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The paper proposes to present the way through which the neutral treatment method influences the performance indicators of an electrical energy distribution service. In the paper are presented both the calculation methods for all indicators as well as their evolution using as reference two different electric stations pertaining to Distribuţie Energie Oltenia (DEO), stations which during 2017 have had their neutral treatment method changed. The indicators regarding the quality of the transport and distribution service, as well as the quality of the electric energy distributed through the electrical transport network (RET) and the electrical distribution network (RED) represent an essential factor in the substantiation of the technical and economic elements related to the execution/ modernization of the electric networks and influence greatly the economic efficiency of the users’ activity. In the category of users of the electric networks are included the consumers of electric energy, the distribution operator, the producers and other network operators connected to the networks of the national electrical system (SEN).

In our study, we define the linear backward in time problem for a thermoelastic body with a dipolar structure. In our first main result, we prove the uniqueness of the solution for this problem. Afterward, the issue of locating solutions of the backward in time problem in time will be approached as a consequence of the uniqueness result. In fact, we address the question of the impossibility of locating the solution of this problem in time.

Glycosylated α-dystroglycan provides an essential link between extracellular matrix proteins, like laminin, and the cellular cytoskeleton via the dystrophin-glycoprotein complex. In secondary dystroglycanopathy muscular dystrophy, glycosylation abnormalities disrupt a complex O-mannose glycan necessary for muscle structural integrity and signaling. Fktn-deficient dystroglycanopathy mice develop moderate to severe muscular dystrophy with skeletal muscle developmental and/or regeneration defects. To gain insight into the role of glycosylated α-dystroglycan in these processes, we performed muscle fiber typing in young (2, 4 and 8 week old) and regenerated muscle. In mice with Fktn disruption during skeletal muscle specification (Myf5/Fktn KO), newly regenerated fibers (embryonic myosin heavy chain positive) peaked at 4 weeks old, while total regenerated fibers (centrally nucleated) were highest at 8 weeks old in tibialis anterior (TA) and iliopsoas, indicating peak degeneration/regeneration activity around 4 weeks of age. In contrast, mature fiber type specification at 2, 4 and 8 weeks old was relatively unchanged. Fourteen days after necrotic toxin-induced injury, there was a divergence in muscle fiber types between Myf5/Fktn KO (skeletal-muscle specific) and whole animal knockout induced with tamoxifen post-development (Tam/Fktn KO) despite equivalent time after gene deletion. Notably, Tam/Fktn KO retained higher levels of embryonic myosin heavy chain expression after injury, suggesting a delay or abnormality in differentiation programs. In mature fiber type specification post-injury, there were significant interactions between genotype and toxin parameters for type 1, 2a, and 2x fibers, and a difference between Myf5/Fktn and Tam/Fktn study groups in type 2b fibers. These data suggest that functionally glycosylated α-dystroglycan has a unique role in muscle regeneration and may influence fiber type specification post-injury.

We describe the genetic code in terms of numbers that help us to find several dual symmetries. Our formulation can even be rewritten regarding the up-down and right-left dual concepts. We argue that our work may bring many topological tools to studying the DNA molecule, including the Grassmann-Plucker coordinates, which are important in mathematical and physical contexts. [ABSTRACT FROM AUTHOR]

The Carpathians and other mountainous regions around the world are renowned for their specific landscapes shaped by pastoralism, a millennia-old traditional and sustainable economic system. In Romania, this traditional occupation has an established place within the Romanian culture. In an environment where large predators are present, the livestock owners and shepherds have traditionally relied, and still do, on livestock guardian dogs (LGDs) to protect the flock against carnivores or theft, therefore, the dogs are perceived as an integral component of the traditional pastoral system. However, from late April until the end of September, many outdoor recreational activities like hiking, mountain trail running, or biking overlap with the pastoral calendar, creating a potential for conflict between two, very different categories of landscape users, with recurring incidents happening over the years. In this study, a winter GPS monitoring campaign was proposed, between November 2023 and January 2024 that used GPS professional collars to track the movements of two livestock guardian dogs stationed at two sheepfolds located at their winter bases in the hills at the foot of Ignis Mountains (part of the Romanian northern Carpathians) from northwestern Maramureș Land, Romania. The campaign generated point-based spatiotemporal data processed and analyzed in M. Excel and QGIS using Kernel density estimation as the main method to generate metrics and identify potential clusters of LGD activity in their usual environment. The results highlight high observational clusters near the winter folds but also lower observational clusters in areas situated hundreds of meters distance around the main compound, in certain locations. Although temporally limited, the results have the potential to help the understanding of the animal's preferred zone of habitation and substantiate future win-win cohabitation solutions that minimize conflictual encounters between the shepherds and their guardian dogs on one side, as primary land users, and outdoor recreationists as other landscape users.