1. Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome
- Author
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Salehpour, S., Manzor-Al-Ajdad, O., Samani, E. N., and Ashraf Abadi
- Subjects
lcsh:R5-920 ,Gynecology and Female Infertility ,endocrine system diseases ,polycystic ovary syndrome ,homocysteine blood ,cardiovascular disease ,nutritional and metabolic diseases ,Original Article ,lcsh:Medicine (General) ,female genital diseases and pregnancy complications ,Endocrinology and Metabolism - Abstract
Background To determine the level of plasma homocysteine in patients with polycystic ovary syndrome (PCOS) compared with healthy controls. Materials and Methods In this prospective case-control study on 85 PCOS women and 83 controls matched by body mass index (BMI), homocysteine levels were assessed. Results The mean level of homocysteine was 16.25 ± 11.94 μmol/L in patients with PCOS and 11.58 ± 3.82 μmol/L in controls (p=0.002). Patients with PCOS had a significantly higher risk for hyperhomocysteinemia compared with BMI-matched control women. Conclusion These data suggest that homocysteine levels are elevated in the PCOS population. Further studies are needed to characterize this relationship.
- Published
- 2011