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288 results on '"Mansfield, L. A."'

2. Interleukin (IL)-1/IL-6-Inhibitor–Associated Drug Reaction With Eosinophilia and Systemic Symptoms (DReSS) in Systemic Inflammatory Illnesses

Author

Aamir, R., Abulaban, K., Adams, A., Lapsia, C. Aguiar, Akinsete, A., Akoghlanian, S., Al Manaa, M., AlBijadi, A., Allenspach, E., Almutairi, A., Alperin, R., Amarilyo, G., Ambler, W., Amoruso, M., Angeles-Han, S., Ardoin, S., Armendariz, S., Asfaw, L., Aviran Dagan, N., Bacha, C., Balboni, I., Balevic, S., Ballinger, S., Baluta, S., Barillas-Arias, L., Basiaga, M., Baszis, K., Baxter, S., Becker, M., Begezda, A., Behrens, E., Beil, E., Benseler, S., Bermudez-Santiago, L., Bernal, W., Bigley, T., Bingham, C., Binstadt, B., Black, C., Blackmon, B., Blakley, M., Bohnsack, J., Boneparth, A., Bradfield, H., Bridges, J., Brooks, E., Brothers, M., Brunner, H., Buckley, L., Buckley, M., Bukulmez, H., Bullock, D., Canna, S., Cannon, L., Canny, S., Cartwright, V., Cassidy, E., Castro, D., Chalom, E., Chang, J., Chang, M., Chang-Hoftman, A., Chen, A., Chiraseveenuprapund, P., Ciaglia, K., Co, D., Cohen, E., Collinge, J., Conlon, H., Connor, R., Cook, K., Cooper, A., Cooper, J., Corbin, K., Correll, C., Cron, R., Curry, M., Dalrymple, A., Datyner, E., Davis, T., De Ranieri, D., Dean, J., DeCoste, C., Dedeoglu, F., DeGuzman, M., Delnay, N., DeSantis, E., Devine, R., Dhalla, M., Dhanrajani, A., Dissanayake, D., Dizon, B., Drapeau, N., Drew, J., Driest, K., Du, Q., Duncan, E., Dunnock, K., Durkee, D., Dvergsten, J., Eberhard, A., Ede, K., Edelheit, B., Edens, C., El Tal, T., Elder, M., Elzaki, Y., Fadrhonc, S., Failing, C., Fair, D., Favier, L., Feldman, B., Fennell, J., Ferguson, P., Ferguson, I., Figueroa, C., Flanagan, E., Fogel, L., Fox, E., Fox, M., Franklin, L., Fuhlbrigge, R., Fuller, J., Furey, M., Futch-West, T., Gagne, S., Gennaro, V., Gerstbacher, D., Gilbert, M., Gironella, A., Glaser, D., Goh, I., Goldsmith, D., Gorry, S., Goswami, N., Gottlieb, B., Graham, T., Grevich, S., Griffin, T., Grim, A., Grom, A., Guevara, M., Hahn, T., Halyabar, O., Hamda Natur, M., Hammelev, E., Hammond, T., Harel, L., Harris, J., Harry, O., Hausmann, J., Hay, A., Hays, K., Hayward, K., Henderson, L., Henrickson, M., Hersh, A., Hickey, K., Hiraki, L., Hiskey, M., Hobday, P., Hoffart, C., Holland, M., Hollander, M., Hong, S., Horton, D., Horwitz, M., Hsu, J., Huber, A., Huberts, A., Huggins, J., Huie, L., Hui-Yuen, J., Ibarra, M., Imlay, A., Imundo, L., Inman, C., Jackson, A., James, K., Janow, G., Jared, S., Jiang, Y., Johnson, L., Johnson, N., Jones, J., Kafisheh, D., Kahn, P., Kaidar, K., Kasinathan, S., Kaur, R., Kessler, E., Kienzle, B., Kim, S., Kimura, Y., Kingsbury, D., Kitcharoensakkul, M., Klausmeier, T., Klein, K., Klein-Gitelman, M., Knight, A., Kovalick, L., Kramer, S., Kremer, C., Kudas, O., LaFlam, T., Lang, B., Lapidus, S., Lapin, B., Lasky, A., Lawler, C., Lawson, E., Laxer, R., Lee, P., Lee, T., Lee, A., Leisinger, E., Lentini, L., Lerman, M., Levinsky, Y., Levy, D., Li, S., Lieberman, S., Lim, L., Limenis, E., Lin, C., Ling, N., Lionetti, G., Livny, R., Lloyd, M., Lo, M., Long, A., Lopez-Peña, M., Lovell, D., Luca, N., Lvovich, S., Lytch, A., Ma, M., Machado, A., MacMahon, J., Madison, J., Mannion, M., Manos, C., Mansfield, L., Marston, B., Mason, T., Matchett, D., McAllister, L., McBrearty, K., McColl, J., McCurdy, D., McDaniels, K., McDonald, J., Meidan, E., Mellins, E., Mian, Z., Miettunen, P., Miller, M., Milojevic, D., Mitacek, R., Modica, R., Mohan, S., Moore, T., Moore, K., Moorthy, L., Moreno, J., Morgan, E., Moyer, A., Murante, B., Murphy, A., Muscal, E., Mwizerwa, O., Najafi, A., Nanda, K., Nasah, N., Nassi, L., Nativ, S., Natter, M., Nearanz, K., Neely, J., Newhall, L., Nguyen, A., Nigrovic, P., Nocton, J., Nolan, B., Nowicki, K., Oakes, R., Oberle, E., Ogbonnaya-Whittesley, S., Ogbu, E., Oliver, M., Olveda, R., Onel, K., Orandi, A., Padam, J., Paller, A., Pan, N., Pandya, J., Panupattanapong, S., Toledano, A. Pappo, Parsons, A., Patel, J., Patel, P., Patrick, A., Patrizi, S., Paul, S., Perfetto, J., Perron, M., Peskin, M., Ponder, L., Pooni, R., Prahalad, S., Puplava, B., Quinlan-Waters, M., Rabinovich, C., Rafko, J., Rahimi, H., Rampone, K., Ramsey, S., Randell, R., Ray, L., Reed, A., Reid, H., Reiff, D., Richins, S., Riebschleger, M., Rife, E., Riordan, M., Riskalla, M., Robinson, A., Robinson, L., Rodgers, L., Rodriquez, M., Rogers, D., Ronis, T., Rosado, A., Rosenkranz, M., Rosenwasser, N., Rothermel, H., Rothman, D., Rothschild, E., Roth-Wojcicki, E., Rouster-Stevens, K., Rubinstein, T., Rupp, J., Ruth, N., Sabbagh, S., Sadun, R., Santiago, L., Saper, V., Sarkissian, A., Scalzi, L., Schahn, J., Schikler, K., Schlefman, A., Schmeling, H., Schmitt, E., Schneider, R., Schulert, G., Schultz, K., Schutt, C., Seper, C., Sheets, R., Shehab, A., Shenoi, S., Sherman, M., Shirley, J., Shishov, M., Siegel, D., Singer, N., Sivaraman, V., Sloan, E., Smith, C., Smith, J., Smitherman, E., Soep, J., Son, Mary B., Sosna, D., Spencer, C., Spiegel, L., Spitznagle, J., Srinivasalu, H., Stapp, H., Steigerwald, K., Stephens, A., Sterba Rakovchik, Y., Stern, S., Stevens, B., Stevenson, R., Stewart, K., Stewart, W., Stingl, C., Stoll, M., Stringer, E., Sule, S., Sullivan, J., Sundel, R., Sutter, M., Swaffar, C., Swayne, N., Syed, R., Symington, T., Syverson, G., Szymanski, A., Taber, S., Tal, R., Tambralli, A., Taneja, A., Tanner, T., Tarvin, S., Tate, L., Taxter, A., Taylor, J., Tesher, M., Thakurdeen, T., Theisen, A., Thomas, B., Thomas, L., Thomas, N., Ting, T., Todd, C., Toib, D., Torok, K., Tory, H., Toth, M., Tse, S., Tsin, C., Twachtman-Bassett, J., Twilt, M., Valcarcel, T., Valdovinos, R., Vallee, A., Van Mater, H., Vandenbergen, S., Vannoy, L., Varghese, C., Vasquez, N., Vega-Fernandez, P., Velez, J., Verbsky, J., Verstegen, R., von Scheven, E., Vora, S., Wagner-Weiner, L., Wahezi, D., Waite, H., Walker, B., Walters, H., Waterfield, M., Waters, A., Weiser, P., Weiss, P., Weiss, J., Wershba, E., Westheuser, V., White, A., Widrick, K., Williams, C., Wong, S., Woolnough, L., Wright, T., Wu, E., Yalcindag, A., Yasin, S., Yeung, R., Yomogida, K., Zeft, A., Zhang, Y., Zhao, Y., Zhu, A., Saper, Vivian E., Tian, Lu, Verstegen, Ruud H.J., Conrad, Carol K., Cidon, Michal, Hopper, Rachel K., Kuo, Christin S., Osoegawa, Kazutoyo, Baszis, Kevin, Bingham, Catherine A., Ferguson, Ian, Hahn, Timothy, Horne, Annacarin, Isupova, Eugenia A., Jones, Jordan T., Kasapcopur, Özgür, Klein-Gitelman, Marisa S., Kostik, Mikhail M., Ozen, Seza, Phadke, Omkar, Prahalad, Sampath, Randell, Rachel L., Sener, Seher, Stingl, Cory, Abdul-Aziz, Rabheh, Akoghlanian, Shoghik, Al Julandani, Dalila, Alvarez, Marcela B., Bader-Meunier, Brigitte, Balay-Dustrude, Erin E., Balboni, Imelda, Baxter, Sarah K., Berard, Roberta A., Bhattad, Sagar, Bolaria, Roxana, Boneparth, Alexis, Cassidy, Elaine A., Co, Dominic O., Collins, Kathleen P., Dancey, Paul, Dickinson, Aileen M., Edelheit, Barbara S., Espada, Graciela, Flanagan, Elaine R., Imundo, Lisa F., Jindal, Ankur K., Kim, Hyoun-Ah, Klaus, Günter, Lake, Carol, Lapin, W. Blaine, Lawson, Erica F., Marmor, Itay, Mombourquette, Joy, Ogunjimi, Benson, Olveda, Rebecca, Ombrello, Michael J., Onel, Karen, Poholek, Catherine, Ramanan, Athimalaipet V., Ravelli, Angelo, Reinhardt, Adam, Robinson, Amanda D., Rouster-Stevens, Kelly, Saad, Nadine, Schneider, Rayfel, Selmanovic, Velma, Sefic Pasic, Irmina, Shenoi, Susan, Shilo, Natalie R., Soep, Jennifer B., Sura, Angeli, Taber, Sarah F., Tesher, Melissa, Tibaldi, Jessica, Torok, Kathryn S., Tsin, Cathy Mei, Vasquez-Canizares, Natalia, Villacis Nunez, Diana S., Way, Emily E., Whitehead, Benjamin, Zemel, Lawrence S., Sharma, Surbhi, Fernández-Viña, Marcelo A., and Mellins, Elizabeth D.

Published
2024
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5. Using stealth marketing techniques to increase physical activity and decrease sedentary time in the workplace: a feasibility study investigating the spill-overs of employee pro-environmental behaviour

Author

Manika, D., Blokland, Y., Smith, L., Mansfield, L., and Klonizakis, M.

Subjects
stealth marketing intervention, employee physical activity, employee pro-environmental behaviour, spillovers, feasibility, pilot study, Business, HF5001-6182
Abstract

Sedentary lifestyles have adverse effects on health and wellbeing and are especially prevalent amongst office-based employees. This project goes above and beyond currently existing physical activity initiatives in the workplace, by examining the feasibility of using a "Bait-and-Tease" stealth marketing intervention promoting increased physical activity and reduction of sedentary behaviour in the workplace amongst office-based employees. The intervention focused on promoting employee pro-environmental behaviour in the workplace (i.e., energy saving and recycling). This was the "Bait" part of the technique, which made no reference to physical activity. The spillovers of employee pro-environmental behaviour change on employee physical activity and sedentary behaviour were then evaluated. This was followed by a reveal stage, the "Tease" part of the technique, where the link between health and the environment was made explicit (e.g., taking the stairs instead of the elevator saves energy while also increasing walking time) and participants were informed of the true purpose of the intervention. Initial employee focus groups, grounded on the Behaviour Change Wheel framework, fed into an intervention co-development workshop. The developed intervention, which included an informational campaign and a green champion, was piloted within a Higher Education Institution and targeted academics, professional service members, and postgraduate research students as university employees with office-based jobs. The pilot involved an intervention and a control-group, with a "before" and "after" research design. Both self-reported (i.e., employee surveys measuring pro-environmental behaviour) and observational (i.e., tracking walking and standing time via a mobile application, recording sedentary time and counting stairs via trained observers) data were collected. Results indicate that the intervention was found feasible and the pilot study shows potential for large-scale implementation, even though the pilot sample size was small. The goals of the study were achieved and problems in relation to recruitment, adherence and measurements were identified with multiple future research directions.

