263 results on '"Manz, Michael"'
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2. Morphologic and molecular analysis of liver injury after SARS-CoV-2 vaccination reveals distinct characteristics
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Uzun, Sarp, Zinner, Carl P., Beenen, Amke C., Alborelli, Ilaria, Bartoszek, Ewelina M., Yeung, Jason, Calgua, Byron, Reinscheid, Matthias, Bronsert, Peter, Stalder, Anna K., Haslbauer, Jasmin D., Vosbeck, Juerg, Mazzucchelli, Luca, Hoffmann, Tobias, Terracciano, Luigi M., Hutter, Gregor, Manz, Michael, Panne, Isabelle, Boettler, Tobias, Hofmann, Maike, Bengsch, Bertram, Heim, Markus H., Bernsmeier, Christine, Jiang, Sizun, Tzankov, Alexandar, Terziroli Beretta-Piccoli, Benedetta, and Matter, Matthias S.
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- 2023
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3. Chronische Diarrhoe und Ulzera duodeni – was steckt dahinter?
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Rebell, Claudia, primary, Bolli, Martin, additional, Reichmann, Jan, additional, Bieg, Christian, additional, and Manz, Michael, additional
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- 2024
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4. Diarrhée chronique et ulcères duodénaux – qu’est-ce qui se cache derrière?
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Rebell, Claudia, primary, Bolli, Martin, additional, Reichmann, Jan, additional, Bieg, Christian, additional, and Manz, Michael, additional
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- 2024
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5. Impact of Overweight and Obesity on Disease Outcome in the Pediatric Swiss Inflammatory Bowel Disease Cohort
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von Graffenried, Thea, Schoepfer, Alain M., Rossel, Jean-Benoit, Greuter, Thomas, Safroneeva, Ekaterina, Godat, Sébastien, Henchoz, Sarah, Vavricka, Stephan R., Sokollik, Christiane, Spalinger, Johannes, Braegger, Christian P., Nydegger, Andreas, Abdelrahman, Karim, Ademi, Gentiana, Aepli, Patrick, Thomas, Amman, Anderegg, Claudia, Antonino, Anca-Teodora, Archanioti, Eva, Arrigoni, Eviano, de Jong, Diana Bakker, Balsiger, Bruno, Bastürk, Polat, Bauerfeind, Peter, Becocci, Andrea, Belli, Dominique, Bengoa, José M., Biedermann, Luc, Binek, Janek, Blattmann, Mirjam, Boehm, Stephan, Boldanova, Tujana, Borovicka, Jan, Braegger, Christian P., Brand, Stephan, Brügger, Lukas, Brunner, Simon, Bühr, Patrick, Burnand, Bernard, Burk, Sabine, Burri, Emanuel, Buyse, Sophie, Cao, Dahlia-Thao, Carstens, Ove, Criblez, Dominique H., Cunningham, Sophie, D’Angelo, Fabrizia, de Saussure, Philippe, Degen, Lukas, Delarive, Joakim, Doerig, Christopher, Dora, Barbara, Drerup, Susan, Egger, Mara, El-Wafa, Ali, Engelmann, Matthias, Felley, Christian, Fliegner, Markus, Fournier, Nicolas, Fraga, Montserrat, Franc, Yannick, Frei, Pascal, Frei, Remus, Fried, Michael, Froehlich, Florian, Furlano, Raoul Ivano, Garzoni, Luca, Geyer, Martin, Girard, Laurent, Girardin, Marc, Golay, Delphine, Good, Ignaz, Bigler, Ulrike Graf, Gysi, Beat, Haarer, Johannes, Halama, Marcel, Haldemann, Janine, Heer, Pius, Heimgartner, Benjamin, Helbling, Beat, Hengstler, Peter, Herzog, Denise, Hess, Cyrill, Heyland, Klaas, Hinterleitner, Thomas, Hirschi, Claudia, Hruz, Petr, Juillerat, Pascal, Khalid-de Bakker, Carolina, Kayser, Stephan, Keller, Céline, Knellwolf, Christina, Knoblauch, Christoph, Köhler, Henrik, Koller, Rebekka, Krieger, Claudia, Künzler, Patrizia, Kusche, Rachel, Lehmann, Frank Serge, Macpherson, Andrew, Maillard, Michel H., Manz, Michael, Marot, Astrid, Meier, Rémy, Meyenberger, Christa, Meyer, Pamela, Michetti, Pierre, Misselwitz, Benjamin, Mosler, Patrick, Mottet, Christian, Müller, Christoph, Müllhaupt, Beat, Musso, Leilla, Neagu, Michaela, Nichita, Cristina, Niess, Jan, Nydegger, Andreas, Obialo, Nicole, Ollo, Diana, Oropesa, Cassandra, Peter, Ulrich, Peternac, Daniel, Petit, Laetitia Marie, Pittet, Valérie, Pohl, Daniel, Porzner, Marc, Preissler, Claudia, Raschle, Nadia, Rentsch, Ronald, Restellini, Alexandre, Restellini, Sophie, Richterich, Jean-Pierre, Ris, Frederic, Risti, Branislav, Ritz, Marc Alain, Rogler, Gerhard, Röhrich, Nina, Rossel, Jean-Benoît, Rueger, Vanessa, Rusticeanu, Monica, Sagmeister, Markus, Saner, Gaby, Sauter, Bernhard, Sawatzki, Mikael, Scharl, Michael, Schelling, Martin, Schibli, Susanne, Schlauri, Hugo, Schluckebier, Dominique, Schmid, Daniela, Schmid, Sybille, Schnegg, Jean-François, Schoepfer, Alain, Seematter, Vivianne, Seibold, Frank, Seirafi, Mariam, Semadeni, Gian-Marco, Senning, Arne, Sokollik, Christiane, Sommer, Joachim, Spalinger, Johannes, Spangenberger, Holger, Stadler, Philippe, Staub, Peter, Staudenmann, Dominic, Stenz, Volker, Steuerwald, Michael, Straumann, Alex, Stulz, Andreas, Sulz, Michael, Tatu, Aurora, Tempia-Caliera, Michela, Thorens, Joël, Truninger, Kaspar, Tutuian, Radu, Urfer, Patrick, Vavricka, Stephan, Viani, Francesco, Vögtlin, Jürg, Von Känel, Roland, Vouillamoz, Dominique, Vulliamy, Rachel, Wiesel, Paul, Wiest, Reiner, Wöhrle, Stefanie, Zamora, Samuel, Zander, Silvan, Zeitz, Jonas, and Zimmermann, Dorothee
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- 2022
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6. Differences in Outcomes Reported by Patients With Inflammatory Bowel Diseases vs Their Health Care Professionals
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Anderegg, Claudia, Bauerfeind, Peter, Beglinger, Christoph, Begré, Stefan, Belli, Dominique, Bengoa, José M., Biedermann, Luc, Bigler, Beat, Binek, Janek, Blattmann, Mirjam, Boehm, Stephan, Borovicka, Jan, Braegger, Christian P., Brunner, Nora, Bühr, Patrick, Burnand, Bernard, Burri, Emanuel, Buyse, Sophie, Cremer, Matthias, Criblez, Dominique H., de Saussure, Philippe, Degen, Lukas, Delarive, Joakim, Doerig, Christopher, Dora, Barbara, Dorta, Gian, Egger, Mara, Ehmann, Tobias, El-Wafa, Ali, Engelmann, Matthias, Ezri, Jessica, Felley, Christian, Fliegner, Markus, Fournier, Nicolas, Fraga, Montserrat, Frei, Pascal, Frei, Remus, Fried, Michael, Froehlich, Florian, Funk, Christian, Furlano, Raoul Ivano, Gallot-Lavallée, Suzanne, Geyer, Martin, Girardin, Marc, Golay, Delphine, Grandinetti, Tanja, Gysi, Beat, Haack, Horst, Haarer, Johannes, Helbling, Beat, Hengstler, Peter, Herzog, Denise, Hess, Cyrill, Heyland, Klaas, Hinterleitner, Thomas, Hiroz, Philippe, Hirschi, Claudia, Hruz, Petr, Iwata, Rika, Jost, Res, Juillerat, Pascal, Keller, Céline, Knellwolf, Christina, Knoblauch, Christoph, Köhler, Henrik, Koller, Rebekka, Krieger-Grübel, Claudia, Kullak-Ublick, Gerd, Künzler, Patrizia, Landolt, Markus, Lange, Rupprecht, Lehmann, Frank Serge, Macpherson, Andrew, Maerten, Philippe, Maillard, Michel H., Manser, Christine, Manz, Michael, Marbet, Urs, Marx, George, Matter, Christoph, Meier, Rémy, Mendanova, Martina, Michetti, Pierre, Misselwitz, Benjamin, Morell, Bernhard, Mosler, Patrick, Mottet, Christian, Müller, Christoph, Müller, Pascal, Müllhaupt, Beat, Münger-Beyeler, Claudia, Musso, Leilla, Nagy, Andreas, Neagu, Michaela, Nichita, Cristina, Niess, Jan, Nydegger, Andreas, Obialo, Nicole, Oneta, Carl, Oropesa, Cassandra, Peter, Ueli, Peternac, Daniel, Petit, Laetitia Marie, Piccoli-Gfeller, Franziska, Pilz, Julia Beatrice, Pittet, Valérie, Raschle, Nadia, Rentsch, Ronald, Restellini, Sophie, Richterich, Jean-Pierre, Rihs, Sylvia, Ritz, Marc Alain, Roduit, Jocelyn, Rogler, Daniela, Rogler, Gerhard, Rossel, Jean-Benoît, Rueger, Vanessa, Saner, Gaby, Sauter, Bernhard, Sawatzki, Mikael, Schäppi, Michela, Scharl, Michael, Scharl, Sylvie, Schelling, Martin, Schibli, Susanne, Schlauri, Hugo, Uebelhart, Sybille Schmid, Schnegg, Jean-François, Schoepfer, Alain, Seibold, Frank, Seirafi, Mariam, Semadeni, Gian-Marco, Semela, David, Senning, Arne, Sidler, Marc, Sokollik, Christiane, Spalinger, Johannes, Spangenberger, Holger, Stadler, Philippe, Steuerwald, Michael, Straumann, Alex, Straumann-Funk, Bigna, Sulz, Michael, Suter, Alexandra, Thorens, Joël, Tiedemann, Sarah, Tutuian, Radu, Vavricka, Stephan, Viani, Francesco, Vögtlin, Jürg, Von Känel, Roland, Vonlaufen, Alain, Vouillamoz, Dominique, Vulliamy, Rachel, Wermuth, Jürg, Werner, Helene, Wiesel, Paul, Wiest, Reiner, Wylie, Tina, Zeitz, Jonas, Zimmermann, Dorothee, Pittet, Valérie E.H., and Simonson, Thomas
