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to each of "our g-oups: group I subjects were given ipratropijn(I), group II chldren received salne solution (0,9% NaCli, g'oup III parents received a combination of fenoterol andipralropium IF!) and group IV child-en were given salbutamo, (S). Tal scores were similar at admission in all four groups(day OJ. A) day 1 Fl patients showed significant,y better Tal scores (p < C.05] than ail the other groups and f

A double blind prospective study was done in 120 infants with acute obstructive bronchial disease. One half of them received combined fenoterol-ipratropium solution by inhalation in three different dose schedules while the other half was given inhalation normal saline solution for comparative purposes. Statistical analysis showed a significant difference in favor of fenoterol-ipratropium treatment over controls as to severity of bronchial obstruction, days of recovery and the need of additional bronchodilator drugs. However, no significant differences in the response of these parameters were noted among patients receiving different dose schedules of fenoterol-ipratropium. The combination of fenoterol-ipratropium showed a beneficial bronchodilator effect in patients with acute obstructive bronchial disease.