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2. Novel biomarkers predict ablation outcomes in long stranding persistent atrial fibrillation

Author

Boyalla, V, primary, Bodinier, B, additional, Kralj-Hans, I, additional, Haldar, S, additional, Khan, HR, additional, Shi, R, additional, Cantor, E, additional, Hussain, W, additional, Jones, DG, additional, Jarman, JWE, additional, Markides, V, additional, Chadeau-Hyam, M, additional, Harding, SE, additional, Cleland, JGF, additional, and Wong, T, additional

Published
2022
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8. Journal scan

Author

Baker, C, Barnes, E, Bhatia, V, Desilva, R, Earley, M, Fox, K, Gorog, D, Jenkins, G, Kaprilian, R, Kapur, A, Khan, M, Lambiese, P, Markides, V, Poullis, M, Ramrakha, P, Strange, J, Wasan, B, and Walker, H

Published
2001

10. P2831Safety of atrial fibrillation catheter ablation in the elderly

Author

Karim, N, primary, Marinelli, A, additional, Cantor, E, additional, Boyalla, V, additional, Malaczynska-Rajpold, K, additional, Ahmed, O, additional, Khan, H, additional, Haldar, S, additional, Jones, D, additional, Hussein, W, additional, Markides, V, additional, Wong, T, additional, and Jarman, J, additional

Published
2019
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12. P3756Diverse activation patterns during persistent atrial fibrillation characterised by dipole density non-contact mapping

Author

Shi, R, primary, Chen, Z, additional, Butcher, C, additional, Zaman, Z, additional, Boyalla, V, additional, Wang, Y K, additional, Riad, O, additional, Sathishkumar, A, additional, Norman, M, additional, Haldar, S, additional, Jones, D G, additional, Hussain, W, additional, Markides, V, additional, and Wong, T, additional

Published
2019
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16. Titin Truncating Variants Predict Life-threatening Arrhythmias in Patients With Dilated Cardiomyopathy

Author

Corden, B, Jarman, J, Whiffin, N, Tayal, U, Buchan, R, Sehmi, J, Harper, A, Midwinter, W, Lascelles, K, Markides, V, Mason, M, Pennell, DJ, Barton, PJ, Prasad, SK, Wong, T, Cook, SA, Ware, JS, and Wellcome Trust

Subjects
Science & Technology, Cardiac & Cardiovascular Systems, Cardiomyopathy, adult, Heart failure, Ventricular tachycardia, 1103 Clinical Sciences, Hematology, 1102 Cardiovascular Medicine And Haematology, Peripheral Vascular Disease, Cardiovascular System & Hematology, cardiovascular system, Cardiovascular System & Cardiology, Genetics, Ventricular arrhythmia, cardiovascular diseases, Life Sciences & Biomedicine
Abstract

Introduction: There is an urgent need for better arrhythmic risk stratification in non-ischaemic dilated cardiomyopathy (DCM), where the benefit of ICD implantation is unclear. Titin truncating variants (TTNtv) are the commonest genetic cause of DCM and are associated with early onset non-sustained ventricular tachycardia (NSVT) and atrial fibrillation (AF) in these patients. Hypothesis: We hypothesize that TTNtv status can predict potentially life threatening ventricular tachycardia (VT) or fibrillation (VF) and development of new persistent AF in DCM patients with CRT-D or ICD devices. Methods: We studied 117 DCM patients with an ICD or CRT-D and documented device-recorded arrhythmia over a median period of 4.2 years. Patients were stratified by TTN genotype (28 positive for a TTNtv, 89 negative). The primary outcome was time to first device-treated VT >200bpm or VF. Secondary outcome measures included time to first development of persistent AF. Results: TTNtv predicted the risk of receiving an appropriate ICD therapy for VT/VF (hazard ratio [HR] = 4.9, 95% confidence interval [CI]=2.3-10.7, P

Published
2017

17. Hypertension. (Journal Scan)

Author

Baker, C., Barnes, E., Bhatia, V., Desilva, R., Earley, M., Fox, K., Gorog, D., Jenkins, G., Kaprilian, R., Kapur, A., Khan, M., Lambiese, P., Markides, V., Poullis, M., Ramrakha, P., Strange, J., Wasan, B., and Walker, H.