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- 2019
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7. Dietary antioxidants and periodontal disease in community-based older Japanese: a 2-year follow-up study
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Iwasaki, Masanori, Moynihan, Paula, Manz, Michael C, Taylor, George W, Yoshihara, Akihiro, Muramatsu, Kanako, Watanabe, Reiko, and Miyazaki, Hideo
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Prevention ,Clinical Research ,Dental/Oral and Craniofacial Disease ,Nutrition ,Oral and gastrointestinal ,Aged ,Antioxidants ,Ascorbic Acid ,Carotenoids ,Disease Progression ,Female ,Follow-Up Studies ,Humans ,Incidence ,Japan ,Male ,Multivariate Analysis ,Periodontal Diseases ,Periodontium ,Poisson Distribution ,Retrospective Studies ,Surveys and Questionnaires ,Tooth ,Vitamin E ,beta Carotene ,Dietary antioxidants ,Periodontal disease ,Longitudinal study ,Elderly ,Medical and Health Sciences ,Nutrition & Dietetics - Abstract
ObjectiveTo investigate the longitudinal relationship between the intake of dietary antioxidants and periodontal disease in community-dwelling older Japanese.DesignA retrospective cohort study, with a follow-up of 2 years (2003-2005). Intakes of dietary antioxidants (vitamin C, vitamin E, α-carotene and β-carotene) were assessed with a validated FFQ. Participants were classified by tertile of antioxidant intake. Full-mouth periodontal status, measured as the clinical attachment level, was recorded at baseline and follow-up examinations. Periodontal disease progression was considered as loss of attachment of 3 mm or greater over the study period at the interproximal site for each tooth. Finally, the number of teeth with periodontal disease progression per person was calculated and was used as the outcome. Poisson regression analysis was conducted, with dietary antioxidants as the main exposure, to estimate their influence on the number of teeth with periodontal disease progression.SettingNiigata City (Japan).SubjectsDentate individuals aged 75 years in 2003, for whom data were available, were included in the analyses (n 264).ResultsA higher intake of dietary antioxidants was inversely associated with the number of teeth with periodontal disease progression, controlling for other variables. The multivariate-adjusted incidence rate ratios in the first, second and third tertiles were 1·00, 0·76 (95 % CI 0·60, 0·97) and 0·72 (95 % CI 0·56, 0·93) for vitamin C; 1·00, 0·79 (95 % CI 0·62, 0·99) and 0·55 (95 % CI 0·42, 0·72), for vitamin E; and 1·00, 1·02 (95 % CI 0·81, 1·29) and 0·73 (95 % CI 0·56, 0·95) for β-carotene.ConclusionsThe study results suggest that higher intake of antioxidants may mitigate periodontal disease in community-dwelling older Japanese.
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- 2013
8. Symptoms of Depression and Anxiety Are Independently Associated With Clinical Recurrence of Inflammatory Bowel Disease
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Anderegg, Claudia, Bauerfeind, Peter, Beglinger, Christoph, Begré, Stefan, Belli, Dominique, Bengoa, José M., Biedermann, Luc, Bigler, Beat, Binek, Janek, Blattmann, Mirjam, Boehm, Stephan, Borovicka, Jan, Braegger, Christian P., Brunner, Nora, Bühr, Patrick, Burnand, Bernard, Burri, Emanuel, Buyse, Sophie, Cremer, Matthias, Criblez, Dominique H., de Saussure, Philippe, Degen, Lukas, Delarive, Joakim, Doerig, Christopher, Dora, Barbara, Dorta, Gian, Egger, Mara, Ehmann, Tobias, El-Wafa, Ali, Engelmann, Matthias, Ezri, Jessica, Felley, Christian, Fliegner, Markus, Fournier, Nicolas, Fraga, Montserrat, Frei, Pascal, Frei, Remus, Fried, Michael, Froehlich, Florian, Funk, Christian, Ivano Furlano, Raoul, Gallot-Lavallée, Suzanne, Geyer, Martin, Girardin, Marc, Golay, Delphine, Grandinetti, Tanja, Gysi, Beat, Haack, Horst, Haarer, Johannes, Helbling, Beat, Hengstler, Peter, Herzog, Denise, Hess, Cyrill, Heyland, Klaas, Hinterleitner, Thomas, Hiroz, Philippe, Hirschi, Claudia, Hruz, Petr, Iwata, Rika, Jost, Res, Juillerat, Pascal, Kessler Brondolo, Vera, Knellwolf, Christina, Knoblauch, Christoph, Köhler, Henrik, Koller, Rebekka, Krieger-Grübel, Claudia, Kullak-Ublick, Gerd, Künzler, Patrizia, Landolt, Markus, Lange, Rupprecht, Serge Lehmann, Frank, Macpherson, Andrew, Maerten, Philippe, Maillard, Michel H., Manser, Christine, Manz, Michael, Marbet, Urs, Marx, George, Matter, Christoph, McLin, Valérie, Meier, Rémy, Mendanova, Martina, Meyenberger, Christa, Michetti, Pierre, Misselwitz, Benjamin, Moradpour, Darius, Morell, Bernhard, Mosler, Patrick, Mottet, Christian, Müller, Christoph, Müller, Pascal, Müllhaupt, Beat, Münger-Beyeler, Claudia, Musso, Leilla, Nagy, Andreas, Neagu, Michaela, Nichita, Cristina, Niess, Jan, Noël, Natacha, Nydegger, Andreas, Obialo, Nicole, Oneta, Carl, Oropesa, Cassandra, Peter, Ueli, Peternac, Daniel, Marie Petit, Laetitia, Piccoli-Gfeller, Franziska, Beatrice Pilz, Julia, Pittet, Valérie, Raschle, Nadia, Rentsch, Ronald, Restellini, Sophie, Richterich, Jean-Pierre, Rihs, Sylvia, Alain Ritz, Marc, Roduit, Jocelyn, Rogler, Daniela, Rogler, Gerhard, Rossel, Jean-Benoît, Sagmeister, Markus, Saner, Gaby, Sauter, Bernhard, Sawatzki, Mikael, Schäppi, Michela, Scharl, Michael, Schelling, Martin, Schibli, Susanne, Schlauri, Hugo, Schmid Uebelhart, Sybille, Schnegg, Jean-François, Schoepfer, Alain, Seibold, Frank, Seirafi, Mariam, Semadeni, Gian-Marco, Semela, David, Senning, Arne, Sidler, Marc, Sokollik, Christiane, Spalinger, Johannes, Spangenberger, Holger, Stadler, Philippe, Steuerwald, Michael, Straumann, Alex, Straumann-Funk, Bigna, Sulz, Michael, Thorens, Joël, Tiedemann, Sarah, Tutuian, Radu, Vavricka, Stephan, Viani, Francesco, Vögtlin, Jürg, Von Känel, Roland, Vonlaufen, Alain, Vouillamoz, Dominique, Vulliamy, Rachel, Wermuth, Jürg, Werner, Helene, Wiesel, Paul, Wiest, Reiner, Wylie, Tina, Zeitz, Jonas, Zimmermann, Dorothee, Mikocka-Walus, Antonina, Pittet, Valerie, and von Känel, Roland
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- 2016
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9. Fusing LIDAR and Vision for Autonomous Dirt Road Following : Incorporating a Visual Feature into the Tentacles Approach
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Manz, Michael, Himmelsbach, Michael, Luettel, Thorsten, Wuensche, Hans-Joachim, Brauer, W., editor, Dillmann, Rüdiger, editor, Beyerer, Jürgen, editor, Stiller, Christoph, editor, Zöllner, J. Marius, editor, and Gindele, Tobias, editor
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- 2009
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10. The Relevance of Vitamin and Iron Deficiency in Patients with Inflammatory Bowel Diseases in Patients of the Swiss IBD Cohort
