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2. List of Contributors

Author

Abboud, Olivier, primary, Abdullah, Victor James, additional, Ahmad, Zahoor, additional, Al-Qurayshi, Zaid, additional, Athwal, Harleen K., additional, Bacon, Alfred E., additional, Balzer, Bonnie Lei, additional, Bell, Diana, additional, Bradley, Patrick James, additional, Brito-Zerón, Pilar, additional, Cernea, Claudio R., additional, Chan, Jason YK, additional, Chaplin, John M., additional, Cheong, Crystal Shuk Jin, additional, Chien, Chih-Yen, additional, Chossegros, Cyrille, additional, Chuang, Hui-Ching, additional, Clarke, Raymond William, additional, Cognetti, David M., additional, Dam, Hung, additional, Deschler, Daniel, additional, Dias, Fernando L., additional, Do, Kevin Oshiro, additional, Dulguerov, Pavel, additional, Eisele, David W., additional, Fagan, Johannes J., additional, Farach-Carson, Mary C., additional, Farina, Davide, additional, Faure, Frederic, additional, Ferrarotto, Renata, additional, Flores-Chavez, Alejandra, additional, Foletti, Jean Marc, additional, Freiser, Monika E., additional, Gandhi, Arpit, additional, Gasalberti, David, additional, Geisthoff, Urban, additional, Gillespie, M. Boyd, additional, Graillon, Nicolas, additional, Hammon, Rebecca J., additional, Hao, Chung-Yu, additional, Hao, Sheng-Po, additional, Harrington, Daniel A., additional, Harrison, John D., additional, Hoffman, Henry T., additional, Iaia, Alberto, additional, Ihrler, Stephan, additional, Iro, Heinrich, additional, Irvine, Robert A., additional, Kahane, Jacob, additional, Zanoni, Daniella Karassawa, additional, Kim, Kwang Hyun, additional, Klein, Hila, additional, Koch, Michael, additional, Lai, Nelson Kwong Lun, additional, Lancini, Davide, additional, Larian, Babak, additional, Lau, Thomas Kwan Hang, additional, Laughlin, Brady, additional, Le Roux, Marc-Kevin, additional, Lee, Doh Young, additional, Lee Kun Min, Mimi, additional, Li, Hok Nam, additional, Lima, Roberto A., additional, Loh, Thomas K.S., additional, Loh, Woei-Shyang, additional, Lombaert, Isabelle M.A., additional, Lombardi, Davide, additional, Lopez, Jean-Michel, additional, Mantsopoulos, Konstantinos, additional, Marchal, Francis, additional, McGurk, Mark, additional, Meyeroff, Joshua H., additional, Morton, Randall P., additional, Myers, Eugene Nicholas, additional, Nahlieli, Oded, additional, Ng, Siu-Kwan, additional, Nicolai, Piero, additional, O'Malley, Bert W., additional, Palhazi, Peter, additional, Park, SuJung, additional, Pasche, Philippe, additional, Patel, Snehal G., additional, Peterson, Joseph D., additional, Polselli, Roberto, additional, Pouzoulet, Pauline, additional, Pradhan-Bhatt, Swati, additional, Raben, Adam, additional, Ramos-Casals, Manuel, additional, Rassekh, Christopher H., additional, Reeve, Nathaniel, additional, Retamozo, Soledad, additional, Santos, Jorge Rosa, additional, Saban, Yves, additional, Sagiv, Doron, additional, Samant, Sumit, additional, Schaitkin, Barry M., additional, Sözen, Tevfik, additional, Srinivasan, Padma Pradeepa, additional, Strenger, Tobias, additional, Su, Shirley Y., additional, Tae, Kyung, additional, Talmi, Yoav P., additional, Tomasoni, Michele, additional, Poorten, Vincent Vander, additional, Walvekar, Rohan R., additional, Wang, Jennifer R., additional, Wang, Robert C., additional, Weber, Randal S., additional, Weinstein, Gregory S., additional, Wong, Eddy WY, additional, Wong, Priscilla Ching-han, additional, Zbären, Peter, additional, Zenga, Joseph, additional, and Zenk, Johannes, additional

Published
2021
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6. Liste des collaborateurs

