16 results on '"Margolles M"'
Search Results
2. Plan de Acción en España para la erradicación de la poliomelitis: Vigilancia de la Parálisis Flácida Aguda y Vigilancia de Enterovirus en España. Informe 2020
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Lopez-Perea, Noemi, Fernandez Martinez, Beatriz, Masa-Calles, Josefa, Cabrerizo Sanz, María, Gallardo, V, Malo, C, Margolles, M, Portell, M, Rojo, ML, Blasco, A, García Hernández, S, Marcos, H, Izquierdo, C, Marín, C, Ramos, JM, Losada, I, Nieto, A, García Ortúzar, V, Alarcón, E, Garcia-Cenoz, Manuel, Arteagoitia, JM, González Carril, Fernando, Martínez-Ochoa, E, Blanco, A, Rivas, A, Castrillejo, D, Limia, A, Sanbonmatsu, S, Navarro, JM, Bordes Benítez, Ana, Pérez-González, C, Rabellà, N, Moreno-Docón, A, Navascués, A, Pérez-Castro, S, Martínez-Sapiña, A, Muñoz-Almagro, C, and Romero, MP
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Poliovirus ,Erradicación de enfermedades ,España ,Poliomelitis ,Parálisis Flácida Aguda ,Enterovirus ,Vigilancia epidemiológica - Abstract
Centro Nacional de Epidemiología y Centro Nacional de Microbiología. ISCIII. Plan de acción en España para la Erradicación de la Poliomielitis. Vigilancia de la Parálisis Flácida Aguda y Vigilancia de Enterovirus en España, Informe año 2020. Madrid, 5 de noviembre de 2021. [ES] En España la situación libre de polio se monitoriza con la vigilancia de Parálisis Flácida Aguda (PFA) en niños menores de 15 años, como recomienda la Organización Mundial de la Salud (OMS). La vigilancia la realizan los servicios de vigilancia autonómicos y la red de laboratorios de PFA y a nivel nacional se coordina en el Centro Nacional de Epidemiología (CNE, ISCIII) y en el Laboratorio de Poliovirus del Centro Nacional de Microbiología (CNM, ISCIII). En el año 2020 en España no hubo casos de poliomielitis. Se notificaron 0,17 casos de PFA por 100.000 niños menores de 15 años, por debajo del objetivo de sensibilidad establecido por la OMS de un caso de PFA al año por cada 100.000 menores de 15 años. Solamente se detectaron enterovirus no-polio (EVNP) en las muestras de dos casos (EV-D68 y EV-B, respectivamente). En España también se realiza la vigilancia de EVNP en otros síndromes neurológicos para complementar el sistema de vigilancia de PFA. En las muestras investigadas en 2020 no se identificó ningún poliovirus y los EVNP más frecuentemente identificados fueron E-18, CV-A6 y E-21. Mientras haya circulación de poliovirus en el mundo hay que mantener activos los sistemas de vigilancia para detectar a tiempo cualquier importación de poliovirus. [EN] Spain monitors its polio-free status by conducting surveillance for cases of acute flaccid paralysis (AFP) in children less than 15 years of age, as recommended by the World Health Organization (WHO). The AFP surveillance is performed by the 19 Regional Epidemiological Surveillance Units and the AFP Surveillance Laboratory Network, coordinated at national level by the National Centre for Epidemiology (CNE. ISCIII) and the National Poliovirus Laboratory at Nacional Center of Microbiology (CNM. ISCIII) respectively. In 2020, no cases of poliomyelitis were reported from clinical surveillance; Spain reported 0.17 non-polio AFP cases per 100,000 children, below the WHO's performance criterion for a sensitive surveillance system (1 non-polio AFP cases per 100,000 children). The non-polio enteroviruses EV-D68, EV-B were identified from clinical specimens collected from AFP cases. Spain also performs enterovirus surveillance to complement the clinical system In 2020, non poliovirus were identified; The non-polioviruses E-18, CV-A6 y E-21 were the most frequently identified serotypes. As long as poliovirus is circulating in the world, surveillance systems must remain active to detect any importation of poliovirus in a timely manner. 