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Madanchi, Matiar, Fagagnini, Stefania, Fournier, Nicolas, Biedermann, Luc, Zeitz, Jonas, Battegay, Edouard, Zimmerli, Lukas, Vavricka, Stephan R, Rogler, Gerhard, Scharl, Michael, Anderegg, Claudia, Bauerfeind, Peter, Beglinger, Christoph, Begré, Stefan, Belli, Dominique, Bengoa, José M, Biedermann, Luc, Bigler, Beat, Binek, Janek, Blattmann, Mirjam, Boehm, Stephan, Borovicka, Jan, Braegger, Christian P, Brunner, Nora, Bühr, Patrick, Burnand, Bernard, Burri, Emanuel, Buyse, Sophie, Cremer, Matthias, Criblez, Dominique H, Saussure, Philippe de, Degen, Lukas, Delarive, Joakim, Doerig, Christopher, Dora, Barbara, Dorta, Gian, Egger, Mara, Ehmann, Tobias, El-Wafa, Ali, Engelmann, Matthias, Ezri, Jessica, Felley, Christian, Fliegner, Markus, Fournier, Nicolas, Fraga, Montserrat, Frei, Pascal, Frei, Remus, Fried, Michael, Froehlich, Florian, Funk, Christian, Furlano, Raoul Ivano, Gallot-Lavallée, Suzanne, Geyer, Martin, Girardin, Marc, Golay, Delphine, Grandinetti, Tanja, Gysi, Beat, Haack, Horst, Haarer, Johannes, Helbling, Beat, Hengstler, Peter, Herzog, Denise, Hess, Cyrill, Heyland, Klaas, Hinterleitner, Thomas, Hiroz, Philippe, Hirschi, Claudia, Hruz, Petr, Iwata, Rika, Jost, Res, Juillerat, Pascal, Brondolo, Vera Kessler, Knellwolf, Christina, Knoblauch, Christoph, Köhler, Henrik, Koller, Rebekka, Krieger-Grübel, Claudia, Kullak-Ublick, Gerd, Künzler, Patrizia, Landolt, Markus, Lange, Rupprecht, Lehmann, Frank Serge, Macpherson, Andrew, Maerten, Philippe, Maillard, Michel H, Manser, Christine, Manz, Michael, Marbet, Urs, Marx, George, Matter, Christoph, McLin, Valérie, Meier, Rémy, Mendanova, Martina, Meyenberger, Christa, Michetti, Pierre, Misselwitz, Benjamin, Moradpour, Darius, Morell, Bernhard, Mosler, Patrick, Mottet, Christian, Müller, Christoph, Müller, Pascal, Müllhaupt, Beat, Münger-Beyeler, Claudia, Musso, Leilla, Nagy, Andreas, Neagu, Michaela, Nichita, Cristina, Niess, Jan, Noël, Natacha, Nydegger, Andreas, Obialo, Nicole, Oneta, Carl, Oropesa, Cassandra, Peter, Ueli, Peternac, Daniel, Petit, Laetitia Marie, Piccoli-Gfeller, Franziska, Pilz, Julia Beatrice, Pittet, Valérie, Raschle, Nadia, Rentsch, Ronald, Restellini, Sophie, Richterich, Jean-Pierre, Rihs, Sylvia, Ritz, Marc Alain, Roduit, Jocelyn, Rogler, Daniela, Rogler, Gerhard, Rossel, Jean-Benoît, Sagmeister, Markus, Saner, Gaby, Sauter, Bernhard, Sawatzki, Mikael, Schäppi, Michela, Scharl, Michael, Schelling, Martin, Schibli, Susanne, Schlauri, Hugo, Uebelhart, Sybille Schmid, Schnegg, Jean-François, Schoepfer, Alain, Seibold, Frank, Seirafi, Mariam, Semadeni, Gian-Marco, Semela, David, Senning, Arne, Sidler, Marc, Sokollik, Christiane, Spalinger, Johannes, Spangenberger, Holger, Stadler, Philippe, Steuerwald, Michael, Straumann, Alex, Straumann-Funk, Bigna, Sulz, Michael, Thorens, Joël, Tiedemann, Sarah, Tutuian, Radu, Vavricka, Stephan, Viani, Francesco, Vögtlin, Jürg, Känel, Roland Von, Vonlaufen, Alain, Vouillamoz, Dominique, Vulliamy, Rachel, Wermuth, Jürg, Werner, Helene, Wiesel, Paul, Wiest, Reiner, Wylie, Tina, Zeitz, Jonas, and Zimmermann, Dorothee
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- 2018
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11. Economic Literacy and Inflation Expectations: Evidence from a Laboratory Experiment
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BURKE, MARY A. and MANZ, MICHAEL
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- 2014
12. Genetic polymorphisms associated with smoking behaviour predict the risk of surgery in patients with Crohnʼs disease
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Lang, B. M., Biedermann, L., van Haaften, W. T., de Vallière, C., Schuurmans, M., Begré, S., Zeitz, J., Scharl, M., Turina, M., Greuter, T., Schreiner, P., Heinrich, H., Kuntzen, T., Vavricka, S. R., Rogler, G., Beerenwinkel, N., Misselwitz, B., Anderegg, Claudia, Bauerfeind, Peter, Beglinger, Christoph, Begré, Stefan, Bengoa, José M., Biedermann, Luc, Bigler, Beat, Binek, Janek, Blattmann, Mirjam, Boehm, Stephan, Borovicka, Jan, Braegger, Christian P., Brunner, Nora, Bühr, Patrick, Burnand, Bernard, Burri, Emanuel, Buyse, Sophie, Cremer, Matthias, Criblez, Dominique H., de Saussure, Philippe, Degen, Lukas, Delarive, Joakim, Doerig, Christopher, Dora, Barbara, Dorta, Gian, Egger, Mara, Ehmann, Tobias, El‐Wafa, Ali, Engelmann, Matthias, Ezri, a, Felley, Christian, Fliegner, Markus, Fournier, Nicolas, Fraga, Montserrat, Frei, Pascal, Frei, Remus, Fried, Michael, Froehlich, Florian, Funk, Christian, Furlano, Raoul Ivano, Gallot‐Lavallée, Suzanne, Geyer, Martin, Girardin, Marc, Golay, Delphine, Grandinetti, Tanja, Gysi, Beat, Haack, Horst, Haarer, Johannes, Helbling, Beat, Hengstler, Peter, Herzog, Denise, Hess, Cyrill, Heyland, Klaas, Hinterleitner, Thomas, Hiroz, Philippe, Hirschi, Claudia, Hruz, Petr, Iwata, Rika, Jost, Res, Juillerat, Pascal, Kessler Brondolo, Vera, Knellwolf, Christina, Knoblauch, Christoph, Köhler, Henrik, Koller, Rebekka, Krieger‐Grübel, Claudia, Kullak‐Ublick, Gerd, Künzler, Patrizia, Landolt, Markus, Lange, Rupprecht, Lehmann, Frank Serge, Macpherson, Andrew, Maerten, Philippe, Maillard, Michel H., Manser, Christine, Manz, Michael, Marbet, Urs, Marx, George, Matter, Christoph, McLin, Valérie, Meier, Rémy, Mendanova, Martina, Meyenberger, Christa, Michetti, Pierre, Misselwitz, Benjamin, Moradpour, Darius, Morell, Bernhard, Mosler, Patrick, Mottet, Christian, Müller, Christoph, Müller, Pascal, Müllhaupt, Beat, Münger‐Beyeler, Claudia, Musso, Leilla, Nagy, Andreas, Neagu, Michaela, Nichita, Cristina, Niess, Jan, Noël, Natacha, Nydegger, Andreas, Obialo, Nicole, Oneta, Carl, Oropesa, Cassandra, Peter, Ueli, Peternac, Daniel, Petit, Laetitia Marie, Piccoli‐Gfeller, Franziska, Pilz, Julia Beatrice, Pittet, Valérie, Raschle, Nadia, Rentsch, Ronald, Restellini, Sophie, Richterich, Jean‐Pierre, Rihs, Sylvia, Ritz, Marc Alain, Roduit, Jocelyn, Rogler, Daniela, Rogler, Gerhard, Rossel, Jean‐Benoît, Sagmeister, Markus, Saner, Gaby, Sauter, Bernhard, Sawatzki, Mikael, Schäppi, Michela, Scharl, Michael, Schelling, Martin, Schibli, Susanne, Schlauri, Hugo, Uebelhart, Sybille Schmid, Schnegg, Jean‐François, Schoepfer, Alain, Seibold, Frank, Seirafi, Mariam, Semadeni, Gian‐Marco, Semela, David, Senning, Arne, Sidler, Marc, Sokollik, Christiane, Spalinger, Johannes, Spangenberger, Holger, Stadler, Philippe, Steuerwald, Michael, Straumann, Alex, Straumann‐Funk, Bigna, Sulz, Michael, Thorens, Joël, Tiedemann, Sarah, Tutuian, Radu, Vavricka, Stephan, Viani, Francesco, Vögtlin, Jürg, Von Känel, Roland, Vonlaufen, Alain, Vouillamoz, Dominique, Vulliamy, Rachel, Wermuth, Jürg, Werner, Helene, Wiesel, Paul, Wiest, Reiner, Wylie, Tina, Zeitz, Jonas, and Zimmermann, Dorothee
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- 2018
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13. Was sich hinter einer "schwarzen Hämorrhoide" verbergen kann
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Becker, Pauline Maja, primary, Manz, Michael, additional, and Steinemann, Daniel, additional
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- 2022
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14. Hyposalivation and dietary nutrient intake among community-based older Japanese
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Iwasaki, Masanori, Yoshihara, Akihiro, Ito, Kayoko, Sato, Misuzu, Minagawa, Kumiko, Muramatsu, Kanako, Watanabe, Reiko, Manz, Michael C., Ansai, Toshihiro, and Miyazaki, Hideo
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- 2016
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15. Information-based contagion and the implications for financial fragility
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Manz, Michael
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- 2010
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16. Impact of the early use of immunomodulators or TNF antagonists on bowel damage and surgery in Crohnʼs disease
