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261 results on '"Marciano E"'

5. T.02.6 EFFECTIVENESS OF VERY LOW-VOLUME PREPARATION FOR COLONOSCOPY IN HOSPITALIZED OLDER PATIENTS: SINGLE CENTER OBSERVATIONAL TRIAL

Author

Ovidi, F., primary, Solinas, I., additional, Bolognesi, V., additional, Visaggi, P., additional, Tapete, G., additional, Adamo, G., additional, Bellini, M., additional, Gambaccini, D., additional, Natali, V., additional, Tarducci, L., additional, Marciano, E., additional, Fuccio, L., additional, Savarino, E.V., additional, and De Bortoli, N., additional

Published
2023
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6. Regret affects the choice between neoadjuvant therapy and upfront surgery for potentially resectable pancreatic cancer

Author

Cucchetti, A., Djulbegovic, B., Crippa, S., Hozo, I., Sbrancia, M., Tsalatsanis, A., Binda, C., Fabbri, C., Salvia, R., Falconi, M., Ercolani, G., Alfieri, Sergio, Amato, A., Amisano, M., Anderloni, A., Maestri, A., Coluccio, C., Brandi, G., Casadei-Gardini, A., Cennamo, V., Crino, S. F., Valle, R. D., De Angelis, C., Di Battista, M., Di Maio, M., Di Marco, M., Di Matteo, F., Di Mitri, R., Ettorre, G. M., Facciorusso, A., Farina, G., Ferrari, G., Fornaro, L., Frigerio, I., Frisone, D., Fuccio, L., Gardini, A., Garufi, C., Giampieri, R., Grazi, G. L., Jovine, E., Kauffmann, E., Langella, S., Larghi, Alberto Leonardo, Manno, M., Marciano, E., Marzioni, M., Merighi, A., Mutignani, M., Nardo, B., Niger, M., Palmisano, V., Partelli, S., Pinto, C., Piras, E., Rapposelli, I. G., Reni, M., Ricci, C., Rimassa, L., Siena, S., Spada, Cristiano, Sperti, E., Spezzaferro, M., Sposito, C., Tamberi, S., Troisi, R., Veneroni, L., Vivarelli, M., Zerbi, A., Alfieri S. (ORCID:0000-0002-0404-724X), Larghi A., Spada C. (ORCID:0000-0002-5692-0960), Cucchetti, A., Djulbegovic, B., Crippa, S., Hozo, I., Sbrancia, M., Tsalatsanis, A., Binda, C., Fabbri, C., Salvia, R., Falconi, M., Ercolani, G., Alfieri, Sergio, Amato, A., Amisano, M., Anderloni, A., Maestri, A., Coluccio, C., Brandi, G., Casadei-Gardini, A., Cennamo, V., Crino, S. F., Valle, R. D., De Angelis, C., Di Battista, M., Di Maio, M., Di Marco, M., Di Matteo, F., Di Mitri, R., Ettorre, G. M., Facciorusso, A., Farina, G., Ferrari, G., Fornaro, L., Frigerio, I., Frisone, D., Fuccio, L., Gardini, A., Garufi, C., Giampieri, R., Grazi, G. L., Jovine, E., Kauffmann, E., Langella, S., Larghi, Alberto Leonardo, Manno, M., Marciano, E., Marzioni, M., Merighi, A., Mutignani, M., Nardo, B., Niger, M., Palmisano, V., Partelli, S., Pinto, C., Piras, E., Rapposelli, I. G., Reni, M., Ricci, C., Rimassa, L., Siena, S., Spada, Cristiano, Sperti, E., Spezzaferro, M., Sposito, C., Tamberi, S., Troisi, R., Veneroni, L., Vivarelli, M., Zerbi, A., Alfieri S. (ORCID:0000-0002-0404-724X), Larghi A., and Spada C. (ORCID:0000-0002-5692-0960)