1. Resumen. 2. Introducción. 3. Resultados de la vigilancia de Parálisis Flácida Aguda (PFA) en España, 2020. 4. Resultados de la vigilancia de enterovirus, España 2020. 5. Resultados de la vigilancia medioambiental de poliovirus. España, 2020. 6. Sistema de Información Microbiológica (SIM). Meningitis por enterovirus. Tendencia. 7. Conclusiones. No
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- 2021
3. Annual Epidemiological Report: Acute Flaccid Paralysis Surveillance and Enterovirus Surveillance, Spain, 2019
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Lopez-Perea, Noemi, Fernandez Martinez, Beatriz, Masa-Calles, Josefa, Cabrerizo Sanz, María, Gallardo, V, Malo, C, Margolles, M, Portell, M, Rojo, ML, Blasco, A, García Hernández, S, Marcos, H, Torner, N, Gómez, C, Guiral, S, Marín, C, Ramos, JM, Losada, I, Nieto, A, García Ortúzar, V, García Cenoz, M, Arteagoitia, JM, González-Garril, F, Martínez-Ochoa, E, Blanco, A, Rivas, A, Castrillejo, D, Limia, A, Sanbonmatsu, S, Navarro, JM, Pérez-González, C, Rabellà, N, Moreno-Docón, A, Navascués, A, Pérez-Castro, S, Martínez-Sapiña, A, Muñoz-Almagro, C, and Romero, MP
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Poliovirus ,Erradicación de enfermedades ,España ,Poliomelitis ,Parálisis Flácida Aguda ,Enterovirus ,Vigilancia epidemiológica - Abstract
Centro Nacional de Epidemiología y Centro Nacional de Microbiología. ISCIII. Plan de acción en España para la Erradicación de la Poliomielitis. Vigilancia de la Parálisis Flácida Aguda y Vigilancia de Enterovirus en España, año 2019. Madrid, 1 julio 2020. [ES]Los resultados de la vigilancia de parálisis flácida aguda (PFA) y de la vigilancia de enterovirus (EV) muestran que en España en el año 2019 no hubo casos de poliomielitis ni circulación de poliovirus. La sensibilidad del sistema está por debajo del objetivo establecido por la OMS–Europa de 1 caso de PFA al año por cada 100.000 menores de 15 años, al situarse en 0,55/104 hab (0,58/104
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- 2020
4. Prospective multicentre study of rectal carriage of multidrug-resistant Enterobacteriaceae among health-care workers in Spain
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Fernández-Verdugo, A., primary, Forcelledo, L., additional, Rodríguez-Lozano, J., additional, Rodríguez-Lucas, C., additional, Barreiro-Hurlé, L., additional, Canut, A., additional, de la Iglesia, P., additional, Escudero, D., additional, Calvo, J., additional, Boga, J.A., additional, Margolles, M., additional, Rodicio, M.R., additional, and Fernández, J., additional
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- 2020
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5. Beziehungen zwischen Polyaminen und Nucleinsäuren: VII. Versuche zur intrazellulären Lokalisation von Putrescin und Spermidin an gefriergetrockneten und Formaldehydfixierten Kryostatschnitten
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Margolles, M. L. Barros, Fischer, H. A., Seiler, N., and Werner, G.
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- 1973
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6. Mapas de déficits y mapas de activos en prevención de la obesidad infantil
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Cofiño, R., Botello, B., Palacio, S., García, M., Margolles, M., Fernández, F., López, L.M., Gontán, C., Remington, P., and Nieto, J.