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Safroneeva, E., Vavricka, S. R., Fournier, N., Pittet, V., Peyrin-Biroulet, L., Straumann, A., Rogler, G., Schoepfer, A. M., Bauerfeind, Peter, Beglinger, Christoph, Begré, Stefan, Bengoa, José, Binek, Janek, Boller, Daniel, Borovicka, Jan, Braegger, Christian, Burnand, Bernard, Camara, Rafael, Criblez, Dominique, de Saussure, Philippe, Degen, Lukas, Delarive, Joakim, Ehmann, Tobias, Engelmann, Matthias, Wafa, Ali El, Felley, Christian, Frei, Alain, Frei, Remus, Fried, Michael, Friedt, Michael, Froehlich, Florian, Gallot-Lavallée, Suzanne, Gerlach, Tilman, Geyer, Martin, Girardin, Marc, Goetze, Oliver, Haack, Horst, Hediger, Serge, Hengstler, Peter, Heyland, Klaas, Janiak, Patrick, Juillerat, Pascal, Brondolo, Vera Kessler, Knoblauch, Christoph, Kullak-Ublick, Gerd A., Maillard, Michel, Manz, Michael, Marbet, Urs, Meier, Rémy, Meyenberger, Christa, Michetti, Pierre, Mottet, Christian, Müller, Christoph, Müllhaupt, Beat, Nicolet, Thierry, Nydegger, Andreas, Pache, Isabelle, Piccoli, Franziska, Pilz, Julia, Rentsch, Ronald, Rey, Jean-Pierre, Rihs, Silvia, Rogler, Daniela, Sagmeister, Markus, Sauter, Bernhard, Schaub, Niklaus, Schibli, Susanne, Seibold, Frank, Spalinger, Johannes, Stadler, Philippe, Steuerwald, Michael, Sul, Michael, Tempia-Caliera, Michela, Thorens, Joël, Vader, John-Paul, Vögtlin, Jürg, Von Känel, Roland, Wachter, Gert, Wermuth, Jürg, and Wiesel, Paul
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- 2015
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17. Systematic analysis of factors associated with progression and regression of ulcerative colitis in 918 patients
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Safroneeva, E., Vavricka, S., Fournier, N., Seibold, F., Mottet, C., Nydegger, A., Ezri, J., Straumann, A., Rogler, G., Schoepfer, A. M., Bauerfeind, Peter, Beglinger, Christoph, Begré, Stefan, Bengoa, José, Binek, Janek, Boller, Daniel, Borovicka, Jan, Braegger, Christian, Burnand, Bernard, Camara, Rafael, Criblez, Dominique, de Saussure, Philippe, Degen, Lukas, Delarive, Joakim, Ehmann, Tobias, Engelmann, Matthias, Wafa, Ali El, Felley, Christian, Frei, Alain, Frei, Pascal, Frei, Remus, Fried, Michael, Froehlich, Florian, Gallot-Lavallée, Suzanne, Gerlach, Tilman, Geyer, Martin, Girardin, Marc, Goetze, Oliver, Haack, Horst, Hediger, Serge, Hengstler, Peter, Heyland, Klaas, Janiak, Patrick, Juillerat, Pascal, Brondolo, Vera Kessler, Knoblauch, Christoph, Kullak-Ublick, Gerd A., Maillard, Michel, Manser, Christine, Marbet, Urs, Manz, Michael, Meier, Rémy, Meyenberger, Christa, Michetti, Pierre, Mottet, Christian, Müller, Christoph, Müllhaupt, Beat, Nicolet, Thierry, Nydegger, Andreas, Piccoli, Franziska, Pilz, Julia, Pittet, Valérie, Rentsch, Ronald, Rey, Jean-Pierre, Rogler, Daniela, Rogler, Gerhard, Sagmeister, Markus, Sauter, Bernhard, Schaub, Niklaus, Schibli, Susanne, Schoepfer, Alain M., Seibold, Frank, Spalinger, Johannes, Stadler, Philippe, Steuerwald, Michael, Straumann, Alex, Sulz, Michael, Thorens, Joël, Vader, John-Paul, Vavricka, Stephan R., Vögtlin, Jürg, Von Känel, Roland, Wachter, Gert, Wermuth, Jürg, and Wiesel, Paul
- Published
- 2015
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18. Is there an Appalachian disparity in dental caries in Pennsylvania schoolchildren?
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Polk, Deborah E., Kim, Sunghee, Manz, Michael, and Weyant, Robert J.
- Published
- 2015
- Full Text
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19. Symptoms of Depression and Anxiety Are Independently Associated With Clinical Recurrence of Inflammatory Bowel Disease
- Author
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Mikocka-Walus, Antonina, Pittet, Valerie, Rossel, Jean-Benoît, von Känel, Roland, Anderegg, Claudia, Bauerfeind, Peter, Beglinger, Christoph, Begré, Stefan, Belli, Dominique, Bengoa, José M., Biedermann, Luc, Bigler, Beat, Binek, Janek, Blattmann, Mirjam, Boehm, Stephan, Borovicka, Jan, Braegger, Christian P., Brunner, Nora, Bühr, Patrick, Burnand, Bernard, Burri, Emanuel, Buyse, Sophie, Cremer, Matthias, Criblez, Dominique H., de Saussure, Philippe, Degen, Lukas, Delarive, Joakim, Doerig, Christopher, Dora, Barbara, Dorta, Gian, Egger, Mara, Ehmann, Tobias, El-Wafa, Ali, Engelmann, Matthias, Ezri, Jessica, Felley, Christian, Fliegner, Markus, Fournier, Nicolas, Fraga, Montserrat, Frei, Pascal, Frei, Remus, Fried, Michael, Froehlich, Florian, Funk, Christian, Ivano Furlano, Raoul, Gallot-Lavallée, Suzanne, Geyer, Martin, Girardin, Marc, Golay, Delphine, Grandinetti, Tanja, Gysi, Beat, Haack, Horst, Haarer, Johannes, Helbling, Beat, Hengstler, Peter, Herzog, Denise, Hess, Cyrill, Heyland, Klaas, Hinterleitner, Thomas, Hiroz, Philippe, Hirschi, Claudia, Hruz, Petr, Iwata, Rika, Jost, Res, Juillerat, Pascal, Kessler Brondolo, Vera, Knellwolf, Christina, Knoblauch, Christoph, Köhler, Henrik, Koller, Rebekka, Krieger-Grübel, Claudia, Kullak-Ublick, Gerd, Künzler, Patrizia, Landolt, Markus, Lange, Rupprecht, Serge Lehmann, Frank, Macpherson, Andrew, Maerten, Philippe, Maillard, Michel H., Manser, Christine, Manz, Michael, Marbet, Urs, Marx, George, Matter, Christoph, McLin, Valérie, Meier, Rémy, Mendanova, Martina, Meyenberger, Christa, Michetti, Pierre, Misselwitz, Benjamin, Moradpour, Darius, Morell, Bernhard, Mosler, Patrick, Mottet, Christian, Müller, Christoph, Müller, Pascal, Müllhaupt, Beat, Münger-Beyeler, Claudia, Musso, Leilla, Nagy, Andreas, Neagu, Michaela, Nichita, Cristina, Niess, Jan, Noël, Natacha, Nydegger, Andreas, Obialo, Nicole, Oneta, Carl, Oropesa, Cassandra, Peter, Ueli, Peternac, Daniel, Marie Petit, Laetitia, Piccoli-Gfeller, Franziska, Beatrice Pilz, Julia, Pittet, Valérie, Raschle, Nadia, Rentsch, Ronald, Restellini, Sophie, Richterich, Jean-Pierre, Rihs, Sylvia, Alain Ritz, Marc, Roduit, Jocelyn, Rogler, Daniela, Rogler, Gerhard, Rossel, Jean-Benoît, Sagmeister, Markus, Saner, Gaby, Sauter, Bernhard, Sawatzki, Mikael, Schäppi, Michela, Scharl, Michael, Schelling, Martin, Schibli, Susanne, Schlauri, Hugo, Schmid Uebelhart, Sybille, Schnegg, Jean-François, Schoepfer, Alain, Seibold, Frank, Seirafi, Mariam, Semadeni, Gian-Marco, Semela, David, Senning, Arne, Sidler, Marc, Sokollik, Christiane, Spalinger, Johannes, Spangenberger, Holger, Stadler, Philippe, Steuerwald, Michael, Straumann, Alex, Straumann-Funk, Bigna, Sulz, Michael, Thorens, Joël, Tiedemann, Sarah, Tutuian, Radu, Vavricka, Stephan, Viani, Francesco, Vögtlin, Jürg, Von Känel, Roland, Vonlaufen, Alain, Vouillamoz, Dominique, Vulliamy, Rachel, Wermuth, Jürg, Werner, Helene, Wiesel, Paul, Wiest, Reiner, Wylie, Tina, Zeitz, Jonas, and Zimmermann, Dorothee
- Published
- 2016
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20. Oral health status: relationship to nutrient and food intake among 80-year-old Japanese adults
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Iwasaki, Masanori, Taylor, George W., Manz, Michael C., Yoshihara, Akihiro, Sato, Misuzu, Muramatsu, Kanako, Watanabe, Reiko, and Miyazaki, Hideo
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- 2014
- Full Text
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21. Therapies in Inflammatory Bowel Disease Patients with Extraintestinal Manifestations
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Juillerat, Pascal, Manz, Michael, Sauter, Bernhard, Zeitz, Jonas, Vavricka, Stephan R, Juillerat, Pascal, Manz, Michael, Sauter, Bernhard, Zeitz, Jonas, and Vavricka, Stephan R
- Abstract
Extraintestinal manifestations (EIM) have become an important source of morbidity and disability as well as an identified risk factor for an unfavorably course of disease in inflammatory bowel diseases (IBD). Therefore, efforts have been put into a more global and interdisciplinary management of IBD patients in collaboration with rheumatologists, dermatologists, and ophthalmologists. A real therapeutic success has also been obtained with a more "systemic" IBD treatment associated with the development of monoclonal antibodies against TNF alpha and biological agents derived from the treatment of rheumatological disease (also called biological Disease-Modifying Antirheumatic Drugs). The prevalence of these EIM remains too low to undergo randomized controlled trials with this specific focus and therefore the evidence relies on case series and experts' opinions, which lowers the level of evidence. After a careful review of the most recent literature, this paper aims to update the reader on the latest therapeutic management of IBD patients with EIM.
