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1. Recommendations for recognizing, risk stratifying, treating, and managing children and adolescents with hypoglycemia

Author

Stefano Zucchini, Stefano Tumini, Andrea Enzo Scaramuzza, Riccardo Bonfanti, Maurizio Delvecchio, Roberto Franceschi, Dario Iafusco, Lorenzo Lenzi, Enza Mozzillo, Stefano Passanisi, Claudia Piona, Ivana Rabbone, Novella Rapini, Andrea Rigamonti, Carlo Ripoli, Giuseppina Salzano, Silvia Savastio, Riccardo Schiaffini, Angela Zanfardino, Valentino Cherubini, Diabetes Study Group of the Italian Society for Pediatric Endocrinology Diabetes, Albino Claudia Accursia, Aloe Monica, Anzelotti Maria Teresa, Arnaldi Claudia, Barbetti Fabrizio, Bassi Marta, Berioli Maria Giulia, Bernardini Luca, Bertelli Enrica, Biagioni Martina, Bobbio Adriana, Bombaci Bruno, Bonfanti Riccardo, Bonura Clara, Bracciolini Giulia Patrizia, Bruzzese Mariella, Bruzzi Patrizia, Buono Pietro, Buscarino Piera, Cadario Francesco, Calcaterra Valeria, Calzi Elena, Cappa Marco, Cardani Roberta, Cardella Francesca, Cardinale Giuliana Marcella, Casertano Alberto, Castorani Valeria, Cauvin Vittoria, Cenciarelli Valentina, Ceruti Franco, Cherubini Valentino, Chiarelli Francesco, Chiari Giovanni, Cianfarani Stefano, Cicchetti Mario, Cipriano Paola, Cirillo Dante, Citriniti Felice, Coccioli Maria Susanna, Confetto Santino, Contreas Giovanna, Coro Anna, Correddu Antonella, Corsini Elisa, Crino’ Antonino, d’Annunzio Giuseppe, De Berardinis Fiorella, De Donno Valeria, De Filippo Gianpaolo, De Marco Rosaria, De Sanctis Luisa, Del Duca Elisabetta, Delvecchio Maurizio, Deodati Annalisa, Di Bonito Procolo, Di Candia Francesca, Faleschini Elena, Fattorusso Valentina, Favia Anna, Federico Giovanni, Felappi Barbara, Ferrari Mara, Ferrito Lucia, Fichera Graziella, Fontana Franco, Fornari Elena, Franceschi Roberto, Franco Francesca, Franzese Adriana, Frongia Anna Paola, Frontino Giulio, Gaiero Alberto, Galassi Sabrina Maria, Gallo Francesco, Gargantini Luigi, Giani Elisa, Gortan Anna Jolanda, Graziani Vanna, Grosso Caterina, Gualtieri Antonella, Guasti Monica, Guerraggio Lucia Paola, Guzzetti Chiara, Iafusco Dario, Iannicelli Gennaro, Iezzi Maria Laura, Ignaccolo Maria Giovanna, Innaurato Stefania, Inzaghi Elena, Iovane Brunella, Iughetti Lorenzo, Kaufmann Peter, La Loggia Alfonso, Lambertini Anna Giulia, Lapolla Rosa, Lasagni Anna, Lazzaro Nicola, Lazzeroni Pietro, Lenzi Lorenzo, Lera Riccardo, Levantini Gabriella, Lezzi Marilea, Lia Rosanna, Liguori Alice, Lo Presti Donatella, Lombardo Fortunato, Lonero Antonella, Longhi Silvia, Lorubbio Antonella, Lucchesi Sonia, Maccioni Rosella, Macedoni Maddalena, Macellaro Patrizia Cristiana, Madeo Simona Filomena, Maffeis Claudio, Mainetti Benedetta, Maltoni Giulio, Mameli Chiara, Mammì Francesco, Manca Bitti Maria Luisa, Mancioppi Valentina, Manco Melania, Marigliano Marco, Marino Monica, Marsciani Alberto, Matteoli Maria Cristina, Mazzali Elena, Minute Marta, Minuto Nicola, Monti Sara, Morandi Anita,, Morganti Gianfranco, Morotti Elisa, Mozzillo Enza, Musolino Gianluca, Olivieri Francesca, Ortolani Federica, Pampanini Valentina, Pardi Daniela, Pascarella Filomena, Pasquino Bruno, Passanisi Stefano, Patera Ippolita Patrizia, Pedini Annalisa, Pennati Maria Cristina, Peruzzi Sonia, Peverelli Paola, Pezzino Giulia, Piccini Barbara, Piccinno Elvira Eugenia Rosaria, Piona Claudia, Piredda Gavina, Piscopo Alessia, Pistone Carmelo, Pozzi Erica, Prandi Elena, Predieri Barbara, Prudente Sabrina, Pulcina Anna, Rabbone Ivana, Randazzo Emioli, Rapini Novella, Reinstadler Petra, Riboni Sara, Ricciardi Maria Rossella, Rigamonti Andrea, Ripoli Carlo, Rossi Virginia, Rossi Paolo, Rutigliano Irene, Sabbion Alberto, Salvatoni Alessandro, Salvo Caterina, Salzano Giuseppina, Sanseviero Mariateresa, Savastio Silvia, Savini Rosanna, Scanu Mariapiera, Scaramuzza Andrea Enzo, Schiaffini Riccardo, Schiavone Maurizio, Schieven Eleonardo, Scipione Mirella, Secco Andrea, Silvestri Francesca, Siri Giulia, Sogno Valin Paola, Sordelli Silvia, Spiri Daniele, Stagi Stefano, Stamati Filomena Andreina, Suprani Tosca, Talarico Valentina, Tiberi Valentina, Timpanaro Tiziana Antonia Lucia, Tinti Davide, Tirendi Antonina, Tomaselli Letizia Grazia, Toni Sonia, Torelli Cataldo, Tornese Gianluca, Trada Michela,, Trettene Adolfo Andrea, Tumini Stefano, Tumminelli Marilena, Valerio Giuliana, Vandelli Sara, Ventrici Claudia, Zampolli Maria, Zanatta Manuela, Zanfardino Angela, Zecchino Clara, Zonca Silvia, and Zucchini Stefano

Subjects
adolescents, automated insulin delivery, children, hypoglycemia, glucagon, oral glucose, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
Abstract

There has been continuous progress in diabetes management over the last few decades, not least due to the widespread dissemination of continuous glucose monitoring (CGM) and automated insulin delivery systems. These technological advances have radically changed the daily lives of people living with diabetes, improving the quality of life of both children and their families. Despite this, hypoglycemia remains the primary side-effect of insulin therapy. Based on a systematic review of the available scientific evidence, this paper aims to provide evidence-based recommendations for recognizing, risk stratifying, treating, and managing patients with hypoglycemia. The objective of these recommendations is to unify the behavior of pediatric diabetologists with respect to the timely recognition and prevention of hypoglycemic episodes and the correct treatment of hypoglycemia, especially in patients using CGM or advanced hybrid closed-loop systems. All authors have long experience in the specialty and are members of the Italian Society of Pediatric Endocrinology and Diabetology. The goal of treating hypoglycemia is to raise blood glucose above 70 mg/dL (3.9 mmol/L) and to prevent further decreases. Oral glucose at a dose of 0.3 g/kg (0.1 g/kg for children using “smart pumps” or hybrid closed loop systems in automated mode) is the preferred treatment for the conscious individual with blood glucose

Published
2024
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2. Gender minorities in breast cancer – Clinical trials enrollment disparities: Focus on male, transgender and gender diverse patients

Author

Miglietta, Federica, Pontolillo, Letizia, De Angelis, Carmine, Caputo, Roberta, Marino, Monica, Bria, Emilio, Di Rienzo, Rossana, Verrazzo, Annarita, Buonerba, Carlo, Tortora, Giampaolo, Di Lorenzo, Giuseppe, Del Mastro, Lucia, Giuliano, Mario, Montemurro, Filippo, Puglisi, Fabio, Guarneri, Valentina, De Laurentiis, Michelino, Scafuri, Luca, and Arpino, Grazia

Published
2024
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4. Does the use of electronic texts in small group reading instruction impact comprehension?