Abstract

Background: When treating potentially resectable pancreatic adenocarcinoma, therapeutic decisions are left to the sensibility of treating clinicians who, faced with a decision that post hoc can be proven wrong, may feel a sense of regret that they want to avoid. A regret-based decision model was applied to evaluate attitudes to-ward neoadjuvant therapy versus upfront surgery for potentially resectable pancreatic adenocarcinoma.Methods: Three clinical scenarios describing high-, intermediate-, and low-risk disease-specific mortality after upfront surgery were presented to 60 respondents (20 oncologists, 20 gastroenterologists, and 20 surgeons). Respondents were asked to report their regret of omission and commission regarding neo-adjuvant chemotherapy on a scale between 0 (no regret) and 100 (maximum regret). The threshold model and a multilevel mixed regression were applied to analyze respondents' attitudes toward neo-adjuvant therapy.Results: The lowest regret of omission was elicited in the low-risk scenario, and the highest regret in the high-risk scenario (P < .001). The regret of the commission was diametrically opposite to the regret of omission (P < .001). The disease-specific threshold mortality at which upfront surgery is favored over the neoadjuvant therapy progressively decreased from the low-risk to the high-risk scenarios (P <=.001). The nonsurgeons working in or with lower surgical volume centers (P = .010) and surgeons (P = .018) accepted higher disease-specific mortality after upfront surgery, which resulted in the lower likelihood of adopting neoadjuvant therapy.Conclusion: Regret drives decision making in the management of pancreatic adenocarcinoma. Being a surgeon or a specialist working in surgical centers with lower patient volumes reduces the likelihood of recommending neoadjuvant therapy.(c) 2023 Elsevier Inc. All rights reserved.

Published
2023

7. Microbiological surveillance post-reprocessing of flexible endoscopes used in digestive endoscopy: a national study

Author

Casini, B., primary, Spagnolo, A.M., additional, Sartini, M., additional, Tuvo, B., additional, Scarpaci, M., additional, Barchitta, M., additional, Pan, A., additional, Agodi, A., additional, Cristina, M.L., additional, Baroncelli, L., additional, Castiglia, P., additional, De Giusti, M., additional, Distefano, M.M., additional, Longhitano, A.M., additional, Laganà, P., additional, Mentore, B., additional, Canale, F., additional, Mantero, F., additional, Opezzi, M., additional, Marciano, E., additional, Zurlo, L., additional, Segata, A., additional, Torre, I., additional, Vay, D., additional, Vecchi, E., additional, and Vincenti, S., additional

Published
2023
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16. Correlazione genetica nei DSA

Author

Malesci R, Laria C, Monzillo C, Marciano E, Franzè Annamaria, Malesci, R, Laria, C, Monzillo, C, Marciano, E, and Franzè, Annamaria

Published
2019

26. Effect of the first language on spanish learners’ production of english embedded interrogative clauses

Author

Marciano Escutia

Subjects
grammatical competence, embedded indirect questions, minimalist program, native and non-native language acquisition, Philology. Linguistics, P1-1091
Abstract

This paper tries to articulate from the point of view of linguistic theory how Spanish native grammatical competence of embedded indirect questions, as characterized by the Minimalist Program (Chomsky, 1995), can influence knowledge and production of such structures in non-native English by adult Spanish learners. A theory on the difference between native and adult non-native acquisition is also invoked in order to support the need for explicitly teaching and making adult learners aware of the differences between the two languages for these particular structures.

Published
2023

27. P.08.24 EUS-FNA WET-TECHNIQUE IN 31 SOLID PANCREATIC LESIONS: PISA EXPERIENCE

Author

Gambaccini, D., primary, Fabbri, C., additional, Russo, S., additional, Campani, D., additional, Fani, B., additional, Giannotti, S., additional, Natali, V., additional, Luglio, G., additional, Grilli, M., additional, Sansotta, L., additional, Giovanelli, S., additional, Bellini, M., additional, Marchi, S., additional, Bresci, G., additional, and Marciano, E., additional

Published
2018
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29. The rs39335 polymorphism of the RELN gene is not associated with otosclerosis in a southern Italian population

Author

Iossa S, Corvino V, Giannini P, Salvato R, Cavaliere M, Panetti M, Panetti G, Piantedosi B, Marciano E, Franzè A., Iossa, S, Corvino, V, Giannini, P, Salvato, R, Cavaliere, Michele, Panetti, M, Panetti, G, Piantedosi, B, Marciano, Elio, and Franze', Annamaria

Subjects
Otosclerosi, RELN gene, Adult, Male, Extracellular Matrix Proteins, Cell Adhesion Molecules, Neuronal, Serine Endopeptidases, Otology, Nerve Tissue Proteins, Middle Aged, Polymorphism, Single Nucleotide, Single nucleotide polymorphism, Reelin Protein, Otosclerosis, Italy, Case-Control Studies, Humans, Female, rs39335
Abstract