- Published
- 2020
22. Effects of anti-TNF therapy and immunomodulators on anxiety and depressive symptoms in patients with inflammatory bowel disease: a 5-year analysis
- Author
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Siebenhüner, Alexander R., primary, Rossel, Jean-Benoît, additional, Schreiner, Philipp, additional, Butter, Matthias, additional, Greuter, Thomas, additional, Krupka, Niklas, additional, Jordi, Sebastian B. U., additional, Biedermann, Luc, additional, Rogler, Gerhard, additional, Misselwitz, Benjamin, additional, von Känel, Roland, additional, Abdelrahman, Karim, additional, Ademi, Gentiana, additional, Aepli, Patrick, additional, Thomas, Amman, additional, Anderegg, Claudia, additional, Antonino, Anca-Teodora, additional, Archanioti, Eva, additional, Arrigoni, Eviano, additional, Aslan, Nurullah, additional, Bakker de Jong, Diana, additional, Balsiger, Bruno, additional, Barry, Mamadou-Pathé, additional, Bastürk, Polat, additional, Bauerfeind, Peter, additional, Becocci, Andrea, additional, Bengoa, José M., additional, Binek, Janek, additional, Blattmann, Mirjam, additional, Boehm, Stephan, additional, Boldanova, Tujana, additional, Borovicka, Jan, additional, Braegger, Christian P., additional, Brand, Stephan, additional, Bravo, Francisco, additional, Brügger, Lukas, additional, Brunner, Simon, additional, Bühr, Patrick, additional, Burk, Sabine, additional, Burri, Emanuel, additional, Buyse, Sophie, additional, Cao, Dahlia-Thao, additional, Carstens, Ove, additional, Criblez, Dominique H., additional, D’Angelo, Fabrizia, additional, Saussure, Philippe de, additional, Degen, Lukas, additional, Delarive, Joakim, additional, Doerig, Christopher, additional, Dora, Barbara, additional, Drerup, Susan, additional, Ducrey, Carole, additional, El-Wafa, Ali, additional, Engelmann, Matthias, additional, Erdmann-Voisin, Aude, additional, Felley, Christian, additional, Fliegner, Markus, additional, Fraga, Montserrat, additional, Franc, Yannick, additional, Frei, Pascal, additional, Frei, Remus, additional, Fried, Michael, additional, Froehlich, Florian, additional, Ivano Furlano, Raoul, additional, Garzoni, Luca, additional, Geyer, Martin, additional, Girardin, Marc, additional, Golay, Delphine, additional, Good, Ignaz, additional, Graf Bigler, Ulrike, additional, Godat, Sébastien, additional, Gysi, Beat, additional, Haarer, Johannes, additional, Halama, Marcel, additional, Haldemann, Janine, additional, Heer, Pius, additional, Heimgartner, Benjamin, additional, Helbling, Beat, additional, Hengstler, Peter, additional, Herzog, Denise, additional, Hess, Cyrill, additional, Hessler, Roxane, additional, Heyland, Klaas, additional, Hinterleitner, Thomas, additional, Hirschi, Claudia, additional, Hruz, Petr, additional, Juillerat, Pascal, additional, Kapoglou, Ioannis, additional, Kayser, Stephan, additional, Keller, Céline, additional, Khalid-de Bakker, Carolina, additional, Knellwolf, Christina, additional, Knoblauch, Christoph, additional, Köhler, Henrik, additional, Koller, Rebekka, additional, Krieger, Claudia, additional, Künzler, Patrizia, additional, Kusche, Rachel, additional, Serge Lehmann, Frank, additional, Macpherson, Andrew, additional, Maillard, Michel H., additional, Manz, Michael, additional, Martinho, Maude, additional, Meier, Rémy, additional, Meyenberger, Christa, additional, Meyer, Pamela, additional, Michetti, Pierre, additional, Morell, Bernhard, additional, Mosler, Patrick, additional, Moschouri, Eleni, additional, Mottet, Christian, additional, Müller, Christoph, additional, Müllhaupt, Beat, additional, Musso, Leilla, additional, Neagu, Michaela, additional, Nichita, Cristina, additional, Niess, Jan, additional, Nydegger, Andreas, additional, Obialo, Nicole, additional, Oropesa, Cassandra, additional, Peter, Ulrich, additional, Peternac, Daniel, additional, Marie Petit, Laetitia, additional, Pittet, Valérie, additional, Pohl, Daniel, additional, Porzner, Marc, additional, Preissler, Claudia, additional, Raschle, Nadia, additional, Rentsch, Ronald, additional, Restellini, Sophie, additional, Richterich, Jean-Pierre, additional, Riedmüller, Sandra, additional, Risti, Branislav, additional, Alain Ritz, Marc, additional, Röhrich, Nina, additional, Roth, René, additional, Rueger, Vanessa, additional, Sagmeister, Markus, additional, Saner, Gaby, additional, Sarraj, Riad, additional, Sauter, Bernhard, additional, Sawatzki, Mikael, additional, Scharl, Michael, additional, Scharl, Sylvie, additional, Schelling, Martin, additional, Schibli, Susanne, additional, Schlauri, Hugo, additional, Schluckebier, Dominique, additional, Schmid, Daniela, additional, Schmid, Sybille, additional, Schnegg, Jean-François, additional, Schoepfer, Alain, additional, Seibold, Frank, additional, Seirafi, Mariam, additional, Semadeni, Gian-Marco, additional, Senning, Arne, additional, Sokollik, Christiane, additional, Sommer, Joachim, additional, Spalinger, Johannes, additional, Spangenberger, Holger, additional, Stadler, Philippe, additional, Staub, Peter, additional, Staudenmann, Dominic, additional, Stenz, Volker, additional, Steuerwald, Michael, additional, Straumann, Alex, additional, Stulz, Andreas, additional, Sulz, Michael, additional, Tempia-Caliera, Michela, additional, Thorens, Joël, additional, Truninger, Kaspar, additional, Tutuian, Radu, additional, Urfer, Patrick, additional, Vavricka, Stephan, additional, Viani, Francesco, additional, Vinzens, Fabrizion, additional, Vögtlin, Jürg, additional, Von Känel, Roland, additional, Vouillamoz, Dominique, additional, Vulliamy, Rachel, additional, Vullièmoz, Marianne, additional, Wiesel, Paul, additional, Wiest, Reiner, additional, Wöhrle, Stefanie, additional, Yilmaz, Bahtiyar, additional, Zamora, Samuel, additional, Zander, Silvan, additional, Zeitz, Jonas, additional, and Zimmermann, Dorothee, additional
- Published
- 2021
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23. Dental visits and access to dental care among Maryland schoolchildren
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Macek, Mark D., Wagner, Mark L., Manz, Michael C., and Marrazo, Ilise D.
- Subjects
Elementary school students -- Health aspects ,Elementary school students -- Research ,Dental care -- Utilization ,Dental care -- Research ,Health - Abstract
A study on Maryland school children in kindergarten to third standard on accessing and utilization of oral health care services is presented.
- Published
- 2005
24. Fusing LIDAR and Vision for Autonomous Dirt Road Following
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Manz, Michael, primary, Himmelsbach, Michael, additional, Luettel, Thorsten, additional, and Wuensche, Hans-Joachim, additional
- Published
- 2009
- Full Text
- View/download PDF
25. Reactivation of hepatitis B virus with mutated hepatitis B surface antigen in a liver transplant recipient receiving a graft from an antibody to hepatitis B surface antigen– and antibody to hepatitis B core antigen–positive donor
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Blaich, Annette, Manz, Michael, Dumoulin, Alexis, Schüttler, Christian G., Hirsch, Hans H., Gerlich, Wolfram H., and Frei, Reno
- Published
- 2012
- Full Text
- View/download PDF
26. High Extraction Efficiency for POPs in Real Contaminated Soil Samples Using Accelerated Solvent Extraction
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Hubert, Andreas, Wenzel, Klaus-Dieter, Manz, Michael, Weissflog, Ludwig, Engewald, Werner, and Schuurmann, Gerrit
- Subjects
Chemistry, Analytic -- Research ,Pollutants -- Research ,Chlorobenzene -- Research ,Solvents -- Research ,Chemistry - Abstract
Systematic investigations were performed to study the dependence of the extraction efficiency of persistent organic pollutants (POPs), including chlorobenzenes, HCH isomers, DDX, PCB congeners, and PAHs, on the accelerated solvent extraction (ASE) operating variables solvent and temperature. Mixed soil samples from two locations with considerable differences in soil properties and contamination in the Leipzig-Halle region (Germany) were used. The objective was to optimize ASE for the extraction of POPs from real soil samples and to improve on the results achieved with Soxhlet extraction (SOX). Solvents with differing polarities were tested. Quadruple and triple determinations were performed on the two soils, respectively, between 20 and 180 degrees C in 20 degrees C steps. All the results were compared with those obtained by SOX, as well as, in some cases during preliminary studies, by ultrasonic extraction (USE). In ASE, the optimum conditions proved to be two extraction steps at 80 and 140 degrees C (average RSD 10.7%) with three static cycles (extraction time 35 rain) using toluene as solvent and at a pressure of 15 MPa. Owing to the superior analyte/ matrix separation by ASE, in many cases for real soil samples analytical values better by up to 1 order of magnitude or even more were obtained compared to SOX results.