Author

Astudillo, Leonardo, primary, Aussedat, Charles, additional, Ayari, Sonia, additional, Bailleux, Sonanda, additional, Barry, Béatrix, additional, Benoudiba, Farida, additional, Bensadoun, René-Jean, additional, Bigorgne, Claude, additional, Bonnecaze, Guillaume de, additional, Cartier, César, additional, Chevalier, Dominique, additional, Costes-Martineau, Valérie, additional, Coudert, Aurélie, additional, Courtade-Saïdi, Monique, additional, Espinoza, Sophie, additional, Fakhry, Nicolas, additional, Faure, Frédéric, additional, Fayoux, Pierre, additional, Ferrand, François-Régis, additional, Gallet, Patrice, additional, Garrel, Renaud, additional, Jegoux, Franck, additional, Kennel, Thibault, additional, Guily, Jean Lacau Saint, additional, Lallemant, Benjamin, additional, Leboulanger, Nicolas, additional, Leclère, Jean-Christophe, additional, Lopez, Jean-Michel, additional, Boudrigua, Aïcha LTaief, additional, Mailly, Marie, additional, Makeieff, Marc, additional, Malard, Olivier, additional, Marchal, Francis, additional, Marianowski, Rémi, additional, Mattei, Pierre, additional, Mogultay, Pierre, additional, Monès del Pujol, Erwan de, additional, Moreddu, Éric, additional, Morinière, Sylvain, additional, Nicollas, Richard, additional, Prades, Jean-Michel, additional, Regnier, Gaëlle, additional, Righini, Christian-Adrien, additional, Rome, Angélique, additional, Thariat, Juliette, additional, Troussier, Idriss, additional, Uro-Coste, Emmanuelle, additional, Varoquaux, Arthur, additional, and Vergez, Sébastien, additional

Published
2020
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18. The RAI-6 Questionnaire: A New Screening Questionnaire to Monitor Complications of Radioiodine Treatment

Author

Buchholzer, Samanta, primary, Thakachy Subha, Sethu, additional, Tchérémissinoff, Livia, additional, Boselie, Franciscus, additional, Triponez, Frédéric, additional, Faure, Frédéric, additional, Lopez, Jean-Michel, additional, Borner, Urs, additional, Kleinjung, Tobias, additional, Seebach, Jörg D., additional, Dulguerov, Pavel, additional, and Marchal, Francis, additional

Published
2021
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19. Novel Multidisciplinary Salivary Gland Society ( MSGS ) Questionnaire: An International Consensus

Author

Buchholzer, Samanta, primary, Faure, Frédéric, additional, Tcheremissinoff, Livia, additional, Herrmann, François R., additional, Lombardi, Tommaso, additional, Ng, Siu‐Kwan, additional, Lopez, Jean‐Michel, additional, Borner, Urs, additional, Witt, Robert L., additional, Irvine, Robert, additional, Abboud, Olivier, additional, Cernea, Claudio R., additional, Ghan, Shirish, additional, Matsunobu, Takeshi, additional, Ahmad, Zahoor, additional, Morton, Randall, additional, Anicin, Aleksandar, additional, Magdy, Emad A., additional, Al Abri, Rashid, additional, Konstantinidis, Iordanis, additional, Capaccio, Pasquale, additional, Klein, Hila, additional, Poorten, Vincent Vander, additional, Lombardi, Davide, additional, Lyons, Bernard, additional, Al Rand, Hussain, additional, Liao, George, additional, Kim, Jeong K., additional, Subha, Sethu, additional, Su, Richard Y.‐X., additional, Su, Chin‐Hui, additional, Boselie, Franciscus, additional, Andre, Raphaël, additional, Seebach, Jörg D., additional, and Marchal, Francis, additional

Published
2021
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21. Novel Multidisciplinary Salivary Gland Society (MSGS) questionnaire: an international consensus

Author

Buchholzer, Samanta, Faure, Frédéric, Tchérémissinoff, Livia, Herrmann, François R., Lombardi, Tommaso, Siu, Kwan Ng, Lopez, Jean-Michel, Borner, Urs, Witt, Robert L., Irvine, Robert, Abboud, Olivier, Cernea, Claudio R., Ghan, Shirish, Matsunobu, Takeshi, Ahmad, Zahoor, Morton, Randall, Anicin, Aleksandar, Magdy, Emad A., Al Abri, Rashid, Konstantinidis, Iordanis, Capaccio, Pasquale, Klein, Hila, Poorten, Vincent Vander, Lombardi, Davide, Lyons, Bernard, Al Rand, Hussain, Liao, George, Jeong, K. Kim, Subha, Sethu, Su, Richard Y.-X., Chin, Hui Su, Boselie, Franciscus, Andre, Raphaël, Seebach, Jörg D., Marchal, Francis, Buchholzer, Samanta, Faure, Frédéric, Tchérémissinoff, Livia, Herrmann, François R., Lombardi, Tommaso, Siu, Kwan Ng, Lopez, Jean-Michel, Borner, Urs, Witt, Robert L., Irvine, Robert, Abboud, Olivier, Cernea, Claudio R., Ghan, Shirish, Matsunobu, Takeshi, Ahmad, Zahoor, Morton, Randall, Anicin, Aleksandar, Magdy, Emad A., Al Abri, Rashid, Konstantinidis, Iordanis, Capaccio, Pasquale, Klein, Hila, Poorten, Vincent Vander, Lombardi, Davide, Lyons, Bernard, Al Rand, Hussain, Liao, George, Jeong, K. Kim, Subha, Sethu, Su, Richard Y.-X., Chin, Hui Su, Boselie, Franciscus, Andre, Raphaël, Seebach, Jörg D., and Marchal, Francis