Published
2021

6. Soft X-ray absorption spectroscopy investigation of the surface chemistry and treatments of copper indium gallium diselenide (CIGS)

Author

Schwartz, C, Nordlund, D, Sokaras, D, Contreras, M, Weng, TC, Mansfield, L, Hurst, KE, Dameron, A, Ramanathan, K, Prendergast, D, and Christensen, ST

Subjects
Copper-indium-gallium-selenide, CIGS, XAS, Chemical bath deposition, Surface analysis, Energy, Engineering, Chemical Sciences, Physical Sciences
Abstract

The surface and near surface structure of copper-indium-gallium-selenide (CIGS) absorber layers is integral to the producing a high-quality photovoltaic junction. By using X-ray absorption spectroscopy (XAS) and monitoring multiple elemental absorption edges with both theory and experiment, we are able to identify several features of the surface of CIGS as a function of composition and surface treatments. The XAS data shows trends in the near surface region of oxygen, copper, indium and gallium species as the copper content is varied in the films. The oxygen surface species are also monitored through a series of experiments that systematically investigates the effects of water and various solutions of: ammonium hydroxide, cadmium sulfate, and thiourea. These being components of cadmium sulfide chemical bath deposition (CBD). Characteristics of the CBD are correlated with a restorative effect that produces as normalized, uniform surface chemistry as measured by XAS. This surface chemistry is found in CIGS solar cells with excellent power conversion efficiency (

Published
2017

7. Comparative Effectiveness of a Second Tumor Necrosis Factor Inhibitor Versus a Non–Tumor Necrosis Factor Biologic in the Treatment of Patients With Polyarticular‐Course Juvenile Idiopathic Arthritis

Author

Mannion, Melissa L., Amin, Shahla, Balevic, Stephen, Chang, Min‐Lee, Correll, Colleen K., Kearsley‐Fleet, Lianne, Hyrich, Kimme L., Beukelman, Timothy, Aamir, R., Abulaban, K., Adams, A., Aguiar Lapsia, C., Akinsete, A., Akoghlanian, S., Al Manaa, M., AlBijadi, A., Allenspach, E., Almutairi, A., Alperin, R., Amarilyo, G., Ambler, W., Amoruso, M., Angeles‐Han, S., Ardoin, S., Armendariz, S., Asfaw, L., Aviran Dagan, N., Bacha, C., Balboni, I., Balevic, S., Ballinger, S., Baluta, S., Barillas‐Arias, L., Basiaga, M., Baszis, K., Baxter, S., Becker, M., Begezda, A., Behrens, E., Beil, E., Benseler, S., Bermudez‐Santiago, L., Bernal, W., Bigley, T., Bingham, C., Binstadt, B., Black, C., Blackmon, B., Blakley, M., Bohnsack, J., Boneparth, A., Bradfield, H., Bridges, J., Brooks, E., Brothers, M., Brunner, H., Buckley, L., Buckley, M., Buckley, M., Bukulmez, H., Bullock, D., Canna, S., Cannon, L., Canny, S., Cartwright, V., Cassidy, E., Castro, D., Chalom, E., Chang, J., Chang, M., Chang, J., Chang‐Hoftman, A., Chen, A., Chiraseveenuprapund, P., Ciaglia, K., Co, D., Cohen, E., Collinge, J., Conlon, H., Connor, R., Cook, K., Cooper, A., Cooper, J., Corbin, K., Correll, C., Cron, R., Curry, M., Dalrymple, A., Datyner, E., Davis, T., De Ranieri, D., Dean, J., DeCoste, C., Dedeoglu, F., DeGuzman, M., Delnay, N., DeSantis, E., Devine, R., Dhalla, M., Dhanrajani, A., Dissanayake, D., Dizon, B., Drapeau, N., Drew, J., Driest, K., Du, Q., Duncan, E., Dunnock, K., Durkee, D., Dvergsten, J., Eberhard, A., Ede, K., Edelheit, B., Edens, C., El Tal, T., Elder, M., Elzaki, Y., Fadrhonc, S., Failing, C., Fair, D., Favier, L., Feldman, B., Fennell, J., Ferguson, P., Ferguson, I., Figueroa, C., Flanagan, E., Fogel, L., Fox, E., Fox, M., Franklin, L., Fuhlbrigge, R., Fuller, J., Furey, M., Futch‐West, T., Gagne, S., Gennaro, V., Gerstbacher, D., Gilbert, M., Gironella, A., Glaser, D., Goh, I., Goldsmith, D., Gorry, S., Goswami, N., Gottlieb, B., Graham, T., Grevich, S., Griffin, T., Grim, A., Grom, A., Guevara, M., Hahn, T., Halyabar, O., Hamda Natur, M., Hammelev, E., Hammond, T., Harel, L., Harris, J., Harry, O., Hausmann, J., Hay, A., Hays, K., Hayward, K., Henderson, L., Henrickson, M., Hersh, A., Hickey, K., Hiraki, L., Hiskey, M., Hobday, P., Hoffart, C., Holland, M., Hollander, M., Hong, S., Horton, D., Horwitz, M., Hsu, J., Huber, A., Huberts, A., Huggins, J., Huie, L., Hui‐Yuen, J., Ibarra, M., Imlay, A., Imundo, L., Inman, C., Jackson, A., James, K., Janow, G., Jared, S., Jiang, Y., Johnson, L., Johnson, N., Jones, J., Kafisheh, D., Kahn, P., Kaidar, K., Kasinathan, S., Kaur, R., Kessler, E., Kienzle, B., Kim, S., Kimura, Y., Kingsbury, D., Kitcharoensakkul, M., Klausmeier, T., Klein, K., Klein‐Gitelman, M., Knight, A., Kovalick, L., Kramer, S., Kremer, C., Kudas, O., LaFlam, T., Lang, B., Lapidus, S., Lapin, B., Lasky, A., Lawler, C., Lawson, E., Laxer, R., Lee, P., Lee, P., Lee, T., Lee, A., Leisinger, E., Lentini, L., Lerman, M., Levinsky, Y., Levy, D., Li, S., Lieberman, S., Lim, L., Limenis, E., Lin, C., Ling, N., Lionetti, G., Livny, R., Lloyd, M., Lo, M., Long, A., Lopez‐Peña, M., Lovell, D., Luca, N., Lvovich, S., Lytch, A., Ma, M., Machado, A., MacMahon, J., Madison, J., Mannion, M., Manos, C., Mansfield, L., Marston, B., Mason, T., Matchett, D., McAllister, L., McBrearty, K., McColl, J., McCurdy, D., McDaniels, K., McDonald, J., Meidan, E., Mellins, E., Mian, Z., Miettunen, P., Miller, M., Milojevic, D., Mitacek, R., Modica, R., Mohan, S., Moore, T., Moore, K., Moorthy, L., Moreno, J., Morgan, E., Moyer, A., Murante, B., Murphy, A., Muscal, E., Mwizerwa, O., Najafi, A., Nanda, K., Nasah, N., Nassi, L., Nativ, S., Natter, M., Nearanz, K., Neely, J., Newhall, L., Nguyen, A., Nigrovic, P., Nocton, J., Nolan, B., Nowicki, K., Oakes, R., Oberle, E., Ogbonnaya‐Whittesley, S., Ogbu, E., Oliver, M., Olveda, R., Onel, K., Orandi, A., Padam, J., Paller, A., Pan, N., Pandya, J., Panupattanapong, S., Toledano, A. Pappo, Parsons, A., Patel, J., Patel, P., Patrick, A., Patrizi, S., Paul, S., Perfetto, J., Perron, M., Peskin, M., Ponder, L., Pooni, R., Prahalad, S., Puplava, B., Quinlan‐Waters, M., Rabinovich, C., Rafko, J., Rahimi, H., Rampone, K., Ramsey, S., Randell, R., Ray, L., Reed, A., Reed, A., Reid, H., Reiff, D., Richins, S., Riebschleger, M., Rife, E., Riordan, M., Riskalla, M., Robinson, A., Robinson, L., Rodgers, L., Rodriquez, M., Rogers, D., Ronis, T., Rosado, A., Rosenkranz, M., Rosenwasser, N., Rothermel, H., Rothman, D., Rothschild, E., Roth‐Wojcicki, E., Rouster‐Stevens, K., Rubinstein, T., Rupp, J., Ruth, N., Sabbagh, S., Sadun, R., Santiago, L., Saper, V., Sarkissian, A., Scalzi, L., Schahn, J., Schikler, K., Schlefman, A., Schmeling, H., Schmitt, E., Schneider, R., Schulert, G., Schultz, K., Schutt, C., Seper, C., Sheets, R., Shehab, A., Shenoi, S., Sherman, M., Shirley, J., Shishov, M., Siegel, D., Singer, N., Sivaraman, V., Sloan, E., Smith, C., Smith, J., Smitherman, E., Soep, J., Son, Mary B., Sosna, D., Spencer, C., Spiegel, L., Spitznagle, J., Srinivasalu, H., Stapp, H., Steigerwald, K., Stephens, A., Sterba Rakovchik, Y., Stern, S., Stevens, B., Stevenson, R., Stewart, K., Stewart, W., Stingl, C., Stoll, M., Stringer, E., Sule, S., Sullivan, J., Sundel, R., Sutter, M., Swaffar, C., Swayne, N., Syed, R., Symington, T., Syverson, G., Szymanski, A., Taber, S., Tal, R., Tambralli, A., Taneja, A., Tanner, T., Tarvin, S., Tate, L., Taxter, A., Taylor, J., Tesher, M., Thakurdeen, T., Theisen, A., Thomas, B., Thomas, L., Thomas, N., Ting, T., Todd, C., Toib, D., Toib, D., Torok, K., Tory, H., Toth, M., Tse, S., Tsin, C., Twachtman‐Bassett, J., Twilt, M., Valcarcel, T., Valdovinos, R., Vallee, A., Van Mater, H., Vandenbergen, S., Vannoy, L., Varghese, C., Vasquez, N., Vega‐Fernandez, P., Velez, J., Verbsky, J., Verstegen, R., Scheven, E., Vora, S., Wagner‐Weiner, L., Wahezi, D., Waite, H., Walker, B., Walters, H., Waterfield, M., Waters, A., Weiser, P., Weiss, P., Weiss, J., Wershba, E., Westheuser, V., White, A., Widrick, K., Williams, C., Wong, S., Woolnough, L., Wright, T., Wu, E., Yalcindag, A., Yasin, S., Yeung, R., Yomogida, K., Zeft, A., Zhang, Y., Zhao, Y., and Zhu, A.

Abstract

The objective of this study was to compare the effectiveness of a second tumor necrosis factor inhibitor (TNFi) versus a non‐TNFi biologic following discontinuation of a TNFi for patients with polyarticular‐course juvenile idiopathic arthritis (pJIA). Using the Childhood Arthritis and Rheumatology Research Alliance Registry, patients with pJIA who started receiving a second biologic following a first TNFi were identified. Patients were required to have no active uveitis on the index date and a visit six months after the index date. Outcome measures included Clinical Juvenile Arthritis Disease Activity Score with a maximum of 10 active joints (cJADAS10), cJADAS10 inactive disease (ID; ≤2.5) and cJADAS10 minimal disease activity (MiDA; ≤5). Multiple imputation was used to account for missing data. Adjusted odds ratios (aORs) were calculated using propensity score quintiles to compare outcomes at six months following second biologic initiation. There were 216 patients included, 84% initially received etanercept, and most patients stopped receiving it because of its ineffectiveness (74%). A total of 183 (85%) started receiving a second TNFi, and 33 (15%) started receiving a non‐TNFi. Adalimumab was the most common second biologic received (71% overall, 84% of second TNFi), and tocilizumab was the most common non‐TNFi second biologic received (9% overall, 58% of non‐TNFi). There was no difference between receiving TNFi versus non‐TNFi in cJADAS10 ID (29% vs 25%; aOR 1.23, 95% confidence interval [CI] 0.47–3.20) or at least MiDA (43% vs 39%; aOR 1.11, 95% CI 0.47–2.62) at six months. Most patients with pJIA started receiving TNFi rather than non‐TNFi as their second biologic, and there were no differences in disease activity at six months.

Published
2024
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8. Uncertainty Quantification of a Machine Learning Subgrid‐Scale Parameterization for Atmospheric Gravity Waves.

Author

Mansfield, L. A. and Sheshadri, A.