Subjects
Hypertension -- Research, Health, Research
Abstract

HOPE for stroke reduction * Reduction in blood pressure in the HOPE trial with ramipril 10 mg/day was modest (3.8 mm Hg systolic and 2.8 mm Hg diastolic). The relative [...]

Published
2002

18. Biomarkers in persistent AF and heart failure: impact of catheter ablation compared with rate control

Author

Jones, DG, Haldar, SK, Donovan, J, Mcdonagh, TA, Sharma, R, Hussain, W, Markides, V, and Wong, T

Subjects
Technology, Science & Technology, Cardiac & Cardiovascular Systems, PLASMA, INTERLEUKIN-6, biomarkers, heart failure, TRANSLATIONAL LEVELS, ENDOGENOUS INOTROPE APELIN, 1103 Clinical Sciences, PROATRIAL, PROGNOSTIC VALUE, CHRONIC ATRIAL-FIBRILLATION, Engineering, Cardiovascular System & Hematology, 0903 Biomedical Engineering, BRAIN NATRIURETIC PEPTIDE, catheter ablation, Cardiovascular System & Cardiology, atrial fibrillation, Life Sciences & Biomedicine, Engineering, Biomedical, SERIAL MEASUREMENTS, rate control, INFLAMMATORY CYTOKINES
Abstract

Background To investigate the effects of catheter ablation and rate control strategies on cardiac and inflammatory biomarkers in patients with heart failure and persistent atrial fibrillation (AF). Methods Patients were recruited from the ARC-HF trial (catheter Ablation vs Rate Control for management of persistent AF in Heart Failure, NCT00878384), which compared ablation with rate control for persistent AF in heart failure. B-type natriuretic peptide (BNP), midregional proatrial natriuretic peptide (MR-proANP), apelin, and interleukin-6 (IL-6) were assayed at baseline, 3 months, 6 months, and 12 months. The primary end point, analyzed per-protocol, was changed from baseline at 12 months. Results Of 52 recruited patients, 24 ablation and 25 rate control subjects were followed to 12 months. After 1.2 ± 0.5 procedures, sinus rhythm was present in 22 (92%) ablation patients; under rate control, rate criteria were achieved in 23 (96%) of 24 patients remaining in AF. At 12 months, MR-proANP fell significantly in the ablation arm (–106.0 pmol/L, interquartile range [IQR] –228.2 to –60.6) compared with rate control (–28.7 pmol/L, IQR –69 to +9.5, P = 0.028). BNP showed a similar trend toward reduction (P = 0.051), with no significant difference in apelin (P = 0.13) or IL-6 (P = 0.68). Changes in MR-proANP and BNP correlated with peak VO2 and ejection fraction, and MR-proANP additionally with quality-of-life score. Conclusions Catheter ablation, compared with rate control, in patients with heart failure and persistent AF was associated with significant reduction in MR-proANP, which correlated with physiological and symptomatic improvement. Ablation-based rhythm control may induce beneficial cardiac remodeling, unrelated to changes in inflammatory state. This may have prognostic implications, which require confirmation by event end point studies.

Published
2016

19. 72Heart rate variability evaluation in patients with long standing persistent atrial fibrillation treated with thoracoscopic surgical ablation with ganglionic plexi ablation or catheter ablation - recordings from implantable loop recorder

Author

Khan, H, primary, Hnatkova, H, additional, Kralj-Hans, i, additional, Haldar, S, additional, Jones, DG, additional, Hussain, W, additional, Jarman, J, additional, Cowie, M, additional, Markides, V, additional, Malik, M, additional, and Wong, T, additional

Published
2017
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21. P5244Left atrial appendage exclusion as treatment strategy of ablation in longstanding persistent atrial fibrillation does not adversely affect the left atrial function in human

Author

Khan, H., primary, Di Salvo, G., additional, Kralj-Hans, I., additional, Sivalinganathan, M., additional, Hamid, S., additional, Butcher, C., additional, Haldar, S., additional, Panniker, S., additional, Jones, D., additional, Hussain, W., additional, Bahrami, T., additional, De Souza, T., additional, Markides, V., additional, Cowie, M., additional, and Wong, T., additional

