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BACKGROUND: Eosinophilic esophagitis is a chronic inflammatory disease characterized by infiltration of eosinophils at the level of the esophageal epithelium and is one of the conditions to be evaluated in adults with dysphagia and food impaction. In recent years, there has been an increase in case reports predominantly in western medical literature. In Colombia there are few cases reported with this condition, so there is no clear the prevalence about this disease. CLINICAL CASE: A 48-year-old male patient with heartburn, dysphagia and episodes of alimentary impaction, diagnosed by antecedents, symptoms, endoscopic findings and histological confirmation. Treatment with proton pump inhibitors and dietary restrictions was started for four weeks with a follow-up of 6 months, with which the patient responded satisfactorily with permanent relief of symptoms and without complications related to the treatment. CONCLUSIONS: In Colombia the exact prevalence of eosinophilic esophagitis is not known; however, it is considered an emerging disease. Therefore, it should be included in the differential diagnosis of dysphagia in adults, which allows establishing the timely diagnosis and treatment, the relief of symptoms and, consequently, the improvement of the patient's quality of life. [ABSTRACT FROM AUTHOR]

Solenodons are insectivores found only in Hispaniola and Cuba, with a Mesozoic divergence date versus extant mainland mammals. Solenodons are the oldest lineage of living eutherian mammal for which a mitogenome sequence has not been reported. We determined complete mitogenome sequences for six Hispaniolan solenodons (Solenodon paradoxus) using next-generation sequencing. The solenodon mitogenomes were 16,454–16,457 bp long and carried the expected repertoire of genes. A mitogenomic phylogeny confirmed the basal position of solenodons relative to shrews and moles, with solenodon mitogenomes estimated to have diverged from those of other mammals ca. 78 Mya. Control region sequences of solenodons from the northern (n = 3) and southern (n = 5) Dominican Republic grouped separately in a network, withFST= 0.72 (p = 0.036) between north and south. This regional genetic divergence supports previous morphological and genetic reports recognizing northern (S. p. paradoxus) and southern (S. p. woodi) subspecies in need of separate conservation plans. [ABSTRACT FROM PUBLISHER]