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3 results on '"María José Jiménez-Martín"'

1. Sobresedación Zero como herramienta de confort, seguridad y gestión en la unidades de cuidados intensivos

Author

J. Caballero, M. García-Sánchez, E. Palencia-Herrejón, T. Muñoz-Martínez, J.M. Gómez-García, I. Ceniceros-Rozalén, Roser Anglés Coll, José Antonio Acosta Escribano, Miguel Ángel Alcalá Llorente, Rafael Barrientos Vega, Ana Bejar Delgado, Antonio Luis Blesa Malpica, Alfonso Bonet Saris, David Cabestrero Alonso, Mª Isabel Ceniceros Rozalén, Carlos Chamorro Jambrina, Isabel Cherta Vivien, Frutos del Nogal Sáez, José Luis Escalante Cobo, Claudio García Alfaro, Francisco Javier Gil Sánchez, Carolina Giménez-Esparza Vich, Víctor González Sanz, Paloma González Arenas, Teodoro Grau Carmona, José Eugenio Guerrero Sanz, Jorge Ibáñez Juvé, Antonio Jareño Chaumel, Manuel Jiménez Lendínez, María José Jiménez Martín, Antonio Lesmes Serrano, José Ángel Lorente Balanza, José Luis Martínez Melgar, Juan Carlos Montejo González, Tomás Muñoz Martínez, Eduardo Palencia Herrejón, Mercedes Palomar Martínez, Cándido Pardo Rey, Hipólito Pérez Moltó, Ferran Roche Campo, Miguel Ángel Romera Ortega, Rafael Ruiz de Luna González, José Ángel Sánchez-Izquierdo Riera, Alberto Sandiumenge Camps, José Alberto Silva Obregón, Herminia Torrado Santos, Pedro Galdos Anuncibay, Ana María Del Saz Ortiz, Jesús Caballero López, Manuela García Sánchez, Mª Belén Estébanez Montiel, Inmaculada Alcalde Mayayo, Luis Yuste Domínguez, José Manuel Gómez García, Susana Temprano Vázquez, Aaron Blandino Ortiz, María Antonia Estecha Foncea, Lucía López Amor, Itziar Hurlé Peláez, Amélie Marie Solange Le Gall, Mariana Isabel Jorge De Almeida e Silva, Elena Bisbal Andrés, Lourdes Fisac Cuadrado, Cristina Ferri Riera, Lorenzo López Pérez, Gabriel Jesús Moreno González, Vanesa Arauzo Rojo, Elena Ruiz-Escribano Taravilla, Chiara Raffaella Caciano Reátegui, Miguel Ángel González Gallego, Sara Rossich Andreu, Ana María Navas Pérez, Federico Minaya González, Miguel Ángel Rodríguez Yago, María Barber Ansón, Amaia Martiarena Orce, José Lorenzo Labarta Monzón, Rocío Almaraz Velarde, Cristina Muñoz Esteban, Ana Vallejo de la Cueva, Joana Domingo Marco, Tatiana García Rodríguez San Miguel, Sara Alcántara Carmona, Oriol Plans Galván, Juan Diego Jiménez Delgado, Mónica García Simón, Amparo Cabanillas Carrillo, Francisco José Guerrero Gómez, María Riera Sagrera, Laura Bellver Bosch, Helena Dominguez Aguado, Dacil María Parrilla Toribio, Alejandra Virgós Pedreira, David Mosquera Rodríguez, Manuela Fernández Arroyo, Susana González Prado, Laura Sayagués Moreira, Luis Alfonso Marcos Prieto, Jesús Priego Sanz, Aída Fernández Ferreira, Mercedes Ibarz Villamayor, Marcela Patricia Hómez Guzman, Ana Abella Álvarez, Federico Gordo Vidal, Vanessa Blazquez Alcaide, Carolina Fuertes Schott, María Aranda Pérez, Gloria María Valle Fernández, Lorena Zoila Peiró Ferrando, Francisca Inmaculada Pino Sánchez, Sulamita Carvalho Brugger, Africa Carmen Lores Obradors, and Inmaculada de Dios Chacón

