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1. Early phylodynamics analysis of the COVID-19 epidemic in France

Author

Danesh, Gonché, Elie, Baptiste, Michalakis, Yannis, Sofonea, Mircea T, Bal, Antonin, Behillil, Sylvie, Destras, Grégory, Boutolleau, David, Burrel, Sonia, Marcelin, Anne-Geneviève, Plantier, Jean-Christophe, Thibault, Vincent, Simon-Loriere, Etienne, van der Werf, Sylvie, Lina, Bruno, Josset, Laurence, Enouf, Vincent, and Alizon, Samuel

Subjects
Archaeology, CC1-960, Science
Abstract

France was one of the first countries to be reached by the COVID-19 pandemic. Here, we analyse 196 SARS-Cov-2 genomes collected between Jan 24 and Mar 24 2020, and perform a phylodynamics analysis. In particular, we analyse the doubling time, reproduction number (ℛt) and infection duration associated with the epidemic wave that was detected in incidence data starting from Feb 27. Different models suggest a slowing down of the epidemic in Mar, which would be consistent with the implementation of the national lock-down on Mar 17. The inferred distributions for the effective infection duration and ℛt are in line with those estimated from contact tracing data. Finally, based on the available sequence data, we estimate that the French epidemic wave originated between mid-Jan and early Feb. Overall, this analysis shows the potential to use sequence genomic data to inform public health decisions in an epidemic crisis context and calls for further analyses with denser sampling.

Published
2021
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2. SARS-CoV-2 genomic surveillance and reliability of PCR single point mutation assay (SNPsig® SARS-CoV-2 EscapePLEX CE) for the rapid detection of variants of concern in Cameroon

Author

Fokam, Joseph, Gouissi Anguechia, Davy-Hyacinthe, Takou, Desire, Jagni Semengue, Ezechiel Ngoufack, Chenwi, Collins, Beloumou, Grace, Djupsa, Sandrine, Nka, Alex Durand, Togna Pabo, Willy Le Roi, Abba, Aissatou, Ka'e, Aude Christelle, Kengni, Aurelie, Etame, Naomi Karell, Moko, Larissa Gaelle, Molimbou, Evariste, Nayang Mundo, Rachel Audrey, Tommo, Michel, Fainguem, Nadine, Fotsing, Lionele Mba, Colagrossi, Luna, Alteri, Claudia, Ngono, Dorine, Otshudiema, John Otokoye, Ndongmo, Clement, Boum, Yap, Etoundi, Georges Mballa, Halle, Edie G.E., Eben-Moussi, Emmanuel, Montesano, Carla, Marcelin, Anne-Genevieve, Colizzi, Vittorio, Perno, Carlo-Federico, Ndjolo, Alexis, and Ndembi, Nicaise

Published
2024
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4. Novel scores relevant to antimicrobial resistance and hospital-acquired infections developed with data from a multi-hospital consortium in the Parisian region of France

Author

Lefevre, Laurence Armand, Aubry, Alexandra, Avettand-Fenoel, Véronique, Barbut, Frédéric, Belec, Laurent, Bercot, Béatrice, Bonacorsi, Stéphane, Calvez, Vincent, Cambau, Emmanuelle, Carbonnelle, Etienne, Charpentier, Charlotte, Chevaliez, Stéphane, Decousser, Jean-Winoc, Delaugerre, Constance, Descamps, Diane, Dortet, Laurent, Doucet-Populaire, Florence, Frange, Pierre, Fourati, Slim, Gaillard, Jean-Louis, Gault, Elyanne, Herrmann, Jean-Louis, Jarlier, Vincent, Kerneis, Solen, Le Goff, Jérôme, Mainardi, Jean-Luc, Marcelin, Anne-Geneviève, Morand-Joubert, Laurence, Pawlotsky, Jean-Michel, Poyart, Claire, Rameix-Welti, Marie-Anne, Robert, Jérôme, Rodriguez, Christophe, Roque Afonso, Anne-Marie, Rottman, Martin, Rozenberg, Flore, Ruppé, Etienne, Skurnik, David, Veziris, Nicolas, Zahar, Jean-Ralph, Barnaud, Guilene, Billard-Pomares, Typhaine, Cuzon, Gaëlle, Decré, Dominique, Doloy, Alexandra, Donay, Jean-Luc, Drieux-Rouzet, Laurence, Durand, Isabelle, Ferroni, Agnès, Fihman, Vincent, Fortineau, Nicolas, Gomart, Camille, Grall, Nathalie, Guillet-Caruba, Christelle, Jaureguy, Françoise, Lalande, Valérie, Landraud, Luce, Leflon, Véronique, Mariani, Patricia, Mihaila, Liliana, Moissenet, Didier, Noussair, Latifa, Podglajen, Isabelle, Poilane, Isabelle, Poupet, Hélène, Rondinaud, Emilie, Tardy, Valérie Sivadon, Trystram, David, Verdet, Charlotte, Vigier, Emmanuelle, Vimont-Billarant, Sophie, Amarsy, R., Granger, B., Fournier, S., Monteil, C., Trystram, D., Siorat, V., Jarlier, V., and Robert, J.

