9 results on '"Marouene S"'
Search Results
2. Facteurs de risque de complications digestives des patients sous antiagrégant plaquettaire suivis en cardiologie de ville : description et prise en charge
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Marc-André Bigard, Caroline Fabry, investigateurs Caap, Philippe Barthélémy, Philippe Gabriel Steg, Marouene S, Pierre-Henri Delaage, and Gregory Ducrocq
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Gynecology ,medicine.medical_specialty ,Multicenter study ,business.industry ,Private practice ,Treatment outcome ,Medicine ,Cardiology and Cardiovascular Medicine ,business - Abstract
Resume But de l’etude Les patients sous antiagregants plaquettaires presentent un risque de saignement digestif qui est accru en presence de facteurs de risque. La frequence de ces facteurs de risque, la prevalence des symptomes digestifs et leur prise en charge chez les patients sous antiagregants plaquettaires restent toutefois mal connus. Patients et methodes Il s’agit d’une enquete observationnelle multicentrique prospective realisee aupres d’un echantillon de 560 cardiologues liberaux francais. Chaque medecin a complete un questionnaire pour les quatre premiers patients consecutifs traites par antiagregant plaquettaire en vue de prevention cardiovasculaire primaire ou secondaire. Resultats Parmi les 2182 patients inclus (âge = 67 ± 11 ans, hommes = 74 %), 83 % avaient au moins un facteur de risque de complication hemorragique, 38,9 % au moins un antecedent de symptome digestif, 3,4 % un antecedent de saignement digestif et 5,5 % un antecedent d’ulcere documente. Un inhibiteur de la pompe a protons etait prescrit chez 39 % des patients avant la consultation. Au moment de la consultation, des signes digestifs hauts etaient retrouves chez 21 % des patients. Parmi cette population, la prise en charge ne se traduisait par aucune modification du traitement antiagregant plaquettaire dans 85 % des cas et un protecteur gastrique etait prescrit dans 62,7 % des cas (Inhibiteurs de la pompe a protons : 51,8 % ; anti-H2 : 3,6 % ; autres anti-acides : 7,3 %). Conclusion Parmi les patients sous antiagregants plaquettaires, la prevalence des signes digestifs hauts et des facteurs de risque de complication digestive est elevee. Les mesures de prevention meritent d’etre clarifiees dans cette population.
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- 2012
3. Prevención secundaria en el paciente coronario
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Steg, P.-G., primary and Marouene, S., additional
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- 2013
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4. Prévention secondaire chez le coronarien
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Steg, P.-G., primary and Marouene, S., additional
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- 2012
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5. [Clinical characteristics, management and prognostic evolution of patients admitted within six hours of symptom onset with st-segment elevation acute myocardial infarction complicated by cardiogenic shock : twenty year monocentric study]
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Marouene S, Jm, Juliard, Jl, Golmard, Aubry P, Gregory Ducrocq, Feldman L, Pg, Steg, and Vahanian A
6. Design and Rationale of the National Tunisian Registry of Percutaneous Coronary Intervention: Protocol for a Prospective Multicenter Observational Study.