Subjects
*GRAVITY waves, *ATMOSPHERIC waves, *MACHINE learning, *PARAMETERIZATION, *ATMOSPHERIC models
Abstract

Subgrid‐scale processes, such as atmospheric gravity waves (GWs), play a pivotal role in shaping the Earth's climate but cannot be explicitly resolved in climate models due to limitations on resolution. Instead, subgrid‐scale parameterizations are used to capture their effects. Recently, machine learning (ML) has emerged as a promising approach to learn parameterizations. In this study, we explore uncertainties associated with a ML parameterization for atmospheric GWs. Focusing on the uncertainties in the training process (parametric uncertainty), we use an ensemble of neural networks to emulate an existing GW parameterization. We estimate both offline uncertainties in raw NN output and online uncertainties in climate model output, after the neural networks are coupled. We find that online parametric uncertainty contributes a significant source of uncertainty in climate model output that must be considered when introducing NN parameterizations. This uncertainty quantification provides valuable insights into the reliability and robustness of ML‐based GW parameterizations, thus advancing our understanding of their potential applications in climate modeling. Plain Language Summary: Climate models are unable to resolve processes that vary on length and time scales smaller than the model resolution and timestep. For example, atmospheric gravity waves (GWs), which are waves created when winds encounter disturbances to the flow, such as mountains, convection and fronts, can have wavelengths smaller than the spacing between grid cells. Climate models use "parameterizations" to capture the effect of these processes. Machine learning based parameterizations are becoming popular because they can learn relationships purely from data. However, we do not have a good understanding of the uncertainties introduced through machine learning parameterizations. This study estimates uncertainties associated with training a neural network (NN) GW parameterization. We explore uncertainties in the NN output, as well as the uncertainties in the climate model output, when the NN is used for the GW parameterization. Key Points: Using ensembles of neural networks, we learn parametric uncertainties associated with an emulator of a gravity wave parameterizationWhen coupled to the climate model, the ensemble of neural networks reveals increased climate variabilityParametric uncertainty dominates the Quasi‐Biennial Oscillation statistics, although polar vortex properties remain robust to parameters [ABSTRACT FROM AUTHOR]

Published
2024
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11. Variation in the provision and practice of implant-based breast reconstruction in the UK: Results from the iBRA national practice questionnaire

Author

Barnes, N.L.P., Blazeby, J.M., Branford, O.A., Conroy, E.J., Cutress, R.I., Gardiner, M.D., Holcombe, C., Jain, A., McEvoy, K., Mills, N., Mylvaganam, S., Potter, S., Skillman, J.M., Teasdale, E.M., Thrush, S., Whisker, L.J., Williamson, P.R., Tang, L., Nguyen, D., Johnson, R., Muralikrishnan, V., Chopra, S., Reid, A., Benyon, S., Murphy, C., Soliman, F., Lefemine, V., Saha, S., Ogedegbe, K., Olyinka, O.S., Dicks, J.R., Manoloudakis, N., Conroy, F., Irwin, G., McIntosh, S., Michalakis, I., Hignett, S., Linforth, R., Rathinaezhil, R., Osman, H., Anesti, K., Griffiths, M., Jacklin, R., Waterworth, A., Foulkes, R., Davies, E., Bisarya, K., Allan, A., Leon-Villapalos, J., Mazari, F.A.K., Azmy, I., George, S., Fahmy, F.S., Hargreaves, A., Seward, J., Henton, J., Collin, T., Mallon, P., Turner, J., Sarakbi, W., Athanasiou, I., Rogers, C., Youssef, M., Graja, T., Huf, S., Deol, H., Brindle, R., Gawne, S., Egbeare, D., Dash, I., Galea, M., Laws, S., Tayeh, S., Parvanta, L., Down, S., Westbroek, D., Roberts, J.W., Massey, J., Turton, P., Achuthan, R., Fawzy, M., Dickson, M., Carmichael, A.R., Akingboye, A., James, R., Kirkpatrick, K., Nael, E., Vidya, R., Thorne, A., Rostom, M., Depasquale, I., Cawthorn, S.J., Gangamihardja, T., Joglekar, S., Smith, J., Halka, A., MacMillan, D., Clark, S., Pearce, B., Mansfield, L., King, I., Hazari, A., Smith, B., Volleamere, A.J., Ferguson, D., Barnes, N., Knight, A., MacNeill, F., Conway, A., Irvine, T., Mylavaganam, S., Dunne, N., Kohlhardt, S., Hoo, C., Kirk, S., Hu, J., Ledwidge, S., Tang, S., Banerjee, D., Waheed, S., Voynov, V., Soumian, S., Henderson, J., Harvey, J., Robertson, S., Waters, R., Carbone, A., Skillman, J., Farooq, Ansar, Tafazal, H., Clarke, D., Cocker, D., Lai, L.M., Winter Beatty, J., Barkeji, M., Vinayagam, R., Mullan, M., Osborne, C., Baker, E., Piper, J., Mylvaganam, Senthurun, Conroy, Elizabeth, Williamson, Paula R., Barnes, Nicola L.P., Cutress, Ramsey I., Gardiner, Matthew D., Jain, Abhilash, Skillman, Joanna M., Thrush, Steven, Whisker, Lisa J., Blazeby, Jane M., Potter, Shelley, and Holcombe, Christopher

Published
2017
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14. PROTOCOL: A mixed methods systematic review on the effects of arts interventions for at‐risk and offending children and young people on behavioural, psychosocial, cognitive and offending outcomes

Author

Mansfield, L, Daykin, N, O'Connell, NE, Bailey, D, Forde, L, Smith, R, and Gifford, J

Subjects
General Social Sciences
Abstract

Supporting Information: available online at https://onlinelibrary.wiley.com/doi/10.1002/cl2.1298#support-information-section (cl21298-sup-0001-supmat.docx 15.6 KB). Copyright © 2023 The Authors. This is the protocol for a Campbell systematic review. The proposed systematic review question is: What is the effectiveness of arts interventions for at-risk and offending children and young people (8-25 years)? There are three objectives: (1) To evaluate evidence on the effectiveness and impact of arts interventions on keeping children safe from involvement in violence and crime; (2) To synthesise evidence on factors impacting the implementation of arts interventions, and barriers and facilitators to participation and achievement of intended outcomes; (3) To develop a theory-of-change approach to ensure the development of an evidence-led framework of the processes by which arts interventions might work in preventing offending behaviours. Youth Endowment Foundation.

Published
2023

15. Implications for sequencing of biologic therapy and choice of second anti-TNF in patients with inflammatory bowel disease: Results from the IMmunogenicity to Second Anti-TNF therapy (IMSAT) therapeutic drug monitoring study

Author

Chanchlani, N, Lin, S, Auth, MK, Lee, CL, Robbins, H, Looi, S, Murugesan, SV, Riley, T, Preston, C, Stephenson, S, Cardozo, W, Sonwalkar, SA, Allah-Ditta, M, Mansfield, L, Durai, D, Baker, M, London, I, London, E, Gupta, S, Di Mambro, A, Murphy, A, Gaynor, E, Jones, KDJ, Claridge, A, Sebastian, S, Ramachandran, S, Selinger, CP, Borg-Bartolo, SP, Knight, P, Sprakes, MB, Burton, J, Kane, P, Lupton, S, Fletcher, A, Gaya, DR, Colbert, R, Seenan, JP, MacDonald, J, Lynch, L, McLachlan, I, Shields, S, Hansen, R, Gervais, L, Jere, M, Akhtar, M, Black, K, Henderson, P, Russell, RK, Lees, CW, Derikx, LAAP, Lockett, M, Betteridge, F, De Silva, A, Hussenbux, A, Beckly, J, Bendall, O, Hart, JW, Thomas, A, Hamilton, B, Gordon, C, Chee, D, McDonald, TJ, Nice, R, Parkinson, M, Gardner-Thorpe, H, Butterworth, JR, Javed, A, Al-Shakhshir, S, Yadagiri, R, Maher, S, Pollok, RCG, Ng, T, Appiahene, P, Donovan, F, Lok, J, Chandy, R, Jagdish, R, Baig, D, Mahmood, Z, Marsh, L, Moss, A, Abdulgader, A, Kitchin, A, Walker, GJ, George, B, Lim, Y-H, Gulliver, J, Bloom, S, Theaker, H, Carlson, S, Cummings, JRF, Livingstone, R, Beale, A, Carter, JO, Bell, A, Coulter, A, Snook, J, Stone, H, Kennedy, NA, Goodhand, JR, Ahmad, T, and IMSAT study investigators

Abstract

BACKGROUND: Anti-drug antibodies are associated with treatment failure to anti-TNF agents in patients with inflammatory bowel disease (IBD). AIM: To assess whether immunogenicity to a patient's first anti-TNF agent would be associated with immunogenicity to their second, irrespective of drug sequence METHODS: We conducted a UK-wide, multicentre, retrospective cohort study to report rates of immunogenicity and treatment failure of second anti-TNF therapies in 1058 patients with IBD who underwent therapeutic drug monitoring for both infliximab and adalimumab. The primary outcome was immunogenicity to the second anti-TNF drug, defined at any timepoint as an anti-TNF antibody concentration ≥9 AU/ml for infliximab and ≥6 AU/ml for adalimumab. RESULTS: In patients treated with infliximab and then adalimumab, those who developed antibodies to infliximab were more likely to develop antibodies to adalimumab, than patients who did not develop antibodies to infliximab (OR 1.99, 95%CI 1.27-3.20, p = 0.002). Similarly, in patients treated with adalimumab and then infliximab, immunogenicity to adalimumab was associated with subsequent immunogenicity to infliximab (OR 2.63, 95%CI 1.46-4.80, p

