Search

Serous peritoneal and high‐grade serous ovarian/tubal cancers are treated identically with maximal cytoreductive surgery and platinum‐based chemotherapy. Here, we provide epidemiological, clinical, and molecular evidence that peritoneal cancer is more aggressive and shows a distinct molecular signature on gene and protein levels. Our data suggest alternative treatment decisions and to consider the tumor‐sampling site for diagnosis in the future., In the era of personalized medicine, where transition from organ‐based to individualized genetic diagnosis takes place, the tailoring of treatment in cancer becomes increasingly important. This is particularly true for high‐grade, advanced FIGO stage serous adenocarcinomas of the ovary (OC), fallopian tube (TC), and peritoneum (PC), which are currently all treated identically. We analyzed three independent patient cohorts using histopathologically classified diagnosis and various molecular approaches (transcriptomics, immunohistochemistry, next‐generation sequencing, fluorescent and chromogenic in situ hybridization). Using multivariate Cox regression model, we found that PC is more aggressive compared with advanced‐stage OC independent of residual disease as shown by an earlier relapse‐free survival in two large cohorts (HR: 2.63, CI: 1.59–4.37, P

This document presents the minimal requirements for measurement and validation of biochemical methane potential (also called biomethane potential)(BMP) in batch tests, and represents the consensus of more than 40 biogas researchers. The list of requirements is based on Holliger et al.[2016], with some recent modifications of validation criteria as described in Hafner et al.[2020c] and additional details on calculation standardization.

Les espèces et la fréquence d'isolement des levures associées à la pourriture acide ont été determinées. Les genres les plus fréquemment isolés ont été Candida, Pichia et Hanseniaspora, qui sont à même de reproduire in vivo les symptômes de la maladie. Néanmoins d'autres espèces, bien que moins fréquentes, se sont révélées être capables de provoquer la pourriture acide in vitro et de reproduire des profils GLC des composants volatils de l'espace de tête très semblables à ceux des grappes infectées naturellement. Les activités enzymatiques extracellulaires lytiques et leur fréquence dans la population des levures isolées sur les raisins pourris ont été étudiées. Research on the etiology of a new disease of grapes: sour rot The species of the yeasts associated with sour rot and the frequency of their isolation were determined. The most frequent genera were Candida, Pichia and Hanseniaspora. Species belonging to these genera were able to induce the symptoms of the disease in vivo when inoculated into table grapes. However, other species less frequent have also been found able to induce the rot in vitro and to reproduce GLC profiles of volatile compounds of head space very similar to those of naturally infected grapes. The extracellular lytic enzyme activity of isolated strains and their frequency in the population of infected grapes were studied., VITIS - Journal of Grapevine Research, Vol. 23 No. 1 (1984): Vitis

Biofumigant crops used as green manure, in addition to producing a biocidal effect on some soil-borne pathogens and pests, could represent a source of N for crop nutrition. In two laboratory experiments we compared i) the potentially mineralizable N (PMN) of a silty clay soil after incorporation of glucosinolate-containing (GLS+) and non-containing (GLS–) plants, or after incorporation of metam sodium; and ii) the mineralization rate of different types of soils (silty clay, loam and loamy sand) after green manuring with GLS+ crops. After a 3-month incubation, the PMN of the silty clay soil amended with the GLS+ Brassica juncea was significantly higher than the unamended control and the soil amended with Triticum aestivum and Eruca sativa. Metham sodium, while showing a remarkable nitrification inhibition activity, gave rise to amounts of inorganic N (mainly in the ammonium form) of the same level as B. juncea. Mineralization rate was higher in the loamy sand soil than in the loam and in the silty clay soils. Biofumigant crops used as green manure, by increasing N availability in soil, may represent an interesting source of N for the following crops in organic agriculture.

The knowledge of the dynamics of inorganic N in soil may help to establish the most suitable timing for green manure (GM) incorporation, which leads to the improvement of crop N use efficiency in conventional as well as organic agriculture. The practice of green manuring with crop species belonging to the Brassicaceae family has recently expanded, in Italy and abroad, due to their demonstrated biocidal effect against soil-borne pathogens. In this plot-scale study we monitored the release of soil inorganic N in 3 soil types (1 clay and 2 loams), in the months following late-spring green manuring with plant material from Brassica juncea, Sinapis alba, and Raphanus sativus species. Soil inorganic N content increased and reached a maximum 2 months after GM incorporation (+14.4 mg N kg1 dry soil, on average, over the initial inorganic N content), and subsequently declined. The inorganic N accumulation was higher in soil amended with R. sativus. We did not observe any significant influence of the soil type on the variation of inorganic N content in the period after GM incorporation. The inorganic N released after late-spring green manuring with Brassicaceae species may become available in the early growth phase of subsequent summer-autumn crops.