Abstract

Objectives: First, establishment and validation of a novel questionnaire documenting the burden of xerostomia and sialadenitis symptoms, including quality of life. Second, to compare two versions regarding the answering scale (proposed developed answers Q3 vs. 0–10 visual analogue scale Q10) of our newly developed questionnaire, in order to evaluate their comprehension by patients and their reproducibility in time. Study Design: The study is a systematic review regarding the evaluation of the existing questionnaire and a cohort study regarding the validation of our new MSGS questionnaire. Materials and Methods: A Multidisciplinary Salivary Gland Society (MSGS) questionnaire consisting of 20 questions and two scoring systems was developed to quantify symptoms of dry mouth and sialadenitis. Validation of the questionnaire was carried out on 199 patients with salivary pathologies (digestive, nasal, or age-related xerostomia, post radiation therapy, post radioiodine therapy, Sjögren's syndrome, IgG4 disease, recurrent juvenile parotitis, stones, and strictures) and a control group of 66 healthy volunteers. The coherence of the questionnaire's items, its reliability to distinguish patients from healthy volunteers, its comparison with unstimulated sialometry, and the time to fill both versions were assessed. Results: The novel MSGS questionnaire showed good internal coherence of the items, indicating its pertinence: the scale reliability coefficients amounted to a Cronbach's alpha of 0.92 for Q10 and 0.90 for Q3. The time to complete Q3 and Q10 amounted, respectively, to 5.23 min (±2.3 min) and 5.65 min (±2.64 min) for patients and to 3.94 min (±3.94 min) and 3.75 min (±2.11 min) for healthy volunteers. The difference between Q3 and Q10 was not significant. Conclusion: We present a novel self-administered questionnaire quantifying xerostomia and non-tumoral salivary gland pathologies. We recommend the use of the Q10 version, as its scale type is well known in the literatu

Published
2021

22. The RAI-6 questionnaire: a new screening questionnaire to monitor complications of radioiodine treatment

Author

Buchholzer, Samanta, Thakachy, Subha Sethu, Tchérémissinoff, Livia, Boselie, Franciscus, Triponez, Frédéric, Faure, Frédéric, Lopez, Jean Michel, Borner, Urs, Kleinjung, Tobias, Seebach, Jörg D., Dulguerov, Pavel, Marchal, Francis, Buchholzer, Samanta, Thakachy, Subha Sethu, Tchérémissinoff, Livia, Boselie, Franciscus, Triponez, Frédéric, Faure, Frédéric, Lopez, Jean Michel, Borner, Urs, Kleinjung, Tobias, Seebach, Jörg D., Dulguerov, Pavel, and Marchal, Francis

Abstract

Objective: The aim of this study is to develop a simple and efficient screening questionnaire to be able to routinely monitor potential radioiodine therapy-induced complications. Materials and Methods: A new radioiodine 6 (RAI-6) questionnaire containing six questions adressing salivary, ocular, and nasal symptoms as well as quality of life was developed. Validation of the RAI-6 questionnaire was assessed with a group of fifty-four patients diagnosed with differentiated thyroid carcinoma treated post-operatively with radioiodine therapy, and in a group of fifty healthy volunteers. The patient’s group was subdivided into subgroups according to the radioiodine dose received: 23 patients received less or 30 mCi, 28 patients received 100 mCi, and three patients received between 200 and 300 mCi. We asked the patients to complete the RAI-6 questionnaire in a retrospective manner, regarding their situation before radioiodine therapy and regarding their actual symptoms after radioiodine therapy. The time needed to complete the RAI-6 was also assessed both in patients and in healthy volunteers. Results: The mean post radioiodine treatment RAI-6 score were significantly higher than the mean pre radioiodine RAI-6 scores (p < 0.001) and the scores of healthy participants (p < 0.001). The mean total RAI-6 scores increased significantly with increasing radioiodine dose. A total mean RAI-6 score of each question was also analysed and revealed that ocular and nasal discomfort as well as quality of life were the items which affected the patients most after radioiodine treatment. The mean time to fill the RAI-6 questionnaire was 2 min for patients and 49 s for healthy volunteers. Conclusion: The RAI-6 represents a new questionnaire which is easy and quick to complete. This simple screening tool can be recommended for general clinical practise and further epidemiological research.