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- 2012
7. Mapas de déficits y mapas de activos en prevención de la obesidad infantil
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Cofiño, R., primary, Botello, B., additional, Palacio, S., additional, García, M., additional, Margolles, M., additional, Fernández, F., additional, López, L.M., additional, Gontán, C., additional, Remington, P., additional, and Nieto, J., additional
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- 2012
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8. Factors associated with childhood obesity in Spain. The OBICE study: a case-control study based on sentinel networks.
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Zurriaga O, Pérez-Panadés J, Quiles Izquierdo J, Gil Costa M, Anes Y, Quiñones C, Margolles M, Lopez-Maside A, Vega-Alonso AT, Miralles Espí MT, Recent OBICE Research Group, Zurriaga, Oscar, Pérez-Panadés, Jordi, Quiles Izquierdo, Joan, Gil Costa, Milagros, Anes, Yolanda, Quiñones, Carmen, Margolles, Mario, Lopez-Maside, Aurora, and Vega-Alonso, A Tomás
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PREVENTION of obesity ,DIET ,FOOD habits ,MULTIVARIATE analysis ,OBESITY ,QUESTIONNAIRES ,SELF medication ,LOGISTIC regression analysis ,SOCIOECONOMIC factors ,BODY mass index ,CASE-control method - Abstract
Objective: To estimate the association strength of dietary behaviour and sedentary habits in relation to childhood obesity in Spain.Design: A matched case-control study was carried out using data collected by sentinel network paediatricians in general practices.Setting: Five Spanish autonomous communities.Subjects: Cases were 437 children (2-14 years old) with BMI >95th percentile according to Spanish reference tables. Controls were 751 children (2-14 years old; two paired per case) with BMI <84th percentile. Data were collected in two phases: individual (questionnaires filled in by sentinel paediatricians) and family (self-administered questionnaires filled in a family environment). Crude OR and adjusted OR (ORc and adj OR) for the given variables were calculated using a simple and multiple conditional logistic regression analysis.Results: The factors with the greatest effect on obesity were family history of obesity: both parents (adj OR = 11.2), mother but not father (adj OR = 9.1), father but not mother (adj OR = 6.1), siblings (adj OR = 2.7); and eating between meals (adj OR = 2.5) and consumption of sweets and soft drinks >2 times/week (adj OR = 2.0). The highest protection effect was found for five meals per day (adj OR = 0.5), the regular consumption of breakfast (adj OR = 0.5) and for eating fruit for dessert (adj OR = 0.6). Factors related to sedentary habits did not appear as noteworthy.Conclusions: We have determined the association between certain dietary behaviour and family history with childhood obesity in several Spanish regions. [ABSTRACT FROM AUTHOR]- Published
- 2011
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9. Lifting COVID-19 mitigation measures in Spain (May-June 2020).
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Monge S, Latasa Zamalloa P, Sierra Moros MJ, Pérez Olaso O, García San Miguel L, Varela C, Rivera Ariza S, Vázquez Torres MC, Olmedo Lucerón MDC, González Yuste P, Soler Crespo P, Segura Del Pozo J, Gullón P, Carrasco JM, Martínez Sánchez EV, Redondo Bravo L, Pichiule Castañeda M, Purriños Hermida MJ, Hervada Vidal X, Huerta Gonzalez I, Margolles M, Vanaclocha Luna H, Ramalle Gómara E, Pérez Martín JJ, Chirlaque López MD, López Fernández MJ, Lorusso N, Carmona Ubago A, Rivas Perez A, Ramos Marin V, Criado Alvarez JJ, Castrillejo Pérez D, Góméz Anés AA, Frontera M, Macias Rodriguez P, Álvarez León EE, Díaz Casañas M, Lopaz Perez MA, Alonso Pérez de Ágreda JP, Navas Gutierrez P, Rosell Aguilar I, Arteagoitia Axpe JM, Gonzalez Carril F, Aparicio Azcárraga P, Simón Soria F, and Suarez Rodríguez B
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- Humans, COVID-19 Testing, SARS-CoV-2, Spain epidemiology, COVID-19 epidemiology, COVID-19 prevention & control
