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In this article, joining the History of Linguistic Ideas and Pechetian Discourse Analysis, we aim to understand how the work with the lexicon, articulating lexicology, lexicography, and semantics, operates in education and language public policies from the second half of the century XX, as a way of managing the meanings and the subject in a neoliberal discursive formation. The discursive management of language by the lexicon means the normalization of meanings, therefore, of the subject, in the search for a semantically normal – adequate – world, in which imaginatively stable boundaries and limits can be established. In these demarcations and divisions, we have the confrontation of the symbolic with the political. We take as material for description-analysis, a series formed by the words adequacy, adequate (verb), adequate (adj) for the centrality they have had since the 1960s/1970s, in language policies, in school practices, and in life in society, dialoguing with the series: conversion, convert, converted, and regeneration, regenerate, regenerated, so that we could observe the movement of discursive formations, in which a (discursive) memory recovers, through repetition and displacement, meanings that ensure the space of stability and, at the same time, that open up to the not logically stabilized.

This study evaluated the preclinical effect of obesity on the ventricular remodeling in adolescents with morbid obesity, and determined if subjects labelled as metabolically healthy obesity (MHO) presented better heart index than those with metabolically unhealthy obesity (MUO). Prospective case-control research of 45 adolescents (14-year-old) with morbid obesity and 25 normal weight adolescents' gender- and age-matched with Tanner stage 4-5. Left ventricle (LV) was evaluated by conventional Doppler echocardiography, tissue Doppler imaging and two-dimensional speckle tracking echocardiography. Compared to normal-weight subjects, adolescents with morbid obesity presented a high percentage of pathological LV geometry (87%; p

UIDB/05021/2020 UIDP/05021/2020 publishersversion published

UIDB/05021/2020 UIDP/05021/2020 publishersversion published

The stereotype of the Latin woman is commonly associated with sexuality. Brazilians seem to be particularly burdened by this stigma among Latin women worldwide. As immigrants, intersected by other matrices of oppression in addition to those of gender and race, for example, these women bear various marks remaining from Eurocentric coloniality that belittles and silences them (Mignolo, 2000/2003), a circumstance that is aggravated when the country of emigration is their coloniser. This article explores resorting to cyberspace as a forum for denunciation and feminist activism through a case study of the profile @brasileirasnaosecalam based on content analysis. The project appeared on the digital social network Instagram to anonymously report the harassment, discrimination and prejudice that Brazilian immigrant women suffer in Portugal, specifically for carrying their own nationality. Thus, through cyberactivism, which is also feminist activism, women are now experiencing a new cycle of political opportunities driven by the building and consolidation of ties among them around the globe, breaking down binarisms, including those between the first and the third world, in an appeal to cross-border articulation (Timeto, 2019). That shows the relevance of pursuing an ontological vision underpinned by a decolonial and intersectional feminist perspective that uses cyberfeminism as an ally to interconnect the digital and the real space. O estereótipo da mulher latina é comummente associado à sexualidade. Dentre elas, as mulheres brasileiras parecem carregar ainda mais este estigma mundo fora. Enquanto imigrantes, interseccionadas por outras matrizes de opressão além de género e raça, por exemplo, estas mulheres veem-se sujeitas a diversas marcas ainda remanescentes da colonialidade eurocêntrica que as inferioriza e silencia (Mignolo, 2000/2003), o que é agravado quando o país de emigração é o seu colonizador. Este artigo explora a utilização do ciberespaço como campo de denúncia e ativismo feminista através do estudo de caso do perfil @brasileirasnaosecalam, a partir da análise de conteúdo. O projeto surge na rede social digital Instagram com o intuito de denunciar, de maneira anónima, assédios, discriminações e preconceitos que mulheres imigrantes brasileiras sofrem em Portugal, especificamente por carregarem consigo a sua própria nacionalidade. Assim, através do ciberativismo, também feminista, as mulheres dispõem de um novo ciclo político de oportunidades impulsionadas pela construção e consolidação de laços entre elas ao redor do globo, rompendo binarismos, também entre primeiro e terceiro mundo, num apelo à articulação entre fronteiras (Timeto, 2019). Constata-se a relevância de empreender uma visão ontológica que se apoie numa perspetiva feminista decolonial e interseccional que utiliza o ciberfeminismo como aliado de interconexão entre o espaço digital e o real.

