6 results on '"Maria Maputle"'
Search Results
2. The impact of DNA methylation as a factor of Adverse Pregnancy and Birth Outcomes (APBOs): a systematic review protocol
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Innocent Moagi, Lawrence Mabasa, Sonto Maria Maputle, Duduzile Ndwandwe, Ndidzulafhi Selina Raliphaswa, Lizzy Mutshinyalo Netshikweta, Thivhulawi Malwela, and Amidou Samie
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Epigenetics ,DNA methylation ,Preterm birth (PTB) ,Low birth weight (LBW) ,Sepsis ,Adverse pregnancy outcomes ,Medicine - Abstract
Abstract Background Deoxyribonucleic acid (DNA) methylation is one of the epigenetic modifications that has gained a lot of interest as a factor influencing fetal programming and as a biomarker for adverse pregnancy and birth outcomes (APBOs). Epidemiological studies have demonstrated that DNA methylation can result in adverse pregnancy and birth outcomes (APBOs) including miscarriage, intrauterine growth restriction (IUGR), low birth weight (LBW), sepsis, and preterm birth (PTB), which may later result in diseases in adulthood. However, the mechanism by which DNA methylation influences these APBOs remains unclear. The systematic review will assess the association between global and gene-specific DNA methylation with adverse pregnancy outcomes. Method The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020 checklist will be followed when conducting this systematic review. To develop the search strategy the PI(E)COS (population, intervention/exposure, comparator/control, outcome, and study designs) framework will be followed. Thus far, the research team has retrieved 4721 from Cochrane Library, PubMed, Web of Sciences, and MEDLINE. Out of these, 584 studies have been screened for eligibility, and approximately 124 studies meet the inclusion criteria. Pending the search results identified from the grey literature. For identification of unpublished studies in journals indexed in electronic databases, Google Scholar will be used. I.M and A.S will separately extract data from the articles and screen them, if there are any disagreements between I.M and A.S, then the L.M will resolve them. The methodological quality and bias risk of the included studies will be evaluated using the Critical Appraisal Skill Programme CASP) checklist. $${I}^{2}$$ I 2 and $$\chi 2{}$$ χ 2 alpha = 0.10 statistic will be used for assessing statistical heterogeneity between studies. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach will be used to assess and grade the overall quality of extracted data. Ethics and dissemination Ethical approval is not required. The systematic review will assess available literature on possible associations between DNA methylation with adverse pregnancy and birth outcomes (APBOs) including LBW, IUGR, miscarriage, sepsis, and PTB. The findings could help guide future research assessing DNA methylation and other APBOs. Systematic review registration PROSPERO CRCRD42022370647.
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- 2024
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3. Factors facilitating trained NIMART nurses’ adherence to treatment guidelines: a vital matter in the management of TB/HIV treatment in South Africa
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Lufuno Makhado, Mashudu Davhana-Maselesele, Rachel Tsakani Lebese, and Sonto Maria Maputle
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Adherence ,NIMART ,NIMART-trained nurses ,TB/HIV ,Treatment guidelines ,Nursing ,RT1-120 - Abstract
Abstract Background Globally, the burden of tuberculosis or human immunodeficiency virus (TB/HIV) is at 24% and this alarming rate compelled the World Health Organization (WHO) to declare the African region as a critical workforce shortage area. To facilitate adherence to treatment guidelines, WHO recommended a strategy of task shifting for countries with high health workforce shortages. The strategy aimed at the redistribution of health care tasks to available workers. The study aimed to determine the factors facilitating nurse-initiated management of antiretroviral therapy (NIMART) trained nurses’ adherence to TB/HIV treatment guidelines. Methods The study employed an exploratory-descriptive design. The study was conducted in Ugu and Ngaka Modiri Molema Districts of KwaZulu-Natal (KZN) and North West (NW) Provinces of South Africa. The population comprised of 24 participants who were purposively selected. The in-depth focus group discussions were conducted and ATLAS T.I. was used for data analysis following the basic steps of notice-collect-think (NCT) analysis. Trustworthiness and adherence to ethics were ensured. Results The singular theme of factors facilitating NIMART trained nurses’ adherence to treatment guidelines which included positive attitudinal needs and positive behavioural change emerged from raw data. Conclusion Continuous training, support supervision, and improved relationships with colleagues need to be enhanced to enable NIMART trained nurses to adhere to treatment guidelines.
