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The Asteraceae family is one of the largest plant families within southern Africa, providing key information relating to ecological changes in vegetation structure and climate. This paper specifically aimed to analyse two coastal species namely the Osteospermum moniliferum (Coastal thicket affinity) and the Metalasia muricata (Fynbos affinity) within the Cape Floristic Region. The results of this project found three significantly different pollen morphology types that can be used to differentiate between the two selected species, namely the number of spines between each colpi, the size of the pollen grains, as well as the cap length on each spine. The next step was to then apply this knowledge to the Eilandvlei sequence (Quick et al. 2018) situated along the southern Cape coast of South Africa. The Asteraceae family was identified as one of the most dominant taxa within this assemblage, with the High Spine group accounting for 55% of the total Asteraceae that were originally counted, providing no ecological or climate information. Applying the new classifications indicated that the Coastal thicket ecological group was underrepresented within the assemblage due to the lack of a fine scale classification. Neighbouring studies along the southern Cape coast as well as those across the different South African biomes also lack the classifications needed to differentiate among the Asteraceae more fully, highlighting the need for a re-examination of these records to provide greater ecological insight into the past climate data that could potentially aid scientists, local stakeholders, and policymakers on conservation efforts within key biodiversity hotspots., The 28th IUGG General Assembly (IUGG2023) (Berlin 2023)

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Cloud workload prediction is a very critical task for elastic scaling, because cloud manager decides what configuration sequence is to be considered for resource provisioning. Matching the demand guarantees Service Level Agreement condition (SLA) and Quality of Service (QoS) performance. Many techniques have been used in literature for workload prediction that show accepted accuracy but all of them have some limitation and challenges, like modeling architecture, training, validation and tuning. In this work we propose a subjective analytical model that studies the cloud workload, and formulates a statistical/mathematical model to describe the workload behavior. Workloads are generated from different sources, such as regular applications running on cloud, or data log from Internet of Things (IoT) systems to monitor and control physical systems. Real time cyber-physical system requires high accuracy provisioning for resources to prevent any performance degradation. Predicting and modeling different types of cloud workloads enhances system performance and increases its accuracy. This work considers cloud workload modeling with excellent prediction values and less training cost compared with other methods.

The coronavirus disease 2019 (COVID-19) pandemic has taken an unprecedented global toll and vaccination is needed to restore healthy living. Timely inclusion of children in vaccination trials is critical. We surveyed caregivers of children seeking care in 17 Emergency Departments (ED) across 6 countries during the peak of the pandemic to identify factors associated with intent to participate in COVID-19 vaccine trials. Questions about child and parent characteristics, COVID-19 expressed concerns and parental attitudes toward participation in a trial were asked.Of 2768 completed surveys, 18.4% parents stated they would enroll their child in a clinical trial for a COVID-19 vaccine and 14.4% would agree to a randomized placebo-controlled study. Factors associated with willingness to participate were parents agreeing to enroll in a COVID-19 vaccine trial themselves (Odds Ratio (OR) 32.9, 95% Confidence Interval (CI) (21.9-51.2)) having an older child (OR 1.0 (1.0-1.01)), having children who received all vaccinations based on their country schedule (OR 2.67 (1.35-5.71)) and parents with high school education or lower (OR 1.79 (1.18-2.74)). Mothers were less likely to enroll their child in a trial (OR 0.68 (0.47-0.97)). Only one fifth of families surveyed will consider enrolling their child in a vaccine trial. Parental interest in participation, history of vaccinating their child, and the child being older all are associated with parents allowing their child to participate in a COVID vaccine trial. This information may help decision-makers and researchers shape their strategies for trial design and participation engagement in upcoming COVID19 vaccination trials.

