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1. Fourth universal definition of myocardial infarction (2018)

Author

Fausto J. Pinto, Russell V. Luepker, Maria Angeles Alonso Garcia, Pascal Vranckx, James L. Januzzi, Alexander R. Lyon, S. Richard Underwood, Filippo Crea, Bertil Lindahl, Raymond J. Gibbons, Allan S. Jaffe, Sidney C. Smith, Joseph S. Alpert, Don Cutlip, Bernard R. Chaitman, P. J. Devereaux, P. Gabriel Steg, John M. Canty, Chiara Bucciarelli-Ducci, Harvey D. White, Rose Marie Robertson, Patrick T. O'Gara, Hugo A. Katus, David A. Morrow, J.L. Zamorano, Frans Van de Werf, Renu Virmani, Kristian Thygesen, Keith A. A Fox, William S. Weintraub, Christian Hamm, Dan Atar, Hans Mickley, Rafelle De Caterina, Fred S. Apple, Elliott M. Antman, Jeroen J. Bax, L. Kristin Newby, and Robert O. Bonow

Subjects
Male, medicine.medical_specialty, Cardiac troponin, business.industry, Cardiology, Myocardial Infarction, MEDLINE, 030204 cardiovascular system & hematology, medicine.disease, United States, Europe, 03 medical and health sciences, 0302 clinical medicine, 030220 oncology & carcinogenesis, Internal medicine, medicine, Humans, Female, Myocardial infarction, Myocardial infarction diagnosis, Cardiology and Cardiovascular Medicine, business, Societies, Medical
Published
2018
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2. Fourth universal definition of myocardial infarction (2018)

Author

Thygesen, Kristian, Alpert, Joseph S., Jaffe, Allan S., Chaitman, Bernard R., Bax, Jeroen J., Morrow, David A., White, Harvey D., Mickley, Hans, Crea, Filippo, Van De Werf, Frans, Bucciarelli-Ducci, Chiara, Katus, Hugo A., Pinto, Fausto J., Antman, Elliott M., Hamm, Christian W., De Caterina, Raffaele, Januzzi, James L., Apple, Fred S., Garcia, Maria Angeles Alonso, Underwood, S. Richard, Canty, John M., Lyon, Alexander R., Devereaux, P. J., Zamorano, Jose Luis, Lindahl, Bertil, Weintraub, William S., Newby, L. Kristin, Virmani, Renu, Vranckx, Pascal, Cutlip, Don, Gibbons, Raymond J., Smith, Sidney C., Atar, Dan, Luepker, Russell V., Robertson, Rose Marie, Bonow, Robert O., Steg, P. Gabriel, O’Gara, Patrick T., Fox, Keith A. A., Hasdai, David, Aboyans, Victor, Achenbach, Stephan, Agewall, Stefan, Alexander, Thomas, Avezum, Alvaro, Barbato, Emanuele, Bassand, Jean-Pierre, Bates, Eric, Bittl, John A., Breithardt, Güenter, Bueno, Héctor, Bugiardini, Raffaele, Cohen, Mauricio G., Dangas, George, De Lemos, James A., Delgado, Victoria, Filippatos, Gerasimos, Fry, Edward, Granger, Christopher B., Halvorsen, Sigrun, Hlatky, Mark A., Ibanez, Borja, James, Stefan, Kastrati, Adnan, Leclercq, Christophe, Mahaffey, Kenneth W., Mehta, Laxmi, Müller, Christian, Patrono, Carlo, Piepoli, Massimo Francesco, Piñeiro, Daniel, Roffi, Marco, Rubboli, Andrea, Sharma, Samin, Simpson, Iain A., Tendera, Michael, Valgimigli, Marco, Van Der Wal, Allard C., Windecker, Stephan, Thygesen, Kristian, Alpert, Joseph S., Jaffe, Allan S., Chaitman, Bernard R., Bax, Jeroen J., Morrow, David A., White, Harvey D., Mickley, Han, Crea, Filippo, Van De Werf, Fran, Bucciarelli-Ducci, Chiara, Katus, Hugo A., Pinto, Fausto J., Antman, Elliott M., Hamm, Christian W., De Caterina, Raffaele, Januzzi, James L., Apple, Fred S., Garcia, Maria Angeles Alonso, Underwood, S. Richard, Canty, John M., Lyon, Alexander R., Devereaux, P.J., Zamorano, Jose Lui, Lindahl, Bertil, Weintraub, William S., Newby, L. Kristin, Virmani, Renu, Vranckx, Pascal, Cutlip, Don, Gibbons, Raymond J., Smith, Sidney C., Atar, Dan, Luepker, Russell V., Robertson, Rose Marie, Bonow, Robert O., Steg, P. Gabriel, O’Gara, Patrick T., Fox, Keith A. A., Hasdai, David, Aboyans, Victor, Achenbach, Stephan, Agewall, Stefan, Alexander, Thoma, Avezum, Alvaro, Barbato, Emanuele, Bassand, Jean-Pierre, Bates, Eric, Bittl, John A., Breithardt, Güenter, Bueno, Héctor, Bugiardini, Raffaele, Cohen, Mauricio G., Dangas, George, De Lemos, James A., Delgado, Victoria, Filippatos, Gerasimo, Fry, Edward, Granger, Christopher B., Halvorsen, Sigrun, Hlatky, Mark A., Ibanez, Borja, James, Stefan, Kastrati, Adnan, Leclercq, Christophe, Mahaffey, Kenneth W., Mehta, Laxmi, Müller, Christian, Patrono, Carlo, Piepoli, Massimo Francesco, Piñeiro, Daniel, Roffi, Marco, Rubboli, Andrea, Sharma, Samin, Simpson, Iain A., Tendera, Michael, Valgimigli, Marco, Van Der Wal, Allard C., Windecker, Stephan, and Cardiology

Subjects
CHRONIC KIDNEY-DISEASE, Type 5 MI, Cardiac & Cardiovascular Systems, END-POINT DEFINITIONS, Epidemiology, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Infarction, 030204 cardiovascular system & hematology, Type 1 MI, ACUTE CORONARY SYNDROME, Severity of Illness Index, Electrocardiography, High sensitivity cardiac troponin, 0302 clinical medicine, Silent Myocardial Infarction, Medicine, 030212 general & internal medicine, Myocardial infarction, Coronary Artery Bypass, Re-infarction, Type 4c MI, 1102 Cardiorespiratory Medicine and Haematology, Type 2 MI, Troponin, RULE-OUT STRATEGIES, ST-SEGMENT-ELEVATION, Silent myocardial infarction, Myocardial infarction with non-obstructive coronary arteries (MINOCA), Recurrent myocardial infarction, CARDIOVASCULAR MAGNETIC-RESONANCE, Myocardial injury, Practice Guidelines as Topic, Cardiology, Cardiac troponin, Kidney Diseases, Type 4b MI, Takotsubo syndrome, Cardiology and Cardiovascular Medicine, Life Sciences & Biomedicine, BUNDLE-BRANCH BLOCK, Diagnostic Imaging, Acute coronary syndrome, medicine.medical_specialty, Consensus, Type 3 MI, JOINT EUROPEAN-SOCIETY, Coronary Restenosis, Cardiac procedural myocardial injury, Expert Consensus Document, Prior myocardial infarction, Type 4a MI, 03 medical and health sciences, Percutaneous Coronary Intervention, Takotsubo Cardiomyopathy, Terminology as Topic, Physiology (medical), Internal medicine, Humans, Heart Failure, Community and Home Care, Science & Technology, Bundle branch block, business.industry, LONG-TERM MORTALITY, Congresses as Topic, medicine.disease, Cardiovascular System & Hematology, ESC Scientific Document Group, Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, SENSITIVITY CARDIAC TROPONIN, Cardiovascular System & Cardiology, Long term mortality, business, Biomarkers
Abstract

Kristian Thygesen∗ (Denmark) Joseph S. Alpert∗ (USA) Allan S. Jaffe (USA) Bernard R. Chaitman (USA) Jeroen J. Bax (The Netherlands) David A. Morrow (USA) Harvey D. White∗ (New Zealand) Hans Mickley (Denmark) Filippo Crea (Italy) Frans Van de Werf (Belgium) Chiara Bucciarelli-Ducci (

Published
2019
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3. New medicinal products for chronic heart failure: advances in clinical trial design and efficacy assessment