Otosclerosis, the single most common cause of hearing impairment in white adults, is characterised by bone dystrophy localized to the otic capsule and isolated endochondral bone sclerosis with alternating phases of bone resorption and formation. Conductive hearing loss develops when otosclerotic foci invade the stapedio-vestibular joint (oval window) and interfere with free motion of the stapes, but affected subjects frequently develop profound sensorineural hearing loss. The aetiology of otosclerosis is unknown. In the last years, several association studies have been performed and have suggested that single nucleotide polymorphisms in some genes may be implicated in development of otosclerosis. The strongest association has been demonstrated for the reelin gene, located on chromosome 7q22.1, which encodes an extracellular matrix protein. The involvement of reelin in the pathogenesis of otosclerosis is controversial; it was identified in European and North African populations, but was excluded in an Indian population. To analyze the role of reelin in otosclerosis, it has been studied in a case-control analysis for the polymorphism rs39335 in a southern Italy population. In this population, the pathogenic link between the rs39335 variant and otosclerosis was excluded.L'otosclerosi, la causa più comune di perdita uditiva tra gli adulti bianchi, è caratterizzata da distrofia ossea localizzata alla capsula otica e sclerosi ossea encondrale isolata con alternanza di fasi di riassorbimento e formazione dell'osso. L'ipoacusia trasmissiva si sviluppa quando i focolai otosclerotici invadono l'articolazione stapedio-ovalare (finestra ovale) ed interferiscono con il libero movimento della staffa, ma spesso i soggetti affetti sviluppano un'ipoacusia neurosensoriale profonda. Ad oggi, l'eziologia dell'otosclerosi non è ancora nota. Negli ultimi anni, studi di associazione di diversi polimorfismi sono stati eseguiti e hanno suggerito il coinvolgimento di alcuni di essi nell'insorgenza dell'otosclerosi. L'associazione più forte è stata dimostrata per il gene relina, localizzato sul cromosoma 7q22.1 codificante una proteina della matrice extracellulare. Il coinvolgimento di relina nella patogenesi dell'otosclerosi è controverso in quanto è stato identificato in alcune popolazioni Europee e del Nord Africa, ma è stato escluso nella popolazione Indiana. Per analizzare l'importanza di relina nell'otosclerosi è stato realizzato uno studio di associazione caso-controllo per il polimorfismo rs39335 in una popolazione del Sud Italia. In questa popolazione l'associazione del polimorfismo rs9335 nello sviluppo dell'otosclerosi è stata esclusa.

Published
2013

35. GASTRECTOMIA SUBTOTALE FULL-ROBOTIC

Author

Morelli, Luca, Pisano, Roberta, Guadagni, Simone, Palmeri, Matteo, Baglioni, M, D'Isidoro, Cristiano, Caprili, G, Gremmo, F, Marciano, E, DI CANDIO, Giulio, and Mosca, Franco

Published
2014

38. Otosclerosis: exclusion of linkage to the OTSC1 and OTSC2 loci in four Italian families

Author

Di Leva, F., Adamo Pio d'Adamo, Strollo, L., Auletta, G., Caravelli, A., Carella, M., Mari, F., Livi, W., Renieri, A., Gasparini, P., D Urso, M., Marciano, E., Franzé, A., Di Leva, F, D'Adamo, Ap, Strollo, L, Auletta, G, Caravelli, A, Carella, M, Mari, F, Livi, W, Renieri, A, Gasparini, P, D'Urso, M, Marciano, Elio, Franze', Annamaria, DI LEVA, F, D'Adamo, ADAMO PIO, Gasparini, Paolo, Marciano, E, and Franze, A.

Subjects
Male, Otosclerosi, Genotype, Linkage, Genetic Linkage, Pedigree, Otosclerosis, Acoustic Impedance Tests, Italy, Audiometry, Pure-Tone, Humans, Female, OTSC2, Lod Score, OTSC1, hearing loss
Abstract

Otosclerosis is the single most common cause of hearing impairment among adult caucasians. Little is known about its aetiology and its molecular aspects. Until now, genetic linkage in otosclerosis has been demonstrated in an Indian family and a Belgian family, showing the presence of two otosclerosis loci, OTSC1 and OTSC2, respectively. Linkage analysis has never been applied to Italian otosclerotic families. We have collected four multigenerational Italian otosclerotic families that show dominant transmission for the pathology. Here, we report a detailed audiological analysis of these families and a genetic linkage study on the OTSC1 and OTSC2 loci. Statistical analysis revealed the absence of linkage between the disease in our families and the OTSC1 and OTSC2 loci. These data strongly suggest the presence of one or more additional loci for otosclerosis, which still need to be defined.

Published
2003

43. Five-Years Experience of Robotic Vs Laparoscopic Colorectal Cancer Surgery in a Single Center: Surgical Parameters and Costs

Author

Morelli, L, primary, Cobuccio, L, additional, Lorenzoni, V, additional, Guadagni, S, additional, Palmeri, M, additional, Di Franco, G, additional, Gennai, A, additional, Caprili, G, additional, D’Isidoro, C, additional, Marciano, E, additional, Di Candio, G, additional, Mosca, F, additional, and Turchetti, G, additional

Published
2015
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