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Primary rhabdomyosarcoma (RMS) of the adult prostate is a very rare tumor with only 45 cases published to date. The clinical course of RMS of the prostate is very aggressive, and prognosis is very poor. Here we describe two cases of primary RMS of the prostate of adult patients and discuss the differential diagnosis of RMS with other mesenchymal tumors of prostate. The first patient was a 50-year-old man who clinically presented with urinary retention and hematuria, low serum prostate-specific antigen, moderate prostatomegaly, and multiple metastases as shown by computed tomography. Histological examination revealed a diffuse "small round blue cell" proliferation with an intermingled population of larger cells with rhabdomyoblastic differentiation that showed immunoreactivity for desmin and MYF4 (myogenin). Molecular and cytogenetic studies did not reveal recurrent chromosomal translocations associated with RMSs and other sarcomas. The patient underwent doxorubicin (adriamycin) treatment without disease progression during the whole follow-up period of 7 months. The second patient was a 39-year-old man who presented with urinary retention, an increased serum prostate-specific antigen level, extensive prostatomegaly, enlarged abdominal and inguinal lymph nodes, and skeletal metastases. Histological examination revealed a tumoral proliferation with a small round blue aspect and diffuse immunoreactivity for desmin and MYF4 (myogenin). Fluorescence in situ hybridization revealed a FOXO1 translocation, consistent with a diagnosis of alveolar-type RMS. The patient followed a multimodal treatment and died of the disease after its progression.

Six-membered cyclic sulfamidates are prepared in high yields by treatment of allenic sulfamates with readily available Ph3PAuNTf2. The reaction enables formation of N-substituted quaternary centres in high yields. The relative stereochemistry has been unambiguously determined. A π-rearrangement is faster than hydroamination in the case of an allyl-substituted sulfamate and a mechanism is proposed for this process.

The first gold-catalyzed preparation of cyclic sulfamidates, leading to a range of unusually substituted and sterically hindered products under mild conditions is reported.

Al2O3/8YSZ composites with a wide range of alumina compositions, from 0 to 50 wt.%, have been prepared and characterised. The electrical properties and the microstructure were studied by complex impedance spectroscopy and scanning electron microscopy techniques, respectively. Simple models derived from effective medium theories were used to predict the qualitative trend of electrical conductivity versus Al2O3 volume fraction and a comparison with the experimental data is reported.

Six-membered cyclic sulfamidates are prepared in high yields by treatment of allenic sulfamates with readily available gold(I) complexes. The reaction enables formation of N-substituted quaternary centres and complements existing processes for sulfamidate formation.

The recent interest in the (Sr, Mg) doped LaGaO3 family compounds as electrolyte for Intermediate Temperature Solid Oxide Fuel Cells (IT-SOFCs) has suggested the study of the system alpha-Al2O3/La-0.8,Sr-0.2,Ga0.8Mg0.2O3-delta as a possible new ionic conductor composite. The studies concerning the electrical and in i micro structural characterization of the system alpha-Al2O3/La0.8Sr0.2Ga0.8Mg0.2O3-delta, in a wide compositions range, are reported and discussed.