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High-speed dynamic centrifugal compressors are widely used both in the modern internal combustion engine design and in advanced pressurized cycles and innovative plant layouts as fuel cell systems. Surge strongly limits the stable operating region of centrifugal compressors in low mass flow rate conditions especially during fast transients. Therefore, it is of great importance to investigate transient system dynamic response of compressor surge evolution and early detection of incipient compressor surge. A specific experimental investigation on compressor surge was carried out at the University of Genoa turbocharger test facility and results are presented and analysed in this paper. The activity consists of steady state and transient measurements used to characterize and identify compressor behaviour in correspondence of surge inception conditions. The frequency and time frequency data analysis have been applied on inflow pressure, anemometric and vibrational signals to identify their contents and so to be able to classify compressor operation as stable or unstable. Synchronous averages performed in the time domain have been identified as a suitable algorithmic tool to detect incipient surge conditions. Anemometric signal analysis allowed to identify intermitting phenomena in deep surge conditions may be related to the rise of a rotation stall condition. The obtained results provide original diagnostic and predictive methods to be integrated in a monitoring system capable of preventing surge and extending compressor operating range, performance and reliability to allow the integration with the other plant components.

The reduction of CO2 and, more generally, GHG (Green House Gases) emissions imposed by the European Commission (EC) and the Environmental Protection Agency (EPA) for passenger cars has driven the automotive industry to develop technological solutions to limit exhaust emissions and fuel consumption, without compromising vehicle performance and drivability. In a mid-term scenario, hybrid powertrain and Internal Combustion Engine (ICE) downsizing represent the present trend in vehicle technology to reduce fuel consumption and CO2 emissions. Concerning downsizing concept, to maintain a reasonable power level in small engines, the application of turbocharging is mandatory for both Spark Ignition (SI) and Diesel engines. Following this aspect, the possibility to recover the residual energy of the exhaust gases is becoming more and more attractive, as demonstrated by several studies around the world. One method to recover exhaust gas energy from ICEs is the adoption of turbo-compounding technology to recover sensible energy left in the exhaust gas by-passed through the waste-gate valve. In the paper, an innovative option of advanced boosting system is investigated through a bladeless micro expander, promising attractive cost-competitiveness. The numerical activity was developed on the basis of experimental data measured on a waste-gated turbocharger for downsized SI automotive engines. To this aim, mass flow rate through the by-pass valve and the turbine impeller was measured for different waste-gate settings in steady-state conditions at the turbocharger test bench of the University of Genoa. The paper shows that significant electrical power can be harvested from the waste-gate gases, up to 94 % of compressor power, contributing to fuel consumption reduction.

Abstract Background For many women finding the right contraceptive method can be challenging and consistent and correct use over a lifetime is difficult. Even remembering to take a birth control pill every day can be a challenge. The primary objective of this study was to evaluate women's experience with a weekly ethinylestradiol/norelgestromin contraceptive patch (EE/NGMN patch), given new technologies recently developed in hormonal contraception to increase women's options in avoiding daily dosing. Methods In 24 Italian sites, 207 women received the EE/NGMN patch for up to 6 cycles. At study end, overall satisfaction and preference, as well as compliance, efficacy and safety, were evaluated. Results 175 women (84.5%) completed the study. The overall satisfaction rate was 88%; convenience and once-a-week frequency of the patch were especially appreciated. At baseline, 82 women (39.4%) were using a contraceptive method, mainly oral contraceptives and barrier methods, but only 45.1% were very satisfied/satisfied; after 6 months with the patch, 86.3% of this subset was very satisfied/satisfied. Considering the method used in the 3 months before the study entry, 78.1% strongly preferred/preferred the patch, for convenience (53.9%), ease of use/simplicity (28.9%), fewer (9.2%) and less severe (2.6%) side effects. Compliance was very high: 1034/1110 cycles (93.2%) were completed with perfect compliance and the mean subject's compliance score was 90%. One on-therapy pregnancy occurred. The patch was safe and well tolerated: adverse events frequency was low, with predominantly single reports of each event. Most of them started and subsided during cycle 1. Conclusion This study demonstrated that the EE/NGMN patch is associated with high satisfaction levels and excellent compliance. At study end, the majority of women indicated that they would continue using the patch.

Abstract Background As weight gain is one of the most frequently cited reasons for not using and for discontinuing hormonal contraceptives, in an open-label, single-arm, multicentre clinical study we evaluated the effect of the ethinylestradiol/norelgestromin contraceptive patch (EVRA, Janssen-Cilag International, Belgium) on body composition using bioelectrical impedance analysis (BIA). Methods Body weight and impedance vector components (resistance (R) and reactance (Xc), at 50 kHz frequency, Akern-RJL Systems analyzer) were recorded before entry, after 1, 3 and 6 months in 182 Italian healthy women aged 29 yr (18 to 45), and with BMI 21.8 kg/m2 (16 to 31). Total body water (TBW) was estimated with a BIA regression equation. Vector BIA was performed with the RXc mean graph method and the Hotelling's T2 test for paired and unpaired data. Results After 6 months body weight increased by 0.64 kg (1.1%) and TBW increased by 0.51 L (1.7%). The pattern of impedance vector displacement indicated a small increase in soft tissue hydration (interstitial gel fluid). Body composition changes did not significantly differ among groups of previous contraceptive methods. Arterial blood pressure did not significantly change over time. Conclusion After 6 months of treatment with the ethinylestradiol/norelgestromin contraceptive patch we found a minimal, clinically not relevant, increase in body weight less than 1 kg that could be attributed to an adaptive interstitial gel hydration. This fluctuation is physiological as confirmed by the lack of any effect on blood pressure. This could be useful in increasing women's choice, acceptability and compliance of the ethinylestradiol/norelgestromin contraceptive patch.

Due to the increasingly restrictive limits of pollutant emissions, electrification of automotive engines is now mandatory. For this reason, adopting hybrid boosting systems to improve brake specific fuel consumption and time-to-boost is becoming common practice. In this paper an advanced turbocharging system is analyzed, consisting in an electrically assisted radial compressor and a traditional turbocharger. As a first step, the steady-state performance of each component was measured at the University of Genoa test rig. Subsequently another experimental campaign was carried out to evaluate the transient response of the entire turbocharging system. Two different layouts were compared: upstream and downstream. In the upstream configuration the electrically assisted compressor was placed in front of the traditional turbocharger, in the downstream configuration the e-compressor was positioned after the traditional turbocharger. The two different coupling configurations, upstream and downstream, were then modeled in 1-D simulation software following the dimensions and characteristics of the experimental line from which the exploited data originates. The models were first validated by emulating the steady-state condition and subsequently the transient response was simulated and analyzed. Secondly, the transient response of the two layouts was compared, removing the constraints imposed by the experimental activity. The practical significance of the results is outlined, with reference to the transient response of the turbocharger. The adoption of the boosting system presented here allows a fast and stable transient response. Moreover, a reduction in the engine back pressure could be achieved through an optimization of the boosting system-engine matching calculation. [ABSTRACT FROM AUTHOR]