Author

Marino, Monica, Skidmore, David, and Hayhoe, Simon

Subjects
372.47, Reading Comprehension, E-books
Abstract

Due to the increased presence of e-books in primary schools, practitioners are wondering if e-text is ‘better’ for student reading comprehension than paper text. This dissertation, a small-scale, mixed-methods study, set out to examine differences in primary school student reading performance when using e-books versus paper books. The research is grounded in constructivist beliefs that learning is a co-created construct, shared between students and teachers. A review of the literature explores the concepts of e-book, reading comprehension, and how reading comprehension is measured, along with Puentadura’s 2006 SAMR model as a framework upon which to explore the impacts of educational technology. The study employs the Fountas and Pinnell Benchmark System to measure students’ reading levels before and after the data collection period. During the data collection period, the teacher taught small-group reading lessons, and half of the participants used e-books while the other half read paper copies of the same text. The study employs discourse analysis and thematic analysis to examine the impact of the text type on student comprehension. The findings suggest that more work is needed to determine the impact of e-text on student comprehension. However, in this exploratory study, the performance of students in the two groups appeared to be similar. The study found that the text-to-speech feature available on Kindle devices and its impact on reading comprehension require further examination. The findings suggested that Kindle might be considered a separate genre requiring its own explicit instruction, and more work will need to be done in order to bring teacher professional development in line with this suggestion.

Published
2020

6. Clinical features and evolution of bacterial infection-related acute-on-chronic liver failure

Author

Bhamidimarri, Kalyan, Boyer, Thomas D., Brodersen, Carlos, Campion, Daniela, Caraceni, Paolo, de Man, Robert A., Fassio, Eduardo, Fialla, Annette Dam, Gambino, Carmine, Gautam, Vikas, Gines, Pere, Hwang, Jae Seok, Kim, Hyoung Su, Kim, Jeong Han, Kumar, Pramod, Lattanz, Barbara, Lee, Tae Hee, Rinaldi Lesmana, Cosmas A., Maevskaya, Marina, Nath, Preetam, Navarro, Gustavo, Park, Ji-Won, Pinero, Gisela, Restellini, Sophie, Romero, Gustavo, Sevá -Pereira, Tiago, Simón-Talero, Macarena, Song, Do Seon, Suk, Ki Tae, Van Vlierberghe, Hans, Zaccherini, Giacomo, Wong, Florence, Piano, Salvatore, Singh, Virendra, Bartoletti, Michele, Maiwall, Rakhi, Alessandria, Carlo, Fernandez, Javier, Soares, Elza Cotrim, Kim, Dong Joon, Kim, Sung Eun, Marino, Monica, Vorobioff, Julio, Barea, Rita de Cassia Ribeiro, Merli, Manuela, Elkrief, Laure, Vargas, Victor, Krag, Aleksander, Singh, Shivaram Prasad, Lesmana, Laurentius Adrianto, Toledo, Claudio, Marciano, Sebastian, Verhelst, Xavier, Intagliata, Nicolas, Rabinowich, Liane, Colombato, Luis, Kim, Sang Gyune, Gerbes, Alexander, Durand, Francois, Roblero, Juan Pablo, Bruns, Tony, Yoon, Eileen Laurel, Girala, Marcos, Pyrsopoulos, Nikolaos T., Kim, Tae Hun, Yim, Sun Young, Juanola, Adria, Gadano, Adrian, and Angeli, Paolo

Published
2021
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9. Epidemiology and Effects of Bacterial Infections in Patients With Cirrhosis Worldwide

Author

Bartoletti, Michele, Brodersen, Carlos, Bruns, Tony, de Man, Robert A., Fialla, Annette Dam, Gambino, Carmine, Gautam, Vikas, Girala, Marcos, Juanola, Adria, Kim, Jeong Han, Kim, Tae Hun, Kumar, Pramod, Lattanzi, Barbara, Lee, Tae Hee, Rinaldi Lesmana, Cosmas A., Moreau, Richard, Nath, Preetam, Navarro, Gustavo, Park, Ji-Won, Pinero, Gisela, Pyrsopoulos, Nikolaos T., Restellini, Sophie, Romero, Gustavo, Sacco, Marco, Sevá-Pereira, Tiago, Simón-Talero, Macarena, Song, Do Seon, Suk, Ki Tae, Van Vlierberghe, Hans, Yim, Sun Young, Yoon, Eileen Laurel, Zaccherini, Giacomo, Piano, Salvatore, Singh, Virendra, Caraceni, Paolo, Maiwall, Rakhi, Alessandria, Carlo, Fernandez, Javier, Soares, Elza Cotrim, Kim, Dong Joon, Kim, Sung Eun, Marino, Monica, Vorobioff, Julio, Barea, Rita de Cassia Ribeiro, Merli, Manuela, Elkrief, Laure, Vargas, Victor, Krag, Aleksander, Singh, Shivaram Prasad, Lesmana, Laurentius Adrianto, Toledo, Claudio, Marciano, Sebastian, Verhelst, Xavier, Wong, Florence, Intagliata, Nicolas, Rabinowich, Liane, Colombato, Luis, Kim, Sang Gyune, Gerbes, Alexander, Durand, Francois, Roblero, Juan Pablo, Bhamidimarri, Kalyan Ram, Boyer, Thomas D., Maevskaya, Marina, Fassio, Eduardo, Kim, Hyoung Su, Hwang, Jae Seok, Gines, Pere, Gadano, Adrian, Sarin, Shiv Kumar, and Angeli, Paolo

Published
2019
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10. Determinants of clinical response to empirical antibiotic treatment in patients with cirrhosis and bacterial and fungal infections--Results from the ICA "Global Study" (EABCIR-Global Study).

Author

Maiwall, Rakhi, Piano, Salvatore, Singh, Virendra, Caraceni, Paolo, Alessandria, Carlo, Fernandez, Javier, Soares, Elza Cotrim, Dong Joon Kim, Sung Eun Kim, Marino, Monica, Vorobioff, Julio, Ribeiro Barea, Rita de Cassia, Merli, Manuela, Elkrief, Laure, Vargas, Victor, Krag, Aleksander, Singh, Shivaram Prasad, Lesmana, Laurentius Adrianto, Toledo, Claudio, and Marciano, Sebastian

Published
2024
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11. OP-4 DEVELOPMENT AND EXTERNAL VALIDATION OF A MODEL TO PREDICT MULTI-DRUG RESISTANT BACTERIAL INFECTIONS IN PATIENTS WITH CIRRHOSIS

Author

Marciano, Sebastian, Piano, Salvatore, Singh, Virendra, Caraceni, Paolo, Maiwall, Rakhi, Alessandria, Carlo, Fernandez, Javier, Kim, Dong Joon, Kim, Sung Eun, Soares, Elza, Marino, Monica, Vorobioff, Julio, Merli, Manuela, Elkrief, Laure, Vargas, Victor, Krag, Aleksander, Singh, Shivaram, Giunta, Diego, Elizondo, Martin, Anders, Maria Margarita, Dirchwolf, Melisa, Mendizabal, Manuel, Lesmana, Cosmas Rinaldi, Toledo, Claudio, Wong, Florence, Durand, Francois, Gadano, Adrian, and Angeli, Paolo

Published
2024
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14. Trends and cyclic variation in the incidence of childhood type 1 diabetes in two Italian regions over 33 years and during the COVID ‐19 pandemic

Author

Gesuita, Rosaria, primary, Rabbone, Ivana, additional, Marconi, Vittorio, additional, De Sanctis, Luisa, additional, Marino, Monica, additional, Tiberi, Valentina, additional, Iannilli, Antonio, additional, Tinti, Davide, additional, Favella, Lucia, additional, Giorda, Carlo, additional, Carle, Flavia, additional, and Cherubini, Valentino, additional

Published
2023
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16. Comment on 'Real-World Use of a New Hybrid Closed Loop Improves Glycemic Control in Youth with Type 1 Diabetes' by Messer et al