Author

Stuart J. Pocock, Alexander R. Lyon, Daniel M. Bloomfield, Amany El-Gazayerly, Claudio Gimpelewicz, Faiez Zannad, Piotr Ponikowski, Warren Sherman, Fady I. Malik, Wendy Gattis Stough, Marco Metra, Anna Baczynska, Krishna Prasad, Karsten Bruins Slot, Caroline Boulton, Jose Lopez-Sendon, Pieter A. de Graeff, Maureen Cronin, Ian Laws, Isabelle Richard-Lordereau, Benoit Tyl, Karl Swedberg, Stefan D. Anker, Salim Janmohamed, Gerasimos Filippatos, Martin R. Cowie, Lothar Roessig, Heidi Janssen, Santiago Figueroa Perez, Martin Lefkowitz, Pieter A. Doevendans, Marc A. Pfeffer, Giuseppe M.C. Rosano, Narimon Honarpour, Maria Borentain, Albert M. Kim, Maria Angeles Alonso Garcia, John J.V. McMurray, and Dominik Lautsch

Subjects
medicine.medical_specialty, Pathology, business.industry, Clinical study design, Alternative medicine, Health technology, Guideline, 030204 cardiovascular system & hematology, 3. Good health, Clinical trial, 03 medical and health sciences, 0302 clinical medicine, Quality of life (healthcare), Cardiovascular agent, medicine, Life expectancy, 030212 general & internal medicine, Cardiology and Cardiovascular Medicine, Intensive care medicine, business
Abstract

Despite the availability of a number of different classes of therapeutic agents with proven efficacy in heart failure, the clinical course of heart failure patients is characterized by a reduction in life expectancy, a progressive decline in health-related quality of life and functional status, as well as a high risk of hospitalization. New approaches are needed to address the unmet medical needs of this patient population. The European Medicines Agency (EMA) is undertaking a revision of its Guideline on Clinical Investigation of Medicinal Products for the Treatment of Chronic Heart Failure. The draft version of the Guideline was released for public consultation in January 2016. The Cardiovascular Round Table of the European Society of Cardiology (ESC), in partnership with the Heart Failure Association of the ESC, convened a dedicated two-day workshop to discuss three main topic areas of major interest in the field and addressed in this draft EMA guideline: (i) assessment of efficacy (i.e. endpoint selection and statistical analysis); (ii) clinical trial design (i.e. issues pertaining to patient population, optimal medical therapy, run-in period); and (iii) research approaches for testing novel therapeutic principles (i.e. cell therapy). This paper summarizes the key outputs from the workshop, reviews areas of expert consensus, and identifies gaps that require further research or discussion. Collaboration between regulators, industry, clinical trialists, cardiologists, health technology assessment bodies, payers, and patient organizations is critical to address the ongoing challenge of heart failure and to ensure the development and market access of new therapeutics in a scientifically robust, practical and safe way.

Published
2017
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4. GUIDELINES ON THE MANAGEMENT OF STABLE ANGINA PECTORIS (ENDING)

Author

Jean Marco, Paweł Buszman, F. Crea, G. De Backer, Jose Lopez-Sendon, Caroline Daly, P. Hjenmdahl, Paolo G. Camici, Maria Angeles Alonso Garcia, Udo Sechtem, João Morais, Keith A.A. Fox, Kristian Thygesen, John Pepper, D. Ardissimo, and M. L. Simoons

Subjects
medicine.medical_specialty, lcsh:Diseases of the circulatory (Cardiovascular) system, business.industry, Task force, lcsh:RM1-950, RM1-950, Stable angina, lcsh:Therapeutics. Pharmacology, lcsh:RC666-701, RC666-701, Physical therapy, medicine, Diseases of the circulatory (Cardiovascular) system, Pharmacology (medical), Therapeutics. Pharmacology, Cardiology and Cardiovascular Medicine, business
Abstract

The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology

Published
2015

5. New approaches to hyperkalemia in patients with indications for renin angiotensin aldosterone inhibitors: Considerations for trial design and regulatory approval

Author

Mikhail Kosiborod, Maria Angeles Alonso Garcia, Norman Stockbridge, Henrik S. Rasmussen, Javed Butler, Aliza Thompson, Bertram Pitt, Murray Epstein, Lance Berman, Alexandre Mebazaa, Faiez Zannad, George L. Bakris, Janet Wittes, Patrick Rossignol, Luis M. Ruilope, Wendy Gattis Stough, Centre d'investigation clinique [Nancy] (CIC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Défaillance Cardiovasculaire Aiguë et Chronique (DCAC), Cardiovascular and Renal Clinical Trialists [Vandoeuvre-les-Nancy] (INI-CRCT), Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy], Association Lorraine pour le Traitement de l'Insuffisance Rénale (ALTIR), College of Pharmacy and Health Sciences [Campbell University], Campbell University College, University of Miami Leonard M. Miller School of Medicine (UMMSM), Scientific Advice Working Party European Medicines Agency, Imperial College Healthcare Trust, London, UK, The University of Chicago Medicine [Chicago], Stony Brook University [SUNY] (SBU), State University of New York (SUNY), Saint Luke's Mid America Heart Institute, University of Missouri [Kansas City] (UMKC), University of Missouri System, Relypsa, Biomarqueurs CArdioNeuroVASCulaires (BioCANVAS), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service d'Anesthésie-Réanimation [AP-HP Hôpitaux Saint-Louis Lariboisière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), ZS Pharma, Inc., Institute of Investigation and Hypertension Unit [Madrid], Hospital Universitario 12 de Octubre [Madrid], U.S. Food and Drug Administration (FDA), Statistics Collaborative, Inc., University of Michigan Medical School, University of Michigan [Ann Arbor], University of Michigan System-University of Michigan System, CIC-Nancy, Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy]-Institut National de la Santé et de la Recherche Médicale (INSERM), and Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Lariboisière-Université Paris Diderot - Paris 7 (UPD7)

Subjects
medicine.medical_specialty, Hyperkalemia, MESH: Clinical Trials as Topic, Polymers, Heart failure, MESH: Comorbidity, Angiotensin-Converting Enzyme Inhibitors, Comorbidity, 030204 cardiovascular system & hematology, Renin-Angiotensin System, 03 medical and health sciences, 0302 clinical medicine, MESH: Practice Guidelines as Topic, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, MESH: Renin-Angiotensin System, Diabetes mellitus, Internal medicine, Renin–angiotensin system, medicine, Humans, 030212 general & internal medicine, Dosing, Chronic, Renal insufficiency, Intensive care medicine, Clinical Trials as Topic, MESH: Humans, business.industry, Clinical study design, MESH: Research Design, MESH: Angiotensin-Converting Enzyme Inhibitors, nutritional and metabolic diseases, medicine.disease, 3. Good health, Endocrinology, Tolerability, Research Design, MESH: Potassium, Practice Guidelines as Topic, Potassium, MESH: Hyperkalemia, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Kidney disease
Abstract

International audience; Hyperkalemia is a common clinical problem, especially in patients with chronic kidney disease, diabetes mellitus, or heart failure. Treatment with renin angiotensin aldosterone system inhibitors exacerbates the risk of hyperkalemia in these patients. Concern about hyperkalemia can result in the failure to initiate, suboptimal dosing, or discontinuation of renin angiotensin aldosterone system inhibitor therapy in patients; effective treatments for hyperkalemia might mitigate such undertreatment. New treatments for hyperkalemia in development may offer better efficacy, tolerability and safety profiles than do existing approved treatments. These compounds might enable more eligible patients to receive renin angiotensin aldosterone system inhibitor therapy or to receive renin angiotensin aldosterone system inhibitors at target doses. The evidence needed to support a treatment claim (reduction in serum potassium) differs from that needed to support a prevention claim (preventing hyperkalemia to allow renin angiotensin aldosterone system inhibitor treatment). Thus, several issues related to clinical trial design and drug development need to be considered. This paper summarizes and expands upon a discussion at the Global Cardiovascular Clinical Trialists 2014 Forum and examines methodologic considerations for trials of new potassium binders for the prevention and management of hyperkalemia in patients with renin angiotensin aldosterone system inhibitor indications.