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Introduction: The state of alarm was declared in Spain due to the COVID-19 epidemic on March 14, 2020, and established population confinement measures. The objective is to describe the process of lifting these mitigation measures., Methods: The Plan for the Transition to a New Normality, approved on April 28, contained four sequential phases with progressive increase in socio-economic activities and population mobility. In parallel, a new strategy for early diagnosis, surveillance and control was implemented. A bilateral decision mechanism was established between the Spanish Government and the autonomous communities (AC), guided by a set of qualitative and quantitative indicators capturing the epidemiological situation and core capacities. The territorial units were established ad-hoc and could be from Basic Health Zones to entire AC., Results: The process run from May 4 to June 21, 2020. AC implemented plans for reinforcement of core capacities. Incidence decreased from a median (50% of territories) of 7.4 per 100,000 in 7 days at the beginning to 2.5 at the end. Median PCR testing increased from 53% to 89% of suspected cases and PCR total capacity from 4.5 to 9.8 per 1000 inhabitants weekly; positivity rate decreased from 3.5% to 1.8%. Median proportion of cases with traced contacts increased from 82% to 100%., Conclusion: Systematic data collection, analysis, and interterritorial dialogue allowed adequate process control. The epidemiological situation improved but, mostly, the process entailed a great reinforcement of core response capacities nation-wide, under common criteria. Maintaining and further reinforcing capacities remained crucial for responding to future waves., (Copyright © 2021 Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. Published by Elsevier España, S.L.U. All rights reserved.)
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- 2023
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10. Lifting COVID-19 mitigation measures in Spain (May-June 2020).
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Monge S, Zamalloa PL, Moros MJS, Olaso OP, Miguel LGS, Varela C, Ariza SR, Torres MCV, Lucerón MDCO, Yuste PG, Crespo PS, Pozo JSD, Gullón P, Carrasco JM, Sánchez EVM, Bravo LR, Castañeda MP, Hermida MJP, Vidal XH, Gonzalez IH, Margolles M, Luna HV, Gómara ER, Martín JJP, López MDC, Fernández MJL, Lorusso N, Ubago AC, Perez AR, Marin VR, Alvarez JJC, Pérez DC, Anés AAG, Frontera M, Rodriguez PM, León EEÁ, Casañas MD, Perez MAL, Ágreda JPAP, Gutierrez PN, Aguilar IR, Axpe JMA, Carril FG, Azcárraga PA, Soria FS, and Rodríguez BS
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Introduction: The state of alarm was declared in Spain due to the COVID-19 epidemic on March 14, 2020, and established population confinement measures. The objective is to describe the process of lifting these mitigation measures., Methods: The Plan for the Transition to a New Normality, approved on April 28, contained four sequential phases with progressive increase in socio-economic activities and population mobility. In parallel, a new strategy for early diagnosis, surveillance and control was implemented. A bilateral decision mechanism was established between the Spanish Government and the autonomous communities (AC), guided by a set of qualitative and quantitative indicators capturing the epidemiological situation and core capacities. The territorial units were established ad-hoc and could be from Basic Health Zones to entire AC., Results: The process run from May 4 to June 21, 2020. AC implemented plans for reinforcement of core capacities. Incidence decreased from a median (50% of territories) of 7.4 per 100,000 in 7 days at the beginning to 2.5 at the end. Median PCR testing increased from 53% to 89% of suspected cases and PCR total capacity from 4.5 to 9.8 per 1000 inhabitants weekly; positivity rate decreased from 3.5% to 1.8%. Median proportion of cases with traced contacts increased from 82% to 100%., Conclusion: Systematic data collection, analysis, and interterritorial dialogue allowed adequate process control. The epidemiological situation improved but, mostly, the process entailed a great reinforcement of core response capacities nation-wide, under common criteria. Maintaining and further reinforcing capacities remained crucial for responding to future waves., (Copyright © 2021 Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. Publicado por Elsevier España, S.L.U. All rights reserved.)