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Hammami R, Boudiche S, Rami T, Ben Halima N, Jamel A, Rekik B, Gribaa R, Imtinene BM, Charfeddine S, Ellouze T, Bahloul A, Hédi BS, Langar J, Ben Ahmed H, Ibn Elhadj Z, Hmam M, Ben Abdessalem MA, Maaoui S, Fennira S, Lobna L, Hassine M, Ouanes S, Mohamed Faouzi D, Mallek S, Mahdhaoui A, Meriem D, Jomaa W, Zayed S, Kateb T, Bouchahda N, Azaiez F, Ben Salem H, Marouen M, Noamen A, Abdesselem S, Hichem D, Ibn Hadj Amor H, Abdeljelil F, Amara A, Bejar K, Khaldoun BH, Hamza C, Ben Jamaa M, Fourati S, Elleuch F, Grati Z, Chtourou S, Marouene S, Sahnoun M, Hadrich M, Mohamed Abdelkader M, Bouraoui H, Kamoun K, Hadrich M, Ben Chedli T, Drissa MA, Charfeddine H, Saadaoui N, Achraf G, Ahmed S, Ayari M, Nabil M, Mnif S, Sahnoun M, Kammoun H, Ben Jemaa K, Mostari G, Hamrouni N, Yamen M, Ellouz Y, Smiri Z, Hdiji A, Bassem J, Ayadi W, Zouari A, Abbassi C, Fatma BM, Battikh K, Kharrat E, Gtif I, Sami M, Bezdah L, Kachboura S, Maatouk MF, Kraiem S, Jeridi G, Neffati E, Kammoun S, Ben Ameur Y, Fehri W, Gamra H, Zakhama L, Addad F, Mohamed Sami M, and Abid L
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Background: Coronary artery diseases remain the leading cause of death in the world. The management of this condition has improved remarkably in the recent years owing to the development of new technical tools and multicentric registries., Objective: The aim of this study is to investigate the in-hospital and 1-year clinical outcomes of patients treated with percutaneous coronary intervention (PCI) in Tunisia., Methods: We will conduct a prospective multicentric observational study with patients older than 18 years who underwent PCI between January 31, 2020 and June 30, 2020. The primary end point is the occurrence of a major adverse cardiovascular event, defined as cardiovascular death, myocardial infarction, cerebrovascular accident, or target vessel revascularization with either repeat PCI or coronary artery bypass grafting (CABG). The secondary end points are procedural success rate, stent thrombosis, and the rate of redo PCI/CABG for in-stent restenosis., Results: In this study, the demographic profile and the general risk profile of Tunisian patients who underwent PCI and their end points will be analyzed. The complexity level of the procedures and the left main occlusion, bifurcation occlusion, and chronic total occlusion PCI will be analyzed, and immediate as well as long-term results will be determined. The National Tunisian Registry of PCI (NATURE-PCI) will be the first national multicentric registry of angioplasty in Africa. For this study, the institutional ethical committee approval was obtained (0223/2020). This trial consists of 97 cardiologists and 2498 patients who have undergone PCI with a 1-year follow-up period. Twenty-eight catheterization laboratories from both public (15 laboratories) and private (13 laboratories) sectors will enroll patients after receiving informed consent. Of the 2498 patients, 1897 (75.9%) are managed in the public sector and 601 (24.1%) are managed in the private sector. The COVID-19 pandemic started in Tunisia in March 2020; 719 patients (31.9%) were included before the COVID-19 pandemic and 1779 (60.1%) during the pandemic. The inclusion of patients has been finished, and we expect to publish the results by the end of 2022., Conclusions: This study would add data and provide a valuable opportunity for real-world clinical epidemiology and practice in the field of interventional cardiology in Tunisia with insights into the uptake of PCI in this limited-income region., Trial Registration: Clinicaltrials.gov NCT04219761; https://clinicaltrials.gov/ct2/show/NCT04219761., International Registered Report Identifier (irrid): RR1-10.2196/24595., (©Rania Hammami, Selim Boudiche, Tlili Rami, Nejeh Ben Halima, Ahmed Jamel, Bassem Rekik, Rym Gribaa, Ben Mrad Imtinene, Salma Charfeddine, Tarek Ellouze, Amine Bahloul, Ben Slima Hédi, Jamel Langar, Habib Ben Ahmed, Zied Ibn Elhadj, Mohamed Hmam, Mohamed Aymen Ben Abdessalem, Sabri Maaoui, Sana