar, Ernesto, additional, Coppola, Carmine, additional, Fontanella, Luca, additional, Lombardi, Rosa, additional, Staiano, Laura, additional, Valente, Giovanna, additional, Fascione, Maria Chiara, additional, Giorgione, Chiara, additional, Mazzocca, Annalisa, additional, Galiero, Raffaele, additional, Perillo, Pasquale, additional, Marrone, Aldo, additional, Sasso, Ferdinando Carlo, additional, Adinolfi, Luigi Elio, additional, and Rinaldi, Luca, additional

Published
2021
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46. Hepatitis B surface antigen genetic elements critical for immune escape correlate with hepatitis B virus reactivation upon immunosuppression

Author

Salpini, Romina, Colagrossi, Luna, Bellocchi, Maria Concetta, Surdo, Matteo, Becker, Christina, Alteri, Claudia, Aragri, Marianna, Ricciardi, Alessandra, Armenia, Daniele, Pollicita, Michela, Di Santo, Fabiola, Carioti, Luca, Louzoun, Yoram, Mastroianni, Claudio Maria, Lichtner, Miriam, Paoloni, Maurizio, Esposito, Mariarosaria, DʼAmore, Chiara, Marrone, Aldo, Marignani, Massimo, Sarrecchia, Cesare, Sarmati, Loredana, Andreoni, Massimo, Angelico, Mario, Verheyen, Jens, Perno, Carlo-Federico, and Svicher, Valentina

Published
2015
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48. Impact of hepatitis C virus clearance by direct-acting antiviral treatment on the incidence of major cardiovascular events: A prospective multicentre study

Author

Adinolfi, Luigi Elio, Petta, Salvatore, Fracanzani, Anna Ludovica, Coppola, Carmine, Narciso, Vincenzo, Nevola, Riccardo, Rinaldi, Luca, Calvaruso, Vincenza, Staiano, Laura, Di Marco, Vito, Marrone, Aldo, Pafundi, Pia Clara, Solano, Antonio, Lombardi, Rosa, Sasso, Ferdinando Carlo, Saturnino, Mariarosaria, Rini, Francesca, Guerrera, Barbara, Troina, Graziano, Giordano, Mauro, and Craxì, Antonio

Published
2020
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