Published
2022

17. ESICM LIVES 2016: part two: Milan, Italy. 1–5 October 2016

Author

Sivakumar, S., Taccone, F. S., Desai, K. A., Lazaridis, C., Skarzynski, M., Sekhon, M., Henderson, W., Griesdale, D., Chapple, L., Deane, A., Williams, L., Strickland, R., Lange, K., Heyland, D., Chapman, M., Rowland, M. J., Garry, P., Westbrook, J., Corkill, R., Antoniades, C. A., Pattinson, K. T., Fatania, G., Strong, A. J., Myers, R. B., Lazaridis, C., Jermaine, C. M., Robertson, C. S., Rusin, C. G., Hofmeijer, J., Sondag, L., Tjepkema-Cloostermans, M. C., Beishuizen, A., Bosch, F. H., van Putten, M. J. A. M., Carteron, L., Patet, C., Solari, D., Oddo, M., Ali, M. A., Dias, C., Almeida, R., Vaz-Ferreira, A., Silva, J., Monteiro, E., Cerejo, A., Rocha, A. P., Elsayed, A. A., Abougabal, A. M., Beshey, B. N., Alzahaby, K. M., Pozzebon, S., Ortiz, A. Blandino, Cristallini, S., Lheureux, O., Brasseur, A., Vincent, J. L., Creteur, J., Taccone, F. S., Hravnak, M., Yousef, K., Chang, Y., Crago, E., Friedlander, R. M., Abdelmonem, S. A., Tahon, S. A., Helmy, T. A., Meligy, H. S., Puig, F., Dunn-Siegrist, I., Pugin, J., Gupta, S., Govil, D., Srinivasan, S., Patel, S. J., N, J. K., Gupta, A., Tomar, D. S., Shafi, M., Harne, R., Arora, D. P., Talwar, N., Mazumdar, S., Papakrivou, E. E., Makris, D., Manoulakas, E., Tsolaki, B., Karadodas, B., Zakynthinos, E., Garcia, I. Palacios, Martin, A. Diaz, Encinares, V. Sanchez, Ibañez, M. Pachón, Montero, J. Garnacho, Labrador, G., Cangueiro, T. Cebrero, Poulose, V., Koh, J., Kam, J. W., Yeter, H., Kara, A., Aktepe, O., Topeli, A., Tsolakoglou, I., Intas, G., Stergiannis, P., Kolaros, A. A., Chalari, E., Athanasiadou, E., Martika, A., Fildisis, G., Faivre, V., Mengelle, C., Favier, B., Payen, D., Poppe, A., Winkler, M. S., Mudersbach, E., Schreiber, J., Wruck, M. L., Schwedhelm, E., Kluge, S., Zöllner, C., Tavladaki, T., Spanaki, A. M., Dimitriou, H., Kondili, E., Choulaki, C., Meleti, E., Kafetzopoulos, D., Georgopoulos, D., Briassoulis, G., la Torre, A. García-de, de la Torre-Prados, M. V., Tsvetanova-Spasova, T., Nuevo-Ortega, P., Rueda-Molina, C., Fernández-Porcel, A., Camara-Sola, E., Salido-Díaz, L., García-Alcántara, A., Tavladaki, T., Spanaki, A. M., Dimitriou, H., Kondili, E., Choulaki, C., Meleti, D. E., Kafetzopoulos, D., Georgopoulos, D., Briassoulis, G., Suberviola, B., Riera, J., Rellan, L., Sanchez, M., Robles, J. C., Lopez, E., Vicente, R., Miñambres, E., Santibañez, M., Le Guen, M., Moore, J., Mason, N., Windpassinger, M., Plattner, O., Mascha, E., Sessler, D. I., Research, Outcomes, Melia, U., Fontanet, J., van den Berg, J. P., Struys, M. M. R. F., Vereecke, H. E. M., Jensen, E. W., Rood, P. J. T., van de Schoor, F., van Tertholen, K., Pickkers, P., van den Boogaard, M., Beardow, Z. J., Redhead, H., Paramasivam, K., Numan, T., van den Boogaard, M., Kamper, A. M., Rood, P., Peelen, L. M., Zeman, P. M., Slooter, A. J., van Ewijk, C. E., Jacobs, G. E., Girbes, A. R. J., Myatra, S. N., Harish, M. M., Prabu, N. R., Siddiqui, S., Kulkarni, A. P., Divatia, J. V., Murbach, L. D., Leite, M. A., Osaku, E. F., Costa, C. R. L. M., Pelenz, M., Neitzke, N. M., Moraes, M. M., Jaskowiak, J. L., Silva, M. M. M., Zaponi, R. S., Abentroth, L. R. L., Ogasawara, S. M., Jorge, A. C., Duarte, P. A. D., Hernández-Sánchez, N., Sánchez-Hurtado, L. A., García-Guillen, F. J., Ñamendys-Silva, S. A., Maghsoudi, B., Emami, M., Khosravi, M. B., Zand, F., Tabatabaie, H. R., Masjedi, M., Sabetiyan, G., Mokri, A., Troubleyn, J., Diltoer, M., Jacobs, R., Nguyen, D. N., De Waele, E., De Regt, J., Honoré, P. M., Van Gorp, V., Spapen, H. D., Contreras, R. S., Toapanta, N. D., Moreno, G., Sabater, J., Torrado, H., Gonzalez, M., Marin, M., Farigola, E., Gonzalez, A., Fernandez, J., Vera, A., Gisbert, X., Juliá, C., Uya, J., Corral, L., Elias-Jones, I., Gemmell, L., MacKay, A., Randall, D., Adwaney, A., Blunden, M., Prowle, J. R., Kirwan, C. J., Thomas, N., Martin, A., Owen, H., Darwin, L., Conway, D., Atkinson, D., Sharman, M., Moore, J., Barbanti, C., Amour, J., Gaudard, P., Rozec, B., Mauriat, P., M’rini, M., Leger, P. L., Cambonie, G., Liet, J. M., Girard, C., Laroche, S., Damas, P., Assaf, Z., Loron, G., Lecourt, L., Pouard, P., Randall, D., Adwaney, A., Blunden, M., Prowle, J.R., Kirwan, C. J., Kim, S. H., Na, S., Kim, J., Oh, S. Y., Jung, C. W., Yoo, S. H., Min, S. H., Chung, E. J., Lee, H., Lee, N. J., Lee, K. W., Suh, K. S., Ryu, H. G., Marshall, D. C., Goodson, R. J., Salciccioli, J. D., Shalhoub, J., Potter, E. K., Kirk-Bayley, J., Karanjia, N. D., Forni, L. G., Creagh-Brown, B. C., Bossy, M., Nyman, M., Tailor, A., Creagh-Brown, B., D’Antini, D., Spadaro, S., Valentino, F., Sollitto, F., Cinnella, G., Mirabella, L., Calvo, F. J. Redondo, Bejarano, N., Padilla, D., Baladron, V., Villajero, P., Villazala, R., Redondo, J., Yuste, A. S., Liu, J., Shen, F., Teboul, J. L., Anguel, N., Beurton, A., Bezaz, N., Richard, C., Monnet, X., Fossali, T., Colombo, R., Ottolina, D., Rossetti, M., Mazzucco, C., Marchi, A., Porta, A., Catena, E., Tollisen, K. H., Andersen, G. Ø., Heyerdahl, F., Jacobsen, D., de Waard, M. C., Girbes, A. R. J., van IJzendoorn, M. C. O., Buter, H., Kingma, W. P., Navis, G. J., Boerma, E. C., Rulisek, J., Balik, M., Zacharov, S., Kim, H. S., Jeon, S. J., Namgung, H., Lee, E., Lee, E., Cho, Y. J., Lee, Y. J., Huang, A., Cioccari, L., Luethi, N., Mårtensson, J., Bellomo, R., Forsberg, M., Edman, G., Höjer, J., Forsberg, S., Freile, M. T. Chiquito, Hidalgo, F. N., Molina, J. A. Martinez, Lecumberri, R., Rosselló, A. Figuerola, Travieso, P. Medrano, Leon, G. Tuero, Sanchez, J. Gonzalez, Frias, L. Sahuquillo, Rosello, D. Balsells, Verdejo, J. A. Garcia, Serrano, J. A. Noria, Winterwerp, D., van Galen, T., Vazin, A., Karimzade, I., Zand, A., Ozen, E., Ekemen, S., Akcan, A., Sen, E., Yelken, B. Buyukkidan, Kureshi, N., Fenerty, L., Thibault-Halman, G., Erdogan, M., Walling, S., Green, R. S., Clarke, D. B., Briassoulis, P., Kalimeris, K., Ntzouvani, A., Nomikos, T., Papaparaskeva, K., Politi, E., Kostopanagiotou, G., Crewdson, K., Rehn, M., Weaver, A., Brohi, K., Lockey, D., Wright, S., Thomas, K., Baker, C., Mansfield, L., Stafford, V., Wade, C., Watson, G., Bryant, A., Chadwick, T., Shen, J., Wilkinson, J., Furneval, J., Henderson, A., Hugill, K., Howard, P., Roy, A., Bonner, S., Baudouin, S., Ramírez, C. Sánchez, Escalada, S. Hípola, Viera, M. A. Hernández, Santana, M. Cabrera, Balcázar, L. Caipe, Monroy, N. Sangil, Campelo, F. Artiles, Vázquez, C. F. Lübbe, Santana, P. Saavedra, Santana, S. Ruiz, Carteron, L., Patet, C., Quintard, H., Solari, D., Bouzat, P., Oddo, M., Wollersheim, T., Malleike, J., Haas, K., Carbon, N., Schneider, J., Birchmeier, C., Fielitz, J., Spuler, S., Weber-Carstens, S., Enseñat, L., Pérez-Madrigal, A., Saludes, P., Proença, L., Gruartmoner, G., Espinal, C., Mesquida, J., Huber, W., Eckmann, M., Elkmann, F., Gruber, A., Lahmer, T., Mayr, U., Herner, A., Schellnegger, R., Schneider, J., Schmid, R. M., Ayoub, W., Samy, W., Esmat, A., Battah, A., Mukhtar, S., Mongkolpun, W., Cortés, D. Orbegozo, Cordeiro, C. P. R., Vincent, J. L., Creteur, J., Funcke, S., Groesdonk, H., Saugel, B., Wagenpfeil, G., Wagenpfeil, S., Reuter, D. A., Fernandez, M. M., Fernandez, R., Magret, M., González-Castro, A., Bouza, M. T., Ibañez, M., García, C., Balerdi, B., Mas, A., Arauzo, V., Añón, J. M., Ruiz, F., Ferreres, J., Tomás, R., Alabert, M., Tizón, A. I., Altaba, S., Llamas, N., Goligher, E C., Fan, E., Herridge, M., Vorona, S., Sklar, M., Dres, M., Rittayamai, N., Lanys, A., Urrea, C., Tomlinson, G., Reid, W. D., Rubenfeld, G. D., Kavanagh, B. P., Brochard, L. J., Ferguson, N. D., Neto, A. Serpa, de Abreu, M. Gama, Pelosi, P., Schultz, M. J., Guérin, C., Papazian, L., Reignier, J., Ayzac, L., Loundou, A., Forel, J. M., Rolland-Debord, C., Bureau, C., Poitou, T., Clavel, M., Perbet, S., Terzi, N., Kouatchet, A., Similowski, T., Demoule, A., Hunfeld, N., Trogrlic, Z., Ladage, S., Osse, R. J., Koch, B., Rietdijk, W., Devlin, J., van der Jagt, M., Picetti, E., Ceccarelli, P., Mensi, F., Malchiodi, L., Risolo, S., Rossi, I., Antonini, M. V., Servadei, F., Caspani, M. L., Roquilly, A., Lasocki, S., Seguin, P., Geeraerts, T., Perrigault, P. F., Dahyot-Fizelier, C., Paugam-Burtz, C., Cook, F., Cinotti, R., dit Latte, D. Demeure, Mahe, P. J., Fortuit, C., Feuillet, F., Asehnoune, K., Marzorati, C., Spina, S., Scaravilli, V., Vargiolu, A., Riva, M., Giussani, C., Sganzerla, E., Citerio, G., Barbadillo, S., de Molina, F. J. González, Álvarez-Lerma, F., Rodríguez, A., Zakharkina, T., Martin-Loeches, I., Matamoros, S., Povoa, P., Torres, A., Kastelijn, J., Hofstra, J. J., de Jong, M., Schultz, M., Sterk, P., Artigas, A., Bos, L. J., Moreau, A. S., Martin-Loeches, I., Povoa, P., Salluh, J., Rodriguez, A., Nseir, S., de Jong, E., van Oers, J. A., Beishuizen, A., Girbes, A. R. J., Nijsten, M. W. N., de Lange, D. W., Bonvicini, D., Labate, D., Benacchio, L., Olivieri, A., Pizzirani, E., Lopez-Delgado, J. C., Gonzalez-Romero, M., Fuentes-Mila, V., Berbel-Franco, D., Romera-Peregrina, I., Martinez-Pascual, A., Perez-Sanchez, J., Abellan-Lencina, R., Ávila-Espinoza, R. E., Moreno-Gonzalez, G., Sbraga, F., Griffiths, S., Grocott, M. P. W., Creagh-Brown, B., Doyle, J., Wilkerson, P., Soon, Y., Huddart, S., Dickinson, M., Riga, A., Zuleika, A., Miyamoto, K., Kawazoe, Y., Morimoto, T., Yamamoto, T., Fuke, A., Hashimoto, A., Koami, H., Beppu, S., Katayama, Y., Ito, M., Ohta, Y., Yamamura, H., Rygård, S. L., Holst, L B., Wetterslev, J., Johansson, P. I., Perner, A., Soliman, I. W., de Lange, D. W., van Dijk, D., van Delden, J. J. M., Cremer, O. L., Slooter, A. J. C., Peelen, L. M., McWilliams, D., Snelson, C., Neves, A. Das, Loudet, C. I., Busico, M., Vazquez, D., Villalba, D., Veronesi, M., Lischinsky, A., López, F. J. L., Mori, L. Benito, Plotnikow, G., Díaz, A., Giannasi, S., Hernandez, R., Krzisnik, L., Cecotti, C., Viola, L., Lopez, R., Sottile, J. P., Benavent, G., Estenssoro, E., Chen, C. M., Lai, C. C., Cheng, K. C., Chou, W., Chan, K. S., Roeker, L. E., Horkan, C. M., Gibbons, F. K., Christopher, K. B., Weijs, P. J. M., Mogensen, K. M., Rawn, J. D., Robinson, M. K., Christopher, K. B., Tang, Z., Qiu, C., Ouyang, B., Cai, C., Guan, X., Regueira, T., Cea, L., Carlos, S. Juan, Elisa, B., Puebla, C., Vargas, A., Poulsen, M. K., Thomsen, L. P., Kjærgaard, S., Rees, S. E., Karbing, D. S., Wollersheim, T., Frank, S., Müller, M. C., Carbon, N. M., Skrypnikov, V., Pickerodt, P. A., Falk, R., Mahlau, A., Weber-Carstens, S., Lee, A., Inglis, R., Morgan, R., Barker, G., Kamata, K., Abe, T., Saitoh, D., Tokuda, Y., Green, R. S., Butler, M. B., Erdogan, M., Hwa, H. Tae, Gil, L. Jae, Vaquero, R. Hernández, Rodriguez-Ruiz, E., Lago, A. Lopez, Allut, J. L. Garcia, Gestal, A. Estany, Gonzalez, M. A. Garcia, Thomas-Rüddel, D. O., Schwarzkopf, D., Fleischmann, C., Reinhart, K., Suwanpasu, S., Sattayasomboon, Y., Filho, N. M. Filgueiras, Oliveira, J. C. A., Ballalai, C. S., De Lucia, C. V., Araponga, G. P., Veiga, L. N., Silva, C. S., Garrido, M. E., Ramos, B. B., Ricaldi, E. F., Gomes, S. S., Gemmell, L., MacKay, A., Wright, C., Docking, R. 