Subjects
business.industry, Zero (complex analysis), MEDLINE, 030208 emergency & critical care medicine, Critical Care and Intensive Care Medicine, medicine.disease, Intensive care unit, law.invention, 03 medical and health sciences, 0302 clinical medicine, 030228 respiratory system, law, Medicine, Medical emergency, business
Published
2020
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2. Oversedation Zero as a tool for comfort, safety and management in the intensive care unit

Author

José Antonio Acosta Escribano, María Barber Ansón, I. Ceniceros-Rozalén, José Alberto Silva Obregón, Oriol Plans Galván, Francisco José Guerrero Gómez, Víctor González Sanz, Rafael Ruiz de Luna González, José Lorenzo Labarta Monzón, Lorenzo López Pérez, Ana María Navas Pérez, Susana González Prado, Alberto Sandiumenge Camps, Laura Sayagués Moreira, Manuel Jiménez Lendínez, Antonio Lesmes Serrano, Luis Yuste Domínguez, Federico Gordo Vidal, Mariana Isabel Jorge De Almeida e Silva, Lucía López Amor, Mª Isabel Ceniceros Rozalén, María José Jiménez Martín, Federico Minaya González, Mercedes Ibarz Villamayor, Lourdes Fisac Cuadrado, Jesús Caballero López, Helena Dominguez Aguado, Cristina Esteban, M. García-Sánchez, Juan Diego Jiménez Delgado, Inmaculada de Dios Chacón, Miguel Ángel Rodríguez Yago, J.M. Gómez-García, José Manuel Gómez García, Sara Alcántara Carmona, Cristina Ferri Riera, Lorena Zoila Peiró Ferrando, Ana María Del Saz Ortiz, Marcela Patricia Hómez Guzman, Claudio García Alfaro, Teodoro Grau Carmona, Mónica García Simón, Ana Vallejo de la Cueva, David Cabestrero Alonso, Cándido Pardo Rey, Antonio Luis Blesa Malpica, Sulamita Carvalho Brugger, E Palencia-Herrejón, Amparo Cabanillas Carrillo, María Antonia Estecha Foncea, Inmaculada Alcalde Mayayo, Vanessa Blazquez Alcaide, José Eugenio Guerrero Sanz, Manuela García Sánchez, Ana Bejar Delgado, Ana Abella Álvarez, Miguel Ángel González Gallego, Africa Carmen Lores Obradors, Miguel Ángel Alcalá Llorente, Miguel Ángel Romera Ortega, Antonio Jareño Chaumel, Chiara Raffaella Caciano Reátegui, María Riera Sagrera, Gabriel Jesús Moreno González, Mª Belén Estébanez Montiel, Semicyuc, Julio Caballero, Hipólito Pérez Moltó, Rocío Almaraz Velarde, Carolina Giménez-Esparza Vich, Joana Domingo Marco, Vanesa Arauzo Rojo, Amélie Marie Solange Le Gall, Sara Rossich Andreu, Eduardo Palencia Herrejón, Francisca Pino Sánchez, Aída Fernández Ferreira, Frutos del Nogal Sáez, Roser Anglés Coll, Jesús Priego Sanz, Jorge Ibáñez Juvé, Gloria María Valle Fernández, Herminia Torrado Santos, Francisco Javier Gil Sánchez, Luis Alfonso Marcos Prieto, miembros del Gtsad, Tatiana García Rodríguez San Miguel, Rafael Barrientos Vega, Carolina Fuertes Schott, José Luis Martínez Melgar, María Aranda Pérez, Carlos Chamorro Jambrina, Dacil María Parrilla Toribio, Mercedes Palomar Martínez, Elena Ruiz-Escribano Taravilla, Elena Bisbal Andrés, Amaia Martiarena Orce, Isabel Cherta Vivien, Manuela Fernández Arroyo, Alfonso Bonet Saris, Itziar Hurlé Peláez, Tomás Muñoz Martínez, José Ángel Sánchez-Izquierdo Riera, Alejandra Virgós Pedreira, Paloma González Arenas, Ferran Roche Campo, José Ángel Lorente Balanza, Susana Temprano Vázquez, Juan Carlos Montejo González, T. Muñoz-Martínez, David Mosquera Rodríguez, Aaron Blandino Ortiz, Laura Bellver Bosch, José Luis Escalante Cobo, and Pedro Galdos Anuncibay