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- 2021
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11. Acute flaccid paralysis (AFP) surveillance: challenges and opportunities from 18 years' experience, Spain, 1998 to 2015.
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Masa-Calles J, Torner N, López-Perea N, Torres de Mier MV, Fernández-Martínez B, Cabrerizo M, Gallardo-García V, Malo C, Margolles M, Portell M, Abadía N, Blasco A, García-Hernández S, Marcos H, Rabella N, Marín C, Fuentes A, Losada I, Gutiérrez JG, Nieto A, Ortúzar VG, Cenoz MG, Arteagoitia JM, Martínez ÁB, Rivas A, and Castrillejo D
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- Adolescent, Child, Child, Preschool, Disease Eradication, Disease Notification, Female, Humans, Infant, Male, Poliomyelitis epidemiology, Poliomyelitis virology, Spain epidemiology, Disease Outbreaks prevention & control, Paralysis epidemiology, Poliomyelitis prevention & control, Poliovirus isolation & purification, Poliovirus Vaccine, Oral administration & dosage, Poliovirus Vaccines administration & dosage, Population Surveillance methods
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Acute flaccid paralysis (AFP) surveillance is key for global polio eradication. It allows detecting poliovirus (PV) reintroductions from endemic countries. This study describes AFP surveillance in Spain from 1998 to 2015. During this time, 678 AFP cases were reported to the Spanish National Surveillance Network. The mean notification rate was 0.58 AFP cases/100,000 population under 15 years old (range: 0.45/100,000-0.78/100,000). Two periods (P) are described: P1 (1998-2006) with the AFP notification rate ranging from 0.66/100,000 to 0.78/100,000, peaking in 2001 (0.84/100,000); and P2 (2007-2015) when the AFP rate ranged from 0.43/100,000 to 0.57/100,000, with the lowest rate in 2009 (0.31/100,000). No poliomyelitis cases were caused by wild PV infections, although two Sabin-like PVs and one imported vaccine-derived PV-2 were detected. Overall, 23 (3.4%) cases met the hot case definition. Most cases were clinically diagnosed with Guillain-Barré syndrome (76.9%; 504/655). The adequate stool collection rate ranged from 33.3% (7/21) to 72.5% (29/40). The annual proportion of AFP cases with non-polio enterovirus findings varied widely across the study period. AFP surveillance with laboratory testing for non-polio enteroviruses must be maintained and enhanced both to monitor polio eradication and to establish sensitive surveillance for prompt detection of other enteroviruses causing serious symptoms.
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- 2018
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12. Towards a policy relevant neighborhoods and health agenda: engaging citizens, researchers, policy makers and public health professionals. SESPAS Report 2018.
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Franco M, Díez J, Gullón P, Margolles M, Cofiño R, Pasarín M, and Borrell C
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- Humans, Power, Psychological, Research Report, Residence Characteristics, Societies, Medical, Spain, Community Participation, Health Policy, Policy Making, Public Health, Research
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A large volume of public health literature has shown how the social and physical features of a neighbourhood affect residents' health, and how they contribute to health inequalities. In this article, we argue that citizens, researchers, policy makers and health professionals should engage in creating a common, policy-relevant neighbourhood and health agenda to effectively improve population health and reduce health inequalities. We discuss four critical processes for advancing this neighbourhood and health agenda: 1) citizen participation and community empowerment; 2) policy making; 3) producing relevant research; and 4) how to best communicate between stakeholders. Various methodologies and experiences currently exist to secure and promote citizen participation. Sufficient funding of research projects and specific policies, as well as continued communication strategies among stakeholders, are necessary elements of this neighbourhood and health agenda. Establishing collaborative and sustained relationships between citizens, policy makers, health professionals and researchers at local and higher political levels is a challenging but necessary step. Developing participatory action research and local participatory policy efforts are important steps towards developing a policy- relevant neighbourhood and health agenda., (Copyright © 2018 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.)