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W., Nashan, B., Sterneck, M., Faenza, S., Siniscalchi, A., Pierucci, E., Mancini, E., Ricci, D., Gemelli, C., Cuoghi, A., Magnani, S., Atti, M., Sotos, F., Cánovas, J., López, A., Burruezo, A., Torres, D., Herrera-Gutierrez, M. E., Barrueco-Francioni, J., Arias-Verdú, D., Lozano-Saez, R., Quesada-Garcia, G., Seller-Pérez, G., Figueiredo, A., Anzola, Y., Pereira, R., Bento, L., Arias-Verdú, D., Lai, M., Deiana, M., Barrueco-Francioni, J., Herrera-Gutierrez, M. E., Seller-Perez, G., Vardas, K., Ilia, S., Sertedaki, A., Charmadari, E., Stratakis, C. A., Briassouli, E., Goukos, D., Psarra, K., Botoula, E., Tsagarakis, S., Mageira, E., Routsi, C., Nanas, S., Briassoulis, G., Boscolo, A., Bertini, D., Campello, E., Lucchetta, V., Piasentini, E., Radu, C. M., Manesso, L., Simioni, P., Ori, C., Su, H., Lam, Y. M., Willis, K., Pullar, V., Hubner, R. P., Tsang, J. L., de Guadiana-Romualdo, L. García, Rebollo-Acebes, S., Esteban-Torrella, P., Jiménez-Sánchez, R., Jiménez-Santos, E., Ortín-Freire, A., Hernando-Holgado, A., Albaladejo-Otón, M. D., Coelho, L., Rabello, L., Salluh, J., Martin-Loeches, I., Rodriguez, A., Nseir, S., Póvoa, P., Varis, E., Pettilä, V., Poukkanen, M., Jacob, S., Karlsson, S., Perner, A., Takala, J., Wilkman, E., Lundberg, O. H. M., Bergenzaun, L., Rydén, J., Rosenqvist, M., Melander, O., Chew, M. S., Rodriguez-Ruiz, E., Vaquero, R. Hernández, Lago, A. Lopez, Allut, J. L. Garcia, Gestal, A. Estany, Gonzalez, M. A. Garcia, Kishihara, Y., Yasuda, H., Rebollo, S., de Guadiana-Romualdo, L. García, Jimenez, R., Torrella, P. Esteban, Fernandez, A., Sanchez, S., Ortin, A., Bassi, G. Li, Prats, R. Guillamat, Artigas, A., Aguilera, E., Marti, D., Ranzani, O. T., Rigol, M., Fernandez, L., Ferrer, M., Martin-Loeches, I., Torres, A., Lanziotti, V. S., Póvoa, P., Pulcheri, L., Ribeiro, M. O., Barbosa, A. P., e Silva, J. R. Lapa, Soares, M., Salluh, J. I. F., Garcia, I. Palacios, Martin, A. Diaz, Marqués, M. Gil, Moreno, A. Puppo, Pizarraya, A. Gutierrez, Diaz, J. Pachón, Ibañez, M. Pachón, Smani, Y., Connell, M. Mc, Zhang, L. A., Parker, R. S., Banerjee, I., Clermont, G., Norberg, E., Oras, J., Cuisinier, A., Maufrais, C., Payen, J. F., Nottin, S., Walther, G., Bouzat, P., Arib, S., Bilotta, F., Badenes, R., Rubulotta, F., Mirek, S., Crippa, I. A., Monfort, B., Stazi, E., Roig, A. Lozano, Creteur, J., Taccone, F. S., Magnoni, S., Marando, M., Pifferi, S., Conte, V., Ortolano, F., Carbonara, M., Bertani, G., Scola, E., Cadioli, M., Triulzi, F., Colombo, A., Stocchetti, N., Rotzel, H. B., Lázaro, A. Serrano, Prada, D. Aguillón, Guimillo, M. Rodriguez, Piqueras, C. Sanchís, Guia, J. Romero, Simon, M. García, Arizmendi, A. Mesejo, Carratalá, A., El Maraghi, S., Yehia, A., Bakry, M., Shoman, A., Backes, F. N., Bianchin, M. M., Vieira, S. R. R., de Souza, A., Backes, A. N., Klein, C., Kalaiselvan, M. S., Renuka, M. K., Arunkumar, A. S., Lozano, A., Lheureux, O., Badenes, R., Vincent, J. L., Creteur, J., Taccone, F. S., Gallaher, C., Cattlin, S., Gordon, S., Picard, J., Fontana, V., Bond, O., Nobile, L., Vincent, J. L., Creteur, J., Taccone, F. S., Mrozek, S., Delamarre, L., Capilla, F., Al-Saati, T., Fourcade, O., Geeraerts, T., Dominguez-Berrot, A. M., Gonzalez-Vaquero, M., Vallejo-Pascual, M. E., Gupta, D., Ivory, B. D., Chopra, M., McCarthy, J., Felderhof, C. L., MacNeil, C., Rubulotta, F., Waldauf, P., Maggiorini, M., Duska, F., Fumis, R. R. L., Junior, J. M. Vieira, Amarante, G., Skorko, A., Sanders, S., Aron, J., Kroll, R. J., Redfearn, C., Krishnan, P., Khalil, J. E., Kovari, F., Kongpolprom, N., Gulia, V., Lourenço, E., Melão, L., Duro, C., Baptista, G., Alves, A., Arminda, B., Rodrigues, M., Marreiros, A., Granja, C., Hayward, J., Baldwin, F., Gray, R., Katinakis, P. A., Stijf, M., Ten Kleij, M., Jansen-Frederiks, M., Broek, R., de Bruijne, M., Spronk, P. E., Sinha, K., Luney, M., Palmer, K., Keating, L., Abu-Habsa, M., Bahl, R., Baskaralingam, N., Ahmad, A., Kanapeckaite, L., Bhatti, P., Glace, S., Jeyabraba, S., Lewis, H. F., Kostopoulos, A., Raja, M., West, A., Ely, A., Turkoglu, L. M., Zolfaghari, P., Baptista, J. P., Marques, M. P., Martins, P., Pimentel, J., Gupta, D., Su, Y. C., Villacres, S., Stone, M. E., Parsikia, A., Medar, S., O’Dea, K. P., Porter, J., Tirlapur, N., Jonathan, J. M., Singh, S., Takata, M., Abu-Habsa, M., Ahmad, A., McWhirter, E., Lyon, R., Hariz, M. L., Azmi, E., Alkhan, J., Honeybul, S., Movsisyan, V., Petrikov, S., Marutyan, Z., Aliev, I., Evdokimov, A., Antonucci, E., Merz, T., Hartmann, C., Pelosi, P., Calzia, E., Radermacher, P., Nußbaum, B., Hartmann, C., Huber-Lang, M., Gröger, M., Radermacher, P., Nußbaum, B., Nußbaum, B., Antonucci, E., Calzia, E., Pelosi, P., Radermacher, P., Hartmann, C., Svoren-Jabalera, E., Davenport, E. E., Humburg, P., Knight, J., Hinds, C. J., Jun, I. J., Kim, W. J., Lee, E. H., Besch, G., Perrotti, A., Puyraveau, M., Carteron, L., Baltres, M., Samain, E., Chocron, S., Pili-Floury, S., Plata-Menchaca, E. P., Sabater-Riera, J., Estruch, M., Boza, E., Sbraga, F., Toscana-Fernández, J., Bruguera-Pellicer, E., Ordoñez-Llanos, J., Pérez-Fernández, X. L., Cavaleiro, P., Tralhão, A., Arrigo, M., Lopes, J.-P., Lebrun, M., Cholley, B., PerezVela, J. L., MarinMateos, H., Rivera, J. J. Jimenez, Llorente, M. A. Alcala, De Marcos, B. Gonzalez, Fernandez, F. J. Gonzalez, Laborda, C. Garcia, Zamora, D. Fernandez, Delgado, J. C. Lopez, Imperiali, C., Berbel-Franco, D., Dastis, M., Moreno-Gonzalez, G., Perez-Sanchez, J., Romera-Peregrina, I., Abellan-Lencina, R., Martinez-Pascual, A., Fuentes-Mila, V., Gonzalez-Romero, M., Górka, J., Górka, K., Iwaniec, T., Frołow, M., Polok, K., Fronczek, J., Kózka, M., Musiał, J., Szczeklik, W., Pérez, A. González, Ordoñez, P. Florez, Giribet, A., Cuervo, M. A. Alonso, Cuervo, R. Alonso, Esteban, M. A. Rodriguez, Fraile, L. Iglesias, Mittelbrum, C. Ponte, Albaiceta, G. Muñiz, Ampatzidou, F., Sileli, M., Kehagioglou, G., Madesis, A., Karaiskos, T., Moursia, C., Maleoglou, H., Leleki, K., Drossos, G., Uz, Z., Ince, Y., Papatella, R., Bulent, E., Guerci, P., Ince, C., De Mol, B., Vicka, V., Gineityte, D., Ringaitiene, D., Norkiene, I., Sipylaite, J., Möller, C., Fleischmann, C., Thomas-Rueddel, D. O., Vlasakov, V., Rochwerg, B., Theurer, P., Gattinoni, L., Reinhart, K., Hartog, C. S., Pérez, A. González, Al Sibai, J. Zanabili, Camblor, P. Martinez, Fernandez, P. Alvarez, Gala, J. M. García, Guisasola, J. Silba, Albaiceta, G. Muñiz, Tamura, T., Yatabe, T., Miyajima, I., Yamashita, K., Yokoyama, M., Ampatzidou, F., Kehagioglou, G., Dalampini, E., Nastou, M., Baddour, A., Ignatiadis, A., Asteri, T., Drossos, G., Hathorn, K. E., Purtle, S. W., Horkan, C. M., Gibbons, F. K., Christopher, K. B., Viana, M. V., Tonietto, T. A., Gross, L. A., Costa, V. L., Tavares, A. L. J., Lisboa, B. O., Moraes, R. B., Vieira, S. R., Viana, L. V., Azevedo, M. J., Ceniccola, G. D., Pequeno, R. S. F., Holanda, T. P., Mendonça, V. S., Araújo, W. M. C., Carvalho, L. S. F., Segaran, E., Vickers, L., Brinchmann, K., Wignall, I., Rubulotta, F., De Brito-Ashurst, I., del Olmo, R., Esteban, M. J., Vaquerizo, C., Carreño, R., Gálvez, V., Kaminsky, G., Nieto, B., Fuentes, M., De la Torre, M. A., Torres, E., Alonso, A., Velayos, C., Saldaña, T., Escribá, A., GRIP, J., Kölegård, R., Sundblad, P., Rooyackers, O., Naser, Ben, Jaziri, F., Jazia, A. Ben, Barghouth, M., Hentati, O., Skouri, W., El Euch, M., Mahfoudhi, M., Turki, S., Abdelghni, K. Ben, Abdallah, Ben, Maha, B. N. M., Cánovas, J., Sotos, F., López, A., Lorente, M., Burruezo, A., Torres, D., Polok, K., Włudarczyk, A., Górka, J., Hałek, A., Musiał, J., Szczeklik, W., Jazia, A. Ben, Jaziri, F., Bargouth, M., Bennasr, M., Turki, S., Abdelghani, K. Ben, Abdallah, T. Ben, de Grooth, H. J., Geenen, I. L., Parienti, J. J., Straaten, H. M. Oudemans-van, Shum, H. P., King, H. S., Chan, K. C., Yan, W. W., Londoño, J. Gonzalez, Cardenas, C. Lorencio, Pedrosa, M. Morales, Gubianas, C. Murcia, Bertolin, C. Fuster, Batllori, N. Vila, Sirvent, J. M., Wykes, K., Jack, J., Morgan, P., Mukhopadhyay, A., Chan, H. Y., Kowitlawakul, Y., Remani, D., Leong, C. S. F., Henry, C. J., Puthucheary, Z. A., Mendsaikhan, N., Begzjav, T., Lundeg, G., Dünser, M., Espinoza, E. D. Valenzuela, Welsh, S. P., Motta, M. F., Guerra, E., Zerpa, M. C. l., Zechner, F., Furche, M., Berdaguer, F., Birri, P. N. Rubatto, Risso-Vazquez, A., Dubin, A., Masevicius, F. D., Greaney, D., Magee, A., Fitzpatrick, G., Lugo-Cob, R. G., Sánchez-Hurtado, L. A., Arvizu-Tachiquín, P. C., Tejeda-Huezo, B. C., Cano-Oviedo, A. A., Baltazar-Torres, J. A., Aydogan, M. S., Togal, T., Taha, A., Chai, H. Z., Kam, C., Razali, S. S. Yang, Sivasamy, V., Kuan, L. Y., Poulose, V., Morales, M. A. Lopez, Castro, S., Pires, T., Melão, L., Krystopchuk, A., Pereira, I., Granja, C., Taniguchi, L. U., Pires, E. M. C., Vieira, Jr, J. M., Azevedo, L. C. P., Nurses of the Central and General ICUs of Shiraz Namazi Hospital, Sedation an Delirium Group Hospital Universitari de Bellvitge, SPACeR group (Surrey Peri-operative, Anaesthesia and Critical Care Collaborative Research Group), for the PRoVENT investigators and the PROVE Network, SEMICYUC/GETGAG Working Group, TAVeM study group, POPC-CB investigators, DESIRE (DExmedetomidine for Sepsis in ICU Randomized Evaluation) Trial Investigators, GEMINI, Bioethics work group of SEMICYUC, The FINNAKI Study Group, Queen Square Neuroanaesthesia and Neurocritical Care Resreach Group, Renal Transplantation HUVR, GEMINI, EDISVAL Group, EDISVAL Group, PLUG Working group, TAVeM study Group, The FINNAKI Study Group, on behalf of Department of Professional Development, ESICM, Critical Care Research Group, SIRAKI group, and Grupo ESBAGA