Fennira, Laroussi Lobna, Majed Hassine, Sami Ouanes, Drissi Mohamed Faouzi, Souad Mallek, Abdallah Mahdhaoui, Dghim Meriem, Walid Jomaa, Sofien Zayed, Tawfik Kateb, Nidhal Bouchahda, Fares Azaiez, Helmi Ben Salem, Morched Marouen, Aymen Noamen, Salem Abdesselem, Denguir Hichem, Hassen Ibn Hadj Amor, Farhati Abdeljelil, Amine Amara, Karim Bejar, Ben Hamda Khaldoun, Chiheb Hamza, Mohsen Ben Jamaa, Sami Fourati, Faycal Elleuch, Zeineb Grati, Slim Chtourou, Sami Marouene, Mohamed Sahnoun, Morched Hadrich, Maalej Mohamed Abdelkader, Hatem Bouraoui, Kamel Kamoun, Moufid Hadrich, Tarek Ben Chedli, Mohamed Akrem Drissa, Hanene Charfeddine, Nizar Saadaoui, Gargouri Achraf, Siala Ahmed, Mokdad Ayari, Marsit Nabil, Sabeur Mnif, Maher Sahnoun, Helmi Kammoun, Khaled Ben Jemaa, Gharbi Mostari, Nebil Hamrouni, Maazoun Yamen, Yassine Ellouz, Zahreddine Smiri, Amine Hdiji, Jerbi Bassem, Wacef Ayadi, Amir Zouari, Chedly Abbassi, Boujelben Masmoudi Fatma, Kais Battikh, Elyes Kharrat, Imen Gtif, Milouchi Sami, Leila Bezdah, Salem Kachboura, Mohamed Faouzi Maatouk, Sondes Kraiem, Gouider Jeridi, Elyes Neffati, Samir Kammoun, Youssef Ben Ameur, Wafa Fehri, Habib Gamra, Lilia Zakhama, Faouzi Addad, Mourali Mohamed Sami, Leila Abid. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 05.08.2022.)
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- 2022
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7. [Clinical characteristics, management and prognostic evolution of patients admitted within six hours of symptom onset with st-segment elevation acute myocardial infarction complicated by cardiogenic shock : twenty year monocentric study].
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Marouene S, Juliard JM, Golmard JL, Aubry P, Ducrocq G, Feldman L, Steg PG, and Vahanian A
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- Aged, Cohort Studies, Emergency Medical Services, Female, Fibrinolytic Agents therapeutic use, Follow-Up Studies, France, Humans, Male, Middle Aged, Percutaneous Coronary Intervention statistics & numerical data, Prognosis, Time-to-Treatment, Myocardial Infarction mortality, Myocardial Infarction therapy, Shock, Cardiogenic mortality, Shock, Cardiogenic therapy
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Background: Cardiogenic shock is one of the most serious complications of the acute myocardial infarction. Advances in interventional cardiology and early reperfusion strategy improved its management., Aim: Analysis of the clinical characteristics, management and prognostic evolution of patients admitted within 6 hours onset with ST-segment elevation acute myocardial infarction complicated by cardiogenic shock., Methods: Follow-up study based on 2200 consecutive patients admitted with STEMI within 6 hours of symptom onset from 1988 to 2008. Among them 114 matched the criteria of cardiogenic shock. These were divided in two groups, according to the period: group 1 (N=57, among the first 1100 STEMI from 1988 to 1998) and group 2 (N=57, among the following 1100 STEMI from 1999 to 2008)., Results: This trial shows a similar rate of cardiogenic shock in STEMI (5%) in both 1100 patients groups. There is no overall change in patient's clinical characteristics, but improvements in earlier management, prehospital fibrinolysis and ventricular fibrillation treatment have been detected. Primary percutaneous coronary intervention was the most common revascularisation strategy. The proportion of patients achieving acute TIMI-3 flow in the infarct related artery increased (61% vs 80%, p= 0.11) but the mortality was still high (74% vs 63%, p= 0.22)., Conclusion: The clinical characteristics of cardiogenic shock remain unchanged; its management is more successful with more often early reperfusion. The decline of mortality is unfortunately not significant. More aggressive treatment should probably be considered to improve outcomes.
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- 2012
8. [Risk factors of upper gastrointestinal complications in outpatients on antiplatelet therapy: description and management].