Objectives To develop and validate a prediction rule to identify well-appearing febrile infants aged = 0.6 ng/mL) and C reactive protein (>= 20 mg/L) as risk factors. The absence of any risk factor had a sensitivity of 96.0% (95% CI 80.5% to 99.3%), a negative predictive value of 99.4% (95% CI 96.4% to 99.9%) and a specificity of 32.9% (95% CI 28.8% to 37.3%) for ruling out an IBI. Applying it in the 449 infants of the validation set (IBI rate 4.9%), sensitivity, negative predictive value and specificity were 100% (95% CI 87.1% to 100%), 100% (95% CI 97.3% to 100%) and 29.7% (95% CI 25.8% to 33.8%), respectively. Conclusion This prediction rule accurately identified well-appearing febrile infants aged

OBJECTIVE: To determine if caregivers of children presenting to pediatric emergency departments (EDs) during the COVID-19 pandemic are delaying presenting to care for fear of contracting COVID-19. METHODS: This was a pre-planned secondary analysis of a cross-sectional survey study of caregivers accompanying their children aged 0-19 years to 16 pediatric EDs in 5 countries from May to June 2020. An anonymous online survey, completed by caregivers via RedCAP, included caregiver and child demographics, presenting complaints, if they delayed presentation and whether symptoms worsened during this interval, as well as caregiver concern about the child or caregiver having COVID-19 at the time of ED visit. RESULTS: Of 1543 caregivers completing the survey, 287 (18.6%) reported a delay in seeking ED care due to concerns of contracting COVID-19 in the hospital. Of those, 124 (43.2%) stated their child's symptoms worsened during the waiting interval. Caregiver relationship to child [mother] (OR 1.85, 95% CI 1.27-2.76), presence of chronic illness in child (OR 1.78. 95% CI 1.14-2.79), younger age of caregiver (OR 0.965, 95% CI 0.943-0.986), and caregiver concerns about lost work during the pandemic (OR 1.08, 95% CI 1.04-1.12) were independently associated with a COVID-19-related delayed presentation in multivariable regression analysis. CONCLUSIONS: Almost one in five caregivers reported delaying ED presentation for their ill or injured child specifically due to fear of contracting COVID-19 while in hospital, with mothers, younger caregivers, caregivers of children with chronic illness, and those concerned about lost work more likely to report delaying ED presentation.