Published
2017
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23. P1464Acute and medium-term outcomes following ablation of complex scar-related atrial tachycardia using a high-resolution mapping system

Author

Shi, R., primary, Viswanathan, K., additional, Mantziari, L., additional, Butcher, C., additional, Lim, E., additional, Khan, H., additional, Panikker, S., additional, Hussain, W., additional, Haldar, S., additional, Jones, D., additional, Ernst, S., additional, Foran, J., additional, Markides, V., additional, and Wong, T., additional

Published
2017
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24. Utility of a novel rapid high-resolution mapping system in the catheter ablation of arrhythmias: an initial human experience of mapping the atria and the left ventricle

Author

Mantziari, L, Butcher, C, Kontogeorgis, A, Panikker, S, Roy, K, Markides, V, and Wong, T

Subjects
cardiovascular system, atrial fibrillation, cardiovascular diseases, ventricular tachycardia, atrial tachycardia, electroanatomical mapping system, high-resolution mapping
Abstract

OBJECTIVES: This study sought to assess the clinical efficacy, safety, and clinical utility of a novel electroanatomical mapping system. BACKGROUND: A new mapping system capable of rapidly acquiring detailed maps based on automatic annotation of thousands of points was recently released for clinical use. This is the first description of its utility in humans. METHODS: The first consecutive 20 cases (7 atrial tachycardia, 8 atrial fibrillation, 3 ventricular tachycardia, and 2 ventricular ectopic beat ablations) were analyzed. The system uses a bidirectional deflectable basket catheter with 64 closely spaced mini-electrodes. It automatically accepts and annotates electrograms when a number of predefined criteria are met. RESULTS: Thirty right atrial maps were acquired in 11 (4 to 15) min, consisting of 7,220 (3,467 to 10,947) points, 22 left atrial maps in 11 (6 to 19) min, consisting of 7,818 (4,379 to 12,262) points and 10 left ventricular maps in 37 (14 to 43) min, consisting of 8,709 (2,605 to 15,514) points. The mini-basket catheter could reach all areas of interest without deflectable sheaths. No embolic events, bleeding complications, or endocardial structure damage were observed. Correction of the automatic annotation was performed in 0.02% of points in 4 of 62 maps. The system revealed re-entry circuits of atrial tachyarrhythmias, identified gaps on linear lesions, and identified and correctly annotated the clinical ventricular ectopic beats and channels of slow conduction within ventricular scar. CONCLUSIONS: The novel automatic mapping system was rapid, safe, and efficacious in mapping a variety of cardiac arrhythmias in humans. Further clinical research is needed to optimize its use in the ablation of complex arrhythmias.

Published
2015

26. ORAL ABSTRACTS (2)EP & Ablation19CARDIAC ABLATION PATIENT REPORTED OUTCOMES MEASURES (PROMS): ANALYSIS OF POST-ABLATION AND 1 YEAR FOLLOW-UP DATA20INTENTIONAL CORONARY VEIN EXIT AND CARBON DIOXIDE INSUFFLATION TO ALLOW SAFE SUBXIPHOID EPICARDIAL ACCESS FOR VENTRICULAR MAPPING AND ABLATION - FIRST EXPERIENCE21PACED FRACTIONATION DETECTION AS A TOOL FOR MAPPING SCARS IN VT22DOES USE OF CONTACT-FORCE SENSING CATHETERS IMPROVE THE OUTCOME OF ABLATION OF VENTRICULAR TACHYCARDIA?23RETROGRADE AORTIC ACCESS OF THE PULMONARY VENOUS ATRIUM PROVIDES EQUIVALENT OUTCOMES TO RIGHT ATRIAL OR TRANSEPTAL ACCESS OF THE LEFT ATRIUM IN PATIENTS WITH CONGENITAL HEART DISEASE24COMPUTATIONAL THREE-DIMENSION LEFT ATRIAL APPENDAGE WALL THICKNESS MAPS AND HISTOLOGICAL ANALYSIS TO GUIDE LEFT ATRIAL APPENDAGE ELECTRICAL ISOLATIONPacing & Devices25IDENTIFYING THE OPTIMAL LOCATION FOR LV ENDOCARIDAL PACING:RESULTS FROM A MULTICENTRE INTERNATIONAL REGISTRY OF LV ENDOCARDIAL PACING26UK MULTI-CENTRE REGISTRY OF TRANSVENOUS LEAD EXTRACTION: CLINICAL OUTCOME USING TRACTION, CUTTING SHEATHS AND LASER TECHNIQUES27SKIN FISTULA FORMATION - A NEW EXPERIENCE WITH THE NEW TYRX ABSORBABLE ANTIMICROVIAL ENVELOPE28BIFOCAL RIGHT VENTRICULAR PACING IN PATIENTS WITH FAILED CORONARY-SINUS LEAD IMPLANTS: LONG-TERM RESULTS FROM MULTICENTRE REGISTRY29REAL TIME X-MRI GUIDED LEFT VENTRICULAR LEAD IMPLANTATION FOR TARGETED DELIVERY OF CARDIAC RESYNCHRONIZATION THERAPY30ACUTE AND CHRONIC PERFORMANCE OF COMMUNICATING LEADLESS ANTI-TACHYCARDIA PACEMAKER AND SUBCUTANEOUS IMPLANTABLE DEFIBRILLATOR