Author

Scaramuzza, Andrea Enzo, Bonfanti, Riccardo, Cherubini, Valentino, Marigliano, Marco, Schiaffini, Riccardo, Toni, Sonia, Rabbone, Ivana, Abate Daga, Federico, Bassi, Marta, Giulia Berioli, Maria, Bruzzi, Patrizia, Calandretti, Michela, Carducci, Chiara, Cavalli, Claudio, Delvecchio, Maurizio, Gesuita, Rosaria, Giorda, Sara, Iafusco, Dario, Lenzi, Lorenzo, Lombardo, Fortunato, Lo Presti, Donatella, Maffeis, Claudio, Maltoni, Giulio, Mameli, Chiara, Marino, Monica, Piccini, Barbara, Minuto, Nicola, Mozzillo, Enza, Piccinno, Elvira, Pignatiello, Ciro, Predieri, Barbara, Chiara Redaelli, Francesca, Rossella Ricciardi, Maria, Rigamonti, Andrea, Ripoli, Carlo, Maria Rosanio, Francesco, Salzano, Giuseppina, Savastio, Silvia, Tiberi, Valentina, Tinti, Davide, Trada, Michela, Zanetta, Sara, Zanfardino, Angela, Zucchini, Stefano, Scaramuzza, Andrea Enzo, Bonfanti, Riccardo, Cherubini, Valentino, Marigliano, Marco, Schiaffini, Riccardo, Toni, Sonia, Rabbone, Ivana, Abate Daga, Federico, Bassi, Marta, Giulia Berioli, Maria, Bruzzi, Patrizia, Calandretti, Michela, Carducci, Chiara, Cavalli, Claudio, Delvecchio, Maurizio, Gesuita, Rosaria, Giorda, Sara, Iafusco, Dario, Lenzi, Lorenzo, Lombardo, Fortunato, Lo Presti, Donatella, Maffeis, Claudio, Maltoni, Giulio, Mameli, Chiara, Marino, Monica, Piccini, Barbara, Minuto, Nicola, Mozzillo, Enza, Piccinno, Elvira, Pignatiello, Ciro, Predieri, Barbara, Chiara Redaelli, Francesca, Rossella Ricciardi, Maria, Rigamonti, Andrea, Ripoli, Carlo, Maria Rosanio, Francesco, Salzano, Giuseppina, Savastio, Silvia, Tiberi, Valentina, Tinti, Davide, Trada, Michela, Zanetta, Sara, Zanfardino, Angela, Zucchini, Stefano, vEC Study, Group, and Mozzillo, Enza.

Subjects
Virtual educational camp, Adolescent, Type 1 diabete, Endocrinology, Diabetes and Metabolism, Blood Glucose Self-Monitoring, Adolescents, Advanced hybrid closed loop, Children, Closed-loop control, Type 1 diabetes, Glycemic Control, Medical Laboratory Technology, Endocrinology, Diabetes Mellitus, Type 1, Insulin Infusion Systems, Diabetes Mellitus, Humans, Type 1
Abstract

We read with interest the article by Messer et al.1 reporting a significant increase in time in range (TIR, +9%, P

Published
2022

17. Significant and persistent improvements in time in range and positive emotions in children and adolescents with type 1 diabetes using a closed-loop control system after attending a virtual educational camp

Author

Rabbone, Ivana, Savastio, Silvia, Pigniatiello, Ciro, Carducci, Chiara, Berioli, Maria Giulia, Cherubini, Valentino, Lo Presti, Donatella, Maltoni, Giulio, Mameli, Chiara, Marigliano, Marco, Minuto, Nicola, Mozzillo, Enza, Piccinno, Elvira, Predieri, Barbara, Rigamonti, Andrea, Ripoli, Carlo, Schiaffini, Riccardo, Lombardo, Fortunato, Tinti, Davide, Toni, Sonia, Zanfardino, Angela, Scaramuzza, Andrea Enzo, BassiBassi, Marta, Bonfanti, Riccardo, Bruzzi, Patrizia, Delvecchio, Maurizio, Giorda, Sara, Iafusco, Dario, Salzano, Giuseppina, Maffeis, Claudio, Redaelli, Francesca Chiara, Marino, Monica, Piccini, Barbara, Ricciardi, Maria Rossella, Rosanio, Francesco Maria, Tiberi, Valentina, Trada, Michela, Zanetta, Sara, Zucchini, Stefano, Calandretti, Michela, Daga, Federico Abate, Gesuita, Rosaria, Cavalli, Claudio, Rabbone, Ivana, Savastio, Silvia, Pigniatiello, Ciro, Carducci, Chiara, Berioli, Maria Giulia, Cherubini, Valentino, Lo Presti, Donatella, Maltoni, Giulio, Mameli, Chiara, Marigliano, Marco, Minuto, Nicola, Mozzillo, Enza, Piccinno, Elvira, Predieri, Barbara, Rigamonti, Andrea, Ripoli, Carlo, Schiaffini, Riccardo, Lombardo, Fortunato, Tinti, Davide, Toni, Sonia, Zanfardino, Angela, Scaramuzza, Andrea Enzo, Bonfanti, Riccardo, Rabbone, I., Savastio, S., Pigniatiello, C., Carducci, C., Berioli, M. G., Cherubini, V., Lo Presti, D., Maltoni, G., Mameli, C., Marigliano, M., Minuto, N., Mozzillo, E., Piccinno, E., Predieri, B., Rigamonti, A., Ripoli, C., Schiaffini, R., Lombardo, F., Tinti, D., Toni, S., Zanfardino, A., Scaramuzza, A. E., Bassibassi, Marta, Bruzzi, Patrizia, Delvecchio, Maurizio, Giorda, Sara, Iafusco, Dario, Salzano, Giuseppina, Maffeis, Claudio, Redaelli, Francesca Chiara, Marino, Monica, Piccini, Barbara, Ricciardi, Maria Rossella, Rosanio, Francesco Maria, Tiberi, Valentina, Trada, Michela, Zanetta, Sara, Zucchini, Stefano, Calandretti, Michela, Daga, Federico Abate, Gesuita, Rosaria, and Cavalli, Claudio

Subjects
Blood Glucose, Virtual educational camp, Type 1 diabete, Adolescent, Endocrinology, Diabetes and Metabolism, Emotions, Adolescents, Advanced hybrid closed loop, Children, Closed-loop control, Type 1 diabetes, Blood Glucose Self-Monitoring, Child, Humans, Hypoglycemic Agents, Insulin, Insulin Infusion Systems, Diabetes Mellitus, Type 1, Endocrinology, Diabetes Mellitus, Internal Medicine, Emotion, General Medicine, Type 1
Abstract

Objective To evaluate the six-month impact of the advanced automated functions of a closed-loop control (CLC) system (Control-IQ) and a virtual educational camp (vEC) on emotions and time in range (TIR) of children and adolescents with type 1 diabetes. Methods Children and their parents participated in a three-day vEC. Clinical, glucose, and emotion data were evaluated before, just after, and six months after the vEC. Emotions were evaluated using adapted Plutchik's and Geneva Emotion Wheels. Results Forty-three children and adolescents (7–16 years) showed significant improvements in positive emotions immediately and six months after the vEC (67% and 65% vs 38%, p < 0.05, respectively), while mixed emotions were reduced (32% and 15% vs 61%, p < 0.05 and p < 0.001, respectively). The median percentage TIR increased from 64% (IQR 54–72) to 75% (IQR 70–82) with Control-IQ (p < 0.001) six months after the vEC. Conclusions Positive emotions (joy, serenity, and satisfaction) significantly improved while mixed emotions were significantly worse six months after the initiation of a CLC system (Control-IQ) and a vEC.

Published
2022

18. Corrigendum: The silent epidemic of diabetic ketoacidosis at diagnosis of type 1 diabetes in children and adolescents in italy during the covid-19 pandemic in 2020