Published
2024
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5. Viral loads in clinical samples of men with monkeypox virus infection: a French case series

Author

Palich, Romain, Burrel, Sonia, Monsel, Gentiane, Nouchi, Agathe, Bleibtreu, Alexandre, Seang, Sophie, Bérot, Vincent, Brin, Cécile, Gavaud, Ariane, Wakim, Yara, Godefroy, Nagisa, Fayçal, Antoine, Tamzali, Yanis, Grunemwald, Thomas, Ohayon, Michel, Todesco, Eve, Leducq, Valentin, Marot, Stéphane, Calvez, Vincent, Marcelin, Anne-Geneviève, and Pourcher, Valérie

Published
2023
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6. The RT M184V resistance mutation clearance in the reservoir is mainly related to CD4 nadir and viral load zenith independently of therapeutic regimen type

Author

Teyssou, Elisa, primary, Soulie, Cathia, additional, Fauchois, Antoine, additional, Palich, Romain, additional, Nouchi, Agathe, additional, Sayon, Sophie, additional, Abdi, Basma, additional, Wirden, Marc, additional, Katlama, Christine, additional, Pourcher, Valérie, additional, Marcelin, Anne-Geneviève, additional, and Calvez, Vincent, additional

Published
2024
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7. Ultra-rapid selection of the N74D capsid inhibitor resistance mutation after 3 weeks on lenacapavir

Author

Wirden, Marc, primary, Pouderoux, Cecile, additional, Peytavin, Gilles, additional, Abdi, Basma, additional, Fayçal, Antoine, additional, Palich, Romain, additional, Valantin, Marc Antoine, additional, Seang, Sophie, additional, Katlama, Christine, additional, Calvez, Vincent, additional, Pourcher, Valerie, additional, and Marcelin, Anne-Geneviève, additional

Published
2024
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8. Anti-SARS-CoV-2 glyco-humanized polyclonal antibody XAV-19: phase II/III randomized placebo-controlled trial shows acceleration to recovery for mild to moderate patients with COVID-19

Author

Poulakou, Garyfallia, primary, Royer, Pierre-Joseph, additional, Evgeniev, Nikolay, additional, Evanno, Gwénaëlle, additional, Shneiker, Françoise, additional, Marcelin, Anne-Geneviève, additional, Vanhove, Bernard, additional, Duvaux, Odile, additional, Marot, Stéphane, additional, and Calvez, Vincent, additional

Published
2024
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9. Virological efficacy of switch to DTG plus 3TC in a retrospective observational cohort of suppressed HIV-1 patients with or without past M184V: the LAMRES study

Author

Santoro, Maria Mercedes, Armenia, Daniele, Teyssou, Elisa, Santos, José Ramón, Charpentier, Charlotte, Lambert-Niclot, Sidonie, Antinori, Andrea, Katlama, Christine, Descamps, Diane, Perno, Carlo Federico, Calvez, Vincent, Paredes, Roger, Ceccherini-Silberstein, Francesca, and Marcelin, Anne Geneviève

Published
2022
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12. Phenotypic Heterogeneity of Fulminant COVID-19--Related Myocarditis in Adults

Author

Barhoum, Petra, Pineton de Chambrun, Marc, Dorgham, Karim, Kerneis, Mathieu, Burrel, Sonia, Quentric, Paul, Parizot, Christophe, Chommeloux, Juliette, Bréchot, Nicolas, Moyon, Quentin, Lebreton, Guillaume, Boussouar, Samia, Schmidt, Matthieu, Yssel, Hans, Lefevre, Lucie, Miyara, Makoto, Charuel, Jean-Luc, Marot, Stéphane, Marcelin, Anne-Geneviève, Luyt, Charles-Edouard, Leprince, Pascal, Amoura, Zahir, Montalescot, Gilles, Redheuil, Alban, Combes, Alain, Gorochov, Guy, and Hékimian, Guillaume

Published
2022
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13. Cumulative incidence of SARS-CoV-2 infection and associated risk factors among frontline health care workers in Paris: the SEROCOV cohort study

Author

Hausfater, Pierre, Boutolleau, David, Lacombe, Karine, Beurton, Alexandra, Dumont, Margaux, Constantin, Jean-Michel, Ghosn, Jade, Combes, Alain, Cury, Nicolas, Guedj, Romain, Djibré, Michel, Bompard, Rudy, Mazerand, Sandie, Pourcher, Valérie, Gimeno, Linda, Marois, Clémence, Teyssou, Elisa, Marcelin, Anne-Geneviève, Hajage, David, and Tubach, Florence

Published
2022
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15. Similar Viral and Immune Characteristics of Kaposi Sarcoma in ART-treated People Living With HIV and Older Patients With Classic Kaposi Sarcoma.

Author

Royston, Léna, Jary, Aude, Berini, Carolina A, Mabanga, Tsoarello, Lin, John, Pagliuzza, Amélie, Chomont, Nicolas, Litvinov, Ivan V, Calmy, Alexandra, Leducq, Valentin, Calvez, Vincent, Marcelin, Anne-Geneviève, Isnard, Stéphane, and Routy, Jean-Pierre

Subjects
MONONUCLEAR leukocytes, GRANULOCYTE-colony stimulating factor, PLATELET-derived growth factor, HIV, KAPOSI'S sarcoma
Abstract