This study investigates to what extent specific features of news articles about election campaigns impact reader engagement and civility in news comments. Using content analysis of articles (N = 830) and comments (N = 29,421) published during the 2015 Portuguese Legislative elections, we test the impact of negative coverage, issue coverage and game coverage (politics as a game) on the number of comments that an article receives and the level of civility thereof. Additionally, we explore how affective polarisation of a commenter may moderate the effects on incivility. Findings show that negativity towards political actors in an article is tied to both an increase in the number of comments and their level of incivility. Game coverage only led to a significant increase in the number of comments, while actor-related positivity was also related to an increase in incivility. Issue coverage had neither positive nor negative effects. The results inform newsrooms and academics about the implications of different types of election reporting, while accounting for features of news articles that are typically not integrated in a single study., The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This research was funded by POCH Programa Operacional Capital Humano, participated by the European Social Fund and by national funds by the MCTES by an individual doctoral scholarship granted by Fundacao para a Ciencia e Tecnologia (SFRH/BD/103335/2014). Text revision funded by Fundacao para a Ciencia e Tecnologia through project UIDB/00736/2020.

Background: The presence of toxic metals in human populations is strongly associated with chronic diseases. Aim: To determine levels of lead, chromium, cadmium, mercury and inorganic arsenic (AsIn) in the general population aged over 5 years in Antofagasta, Chile. Material and Methods: People living in Urban Antofagasta for at least five years were considered eligible. Biological samples were obtained to measure heavy metals. Results: One thousand two hundred three participants with a median age of 43 years (656 women) were studied. Their mean time of residence in the city was 30 years, and 52% smoked. Eight percent of the adult population and 12% of children had AsIn values above 35 µg/L, while 75% of the population had levels below 21.9 µg/L. The other metals were below the risk levels defined by the health authority (10 µg/L for chromium, 10 µg/L for mercury, 2 µg/L for cadmium, 5 and 10 μg/dL for blood lead for children and adults, respectively). The factors associated with high levels of AsIn in adults were male sex, living more than 200 meters from monitoring points, and low schooling. In children, the associated variables were high intake of seafood products and having a caregiver with less than 8 years of schooling. Contrary to expectations, the greatest risk of presenting altered levels of the metals occurred in the population living more than 500 meters from the identified risk sources (90% of the population). Conclusions: The findings of this study suggest that all potential sources of exposure to AsIn should be evaluated, and surveillance actions should be established to reduce involuntary exposure to this metalloid.

O estereótipo da mulher latina é comummente associado à sexualidade. Dentre elas, as mulheres brasileiras parecem carregar ainda mais este estigma mundo fora. Enquanto imigrantes, interseccionadas por outras matrizes de opressão além de género e raça, por exemplo, estas mulheres veem-se sujeitas a diversas marcas ainda remanescentes da colonialidade eurocêntrica que as inferioriza e silencia (Mignolo, 2000/2003), o que é agravado quando o país de emigração é o seu colonizador. Este artigo explora a utilização do ciberespaço como campo de denúncia e ativismo feminista através do estudo de caso do perfil @brasileirasnaosecalam, a partir da análise de conteúdo. O projeto surge na rede social digital Instagram com o intuito de denunciar, de maneira anónima, assédios, discriminações e preconceitos que mulheres imigrantes brasileiras sofrem em Portugal, especificamente por carregarem consigo a sua própria nacionalidade. Assim, através do ciberativismo, também feminista, as mulheres dispõem de um novo ciclo político de oportunidades impulsionadas pela construção e consolidação de laços entre elas ao redor do globo, rompendo binarismos, também entre primeiro e terceiro mundo, num apelo à articulação entre fronteiras (Timeto, 2019). Constata-se a relevância de empreender uma visão ontológica que se apoie numa perspetiva feminista decolonial e interseccional que utiliza o ciberfeminismo como aliado de interconexão entre o espaço digital e o real., The stereotype of the Latin woman is commonly associated with sexuality. Brazilians seem to be particularly burdened by this stigma among Latin women worldwide. As immigrants, intersected by other matrices of oppression in addition to those of gender and race, for example, these women bear various marks remaining from Eurocentric coloniality that belittles and silences them (Mignolo, 2000/2003), a circumstance that is aggravated when the country of emigration is their coloniser. This article explores resorting to cyberspace as a forum for denunciation and feminist activism through a case study of the profile @brasileirasnaosecalam based on content analysis. The project appeared on the digital social network Instagram to anonymously report the harassment, discrimination and prejudice that Brazilian immigrant women suffer in Portugal, specifically for carrying their own nationality. Thus, through cyberactivism, which is also feminist activism, women are now experiencing a new cycle of political opportunities driven by the building and consolidation of ties among them around the globe, breaking down binarisms, including those between the first and the third world, in an appeal to cross-border articulation (Timeto, 2019). That shows the relevance of pursuing an ontological vision underpinned by a decolonial and intersectional feminist perspective that uses cyberfeminism as an ally to interconnect the digital and the real space.