Author

Evans, J.M., primary, Silberbauer, John, primary, Glover, B., primary, Kontogeorgis, A., primary, McLellan, A.J.A., primary, Panikker, S., primary, Sieniewicz, B.J., primary, Martin, C.A., primary, Burg, M.R., primary, Providencia, R., primary, Behar, J.M., primary, Burke, M.C., primary, Withers, K.L., additional, White, J., additional, Lencioni, M., additional, Carolan-Rees, G., additional, Wood, K.A., additional, Patrick, H., additional, Griffith, M., additional, Gomes, J., additional, Kirubakaran, S., additional, O'Nunain, S., additional, Bencat, M., additional, McCready, J., additional, Michael, K., additional, Hashemi, J., additional, Gupta, D., additional, Akl, S., additional, Redfearn, D., additional, Lim, E., additional, Panikker, S., additional, Butcher, C., additional, Khan, H., additional, Mantziari, L., additional, Jarman, J.W.E., additional, Hussain, W., additional, Jones, D., additional, Clague, J.R., additional, Ernst, S., additional, Markides, V., additional, Wong, T., additional, Ezzat, V.A., additional, Schilling, R.J., additional, Lowe, M.D., additional, Whitaker, J., additional, Virmani, R., additional, Kutys, R., additional, Fastl, T., additional, Haldar, S., additional, O'Neill, M., additional, Corado, C., additional, Nicol, E., additional, Foran, J.P., additional, Niederer, S., additional, Behar, J., additional, Sohal, M., additional, Jais, P., additional, Derval, N., additional, Spragg, D., additional, Van Gelder, B., additional, Bracke, F., additional, Steendijk, P., additional, Rinaldi, C.A., additional, Chooneea, B., additional, Gajendragadkar, P.R., additional, Ahsan, S., additional, Begley, D.A., additional, Dhinoja, M., additional, Earley, M.J., additional, Finlay, M., additional, Grace, A.A., additional, Heck, P.M., additional, Hunter, R.J., additional, Lambiase, P.D., additional, Rowland, E., additional, Segal, O.R., additional, Sporton, S., additional, Virdee, M.S., additional, Chow, A., additional, Apap Bologna, R., additional, Camilleri, W., additional, Sammut, M.A., additional, Aquilina, O., additional, Barra, S., additional, Papageorgiou, N., additional, Falconer, D., additional, Duehmke, R., additional, Rehal, O., additional, Ezzat, V., additional, Ioannou, A., additional, Segal, O., additional, Lowe, M., additional, Lambiase, P., additional, Agarwal, S., additional, Chow, A.W., additional, Toth, D., additional, Mountney, P., additional, Reiml, S., additional, Panayioutu, M., additional, Brost, A., additional, Fahn, B., additional, Patel, N.R., additional, Claridge, S., additional, Jackson, T., additional, Adhya, S., additional, Sieniwicz, B., additional, Razavi, R., additional, Rhode, K., additional, Tjong, F.V.Y., additional, Brouwer, T.F., additional, Koop, B., additional, Soltis, B., additional, Shuros, A., additional, and Knops, R.E., additional