Published
2016
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18. The Impact of Health Professionals' Language on Patient Experience: A Case Study

Author

Katz, NT, Jones, J, Mansfield, L, Gold, M, Katz, NT, Jones, J, Mansfield, L, and Gold, M

Abstract

When people become patients, they become vulnerable to their healthcare system and healthcare clinicians. In this case study, we describe an example of patient distress caused by language overheard in the perioperative environment. Clinicians need to be mindful that the language we use may have a significant impact on patient experience, be it during direct conversation or from conversations overheard. This is an important component of patient-centered care.

Published
2022

19. Implications for sequencing of biologic therapy and choice of second anti-TNF in patients with inflammatory bowel disease: results from the IMmunogenicity to Second Anti-TNF therapy (IMSAT) therapeutic drug monitoring study.

Author

Chanchlani, N., Lin, S., Auth, M.K., Lee, C.L., Robbins, H., Looi, S., Murugesan, S.V., Riley, T., Preston, C., Stephenson, S., Cardozo, W., Sonwalkar, S.A., Allah-Ditta, M., Mansfield, L., Durai, D., Baker, M., London, I., London, E., Gupta, S., Mambro, A. Di, Murphy, A., Gaynor, E., Jones, K.D.J., Claridge, A., Sebastian, S., Ramachandran, S., Selinger, C.P., Borg-Bartolo, S.P., Knight, P., Sprakes, M.B., Burton, J., Kane, P., Lupton, S., Fletcher, A., Gaya, D.R., Colbert, R., Seenan, J.P., Macdonald, J., Lynch, L., McLachlan, I., Shields, S., Hansen, R., Gervais, L., Jere, M., Akhtar, M., Black, K., Henderson, P., Russell, R.K., Lees, C.W., Derikx, L.A.A.P., Lockett, M., Betteridge, F., Silva, Aminda de, Hussenbux, A., Beckly, J., Bendall, O., Hart, J.W., Thomas, A., Hamilton, B., Gordon, C., Chee, D., McDonald, T.J., Nice, R., Parkinson, M., Gardner-Thorpe, H., Butterworth, J.R., Javed, A., Al-Shakhshir, S., Yadagiri, R., Maher, S., Pollok, R.C.G., Ng, T., Appiahene, P., Donovan, F., Lok, James, Chandy, R., Jagdish, R., Baig, D., Mahmood, Z., Marsh, L., Moss, A., Abdulgader, A., Kitchin, A., Walker, G.J.A., George, B., Lim, Y.H., Gulliver, J., Bloom, S., Theaker, H., Carlson, S., Cummings, J.R.F., Livingstone, R., Beale, A., Carter, Jodi M., Bell, A., Coulter, A., Snook, J., Stone, H., Kennedy, N.A., Goodhand, J.R., Ahmad, T., Chanchlani, N., Lin, S., Auth, M.K., Lee, C.L., Robbins, H., Looi, S., Murugesan, S.V., Riley, T., Preston, C., Stephenson, S., Cardozo, W., Sonwalkar, S.A., Allah-Ditta, M., Mansfield, L., Durai, D., Baker, M., London, I., London, E., Gupta, S., Mambro, A. Di, Murphy, A., Gaynor, E., Jones, K.D.J., Claridge, A., Sebastian, S., Ramachandran, S., Selinger, C.P., Borg-Bartolo, S.P., Knight, P., Sprakes, M.B., Burton, J., Kane, P., Lupton, S., Fletcher, A., Gaya, D.R., Colbert, R., Seenan, J.P., Macdonald, J., Lynch, L., McLachlan, I., Shields, S., Hansen, R., Gervais, L., Jere, M., Akhtar, M., Black, K., Henderson, P., Russell, R.K., Lees, C.W., Derikx, L.A.A.P., Lockett, M., Betteridge, F., Silva, Aminda de, Hussenbux, A., Beckly, J., Bendall, O., Hart, J.W., Thomas, A., Hamilton, B., Gordon, C., Chee, D., McDonald, T.J., Nice, R., Parkinson, M., Gardner-Thorpe, H., Butterworth, J.R., Javed, A., Al-Shakhshir, S., Yadagiri, R., Maher, S., Pollok, R.C.G., Ng, T., Appiahene, P., Donovan, F., Lok, James, Chandy, R., Jagdish, R., Baig, D., Mahmood, Z., Marsh, L., Moss, A., Abdulgader, A., Kitchin, A., Walker, G.J.A., George, B., Lim, Y.H., Gulliver, J., Bloom, S., Theaker, H., Carlson, S., Cummings, J.R.F., Livingstone, R., Beale, A., Carter, Jodi M., Bell, A., Coulter, A., Snook, J., Stone, H., Kennedy, N.A., Goodhand, J.R., and Ahmad, T.

Abstract

Item does not contain fulltext, BACKGROUND: Anti-drug antibodies are associated with treatment failure to anti-TNF agents in patients with inflammatory bowel disease (IBD). AIM: To assess whether immunogenicity to a patient's first anti-TNF agent would be associated with immunogenicity to the second, irrespective of drug sequence METHODS: We conducted a UK-wide, multicentre, retrospective cohort study to report rates of immunogenicity and treatment failure of second anti-TNF therapies in 1058 patients with IBD who underwent therapeutic drug monitoring for both infliximab and adalimumab. The primary outcome was immunogenicity to the second anti-TNF agent, defined at any timepoint as an anti-TNF antibody concentration ≥9 AU/ml for infliximab and ≥6 AU/ml for adalimumab. RESULTS: In patients treated with infliximab and then adalimumab, those who developed antibodies to infliximab were more likely to develop antibodies to adalimumab, than patients who did not develop antibodies to infliximab (OR 1.99, 95%CI 1.27-3.20, p = 0.002). Similarly, in patients treated with adalimumab and then infliximab, immunogenicity to adalimumab was associated with subsequent immunogenicity to infliximab (OR 2.63, 95%CI 1.46-4.80, p < 0.001). For each 10-fold increase in anti-infliximab and anti-adalimumab antibody concentration, the odds of subsequently developing antibodies to adalimumab and infliximab increased by 1.73 (95% CI 1.38-2.17, p < 0.001) and 1.99 (95%CI 1.34-2.99, p < 0.001), respectively. Patients who developed immunogenicity with undetectable drug levels to infliximab were more likely to develop immunogenicity with undetectable drug levels to adalimumab (OR 2.37, 95% CI 1.39-4.19, p < 0.001). Commencing an immunomodulator at the time of switching to the second anti-TNF was associated with improved drug persistence in patients with immunogenic, but not pharmacodynamic failure. CONCLUSION: Irrespective of drug sequence, immunogenicity to the first anti-TNF agent was associated with immunogenicity to the seco

Published
2022

20. Absolute photoluminescence intensity in thin film solar cells.

Author

Swartz, C. H., Paul, S., Mansfield, L. M., and Holtz, M. W.

Subjects
PHOTOLUMINESCENCE measurement, LUMINESCENCE, OPEN-circuit voltage, PHOTOLUMINESCENCE, THIN films, SOLAR cells
Abstract

A calculation is presented for the direct conversion of a measured luminescence signal to the implied open circuit voltage. The effects of re-absorption, spectral dependence, and interference with front and back interfaces are all included, so long as the optical properties of the structure are known. The method is validated through a comparison of the terminal open-circuit voltage with the photoluminescence intensity of Cu(In,Ga)Se2 solar cells, each as a function of illumination intensity. [ABSTRACT FROM AUTHOR]

Published
2019
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24. Social capital in participatory arts for wellbeing : Findings from a systematic review of qualitative research

Author

Mansfield, L, Daykin, N, Victor, C, Meads, C, Tomlinson, A, Gray, K, Golding, A, Tampere University, and Communication Sciences

Subjects
5141 Sociology
Abstract

Background Social capital is often cited as shaping impacts of participatory arts, although the concept has not been systematically mapped in arts, health and wellbeing contexts. In wider health inequalities research, complex, differential, and sometimes negative impacts of social capital have been recognised. Methods This paper maps of social capital concepts in qualitative research as part of the UK What Works for Wellbeing evidence review programme on culture, sport and wellbeing. Results Studies often cite positive impacts of bonding and, to a lesser extent, bridging social capital. However, reported challenges suggest the need for a critical approach. Forms of linking social capital, such as reframing and political engagement to address social divisions, are less often cited but may be important in participatory arts and wellbeing. Conclusions Future research should further specify dimensions of social capital as well as their nuanced effects in arts, and wellbeing contexts. publishedVersion

Published
2020

25. Do toxic Pseudo-nitzschia species pose a threat to aquaculture in the southern Benguela eastern boundary upwelling system?

Author

Pitcher, Grant C., Cembella, Allan, Krock, Bernd, Macey, BM, Mansfield, L., Pitcher, Grant C., Cembella, Allan, Krock, Bernd, Macey, BM, and Mansfield, L.

Abstract

The productive but highly exposed coastline of the southern Benguela eastern boundary upwelling system offers limited natural environment for aquaculture. Saldanha Bay located on the west coast of South Africa is one of the few embayments on the coastline that provides a productive and relatively sheltered environment suitable for the cultivation of shellfish. Consequently, bivalve culture in South Africa is centered in Saldanha Bay and is presently targeted for expansion. Pseudo-nitzschia blooms including toxin-producing species are shown to contribute significantly to the phytoplankton of Saldanha Bay specifically in spring and summer. Their dominance at this time of the year, when upwelling is strongest, fits the ecological profile of Pseudo-nitzschia occurring during periods of high turbulence and nutrients. Multiple Pseudo-nitzschia blooms were sampled under varying environmental conditions and the strength of the relationship between Pseudo-nitzschia cell abundance and particulate domoic acid (pDA) content, reflecting bloom toxicity, varied greatly. This variability is the result of the combined influence of species and strain composition of the Pseudo-nitzschia assemblage and the effect of environmental conditions on toxin production. Elevated levels of pDA were associated with higher concentrations of cells of the P. seriata complex differentiated by frustule width (>3 µm). P. australis was identified as a toxin-producing species and a prominent member of the P. seriata complex. Low DA levels in shellfish in Saldanha Bay are considered a function of low cellular domoic acid (cDA). Silicate limitation has emerged as an important factor inducing DA production in Pseudo-nitzschia species. The high ratio of silicate to nitrate in Saldanha Bay provides a plausible explanation for the low toxin content of Pseudo-nitzschia blooms in the bay and the consequent low risk posed by these blooms to the aquaculture sector.