Published
2016
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6. Assessment of cardiovascular risk of new drugs for the treatment of diabetes mellitus: risk assessment vs. risk aversion

Author

Bart Van der Schueren, André Scheen, Ofri Mosenzon, Harald Sourij, Peter A. McCullough, Wolfgang Koenig, Faiez Zannad, Raymond J. Lipicky, Maria Angeles Alonso Garcia, Jeffrey S. Borer, Samy Hadjadj, Juan Tamargo, Gonzalo Calvo, Stuart J. Pocock, George L. Bakris, Wendy Gattis Stough, Stuart Kupfer, Christina Stahre, and William B. White

Subjects
Drug, medicine.medical_specialty, media_common.quotation_subject, Reviews, Guidelines as Topic, Disease, 030204 cardiovascular system & hematology, Placebo, Risk Assessment, 03 medical and health sciences, Hope, 0302 clinical medicine, Diabetes mellitus, medicine, Diabetes Mellitus, Animals, Hypoglycemic Agents, Humans, Pharmacology (medical), 030212 general & internal medicine, European Union, Diabetes mellitus risk, Intensive care medicine, Drug Approval, media_common, Risk Management, Plants, Medicinal, Risk aversion, business.industry, United States Food and Drug Administration, Type 2 Diabetes Mellitus, medicine.disease, Legislation, Drug, United States, Clinical trial, Treatment Outcome, Diabetes Mellitus, Type 2, Cardiovascular Diseases, Cardiology and Cardiovascular Medicine, business, Licensure, Phytotherapy
Abstract

The Food and Drug Administration issued guidance for evaluating the cardiovascular risk of new diabetes mellitus drugs in 2008. Accumulating evidence from several completed trials conducted within this framework raises questions as to whether requiring safety outcome studies for all new diabetes mellitus therapies remains justified. Given the burden of cardiovascular disease in patients with diabetes, the focus should shift towards cardiovascular outcome studies designed to evaluate efficacy (i.e. to determine the efficacy of a drug over placebo or standard care) rather than demonstrating that risk is not increased by a pre-specified safety margin. All stakeholders are responsible for ensuring that new drug approvals occur under conditions of appropriate safety and effectiveness. It is also a shared responsibility to avoid unnecessary hurdles that may compromise access to useful drugs and threaten the sustainability of health systems. It is critical to renew this debate so that stakeholders can collectively determine the optimal approach for developing new drugs to treat type 2 diabetes mellitus.

Published
2016

7. Guía sobre el manejo de la angina estable. Versión resumida

Author

Maarten L. Simoons, Diego Ardissino, Kim Fox, Guy De Backer, Filippo Crea, Jose Lopez-Sendon, Kristian Thygesen, John Pepper, João Morais, Maria Angeles Alonso Garcia, Paul Hjemdahl, Paolo G. Camici, Jean Marco, Udo Sechtem, Caroline Daly, and Paweł Buszman

Subjects
business.industry, Medicine and Health Sciences, Medicine, Cardiology and Cardiovascular Medicine, business, Humanities
Published
2006
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8. Executive summary of the guidelines on the diagnosis and treatment of acute heart failure: The Task Force on Acute Heart Failure of the European Society of Cardiology

Author

Markku S, Nieminen, Michael, Böhm, Martin R, Cowie, Helmut, Drexler, Gerasimos S, Filippatos, Guillaume, Jondeau, Yonathan, Hasin, José, Lopez-Sendon, Alexandre, Mebazaa, Marco, Metra, Andrew, Rhodes, Karl, Swedberg, Silvia G, Priori, Maria Angeles Alonso, Garcia, Jean-Jacques, Blanc, Andrzej, Budaj, Veronica, Dean, Jaap, Deckers, Enrique Fernandez, Burgos, John, Lekakis, Bertil, Lindahl, Gianfranco, Mazzotta, João, Morais, Ali, Oto, Otto A, Smiseth, Kenneth, Dickstein, Anibal, Albuquerque, Pedro, Conthe, Maria, Crespo-Leiro, Roberto, Ferrari, Ferenc, Follath, Antonello, Gavazzi, Uwe, Janssens, Michel, Komajda, Rui, Moreno, Mervyn, Singer, Satish, Singh, Michal, Tendera, and Kristian, Thygesen

Subjects
medicine.medical_specialty, Cardiotonic Agents, Process (engineering), Vasodilator Agents, media_common.quotation_subject, MEDLINE, Angiotensin-Converting Enzyme Inhibitors, Task (project management), Risk Factors, Internal medicine, medicine, Humans, Quality (business), Diuretics, Monitoring, Physiologic, media_common, Heart Failure, Executive summary, Task force, business.industry, Hemodynamics, Guideline, Clinical Practice, Acute Disease, Cardiology, Heart Transplantation, Heart-Assist Devices, Cardiology and Cardiovascular Medicine, business
Abstract

Guidelines and Expert Consensus documents aim to present all the relevant evidence on a particular issue in order to help physicians to weigh the benefits and risks of a particular diagnostic or therapeutic procedure. They should be helpful in everyday clinical decision-making. A great number of Guidelines and Expert Consensus Documents have been issued in recent years by the European Society of Cardiology (ESC) and by different organizations and other related societies. This profusion can put at stake the authority and validity of guidelines, which can only be guaranteed if they have been developed by an unquestionable decision-making process. This is one of the reasons why the ESC and others have issued recommendations for formulating and issuing Guidelines and Expert Consensus Documents. In spite of the fact that standards for issuing good quality Guidelines and Expert Consensus Documents are well defined, recent surveys of Guidelines and Expert Consensus Documents published in peer-reviewed journals between 1985 and 1998 have shown that methodological standards were not complied with in the vast majority of cases. It is therefore of great importance that guidelines and recommendations are presented in formats that are easily interpreted. Subsequently, their implementation programmes must also be well conducted. Attempts have been made to determine whether guidelines improve the quality of clinical practice and the utilization of health resources. The ESC Committee for Practice Guidelines (CPG) supervises and coordinates the preparation of new Guidelines and Expert Consensus Documents produced by Task Forces, expert groups or consensus panels. The chosen experts in these writing panels are asked to provide disclosure statements of all relationships they may have which might be perceived as real or potential conflicts of interest. These disclosure forms are kept on file at the European Heart House, headquarters of the ESC. The Committee is also responsible for the …

Published
2005
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9. Documento de Consenso de Expertos sobre el uso de inhibidores de la enzima de conversión de la angiotensina en la enfermedad cardiovascular

Author

Ali Oto, Martin R. Cowie, Jaap W. Deckers, Lars Køber, Giuseppe Mancia, Carina Blomström-Lundqvist, Bertil Lindahl, Gianfranco Mazzotta, Otto A. Smiseth, Roberto Ferrari, Keith A.A. Fox, Keith McGregor, Enrique Fernandez Burgos, Peter Kearney, Michal Tendera, John Lekakis, Jan Kjekshus, Jose Lopez-Sendon, Philippe Lechat, Markku S. Nieminen, Desmond G. Julian, Gianni Tognoni, Maria Angeles Alonso Garcia, Kristian Thygesen, Christian Torp-Pedersen, Jean-Jacques Blanc, Isabella Tritto, João Morais, Witold Ruzillo, Andrzej Budaj, Karl Swedberg, Juan Tamargo, Aldo P. Maggioni, Diego Ardissino, Werner Klein, Veronica Dean, Cristina Avendano, Finn Waagstein, Henry J. Dargie, Lars Wallentin, Maarten L. Simoons, Silvia G. Priori, Denis Clement, Helmut Drexler, and John J.V. McMurray

Subjects
biology, business.industry, MEDLINE, Expert consensus, Angiotensin-converting enzyme, Disease, Guideline, Bioinformatics, medicine.disease, Heart failure, biology.protein, Medicine, Cardiology and Cardiovascular Medicine, business
Abstract

[Expert Consensus document on angiotensin converting enzyme inhibitors in cardiovascular disease]

Published
2004
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10. Guidelines on Prevention, Diagnosis and Treatment of Infective Endocarditis Executive Summary The Task Force on Infective Endocarditis of the European Society of Cardiology

Author

Dieter, Horstkotte, Ferenc, Follath, Erno, Gutschik, Maria, Lengyel, Ali, Oto, Alain, Pavie, Jordi, Soler-Soler, Gaetano, Thiene, Alexander, von Graevenitz, Silvia G, Priori, Maria Angeles Alonso, Garcia, Jean-Jacques, Blanc, Andrzej, Budaj, Martin, Cowie, Veronica, Dean, Jaap, Deckers, Enrique, Fernández Burgos, John, Lekakis, Bertil, Lindahl, Gianfranco, Mazzotta, João, Morais, Otto A, Smiseth, Alec, Vahanian, François, Delahaye, Alexander, Parkhomenko, Gerasimos, Filipatos, Jan, Aldershvile, and Panos, Vardas