Published
2016
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27. ISCHAEMIC HEART DISEASE

Author

Baker, C, Barnes, E, Bhatia, V, Desilva, R, Earley, M, Fox, K, Gorog, D, Jenkins, G, Kaprilian, R, Kapur, A, Khan, M, Lambiese, P, Markides, V, Poullis, M, Ramrakha, P, Strange, J, Wasan, B, and Walker, H

Subjects
Coronary heart disease -- Care and treatment, Stent (Surgery) -- Usage, Alternative medicine -- Usage, Health, Care and treatment, Usage
Abstract

Bored with PTCA? What about carotid stenting? The more adventurous interventionalist is always on the lookout for a new procedure. The Lancer offers what looks like equivalence at three years [...]

Published
2001

28. BASIC RESEARCH

Author

Baker, C, Barnes, E, Bhatia, V, Desilva, R, Earley, M, Fox, K, Gorog, D, Jenkins, G, Kaprilian, R, Kapur, A, Khan, M, Lambiese, P, Markides, V, Poullis, M, Ramrakha, P, Strange, J, Wasan, B, and Walker, H

Subjects
Coronary heart disease -- Research -- Health aspects, Anticholesteremic agents -- Health aspects -- Research, Health, Research, Health aspects
Abstract

The many actions of statins: Statins not only lower cholesterol, they also have potent effects on nitric oxide production, have immunomodulatory properties, and inhibit smooth muscle proliferation. Most of these [...]

Published
2001

29. GENERAL CARDIOLOGY

Author

Baker, C, Barnes, E, Bhatia, V, Desilva, R, Earley, M, Fox, K, Gorog, D, Jenkins, G, Kaprilian, R, Kapur, A, Khan, M, Lambiese, P, Markides, V, Poullis, M, Ramrakha, P, Strange, J, Wasan, B, and Walker, H

Subjects
Cardiovascular agents -- Health aspects, Pregnancy -- Health aspects, Cardiac patients -- Health aspects -- Drug therapy, Heart failure -- Drug therapy, Health, Drug therapy, Health aspects
Abstract

Having babies is risky, especially if the heart suffered the first time: Little is known about the outcomes of subsequent pregnancies in women who have had peripartum cardiomyopathy, a rare [...]

Published
2001

30. HYPERTENSION

Author

Baker, C, Barnes, E, Bhatia, V, Desilva, R, Earley, M, Fox, K, Gorog, D, Jenkins, G, Kaprilian, R, Kapur, A, Khan, M, Lambiese, P, Markides, V, Poullis, M, Ramrakha, P, Strange, J, Wasan, B, and Walker, H

Subjects
Coronary heart disease -- Diagnosis, Blood pressure -- Measurement, Heart -- Contraction, Health, Diagnosis, Measurement
Abstract

Systolic BP is better than diastolic BP or pulse pressure: In the cardiovascular health study, 5888 adults> 65 years were followed for an average of 6.7 years. There were 572 [...]

Published
2001

31. LACK OF SPECIFICITY OF ECTOPY-PROVOKING MANOEUVRES USED DURING MAPPING OF FOCAL ATRIAL FIBRILLATION

Author

Markides, V, Schilling, R J., Chow, A W C, Peters, N S., and Davies, D Wyn

Subjects
Heart -- Abnormalities, Atrial fibrillation -- Observations, Tachycardia -- Observations, Health
Abstract

Episodes of atrial ectopy/tachycardia (LAT) that may initiate atrial fibrillation (AF) are often infrequent and non-sustained, making focal AF mapping difficult. Although various manoeuvres may provoke LATs, the clinical relevance [...]

Published
2001

32. ANATOMICAL BASIS FOR A LINE OF BLOCK IN THE PULMONARY VEIN REGION OF THE HUMAN LEFT ATRIUM

Author

Markides, V, Ho, S Y., Schilling, R J., Chow, A W C, Davies, D Wyn, and Peters, N S.

Subjects
Heart atrium -- Physiological aspects, Atrial fibrillation -- Causes of -- Physiological aspects, Anatomy -- Physiological aspects, Heart -- Physiological aspects, Health
Abstract

S Y Ho [1] The relation between fibre orientation and activation patterns in the human left atrial (LA) endocardium has not been previously examined. We examined the gross anatomy and [...]