Resumen: Introducción: La asertividad se define como el conjunto de conductas emitidas por una persona en un contexto interpersonal, en base a la expresión de sentimientos, actitudes, deseos, opiniones o derechos de esa persona de un modo directo, firme y honesto, respetando al mismo tiempo los de otras personas. Objetivo: El objetivo del presente estudio fue analizar el efecto de un programa de entrenamiento CHIIT en los niveles de asertividad en adolescentes. Método: Se trata de un estudio cuantitativo longitudinal, en el que la muestra estaba formada por 111 adolescentes, con un grupo experimental (GE n = 65) y grupo control (GC n = 46). La asertividad se midió con el test publicado en el libro ‘‘Haga oír su voz sin gritar’’ de Shelton y Burton. El GE fue sometido a 20 minutos de CHIIT con intensidad monitorizada durante las 2 sesiones semanales de EF. Mientras que el GC siguió con sus clases normales impartidas por su profesor de Educación Física. Como análisis se usó ANOVA de medidas repetidas 2 (Grupo) X 2 (Tiempo) del modelo lineal general. Resultados y discusión: Nuestros resultados mostraron que no hubo diferencias significativas en la asertividad tras el programa CHIIT. Quizás fuese necesario juegos de un carácter más socializador y de toma de decisiones grupales para trabajar esta variable de forma más específica. Conclusiones: Se concluye que este programa de CHIIT no mejora la asertividad de los adolescentes. Se sugiere, por tanto, que el tiempo y/o estímulo de intervención del programa pudo no ser el adecuado., Introduction: Assertiveness is defined as the set of behaviors emitted by a person in an interpersonal context, based on the expression of feelings, attitudes, wishes, opinions or rights of that person in a direct, firm and honest way, respecting the same other people's time. Aim: The objective of the present study was to analyze the effect of a CHIIT training program on assertiveness levels in adolescents. Method: This is a longitudinal quantitative study, in which the sample consisted of 111 adolescents, with an experimental group (GE n = 65) and control group (GC n = 46). Assertiveness was measured with the test published in the book "Make your voice heard without screaming" by Shelton and Burton. The GE underwent 20 minutes of CHIIT with monitored intensity during the 2 weekly sessions of EF. While the GC continued with its normal classes taught by its Physical Education teacher. As analysis, repeated measures ANOVA 2 (Group) X 2 (Time) of the general linear model was used. Results & discussion: Our results showed that there were no significant differences in assertiveness after the CHIIT program. Perhaps games of a more socializing and group decision-making nature were necessary to work this variable more specifically. Conclusions: It is concluded that this CHIIT program does not improve the assertiveness of adolescents. Therefore, it is suggested that the program intervention time and / or stimulus may not be adequate., Resumo: Introdução: Assertividade é definida como o conjunto de comportamentos emitidos por uma pessoa em um contexto interpessoal, com base na expressão de sentimentos, atitudes, desejos, opiniões ou direitos dessa pessoa de maneira direta, firme e honesta, respeitando o mesmo tempo de outras pessoas. Objectivos: O objetivo do presente estudo foi analisar o efeito de um programa de treinamento CHIIT nos níveis de assertividade em adolescentes. Método: Estudo quantitativo longitudinal, em que a amostra foi composta por 111 adolescentes, com grupo experimental (GE n = 65) e grupo controle (GC n = 46). A assertividade foi medida com o teste publicado no livro "Faça sua voz ser ouvida sem gritar" por Shelton e Burton. O GE foi submetido a 20 minutos de CHIIT com intensidade monitorada durante as 2 sessões semanais de FE. Enquanto o GC continuava com as aulas normais ministradas pelo professor de Educação Física. Como análise, foram utilizadas medidas repetidas ANOVA 2 (Grupo) X 2 (Tempo) do modelo linear geral. Resultados e discussão: Nossos resultados mostraram que não houve diferenças significativas na assertividade após o programa CHIIT. Talvez jogos de natureza mais socializadora e de tomada de decisão em grupo fossem necessários para trabalhar essa variável mais especificamente. Conclusões: Conclui-se que este programa CHIIT não melhora a assertividade dos adolescentes. Portanto, sugere-se que o tempo de intervenção do programa e / ou estímulo não sejam adequados.

PURPOSE: This study determined the predictors of caregivers' willingness to accept an accelerated regulatory process for the development of vaccines against coronavirus disease 2019 (COVID-19). METHODS: An international cross-sectional survey was administered to 2557 caregivers of children in 17 pediatric emergency departments (EDs) across 6 countries from March 26, 2020, to June 30, 2020. Caregivers were asked to select 1 of 4 choices with which they most agreed regarding a proposed COVID-19 vaccine-approval process, in addition to questions regarding demographic characteristics, the ED visit, and attitudes about COVID-19. Univariate analyses were conducted using the Mann-Whitney U test for comparing non-normally distributed continuous variables, an independent t test for comparing normally distributed continuous variables, and a ?(2) or Fisher exact test for categorical variables. Multivariate logistic regression analysis was used for determining independent factors associated with caregivers' willingness to accept abridged development of a COVID-19 vaccine. A P value of