Background Reemergence of human herpesvirus 8 (HHV-8)–induced Kaposi sarcoma (KS) in people living with HIV (PLWH) despite antiretroviral therapy (ART) poses a clinical challenge because they already have favorable CD4 T-cell numbers and undetectable viral loads. We observed that clinical presentation in PLWH on ART resembled classic KS found in older HIV-uninfected patients and hypothesized that immunosenescence may thus play a role in occurrence of KS on ART. We compared viral and immune factors implicated in the development of KS in ART-treated PLWH (HIV KS) and HIV-uninfected classic KS patients (cKS), compared to controls without KS (HIV Control, cControls respectively). Methods Plasma, peripheral blood mononuclear cell, and skin tissues were obtained from 11 HIV KS and 11 cKS patients and 2 groups of age-matched controls. Results HIV KS participants were younger than cKS (aged 53 vs 75 years). HHV-8 genotypes did not differ between groups. Despite the younger age and a lower CD4/CD8 ratio, activated, exhausted, and senescent T-cell frequencies were similar between HIV KS and cKS. Anti–HHV-8 immunoglobulin G levels were higher and circulating HHV-8 DNA lower in HIV KS compared with cKS. Circulating platelet-derived growth factors AA-BB and granulocyte colony-stimulating factors were higher in HIV KS We observed similar levels of HHV-8 DNA and PD-1 expression in skin lesions from HIV KS and cKS patients. Conclusions Altogether, early immune senescence could be involved in the development of KS in ART-treated PLWH. Higher anti–HHV-8 immunoglobulin G levels could be linked with lower circulating viral load. Such insights should help developing therapeutical strategies to prevent development and treat KS in PLWH on ART. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Performance of 30 commercial SARS-CoV-2 serology assays in testing symptomatic COVID-19 patients

Author

Vauloup-Fellous, Christelle, Maylin, Sarah, Périllaud-Dubois, Claire, Brichler, Ségolène, Alloui, Chakib, Gordien, Emmanuel, Rameix-Welti, Marie-Anne, Gault, Elyanne, Moreau, Frédérique, Fourati, Slim, Challine, Dominique, Pawlotsky, Jean-Michel, Houhou-Fidouh, Nadhira, Damond, Florence, Mackiewicz, Vincent, Charpentier, Charlotte, Méritet, Jean-François, Rozenberg, Flore, Podglajen, Isabelle, Marot, Stéphane, Petit, Heloïse, Burrel, Sonia, Akhavan, Sepideh, Leruez-Ville, Marianne, Avettand-Fenoel, Véronique, Fourgeaud, Jacques, Guilleminot, Tiffany, Gardiennet, Elise, Bonacorsi, Stéphane, Carol, Agnès, Carcelain, Guislaine, Villemonteix, Juliette, Boukli, Narjis, Gozlan, Joël, Morand-Joubert, Laurence, Legoff, Jérome, Delaugerre, Constance, Chaix, Marie-Laure, Roque-Afonso, Ana-Maria, Dortet, Laurent, Naas, Thierry, Ronat, Jean-Baptiste, Lepape, Samuel, Marcelin, Anne-Geneviève, and Descamps, Diane

Published
2021
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17. Impact of Human Immunodeficiency Virus Type 1 Minority Variants on the Virus Response to a Rilpivirine-Based First-line Regimen

Author

Raymond, Stéphanie, Nicot, Florence, Pallier, Coralie, Bellecave, Pantxika, Maillard, Anne, Trabaud, Mary Anne, Morand-Joubert, Laurence, Rodallec, Audrey, Amiel, Corinne, Mourez, Thomas, Bocket, Laurence, Beby-Defaux, Agnès, Bouvier-Alias, Magali, Lambert-Niclot, Sidonie, Charpentier, Charlotte, Malve, Brice, Mirand, Audrey, Dina, Julia, Le Guillou-Guillemette, Hélène, Marque-Juillet, Stéphanie, Signori-Schmuck, Anne, Barin, Francis, Si-Mohamed, Ali, Fenoel, Véronique Avettand, Roussel, Catherine, Calvez, Vincent, Saune, Karine, Marcelin, Anne Geneviève, Rodriguez, Christophe, Descamps, Diane, Izopet, Jacques, Lagier, E, Roussel, C, Le Guillou-Guillemette, H, Alloui, C, Bettinger, D, Pallier, C, Fleury, H, Reigadas, S, Bellecave, P, Recordon-Pinson, P, Payan, C, Vallet, S, Vabret, A, Dina, J, Henquell, C, Mirand, A, Bouvier-Alias, M, de Rougemont, A, Dos Santos, G, Morand, P, Signori-Schmuck, A, Bocket, L, Rogez, S, Andre, P, Tardy, JC, Trabaud, MA, Tamalet, C, Delamare, C, Montes, B, Schvoerer, E, Ferré, V, André-Garnier, E, Cottalorda, J, Guinard, J, Guiguon, A, Descamps, D, Brun-Vézinet, F, Charpentier, C, Visseaux, B, Peytavin, G, Krivine, A, Si-Mohamed, A, Avettand-Fenoel, V, Marcelin, AG, Calvez, V, Lambert-Niclot, S, Soulié, C, Wirden, M, Morand-Joubert, L, Delaugerre, C, Chaix, ML, Amiel, C, Schneider, V, Giraudeau, G, Defaux, A Beby-, Brodard, V, Maillard, A, Plantier, JC, Chaplain, C, Bourlet, T, Fafi-Kremer, S, Stoll-Keller, F, Schmitt, MP, Barth, H, Yerly, S, Poggi, C, Izopet, J, Raymond, S, and Barin, F

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, Immunology, Antimicrobial Resistance, Genetics, HIV/AIDS, Clinical Research, Infectious Diseases, Aetiology, 2.1 Biological and endogenous factors, Infection, Good Health and Well Being, Adult, Drug Resistance, Viral, Female, Genetic Variation, HIV Infections, HIV-1, Humans, Male, Mutation, Rilpivirine, Viral Load, minority resistant variants, rilpivirine, first-line antiretroviral therapy, ultra-deep sequencing, French National Agency for Research on AIDS and Viral Hepatitis (ANRS) AC11 Resistance Study Group, Biological Sciences, Medical and Health Sciences, Microbiology, Clinical sciences
Abstract

