1. Importance of molecular typing in confirmation of the source of a national hepatitis A virus outbreak in Norway and the detection of a related cluster in Germany
- Author
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Heidi Lange, Marcus Panning, Line Vold, Karin Nygård, Kathrine Stene-Johansen, Daniela Huzly, Ann Kristin Øye, Katrine Borgen, Mette Myrmel, Solveig Myking, Margot Einöder-Moreno, L Jensvoll, Christoph Neumann-Haefelin, Bernardo Guzman-Herrador, Sigrid Maassen, and Jürgen J. Wenzel
- Subjects
medicine.medical_specialty ,Norway ,Prevalence ,Hepatitis A ,Outbreak ,Food Contamination ,General Medicine ,Biology ,medicine.disease ,Disease cluster ,Virology ,Disease Outbreaks ,Molecular Typing ,Medical microbiology ,Fruit ,Germany ,Epidemiology ,medicine ,Humans ,Hepatitis A virus ,Typing ,Viral hepatitis - Abstract
In March 2014, after an increase of notifications of domestically acquired hepatitis A virus infections, an outbreak investigation was launched in Norway. Sequenced-based typing results showed that these cases were associated with a strain that was identical to one causing an ongoing multinational outbreak in Europe linked to frozen mixed berries. Thirty-three confirmed cases with the outbreak strain were notified in Norway from November 2013 to June 2014. Epidemiological evidence and trace-back investigations linked the outbreak to the consumption of a berry mix cake. Identification of the hepatitis A virus outbreak strain in berries from one of the implicated cakes confirmed the cake to be the source. Subsequently, a cluster in Germany linked to the cake was also identified.
- Published
- 2015
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