- Published
- 2000
27. Position statement on the use of biosimilars in inflammatory bowel disease
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Burri, Emanuel, primary, Juillerat, Pascal, additional, Maillard, Michel H., additional, Manz, Michael, additional, Michetti, Pierre, additional, Mottet, Christian, additional, Rogler, Gerhard, additional, Zahnd, Nadine, additional, and Vavricka, Stephan, additional
- Published
- 2019
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- View/download PDF
28. Prevalence of Gingival Overgrowth in Renal Transplant Recipients on Sirolimus Immunosuppressive Therapy is not Clearly Established
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Fisher, Monica A., McCarthy, Ellen T., and Manz, Michael C.
- Published
- 2010
29. Oral healthcare access and adequacy in alternative long-term care facilities
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Smith, Barbara J., Ghezzi, Elisa M., Manz, Michael C., and Markova, Christiana P.
- Published
- 2010
- Full Text
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30. Socioeconomic factors in adolescentsʼ oral health: are they mediated by oral hygiene behaviors or preventive interventions?
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Polk, Deborah E., Weyant, Robert J., and Manz, Michael C.
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- 2010
- Full Text
- View/download PDF
31. Chronic Diarrhea, Weight Loss, and Refractory Epilepsy Three Years After Percutaneous Endoscopic Gastrostomy
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Piccoli–Gfeller, Franziska, Beglinger, Christoph, and Manz, Michael
- Published
- 2009
- Full Text
- View/download PDF
32. Trichuris trichiura (Whipworm)
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Vavricka, Stephan R., Manz, Michael, and Burri, Emanuel
- Published
- 2009
- Full Text
- View/download PDF
33. From Hyperkalemia to Ischemic Colitis: A Resinous Way
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Tapia, Coya, Schneider, Theresa, and Manz, Michael
- Published
- 2009
- Full Text
- View/download PDF
34. Accelerated solvent extraction of semivolatile organic compounds from biomonitoring samples of pine needles and mosses
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Wenzel, Klaus-Dieter, Hubert, Andreas, Manz, Michael, Weissflog, Ludwig, Engewald, Werner, and Schuurmann, Gerrit
- Subjects
Biological monitoring -- Methods ,Moss -- Environmental aspects ,Pine -- Environmental aspects ,Volatile organic compounds -- Analysis ,Chemistry - Abstract
Accelerated solvent extraction (ASE) was used for the simultaneous extraction of semivolatile organic compounds (SOCs) including chlorobenzenes (1,2,3,4-tetra-, penta-, hexachlorobenzene), HCH isomers ([alpha]-,[Beta]-, [Gamma], [Delta]-, [Epsilon]-HCH), DDX (p,p[prime]-DDT, -DDE, -DDD), PCB congeners (28, 52, 101, 138, 153, 180), and PAHs (phenanthrene, anthracene, fluoranthene, pyrene, benzo[a]pyrene) from mosses (Pleurozium sehreberi) growing in regional locations (central Germany) and pine needles (Pinus sylvestris L.) from southern Russia (near the Caspian Sea). The results were compared with those obtained by ultrasonic extraction (USE). Using mixed moss samples (thorough cleanup, only minor interference during GC/MSD analysis) from one location mainly served to optimize two parameters, extraction solvent and temperature. The most favorable extraction conditions proved to be n-hexane as the extraction solvent, two temperature stages of 40 and 120 [degrees] C, a pressure of 15 MPa, and three static cycles in each case. These conditions were then applied to the extraction of SOCs from the wax and the inner pine needle fraction, which beforehand had undergone extractive separation with dichloromethane. ASE was found to be especially advantageous in the case of higher multiple exposures to pollutants and the resultant complicated matrixes (oleiferous extracts, pollutant/matrix conjugates). Owing to the much better separation of analyte/matrix, in many cases increases of 1-2 orders of magnitude were obtained in the analytical values of the contaminated sample materials compared to those obtained with USE.
- Published
- 1998
35. An Atypical Approach to Appendicitis
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Manz, Michael, Peter, Shajan, and Beglinger, Christoph
- Published
- 2008
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36. Factors associated with parentsʼ and adolescentsʼ perceptions of oral health and need for dental treatment
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Weyant, Robert J., Manz, Michael, Corby, Patricia, Rustveld, Luis, and Close, John
- Published
- 2007
37. Position statement on the use of biosimilars in inflammatory bowel disease
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Burri, Emanuel, Juillerat, Pascal; https://orcid.org/0000-0002-0947-5235, Maillard, Michel H, Manz, Michael, Michetti, Pierre; https://orcid.org/0000-0003-4982-7327, Mottet, Christian, Rogler, Gerhard; https://orcid.org/0000-0002-1733-9188, Zahnd, Nadine, Vavricka, Stephan, Burri, Emanuel, Juillerat, Pascal; https://orcid.org/0000-0002-0947-5235, Maillard, Michel H, Manz, Michael, Michetti, Pierre; https://orcid.org/0000-0003-4982-7327, Mottet, Christian, Rogler, Gerhard; https://orcid.org/0000-0002-1733-9188, Zahnd, Nadine, and Vavricka, Stephan
- Abstract
Biologics are effective and have a good safety profile in the treatment of inflammatory bowel disease. Biosimilars have recently become available as treatment option. They are biological agents that are highly similar to the original biologic compound in their structure, biological activity, efficacy and safety. This position paper summarises current knowledge on biosimilars and presents its statements on regulatory issues and clinical situation in order to provide clinicians adequate information for them to reach informed and appropriate shared decision-making with their patients.
- Published
- 2019
38. Value of fecal calprotectin in the evaluation of patients with abdominal discomfort: an observational study
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Manz Michael, Burri Emanuel, Rothen Claude, Tchanguizi Nuschin, Niederberger Christian, Rossi Livio, Beglinger Christoph, and Lehmann Frank
- Subjects
Gastroenterology ,Endoscopy ,Diagnosis ,Biomarker ,Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Abstract Background The evaluation of patients with abdominal discomfort is challenging and patient selection for endoscopy based on symptoms is not reliable. We evaluated the diagnostic value of fecal calprotectin in patients with abdominal discomfort. Methods In an observational study, 575 consecutive patients with abdominal discomfort referred for endoscopy to the Department of Gastroenterology & Hepatology at the University Hospital Basel in Switzerland, were enrolled in the study. Calprotectin was measured in stool samples collected within 24 hours before the investigation using an enzyme-linked immunosorbent assay. The presence of a clinically significant finding in the gastrointestinal tract was the primary endpoint of the study. Final diagnoses were adjudicated blinded to calprotectin values. Results Median calprotectin levels were higher in patients with significant findings (N = 212, median 97 μg/g, IQR 43-185) than in patients without (N = 326, 10 μg/g, IQR 10-23, P < 0.001). The area under the receiver operating characteristics curve (AUC) to identify a significant finding was 0.877 (95% CI, 0.85-0.90). Using 50 μg/g as cut off yielded a sensitivity of 73% and a specificity of 93% with good positive and negative likelihood ratios (10.8 and 0.29, respectively). Fecal calprotectin was useful as a diagnostic parameter both for findings in the upper intestinal tract (AUC 0.730, 0.66-0.79) and for the colon (AUC 0.912, 0.88-0.94) with higher diagnostic precision for the latter (P < 0.001). In patients > 50 years, the diagnostic precision remained unchanged (AUC 0.889 vs. 0.832, P = 0.165). Conclusion In patients with abdominal discomfort, fecal calprotectin is a useful non-invasive marker to identify clinically significant findings of the gastrointestinal tract, irrespective of age.