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Ducrocq G, Bigard MA, Marouene S, Delaage PH, Fabry C, Barthelemy P, and Steg PG
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- Aged, Anti-Ulcer Agents therapeutic use, Cardiology, Cardiovascular Diseases prevention & control, Drug Therapy, Combination, Female, France epidemiology, Gastrointestinal Hemorrhage chemically induced, Gastrointestinal Hemorrhage prevention & control, Health Care Surveys, Histamine H2 Antagonists therapeutic use, Humans, Male, Middle Aged, Peptic Ulcer Hemorrhage epidemiology, Platelet Aggregation Inhibitors administration & dosage, Prevalence, Private Practice, Prospective Studies, Proton Pump Inhibitors therapeutic use, Risk Factors, Stomach Ulcer epidemiology, Surveys and Questionnaires, Treatment Outcome, Upper Gastrointestinal Tract drug effects, Gastrointestinal Agents therapeutic use, Outpatients statistics & numerical data, Peptic Ulcer Hemorrhage chemically induced, Peptic Ulcer Hemorrhage prevention & control, Physicians statistics & numerical data, Platelet Aggregation Inhibitors adverse effects, Stomach Ulcer chemically induced, Stomach Ulcer prevention & control
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Objectives: Patients on antiplatelet therapy have a gastrointestinal bleeding risk. It is increased by risk factors. The frequency of those risk factors, the prevalence of upper digestive symptoms and their management in patients on antiplatelet agents is unknown., Patients and Methods: We performed an observational multi-centred prospective survey among 560 French cardiologists with private practice. Each cardiologist completed a questionnaire for the first four patients treated with antiplatelet agents in primary or secondary prevention., Results: Among the 2182 patients included, (age = 67 ± 11 years; 74% male), 83% had at least one gastrointestinal bleeding risk factor and 38.9% had a history of upper digestive tract symptom. A history of gastrointestinal bleeding was reported in 3.4% and a history of documented gastro-duodenal ulcer in 5.5%. A proton pump inhibitor was already prescribed in 39% of the patients. At the time of the consultation, upper digestive symptoms were described in 21% of the patients. In those patients with symptoms, 85% had no modification in antiplatelet therapy and 62.7% were prescribed gastro-protective drugs (proton pump inhibitors: 51.8%, H(2)-blockers 3.6% other anti-acid medication: 7.3%)., Conclusion: Among patients on antiplatelet agents, the prevalence of upper digestive symptoms and risk factors for gastrointestinal bleeding is high. Preventative management needs to be clarified in this population., (Copyright © 2012 Elsevier Masson SAS. All rights reserved.)
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- 2012
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9. Vascular complications of transfemoral aortic valve implantation with the Edwards SAPIEN prosthesis: incidence and impact on outcome.
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Ducrocq G, Francis F, Serfaty JM, Himbert D, Maury JM, Pasi N, Marouene S, Provenchère S, Iung B, Castier Y, Lesèche G, and Vahanian A
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- Aged, Aged, 80 and over, Angiography, Aortic Valve Stenosis diagnosis, Catheterization, Peripheral methods, Female, Femoral Artery, Follow-Up Studies, Heart Valve Prosthesis Implantation methods, Hospital Mortality trends, Humans, Incidence, Length of Stay, Male, Netherlands epidemiology, Postoperative Complications, Prospective Studies, Prosthesis Design, Treatment Outcome, Ultrasonography, Doppler, Color, Vascular Diseases etiology, Aortic Valve Stenosis surgery, Catheterization, Peripheral adverse effects, Heart Valve Prosthesis, Heart Valve Prosthesis Implantation adverse effects, Vascular Diseases epidemiology
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Aims: Vascular complications remain the main limitation of transfemoral aortic valve implantation. Based on a single-centre experience, we aim to detail the type, management and impact of those vascular complications., Methods and Results: From October 2006 to January 2009, 54 transfemoral aortic valve implantations were performed using the Edwards SAPIEN prosthesis. Nine patients (16.7%) developed vascular complications. Five patients (9.3%) had ruptures which necessitated a surgical bypass. Four patients (7.4%) had dissection necessitating repair using stenting in all four patients and associated bypass in two of them. Vascular complications led to death in one patient (1.9%), reintervention in one (1.9%), and transfusions in seven (13%). Five vascular complications occurred in the first 20 patients (25%), and only four in the last 34 (12%)., Conclusions: Vascular complications of transfemoral aortic valve implantation are frequent and seem to be influenced by experience. They are associated with a high need for transfusion and could lead to major events such as death or reintervention. These findings highlight the importance of a multidisciplinary approach for patient selection and management of the procedure.
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- 2010
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