1. Cirrhosis, liver transplantation and HIV infection are risk factors associated with hepatitis E virus infection.
- Author
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Mar Riveiro-Barciela, María Buti, María Homs, Isabel Campos-Varela, Carmen Cantarell, Manuel Crespo, Lluís Castells, David Tabernero, Josep Quer, Rafael Esteban, and Francisco Rodriguez-Frías
- Subjects
Medicine ,Science - Abstract
Acute and chronic hepatitis E have been associated with high mortality and development of cirrhosis, particularly in solid-organ recipients and patients infected by human immunodeficiency virus. However, data regarding the epidemiology of hepatitis E in special populations is still limited.Investigate seroprevalence and possible factors associated with HEV infection in a large cohort of immunosuppressed patients.Cross-sectional study testing IgG anti-HEV in serum samples from 1373 consecutive individuals: 332 liver-transplant, 296 kidney-transplant, 6 dual organ recipients, 301 non-transplanted patients with chronic liver disease, 238 HIV-infected patients and 200 healthy controls.IgG anti-HEV was detected in 3.5% controls, 3.7% kidney recipients, 7.4% liver transplant without cirrhosis and 32.1% patients who developed post-transplant cirrhosis (p
- Published
- 2014
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