BackgroundMinority resistant variants of human immunodeficiency virus type 1 (HIV-1) could influence the virological response to treatment based on nonnucleoside reverse transcriptase inhibitors (NNRTIs). Data on minority rilpivirine-resistant variants are scarce. This study used next-generation sequencing (NGS) to identify patients harboring minority resistant variants to nucleos(t)ide reverse transcriptase inhibitors and NNRTIs and to assess their influence on the virological response (VR).MethodsAll the subjects, 541 HIV-1-infected patients started a first-line regimen containing rilpivirine. VR was defined as a HIV-1 RNA load 20% in 29% of samples. We identified 43 (8.8%) and 36 (7.4%) patients who harbored rilpivirine-resistant variants with a 1% sensitivity threshold according to the French National Agency for Research on AIDS and Viral Hepatitis and Stanford algorithms, respectively. The VR was 96.9% at month 12. Detection of minority rilpivirine resistant variants was not associated with virological failure (VF). Multivariate analysis indicated that VF at month 12 was associated with a CD4 count

Published
2018

18. Low unspliced cell-associated HIV RNA in early treated adolescents living with HIV on long suppressive ART

Author

Gärtner, Kathleen, primary, Domínguez-Rodríguez, Sara, additional, Heaney, Judith, additional, Gkouleli, Triantafylia, additional, Grant, Paul, additional, Dorgham, Karim, additional, Sauce, Delphine, additional, Soulie, Cathia, additional, Busby, Eloise J., additional, O’Sullivan, Denise M., additional, Spyer, Moira, additional, Botha, Johannes C., additional, Muñoz-Fernandez, Maria Angeles, additional, Tagarro, Alfredo, additional, Cotugno, Nicola, additional, Huggett, Jim F., additional, Klein, Nigel, additional, Palma, Paolo, additional, Rojo Conejo, Pablo, additional, Foster, Caroline, additional, Giaquinto, Carlo, additional, Rossi, Paolo, additional, Persaud, Deborah, additional, De Rossi, Anita, additional, Marcelin, Anne-Geneviève, additional, and Nastouli, Eleni, additional

Published
2024
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19. Use of genotypic HIV DNA testing: a DELPHI-type consensus

Author

Andre-Garnier, Elisabeth, primary, Bocket, Laurence, additional, Bourlet, Thomas, additional, Hocqueloux, Laurent, additional, Lepiller, Quentin, additional, Maillard, Anne, additional, Reigadas, Sandrine, additional, Barriere, Guillaume, additional, Durand, François, additional, Montes, Brigitte, additional, Stefic, Karl, additional, and Marcelin, Anne-Geneviève, additional

Published
2024
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20. Seroprevalence of Crimean-Congo hemorrhagic fever virus among people living with HIV in Brazzaville, Congo and among blood donors in Bamako, Mali

Author

Malonga, Gervillien Arnold, primary, Maiga, Almoustapha Issiaka, additional, Moudiongui Mboungou Malanda, Dimitry, additional, Saliou, Mahamadou, additional, Malanda-Kiminou, Juthèce Private, additional, Dolo, Oumar, additional, Boumba, Anicet Luc Magloire, additional, Ba, Alhassane, additional, Murphy, Robert, additional, Peko, Jean Félix, additional, Marcelin, Anne-Geneviève, additional, Calvez, Vincent, additional, and Marot, Stéphane, additional

Published
2024
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21. Prevalence of cervical HPV infection, sexually transmitted infections and associated antimicrobial resistance in women attending cervical cancer screening in Mali

Author

Jary, Aude, Teguete, Ibrahima, Sidibé, Younoussa, Kodio, Amadou, Dolo, Oumar, Burrel, Sonia, Boutolleau, David, Beauvais-Remigereau, Laurianne, Sayon, Sophie, Kampo, Mamadou, Traoré, Fatoumata Tata, Sylla, Mariam, Achenbach, Chad, Murphy, Robert, Berçot, Béatrice, Bébéar, Cécile, Calvez, Vincent, Marcelin, Anne-Geneviève, and Maiga, Almoustapha I.

Published
2021
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22. SARS-CoV-2 infection in patients with primary central nervous system lymphoma

Author

Laurenge, Alice, Ursu, Renata, Houillier, Caroline, Abdi, Basma, Tebano, Gianpiero, Quemeneur, Cyril, Choquet, Sylvain, Di Blasi, Roberta, Lozano, Fernando, Morales, Andrea, Durán-Peña, Alberto, Sirven-Villaros, Lila, Mathon, Bertrand, Mokhtari, Karima, Bielle, Franck, Martin-Duverneuil, Nadine, Delattre, Jean-Yves, Marcelin, Anne-Geneviève, Pourcher, Valérie, Alentorn, Agusti, Idbaih, Ahmed, Carpentier, Antoine F., Leblond, Véronique, Hoang-Xuan, Khê, and Touat, Mehdi

Published
2021
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25. Spike Protein Genetic Evolution in Patients at High Risk of Severe Coronavirus Disease 2019 Treated by Monoclonal Antibodies.