Subjects
Microbiological Techniques, medicine.medical_specialty, Executive summary, Task force, Process (engineering), business.industry, media_common.quotation_subject, Expert consensus, Endocarditis, Bacterial, medicine.disease, Anti-Bacterial Agents, Clinical Practice, Echocardiography, Infective endocarditis, Internal medicine, medicine, Cardiology, Humans, Quality (business), Cardiac Surgical Procedures, Cardiology and Cardiovascular Medicine, business, media_common
Abstract

Guidelines and Expert Consensus documents aim to present all the relevant evidence on a particular issue in order to help physicians to weigh the benefits and risks of a particular diagnostic or therapeutic procedure. They should be helpful in everyday clinical decision-making. A great number of Guidelines and Expert Consensus Documents have been issued in recent years by different organizations, the European Society of Cardiology (ESC) and by other related societies. By means of links to web sites of National Societies several hundred guidelines are available. This profusion can put at stake the authority and validity of guidelines, which can only be guaranteed if they have been developed by an unquestionable decision-making process. This is one of the reasons why the ESC and others have issued recommendations for formulating and issuing Guidelines and Expert Consensus Documents. In spite of the fact that standards for issuing good quality Guidelines and Expert Consensus Documents are well defined, recent surveys of Guidelines and Expert Consensus Documents published in peer-reviewed journals between 1985 and 1998 have shown that methodological standards were not complied within the vast majority of cases. It is therefore of great importance that guidelines and recommendations are presented in formats that are easily interpreted. Subsequently, their implementation programmes must also be well conducted. Attempts have been made to determine whether guidelines improve the quality of clinical practice and the utilisation of health resources. The ESC …

Published
2004
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11. ACC/AHA/ESC Guidelines for the Management of Patients With Supraventricular Arrhythmias—Executive Summary

Author

Carina, Blomström-Lundqvist, Melvin M, Scheinman, Etienne M, Aliot, Joseph S, Alpert, Hugh, Calkins, A John, Camm, W Barton, Campbell, David E, Haines, Karl H, Kuck, Bruce B, Lerman, D Douglas, Miller, Charlie Willard, Shaeffer, William G, Stevenson, Gordon F, Tomaselli, Elliott M, Antman, Sidney C, Smith, David P, Faxon, Valentin, Fuster, Raymond J, Gibbons, Gabriel, Gregoratos, Loren F, Hiratzka, Sharon Ann, Hunt, Alice K, Jacobs, Richard O, Russell, Silvia G, Priori, Jean Jacques, Blanc, Andzrej, Budaj, Enrique Fernandez, Burgos, Martin, Cowie, Jaap Willem, Deckers, Maria Angeles Alonso, Garcia, Werner W, Klein, John, Lekakis, Bertil, Lindahl, Gianfranco, Mazzotta, João Carlos Araujo, Morais, Ali, Oto, Otto, Smiseth, and Hans Joachim, Trappe

Subjects
Male, medicine.medical_treatment, Electrocardiography, CARDIAC THERAPY, Pregnancy, Tachycardia, Ectopic Junctional, Tachycardia, Supraventricular, Medicine, Age of Onset, Child, Aged, 80 and over, Executive summary, Cardiac Pacing, Artificial, Middle Aged, Atrial Flutter, Child, Preschool, Catheter Ablation, Costs and Cost Analysis, cardiovascular system, Cardiology, Female, Electrophysiologic Techniques, Cardiac, Cardiology and Cardiovascular Medicine, Anti-Arrhythmia Agents, Adult, Heart Defects, Congenital, Tachycardia, Ectopic Atrial, medicine.medical_specialty, Adolescent, Pregnancy Complications, Cardiovascular, Electric Countershock, Catheter ablation, Electric countershock, Cardiovascular therapy, Diagnosis, Differential, Heart Conduction System, Physiology (medical), Cardiovascular epidemiology, Internal medicine, Humans, Tachycardia, Atrioventricular Nodal Reentry, cardiovascular diseases, Tachycardia, Paroxysmal, Aged, Supraventricular arrhythmia, Task force, business.industry, Infant, Arrhythmias, Cardiac, Tachycardia, Sinus, Quality of Life, business, Case Management
Abstract

ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias--executive summary : a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Supraventricular Arrhythmias).

Published
2003
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12. ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias—executive summary A Report of the American College of Cardiology/American HeartAssociation Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines(Writing Committee to Develop Guidelines for the Management of Patients With Supraventricular Arrhythmias)Developed in collaboration with NASPE–Heart Rhythm Society

Author

Martin R. Cowie, Hugh Calkins, Elliott M. Antman, Gianfranco Mazzotta, Loren F. Hiratzka, Enrique Fernandez Burgos, Charlie Willard Shaeffer, Otto A. Smiseth, John Lekakis, Joseph S. Alpert, Ali Oto, Jaap W. Deckers, Maria Angeles Alonso Garcia, William G. Stevenson, Bruce B. Lerman, Werner Klein, Valentin Fuster, D. Douglas Miller, Sidney C. Smith, W. Barton Campbell, Carina Blomström-Lundqvist, Karl H. Kuck, Gabriel Gregoratosa, Hans Joachim Trappe, Silvia G. Priori, David P. Faxon, Melvin M. Scheinman, Sharon A. Hunt, A Budaj, Bertil Lindahl, Richard O. Russell, Jean Jacques Blanc, João Morais, A. John Camm, Etienne Aliot, Gordon F. Tomaselli, David E. Haines, Raymond J. Gibbons, and Alice K. Jacobs

Subjects
Pediatrics, medicine.medical_specialty, Supraventricular arrhythmia, Executive summary, Task force, business.industry, medicine.disease, Clinical decision making, cardiovascular system, Medicine, cardiovascular diseases, Medical emergency, Cardiology and Cardiovascular Medicine, business
Abstract

These practice guidelines are intended to assist physicians in clinical decision making by describing a range of generally acceptable approaches for the diagnosis and management of supraventricular arrhythmias. These guidelines attempt to define practices that meet the needs of most patients in most

Published
2003
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13. European guidelines on cardiovascular disease prevention in clinical practice Third Joint Task Force of European and other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of eight societies and by invited experts)

Author

Renata Cifkova, Mike Rayner, Troels Thomsen, David R. Wood, Keith McGregor, Kalevi Pyörälä, Steven Humphries, Redford Williams, James Shepherd, Volkert Manger Cats, Annika Rosengren, Brian Oldenburg, Ali Oto, Ole Faergeman, Silvia G. Priori, Maciek Godycki-Cwirko, Jaap W. Deckers, Ian D. Graham, Carl-David Agardh, Neil Schneiderman, Jean Dallongeville, Maarten L. Simoons, Enrique Fernandez Burgos, Hans Christian Deter, Mario Sammut, Gianfranco Mazzotta, Guy De Backer, Giuseppe Mancia, Anthony Fitzgerald, Jean-Pierre Bassand, João Morais, John Lekakis, Otto A. Smiseth, Martin R. Cowie, Vedat Sansoy, Knut Borch-Johnsen, Pekka Puska, Carlos Brotons, Bertil Lindahl, Sigmund Silber, Robert J. Heine, Andrzej Budaj, Christian Albus, Susana Sans, Ettore Ambrosioni, Jean-Jacques Blanc, Alberto Zanchetti, Nuri Bages, Anthony M. Heagerty, Maria Angeles Alonso Garcia, Michal Tendera, Jose L. Rodicio, Joep Perk, Gunilla Burell, Ronan M. Conroy, Johannes Siegrist, Hans-Joachim Trappe, Philip Home, Silvia Priori, Udo Sechtem, Antti Uutela, Kristina Orth-Gomér, Shah Ebrahim, Christoph Hermann-Lingen, John Yarnell, and Veronica Dean

Subjects
medicine.medical_specialty, Medical education, business.industry, Process (engineering), media_common.quotation_subject, Alternative medicine, MEDLINE, Guideline, Task (project management), Clinical Practice, medicine, Quality (business), Cardiology and Cardiovascular Medicine, Risk assessment, business, media_common
Abstract