Subjects
Protocol (science), medicine.medical_specialty, Teamwork, business.industry, Critically ill, media_common.quotation_subject, Sedation, 030208 emergency & critical care medicine, Intensive care unit, law.invention, 03 medical and health sciences, 0302 clinical medicine, Quality of life (healthcare), 030228 respiratory system, Multidisciplinary approach, law, Medicine, Delirium, medicine.symptom, business, Intensive care medicine, media_common
Abstract

Sedation is necessary in the management of critically ill patients, both to alleviate suffering and to cure patients with diseases that require admission to the intensive care unit. Such sedation should be appropriate to the patient needs at each timepoint during clinical evolution, and neither too low (undersedation) nor too high (oversedation). Adequate sedation influences patient comfort, safety, survival, subsequent quality of life, bed rotation of critical care units and costs. Undersedation is detected and quickly corrected. In contrast, oversedation is silent and difficult to prevent in the absence of management guidelines, collective awareness and teamwork. The Zero Oversedation Project of the Sedation, Analgesia and Delirium Working Group of the Spanish Society of Intensive and Critical Care Medicine and Coronary Units aims to offer a practical teaching and collective awareness tool for ensuring patient comfort, safety and management with a view to optimizing the clinical outcomes and minimizing the deleterious effects of excessive sedation. The tool is based on a package of measures that include monitoring pain, analgesia, agitation, sedation, delirium and neuromuscular block, keeping patients pain-free, performing dynamic sedation according to clinical objectives, agreeing upon the multidisciplinary protocol to be followed, and avoiding deep sedation where not clinically indicated.

Published
2020
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3. Ceftazidime-Avibactam as Salvage Therapy for Infections Caused by Carbapenem-Resistant Organisms

Author

Juan Carlos Ramos Ramos, Michael Osthoff, Cameron J Jeremiah, N. Benito, Julián Torre-Cisneros, Bojana Beović, Marta Mora-Rillo, Isabel Machuca, Michel Wolff, Enrique Navas, Belén Loeches, José Antonio Martínez, Raúl Gilarranz, María José Jiménez-Martín, Marina Rodríguez, Miguel Sánchez-García, Maddalena Giannella, J.C. Pozo, Yehuda Carmeli, Elizabeth Temkin, Pierluigi Viale, [Temkin, Elizabeth] Tel Aviv Sourasky Med Ctr, Dept Epidemiol & Prevent Med, Tel Aviv, Israel, [Carmeli, Yehuda] Tel Aviv Sourasky Med Ctr, Dept Epidemiol & Prevent Med, Tel Aviv, Israel, [Beovic, Bojana] Univ Med Ctr Ljubljana, Dept Infect Dis, Ljubljana, Slovenia, [Benito, Natividad] Hosp Santa Creu & Sant Pau, Dept Med, Infect Dis Unit, Barcelona, Spain, [Benito, Natividad] Univ Autonoma Barcelona, Inst Invest Biomed St Pau, Barcelona, Spain, [Giannella, Maddalena] Univ Bologna, S Orsola Malpighi Hosp, Dept Med & Surg Sci, Infect Dis Unit, Bologna, Italy, [Gilarranz, Raul] Hosp Univ Gran Canaria Doctor Negrin, Dept Clin Microbiol, Las Palmas Gran Canaria, Spain, [Jeremiah, Cameron] St Vincents Hosp, Dept Infect Dis, Melbourne, Vic, Australia, [Loeches, Belen] Hosp Univ La Paz IdiPAZ, Infect Dis Unit, Madrid, Spain, [Mora-Rillo, Marta] Hosp Univ La Paz IdiPAZ, Infect Dis Unit, Madrid, Spain, [Ramos Ramos, Juan Carlos] Hosp Univ La Paz IdiPAZ, Infect Dis Unit, Madrid, Spain, [Torre-Cisneros, Julian] Hosp Univ Reina Sofia, Dept Infect Dis, Cordoba, Spain, [Machuca, Isabel] Hosp Univ Reina Sofia, Dept Infect Dis, Cordoba, Spain, [Torre-Cisneros, Julian] Univ Cordoba, Inst Maimonides Invest Biomed, Cordoba, Spain, [Machuca, Isabel] Univ Cordoba, Inst Maimonides Invest Biomed, Cordoba, Spain, [Jose Jimenez-Martin, Maria] Hosp Clin San Carlos, Crit Care Dept, Madrid, Spain, [Sanchez-Garcia, Miguel] Hosp Clin San Carlos, Crit Care Dept, Madrid, Spain, [Antonio Martinez, Jose] Univ Barcelona, IDIBAPS, Hosp Clin, Dept Infect Dis, Barcelona, Spain, [Navas, Enrique] Hosp Ramon & Cajal, Dept Infect Dis, Madrid, Spain, [Osthoff, Michael] Univ Basel Hosp, Div Infect Dis & Hosp Epidemiol, Basel, Switzerland, [Carlos Pozo, Juan] Hosp Univ Reina Sofia, Dept Crit Care Med, Cordoba, Spain, [Rodriguez, Marina] Hosp Univ Reina Sofia, Dept Crit Care Med, Cordoba, Spain, [Viale, Pierluigi] Alma Mater Studiorum Univ Bologna, Dept Med Surg Sci, Bologna, Italy, [Wolff, Michel] Ctr Hosp Univ Bichat Claude Bernard, AP HP, Paris, France, [Wolff, Michel] Univ Paris Diderot, Paris, France, [Carmeli, Yehuda] Tel Aviv Univ, Sackler Sch Med, Tel Aviv, Israel, AstraZeneca, Ministerio de Economia y Competitividad, Instituto de Salud Carlos III, and European Development Regional Fund (ERDF)