- Published
- 2012
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39. Differences in Outcomes Reported by Patients With Inflammatory Bowel Diseases vs Their Health Care Professionals
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Pittet, Valérie E.H., primary, Maillard, Michel H., additional, Simonson, Thomas, additional, Fournier, Nicolas, additional, Rogler, Gerhard, additional, Michetti, Pierre, additional, Anderegg, Claudia, additional, Bauerfeind, Peter, additional, Beglinger, Christoph, additional, Begré, Stefan, additional, Belli, Dominique, additional, Bengoa, José M., additional, Biedermann, Luc, additional, Bigler, Beat, additional, Binek, Janek, additional, Blattmann, Mirjam, additional, Boehm, Stephan, additional, Borovicka, Jan, additional, Braegger, Christian P., additional, Brunner, Nora, additional, Bühr, Patrick, additional, Burnand, Bernard, additional, Burri, Emanuel, additional, Buyse, Sophie, additional, Cremer, Matthias, additional, Criblez, Dominique H., additional, de Saussure, Philippe, additional, Degen, Lukas, additional, Delarive, Joakim, additional, Doerig, Christopher, additional, Dora, Barbara, additional, Dorta, Gian, additional, Egger, Mara, additional, Ehmann, Tobias, additional, El-Wafa, Ali, additional, Engelmann, Matthias, additional, Ezri, Jessica, additional, Felley, Christian, additional, Fliegner, Markus, additional, Fraga, Montserrat, additional, Frei, Pascal, additional, Frei, Remus, additional, Fried, Michael, additional, Froehlich, Florian, additional, Funk, Christian, additional, Furlano, Raoul Ivano, additional, Gallot-Lavallée, Suzanne, additional, Geyer, Martin, additional, Girardin, Marc, additional, Golay, Delphine, additional, Grandinetti, Tanja, additional, Gysi, Beat, additional, Haack, Horst, additional, Haarer, Johannes, additional, Helbling, Beat, additional, Hengstler, Peter, additional, Herzog, Denise, additional, Hess, Cyrill, additional, Heyland, Klaas, additional, Hinterleitner, Thomas, additional, Hiroz, Philippe, additional, Hirschi, Claudia, additional, Hruz, Petr, additional, Iwata, Rika, additional, Jost, Res, additional, Juillerat, Pascal, additional, Keller, Céline, additional, Knellwolf, Christina, additional, Knoblauch, Christoph, additional, Köhler, Henrik, additional, Koller, Rebekka, additional, Krieger-Grübel, Claudia, additional, Kullak-Ublick, Gerd, additional, Künzler, Patrizia, additional, Landolt, Markus, additional, Lange, Rupprecht, additional, Lehmann, Frank Serge, additional, Macpherson, Andrew, additional, Maerten, Philippe, additional, Manser, Christine, additional, Manz, Michael, additional, Marbet, Urs, additional, Marx, George, additional, Matter, Christoph, additional, Meier, Rémy, additional, Mendanova, Martina, additional, Misselwitz, Benjamin, additional, Morell, Bernhard, additional, Mosler, Patrick, additional, Mottet, Christian, additional, Müller, Christoph, additional, Müller, Pascal, additional, Müllhaupt, Beat, additional, Münger-Beyeler, Claudia, additional, Musso, Leilla, additional, Nagy, Andreas, additional, Neagu, Michaela, additional, Nichita, Cristina, additional, Niess, Jan, additional, Nydegger, Andreas, additional, Obialo, Nicole, additional, Oneta, Carl, additional, Oropesa, Cassandra, additional, Peter, Ueli, additional, Peternac, Daniel, additional, Petit, Laetitia Marie, additional, Piccoli-Gfeller, Franziska, additional, Pilz, Julia Beatrice, additional, Pittet, Valérie, additional, Raschle, Nadia, additional, Rentsch, Ronald, additional, Restellini, Sophie, additional, Richterich, Jean-Pierre, additional, Rihs, Sylvia, additional, Ritz, Marc Alain, additional, Roduit, Jocelyn, additional, Rogler, Daniela, additional, Rossel, Jean-Benoît, additional, Rueger, Vanessa, additional, Saner, Gaby, additional, Sauter, Bernhard, additional, Sawatzki, Mikael, additional, Schäppi, Michela, additional, Scharl, Michael, additional, Scharl, Sylvie, additional, Schelling, Martin, additional, Schibli, Susanne, additional, Schlauri, Hugo, additional, Uebelhart, Sybille Schmid, additional, Schnegg, Jean-François, additional, Schoepfer, Alain, additional, Seibold, Frank, additional, Seirafi, Mariam, additional, Semadeni, Gian-Marco, additional, Semela, David, additional, Senning, Arne, additional, Sidler, Marc, additional, Sokollik, Christiane, additional, Spalinger, Johannes, additional, Spangenberger, Holger, additional, Stadler, Philippe, additional, Steuerwald, Michael, additional, Straumann, Alex, additional, Straumann-Funk, Bigna, additional, Sulz, Michael, additional, Suter, Alexandra, additional, Thorens, Joël, additional, Tiedemann, Sarah, additional, Tutuian, Radu, additional, Vavricka, Stephan, additional, Viani, Francesco, additional, Vögtlin, Jürg, additional, Von Känel, Roland, additional, Vonlaufen, Alain, additional, Vouillamoz, Dominique, additional, Vulliamy, Rachel, additional, Wermuth, Jürg, additional, Werner, Helene, additional, Wiesel, Paul, additional, Wiest, Reiner, additional, Wylie, Tina, additional, Zeitz, Jonas, additional, and Zimmermann, Dorothee, additional
- Published
- 2019
- Full Text
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40. Uveitis manifestations in patients of the Swiss Inflammatory Bowel Disease Cohort Study
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Biedermann, Luc, primary, Renz, Laura, additional, Fournier, Nicolas, additional, Rossel, Jean-Benoît, additional, Butter, Matthias, additional, Bluemel, Sena, additional, Vavricka, Stephan R., additional, Rogler, Gerhard, additional, Scharl, Michael, additional, Anderegg, Claudia, additional, Bauerfeind, Peter, additional, Beglinger, Christoph, additional, Begré, Stefan, additional, Belli, Dominique, additional, Bengoa, José M., additional, Biedermann, Luc, additional, Bigler, Beat, additional, Binek, Janek, additional, Blattmann, Mirjam, additional, Boehm, Stephan, additional, Borovicka, Jan, additional, Braegger, Christian P., additional, Brunner, Nora, additional, Bühr, Patrick, additional, Burnand, Bernard, additional, Burri, Emanuel, additional, Buyse, Sophie, additional, Cremer, Matthias, additional, Criblez, Dominique H., additional, Saussure, Philippe de, additional, Degen, Lukas, additional, Delarive, Joakim, additional, Doerig, Christopher, additional, Dora, Barbara, additional, Dorta, Gian, additional, Egger, Mara, additional, Ehmann, Tobias, additional, El-Wafa, Ali, additional, Engelmann, Matthias, additional, Ezri, Jessica, additional, Felley, Christian, additional, Fliegner, Markus, additional, Fraga, Montserrat, additional, Frei, Pascal, additional, Frei, Remus, additional, Fried, Michael, additional, Froehlich, Florian, additional, Funk, Christian, additional, Ivano Furlano, Raoul, additional, Gallot-Lavallée, Suzanne, additional, Geyer, Martin, additional, Girardin, Marc, additional, Golay, Delphine, additional, Grandinetti, Tanja, additional, Gysi, Beat, additional, Haack, Horst, additional, Haarer, Johannes, additional, Helbling, Beat, additional, Hengstler, Peter, additional, Herzog, Denise, additional, Hess, Cyrill, additional, Heyland, Klaas, additional, Hinterleitner, Thomas, additional, Hiroz, Philippe, additional, Hirschi, Claudia, additional, Hruz, Petr, additional, Iwata, Rika, additional, Jost, Res, additional, Juillerat, Pascal, additional, Kessler Brondolo, Vera, additional, Knellwolf, Christina, additional, Knoblauch, Christoph, additional, Köhler, Henrik, additional, Koller, Rebekka, additional, Krieger-Grübel, Claudia, additional, Kullak-Ublick, Gerd, additional, Künzler, Patrizia, additional, Landolt, Markus, additional, Lange, Rupprecht, additional, Serge Lehmann, Frank, additional, Macpherson, Andrew, additional, Maerten, Philippe, additional, Maillard, Michel H., additional, Manser, Christine, additional, Manz, Michael, additional, Marbet, Urs, additional, Marx, George, additional, Matter, Christoph, additional, McLin, Valérie, additional, Meier, Rémy, additional, Mendanova, Martina, additional, Meyenberger, Christa, additional, Michetti, Pierre, additional, Misselwitz, Benjamin, additional, Moradpour, Darius, additional, Morell, Bernhard, additional, Mosler, Patrick, additional, Mottet, Christian, additional, Müller, Christoph, additional, Müller, Pascal, additional, Müllhaupt, Beat, additional, Münger-Beyeler, Claudia, additional, Musso, Leilla, additional, Nagy, Andreas, additional, Neagu, Michaela, additional, Nichita, Cristina, additional, Niess, Jan, additional, Noël, Natacha, additional, Nydegger, Andreas, additional, Obialo, Nicole, additional, Oneta, Carl, additional, Oropesa, Cassandra, additional, Peter, Ueli, additional, Peternac, Daniel, additional, Marie Petit, Laetitia, additional, Piccoli-Gfeller, Franziska, additional, Beatrice Pilz, Julia, additional, Pittet, Valérie, additional, Raschle, Nadia, additional, Rentsch, Ronald, additional, Restellini, Sophie, additional, Richterich, Jean-Pierre, additional, Rihs, Sylvia, additional, Alain Ritz, Marc, additional, Roduit, Jocelyn, additional, Rogler, Daniela, additional, Sagmeister, Markus, additional, Saner, Gaby, additional, Sauter, Bernhard, additional, Sawatzki, Mikael, additional, Schäppi, Michela, additional, Schelling, Martin, additional, Schibli, Susanne, additional, Schlauri, Hugo, additional, Schmid Uebelhart, Sybille, additional, Schnegg, Jean-François, additional, Schoepfer, Alain, additional, Seibold, Frank, additional, Seirafi, Mariam, additional, Semadeni, Gian-Marco, additional, Semela, David, additional, Senning, Arne, additional, Sidler, Marc, additional, Sokollik, Christiane, additional, Spalinger, Johannes, additional, Spangenberger, Holger, additional, Stadler, Philippe, additional, Steuerwald, Michael, additional, Straumann, Alex, additional, Straumann-Funk, Bigna, additional, Sulz, Michael, additional, Thorens, Joël, additional, Tiedemann, Sarah, additional, Tutuian, Radu, additional, Vavricka, Stephan, additional, Viani, Francesco, additional, Vögtlin, Jürg, additional, Von Känel, Roland, additional, Vonlaufen, Alain, additional, Vouillamoz, Dominique, additional, Vulliamy, Rachel, additional, Wermuth, Jürg, additional, Werner, Helene, additional, Wiesel, Paul, additional, Wiest, Reiner, additional, Wylie, Tina, additional, Zeitz, Jonas, additional, and Zimmermann, Dorothee, additional
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- 2019
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41. Deregulation of transcription factors controlling intestinal epithelial cell differentiation; a predisposing factor for reduced enteroendocrine cell number in morbidly obese individuals
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Wölnerhanssen, Bettina K., Moran, Andrew W., Burdyga, Galina, Meyer-Gerspach, Anne Christin, Peterli, Ralph, Manz, Michael, Thumshirn, Miriam, Daly, Kristian, Beglinger, Christoph, and Shirazi-Beechey, Soraya P.