Guidelines aim to present all the relevant evidence on a particular issue in order to help physicians to weigh the benefits and risks of a particular diagnostic or therapeutic procedure. They should be helpful in everyday clinical decision-making. A great number of guidelines have been issued in recent years by different organizations-European Society of Cardiology (ESC), American Heart Association (AHA), American College of Cardiology (ACC), and other related societies. By means of links to web sites of National Societies several hundred guidelines are available. This profusion can put at stake the authority and validity of guidelines, which can only be guaranteed if they have been developed by an unquestionable decision-making process. This is one of the reasons why the ESC and others have issued recommendations for formulating and issuing guidelines. In spite of the fact that standards for issuing good quality guidelines are well defined, recent surveys of guidelines published in peer-reviewed journals between 1985 and 1998 have shown that methodological standards were not complied with in the vast majority of cases. It is therefore of great importance that guidelines and recommendations are presented in formats that are easily interpreted. Subsequently, their implementation programmes must also be well conducted. Attempts have been made to determine whether guidelines improve the quality of clinical practice and the utilization of health resources. In addition, the legal implications of medical guidelines have been discussed and examined, resulting in position documents, which have been published by a specific Task Force. The ESC Committee for Practice Guidelines (CPG) supervises and coordinates the preparation of new Guidelines and Expert Consensus Documents produced by Task Forces, expert groups or consensus panels. The Committee is also responsible for the endorsement of these guidelines or statements. The rationale for an active approach to the prevention of cardiovascular diseases (CVD) is …

Published
2003
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14. Expert consensus document on management of cardiovascular diseases during pregnancy The Task Force on the Management of Cardiovascular Diseases During Pregnancy of the European Society of Cardiology

Author

Carina Blomström-Lundqvist, Pilar Tornos, Werner Klein, Bernard Jung, Maria Angeles Alonso Garcia, Sigmund Silber, Adam Torbicki, Ali Oto, Jaap W. Deckers, Anne H. Child, Patricia Presbitero, Henry J. Dargie, Jaromír Hradec, Gianfranco Mazzotta, Hans-Joachim Trappe, Dominique Poumeyrol-Jumeau, Celia M. Oakley, Veronica Dean, Marcus Flather, and Alexander Parkhomenko

Subjects
Pregnancy, medicine.medical_specialty, biology, business.industry, Task force, Garcia, Expert consensus, medicine.disease, biology.organism_classification, Internal medicine, medicine, Cardiology, Cardiology and Cardiovascular Medicine, business
Abstract

The Task Force on the Management of Cardiovascular Diseases During Pregnancy of the European Society of Cardiology Task Force Members, Celia Oakley, Chairperson, Anne Child, Bernard Iung, Patricia Presbitero, Pilar Tornos, CPGPC Members, Werner Klein, Chairperson, Maria Angeles Alonso Garcia, Carina Blomstrom-Lundqvist, Guy de Backer, Henry Dargie, Jaap Deckers, Marcus Flather, Jaromir Hradec, Gianfranco Mazzotta, Ali Oto, Alexander Parkhomenko, Sigmund Silber, Adam Torbicki, Hans-Joachim Trappe, ESC Staff, Veronica Dean, Dominique Poumeyrol-Jumeau

Published
2003
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16. Intracellular retention and degradation of human mutant variant of a alpha1-antitrypsin in stably transfected Chinese hamster ovary cell lines

Author

Maria Angeles Alonso, Ernesto Ciccarelli, Alex Bollen, Paul Jacobs, Fernando Alvarez, and D Cresteil

Subjects
Glycosylation, Molecular Sequence Data, Golgi Apparatus, Alpha (ethology), CHO Cells, Cyclopentanes, Biology, Endoplasmic Reticulum, Transfection, Biochemistry, Cell Line, chemistry.chemical_compound, symbols.namesake, Cricetinae, Animals, Humans, Secretion, Monensin, Brefeldin A, Base Sequence, Tunicamycin, Chinese hamster ovary cell, Endoplasmic reticulum, Biological Transport, Golgi apparatus, Molecular biology, Oligodeoxyribonucleotides, chemistry, alpha 1-Antitrypsin, symbols, Plasmids
Abstract

Normal (PiM) and mutant (PiZ) variants of human alpha 1-antitrypsin (alpha 1-AT) cDNA, cloned into the pTnd eucaryotic expression vector, were used to derive recombinant Chinese hamster ovary cell lines permanently expressing the corresponding proteins. Secretion, accumulation and glycosylation of PiM and PiZ alpha 1-AT proteins were studied in the presence of various transport-impairing drugs. Pulse-chase, followed by immunoprecipitation as well as immunofluorescence experiments showed that the PiZ alpha 1-AT undergoes continuous degradation that was prevented by Brefeldin A but not by incubation of cells at 16 degrees C. Moreover, monensin partially impaired the glycosylation of both PiM and PiZ alpha 1-AT but not their secretion nor the degradation of PiZ alpha 1-AT. Those results suggest that PiZ alpha 1-AT degradation occurs in the cis-Golgi network, a compartment located between the endoplasmic reticulum and the Golgi stack. The process did not apparently involve lysosomes since it was insensitive to chloroquine. In addition, inhibition of PiM and PiZ alpha 1-AT glycosylation and secretion by tunicamycin did not result in the accumulation of the protein, but instead in its rapid lag-free degradation. Treatment of cells with the A23187 ionophore, for a short (60 min) but not a long (24 h) period, improved the secretion of PiZ alpha 1-AT in a similar way as it affects retention of naturally endoplasmic-reticulum-resident proteins, suggesting that the small proportion of PiZ alpha 1-AT which is not degraded or secreted, but accumulates in the endoplasmic reticulum, is back transported as a partially glycosylated species from the post endoplasmic reticulum compartment in which degradation takes place.

Published
1993
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17. BiP expression is not increased by the accumulation of PiZ α1-antitrypsin in the endoplasmic reticulum

Author

Alex Bollen, Théophile Soni, Paul Jacobs, Danièle Cresteil, Maria Angeles Alonso, Ernesto Ciccarelli, and Fernando Alvarez

Subjects
Lung Diseases, BiP, Protein Conformation, Biophysics, Protein aggregation, Biology, Endoplasmic Reticulum, Biochemistry, PiM, Cell Line, Structural Biology, Gene expression, Genetics, Animals, Humans, Secretion, RNA, Messenger, Northern blot, PiZ, Endoplasmic Reticulum Chaperone BiP, Molecular Biology, Heat-Shock Proteins, Messenger RNA, Liver Diseases, Binding protein, Endoplasmic reticulum, Cell Biology, Blotting, Northern, Molecular biology, Blot, α1-Antitrypsin, Liver, alpha 1-Antitrypsin, Mutation, Carrier Proteins, Molecular Chaperones
Abstract

PiZ, a mutant human alpha 1-antitrypsin, is associated with liver and pulmonary disease and is characterized by defective secretion and accumulation of the protein in the endoplasmic reticulum. We tested the hypothesis that BiP (a protein that binds newly synthesized protein in the endoplasmic reticulum, prevents secretion of incorrectly folded protein, and solubilizes protein aggregates), could play a part in the retention of PiZ alpha 1-antitrypsin in the endoplasmic reticulum. Subcellular fractions from PiM (normal) and PiZ livers were prepared and analyzed by immunoblotting. No increase of BiP was detected in the PiZ liver. In addition, when total RNA from the same livers were analyzed by slot and Northern blot hybridization, no difference was found in the level of BiP mRNA between PiM and PiZ livers. Similar results were found in clones of CHO and MDCK cells transfected with PiM of PiZ alpha 1-antitrypsin cDNAs. These results indicate that BiP does not play a part in the retention of PiZ alpha 1-antitrypsin and suggest that PiZ protein is not misfolded.