[EN] Human milk is a complex fluid composed of a wide variety of substances. The data currently available suggest that, under physiological conditions, the number and concentration of these substances can vary depending on many factors (genetic background, ethnicity, geographic location, diet, postpartum time...). In this context, the aim of the INSPIRE project was to know the natural variability in the composition of human milk among healthy women that differ in their geographical location, ethnicity, diet and socio-economic situation. This article shows the general design of the study and the results obtained regarding human milk oligosaccharides (HMOs), one of the major components in this biological fluid and whose biological functions are very relevant to infant health. The results show a clear effect of the cohort (p, [ES] La leche humana es un fluido complejo, compuesto por una amplia variedad de sustancias, entre las que se incluyen nutrientes y otros componentes bioactivos. Los datos disponibles en la actualidad sugieren que, en condiciones fisiológicas, el número y la concentración de estas sustancias pueden variar en función de muchos factores (base genética, etnia, localización geográfica, dieta, tiempo posparto...). En este contexto, el objetivo del proyecto internacional INSPIRE era conocer la variabilidad natural en la composición de la leche humana entre mujeres sanas que difieren en cuanto a su localización geográfica, etnia, dieta y situación socioeconómica, que se reflejan en la existencia de grandes diferencias en los factores ambientales, microbiológicos y socioculturales relacionados con la crianza y el entorno del recién nacido. En este artículo se muestra el diseño general del estudio y los resultados obtenidos con los oligosacáridos de la leche humana (HMO), uno de los componentes mayoritarios en este fluido biológico, con funciones biológicas muy relevantes para la salud infantil. Los resultados muestran un claro efecto de la cohorte (p

Mintegi, Santiago/0000-0002-2342-8881; Gomez, Borja/0000-0001-6542-4494; Nijman, Ruud Gerard/0000-0001-9671-8161; Parri, Niccolo/0000-0002-8098-2504; Maconochie, Ian/0000-0001-6319-8550, WOS: 000495095400013, PubMed: 31023707, Objective Research in European Paediatric Emergency Medicine (REPEM) network is a collaborative group of 69 paediatric emergency medicine (PEM) physicians from 20 countries in Europe, initiated in 2006. To further improve paediatric emergency care in Europe, the aim of this study was to define research priorities for PEM in Europe to guide the development of future research projects. Design and Setting We carried out an online survey in a modified three-stage Delphi study. Eligible participants were members of the REPEM network. in stage 1, the REPEM steering committee prepared a list of research topics. in stage 2, REPEM members rated on a 6-point scale research topics and they could add research topics and comment on the list for further refinement. Stage 3 included further prioritisation using the Hanlon Process of Prioritisation (HPP) to give more emphasis to the feasibility of a research topic. Results Based on 52 respondents (response rates per stage varying from 41% to 57%), we identified the conditions 'fever', 'sepsis' and 'respiratory infections', and the processes/interventions 'biomarkers', 'risk stratification' and 'practice variation' as common themes of research interest. the HPP identified highest priority for 4 of the 5 highest prioritised items by the Delphi process, incorporating prevalence and severity of each condition and feasibility of undertaking such research. Conclusions While the high diversity in emergency department (ED) populations, cultures, healthcare systems and healthcare delivery in European PEM prompts to focus on practice variation of ED conditions, our defined research priority list will help guide further collaborative research efforts within the REPEM network to improve PEM care in Europe.

[EN] Human milk is a complex fluid composed of a wide variety of substances. The data currently available suggest that, under physiological conditions, the number and concentration of these substances can vary depending on many factors (genetic background, ethnicity, geographic location, diet, postpartum time...). In this context, the aim of the INSPIRE project was to know the natural variability in the composition of human milk among healthy women that differ in their geographical location, ethnicity, diet and socio-economic situation. This article shows the general design of the study and the results obtained regarding human milk oligosaccharides (HMOs), one of the major components in this biological fluid and whose biological functions are very relevant to infant health. The results show a clear effect of the cohort (p

PubMed ID: 28771410, BACKGROUND AND OBJECTIVES: Identifying international differences in the management of acute pediatric poisonings may help improve the quality of care. The objective of this study was to assess the international variation and appropriateness of gastrointestinal decontamination (GID) procedures performed in children and adolescents who present with acute poisonings to emergency departments. METHODS: This was an international, multicenter, cross-sectional prospective study including children