Author

Leducq, Valentin, Zafilaza, Karen, Fauchois, Antoine, Ghidaoui, Emna, Sayon, Sophie, Dorival, Céline, Meledje, Marie-Laure, Lusivika-Nzinga, Clovis, Yordanov, Youri, Martin-Blondel, Guillaume, Carrat, Fabrice, Marcelin, Anne-Geneviève, and Soulie, Cathia

Subjects
SARS-CoV-2, COVID-19, MONOCLONAL antibodies, CORONAVIRUS diseases
Abstract

Background High-risk patients, often immunocompromised and not responding to vaccine, continue to experience severe coronavirus disease 2019 (COVID-19) and death. Monoclonal antibodies (mAbs) were shown to be effective to prevent severe COVID-19 for these patients. Nevertheless, concerns about the emergence of resistance mutations were raised. Methods We conducted a multicentric prospective cohort study, including 264 patients with mild to moderate COVID-19 at high risk for progression to severe COVID-19 and treated early with casirivimab/imdevimab, sotrovimab, or tixagevimab/cilgavimab. We sequenced the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome during follow-up and searched for emerging spike mutations. Results Immunocompromised patients have a 6-fold increased risk of developing mutations, which are associated with a prolonged duration of viral clearance but no clinical worsening. Emerging P337S/R/L/H, E340D/K/A/Q/V/G, and K356T/R substitutions in patients treated with sotrovimab are associated with higher viral RNA loads for up to 14 days post–treatment initiation. Tixagevimab/cilgavimab is associated with a 5-fold increased risk of developing mutations. R346K/I/T/S and K444R/N/M substitutions associated with tixagevimab/cilgavimab have been identified in multiple SARS-CoV-2 lineages, including BQ.1 and XBB. Conclusions The probability of emerging mutations arising in response to mAbs is significant, emphasizing the crucial need to investigate these mutations thoroughly and assess their impact on patients and the evolutionary trajectory of SARS-CoV-2. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Higher levels of SARS-CoV-2 genetic variation in immunocompromised patients: a retrospective case-control study

Author

Guilbaud, Romane, primary, Franco Yusti, Anna-Maria, additional, Leducq, Valentin, additional, Zafilaza, Karen, additional, Bridier-Nahmias, Antoine, additional, Todesco, Eve, additional, Soulie, Cathia, additional, Fauchois, Antoine, additional, Le Hingrat, Quentin, additional, Kramer, Laura, additional, Goulenok, Tiphaine, additional, Salpin, Mathilde, additional, Daugas, Eric, additional, Dorent, Richard, additional, Ottaviani, Sébastien, additional, Zalcman, Gérard, additional, Ghosn, Jade, additional, Choquet, Sylvain, additional, Cacoub, Patrice, additional, Amoura, Zahir, additional, Barroux, Benoit, additional, Pourcher, Valérie, additional, Spano, Jean-Philippe, additional, Louet, Martine, additional, Marcelin, Anne-Geneviève, additional, Calvez, Vincent, additional, Charpentier, Charlotte, additional, Descamps, Diane, additional, Marot, Stéphane, additional, Ferré, Valentine Marie, additional, and Coppée, Romain, additional

Published
2023
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28. Comparative Performance of Anyplex II HPV28 and Cobas 4800 Human Papillomavirus (HPV) Assays for High-Risk HPV Detection in Self-collected Anal Samples

Author

Delvallez, Gauthier, primary, Cheng, Sokleaph, additional, Marot, Stéphane, additional, Malonga, Gervillien Arnold, additional, Cocherie, Théophile, additional, Wignall, Steve, additional, Calvez, Vincent, additional, Phal, Sophat, additional, Vichet, Kem, additional, Marcelin, Anne-Geneviève, additional, and Jary, Aude, additional

Published
2023
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29. Sotrovimab therapy elicits antiviral activities against Omicron BQ.1.1 and XBB.1.5 in sera of immunocompromised patients