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Adult ,Male ,Duodenum ,Science ,Enteroendocrine Cells ,digestive, oral, and skin physiology ,Gene Expression ,Cell Differentiation ,Epithelial Cells ,digestive system ,Immunohistochemistry ,Article ,Body Mass Index ,Obesity, Morbid ,Gastrointestinal Hormones ,Gene Expression Regulation ,Medicine ,Chromogranin A ,Humans ,Female ,Intestinal Mucosa ,Biomarkers ,Transcription Factors - Abstract
Morbidly obese patients exhibit impaired secretion of gut hormones that may contribute to the development of obesity. After bariatric surgery there is a dramatic increase in gut hormone release. In this study, gastric and duodenal tissues were endoscopically collected from lean, and morbidly obese subjects before and 3 months after laparoscopic sleeve gastrectomy (LSG). Tissue morphology, abundance of chromogranin A, gut hormones, α-defensin, mucin 2, Na+/glucose co-transporter 1 (SGLT1) and transcription factors, Hes1, HATH1, NeuroD1, and Ngn3, were determined. In obese patients, the total number of enteroendocrine cells (EEC) and EECs containing gut hormones were significantly reduced in the stomach and duodenum, compared to lean, and returned to normality post-LSG. No changes in villus height/crypt depth were observed. A significant increase in mucin 2 and SGLT1 expression was detected in the obese duodenum. Expression levels of transcription factors required for differentiation of absorptive and secretory cell lineages were altered. We propose that in obesity, there is deregulation in differentiation of intestinal epithelial cell lineages that may influence the levels of released gut hormones. Post-LSG cellular differentiation profile is restored. An understanding of molecular mechanisms controlling epithelial cell differentiation in the obese intestine assists in the development of non-invasive therapeutic strategies.
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- 2017
42. Treatment Algorithm for Mild and Moderate-to-Severe Ulcerative Colitis: An Update.
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Burri, Emanuel, Maillard, Michel H., Schoepfer, Alain M., Seibold, Frank, Van Assche, Gert, Rivière, Pauline, Laharie, David, and Manz, Michael
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ULCERATIVE colitis ,ALGORITHMS ,INDIVIDUALIZED medicine ,SMALL molecules ,MEDICAL protocols - Abstract
Background: Patient care in ulcerative colitis (UC) remains challenging despite an array of established treatment options and emerging new therapies. The management of UC therapy should be guided by the endoscopic extent of inflammation, disease severity, and prognostic factors of poor outcome. Complete remission, defined as durable symptomatic and endoscopic remission without corticosteroid therapy, is the desired treatment goal. Summary: This review focuses on treatment recommendations for different clinical scenarios in moderate-to-severe UC: Active UC of any extent not responding to aminosalicylates, steroid-dependent UC, steroid-refractory UC, immunomodulator-refractory UC, and acute severe UC. Comprehensive treatment algorithms for daily clinical practice were developed based on published guidelines and current literature. Key Messages: While current treatment options including a number of biologicals and small molecules have evolved UC treatment to achieve sustained remission in a majority of patients, upcoming treatment options with different molecular pathways and different modes of actions will further increase the need for personalized medicine. [ABSTRACT FROM AUTHOR]
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- 2020
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43. Akute Pankreatitis
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Winkler, Wulf Daniel, primary, Manz, Michael, additional, and Sauter, Matthias, additional
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- 2018
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44. Pancréatite aiguë
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Winkler, Wulf Daniel, primary, Manz, Michael, additional, and Sauter, Matthias, additional
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- 2018
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45. Prevalence of past-year dental visit among US adults, 1999–2010: comparison of trends and estimates between the Behavioral Risk Factor Surveillance System and three national surveys
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Lin, Mei, Li, Chien-Hsun, Wei, Liang, Naavaal, Shillpa, Kolavic Gray, Shellie, Manz, Michael C., and Barker, Laurie
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Adult ,Male ,Behavioral Risk Factor Surveillance System ,Prevalence ,Humans ,Female ,Middle Aged ,Dental Health Surveys ,Nutrition Surveys ,Dental Health Services ,Article ,United States ,Aged - Abstract
OBJECTIVES: To compare estimated prevalence of past-year dental visit (PPYDV) among US adults aged ≥18 years from the Behavioral Risk Factor Surveillance System (BRFSS) to estimates from the Medical Expenditure Panel Survey (MEPS), National Health Interview Survey (NHIS), and National Health and Nutrition Examination Survey (NHANES). METHODS: We estimated PPYDV adjusted for covariates (age, race/ethnicity, education level, poverty status, edentulism) using BRFSS, MEPS, and NHIS 1999–2010, and NHANES 1999–2004. We tested trend in overall PPYDV for BRFSS, MEPS, and NHIS from 1999–2010. For 2002 and 2010, we calculated absolute differences (AD) and 95% confidence intervals (CI) in PPYDV between BRFSS and each of the other surveys overall and among subpopulations defined by covariates. We pooled NHANES 1999–2004 data for comparison with BRFSS 2002. RESULTS: From 1999 to 2010, BRFSS (68.5% vs. 67.5%), MEPS (43.5% vs. 39.7%), and NHIS (63.3% vs. 59.7%) showed small but significant decreases in overall PPYDV. In 2002, estimates for overall PPYDV were highest for BRFSS (70.0%) and lowest for MEPS (43.9%) with estimates for NHIS (61.5%) and NHANES (1999–2004: 58.1%) in between; the largest AD (26.2%, 95% CI: 25.0%–27.3%) was between BRFSS and MEPS. ADs were consistent in 2002 and 2010, overall and by covariates, except among edentate persons, where PPYDV estimates from BRFSS and NHIS were similar. CONCLUSIONS: Estimates of PPYDV from BRFSS were notably higher than estimates from MEPS, NHIS, or NHANES except among the edentate. Trends in PPYDV over time, however, were consistent across all surveys.
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- 2016
46. Prevalence of past-year dental visit among US adults, 1999-2010: comparison of trends and estimates between the Behavioral Risk Factor Surveillance System and three national surveys
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Lin, Mei, primary, Li, Chien-Hsun, additional, Wei, Liang, additional, Naavaal, Shillpa, additional, Kolavic Gray, Shellie, additional, Manz, Michael C., additional, and Barker, Laurie, additional
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- 2016
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47. An Unusual Cause of Rectal Stenosis
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Gruber, Maja, primary, Füglistaler, Ida, additional, Zettel, Andreas, additional, Fox, Mark, additional, and Manz, Michael, additional
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- 2016
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48. Locally adaptive discounting in multi sensor occupancy grid fusion
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Seeger, Christoph, primary, Manz, Michael, additional, Matters, Patrick, additional, and Hornegger, Joachim, additional
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- 2016
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49. Monitoring colonoscopy withdrawal time significantly improves the adenoma detection rate and the performance of endoscopists
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Vavricka, Stephan, additional, Sulz, Michael, additional, Degen, Lukas, additional, Rechner, Roman, additional, Manz, Michael, additional, Biedermann, Luc, additional, Beglinger, Christoph, additional, Peter, Shajan, additional, Safroneeva, Ekaterina, additional, Rogler, Gerhard, additional, and Schoepfer, Alain, additional
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- 2016
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50. Frequency of dental prophylaxis and glycemic control in type 2 diabetes
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Taylor, George W., Pritzel, Susan J., Manz, Michael C., Borgnakke, Wenche S., Eber, Robert M., and Bouman, Patricia D.
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Diabetes therapy -- Health aspects ,Diabetes therapy -- Analysis ,Type 2 diabetes -- Health aspects ,Type 2 diabetes -- Analysis - Abstract
This study was supported by a National Institute of Dental and Craniofacial Research, National Institutes of Health, Grant #R01DE13796. Purpose. Both diabetes and periodontal disease are common chronic diseases. It has been established that diabetes adversely affects periodontal health. Evidence is also increasing to support treating periodontal infection to improve glycemic control in people with diabetes. This evidence comes from reports of intervention studies evaluating the effect of treating patients with varying periodontitis severity in controlled settings. Reports on the relationship between frequency of dental prophylaxis and glycemic control are sparse. The purpose of this analysis was to test the hypothesis that people who report more frequent or more recent dental prophylaxes are more likely to have better glycemic control Methods and Materials. We analyzed screening data from 240 university hospital clinic and HMO subjects with type 2 diabetes, who were recruited for an ongoing clinical trial to investigate whether recency of dental prophylaxis appointments was associated with glycemic control as measured by level of hemoglobin A1c (HbA1c). Bivariable analysis and multiple regression modeling were conducted to evaluate associations of HbA1c with continuous and categorical variables collected from interviews and clinical examinations. The primary explanatory variables of interest were responses to interview questions on time elapsed since dental prophylaxis appointments. Results. In bivariable analysis of numerous demographic, medical, and behavioral variables, only oral diabetes medication/insulin usage status (P = .03) and doctor-recommended frequency of checking blood glucose levels (P < .01) showed statistically significant associations with HbA1c. Results from multiple regression modeling indicated that race/ethnicity, education level, and doctor-recommended frequency of checking blood glucose levels were significant predictors (P < .05), while diastolic blood pressure, low activity level, and current tobacco use were marginally non-significant predictors (P > .05). Time elapsed since dental prophylaxis appointments showed a positive but statistically non-significant association with HbA1c in both bivariable (P > .25) and regression analysis (P = .2). Conclusion. Further, more rigorous investigation of predictors of HbA1c is needed to determine if recency and frequency of dental prophylaxis contribute to glycemic control in subjects with diabetes., George W. Taylor, DMD, DrPH, and Robert M. Eber, DDS, MS are associate professors at the University of Michigan. Susan J. Pritzel, BS, MA, is an assistant professor at the [...]
- Published
- 2005
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