Author

Cherubini, Valentino, primary, Marino, Monica, additional, Scaramuzza, Andrea E., additional, Tiberi, Valentina, additional, Bobbio, Adriana, additional, Delvecchio, Maurizio, additional, Piccinno, Elvira, additional, Ortolani, Federica, additional, Innaurato, Stefania, additional, Felappi, Barbara, additional, Gallo, Francesco, additional, Ripoli, Carlo, additional, Ricciardi, Maria Rossella, additional, Pascarella, Filomena, additional, Stamati, Filomena A., additional, Citriniti, Felice, additional, Arnaldi, Claudia, additional, Monti, Sara, additional, Graziani, Vanna, additional, De Berardinis, Fiorella, additional, Giannini, Cosimo, additional, Chiarelli, Francesco, additional, Zampolli, Maria, additional, De Marco, Rosaria, additional, Bracciolini, Giulia Patrizia, additional, Grosso, Caterina, additional, De Donno, Valeria, additional, Piccini, Barbara, additional, Toni, Sonia, additional, Coccioli, Susanna, additional, Cardinale, Giuliana, additional, Bassi, Marta, additional, Minuto, Nicola, additional, D’Annunzio, Giuseppe, additional, Maffeis, Claudio, additional, Marigliano, Marco, additional, Zanfardino, Angela, additional, Iafusco, Dario, additional, Rollato, Assunta S., additional, Piscopo, Alessia, additional, Curto, Stefano, additional, Lombardo, Fortunato, additional, Bombaci, Bruno, additional, Sordelli, Silvia, additional, Mameli, Chiara, additional, Macedoni, Maddalena, additional, Rigamonti, Andrea, additional, Bonfanti, Riccardo, additional, Frontino, Giulio, additional, Predieri, Barbara, additional, Bruzzi, Patrizia, additional, Mozzillo, Enza, additional, Rosanio, Francesco, additional, Franzese, Adriana, additional, Piredda, Gavina, additional, Cardella, Francesca, additional, Iovane, Brunella, additional, Calcaterra, Valeria, additional, Berioli, Maria Giulia, additional, Lasagni, Anna, additional, Pampanini, Valentina, additional, Patera, Patrizia Ippolita, additional, Schiaffini, Riccardo, additional, Rutigliano, Irene, additional, Meloni, Gianfranco, additional, De Sanctis, Luisa, additional, Tinti, Davide, additional, Trada, Michela, additional, Guerraggio, Lucia Paola, additional, Franceschi, Roberto, additional, Cauvin, Vittoria, additional, Tornese, Gianluca, additional, Franco, Francesca, additional, Musolino, Gianluca, additional, Maltoni, Giulio, additional, Talarico, Valentina, additional, Iannilli, Antonio, additional, Lenzi, Lorenzo, additional, Matteoli, Maria Cristina, additional, Pozzi, Erica, additional, Moretti, Carlo, additional, Zucchini, Stefano, additional, Rabbone, Ivana, additional, and Gesuita, Rosaria, additional

Published
2022
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20. The Silent Epidemic of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Children and Adolescents in Italy During the COVID-19 Pandemic in 2020

Author

Cherubini, Valentino, primary, Marino, Monica, additional, Scaramuzza, Andrea E., additional, Tiberi, Valentina, additional, Bobbio, Adriana, additional, Delvecchio, Maurizio, additional, Piccinno, Elvira, additional, Ortolani, Federica, additional, Innaurato, Stefania, additional, Felappi, Barbara, additional, Gallo, Francesco, additional, Ripoli, Carlo, additional, Ricciardi, Maria Rossella, additional, Pascarella, Filomena, additional, Stamati, Filomena A., additional, Citriniti, Felice, additional, Arnaldi, Claudia, additional, Monti, Sara, additional, Graziani, Vanna, additional, De Berardinis, Fiorella, additional, Giannini, Cosimo, additional, Chiarelli, Francesco, additional, Zampolli, Maria, additional, De Marco, Rosaria, additional, Bracciolini, Giulia Patrizia, additional, Grosso, Caterina, additional, De Donno, Valeria, additional, Piccini, Barbara, additional, Toni, Sonia, additional, Coccioli, Susanna, additional, Cardinale, Giuliana, additional, Bassi, Marta, additional, Minuto, Nicola, additional, D’Annunzio, Giuseppe, additional, Maffeis, Claudio, additional, Marigliano, Marco, additional, Zanfardino, Angela, additional, Iafusco, Dario, additional, Rollato, Assunta S., additional, Piscopo, Alessia, additional, Curto, Stefano, additional, Lombardo, Fortunato, additional, Bombaci, Bruno, additional, Sordelli, Silvia, additional, Mameli, Chiara, additional, Macedoni, Maddalena, additional, Rigamonti, Andrea, additional, Bonfanti, Riccardo, additional, Frontino, Giulio, additional, Predieri, Barbara, additional, Bruzzi, Patrizia, additional, Mozzillo, Enza, additional, Rosanio, Francesco, additional, Franzese, Adriana, additional, Piredda, Gavina, additional, Cardella, Francesca, additional, Iovane, Brunella, additional, Calcaterra, Valeria, additional, Berioli, Maria Giulia, additional, Lasagni, Anna, additional, Pampanini, Valentina, additional, Patera, Patrizia Ippolita, additional, Schiaffini, Riccardo, additional, Rutigliano, Irene, additional, Meloni, Gianfranco, additional, De Sanctis, Luisa, additional, Tinti, Davide, additional, Trada, Michela, additional, Guerraggio, Lucia Paola, additional, Franceschi, Roberto, additional, Cauvin, Vittoria, additional, Tornese, Gianluca, additional, Franco, Francesca, additional, Musolino, Gianluca, additional, Maltoni, Giulio, additional, Talarico, Valentina, additional, Iannilli, Antonio, additional, Lenzi, Lorenzo, additional, Matteoli, Maria Cristina, additional, Pozzi, Erica, additional, Moretti, Carlo, additional, Zucchini, Stefano, additional, Rabbone, Ivana, additional, and Gesuita, Rosaria, additional

Published
2022
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21. TOP-064-YI Impact of bacterial infections on kidney function and survival in patients with decompensated cirrhosis and acute kidney injury worldwide-analysis of the ICA-GLOBAL AKI study

Author

Juanola, Adrià, Patidar, Kavish, Thu Ma, Ann, Barone, Anna, Incicco, Simone, Kulkarni, Anand, Luis Pérez-Hernández, José, Wentworth, Brian, Asrani, Sumeet, Alessandria, Carlo, Abdelaaty Abdelkader, Nadia, Jun Wong, Yu, Xie, Qing, Pyrsopoulos, Nikolaos T., Kim, Sung-Eun, Fouad, Yasser, Torre, Aldo, Cerda Reyes, Eira, Diaz-Ferrer, Javier, Maiwall, Rakhi, Simonetto, Douglas, Papp, Maria, Orman, Eric, Perricone, Giovanni, Sole, Cristina, Lange, Christian M., Farias, Alberto, Pereira, Gustavo, Gadano, Adrian, Caraceni, Paolo, Weil-Verhoeven, Delphine, Verma, Nipun, Han Kim, Jeong, Vorobioff, Julio D., Cordova-Gallardo, Jacqueline, Ivashkin, Vladimir, Pablo Roblero, Juan, Maan, Raoel, Toledo, Claudio, Riggio, Oliviero, Fassio, Eduardo, Marino, Mónica, Nabilou, Puria, Vargas, Victor, Merli, Manuela, Lofego Goncalves, Luciana, Rabinowich, Liane, Krag, Aleksander, Balcar, Lorenz, Montes, Pedro, Mattos, Angelo Z., Bruns, Tony, Mohammed Nur, Abdulsemed, Laleman, Wim, Carrera Estupiñan, Enrique, Cecilia Cabrera, Maria, Girala, Marcos, Samant, Hrishikesh, Raevens, Sarah, Madaleno, Joao, Ray Kim, W., Pablo Arab, Juan, Presa, José, Noronha Ferreira, Carlos, Galante, Antonio, Francoz, Claire, Allegretti, Andrew S., Bart Takkenberg, R., Harputluoglu, Murat, Marciano, Sebastián, Kumar Sarin, Shiv, Ginès, Pere, Angeli, Paolo, Sola, Elsa, and Piano, Salvatore

Published
2024
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22. TOP-062 Global epidemiology of acute kidney injury in hospitalized patients with cirrhosis: the ICA-GLOBAL AKI study