Author

Bruel, Timothée, primary, Vrignaud, Lou-Léna, additional, Porrot, Françoise, additional, Staropoli, Isabelle, additional, Planas, Delphine, additional, Guivel-Benhassine, Florence, additional, Puech, Julien, additional, Prot, Matthieu, additional, Munier, Sandie, additional, Bolland, William Henry, additional, Soulié, Cathia, additional, Zafilaza, Karen, additional, Lusivika-Nzinga, Clovis, additional, Meledge, Marie-Laure, additional, Dorival, Céline, additional, Molino, Diana, additional, Péré, Hélène, additional, Yordanov, Youri, additional, Simon-Lorière, Etienne, additional, Veyer, David, additional, Carrat, Fabrice, additional, Schwartz, Olivier, additional, Marcelin, Anne-Geneviève, additional, Martin-Blondel, Guillaume, additional, Garcia, Magalie, additional, Giraud, Valentin, additional, Metais, Agathe, additional, Cazenave-Roblot, Fance, additional, Martellosio Anne-Marie Ronchetti, Jean-Philippe, additional, Gabas, Thomas, additional, Hadjadj, Naima, additional, Salanoubat, Célia, additional, Chabrol, Amélie, additional, Housset, Pierre, additional, Pardon, Agathe, additional, Faucon, Anne-Laure, additional, Caudwell, Valérie, additional, Roland Liblau, Latifa Hanafi, additional, Alric, Laurent, additional, Pugnet, Grégory, additional, Mourguet, Morgane, additional, Bories, Eva, additional, Bonnet, Delphine, additional, Charpentier, Sandrine, additional, Delobel, Pierre, additional, Debard, Alexa, additional, Beck, Colleen, additional, Boumaza, Xavier, additional, Fanny Lanternier, Stella Rousset, additional, Delage, Claire, additional, Pires, Elisabete Gomes, additional, Cheminant, Morgane, additional, Anthony Chauvin, Nathalie Chavarot, additional, Véronique Delcey Simon Bessis, Xavier Eyer, additional, Cresta, Mélanie, additional, Pélagie Thibaut, Romain Gueneau, additional, Nadal, Marine, additional, Siguier, Martin, additional, Bachir, Marwa, additional, Valérie Pourcher, Christia Palacios, additional, Melenotte, Cléa, additional, Faycal, Antoine, additional, Berot, Vincent, additional, Brin, Cécile, additional, Djebara, Siham, additional, Marot, Stéphane, additional, Sayon, Sophie, additional, Leducq, Vincent, additional, Malet, Isabelle, additional, Teyssou, Elisa, additional, Karine Lacombe, Adélie Gothland, additional, Aad, Yasmine Abi, additional, Chiarabini, Thibault, additional, Feliho, Raynald, additional, Valin, Nadia, additional, Brigant, Fabien, additional, Boize, Julien, additional, Thiébaud, Pierre-Clément, additional, Moreau, Marie, additional, Nathalie De Castro, Charlotte Billard, additional, Liégeon, Geoffroy, additional, Denis, Blandine, additional, Molina, Jean-Michel, additional, André Cabié, Lucia Etheve, additional, Abel, Sylvie, additional, Cabras, Ornella, additional, Guitteaud, Karine, additional, François Vincent Dubee, Sandrine Pierre-, additional, Ndiaye, Diama, additional, Pehlivan, Jonathan, additional, Phelippeau, Michael, additional, Alexandre Duvignaud, Rafael Mahieu, additional, Pistone, Thierry, additional, Desclaux, Arnaud, additional, Neau, Didier, additional, Jean-François Faucher, Charles Cazanave, additional, Festou, Benjamin, additional, Dupuy-Grasset, Magali, additional, Loustaud-Ratti, Véronique, additional, Nathan Peiffer- Smadja, Delphine Chainier, additional, Choquet, Christophe, additional, Da Conceicao, Olivia, additional, Thy, Michael, additional, Collas, Lio, additional, Godard, Cindy, additional, Bouzid, Donia, additional, Ing, Vittiaroat, additional, Pereira, Laurent, additional, Pavlowsky, Thomas, additional, RavautAntoine Asquier-Khati, Camille, additional, Boutoille, David, additional, Chauveau, Marie, additional, Deschanvres, Colin, additional, Audrey Le Bot, François Raffi, additional, Cailleaux, Marine, additional, Benezit, François, additional, Maillard, Anne, additional, Hue, Benoit, additional, François Coustilleres, Pierre Tattevin, additional, Carvalho-Schneider, Claudia, additional, Jamard, Simon, additional, Petit, Laeticia, additional, Natacha Mrozek, Karl Stefic, additional, Theis, Clément, additional, Vidal, Magali, additional, Sauvat, Léo, additional, Benjamin Lefèvre, Delphine Martineau, additional, Baronnet, Guillaume, additional, Florence Ader, Agnès Didier, additional, Perpoint, Thomas, additional, Conrad, Anne, additional, Chabert, Paul, additional, Aurélie Martin, Pierre Chauvelot, additional, Loubet, Paul, additional, Mazet, Julien, additional, Larcher, Romaric, additional, Mathilde Devaux Jérôme Frey, Didier Laureillard, additional, Woerlen, Amos, additional, Remillon, Aline, additional, Absensur-Vuillaume, Laure, additional, Albert Trinh-Duc, Pauline Bouquet, additional, Philippe Petua, Patrick Rispal, additional, Aurore Perrot, Julien Carillo, additional, Delavigne, Karen, additional, Cougoul, Pierre, additional, Dion, Jérémie, additional, Mathieu Blot, Odile Rauzy, additional, Sixt, Thibault, additional, Moretto, Florian, additional, Charles, Carole, additional, Sophie Circosta, Lionel Piroth, additional, Leger, Lydia, additional, Arulananthan, Arulvani, additional, Lascoux, Carine, additional, Valérie, Pascaline, additional, Yazdan Yazdanpanah, Leia Becam, additional, Petrov-Sanchez, Ventzislava, additional, Diallo, Alpha, additional, Le Mestre, Soizic, additional, Le Meut Isabelle Goderel, Guillaume, additional, Chau, Frédéric, additional, Soltana, Brahim, additional, Chane Tang, Jessica, additional, Guedj, Jérémie, additional, and Caille, Yvanie, additional

Published
2023
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32. Antiretroviral-naive and -treated HIV-1 patients can harbour more resistant viruses in CSF than in plasma.

Author

Soulie, Cathia, Descamps, Diane, Grudé, Maxime, Schneider, Véronique, Trabaud, Mary-Anne, Morand-Joubert, Laurence, Delaugerre, Constance, Montes, Brigitte, Barin, Francis, Ferre, Virginie, Raymond, Stéphanie, Jeulin, Hélène, Alloui, Chakib, Yerly, Sabine, Pallier, Coralie, Reigadas, Sandrine, Signori-Schmuck, Anne, Guigon, Aurélie, Fafi-Kremer, Samira, Haïm-Boukobza, Stéphanie, Mirand, Audrey, Maillard, Anne, Vallet, Sophie, Roussel, Catherine, Assoumou, Lambert, Calvez, Vincent, Flandre, Philippe, Marcelin, Anne-Geneviève, and ANRS Resistance AC11 Group