Published
1990
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18. [Guidelines on the management of stable angina pectoris: executive summary]

Author

Kim, Fox, Maria Angeles, Alonso Garcia, Diego, Ardissino, Pawel, Buszman, Paolo G, Camici, Filippo, Crea, Caroline, Daly, Guy, De Backer, Paul, Hjemdahl, José, Lopez-Sendon, Jean, Marco, João, Morais, John, Pepper, Udo, Sechtem, Maarten, Simoons, Kristian, Thygesen, Silvia G, Priori, Jean-Jacques, Blanc, Andrzej, Budaj, John, Camm, Veronica, Dean, Jaap, Deckers, Kenneth, Dickstein, John, Lekakis, Keith, McGregor, Marco, Metra, Ady, Osterspey, Juan, Tamargo, José L, Zamorano, Felicita, Andreotti, Harald, Becher, Rainer, Dietz, Alan, Fraser, Huon, Gray, Rosa Ana, Hernandez Antolin, Kurt, Huber, Dimitris T, Kremastinos, Attilio, Maseri, Hans-Jaochim, Nesser, Tomasz, Pasierski, Ulrich, Sigwart, Marco, Tubaro, and Michael, Weis

Subjects
Exercise Test, Myocardial Revascularization, Humans, Risk Assessment, Algorithms, Angina Pectoris
Published
2006

19. [Guidelines on the management of stable angina pectoris; the experts of the European Society of Cardiology on the management of stable angina pectoris]

Author

Kim, Fox, Maria Angeles Alonso, Garcia, Diego, Ardissino, Paweł, Buszman, Paolo G, Camici, Filippo, Crea, Caroline, Daly, Guy de, Backer, Paul, Hjemdahl, Jose, Lopez-Sendon, Jean, Marco, Joao, Morais, John, Pepper, Udo, Sechtem, Maarten, Simoons, and Kristian, Thygsen

Subjects
Male, Clinical Trials as Topic, Vasodilator Agents, Age Factors, Coronary Disease, Comorbidity, Coronary Angiography, Angina Pectoris, Electrocardiography, Sex Factors, Heart Function Tests, Exercise Test, Myocardial Revascularization, Humans, Female, Angioplasty, Balloon, Coronary, Randomized Controlled Trials as Topic
Published
2006

21. Executive summary of the guidelines on the diagnosis and treatment of acute heart failure:The Task Force on Acute Heart Failure of the European Society of Cardiology

Author

Nieminen, Markku S., Böhm, Michael, Cowie, Martin R., Drexler, Helmut, Filippatos, Gerasimos S., Jondeau, Guillaume, Hasin, Yonathan, Lopez-Sendon, Jose, Mebazaa, Alexandre, Metra, Marco, Rhodes, Andrew, Swedberg, Karl, Priori, Silvia G., Garcia, Maria Angeles Alonso, Blanc, Jean-Jacques, Budaj, Andrzej, Dean, Veronica, Deckers, Jaap, Burgos, Enrique Fernandez, Lekakis, John, Lindahl, Bertil, Mazzotta, Gianfranco, Morais, Joao, Oto, Ali, Smiseth, Otto A., Dickstein, Kenneth, Albuquerque, Anibal, Conthe, Pedro, Crespo-Leiro, Maria, Ferrari, Roberto, Follath, Ferenc, Gavazzi, Antonello, Janssens, Uwe, Komajda, Michel, Moreno, Rui, Singer, Mervyn, Singh, Satish, Tendera, Michal, and Thygesen, Kristian Anton

Published
2005

22. Guidelines on management (diagnosis and treatment) of syncope-update 2004. Executive Summary

Author

Michele, Brignole, Paolo, Alboni, David G, Benditt, Lennart, Bergfeldt, Jean-Jacques, Blanc, Poul Erik Bloch, Thomsen, J, Gert van Dijk, Adam, Fitzpatrick, Stefan, Hohnloser, Jan, Janousek, Wishwa, Kapoor, Rose Anne, Kenny, Piotr, Kulakowski, Giulio, Masotti, Angel, Moya, Antonio, Raviele, Richard, Sutton, George, Theodorakis, Andrea, Ungar, Wouter, Wieling, Silvia G, Priori, Maria Angeles Alonso, Garcia, Andrzej, Budaj, Martin, Cowie, Jaap, Deckers, Enrique Fernandez, Burgos, John, Lekakis, Bertil, Lindhal, Gianfranco, Mazzotta, João, Morais, Ali, Oto, Otto, Smiseth, Carlo, Menozzi, Hugo, Ector, Panos, Vardas, ACS - Amsterdam Cardiovascular Sciences, and General Internal Medicine

Subjects
Automobile Driving, Electrocardiography, Tachycardia, Ventricular, Humans, Physical Examination, Syncope
Published
2004

23. Management of grown up congenital heart disease

Author

John, Deanfield, Erik, Thaulow, Carol, Warnes, Gary, Webb, Frantizek, Kolbel, Andreas, Hoffman, Keld, Sorenson, Harald, Kaemmer, Ulf, Thilen, Margaret, Bink-Boelkens, Laurence, Iserin, Luciano, Daliento, Eric, Silove, Andrew, Redington, Pascal, Vouhe, Silvia, Priori, Maria Angeles, Alonso, Jean-Jacques, Blanc, Andrzej, Budaj, Martin, Cowie, Jaap, Deckers, Enrique, Fernandez Burgos, John, Lekakis, Bertil, Lindahl, Gianfranco, Mazzotta, Joao, Morais, Ali, Oto, Otto, Smiseth, Hans Joachim, Trappe, Werner, Klein, Carina, Blömstrom-Lundqvist, Guy, de Backer, Jaromir, Hradec, Alexander, Parkhomenko, Patrizia, Presbitero, and Adam, Torbicki

Subjects
Male, Pacemaker, Artificial, Heart disease, Cardiac Care Facilities, CARDIAC THERAPY, Self help groups, QUALITY-OF-LIFE, Pregnancy, YOUNG-ADULTS, Anesthesia, Referral and Consultation, MUSTARD OPERATION, GREAT-ARTERIES, organization of care, congenital heart disease, Self-Help Groups, Contraception, grown-up congenital heart disease, Great arteries, Cardiology, Workforce, Female, Cardiology and Cardiovascular Medicine, management, PREGNANT-WOMEN, Adult, Diagnostic Imaging, Employment, Heart Defects, Congenital, medicine.medical_specialty, Adolescent, LONG-TERM, Pregnancy Complications, Cardiovascular, SIMPLE TRANSPOSITION, Genetic Counseling, Education, Internal medicine, medicine, Endocarditis, Humans, RADIOFREQUENCY ABLATION, Cardiac Surgical Procedures, Exercise, Cyanosis, Insurance, Health, business.industry, ORTHOTOPIC CARDIAC TRANSPLANTATION, Mustard operation, Arrhythmias, Cardiac, Endocarditis, Bacterial, medicine.disease, CEREBROVASCULAR EVENTS, Bacterial etiology, specialist centres, Quality of Life, business, Delivery of Health Care
Published
2003

24. Executive summary of the guidelines on the diagnosis and treatment of acute heart failure : the Task Force on Acute Heart Failure of the European Society of Cardiology.

Author

Nieminen, Markku S, Böhm, Michael, Cowie, Martin R, Drexler, Helmut, Filippatos, Gerasimos S, Jondeau, Guillaume, Hasin, Yonathan, Lopez-Sendon, José, Mebazaa, Alexandre, Metra, Marco, Rhodes, Andrew, Swedberg, Karl, Priori, Silvia G, Garcia, Maria Angeles Alonso, Blanc, Jean-Jacques, Budaj, Andrzej, Dean, Veronica, Deckers, Jaap, Burgos, Enrique Fernandez, Lekakis, John, Lindahl, Bertil, Mazzotta, Gianfranco, Morais, João, Oto, Ali, Smiseth, Otto A, Dickstein, Kenneth, Albuquerque, Anibal, Conthe, Pedro, Crespo-Leiro, Maria, Ferrari, Roberto, Follath, Ferenc, Gavazzi, Antonello, Janssens, Uwe, Komajda, Michel, Morais, Joaõ, Moreno, Rui, Singer, Mervyn, Singh, Satish, Tendera, Michal, Thygesen, Kristian, Nieminen, Markku S, Böhm, Michael, Cowie, Martin R, Drexler, Helmut, Filippatos, Gerasimos S, Jondeau, Guillaume, Hasin, Yonathan, Lopez-Sendon, José, Mebazaa, Alexandre, Metra, Marco, Rhodes, Andrew, Swedberg, Karl, Priori, Silvia G, Garcia, Maria Angeles Alonso, Blanc, Jean-Jacques, Budaj, Andrzej, Dean, Veronica, Deckers, Jaap, Burgos, Enrique Fernandez, Lekakis, John, Lindahl, Bertil, Mazzotta, Gianfranco, Morais, João, Oto, Ali, Smiseth, Otto A, Dickstein, Kenneth, Albuquerque, Anibal, Conthe, Pedro, Crespo-Leiro, Maria, Ferrari, Roberto, Follath, Ferenc, Gavazzi, Antonello, Janssens, Uwe, Komajda, Michel, Morais, Joaõ, Moreno, Rui, Singer, Mervyn, Singh, Satish, Tendera, Michal, and Thygesen, Kristian

Published
2005

25. Guidelines on diagnosis and treatment of pulmonary arterial hypertension. The Task Force on Diagnosis and Treatment of Pulmonary Arterial Hypertension of the European Society of Cardiology.