Author

Patidar, Kavish, Thu Ma, Ann, Juanola, Adrià, Barone, Anna, Incicco, Simone, Kulkarni, Anand, Luis Pérez-Hernàndez, José, Wentworth, Brian, Asrani, Sumeet, Alessandria, Carlo, Abdelaaty Abdelkader, Nadia, Jun Wong, Yu, Xie, Qing, Pyrsopoulos, Nikolaos T., Kim, Sung-Eun, Fouad, Yasser, Torre, Aldo, Cerda Reyes, Eira, Diaz-Ferrer, Javier, Maiwall, Rakhi, Simonetto, Douglas, Papp, Maria, Orman, Eric, Perricone, Giovanni, Sole, Cristina, Lange, Christian M., Farias, Alberto, Pereira, Gustavo, Gadano, Adrian, Caraceni, Paolo, Thevenot, Thierry, Verma, Nipun, Han Kim, Jeong, Vorobioff, Julio D., Cordova-Gallardo, Jacqueline, Ivashkin, Vladimir, Pablo Roblero, Juan, Maan, Raoel, Toledo, Claudio, Riggio, Oliviero, Fassio, Eduardo, Marino, Monica, Nabilou, Puria, Vargas, Victor, Merli, Manuela, Lofego Goncalves, Luciana, Rabinowich, Liane, Krag, Aleksander, Balcar, Lorenz, Montes, Pedro, Mattos, Angelo Z., Bruns, Tony, Mohammed Nur, Abdulsemed, Laleman, Wim, Carrera Estupiñan, Enrique, Cecilia Cabrera, Maria, Girala, Marcos, Samant, Hrishikesh, Raevens, Sarah, Madaleno, Joao, Ray Kim, W., Pablo Arab, Juan, Presa, José, Noronha Ferreira, Carlos, Galante, Antonio, Allegretti, Andrew S., Bart Takkenberg, R., Harputluoglu, Murat, Marciano, Sebastián, Kumar Sarin, Shiv, Ginès, Pere, Durand, François, Angeli, Paolo, Solà, Elsa, and Piano, Salvatore

Published
2024
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23. OS-038-YI Real-world practice patterns on the use of terlipressin in patients with cirrhosis and acute kidney injury-results from the ICA-GLOBAL AKI study

Author

Ma, Ann Thu, Juanola, Adrià, Patidar, Kavish, Barone, Anna, Incicco, Simone, Kulkarni, Anand, Pérez-Hernández, José Luis, Wentworth, Brian, Asrani, Sumeet, Alessandria, Carlo, Abdelkader, Nadia Abdelaaty, Wong, Yu Jun, Xie, Qing, Pyrsopoulos, Nikolaos T., Kim, Sung-Eun, Fouad, Yasser, Torre, Aldo, Reyes, Eira Cerda, Diaz-Ferrer, Javier, Maiwall, Rakhi, Simonetto, Douglas, Papp, Maria, Orman, Eric, Perricone, Giovanni, Solé, Cristina, Lange, Christian M., Farias, Alberto, Pereira, Gustavo, Gadano, Adrian, Caraceni, Paolo, Thévenot, Thierry, Verma, Nipun, Kim, Jeong Han, Vorobioff, Julio D., Cordova-Gallardo, Jacqueline, Ivashkin, Vladimir, Roblero, Juan Pablo, Maan, Raoel, Toledo, Claudio, Riggio, Oliviero, Fassio, Eduardo, Marino, Mónica, Nabilou, Puria, Vargas, Victor, Merli, Manuela, Goncalves, Luciana Lofego, Rabinowich, Liane, Krag, Aleksander, Balcar, Lorenz, Montes, Pedro, Mattos, Angelo Z., Bruns, Tony, Nur, Abdulsemed Mohammed, Laleman, Wim, Estupiñan, Enrique Carrera, Cabrera, Maria Cecilia, Girala, Marcos, Samant, Hrishikesh, Raevens, Sarah, Madaleno, Joao, Kim, W. Ray, Arab, Juan Pablo, Presa, José, Ferreira, Carlos Noronha, Galante, Antonio, Roux, Olivier, Allegretti, Andrew S., Takkenberg, R. Bart, Harputluoglu, Murat, Marciano, Sebastián, Sarin, Shiv Kumar, Ginès, Pere, Angeli, Paolo, Solà, Elsa, and Piano, Salvatore

Published
2024
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24. A Risk Profile for Disordered Eating Behaviors in Adolescents with Type 1 Diabetes: A Latent Class Analysis Study.

Author

Boccolini, Giada, Marino, Monica, Tiberi, Valentina, Iannilli, Antonio, Landi, Giulia, Grandi, Silvana, Tossani, Eliana, and Cherubini, Valentino

Abstract

(1) Background: This multi-center study aimed to identify a risk profile for disordered eating behaviors (DEBs) in youth with type 1 diabetes (T1D) based on their dietary intake, lipid profile, body mass index (BMI-SDS), and glycometabolic control. (2) Methods: Adolescents aged 11 to 18 years from five centers across Italy were recruited. Lipid profile, HbA1c, BMI-SDS, and dietary intake data were collected. The risk for developing DEBs was assessed via the Diabetes Eating Problems Survey-R (DEPS-R) questionnaire. A latent class analysis (LCA) was performed using a person-centered approach. (3) Results: Overall, 148 participants aged 11–18 (12.1, ±3.34), 52% males with a mean diabetes duration of 7.2 (±3.4), were enrolled. Based on the results of the DEBS-R score, LCA allowed us to highlight two different classes of patients which were defined as "at-risk" and "not at-risk" for DEB. The risk profile for developing DEBs is characterized by higher BMI—SDS (23.9 vs. 18.6), higher HbA1c (7.9 vs. 7.1%), higher LDL cholesterol (99.9 vs. 88.8 mg/dL), lower HDL cholesterol (57.9 vs. 61.3 mg/dL), higher proteins (18.2 vs. 16.1%), and lower carbohydrates (43.9 vs. 45.3%). Adolescents included in the "at-risk" class were significantly older (p = 0.000), and their parents' SES was significantly lower (p = 0.041). (4) Conclusions: This study allowed us to characterize a risk profile for DEBs based on dietary behavior and clinical parameters. Early identification of the risk for DEBs allows timely intervention and prevention of behavior disorders. [ABSTRACT FROM AUTHOR]

Published
2023
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25. The Association between Treatment Modality, Lipid Profile, Metabolic Control in Children with Type 1 Diabetes and Celiac Disease—Data from the International Sweet Registry

Author

Marino, Monica, primary, Eckert, Alexander J., additional, Tell, Shoshana, additional, Krnic, Nevena, additional, Deja, Grazyna, additional, Faber Rasmussen, Vinni, additional, Coelho, Raquel, additional, Todorovic, Sladjana, additional, Jefferies, Craig A., additional, Sherif, Eman, additional, Martinez Mateu, Carolina, additional, and Elena Lionetti, Maria, additional

Published
2021
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27. Rethinking Carbohydrate Intake and Time in Range in Children and Adolescents with Type 1 Diabetes

Author

Cherubini, Valentino, primary, Marino, Monica, additional, Marigliano, Marco, additional, Maffeis, Claudio, additional, Zanfardino, Angela, additional, Rabbone, Ivana, additional, Giorda, Sara, additional, Schiaffini, Riccardo, additional, Lorubbio, Antonella, additional, Rollato, Serena, additional, Iannilli, Antonio, additional, Iafusco, Dario, additional, Scaramuzza, Andrea E., additional, Bowers, Renee, additional, and Gesuita, Rosaria, additional

Published
2021
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29. Differences between transient neonatal diabetes mellitus subtypes can guide diagnosis and therapy