Subjects
0301 basic medicine, Male, Antibiotics, Salvage therapy, Bacteremia, medicine.disease_cause, Ceftazidime, Medical microbiology, Plus metronidazole, Pharmacology (medical), Blood-stream infections, Case report form, ceftazidime-avibactam, case series, Klebsiella-pneumoniae, Double-blind, Klebsiella oxytoca, Middle Aged, Anti-Bacterial Agents, Exact test, Drug Combinations, Klebsiella pneumoniae, Infectious Diseases, Combination, Pseudomonas aeruginosa, Female, Safety, medicine.drug, medicine.medical_specialty, Efficacy, medicine.drug_class, 030106 microbiology, carbapenem resistance, Microbial Sensitivity Tests, Clinical Therapeutics, 03 medical and health sciences, Enterobacteriaceae, Internal medicine, medicine, Humans, Colistin-resistant, Aged, Pharmacology, Salvage Therapy, business.industry, Ceftazidime/avibactam, Clinical trial, Carbapenems, business, Azabicyclo Compounds
Abstract

Ceftazidime-avibactam (CAZ-AVI) is a recently approved β-lactam–β-lactamase inhibitor combination with the potential to treat serious infections caused by carbapenem-resistant organisms. Few patients with such infections were included in the CAZ-AVI clinical trials, and clinical experience is lacking. We present a case series of patients with infections caused by carbapenem-resistant Enterobacteriaceae (CRE) or Pseudomonas aeruginosa (CRPa) who were treated with CAZ-AVI salvage therapy on a compassionate-use basis. Physicians who had prescribed CAZ-AVI completed a case report form. We used descriptive statistics to summarize patient characteristics and treatment outcomes. We used the Wilcoxon rank sum test and Fisher's exact test to compare patients by treatment outcome. The sample included 36 patients infected with CRE and two with CRPa. The most common infections were intra-abdominal. Physicians categorized 60.5% of patients as having life-threatening infections. All but two patients received other antibiotics before CAZ-AVI, for a median of 13 days. The median duration of CAZ-AVI treatment was 16 days. Twenty-five patients (65.8%) concurrently received other antibiotics to which their pathogen was nonresistant in vitro . Twenty-eight patients (73.7%, 95% confidence interval [CI], 56.9 to 86.6%) experienced clinical and/or microbiological cure. Five patients (20.8%) with documented microbiological cure died, whereas 10 patients (71.4%) with no documented microbiological cure died ( P = 0.01). In three-quarters of cases, CAZ-AVI (alone or combined with other antibiotics) cured infections caused by carbapenem-resistant organisms, 95% of which had failed previous therapy. Microbiological cure was associated with improved survival. CAZ-AVI shows promising clinical results for infections for which treatment options are limited.

Published
2016

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