Published
2021

28. Salivary and lacrimal dysfunction after radioactive iodine for differentiated thyroid cancer: American Head and Neck Society Endocrine Surgery Section and Salivary Gland Section joint multidisciplinary clinical consensus statement of otolaryngology, ophthalmology, nuclear medicine and endocrinology

Author

Singer, Michael C., primary, Marchal, Francis, additional, Angelos, Peter, additional, Bernet, Vic, additional, Boucai, Laura, additional, Buchholzer, Samanta, additional, Burkey, Brian, additional, Eisele, David, additional, Erkul, Evren, additional, Faure, Frederic, additional, Freitag, Suzanne K., additional, Gillespie, Marion Boyd, additional, Harrell, Richard Mack, additional, Hartl, Dana, additional, Haymart, Megan, additional, Leffert, Jonathan, additional, Mandel, Susan, additional, Miller, Barbra S., additional, Morris, John, additional, Pearce, Elizabeth N., additional, Rahmati, Rahmatullah, additional, Ryan, William R., additional, Schaitkin, Barry, additional, Schlumberger, Martin, additional, Stack, Brendan C., additional, Van Nostrand, Doug, additional, Wong, Ka Kit, additional, and Randolph, Gregory, additional

Published
2020
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34. Nouveautés en médecine 2018: ORL

Author

Marchal, Francis and Senn, Pascal

Subjects
Otolaryngology/trends, Humans, Child, Otorhinolaryngologic Diseases/therapy, ddc:616.8, Aged
Abstract

Les actualités thérapeutiques en ORL 2018, établies à partir de plus de 15 000 abstracts, se veulent une fois de plus généralistes. En ORL générale, les sujets seront le miel, les apnées du sommeil, l'adénotonsillectomie et l'immunothérapie. En otologie, l'otite moyenne aiguë et la mastoïdite, les nouvelles technologies, l'implant cochléaire chez le patient âgé, la surdité et l'intérêt des cultures de cellules ciliées. En rhinologie, la rhinosinusite et ses traitements dont le xylitol, l'apport de nouvelles technologies et l'épistaxis. En laryngologie et chirurgie thyroïdienne, les guidelines pour la dysphonie, l'intérêt de l'ultrason en préopératoire et les résultats en chirurgie thyroïdienne selon la formation. En chirurgie cervico-faciale, le VPH, l'immunothérapie, l'intérêt du cannabis et la possibilité de diagnostics tumoraux précoces dans la salive. En glandes salivaires, la sialendoscopie, la transposition de canaux salivaires et la détection de maladies à l'aide de biomarqueurs dans la salive

Published
2019

42. Do Postoperative Oral Corticosteroids Improve Results After Sialendoscopy for Ductal Stenosis?

Author

Paiva Leite, Sandro Henrique, Morton, Randall P., Ahmad, Zahoor, and Marchal, Francis

Abstract

Objectives: This study aims to review the effects of short‐ and long‐term oral administration of postoperative corticosteroids in patients undergoing sialendoscopy for the treatment of obstructive sialadenitis due to ductal stenosis. Study Design: Prospective comparative study. Methods: A prospective observational study was conducted at Manukau Surgical Center in Auckland, New Zealand, where patients undergoing sialendoscopic surgery for recurrent obstructive sialadenitis due to ductal stenoses were reviewed. Univariable and multivariable analysis, and also logistic regression were performed to identify variables correlated with the likelihood of the need for revision surgery for persistent or recurrent symptoms. Results: In this study, sialendoscopy was performed in 142 patients: 162 parotid glands (86.6%) and 25 submandibular glands (13.4%). Postoperative oral steroids were prescribed for 48 patients (34%); 19 (13%) were prescribed for less than 7 days and 29 (20%) for more than 7 days. In total, 33 patients (23.2%) required a revision sialendoscopy during follow‐up due to recurrence of symptoms. Oral steroids prescribed for more than 7 days after a sialendoscopy reduced the likelihood of a revision procedure by 93% when compared with patients who did not receive this medication, and by 96% when compared with patients who received steroids for less than 7 days. Conclusion: The results showed that in our population oral administration of corticosteroids for more than 7 days after sialendoscopy for the treatment of recurrent obstructive sialadenitis due to ductal stenosis markedly reduced the need for later revision surgery. Routine use of corticosteroids for more than 7 days is recommended after sialendoscopy in patients with ductal stenosis. Level of Evidence: II Laryngoscope, 131:E1503–E1509, 2021 [ABSTRACT FROM AUTHOR]