Published
2001

33. PATTERNS OF ACTIVATION OF THE HUMAN LEFT ATRIUM DURING SINUS RHYTHM, PACING AND ATRIAL FIBRILLATION, USING NON-CONTACT MAPPING

Author

Markides, V, Schilling, R J., Chow, A W C, Davies, D Wyn, and Peters, N S.

Subjects
Heart -- Abnormalities, Atrial fibrillation -- Physiological aspects, Surgery -- Planning -- Physiological aspects, Company business planning, Health
Abstract

The patterns of activation of the human left atrial (LA) endocardium have not been fully described and may be important in the pathogenesis and treatment of atrial fibrillation (AF). We [...]

Published
2001

37. General cardiology. (Journal Scan)

Author

Baker, C., Barnes, E., Bhatia, V., Desilva, R., Earley, M., Fox, K., Gorog, D., Jenkins, G., Kaprilian, R., Kapur, A., Khan, M., Lambiese, P., Markides, V., Poullis, M., Ramrakha, P., Strange, J., Wasan, B., and Walker, H.

Subjects
Cardiology -- Research, Health, Research
Abstract

AICD without electrical testing? * Patients with reduced ejection fractions and ventricular arrhythmias on electrophysiological testing or abnormal signal averaged ECGs live longer with an automatic implantable cardioverter-defibrillator (AICD) than [...]

Published
2002

38. Ischaemic heart disease. (Journal Scan)

Author

Baker, C., Barnes, E., Bhatia, V., Desilva, R., Earley, M., Fox, K., Gorog, D., Jenkins, G., Kaprilian, R., Kapur, A., Khan, M., Lambiese, P., Markides, V., Poullis, M., Ramrakha, P., Strange, J., Wasan, B., and Walker, H.

Subjects
Coronary heart disease -- Research, Health, Research
Abstract

Off-pump CABG after carotid surgery is safe * Patients with combined coronary and carotid artery disease are at high risk of perioperative stroke and myocardial infarction. Of 2556 patients scheduled [...]

Published
2002

39. JournalScan

Author

Baker, C., Barnes, E., Bhatia, V., Desilva, R., Earley, M., Fox, K., Gorog, D., Jenkins, G., Kaprilian, R., Kapur, A., Khan, M., Lambiese, P., Markides, V., Poullis, M., Ramrakha, P., Strange, J., Wasan, B., and Walker, H.

Subjects
Heart diseases -- Care and treatment, Cardiology -- Care and treatment, Ischemia -- Care and treatment, Hypertension -- Care and treatment, Health, Care and treatment
Abstract

Ischaemic heart disease Antioxidants may attenuate the benefits of lipid lowering * In a three year, double blind trial, 160 patients with coronary disease, low high density lipoprotein (HDL) cholesterol [...]

