165 results on '"Maresca, Marcello"'
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2. A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo
3. Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing
4. Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi
5. The methylation inhibitor 3DZNep promotes HDR pathway choice during CRISPR-Cas9 genome editing
6. Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq
7. TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis
8. Harnessing DSB repair to promote efficient homology-dependent and -independent prime editing
9. Improved nuclease-based prime editing by DNA repair modulation and pegRNA engineering
10. Universal toxin-based selection for precise genome engineering in human cells
11. Author Correction: Universal toxin-based selection for precise genome engineering in human cells
12. Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements
13. Negative DNA supercoiling induces genome-wide Cas9 off-target activity
14. NKX6.1 induced pluripotent stem cell reporter lines for isolation and analysis of functionally relevant neuronal and pancreas populations
15. Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery
16. Axl receptor tyrosine kinase is a regulator of apolipoprotein E
17. In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model
18. In vivo CRISPR editing with no detectable genome-wide off-target mutations
19. Progress and harmonization of gene editing to treat human diseases:Proceeding of COST Action CA21113 GenE-HumDi
20. Elevated Adipocyte Membrane Phospholipid Saturation Does Not Compromise Insulin Signaling.
21. ELEVATED ADIPOCYTE MEMBRANE PHOSPHOLIPID SATURATION DOES NOT COMPROMISE INSULIN SIGNALING
22. BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B
23. Elevated Adipocyte Membrane Phospholipid Saturation Does not Compromise Insulin Signaling
24. Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing
25. Historical Overview of Genome Editing from Bacteria to Higher Eukaryotes
26. Negative DNA Supercoiling Induces Genome Wide Cas9 Off-Target Activity
27. Harnessing DSB repair to promote efficient homology-dependent and -independent prime editing
28. Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes
29. Universal toxin-based selection for precise genome engineering in human cells
30. High-efficiency counterselection recombineering for site-directed mutagenesis in bacterial artificial chromosomes
31. Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes
32. Extensive transcription mis-regulation and membrane defects in AdipoR2-deficient cells challenged with saturated fatty acids
33. Improving Precise CRISPR Genome Editing by Small Molecules:Is there a Magic Potion?
34. A patient-centric CRISPR-Cas9 in vitro cardiovascular safety model to examine genetic variability in calcium handling and its impact on drug-induced cardiotoxicity
35. Targeted isolation of cloned genomic regions by recombineering for haplotype phasing and isogenic targeting
36. AdipoR2 is Essential for Membrane Lipid Homeostasis in Response to Dietary Saturated Fats
37. Improving Precise CRISPR Genome Editing by Small Molecules: Is there a Magic Potion?
38. ObLiGaRe doxycycline Inducible (ODIn) Cas9 system driving pre-clinical drug discovery, from design to cancer treatment
39. Additional file 8: of In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model
40. Additional file 1: of In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model
41. Additional file 7: of In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model
42. Additional file 6: of In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model
43. Additional file 9: of In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model
44. Additional file 3: of In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model
45. Additional file 5: of In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model
46. Additional file 2: of In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model
47. Additional file 1: of BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B
48. A CRISP(e)R view on kidney organoids allows generation of an induced pluripotent stem cell–derived kidney model for drug discovery
49. Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq
50. Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived Neurons
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