Immune checkpoint inhibitors (ICIs) have revolutionized the treatment landscape of non-small cell lung cancer (NSCLC), either used in monotherapy or in combination with chemotherapy. While some patients achieve durable responses, some will not get benefit from this treatment. Early identification of non- responder patients could avoid unnecessary treatment, potentially serious immune-related adverse events and reduce treatment costs. PD-L1 expression using immunohistochemistry is the only approved biomarker for the selection of patients that can benefit from immunotherapy. However, application of PD-L1 as a biomarker of treatment efficacy shows many deficiencies probably due to the complexity of the tumor microenvironment and the technical limitations of the samples. Thus, there is an urgent need to find other biomarkers, ideally blood biomarkers to help us to identify different subgroups of patients in a minimal invasive way. In this review, we summarize the emerging blood-based markers that could help to predict the response to ICIs in NSCLC.

O estereótipo da mulher latina é comummente associado à sexualidade. Dentre elas, as mulheres brasileiras parecem carregar ainda mais este estigma mundo fora. Enquanto imigrantes, interseccionadas por outras matrizes de opressão além de género e raça, por exemplo, estas mulheres veem-se sujeitas a diversas marcas ainda remanescentes da colonialidade eurocêntrica que as inferioriza e silencia (Mignolo, 2000/2003), o que é agravado quando o país de emigração é o seu colonizador. Este artigo explora a utilização do ciberespaço como campo de denúncia e ativismo feminista através do estudo de caso do perfil @brasileirasnaosecalam, a partir da análise de conteúdo. O projeto surge na rede social digital Instagram com o intuito de denunciar, de maneira anónima, assédios, discriminações e preconceitos que mulheres imigrantes brasileiras sofrem em Portugal, especificamente por carregarem consigo a sua própria nacionalidade. Assim, através do ciberativismo, também feminista, as mulheres dispõem de um novo ciclo político de oportunidades impulsionadas pela construção e consolidação de laços entre elas ao redor do globo, rompendo binarismos, também entre primeiro e terceiro mundo, num apelo à articulação entre fronteiras (Timeto, 2019). Constata-se a relevância de empreender uma visão ontológica que se apoie numa perspetiva feminista decolonial e interseccional que utiliza o ciberfeminismo como aliado de interconexão entre o espaço digital e o real. The stereotype of the Latin woman is commonly associated with sexuality. Brazilians seem to be particularly burdened by this stigma among Latin women worldwide. As immigrants, intersected by other matrices of oppression in addition to those of gender and race, for example, these women bear various marks remaining from Eurocentric coloniality that belittles and silences them (Mignolo, 2000/2003), a circumstance that is aggravated when the country of emigration is their coloniser. This article explores resorting to cyberspace as a forum for denunciation and feminist activism through a case study of the profile @brasileirasnaosecalam based on content analysis. The project appeared on the digital social network Instagram to anonymously report the harassment, discrimination and prejudice that Brazilian immigrant women suffer in Portugal, specifically for carrying their own nationality. Thus, through cyberactivism, which is also feminist activism, women are now experiencing a new cycle of political opportunities driven by the building and consolidation of ties among them around the globe, breaking down binarisms, including those between the first and the third world, in an appeal to cross-border articulation (Timeto, 2019). That shows the relevance of pursuing an ontological vision underpinned by a decolonial and intersectional feminist perspective that uses cyberfeminism as an ally to interconnect the digital and the real space. publishersversion published