Subjects
ANRS Resistance AC11 Group, Humans, HIV-1, HIV Infections, Nervous System Diseases, Anti-HIV Agents, Antiretroviral Therapy, Highly Active, Microbial Sensitivity Tests, Viral Load, Drug Resistance, Viral, Genotype, Mutation, Adult, Middle Aged, Female, Male, ARV, CSF, HIV, resistance, Antiretroviral Therapy, Highly Active, Drug Resistance, Viral, Microbiology, Medical Microbiology, Pharmacology and Pharmaceutical Sciences
Abstract

OBJECTIVES: The neurological disorders in HIV-1-infected patients remain prevalent. The HIV-1 resistance in plasma and CSF was compared in patients with neurological disorders in a multicentre study. METHODS: Blood and CSF samples were collected at time of neurological disorders for 244 patients. The viral loads were >50 copies/mL in both compartments and bulk genotypic tests were realized. RESULTS: On 244 patients, 89 and 155 were antiretroviral (ARV) naive and ARV treated, respectively. In ARV-naive patients, detection of mutations in CSF and not in plasma were reported for the reverse transcriptase (RT) gene in 2/89 patients (2.2%) and for the protease gene in 1/89 patients (1.1%). In ARV-treated patients, 19/152 (12.5%) patients had HIV-1 mutations only in the CSF for the RT gene and 30/151 (19.8%) for the protease gene. Two mutations appeared statistically more prevalent in the CSF than in plasma: M41L (P=0.0455) and T215Y (P=0.0455). CONCLUSIONS: In most cases, resistance mutations were present and similar in both studied compartments. However, in 3.4% of ARV-naive and 8.8% of ARV-treated patients, the virus was more resistant in CSF than in plasma. These results support the need for genotypic resistance testing when lumbar puncture is performed.

Published
2015

35. Is vaccine response to SARS-CoV-2 preserved after switching to anti-CD20 therapies in patients with multiple sclerosis or related disorders?

Author

Jeantin, Lina, primary, Abdi, Basma, additional, Soulié, Cathia, additional, Sterlin, Delphine, additional, Maillart, Elisabeth, additional, Beigneux, Ysoline, additional, Hippolyte, Amandine, additional, Belin, Lisa, additional, Marcelin, Anne-Geneviève, additional, Pourcher, Valérie, additional, and Louapre, Céline, additional

Published
2023
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36. Impact of Human Immunodeficiency Virus Type 1 Minority Variants on the Virus Response to a Rilpivirine-Based First-line Regimen

Author

French National Agency for Research on AIDS and Viral Hepatitis (ANRS) AC11 Resistance Study Group, Raymond, Stéphanie, Nicot, Florence, Pallier, Coralie, Bellecave, Pantxika, Maillard, Anne, Trabaud, Mary Anne, Morand-Joubert, Laurence, Rodallec, Audrey, Amiel, Corinne, Mourez, Thomas, Bocket, Laurence, Beby-Defaux, Agnès, Bouvier-Alias, Magali, Lambert-Niclot, Sidonie, Charpentier, Charlotte, Malve, Brice, Mirand, Audrey, Dina, Julia, Le Guillou-Guillemette, Hélène, Marque-Juillet, Stéphanie, Signori-Schmuck, Anne, Barin, Francis, Si-Mohamed, Ali, Fenoel, Véronique Avettand, Roussel, Catherine, Calvez, Vincent, Saune, Karine, Marcelin, Anne Geneviève, Rodriguez, Christophe, Descamps, Diane, and Izopet, Jacques

Published
2018

37. Universal test and treat and the HIV epidemic in rural South Africa: a phase 4, open-label, community cluster randomised trial

Author

Bärnighausen, Till, Herbst, Kobus, Iwuji, Collins, Makowa, Thembisa, Naidu, Kevi, Newell, Marie-Louise, Okesola, Nonhlanhla, de Oliveira, Tulio, Pillay, Deenan, Rochat, Tamsen, Tanser, Frank, Viljoen, Johannes, Zuma, Thembelihle, McGrath, Nuala, Balestre, Eric, Dabis, François, Karcher, Sophie, Orne-Gliemann, Joanna, Plazy, Melanie, Prague, Mélanie, Thiébaut, Rodolphe, Tiendrebeogo, Thierry, Boyer, Sylvie, Donfouet, Hermann, Gosset, Andrea, March, Laura, Protopopescu, Camelia, Spire, Bruno, Calmy, Alexandra, Larmarange, Joseph, Inghels, Maxime, Diallo, Hassimiou, Calvez, Vincent, Derache, Anne, Marcelin, Anne-Geneviève, Dray-Spira, Rosemary, Lert, France, El Farouki, Kamal, Lessells, Richard, Freedberg, Kenneth, Imrie, John, Chaix, Marie-Laure, Newell, Colin, Hontelez, Jan, Bazin, Brigitte, Rekacewicz, Claire, Iwuji, Collins C, Thiebaut, Rodolphe, Dreyer, Jaco, and De Oliveira, Tulio

Published
2018
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39. Extending vaccination periods against human papillomavirus: Lessons from the SARS‐CoV‐2 pandemic.