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- 2020
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4. Mentorship during transition period: a challenge for newly qualified midwives in Limpopo province of South Africa
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Khathutshelo Simane-Netshisaulu, Maria Maputle, Lizzy Mutshinyalo Netshikweta, and Hilda Shilubane
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ComputingMilieux_GENERAL ,South Africa ,ComputingMilieux_THECOMPUTINGPROFESSION ,Pregnancy ,education ,Mentors ,Humans ,Female ,General Medicine ,Workload ,Midwifery ,Experienced midwives ,mentoring ,mentor ,newly qualified midwives ,Qualitative Research - Abstract
Background: Mentorship is a process in which structured support is provided to new graduates of the profession to facilitate theireffective transitional journey to professional autonomy. Objectives: To explore and describe the mentoring process as experienced by newly qualified midwives and experienced midwivesduring thetransition period. Methods: Aqualitative approach was used. Five hospitals were selected from Limpopo province. The study was conducted in a maternity unit of each selected hospital. Population comprised of all newly qualified midwives as well as all experienced midwives working at institutions under study. Non-probability, purposive sampling method was used to select twenty-five newly qualified and twenty-five experienced midwives working in maternity wards of selected hospitals. In-depth face-to-face interviews were conducted for data collection. Results: Ineffective mentoring processes were reported, where only a few experienced midwives seemed ready to provide informal and unstructured support to graduates. Experienced midwives recognised their mentoring role however, felt they did not have sufficient knowledge and skills regarding mentoring process. Shortage of staff and increased workload were reported as challenges which negatively affected the mentoring process. Conclusion: Mentoring is an effective process for facilitation of graduates’ transition process to become registered autonomous midwifery practitioners. However, they were not effectively mentored; consequently, negatively affecting their development to professional maturity. Keywords: Experienced midwives; mentoring; mentor; newly qualified midwives.
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- 2022
5. Analysis of HIV/AIDS Integration into the Academic Curriculum at a Selected University in South Africa
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Tinotenda Murwira Success, Mamotema M. Peta, Khoza Lunic Base, Jabu Tsakani Mabunda, and Sonto Maria Maputle
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Community and Home Care ,Medical education ,Health (social science) ,Higher education ,business.industry ,05 social sciences ,Public Health, Environmental and Occupational Health ,medicine.disease ,Syllabus ,03 medical and health sciences ,0302 clinical medicine ,Acquired immunodeficiency syndrome (AIDS) ,0502 economics and business ,medicine ,030212 general & internal medicine ,Psychology ,business ,Curriculum ,050203 business & management - Abstract
Background:Although there is evidence that education is a social weapon in the fight against HIV/AIDS, there is also evidence that, to date, HIV/AIDS is not fully integrated into all the disciplines in Higher Education Institutions (HEIs). Therefore, most of the university students in South Africa are not well prepared to be HIV/AIDS-competent graduates who can live and work in a society ravaged by AIDS.Objective:This study sought to analyse the extent of HIV/AIDS integration into the curricula in various departments at a selected university in the Limpopo Province, South Africa.Materials and Methods:The study used quantitative and qualitative approaches to analyse the extent of HIV/AIDS integration into the curricula. The curriculum calendars were retrieved from the university website. An audit tool guided retrieval of HIV/AIDS content and was analysed using SPSS V 25. The qualitative content analysis was used to describe the nature of HIV/AIDS content.Results:Out of eight schools, about 68 modules had HIV/AIDS content. The majority of the modules (53; 78%) were offered at the undergraduate level. Furthermore, the majority of the HIV/AIDS content (62; 91%) was integrated into undergraduate compulsory modules. Most (34; 51%) of the HIV/AIDS content were located in health sciences disciplines. HIV/AIDS content was mostly integrated into existing carrier modules. Time allocation for the teaching of HIV/AIDS was not indicated. Most of the modules did have information about teaching and assessment strategies.Conclusion:It is recommended that discipline-specific HIV/AIDS content be integrated into all disciplines.
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- 2020
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6. Usage of Implant Contraceptive Method by Sexually Active Women: An Exploration of The Factors Contributing To Implant Contraceptive Method Uptake in Vhembe District, Limpopo Province, South Africa
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Rhulani Caroline Shihundla, Rachel Tsakani Lebese, and Sonto Maria Maputle
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Background The estimation of unmet contraceptive needs triggered the National Department of Health in South Africa to introduced the Implant contraceptive method in 2014 to increase the range of contraceptive options for sexually active women. Implant contraceptive uptake remains low in the Vhembe District despite its effectiveness in preventing unintended pregnancy. Very little is known about the factors that affect the usage of this cost-effective device. Aim To explore sexually active women's knowledge, practices and attitudes related to the usage of the Implant contraceptive method in Vhembe District, Limpopo Province. Methods The study was qualitative, explorative, descriptive and contextual, conducted using a non-probability purposive technique to sample 62 sexually active women aged from 18–45 years. The sample size was determined by data saturation. Five (5) focus group discussions were conducted using semi-structured interviews, which lasted for 45–60 minutes. Tesch's eight steps of open coding were used to analyse data. Results Results revealed that sexually active women experience some challenges related to Implant Contraceptive Method. The majority of women had little knowledge about the device, making it difficult for them to use the method. The majority of sexually active women indicated that they are interested in the method and would like to enjoy the benefits. Conclusion Sexually active women's intentions to utilise the Implant contraceptive method was very low as the majority of them had a negative attitude towards the method, due to insufficient knowledge. Professional nurses should inform women and public members about newly introduced Implant contraceptive method at Primary Health Care facilities to enhance usage.
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- 2021
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