Pensar e compreender o discurso pedagógico no processo histórico e político mais amplo da escolarização do português no Brasil, em diferentes conjunturas, em que uma memória histórica estruturada pela escravidão continua funcionando, tem sido nosso objeto de estudo. Neste artigo, visamos analisar duas noções – “texto” e “linguagens”-, introduzidas nos anos 1960/1970 nas práticas escolares, através de políticas públicas e de sua didatização, sob a ideologia da comunicação, marcadas pela dominância do tecnicismo, do pragmatismo e do funcionalismo, sustentados, por sua vez, pelo empiricismo, pelo positivismo, na instrumentalização da(s) língua(s) do Brasil, pressupostos em certas teorias. Objetivamos, neste percurso, fazer uma leitura discursiva, da perspectiva materialista, das formas de subjetivação em seus desdobramentos, que indique caminhos a serem explorados se queremos construir a sempre adiada escola republicana de qualidade como direito de todos os brasileiros em que o ensino do português como língua nacional não silencie a diversidade individual e coletiva.

This study evaluated the preclinical effect of obesity on the ventricular remodeling in adolescents with morbid obesity, and determined if subjects labelled as metabolically healthy obesity (MHO) presented better heart index than those with metabolically unhealthy obesity (MUO). Prospective case-control research of 45 adolescents (14-year-old) with morbid obesity and 25 normal weight adolescents' gender- and age-matched with Tanner stage 4-5. Left ventricle (LV) was evaluated by conventional Doppler echocardiography, tissue Doppler imaging and two-dimensional speckle tracking echocardiography. Compared to normal-weight subjects, adolescents with morbid obesity presented a high percentage of pathological LV geometry (87%; p0.01), and systolic and diastolic dysfunctions only detected by E/A ratio (2.0 vs 1.7, p0.01), global longitudinal strain (-21.0% vs -16.5%, p0.01), and early diastolic strain rate (3.2 vs 2.2, p0.01). A correlation was found between impaired cardiac index and body mass index (BMI), high blood pressure, hyperglycemia, low HDL-cholesterol and hypertriglyceridemia. BMI and HDL-cholesterol were the most significant independent variables. No significant differences were found in structural and functional cardiac index when MHO and MUO subjects were compared (global longitudinal strain: -17.0% vs -16.4%, p0.79). Morbidly obese adolescents have an abnormal LV geometry, closely related to BMI, and systolic and diastolic LV dysfunctions. Adolescents labelled as MHO, despite exhibiting better BMI and insulin-resistance values, present the same pathological heart changes as MUO.

Lockdown during the COVID-19 pandemic imposed changes in children’s daily routine that could lead to changes in behavior patterns. Using a survey targeted at children under 17 years of age, we described dietary (adherence to Mediterranean diet, AMD) and sleeping habits (disorders of initiating and maintaining sleep) after the implementation of lockdown, and examined the probability of the inadequate frequency of physical activity (PA) and use of TV and electronic devices (TV-ED) before and after lockdown through generalized estimating equation models, accounting for age and gender differences. From 3464 children included, 53.2% showed optimal AMD; 79.2% referred to delayed bedtime; and 16.3% were suspected of sleeping disorders after the implementation of lockdown. Delay in bedtime was more frequent among children older than 6 years, and inadequate sleeping hours among those younger than 11 years. There were no gender differences in AMD or sleeping habits. The odds of inadequate frequency of PA and TV-ED use were greater after lockdown, with a greater risk for TV-ED use. Boys were at greater risk of inadequate PA frequency and TV-ED use. Odds ratio of inadequate PA was greater at older ages. Lockdown could influence changes in children’s habits that could lead to risk factors for non-communicable diseases during adulthood if such behaviors are sustained over time.