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- 2018
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13. [Public health surveillance: a pressing need].
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Noguer I, Alonso JP, Arteagoitia JM, Astray J, Cano R, de Pedro J, Gutiérrez G, Hervada X, Margolles M, Nicolau A, Núñez D, Pollán M, Ramos JM, Sierra MJ, and Vanoclocha H
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- Humans, Spain, Public Health Surveillance methods
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- 2017
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14. [Methodology for health assets mapping in a community].
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Botello B, Palacio S, García M, Margolles M, Fernández F, Hernán M, Nieto J, and Cofiño R
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- Humans, Spain, Health Resources organization & administration, Residence Characteristics
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Within the development of a regional strategy for community health engagement in Asturias (Spain), and connected to the Health Observatory, we carried out a methodology to initiate the mapping of health assets at a local level. This methodology begins with a description of the most formal resources and of the pre-existing community activities, together with a characterization of the most informal, personal and symbolic health resources. We introduce our tools, grouped for the development of mapping, and explain their connection with the theoretical models of salutogenesis, asset model and community development., (Copyright © 2012 SESPAS. Published by Elsevier Espana. All rights reserved.)
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- 2013
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15. [Palliative and support care at home in primary care].
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Vega T, Arrieta E, Lozano JE, Miralles M, Anes Y, Gomez C, Quiñones C, Perucha M, Margolles M, Gómez de Caso JÁ, Gil M, Fernández S, de la Iglesia P, López A, Alamo R, Zurriaga O, and Mauro Ramos J
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- Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Diagnosis-Related Groups, Disabled Persons statistics & numerical data, Female, Health Care Surveys, House Calls statistics & numerical data, Humans, Life Expectancy, Male, Middle Aged, National Health Programs, Social Support, Spain, Surveys and Questionnaires, Terminal Care statistics & numerical data, Young Adult, Health Services Needs and Demand statistics & numerical data, Home Care Services statistics & numerical data, Palliative Care statistics & numerical data, Primary Health Care statistics & numerical data
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Objectives: To estimate the proportion of people requiring palliative and support care at home in primary care and to describe their characteristics., Methods: A descriptive study was carried out by five Spanish sentinel networks between October 2007 and March 2008 in 282,216 people attended by 218 general practitioners and nurses. Patients receiving comprehensive, active and continued care at home were included if the aim was not to prolong life but to achieve the best quality of life for the patient, the family and the carers. A standard form was used to collect data on age, sex, type of patient, underlying diseases and other variables related to the process. Crude and age-adjusted rates were estimated., Results: Of the 400 men and 792 women registered, 12% were strictly terminal. The mean age was 82.4 years and was higher in patients with functional disability (82.9 years) than in terminally-ill patients (78.9 years) (p<0.01). The estimated prevalence was 422.3 per 100,000 inhabitants aged 14 years or more (95% CI: 398.7-447.0) and was much higher in women than in men (553.9 versus 287.3, p<0.01). The estimate for the entire Spanish population was 309.0 per 100,000 inhabitants (95% CI: 286.0-332.0)., Conclusions: The prevalence of palliative and support care in Spain is around three cases per 1,000 inhabitants and is higher in elderly populations. More than 85% of patients needing palliative or support care have a life expectancy of over 6 months and thus represent the majority of persons using this type of medical and social support. The most susceptible groups are women and the oldest-old., (Copyright © 2010 SESPAS. Published by Elsevier Espana. All rights reserved.)
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- 2011
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16. [Interrelationships between polyamines and nucleic acids. VII. Study of the intracellular localisation of putrescine and spermidine in freeze-dried and formaldehyde fixed cryostat sections].
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Barros Margolles ML, Fischer HA, Seiler N, and Werner G
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- Animals, Cell Fractionation, Freeze Drying, Histocytochemistry, Lipids, Mice, Nucleic Acids, Proteins, Liver analysis, Putrescine analysis, Spermidine analysis
- Published
- 1973
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