Published
2002

40. Poster Session 3

Author

Fabbri, G. M. T., primary, Baldasseroni, S., additional, Panuccio, D., additional, Zoni Berisso, M., additional, Scherillo, M., additional, Lucci, D., additional, Di Pasquale, G., additional, Mathieu, G., additional, Burazor, I., additional, Burazor, M., additional, Perisic, Z., additional, Atanaskovic, V., additional, Erakovic, V., additional, Stojkovic, A., additional, Vogtmann, T., additional, Schoebel, C., additional, Sogorski, S., additional, Sebert, M., additional, Schaarschmidt, J., additional, Fietze, I., additional, Baumann, G., additional, Penzel, T., additional, Mornos, C., additional, Ionac, A., additional, Cozma, D., additional, Dragulescu, D., additional, Mornos, A., additional, Petrescu, L., additional, Pescariu, L., additional, Brembilla-Perrot, B., additional, Khachab, H., additional, Lamberti, F., additional, Bellini, C., additional, Remoli, R., additional, Cogliandro, T., additional, Nardo, R., additional, Bellusci, F., additional, Mazzuca, V., additional, Gaspardone, A., additional, Aguinaga Arrascue, L. E., additional, Bravo, A., additional, Garcia Freire, P., additional, Gallardo, P., additional, Hasbani, E., additional, Quintana, R., additional, Dantur, J., additional, Inoue, K., additional, Ueoka, A., additional, Tsubakimoto, Y., additional, Sakatani, T., additional, Matsuo, A., additional, Fujita, H., additional, Kitamura, M., additional, Wegrzynowska, M., additional, Konduracka, E., additional, Pietrucha, A. Z., additional, Mroczek-Czernecka, D., additional, Paradowski, A., additional, Bzukala, I., additional, Nessler, J., additional, Igawa, O., additional, Adachi, M., additional, Atarashi, H., additional, Kusama, Y., additional, Kodani, E., additional, Okazaki, R., additional, Nakagomi, A., additional, Endoh, Y., additional, Baez-Escudero, J. L., additional, Dave, A. S., additional, Sasaridis, C. M., additional, Valderrabano, M., additional, Tilz, R., additional, Bai, R., additional, Di Biase, L., additional, Gallinghouse, G. J., additional, Gibson, D., additional, Pisapia, A., additional, Wazni, O., additional, Natale, A., additional, Arujuna, A., additional, Karim, R., additional, Rinaldi, A., additional, Cooklin, M., additional, Rhode, K., additional, Razavi, R., additional, O'neill, M., additional, Gill, J., additional, Kusa, S., additional, Komatsu, Y., additional, Kakita, K., additional, Takayama, K., additional, Taniguchi, H., additional, Otomo, K., additional, Iesaka, Y., additional, Ammar, S., additional, Reents, T., additional, Fichtner, S., additional, Wu, J., additional, Zhu, P., additional, Kolb, C., additional, Hessling, G., additional, Deisenhofer, I., additional, Gilbert, G., additional, Mohanty, P., additional, Cunningham, J., additional, Metz, T., additional, Horton, R., additional, Tao, S., additional, Yamauchi, Y., additional, Okada, H., additional, Maeda, S., additional, Obayashi, T., additional, Isobe, M., additional, Chan, J., additional, Johar, S., additional, Wong, T., additional, Markides, V., additional, Hussain, W., additional, Konstantinidou, M., additional, Wissner, E., additional, Fuernkranz, A., additional, Yoshiga, Y., additional, Metzner, A., additional, Kuck, K.- H., additional, Ouyang, F., additional, Kettering, K., additional, Gramley, F., additional, Mollnau, H., additional, Weiss, C., additional, Bardeleben, S., additional, Biasco, L., additional, Scaglione, M., additional, Caponi, D., additional, Di Donna, P., additional, Sergi, D., additional, Cerrato, N., additional, Blandino, A., additional, Gaita, F., additional, Fiala, M., additional, Wichterle, D., additional, Sknouril, L., additional, Bulkova, V., additional, Chovancik, J., additional, Nevralova, R., additional, Pindor, J., additional, Januska, J., additional, Choi, J. I., additional, Ban, J. E., additional, Yasutsugu, N., additional, Park, J. S., additional, Jung, J. S., additional, Lim, H. E., additional, Park, S. W., additional, Kim, Y. H., additional, Kuhne, M., additional, Reichlin, T., additional, Ammann, P., additional, Schaer, B., additional, Osswald, S., additional, Sticherling, C., additional, Ohe, M., additional, Goya, M., additional, Hiroshima, K., additional, Hayashi, K., additional, Makihara, Y., additional, Nagashima, M., additional, Fukunaga, M., additional, An, Y., additional, Dorwarth, U., additional, Schmidt, M., additional, Wankerl, M., additional, Krieg, J., additional, Straube, F., additional, Hoffmann, E., additional, Kathan, S., additional, Defaye, P., additional, Mbaye, A., additional, Cassagneau, R., additional, Gagniere, V., additional, Jacon, P., additional, Pokushalov, E., additional, Romanov, A., additional, Artemenko, S., additional, Shabanov, V., additional, Elesin, D., additional, Stenin, I., additional, Turov, A., additional, Losik, D., additional, Kondo, K., additional, Miake, J., additional, Yano, A., additional, Ogura, K., additional, Kato, M., additional, Shigemasa, C., additional, Sekiguchi, Y., additional, Tada, H., additional, Yoshida, K., additional, Naruse, Y., additional, Yamasaki, H., additional, Igarashi, M., additional, Machino, T., additional, Aonuma, K., additional, Chen, S., additional, Liu, S., additional, Chen, G., additional, Meng, W., additional, Zhang, F., additional, Yan, Y., additional, Sciarra, L., additional, Dottori, S., additional, Lanzillo, C., additional, De Ruvo, E., additional, De Luca, L., additional, Minati, M., additional, Lioy, E., additional, Calo', L., additional, Lin, J., additional, Nie, Z., additional, Zhu, M., additional, Wang, X., additional, Zhao, J., additional, Hu, W., additional, Tao, H., additional, Ge, J., additional, Johansson, B., additional, Houltz, B., additional, Edvardsson, N., additional, Schersten, H., additional, Karlsson, T., additional, Wandt, B., additional, Berglin, E., additional, Hoyt, R. 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P., additional, Louis-Simonet, M., additional, Hugli, O., additional, Yersin, B., additional, Schlaepfer, J., additional, Mischler, C., additional, Pruvot, E., additional, Occhetta, E., additional, Frascarelli, F., additional, Burali, A., additional, and Dovellini, E., additional