UIDB/05021/2020 UIDP/05021/2020 O nosso objeto de estudo é resultado de uma bolsa de investigação atribuída pela Fundação Calouste Gulbenkian para uma investigação jornalística sobre a extrema direita na Europa, onde o potencial da “aliança estratégica” entre o jornalismo e a academia, enquanto elo de defesa e agente de resistência do jornalismo de investigação, teve aplicação plena. Neste capítulo, procuramos, pois, analisar em detalhe as dinâmicas produtivas de um projeto multidimensional, onde sobressai a formação de jovens jornalistas e as potencialidades de uma investigação em consórcio. Examinamos, por outro lado, o modo como as tentativas de intimidação e de assédio ao jornalista de investigação fizeram parte do próprio processo produtivo, enquadrando este caso específico num quadro mais vasto de assédio aos profissionais de jornalismo nas sociedades democráticas atuais e, em particular, no contexto português. Apesar dos efeitos negativos, acreditamos que a formação de um consórcio de jornalistas de investigação portugueses, em aliança estratégica com a academia, pode ser a solução que salvaguarde o futuro do jornalismo de investigação em Portugal. publishersversion published

This article deals with the popular contemporary television narrative from an analysis of the daily talk show presented by Cristina Ferreira on the SIC channel until July 17th 2020. The success of Cristina’s Program is framed from a historical point of view, establishing continuity with the work of Nelson Traquina, Big Show Media (1997). Cristina Ferreira is a celebrity of popular Portuguese television and builds in her show a gender performance grounded in the paradoxical logic of post-feminism.Her versatility is visible in the transversality of the dissemination strategy of the TV program on social networks, namely in Instagram and Facebook, where the audien- ces are broadened through the instrumental mobilization of other digital influencers., Este artigo aborda a narrativa televisiva contemporânea popular a partir de uma análise do talk show diário apresentado por Cristina Ferreira na SIC até 17 de julho de 2020. O sucesso do Programa da Cristina é enquadrado de um ponto de vista histórico, estabelecendo continuidades com a obra de Nelson Traquina, Big Show Media (1997). Cristina Ferreira é uma celebridade da televisão popular portuguesa e constrói no seu programa uma performance de género ancorada na lógica parado- xal do pós-feminismo. A sua versatilidade é visível na transversalidade da estratégia de divulgação do programa nas redes sociais, designadamente no Instagram e no Facebook, onde se ampliam os públicos através da mobilização instrumental de ou- tros influenciadores digitais.

UIDB/05021/2020 UIDP/05021/2020 Este artigo aborda a narrativa televisiva contemporânea popular a partir de uma análise do talk show diário apresentado por Cristina Ferreira na SIC até 17 de julho de 2020. O sucesso do Programa da Cristina é enquadrado de um ponto de vista histórico, estabelecendo continuidades com a obra de Nelson Traquina, Big Show Media (1997). Cristina Ferreira é uma celebridade da televisão popular portuguesa e constrói no seu programa uma performance de género ancorada na lógica parado- xal do pós-feminismo. A sua versatilidade é visível na transversalidade da estratégia de divulgação do programa nas redes sociais, designadamente no Instagram e no Facebook, onde se ampliam os públicos através da mobilização instrumental de ou- tros influenciadores digitais. This article deals with the popular contemporary television narrative from an analysis of the daily talk show presented by Cristina Ferreira on the SIC channel until July 17th 2020. The success of Cristina's Program is framed from a historical point of view, establishing continuity with the work of Nelson Traquina, Big Show Media (1997). Cristina Ferreira is a celebrity of popular Portuguese television and builds in her show a gender performance grounded in the paradoxical logic of post-feminism. Her versatility is visible in the transversality of the dissemination strategy of the TV program on social networks, namely in Instagram and Facebook, where the audiences are broadened through the instrumental mobilization of other digital influencers. publishersversion published