Published
2020

29. Community Sport and the Politics of Aging: Co-design and Partnership Approaches to Understanding the Embodied Experiences of Low-Income Older People

Author

Mansfield, L, Kay, T, Anokye, N, and Fox-Rushby, J

Subjects
Community Sport, coproduction, aging, lcsh:HM401-1281, physical activity, General Social Sciences, Ageing, Embodiment, community sport, lcsh:Sociology (General), Sociology, Coproduction, Original Research, embodiment
Abstract

© 2019 Mansfield, Kay, Anokye and Fox-Rushby. The promotion of physical activity for older people is dominated by biomedically informed polices emphasising the prescription of exercise as medicine and a universal approach to the promotion of active ageing in later life. Yet, more recent research recognises that being physically active in later life is complex and contested, shaped by the intersections of biological, psychological and sociological experiences, and requires differentiated responses that address this complexity. There is a disconnect between research, policy and the physical activity experiences of older people which leads to over-generalised policy and practice in the promotion and delivery of community sport to older people. This paper presents findings from a complex community sport project employing a coproduction framework with low income older age people. Participatory community approaches including focus group discussions, and extended observations and informal conversations throughout the project develop understanding of the complexities of ageing and community sport engagement among older people with limited income. Three themes are identified and discussed: (1) lived experience, ageing bodies and the changing dynamics of involvement in sport and exercise in the life course, (2) embodying ageing - moving beyond practical barriers for understanding ageing, lived experience and being physically active, and (3) corporeal pleasures of older sporting bodies. The paper concludes that there is a need to explore the significance of locally specific public knowledge from older people which directly addresses the complexity and inequalities of individuals’ everyday lives in their communities; lived experiences likely to impact on preferences for, engagement in, and enjoyment of physical activity. Sport England’s Get Healthy, Get Active for the Health and Sport Engagement Project

Published
2019
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30. Royal Museums Greenwich - Refugee Week Report

Author

Mansfield, L and Smith, R

Abstract

Royal Museums Greenwich (RMG) worked with Brunel University London to conduct a qualitative evaluation of RMGs Refugee Week Programme 2019. The aim of this evaluation was to enhance understandings of how to engage refugee and asylum-seeking populations in wellbeing programming at the RMG. Participant observation was conducted at the National Maritime Museum during Refugee Week on the 20th and 22nd of June. This report is split into four sections: Section 1 provides a brief overview of the background and the project, Section 2 describes the methods used, Section 3 outlines the research findings, and Section 4 presents the conclusions and recommendations.

Published
2019

33. What works for wellbeing? A systematic review of wellbeing outcomes for music and singing in adults

Author

Daykin, N, Mansfield, L, Julier, G, Tomlinson, A, Meads, C, Payne, A, Grigsby-Duffy, L, Lane, J, D'innocenzo, G, Burnett, A, Kay, T, Dolan, P, Testoni, S, and Victor, C

Subjects
Adult, singing, H Social Sciences (General), Health Status, M Music, humanities, older people, Mental Health, wellbeing, systematic review, RA0421 Public health. Hygiene. Preventive Medicine, depression, Quality of Life, Humans, music
Abstract

IMS:\ud The role of arts and music in supporting subjective wellbeing (SWB) is increasingly recognised. Robust evidence is needed to support policy and practice. This article reports on the first of four reviews of Culture, Sport and Wellbeing (CSW) commissioned by the Economic and Social Research Council (ESRC)-funded What Works Centre for Wellbeing ( https://whatworkswellbeing.org/ ).\ud OBJECTIVE:\ud To identify SWB outcomes for music and singing in adults.\ud METHODS:\ud Comprehensive literature searches were conducted in PsychInfo, Medline, ERIC, Arts and Humanities, Social Science and Science Citation Indexes, Scopus, PILOTS and CINAHL databases. From 5,397 records identified, 61 relevant records were assessed using GRADE and CERQual schema.\ud RESULTS:\ud A wide range of wellbeing measures was used, with no consistency in how SWB was measured across the studies. A wide range of activities was reported, most commonly music listening and regular group singing. Music has been associated with reduced anxiety in young adults, enhanced mood and purpose in adults and mental wellbeing, quality of life, self-awareness and coping in people with diagnosed health conditions. Music and singing have been shown to be effective in enhancing morale and reducing risk of depression in older people. Few studies address SWB in people with dementia. While there are a few studies of music with marginalised communities, participants in community choirs tend to be female, white and relatively well educated. Research challenges include recruiting participants with baseline wellbeing scores that are low enough to record any significant or noteworthy change following a music or singing intervention.\ud CONCLUSIONS:\ud There is reliable evidence for positive effects of music and singing on wellbeing in adults. There remains a need for research with sub-groups who are at greater risk of lower levels of wellbeing, and on the processes by which wellbeing outcomes are, or are not, achieved.

Published
2018

34. Defining and Measuring Subjective Wellbeing for Sport Policy

Author

Testoni, S, Mansfield, L, and Dolan, P

Abstract

This paper makes the case for assessing the value of sport based on people’s reports of subjective wellbeing (SWB), i.e. how they feel. We compare SWB to conventional definitions of wellbeing. We discuss how SWB is measured, distinguishing between evaluations (e.g., life-satisfaction) and experiences (feelings held moment to moment). We then consider evidence on the impact of sport on both evaluations and experiences of SWB, showing that the two give rise to different insights. We argue that measures that focus on how people feel as they go about their lives are better suited to accounting for the value of sport. We conclude by encouraging the measurement of experiences of SWB in sport policy.

Published
2018

40. Intracerebral hemorrhage in ICU: is it worth treating?

Author

Sivakumar, S, Taccone, F, Desai, K, Lazaridis, C, Skarzynski, M, Sekhon, M, Henderson, W, Griesdale, D, Chapple, L, Deane, A, Williams, L, Strickland, R, Lange, K, Heyland, D, Chapman, M, Rowland, M, Garry, P, Westbrook, J, Corkill, R, Antoniades, C, Pattinson, K, Fatania, G, Strong, A, Myers, R, Jermaine, C, Robertson, C, Rusin, C, Hofmeijer, J, Sondag, L, Tjepkema Cloostermans, M, Beishuizen, A, Bosch, F, van Putten, M, Carteron, L, Patet, C, Solari, D, Oddo, M, Ali, M, Dias, C, Almeida, R, Vaz Ferreira, A, Silva, J, Monteiro, E, Cerejo, A, Rocha, A, Elsayed, A, Abougabal, A, Beshey, B, Alzahaby, K, Pozzebon, S, Ortiz, A, Cristallini, S, Lheureux, O, Brasseur, A, Vincent, J, Creteur, J, Hravnak, M, Yousef, K, Chang, Y, Crago, E, Friedlander, R, Abdelmonem, S, Tahon, S, Helmy, T, Meligy, H, Puig, F, Dunn Siegrist, I, Pugin, J, Gupta, S, Govil, D, Srinivasan, S, Patel, S, N, J, Gupta, A, Tomar, D, Shafi, M, Harne, R, Arora, D, Talwar, N, Mazumdar, S, Papakrivou, E, Makris, D, Manoulakas, E, Tsolaki, B, Karadodas, B, Zakynthinos, E, Garcia, I, Martin, A, Encinares, V, Ibañez, M, Montero, J, Labrador, G, Cangueiro, T, Poulose, V, Koh, J, Kam, J, Yeter, H, Kara, A, Aktepe, O, Topeli, A, Tsolakoglou, I, Intas, G, Stergiannis, P, Kolaros, A, Chalari, E, Athanasiadou, E, Martika, A, Fildisis, G, Faivre, V, Mengelle, C, Favier, B, Payen, D, Poppe, A, Winkler, M, Mudersbach, E, Schreiber, J, Wruck, M, Schwedhelm, E, Kluge, S, Zöllner, C, Tavladaki, T, Spanaki, A, Dimitriou, H, Kondili, E, Choulaki, C, Meleti, E, Kafetzopoulos, D, Georgopoulos, D, Briassoulis, G, la Torre, A, de la Torre Prados, M, Tsvetanova Spasova, T, Nuevo Ortega, P, Rueda Molina, C, Fernández Porcel, A, Camara Sola, E, Salido Díaz, L, García Alcántara, A, Meleti, D, Suberviola, B, Riera, J, Rellan, L, Sanchez, M, Robles, J, Lopez, E, Vicente, R, Miñambres, E, Santibañez, M, Le Guen, M, Moore, J, Mason, N, Windpassinger, M, Plattner, O, Mascha, E, Sessler, D, Research, O, Melia, U, Fontanet, J, van den Berg, J, Struys, M, Vereecke, H, Jensen, E, Rood, P, van de Schoor, F, van Tertholen, K, Pickkers, P, van den Boogaard, M, Beardow, Z, Redhead, H, Paramasivam, K, Numan, T, Kamper, A, Peelen, L, Zeman, P, Slooter, A, van Ewijk, C, Jacobs, G, Girbes, A, Myatra, S, Harish, M, Prabu, N, Siddiqui, S, Kulkarni, A, Divatia, J, Murbach, L, Leite, M, Osaku, E, Costa, C, Pelenz, M, Neitzke, N, Moraes, M, Jaskowiak, J, Silva, M, Zaponi, R, Abentroth, L, Ogasawara, S, Jorge, A, Duarte, P, Hernández Sánchez, N, Sánchez Hurtado, L, García Guillen, F, Ñamendys Silva, S, Maghsoudi, B, Emami, M, Khosravi, M, Zand, F, Tabatabaie, H, Masjedi, M, Sabetiyan, G, Mokri, A, Troubleyn, J, Diltoer, M, Jacobs, R, Nguyen, D, De Waele, E, De Regt, J, Honoré, P, Van Gorp, V, Spapen, H, Contreras, R, Toapanta, N, Moreno, G, Sabater, J, Torrado, H, Gonzalez, M, Marin, M, Farigola, E, Gonzalez, A, Fernandez, J, Vera, A, Gisbert, X, Juliá, C, Uya, J, Corral, L, Elias Jones, I, Gemmell, L, Mackay, A, Randall, 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Trauner, M, Pischke, S, Fischer, L, Thaiss, F, Koch, M, Bangert, K, Lohse, A, Nashan, B, Sterneck, M, Faenza, S, Siniscalchi, A, Pierucci, E, Mancini, E, Ricci, D, Gemelli, C, Cuoghi, A, Magnani, S, Atti, M, Sotos, F, Cánovas, J, López, A, Burruezo, A, Torres, D, Herrera Gutierrez, M, Barrueco Francioni, J, Arias Verdú, D, Lozano Saez, R, Quesada Garcia, G, Seller Pérez, G, Figueiredo, A, Anzola, Y, Pereira, R, Bento, L, Lai, M, Deiana, M, Seller Perez, G, Vardas, K, Ilia, S, Sertedaki, A, Charmadari, E, Stratakis, C, Briassouli, E, Goukos, D, Psarra, K, Botoula, E, Tsagarakis, S, Mageira, E, Routsi, C, Nanas, S, Campello, E, Radu, C, Su, H, Lam, Y, Willis, K, Pullar, V, Hubner, R, Tsang, J, de Guadiana Romualdo, L, Rebollo Acebes, S, Esteban Torrella, P, Jiménez Sánchez, R, Jiménez Santos, E, Ortín Freire, A, Hernando Holgado, A, Albaladejo Otón, M, Coelho, L, Rabello, L, Póvoa, P, Varis, E, Poukkanen, M, Jacob, S, Takala, J, Wilkman, E, Lundberg, O, Bergenzaun, L, Rydén, J, Rosenqvist, M, Melander, O, Chew, M, Kishihara, Y, Yasuda, H, Jimenez, R, Torrella, P, Fernandez, A, Sanchez, S, Ortin, A, Prats, R, Aguilera, E, Marti, D, Fernandez, L, Ferrer, M, Lanziotti, V, Pulcheri, L, Ribeiro, M, Barbosa, A, E. Silva, J, Soares, M, Marqués, M, Moreno, A, Pizarraya, A, Smani, Y, Connell, M, Zhang, L, Parker, R, Banerjee, I, Clermont, G, Norberg, E, Oras, J, Cuisinier, A, Maufrais, C, Payen, J, Nottin, S, Walther, G, Arib, S, Bilotta, F, Badenes, R, Rubulotta, F, Mirek, S, Monfort, B, Stazi, E, Roig, A, Magnoni, S, Marando, M, Pifferi, S, Conte, V, Ortolano, F, Carbonara, M, Bertani, G, Scola, E, Cadioli, M, Triulzi, F, Colombo, A, Stocchetti, N, Rotzel, H, Lázaro, A, Prada, D, Guimillo, M, Piqueras, C, Guia, J, Simon, M, Arizmendi, A, Carratalá, A, El Maraghi, S, Yehia, A, Bakry, M, Shoman, A, Backes, F, Bianchin, M, Vieira, S, de Souza, A, Backes, A, Klein, C, Arunkumar, A, Lozano, A, Gallaher, C, Cattlin, S, Gordon, S, Picard, J, Fontana, V, Bond, O, Nobile, L, Mrozek, S, Delamarre, L, Capilla, F, Al Saati, T, Fourcade, O, Dominguez Berrot, A, Gonzalez Vaquero, M, Vallejo Pascual, M, Gupta, D, Ivory, B, Chopra, M, Mccarthy, J, Felderhof, C, Macneil, C, Maggiorini, M, Duska, F, Fumis, R, Junior, J, Amarante, G, Skorko, A, Sanders, S, Aron, J, Kroll, R, Redfearn, C, Krishnan, P, Khalil, J, Kongpolprom, N, Gulia, V, Lourenço, E, Duro, C, Baptista, G, Alves, A, Arminda, B, Rodrigues, M, Hayward, J, Baldwin, F, Gray, R, Katinakis, P, Stijf, M, Ten Kleij, M, Jansen Frederiks, M, Broek, R, de Bruijne, M, Spronk, P, Sinha, K, Luney, M, Palmer, K, Keating, L, Abu Habsa, M, Bahl, R, Baskaralingam, N, Ahmad, A, Kanapeckaite, L, Bhatti, P, Glace, S, Jeyabraba, S, Lewis, H, Kostopoulos, A, Raja, M, West, A, Ely, A, Turkoglu, L, Zolfaghari, P, Baptista, J, Marques, M, Martins, P, Pimentel, J, Su, Y, Villacres, S, Stone, M, Parsikia, A, Medar, S, O'Dea, K, Porter, J, Tirlapur, N, Jonathan, J, Singh, S, Takata, M, Mcwhirter, E, Lyon, R, Hariz, M, Azmi, E, Alkhan, J, Movsisyan, V, Petrikov, S, Marutyan, Z, Aliev, I, Evdokimov, A, Antonucci, E, Merz, T, Hartmann, C, Calzia, E, Radermacher, P, Nußbaum, B, Huber Lang, M, Gröger, M, Svoren Jabalera, E, Davenport, E, Humburg, P, Knight, J, Hinds, C, Jun, I, Kim, W, Besch, G, Perrotti, A, Puyraveau, M, Baltres, M, Samain, E, Chocron, S, Pili Floury, S, Plata Menchaca, E, Sabater Riera, J, Estruch, M, Boza, E, Toscana Fernández, J, Bruguera Pellicer, E, Ordoñez Llanos, J, Pérez Fernández, X, Cavaleiro, P, Tralhão, A, Arrigo, M, Lopes, J, Lebrun, M, Cholley, B, Perezvela, J, Marinmateos, H, Rivera, J, Llorente, M, De Marcos, B, Fernandez, F, Laborda, C, Zamora, D, Delgado, J, Imperiali, C, Dastis, M, Górka, J, Górka, K, Iwaniec, T, Frołow, M, Polok, K, Fronczek, J, Kózka, M, Musiał, J, Szczeklik, W, Sileli, M, Moursia, C, Maleoglou, H, Leleki, K, Uz, Z, Ince, Y, Papatella, R, Bulent, E, De Mol, B, Vicka, V, Gineityte, D, Ringaitiene, D, Norkiene, I, Sipylaite, J, Möller, C, Thomas Rueddel, D, Vlasakov, V, Rochwerg, B, Theurer, P, Al Sibai, J, Camblor, P, Fernandez, P, Gala, J, Guisasola, J, Tamura, T, Miyajima, I, Yamashita, K, Yokoyama, M, Dalampini, E, Nastou, M, Baddour, A, Ignatiadis, A, Asteri, T, Hathorn, K, Purtle, S, Viana, M, Tonietto, T, Gross, L, Costa, V, Tavares, A, Lisboa, B, Moraes, R, Viana, L, Azevedo, M, Ceniccola, G, Pequeno, R, Holanda, T, Mendonça, V, Araújo, W, Carvalho, L, Segaran, E, Vickers, L, Brinchmann, K, Wignall, I, De Brito Ashurst, I, Del Olmo, R, Vaquerizo, C, Carreño, R, Gálvez, V, Kaminsky, G, Nieto, B, Fuentes, M, De la Torre, M, Torres, E, Alonso, A, Velayos, C, Saldaña, T, Escribá, A, Grip, J, Kölegård, R, Sundblad, P, Rooyackers, O, Naser, B, Jaziri, F, Jazia, A, Barghouth, M, Hentati, O, Skouri, W, El Euch, M, Mahfoudhi, M, Turki, S, Abdelghni, K, Abdallah, B, Maha, B, Lorente, M, Włudarczyk, A, Hałek, A, Bargouth, M, Bennasr, M, Abdelghani, K, Abdallah, T, Geenen, I, Parienti, J, Shum, H, King, H, Yan, W, Londoño, J, Cardenas, C, Pedrosa, M, Gubianas, C, Bertolin, C, Batllori, N, Sirvent, J, Mukhopadhyay, A, Chan, H, Kowitlawakul, Y, Remani, D, Leong, C, Henry, C, Puthucheary, Z, Mendsaikhan, N, Begzjav, T, Lundeg, G, Dünser, M, Welsh, S, Guerra, E, Zerpa, M, Zechner, F, Berdaguer, F, Risso Vazquez, A, Masevicius, F, Greaney, D, Magee, A, Fitzpatrick, G, Lugo Cob, R, Tejeda Huezo, B, Cano Oviedo, A, Aydogan, M, Togal, T, Taha, A, Chai, H, Kam, C, Razali, S, Sivasamy, V, Kuan, L, Morales, M, Pires, T, and Azevedo, L