Author

Bonfanti, Riccardo, primary, Iafusco, Dario, additional, Rabbone, Ivana, additional, Diedenhofen, Giacomo, additional, Bizzarri, Carla, additional, Patera, Patrizia Ippolita, additional, Reinstadler, Petra, additional, Costantino, Francesco, additional, Calcaterra, Valeria, additional, Iughetti, Lorenzo, additional, Savastio, Silvia, additional, Favia, Anna, additional, Cardella, Francesca, additional, Lo Presti, Donatella, additional, Girtler, Ylenia, additional, Rabbiosi, Sarah, additional, D’Annunzio, Giuseppe, additional, Zanfardino, Angela, additional, Piscopo, Alessia, additional, Casaburo, Francesca, additional, Pintomalli, Letizia, additional, Russo, Lucia, additional, Grasso, Valeria, additional, Minuto, Nicola, additional, Mucciolo, Mafalda, additional, Novelli, Antonio, additional, Marucci, Antonella, additional, Piccini, Barbara, additional, Toni, Sonia, additional, Silvestri, Francesca, additional, Carrera, Paola, additional, Rigamonti, Andrea, additional, Frontino, Giulio, additional, Trada, Michela, additional, Tinti, Davide, additional, Delvecchio, Maurizio, additional, Rapini, Novella, additional, Schiaffini, Riccardo, additional, Mammì, Corrado, additional, Barbetti, Fabrizio, additional, _, _, additional, Aloe, Monica, additional, Amadeo, Simona, additional, Arnaldi, Claudia, additional, Bassi, Marta, additional, Beccaria, Luciano, additional, Benelli, Marzia, additional, Maria Berioloi, Giulia, additional, Bertelli, Enrica, additional, Biagioni, Martina, additional, Bobbio, Adriana, additional, Boccato, Stefano, additional, Bologna, Oriana, additional, Bontempi, Franco, additional, Bonura, Clara, additional, Bracciolini, Giulia, additional, Brufani, Claudia, additional, Bruzzi, Patrizia, additional, Buono, Pietro, additional, Cardani, Roberta, additional, Cardinale, Giuliana, additional, Casertano, Alberto, additional, Cristina Castiglione, Maria, additional, Cauvin, Vittoria, additional, Cherubini, Valentino, additional, Chiarelli, Franco, additional, Chiari, Giovanni, additional, Cianfarani, Stefano, additional, Cirillo, Dante, additional, Citriniti, Felice, additional, Coccioli, Susanna, additional, Cogliardi, Anna, additional, Confetto, Santino, additional, Contreas, Giovanna, additional, Corò, Anna, additional, Corsini, Elisa, additional, Cresta, Nicoletta, additional, De Berardinis, Fiorella, additional, De Donno, Valeria, additional, De Filippo, Giampaolo, additional, De Marco, Rosaria, additional, Deodati, Annalisa, additional, Faleschini, Elena, additional, Fattorusso, Valentina, additional, Favalli, Valeria, additional, Felappi, Barbara, additional, Ferrito, Lucia, additional, Fichera, Graziella, additional, Fontana, Franco, additional, Fornari, Elena, additional, Franceschi, Roberto, additional, Franco, Francesca, additional, Franzese, Adriana, additional, Paola Frongia, Anna, additional, Gaiero, Alberto, additional, Gallo, Francesco, additional, Gargantini, Luigi, additional, Giani, Elisa, additional, Giorgetti, Chiara, additional, Bianchi, Giulia, additional, Graziani, Vanna, additional, Gualtieri, Antonella, additional, Guasti, Monica, additional, Iannicelli, Gennaro, additional, Iannilli, Antonio, additional, Giovanna, Ignaccolo, additional, Ingletto, Dario, additional, Innaurato, Stefania, additional, Inzaghi, Elena, additional, Iovane, Brunella, additional, Kaufmann, Peter, additional, La Loggia, Alfonso, additional, Lapolla, Rosa, additional, Lasagni, Anna, additional, Lazzaro, Nicola, additional, Lenzi, Lorenzo, additional, Lera, Riccardo, additional, Levantini, Gabriella, additional, Lombardo, Fortunato, additional, Lonero, Antonella, additional, Longhi, Silvia, additional, Lucchesi, Sonia, additional, Paola Guerraggio, Lucia, additional, Lucieri, Sergio, additional, Macellaro, Patrizia, additional, Maffeis, Claudio, additional, Mainetti, Bendetta, additional, Maltoni, Giulio, additional, Mameli, Chiara, additional, Mammì, Francesco, additional, Luisa Manca-Bitti, Maria, additional, Manco, Melania, additional, Marino, Monica, additional, Mariano, Matteo, additional, Marigliano, Marco, additional, Marsciani, Alberto, additional, Mastrangelo, Costanzo, additional, Cristina Matteoli, Maria, additional, Mazzali, Elena, additional, Meschi, Franco, additional, MIgliaccio, Antonella, additional, Morandi, Anita, additional, Morganti, Gianfranco, additional, Mozzillo, Enza, additional, Musolino, Gianluca, additional, Nugnes, Rosa, additional, Ortolani, Federica, additional, Pardi, Daniela, additional, Pascarella, Filomena, additional, Passanisi, Stefano, additional, Pedini, Annalisa, additional, Pennati, Cristina, additional, Perrotta, Angelo, additional, Peruzzi, Sonia, additional, Peverelli, Paola, additional, Pezzino, Giulia, additional, Claudia Piona, Anita, additional, Piredda, Gavina, additional, Pistone, Carmelo, additional, Prandi, Elena, additional, Pedieri, Barbara, additional, Di Bonito, Procolo, additional, Pulcina, Anna, additional, Quinci, Maria, additional, Randazzo, Emioli, additional, Ricciardi, Rossella, additional, Ripoli, Carlo, additional, Roppolo, Rosanna, additional, Rutigliano, Irene, additional, Sabbio, Alberto, additional, salardi, Silvana, additional, Salvatoni, Alessandro, additional, Saporiti, Anna, additional, Sardi, Rita, additional, Scanu, Mariapiera, additional, Scaramuzza, Andrea, additional, Eleonardo Schiven, ,, additional, Secco, Andrea, additional, Sessa, Linda, additional, Sogno Valin, Paola, additional, Sordelli, Silvia, additional, Spallino, Luisa, additional, Stagi, Stefano, additional, Stamati, Filomena, additional, Suprani, Tosca, additional, Talarico, Valentina, additional, Timapanaro, Tiziana, additional, Tirendi, Antonella, additional, Tomaselli, Letizia, additional, Tornese, Gianluca, additional, Andrea Trettene, Adolfo, additional, Tumini, Stefano, additional, Valerio, Giuliana, additional, Ventrici, Claudia, additional, Viscardi, Matteo, additional, Zaffani, Silvana, additional, Zampolli, Maria, additional, Zanette, Giorgio, additional, Zecchino, Clara, additional, Antonietta Zedda, Maria, additional, Zonca, Silvia, additional, and Zucchini, Stefano, additional

Published
2021
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30. Clinical features and evolution of bacterial infection-related acute-on-chronic liver failure

Author

Wong, Florence, primary, Piano, Salvatore, additional, Singh, Virendra, additional, Bartoletti, Michele, additional, Maiwall, Rakhi, additional, Alessandria, Carlo, additional, Fernandez, Javier, additional, Soares, Elza Cotrim, additional, Kim, Dong Joon, additional, Kim, Sung Eun, additional, Marino, Monica, additional, Vorobioff, Julio, additional, Barea, Rita de Cassia Ribeiro, additional, Merli, Manuela, additional, Elkrief, Laure, additional, Vargas, Victor, additional, Krag, Aleksander, additional, Singh, Shivaram Prasad, additional, Lesmana, Laurentius Adrianto, additional, Toledo, Claudio, additional, Marciano, Sebastian, additional, Verhelst, Xavier, additional, Intagliata, Nicolas, additional, Rabinowich, Liane, additional, Colombato, Luis, additional, Kim, Sang Gyune, additional, Gerbes, Alexander, additional, Durand, Francois, additional, Roblero, Juan Pablo, additional, Bruns, Tony, additional, Yoon, Eileen Laurel, additional, Girala, Marcos, additional, Pyrsopoulos, Nikolaos T., additional, Kim, Tae Hun, additional, Yim, Sun Young, additional, Juanola, Adria, additional, Gadano, Adrian, additional, Angeli, Paolo, additional, Bhamidimarri, Kalyan, additional, Boyer, Thomas D., additional, Brodersen, Carlos, additional, Campion, Daniela, additional, Caraceni, Paolo, additional, de Man, Robert A., additional, Fassio, Eduardo, additional, Fialla, Annette Dam, additional, Gambino, Carmine, additional, Gautam, Vikas, additional, Gines, Pere, additional, Hwang, Jae Seok, additional, Kim, Hyoung Su, additional, Kim, Jeong Han, additional, Kumar, Pramod, additional, Lattanz, Barbara, additional, Lee, Tae Hee, additional, Rinaldi Lesmana, Cosmas A., additional, Maevskaya, Marina, additional, Nath, Preetam, additional, Navarro, Gustavo, additional, Park, Ji-Won, additional, Pinero, Gisela, additional, Restellini, Sophie, additional, Romero, Gustavo, additional, Sevá -Pereira, Tiago, additional, Simón-Talero, Macarena, additional, Song, Do Seon, additional, Suk, Ki Tae, additional, Van Vlierberghe, Hans, additional, and Zaccherini, Giacomo, additional

Published
2021
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31. WED-348 - Development and external validation of a model to predict multi-drug resistant bacterial infections in patients with cirrhosis

Author

Marciano, Sebastián, Piano, Salvatore, Singh, Virendra, Caraceni, Paolo, Maiwall, Rakhi, Alessandria, Carlo, Fernandez, Javier, Kim, Dong Joon, Kim, Sung-Eun, Soares, Elza, Marino, Mónica, Vorobioff, Julio, Merli, Manuela, Elkrief, Laure, Vargas Blasco, Víctor Manuel, Krag, Aleksander, Singh, Shivaram, Giunta, Diego, Elizondo, Martín, Anders, Maria Margarita, dirchwolf, melisa, Mendizabal, Manuel, Lesmana, Rinaldi, Toledo, Claudio, Wong, Florence, Durand, François, Gadano, Adrian, and Angeli, Paolo

Published
2023
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32. Activation of Sulfolobus solfataricus alcohol dehydrogenase by modification of cysteine residue 38 with iodoacetic acid

Author

Raia, Carlo A., Caruso, Carla, Marino, Monica, Vespa, Nunzia, and Rossi, Mose

Subjects
Alcohol dehydrogenase -- Research, Enzymes -- Structure-activity relationship, Biological sciences, Chemistry
Abstract

A study was conducted to determine the effect of iodoacetate on Sulfolobus solfataricus-derived alcohol dehydrogenase (SsADH). The results show that carboxymethylation of the catalytic site increased the benzyl alcohol oxidation activity, thermostability and thermophilicity of SsADH. Carboxymethylation enhances the oxidative activity of SsADH by increasing the rate of dissociation of modified SsADH-NADH complex which is the rate-limiting step for native SsADH.