Author

Galiè, Nazzareno, Torbicki, Adam, Barst, Robyn, Dartevelle, Philippe, Haworth, Sheila, Higenbottam, Tim, Olschewski, Horst, Peacock, Andrew, Pietra, Giuseppe, Rubin, Lewis J, Simonneau, Gerald, Priori, Silvia G, Garcia, Maria Angeles Alonso, Blanc, Jean-Jacques, Budaj, Andrzej, Cowie, Martin, Dean, Verconcia, Deckers, Jaap, Burgos, Enrique Fernandez, Lekakis, John, Lindahl, Bertil, Mazzotta, Gianfranco, McGregor, Keith, Morais, João, Oto, Ali, Smiseth, Otto A, Barbera, Joan Albert, Gibbs, Simon, Hoeper, Marius, Humbert, Marc, Naeije, Robert, Pepke-Zaba, Joanna, Galiè, Nazzareno, Torbicki, Adam, Barst, Robyn, Dartevelle, Philippe, Haworth, Sheila, Higenbottam, Tim, Olschewski, Horst, Peacock, Andrew, Pietra, Giuseppe, Rubin, Lewis J, Simonneau, Gerald, Priori, Silvia G, Garcia, Maria Angeles Alonso, Blanc, Jean-Jacques, Budaj, Andrzej, Cowie, Martin, Dean, Verconcia, Deckers, Jaap, Burgos, Enrique Fernandez, Lekakis, John, Lindahl, Bertil, Mazzotta, Gianfranco, McGregor, Keith, Morais, João, Oto, Ali, Smiseth, Otto A, Barbera, Joan Albert, Gibbs, Simon, Hoeper, Marius, Humbert, Marc, Naeije, Robert, and Pepke-Zaba, Joanna

Published
2004

26. Guidelines on prevention, diagnosis and treatment of infective endocarditis executive summary; the task force on infective endocarditis of the European society of cardiology

Author

Horstkotte, Dieter, Follath, Ferenc, Gutschik, Erno, Lengyel, Maria, Oto, Ali, Pavie, Alain, Soler-Soler, Jordi, Thiene, Gaetano, von Graevenitz, Alexander, Priori, Silvia G, Garcia, Maria Angeles Alonso, Blanc, Jean-Jacques, Budaj, Andrzej, Cowie, Martin, Dean, Veronica, Deckers, Jaap, Fernández Burgos, Enrique, Lekakis, John, Lindahl, Bertil, Mazzotta, Gianfranco, Morais, Joao, Smiseth, Otto A., Vahanian, Alec, Delahaye, Franqois, Parkhomenko, Alexander, Filipatos, Gerasimos, Aldershvile, Jan, Vardas, Panos, Horstkotte, Dieter, Follath, Ferenc, Gutschik, Erno, Lengyel, Maria, Oto, Ali, Pavie, Alain, Soler-Soler, Jordi, Thiene, Gaetano, von Graevenitz, Alexander, Priori, Silvia G, Garcia, Maria Angeles Alonso, Blanc, Jean-Jacques, Budaj, Andrzej, Cowie, Martin, Dean, Veronica, Deckers, Jaap, Fernández Burgos, Enrique, Lekakis, John, Lindahl, Bertil, Mazzotta, Gianfranco, Morais, Joao, Smiseth, Otto A., Vahanian, Alec, Delahaye, Franqois, Parkhomenko, Alexander, Filipatos, Gerasimos, Aldershvile, Jan, and Vardas, Panos

Published
2004
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27. ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias--executive summary : a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Supraventricular Arrhythmias).

Author

Blomström-Lundqvist, Carina, Scheinman, Melvin M, Aliot, Etienne M, Alpert, Joseph S, Calkins, Hugh, Camm, A John, Campbell, W Barton, Haines, David E, Kuck, Karl H, Lerman, Bruce B, Miller, D Douglas, Shaeffer, Charlie Willard, Stevenson, William G, Tomaselli, Gordon F, Antman, Elliott M, Smith, Sidney C, Faxon, David P, Fuster, Valentin, Gibbons, Raymond J, Gregoratos, Gabriel, Hiratzka, Loren F, Hunt, Sharon Ann, Jacobs, Alice K, Russell, Richard O, Priori, Silvia G, Blanc, Jean-Jacques, Budaj, Andzrej, Burgos, Enrique Fernandez, Cowie, Martin, Deckers, Jaap Willem, Garcia, Maria Angeles Alonso, Klein, Werner W, Lekakis, John, Lindahl, Bertil, Mazzotta, Gianfranco, Morais, João Carlos Araujo, Oto, Ali, Smiseth, Otto, Trappe, Hans-Joachim, Blomström-Lundqvist, Carina, Scheinman, Melvin M, Aliot, Etienne M, Alpert, Joseph S, Calkins, Hugh, Camm, A John, Campbell, W Barton, Haines, David E, Kuck, Karl H, Lerman, Bruce B, Miller, D Douglas, Shaeffer, Charlie Willard, Stevenson, William G, Tomaselli, Gordon F, Antman, Elliott M, Smith, Sidney C, Faxon, David P, Fuster, Valentin, Gibbons, Raymond J, Gregoratos, Gabriel, Hiratzka, Loren F, Hunt, Sharon Ann, Jacobs, Alice K, Russell, Richard O, Priori, Silvia G, Blanc, Jean-Jacques, Budaj, Andzrej, Burgos, Enrique Fernandez, Cowie, Martin, Deckers, Jaap Willem, Garcia, Maria Angeles Alonso, Klein, Werner W, Lekakis, John, Lindahl, Bertil, Mazzotta, Gianfranco, Morais, João Carlos Araujo, Oto, Ali, Smiseth, Otto, and Trappe, Hans-Joachim

Published
2003

28. ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias--executive summary. a report of the American college of cardiology/American heart association task force on practice guidelines and the European society of cardiology committee for practice guidelines (writing committee to develop guidelines for the management of patients with supraventricular arrhythmias) developed in collaboration with NASPE-Heart Rhythm Society.

Author

Blomström-Lundqvist, Carina, Scheinman, Melvin M, Aliot, Etienne M, Alpert, Joseph S, Calkins, Hugh, Camm, A John, Campbell, W Barton, Haines, David E, Kuck, Karl H, Lerman, Bruce B, Miller, D Douglas, Shaeffer, Charlie Willard, Stevenson, William G, Tomaselli, Gordon F, Antman, Elliott M, Smith, Sidney C, Faxon, David P, Fuster, Valentin, Gibbons, Raymond J, Gregoratos, Gabriel, Hiratzka, Loren F, Hunt, Sharon Ann, Jacobs, Alice K, Russell, Richard O, Priori, Silvia G, Blanc, Jean Jacques, Budaj, Andzrej, Burgos, Enrique Fernandez, Cowie, Martin, Deckers, Jaap Willem, Garcia, Maria Angeles Alonso, Klein, Werner W, Lekakis, John, Lindahl, Bertil, Mazzotta, Gianfranco, Morais, Joáo Carlos Araujo, Oto, Ali, Smiseth, Otto, Trappe, Hans Joachim, Blomström-Lundqvist, Carina, Scheinman, Melvin M, Aliot, Etienne M, Alpert, Joseph S, Calkins, Hugh, Camm, A John, Campbell, W Barton, Haines, David E, Kuck, Karl H, Lerman, Bruce B, Miller, D Douglas, Shaeffer, Charlie Willard, Stevenson, William G, Tomaselli, Gordon F, Antman, Elliott M, Smith, Sidney C, Faxon, David P, Fuster, Valentin, Gibbons, Raymond J, Gregoratos, Gabriel, Hiratzka, Loren F, Hunt, Sharon Ann, Jacobs, Alice K, Russell, Richard O, Priori, Silvia G, Blanc, Jean Jacques, Budaj, Andzrej, Burgos, Enrique Fernandez, Cowie, Martin, Deckers, Jaap Willem, Garcia, Maria Angeles Alonso, Klein, Werner W, Lekakis, John, Lindahl, Bertil, Mazzotta, Gianfranco, Morais, Joáo Carlos Araujo, Oto, Ali, Smiseth, Otto, and Trappe, Hans Joachim