Published
2021
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43. Comparison of Clinical Characteristics and Magnetic Resonance Imaging of Salivary Glands With Magnetic Resonance Sialography in Sjögren's Syndrome.

Author

André, Raphaël, Becker, Minerva, Lombardi, Tommaso, Buchholzer, Samanta, Marchal, Francis, and Seebach, Jorg D.

Abstract

Objectives/hypothesis: To compare the results of magnetic resonance imaging with magnetic resonance sialography (MRSIAL) and the clinical and laboratory characteristics in a well-characterized cohort of patients with primary or secondary Sjögren's syndrome (SS) meeting the American-European Consensus Group criteria.Study Design: Retrospective, observational, monocentric study.Methods: Thirty-six patients (81% female, mean age = 48 ± 35 years) with primary or secondary SS who underwent MRSIAL were included in the study.Results: MRSIAL revealed characteristic radiological signs in the parotid, sublingual, and submandibular salivary glands in 35/36 patients (97%). Patients presenting with anti-Sjögren's syndrome-related antigen A (SSA) autoantibodies showed more often fatty infiltration, a "pepper-and-salt" appearance, ductal stenosis, and/or ductal dilation of the parotid gland (88%, 88%, and 72% respectively) than patients negative for anti-SSA (12%, 4%, and 28% respectively). MRSIAL demonstrated signs characteristic of SS in all 11 patients with negative minor salivary gland biopsy. For 15 patients undergoing ultrasound examination only, 11 (73%) had SS findings, but all 15 had SS findings on MRSIAL. Two cases of parotid lymphoma were detected by MRSIAL (6%).Conclusions: MRSIAL is a reliable technique to detect glandular anomalies in patients with SS, and seems to provide a valuable aid in the diagnosis of SS.Level Of Evidence: 4 Laryngoscope, 131:E83-E89, 2021. [ABSTRACT FROM AUTHOR]

Published
2021
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46. Virus Burden in Lymph Nodes and Blood of Subjects with Primary Human Immunodeficiency Virus Type 1 Infection on Bitherapy

Author

Perrin, Luc, Yerly, Sabine, Marchal, Francis, Schockmel, Gérard A., Hirschel, Bernard, Fox, Cecil H., Pantaleo, Giuseppe, Perrin, Luc, Yerly, Sabine, Marchal, Francis, Schockmel, Gérard A., Hirschel, Bernard, Fox, Cecil H., and Pantaleo, Giuseppe

Abstract

At present, it is not known whether undetectable plasma viremia corresponds to an absence of human immunodeficiency virus type 1 (HIV-1) replication in lymphoid tissues. This issue has been explored in 11 subjects with primary HIV-1 infection treated with zidovudine plus didanosine by evaluating virologic markers in blood and lymphoid tissues 9-18 months after initiation of treatment. These markers include plasma viremia, measured with a sensitive assay with a detection limit of 20 HIV-1 RNA copies/mL, infectious virus titers and proviral DNA in lymph node mononuclear cells, and HIV-1 RNA in lymphoid tissue. Five subjects had plasma viremia < 20 copies/mL and showed no evidence of viral replication in lymphoid tissue. Six subjects had both detectable plasma viremia and evidence of HIV-1 RNA in lymphoid tissue. The results indicate that absence of detectable HIV RNA in lymphoid tissue is associated with viremia levels of HIV-1 RNA < 20 copies/mL

Published
2017

50. Sialendoscopy: what is it and what is its awareness?

Author

MS Hoofd-Hals Chirurgische Oncologie, Prasad, Shashi, Pezier, Thomas, Faure, Frederic, Marchal, Francis, MS Hoofd-Hals Chirurgische Oncologie, Prasad, Shashi, Pezier, Thomas, Faure, Frederic, and Marchal, Francis

Published
2016

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