Published
2011
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41. Abstracts: Tools to facilitate ablation procedures

Author

Schwagten, B., primary, Schwagten, B. K. R., additional, Szili-Torok, T., additional, Rivero-Ayerza, M., additional, Thornton, A., additional, Van Belle, Y., additional, Jordaens, L., additional, Leiria, T. L. L., additional, Kus, T., additional, Hadjis, T. A., additional, Essebag, V., additional, Sturmer, M. L., additional, Soubelet, E., additional, Krum, D., additional, Delavelle, A., additional, Varray, F., additional, Hare, J., additional, Vaillant, R., additional, Choudhuri, I., additional, Sra, J., additional, Vollmann, D., additional, Luethje, L., additional, Seegers, J., additional, Hasenfuss, G., additional, Zabel, M., additional, Johar, S., additional, Jones, D. G., additional, Lyne, J. C., additional, Kaba, R. A., additional, Wong, T., additional, Markides, V., additional, Clague, J. R., additional, Ernst, S., additional, Hlivak, P., additional, Mlcochova, H., additional, Peichl, P., additional, Cihak, R., additional, Wichterle, D., additional, and Kautzner, J., additional

Published
2009
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47. Heart failure. (Journal Scan)

Author

Baker, C., Barnes, E., Bhatia, V., Desilva, R., Earley, M., Fox, K., Gorog, D., Jenkins, G., Kaprilian, R., Kapur, A., Khan, M., Lambiese, P., Markides, V., Poullis, M., Ramrakha, P., Strange, J., Wasan, B., and Walker, H.

Subjects
Heart failure -- Physiological aspects, Health, Physiological aspects
Abstract

Clinical assessments of heart failure are flawed * The rule of halves states that 50% of patients treated for heart failure do not have systolic dysfunction. This study of 225 [...]

Published
2002

48. Catheter inversion: a technique to complete isthmus ablation and cure atrial flutter.

Author

Sporton SC, Davies DW, Earley MJ, Markides V, Nathan AW, and Schilling RJ

Abstract

Cure of typical atrial flutter (AFL) by catheter ablation to produce bidirectional block across the tricuspid annulus-inferior vena cava isthmus (IS) is highly effective, but failures may occur. We describe a technique that may allow creation of bidirectional block where a conventional strategy has failed. AFL ablation was performed using the conventional approach with a mapping/ablation (ablation) catheter introduced via the right femoral vein (RFV) to create a line of bidirectional block across the IS. If this was not achieved after five passes of the ablation catheter from the tricuspid annulus to the inferior vena cava (IVC) a catheter inversion technique was used. This allowed stable positioning of the ablation catheter at the IVC end of the isthmus. In 11 patients, a mean of 17 (range 3 to 45) radiofrequency (RF) applications was given before the catheter inversion technique was applied. Following catheter inversion a mean of 4 (1 to 14) further RF applications achieved bidirectional isthmus block in every patient. No complications occurred. Catheter inversion provides a simple, safe, and effective means of achieving bidirectional isthmus conduction block in cases where a conventional ablation strategy might have failed. [ABSTRACT FROM AUTHOR]

Published
2004
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