Published
1996

33. Effectiveness of a closed‐loop control system and a virtual educational camp for children and adolescents with type 1 diabetes: A prospective, multicentre, real‐life study.

Author

Cherubini, Valentino, Rabbone, Ivana, Berioli, Maria Giulia, Giorda, Sara, Lo Presti, Donatella, Maltoni, Giulio, Mameli, Chiara, Marigliano, Marco, Marino, Monica, Minuto, Nicola, Mozzillo, Enza, Piccinno, Elvira, Predieri, Barbara, Ripoli, Carlo, Schiaffini, Riccardo, Rigamonti, Andrea, Salzano, Giuseppina, Tinti, Davide, Toni, Sonia, and Zanfardino, Angela

Subjects
TYPE 1 diabetes, CLOSED loop systems, TEENAGERS, CAMPS for children, INSULIN pumps, CONCENTRATION camps
Abstract

Aim: To evaluate the impact of a virtual educational camp (vEC) on glucose control in children and adolescents with type 1 diabetes using a closed‐loop control (CLC) system. Materials and Methods: This was a prospective multicentre study of children and adolescents with type 1 diabetes using the Tandem Basal‐IQ system. Insulin pumps were upgraded to Control‐IQ, and children and their parents participated in a 3‐day multidisciplinary vEC. Clinical data, glucose metrics and HbA1c were evaluated over the 12 weeks prior to the Control‐IQ update and over the 12 weeks after the vEC. Results: Forty‐three children and adolescents (aged 7‐16 years) with type 1 diabetes and their families participated in the vEC. The median percentage of time in target range (70‐180 mg/dL; TIR) increased from 64% (interquartile range [IQR] 56%‐73%) with Basal‐IQ to 76% (IQR 71%‐81%) with Control‐IQ (P <.001). After the vEC, more than 75% of participants achieved a TIR of more than 70%. The percentage of time between 180 and 250 mg/dL and above 250 mg/dL decreased by 5% (P <.01) and 6% (P <.01), respectively, while the time between 70 and 54 mg/dL and below 54 mg/dL remained low and unaltered. HbA1c decreased by 0.5% (P <.01). There were no episodes of diabetic ketoacidosis or severe hypoglycaemia. Conclusions: In this study of children managing their diabetes in a real‐world setting, more than 75% of children who participated in a vEC after starting a CLC system could obtain and maintain a TIR of more than 70%. The vEC was feasible and resulted in a significant and persistent improvement in TIR in children and adolescents with type 1 diabetes. [ABSTRACT FROM AUTHOR]

Published
2021
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35. Weekend-Based Parent-Group Intervention to Reduce Stress in Parents of Children and Adolescents with Type 1 Diabetes: A Pilot Study

Author

Ferrito, Lucia, primary, Predieri, Barbara, additional, Pjetraj, Dorina, additional, Alessandrelli, Maria Cristina, additional, Pagnini, Manuela, additional, Iannilli, Antonio, additional, Marino, Monica, additional, Tombolini, Stefano, additional, Pintaudi, Basilio, additional, Lucisano, Giuseppe, additional, Zani, Fabiana, additional, Iughetti, Lorenzo, additional, Nicolucci, Antonio, additional, and Cherubini, Valentino, additional

Published
2019
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36. Epidemiology and Effects of Bacterial Infections in Patients With Cirrhosis Worldwide

Author

Piano, Salvatore, primary, Singh, Virendra, additional, Caraceni, Paolo, additional, Maiwall, Rakhi, additional, Alessandria, Carlo, additional, Fernandez, Javier, additional, Soares, Elza Cotrim, additional, Kim, Dong Joon, additional, Kim, Sung Eun, additional, Marino, Monica, additional, Vorobioff, Julio, additional, Barea, Rita de Cassia Ribeiro, additional, Merli, Manuela, additional, Elkrief, Laure, additional, Vargas, Victor, additional, Krag, Aleksander, additional, Singh, Shivaram Prasad, additional, Lesmana, Laurentius Adrianto, additional, Toledo, Claudio, additional, Marciano, Sebastian, additional, Verhelst, Xavier, additional, Wong, Florence, additional, Intagliata, Nicolas, additional, Rabinowich, Liane, additional, Colombato, Luis, additional, Kim, Sang Gyune, additional, Gerbes, Alexander, additional, Durand, Francois, additional, Roblero, Juan Pablo, additional, Bhamidimarri, Kalyan Ram, additional, Boyer, Thomas D., additional, Maevskaya, Marina, additional, Fassio, Eduardo, additional, Kim, Hyoung Su, additional, Hwang, Jae Seok, additional, Gines, Pere, additional, Gadano, Adrian, additional, Sarin, Shiv Kumar, additional, Angeli, Paolo, additional, Bartoletti, Michele, additional, Brodersen, Carlos, additional, Bruns, Tony, additional, de Man, Robert A., additional, Fialla, Annette Dam, additional, Gambino, Carmine, additional, Gautam, Vikas, additional, Girala, Marcos, additional, Juanola, Adria, additional, Kim, Jeong Han, additional, Kim, Tae Hun, additional, Kumar, Pramod, additional, Lattanzi, Barbara, additional, Lee, Tae Hee, additional, Rinaldi Lesmana, Cosmas A., additional, Moreau, Richard, additional, Nath, Preetam, additional, Navarro, Gustavo, additional, Park, Ji-Won, additional, Pinero, Gisela, additional, Pyrsopoulos, Nikolaos T., additional, Restellini, Sophie, additional, Romero, Gustavo, additional, Sacco, Marco, additional, Sevá-Pereira, Tiago, additional, Simón-Talero, Macarena, additional, Song, Do Seon, additional, Suk, Ki Tae, additional, Van Vlierberghe, Hans, additional, Yim, Sun Young, additional, Yoon, Eileen Laurel, additional, and Zaccherini, Giacomo, additional

Published
2019
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41. 1349-P: Sociodemographic and Clinical Factors Associate with Parental Fear of Hypoglycemia: Italian Nationwide Cross-Sectional Survey.

Author

CHERUBINI, VALENTINO, PJETRAJ, DORINA, BONFANTI, RICCARDO, MARINO, MONICA, IANNILLI, ANTONIO, CARLE, FLAVIA, and GESUITA, ROSARIA

Abstract

Aim of this study was to evaluate the association of socio-demographic and clinical factors, including technologies used for diabetes management, and parental fear of hypoglycaemia (FOH) in parents of children (<18y) with T1D. A cross-sectional, nationwide electronic survey, supported by the Italian Society of Paediatric Endocrinology and Family Associations of children with diabetes, was conducted during September-November 2018. The Hypoglycaemia Fear Survey for Parents (HFS-P), a 25-item questionnaire, was used to assess FOH. Quintile regression analysis was performed to estimate factors associated to FOH. Out of 1450 questionnaires, 1106 (873 mothers) reported a complete HFS-P in both the worry and behavior subscales. Children median age was 11 y (IQR: 8-14), median diabetes duration 6 y (IQR: 3-10); median HbA1c 7.2% (IQR: 6.7-7.8). Glucose Sensor (including CGM and FGM) was used in 79% of patients and insulin pump in 45%. Median HFS-P worry score was 36 (IQR: 29-46), behavior score 29 (IQR: 24-33). Parental FOH was associated with parental modifiable and non-modifiable factors (Table 1). The use of insulin pump does not seem to impact worries and behaviors, while glucose sensor do influence parental behaviors. As the use of diabetes-advanced technologies is today increasingly widespread, the impact on parental FOH requires more analyses. Disclosure: V. Cherubini: None. D. Pjetraj: None. R. Bonfanti: Advisory Panel; Self; Abbott, Lilly Diabetes, Medtronic, Novo Nordisk A/S, Roche Diabetes Care, Sanofi. M. Marino: None. A. Iannilli: None. F. Carle: None. R. Gesuita: None. [ABSTRACT FROM AUTHOR]

Published
2019
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42. Our Readers Write.