Published
2003

29. ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias∗∗This document does not cover atrial fibrillation; atrial fibrillation is covered in the ACC/AHA/ESC guidelines on the management of patients with atrial fibrillation found on the ACC, AHA, and ESC Web sites.—executive summary

Author

Blomström-Lundqvist, Carina, primary, Scheinman, Melvin M, additional, Aliot, Etienne M, additional, Alpert, Joseph S, additional, Calkins, Hugh, additional, Camm, A.John, additional, Campbell, W.Barton, additional, Haines, David E, additional, Kuck, Karl H, additional, Lerman, Bruce B, additional, Miller, D.Douglas, additional, Shaeffer, Charlie Willard, additional, Stevenson, William G, additional, Tomaselli, Gordon F, additional, Antman, Elliott M, additional, Smith, Sidney C, additional, Faxon, David P, additional, Fuster, Valentin, additional, Gibbons, Raymond J, additional, Gregoratos, Gabriel, additional, Hiratzka, Loren F, additional, Hunt, Sharon Ann, additional, Jacobs, Alice K, additional, Russell, Richard O, additional, Priori, Silvia G, additional, Blanc, Jean-Jacques, additional, Budaj, Andzrej, additional, Burgos, Enrique Fernandez, additional, Cowie, Martin, additional, Deckers, Jaap Willem, additional, Garcia, Maria Angeles Alonso, additional, Klein, Werner W, additional, Lekakis, John, additional, Lindahl, Bertil, additional, Mazzotta, Gianfranco, additional, Morais, João Carlos Araujo, additional, Oto, Ali, additional, Smiseth, Otto, additional, and Trappe, Hans-Joachim, additional

Published
2003
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30. ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias∗∗This document does not cover atrial fibrillation; atrial fibrillation is covered in the ACC/AHA/ESC guidelines on the management of patients with atrial fibrillation found on the ACC, AHA, and ESC Web sites.—executive summary a report of the American college of cardiology/American heart association task force on practice guidelines and the European society of cardiology committee for practice guidelines (writing committee to develop guidelines for the management of patients with supraventricular arrhythmias) Developed in Collaboration with NASPE-Heart Rhythm Society

Author

Carina Blomström-Lundqvist, Melvin M Scheinman, Etienne M Aliot, Joseph S Alpert, Hugh Calkins, A.John Camm, W.Barton Campbell, David E Haines, Karl H Kuck, Bruce B Lerman, D.Douglas Miller, Charlie Willard Shaeffer, William G Stevenson, Gordon F Tomaselli, Elliott M Antman, Sidney C Smith, David P Faxon, Valentin Fuster, Raymond J Gibbons, Gabriel Gregoratos, Loren F Hiratzka, Sharon Ann Hunt, Alice K Jacobs, Richard O Russell, Silvia G Priori, Jean-Jacques Blanc, Andzrej Budaj, Enrique Fernandez Burgos, Martin Cowie, Jaap Willem Deckers, Maria Angeles Alonso Garcia, Werner W Klein, John Lekakis, Bertil Lindahl, Gianfranco Mazzotta, João Carlos Araujo Morais, Ali Oto, Otto Smiseth, and Hans-Joachim Trappe

Subjects
medicine.medical_specialty, Supraventricular arrhythmia, Executive summary, Task force, business.industry, medicine.medical_treatment, MEDLINE, Catheter ablation, Guideline, medicine.disease, arrhythmia, tachycardia, ablation, drugs, Heart Rhythm, Quality of life (healthcare), Internal medicine, cardiovascular system, medicine, Cardiology, ACC/AHA/ESC Practice Guidelines, cardiovascular diseases, Medical emergency, Cardiology and Cardiovascular Medicine, business
Abstract

These practice guidelines are intended to assist physicians in clinical decision making by describing a range of generally acceptable approaches for the diagnosis and management of supraventricular arrhythmias. These guidelines attempt to define practices that meet the needs of most patients in most

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32. [Guidelines on the management of stable angina pectoris; the experts of the European Society of Cardiology on the management of stable angina pectoris].

Author

Fox K, Garcia MA, Ardissino D, Buszman P, Camici PG, Crea F, Daly C, Backer Gd, Hjemdahl P, Lopez-Sendon J, Marco J, Morais J, Pepper J, Sechtem U, Simoons M, and Thygsen K

Subjects
Age Factors, Angina Pectoris epidemiology, Angioplasty, Balloon, Coronary, Clinical Trials as Topic standards, Comorbidity, Coronary Angiography, Coronary Disease diagnosis, Coronary Disease epidemiology, Coronary Disease therapy, Electrocardiography, Exercise Test, Female, Heart Function Tests, Humans, Male, Myocardial Revascularization, Randomized Controlled Trials as Topic standards, Sex Factors, Angina Pectoris diagnosis, Angina Pectoris therapy, Vasodilator Agents pharmacology, Vasodilator Agents therapeutic use
Published
2006

33. Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology.

Author

Fox K, Garcia MA, Ardissino D, Buszman P, Camici PG, Crea F, Daly C, De Backer G, Hjemdahl P, Lopez-Sendon J, Marco J, Morais J, Pepper J, Sechtem U, Simoons M, Thygesen K, Priori SG, Blanc JJ, Budaj A, Camm J, Dean V, Deckers J, Dickstein K, Lekakis J, McGregor K, Metra M, Morais J, Osterspey A, Tamargo J, and Zamorano JL

Subjects
Aged, Angina Pectoris diagnosis, Angioplasty, Balloon, Coronary methods, Cardiotonic Agents therapeutic use, Clinical Laboratory Techniques, Coronary Angiography methods, Coronary Artery Bypass methods, Electrocardiography methods, Exercise Test methods, Female, Humans, Male, Medical History Taking methods, Middle Aged, Myocardial Revascularization methods, Referral and Consultation, Risk Assessment, Stents, Angina Pectoris therapy
Published
2006
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34. Guidelines on diagnosis and treatment of pulmonary arterial hypertension. The Task Force on Diagnosis and Treatment of Pulmonary Arterial Hypertension of the European Society of Cardiology.

Author

Galiè N, Torbicki A, Barst R, Dartevelle P, Haworth S, Higenbottam T, Olschewski H, Peacock A, Pietra G, Rubin LJ, Simonneau G, Priori SG, Garcia MA, Blanc JJ, Budaj A, Cowie M, Dean V, Deckers J, Burgos EF, Lekakis J, Lindahl B, Mazzotta G, McGregor K, Morais J, Oto A, Smiseth OA, Barbera JA, Gibbs S, Hoeper M, Humbert M, Naeije R, and Pepke-Zaba J

Subjects
Arterial Occlusive Diseases complications, Connective Tissue Diseases complications, Dyspnea etiology, HIV Infections complications, Hemangioma complications, Humans, Hypertension, Pulmonary etiology, Risk Factors, Cardiovascular Agents therapeutic use, Hypertension, Pulmonary diagnosis, Hypertension, Pulmonary therapy
Published
2004
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35. Guidelines on management (diagnosis and treatment) of syncope-update 2004. Executive Summary.

Author

Brignole M, Alboni P, Benditt DG, Bergfeldt L, Blanc JJ, Thomsen PE, Gert van Dijk J, Fitzpatrick A, Hohnloser S, Janousek J, Kapoor W, Kenny RA, Kulakowski P, Masotti G, Moya A, Raviele A, Sutton R, Theodorakis G, Ungar A, Wieling W, Priori SG, Garcia MA, Budaj A, Cowie M, Deckers J, Burgos EF, Lekakis J, Lindhal B, Mazzotta G, Morais J, Oto A, Smiseth O, Menozzi C, Ector H, and Vardas P

Subjects
Automobile Driving, Electrocardiography methods, Humans, Physical Examination, Tachycardia, Ventricular complications, Tachycardia, Ventricular diagnosis, Syncope etiology, Syncope therapy
Published
2004
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