Author

Calvez, Juliette, Neirynck, Victoire, Marcelin, Anne‐Geneviève, and Jary, Aude

Subjects
GENITAL warts, COVID-19 pandemic, HUMAN papillomavirus, VACCINATION, PATIENTS, MEDICAL personnel, CONIZATION
Abstract

The article discusses the impact of the COVID-19 pandemic on HPV vaccination worldwide, with a specific focus on France. The pandemic has led to disruptions in HPV vaccination programs, resulting in a significant number of teenagers missing out on vaccination. In France, there was a shortfall of over 400,000 undelivered doses of the HPV vaccine between mid-March 2020 and the end of 2021. The article emphasizes the need for efforts to improve HPV vaccine coverage, including catch-up vaccination for older populations. Failure to address the missed vaccinations could lead to a resurgence of HPV-related cancers in the future. [Extracted from the article]

Published
2024
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42. Identification of natural killer markers associated with fatal outcome in COVID-19 patients

Author

Tarantino, Nadine, primary, Litvinova, Elena, additional, Samri, Assia, additional, Soulié, Cathia, additional, Morin, Véronique, additional, Rousseau, Alice, additional, Dorgham, Karim, additional, Parizot, Christophe, additional, Bonduelle, Olivia, additional, Beurton, Alexandra, additional, Miyara, Makoto, additional, Ghillani, Pascale, additional, Mayaux, Julien, additional, Lhote, Raphael, additional, Lacorte, Jean-Marc, additional, Marcelin, Anne-Geneviève, additional, Amoura, Zahir, additional, Luyt, Charles-Edouard, additional, Gorochov, Guy, additional, Guihot, Amélie, additional, and Vieillard, Vincent, additional

Published
2023
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43. Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals

Author

Hubert, Mathieu, primary, Guivel-Benhassine, Florence, additional, Bruel, Timothée, additional, Porrot, Françoise, additional, Planas, Delphine, additional, Vanhomwegen, Jessica, additional, Wiedemann, Aurélie, additional, Burrel, Sonia, additional, Marot, Stéphane, additional, Palich, Romain, additional, Monsel, Gentiane, additional, Diombera, Harouna, additional, Gallien, Sébastien, additional, Lopez-Zaragoza, Jose Luis, additional, Vindrios, William, additional, Taieb, Fabien, additional, Fernandes-Pellerin, Sandrine, additional, Delhaye, Maurine, additional, Laude, Hélène, additional, Arowas, Laurence, additional, Ungeheuer, Marie-Noelle, additional, Hocqueloux, Laurent, additional, Pourcher, Valérie, additional, Prazuck, Thierry, additional, Marcelin, Anne-Geneviève, additional, Lelièvre, Jean-Daniel, additional, Batéjat, Christophe, additional, Lévy, Yves, additional, Manuguerra, Jean-Claude, additional, and Schwartz, Olivier, additional

Published
2023
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44. Prevalence and risk factors of anal human papillomavirus infections among men having sex with men and transgender women in Phnom Penh, Cambodia

Author

Jary, Aude, primary, Cheng, Sokleaph, additional, Marot, Stéphane, additional, Malonga, Gervillien Arnold, additional, Cocherie, Théophile, additional, Wignall, Steve, additional, Calvez, Vincent, additional, Phal, Sophat, additional, Vichet, Kem, additional, Marcelin, Anne-Geneviève, additional, and Delvallez, Gauthier, additional

Published
2023
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45. High rate of Early HEV Seroconversion after Liver Transplantation among Cirrhotic Patients: Should We Test for it?

Author

Mazzola, Alessandra, primary, Todesco, Eve, additional, Ali, Shadia, additional, Bastide, Mathilde, additional, Charlotte, Frederic, additional, Flandre, Philippe, additional, Sayon, Sophie, additional, Houot, Melanie, additional, Calvez, Vincent, additional, Thabut, Dominique, additional, Scatton, Olivier, additional, Marcelin, Anne-Geneviève, additional, and Conti, Filomena, additional

Published
2023
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47. Corrigendum: XAV-19, a swine glyco-humanized polyclonal antibody against SARS-CoV-2 spike receptor-binding domain, targets multiple epitopes and broadly neutralizes variants

Author

Vanhove, Bernard, primary, Marot, Stéphane, additional, So, Ray T., additional, Gaborit, Benjamin, additional, Evanno, Gwénaëlle, additional, Malet, Isabelle, additional, Lafrogne, Guillaume, additional, Mevel, Edwige, additional, Ciron, Carine, additional, Royer, Pierre-Joseph, additional, Lheriteau, Elsa, additional, Raffi, François, additional, Bruzzone, Roberto, additional, Mok, Chris Ka Pun, additional, Duvaux, Odile, additional, Marcelin, Anne-Geneviève, additional, and Calvez, Vincent, additional

Published
2023
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48. Phylodynamics of SARS-CoV-2 in France, Europe and the world in 2020

Author

Coppée, Romain, primary, Blanquart, François, additional, Jary, Aude, additional, Leducq, Valentin, additional, Ferré, Valentine Marie, additional, Franco Yusti, Anna Maria, additional, Daniel, Léna, additional, Charpentier, Charlotte, additional, Lebourgeois, Samuel, additional, Zafilaza, Karen, additional, Calvez, Vincent, additional, Descamps, Diane, additional, Marcelin, Anne-Geneviève, additional, Visseaux, Benoit, additional, and Bridier-Nahmias, Antoine, additional

Published
2023
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49. SARS-CoV-2 variant-dependent inflammasome activation

Author

Teyssou, Elisa, primary, Marot, Stephane, additional, Gothland, Adelie, additional, Malet, Isabelle, additional, Zafilaza, Karen, additional, Leducq, Valentin, additional, Cocherie, Theophile, additional, Todesco, Eve, additional, Soulie, Cathia, additional, Marcelin, Anne Geneviève, additional, and Calvez, Vincent, additional

Published
2023
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