Author

Sturtz, Pam, Portlock, Jessica, Schoettley, Kelly, Bush, Alicia, Marino, Monica, Bruening, Amy, O'Leary, Patricia, Hooks, Judy, and Perez, Anita

Subjects
TEACHERS, ACTIVITY programs in education, POETRY (Literary form), FRACTIONS, DIVISION
Abstract

Offers advice from several teachers in the U.S. on educational activities about various topics. Poetry; Fractions; Long division.

Published
2004

43. The Silent Epidemic of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Children and Adolescents in Italy During the COVID-19 Pandemic in 2020

Author

Valentino Cherubini, Monica Marino, Andrea E. Scaramuzza, Valentina Tiberi, Adriana Bobbio, Maurizio Delvecchio, Elvira Piccinno, Federica Ortolani, Stefania Innaurato, Barbara Felappi, Francesco Gallo, Carlo Ripoli, Maria Rossella Ricciardi, Filomena Pascarella, Filomena A. Stamati, Felice Citriniti, Claudia Arnaldi, Sara Monti, Vanna Graziani, Fiorella De Berardinis, Cosimo Giannini, Francesco Chiarelli, Maria Zampolli, Rosaria De Marco, Giulia Patrizia Bracciolini, Caterina Grosso, Valeria De Donno, Barbara Piccini, Sonia Toni, Susanna Coccioli, Giuliana Cardinale, Marta Bassi, Nicola Minuto, Giuseppe D’Annunzio, Claudio Maffeis, Marco Marigliano, Angela Zanfardino, Dario Iafusco, Assunta S. Rollato, Alessia Piscopo, Stefano Curto, Fortunato Lombardo, Bruno Bombaci, Silvia Sordelli, Chiara Mameli, Maddalena Macedoni, Andrea Rigamonti, Riccardo Bonfanti, Giulio Frontino, Barbara Predieri, Patrizia Bruzzi, Enza Mozzillo, Francesco Rosanio, Adriana Franzese, Gavina Piredda, Francesca Cardella, Brunella Iovane, Valeria Calcaterra, Maria Giulia Berioli, Anna Lasagni, Valentina Pampanini, Patrizia Ippolita Patera, Riccardo Schiaffini, Irene Rutigliano, Gianfranco Meloni, Luisa De Sanctis, Davide Tinti, Michela Trada, Lucia Paola Guerraggio, Roberto Franceschi, Vittoria Cauvin, Gianluca Tornese, Francesca Franco, Gianluca Musolino, Giulio Maltoni, Valentina Talarico, Antonio Iannilli, Lorenzo Lenzi, Maria Cristina Matteoli, Erica Pozzi, Carlo Moretti, Stefano Zucchini, Ivana Rabbone, Rosaria Gesuita, Cherubini, Valentino, Marino, Monica, Scaramuzza, Andrea E, Tiberi, Valentina, Bobbio, Adriana, Delvecchio, Maurizio, Piccinno, Elvira, Ortolani, Federica, Innaurato, Stefania, Felappi, Barbara, Gallo, Francesco, Ripoli, Carlo, Ricciardi, Maria Rossella, Pascarella, Filomena, Stamati, Filomena A, Citriniti, Felice, Arnaldi, Claudia, Monti, Sara, Graziani, Vanna, De Berardinis, Fiorella, Giannini, Cosimo, Chiarelli, Francesco, Zampolli, Maria, De Marco, Rosaria, Bracciolini, Giulia Patrizia, Grosso, Caterina, De Donno, Valeria, Piccini, Barbara, Toni, Sonia, Coccioli, Susanna, Cardinale, Giuliana, Bassi, Marta, Minuto, Nicola, D'Annunzio, Giuseppe, Maffeis, Claudio, Marigliano, Marco, Zanfardino, Angela, Iafusco, Dario, Rollato, Assunta S, Piscopo, Alessia, Curto, Stefano, Lombardo, Fortunato, Bombaci, Bruno, Sordelli, Silvia, Mameli, Chiara, Macedoni, Maddalena, Rigamonti, Andrea, Bonfanti, Riccardo, Frontino, Giulio, Predieri, Barbara, Bruzzi, Patrizia, Mozzillo, Enza, Rosanio, Francesco, Franzese, Adriana, Piredda, Gavina, Cardella, Francesca, Iovane, Brunella, Calcaterra, Valeria, Berioli, Maria Giulia, Lasagni, Anna, Pampanini, Valentina, Patera, Patrizia Ippolita, Schiaffini, Riccardo, Rutigliano, Irene, Meloni, Gianfranco, De Sanctis, Luisa, Tinti, Davide, Trada, Michela, Guerraggio, Lucia Paola, Franceschi, Roberto, Cauvin, Vittoria, Tornese, Gianluca, Franco, Francesca, Musolino, Gianluca, Maltoni, Giulio, Talarico, Valentina, Iannilli, Antonio, Lenzi, Lorenzo, Matteoli, Maria Cristina, Pozzi, Erica, Moretti, Carlo, Zucchini, Stefano, Rabbone, Ivana, and Gesuita, Rosaria

Subjects
COVID - 19, Adolescent, type 1 diabetes, Endocrinology, Diabetes and Metabolism, Longitudinal Studie, Diabetic Ketoacidosis, socioeconomic status, DKA, Diabetes Mellitus, Humans, Longitudinal Studies, Child, Pandemics, Settore MED/38 - Pediatria Generale e Specialistica, Pandemic, type 1 diabete, Incidence, COVID-19, diabetes onset, Communicable Disease Control, Italy, Diabetes Mellitus, Type 1, socioeconomic statu, Human, Type 1
Abstract

Aim/HypothesisTo compare the frequency of diabetic ketoacidosis (DKA) at diagnosis of type 1 diabetes in Italy during the COVID-19 pandemic in 2020 with the frequency of DKA during 2017-2019.MethodsForty-seven pediatric diabetes centers caring for >90% of young people with diabetes in Italy recruited 4,237 newly diagnosed children with type 1 diabetes between 2017 and 2020 in a longitudinal study. Four subperiods in 2020 were defined based on government-imposed containment measures for COVID-19, and the frequencies of DKA and severe DKA compared with the same periods in 2017-2019.ResultsOverall, the frequency of DKA increased from 35.7% (95%CI, 33.5-36.9) in 2017-2019 to 39.6% (95%CI, 36.7-42.4) in 2020 (p=0.008), while the frequency of severe DKA increased from 10.4% in 2017-2019 (95%CI, 9.4-11.5) to 14.2% in 2020 (95%CI, 12.3-16.4, pConclusions/InterpretationThere was an increase in the frequency of DKA and severe DKA in children newly diagnosed with type 1 diabetes during the COVID-19 pandemic in 2020, with no apparent association with the severity of COVID-19 infection severity or containment measures. There has been a silent outbreak of DKA in children during the pandemic, and preventive action is required to prevent this phenomenon in the event of further generalized lockdowns or future outbreaks.

Published
2022

44. [Risk factors in post partum depression].

Author

Marino M, Battaglia E, Massimino M, and Aguglia E

Subjects
Depression, Postpartum psychology, Female, Hormones physiology, Humans, Risk Factors, Depression, Postpartum epidemiology
Abstract

It is commonly believed that pregnancy is a time of good mental health. However it has been observed, until recently, that many pregnant women, above all in post partum period, manifest depressive symptoms like sadness, social withdrawal and lack of motivation. The consequences are enormous, for mother mental health and for the psychical development of the baby. It becomes therefore necessary to screening and to precociously intervene on these pathological conditions and thanks also to the suitable knowledge of the risk factors for the potential development of depression post partum.

Published
2012
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