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Your search keyword '"Mariga, Abigail"' showing total 13 results
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13 results on '"Mariga, Abigail"'

1. Contributors

Author

Antony, Irene, primary, Buttermore, Elizabeth D., additional, Cappuccio, Gerarda, additional, Casabona, Juan Cruz, additional, Chapman, Gareth, additional, Chen, Ivy Pin-Fang, additional, Chou, Harue, additional, Daheron, Laurence, additional, Dei-Ampeh, Alfred K., additional, Durcan, Thomas M., additional, Engle, Sandra J., additional, Faloon, Patrick, additional, FitzGerald, Kevin T., additional, French, Deborah L., additional, Giordano, James, additional, Glass, Madison R., additional, Kaushik, Komal, additional, Kleiman, Robin J., additional, Klein Gunnewiek, Teun, additional, Kroll, Kristen L., additional, Kyere, Felix A., additional, Lachman, Herbert M., additional, Latour, Brooke, additional, Maletic-Savatic, Mirjana, additional, Mao, Xiaobo, additional, Mariga, Abigail, additional, Maussion, Gilles, additional, Meganathan, Kesavan, additional, Mishra, Swati, additional, Nadif Kasri, Nael, additional, Petersen, Andrew, additional, Pimentel, Luisa, additional, Prakasam, Ramachandran, additional, Robert, Aiko, additional, Rocha, Cecilia, additional, Shah, Manuj, additional, Stein, Jason L., additional, Sundberg, Maria, additional, Van Der Kant, Rik, additional, Van Deursen, Coen, additional, Waxman, Elisa A., additional, Wu, Samantha, additional, Ying, Mingyao, additional, Young, Damian W., additional, and Young, Jessica E., additional

Published
2023
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8. Neurotrophin signalling: novel insights into mechanisms and pathophysiology.

Author

Mitre, Mariela, Mariga, Abigail, and Chao, Moses V.

Abstract

Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are prominent regulators of neuronal survival, growth and differentiation during development. While trophic factors are viewed as well-understood but not innovative molecules, there are many lines of evidence indicating that BDNF plays an important role in the pathophysiology of many neurodegenerative disorders, depression, anxiety and other psychiatric disorders. In particular, lower levels of BDNF are associated with the aetiology of Alzheimer’s and Huntington’s diseases. A major challenge is to explain how neurotrophins are able to induce plasticity, improve learning and memory and prevent age-dependent cognitive decline through receptor signalling. This article will review the mechanism of action of neurotrophins and how BDNF/tropomyosin receptor kinase B (TrkB) receptor signaling can dictate trophic responses and change brain plasticity through activity-dependent stimulation. Alternative approaches for modulating BDNF/TrkB signalling to deliver relevant clinical outcomes in neurodegenerative and neuropsychiatric disorders will also be described. [ABSTRACT FROM AUTHOR]

Published
2017
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11. Robust changes in expression of brain-derived neurotrophic factor (BDNF) mRNA and protein across the brain do not translate to detectable changes in BDNF levels in CSF or plasma

Author

Lanz, Thomas A., primary, Bove, Susan E., additional, Pilsmaker, Catherine D., additional, Mariga, Abigail, additional, Drummond, Elena M., additional, Cadelina, Gregory W., additional, Adamowicz, Wendy O., additional, Swetter, Brentt J., additional, Carmel, Sharon, additional, Dumin, Jo Ann, additional, and Kleiman, Robin J., additional

Published
2012
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12. P3‐380: Dendritic spine density deficits in the hippocampal CA1 region of young Tg2576 mice are ameliorated with the PDE9A inhibitor PF‐04447943

Author

Kleiman, Robin J., primary, Lanz, Thomas A., additional, Finley, James E., additional, Bove, Susan E., additional, Majchrzak, Mark J., additional, Becker, Stacey L., additional, Carvajal-Gonzales, Santos, additional, Kuhn, A. Max, additional, Wood, Kathleen M., additional, Mariga, Abigail, additional, Nelson, Frederick R., additional, Verhoest, Patrick R., additional, Seymour, Patricia A., additional, and Stephenson, Diane T., additional

Published
2010
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