Subjects
intracerebral haemorrhage in intensive care
Published
2016

41. Adherence to best practice consensus guidelines for implant-based breast reconstruction: Results from the iBRA national practice questionnaire survey.

Author

Mazari F.A.K., Youssef M., Graja T., Huf S., Deol H., Brindle R., Gawne S., Egbeare D., Dash I., Galea M., Laws S., Tayeh S., Parvanta L., Down S., Westbroek D., Roberts J.W., Massey J., Turton P., Achuthan R., Fawzy M., Dickson M., Carmichael A.R., Akingboye A., James R., Kirkpatrick K., Nael E., Vidya R., Thorne A., Rostom M., Depasquale I., Cawthorn S.J., Gangamihardja T., Joglekar S., Smith J., Halka A., MacMillan D., Clark S., Pearce B., Mansfield L., King I., Hazari A., Smith B., Volleamere A.J., Ferguson D., Barnes N., Knight A., MacNeill F., Conway A., Irvine T., Mylavaganam S., Dunne N., Kohlhardt S., Hoo C., Kirk S., Hu J., Ledwidge S., Tang S., Banerjee D., Waheed S., Voynov V., Soumian S., Henderson J., Harvey J., Robertson S., Waters R., Carbone A., Farooq A., Tafazal H., Clarke D., Cocker D., Lai L.M., Winter Beatty J., Barkeji M., Vinayagam R., Mullan M., Osborne C., Baker E., Piper J., Mylvaganam S., Conroy E.J., Williamson P.R., Barnes N.L.P., Cutress R.I., Gardiner M.D., Jain A., Skillman J.M., Thrush S., Whisker L.J., Blazeby J.M., Potter S., Holcombe C., Branford O.A., McEvoy K., Mills N., Teasdale E.M., Tang L., Nguyen D., Johnson R., Muralikrishnan V., Chopra S., Reid A., Benyon S., Murphy C., Soliman F., Lefemine V., Saha S., Ogedegbe K., Olyinka O.S., Dicks J.R., Manoloudakis N., Conroy F., Irwin G., McIntosh S., Michalakis I., Hignett S., Linforth R., Rathinaezhil R., Osman H., Anesti K., Griffiths M., Jacklin R., Waterworth A., Foulkes R., Davies E., Bisarya K., Allan A., Leon-Villapalos J., Azmy I., George S., Fahmy F.S., Hargreaves A., Seward J., Henton J., Collin T., Mallon P., Turner J., Sarakbi W., Athanasiou I., Rogers C., Mazari F.A.K., Youssef M., Graja T., Huf S., Deol H., Brindle R., Gawne S., Egbeare D., Dash I., Galea M., Laws S., Tayeh S., Parvanta L., Down S., Westbroek D., Roberts J.W., Massey J., Turton P., Achuthan R., Fawzy M., Dickson M., Carmichael A.R., Akingboye A., James R., Kirkpatrick K., Nael E., Vidya R., Thorne A., Rostom M., Depasquale I., Cawthorn S.J., Gangamihardja T., Joglekar S., Smith J., Halka A., MacMillan D., Clark S., Pearce B., Mansfield L., King I., Hazari A., Smith B., Volleamere A.J., Ferguson D., Barnes N., Knight A., MacNeill F., Conway A., Irvine T., Mylavaganam S., Dunne N., Kohlhardt S., Hoo C., Kirk S., Hu J., Ledwidge S., Tang S., Banerjee D., Waheed S., Voynov V., Soumian S., Henderson J., Harvey J., Robertson S., Waters R., Carbone A., Farooq A., Tafazal H., Clarke D., Cocker D., Lai L.M., Winter Beatty J., Barkeji M., Vinayagam R., Mullan M., Osborne C., Baker E., Piper J., Mylvaganam S., Conroy E.J., Williamson P.R., Barnes N.L.P., Cutress R.I., Gardiner M.D., Jain A., Skillman J.M., Thrush S., Whisker L.J., Blazeby J.M., Potter S., Holcombe C., Branford O.A., McEvoy K., Mills N., Teasdale E.M., Tang L., Nguyen D., Johnson R., Muralikrishnan V., Chopra S., Reid A., Benyon S., Murphy C., Soliman F., Lefemine V., Saha S., Ogedegbe K., Olyinka O.S., Dicks J.R., Manoloudakis N., Conroy F., Irwin G., McIntosh S., Michalakis I., Hignett S., Linforth R., Rathinaezhil R., Osman H., Anesti K., Griffiths M., Jacklin R., Waterworth A., Foulkes R., Davies E., Bisarya K., Allan A., Leon-Villapalos J., Azmy I., George S., Fahmy F.S., Hargreaves A., Seward J., Henton J., Collin T., Mallon P., Turner J., Sarakbi W., Athanasiou I., and Rogers C.

Abstract

Introduction: The 2008 National Mastectomy and Breast Reconstruction Audit demonstrated marked variation in the practice and outcomes of breast reconstruction in the UK. To standardise practice and improve outcomes for patients, the British professional associations developed best-practice guidelines with specific guidance for newer mesh-assisted implant-based techniques. We explored the degree of uptake of best-practice guidelines within units performing implant-based reconstruction (IBBR) as the first phase of the implant Breast Reconstruction Evaluation (iBRA) study. Method(s): A questionnaire developed by the iBRA Steering Group was completed by trainee and consultant leads at breast and plastic surgical units across the UK. Simple summary statistics were calculated for each survey item to assess compliance with current best-practice guidelines. Result(s): 81 units from 79 NHS Trusts completed the questionnaire. Marked variation was observed in adherence to guidelines, especially those relating to clinical governance and infection prevention strategies. Less than half (n = 28, 47%) of units obtained local clinical governance board approval prior to offering new mesh-based techniques and prospective audit of the clinical, cosmetic and patient-reported outcomes of surgery was infrequent. Most units screened for methicillin-resistant staphylococcus aureus prior to surgery but fewer than 1 in 3 screened for methicillin-sensitive strains. Laminar-flow theatres (recommended for IBBR) were not widely-available with less than 1 in 5 units having regular access. Peri-operative antibiotics were widely-used, but the type and duration were highly-variable. Conclusion(s): The iBRA national practice questionnaire has demonstrated variation in reported practice and adherence to IBBR guidelines. High-quality evidence is urgently required to inform best practice.Copyright © 2018 The Authors

Published
2018

44. Adherence to best practice consensus guidelines for implant-based breast reconstruction: Results from the iBRA national practice questionnaire survey

Author

Mylvaganam, Senthurun, primary, Conroy, Elizabeth J., additional, Williamson, Paula R., additional, Barnes, Nicola L.P., additional, Cutress, Ramsey I., additional, Gardiner, Matthew D., additional, Jain, Abhilash, additional, Skillman, Joanna M., additional, Thrush, Steven, additional, Whisker, Lisa J., additional, Blazeby, Jane M., additional, Potter, Shelley, additional, Holcombe, Christopher, additional, Barnes, N.L.P., additional, Blazeby, J.M., additional, Branford, O.A., additional, Conroy, E.J., additional, Cutress, R.I., additional, Gardiner, M.D., additional, Holcombe, C., additional, Jain, A., additional, McEvoy, K., additional, Mills, N., additional, Mylvaganam, S., additional, Potter, S., additional, Skillman, J.M., additional, Teasdale, E.M., additional, Thrush, S., additional, Whisker, L.J., additional, Williamson, P.R., additional, Tang, L., additional, Nguyen, D., additional, Johnson, R., additional, Muralikrishnan, V., additional, Chopra, S., additional, Reid, A., additional, Benyon, S., additional, Murphy, C., additional, Soliman, F., additional, Lefemine, V., additional, Saha, S., additional, Ogedegbe, K., additional, Olyinka, O.S., additional, Dicks, J.R., additional, Manoloudakis, N., additional, Conroy, F., additional, Irwin, G., additional, McIntosh, S., additional, Michalakis, I., additional, Hignett, S., additional, Linforth, R., additional, Rathinaezhil, R., additional, Osman, H., additional, Anesti, K., additional, Griffiths, M., additional, Jacklin, R., additional, Waterworth, A., additional, Foulkes, R., additional, Davies, E., additional, Bisarya, K., additional, Allan, A., additional, Leon-Villapalos, J., additional, Mazari, F.A.K., additional, Azmy, I., additional, George, S., additional, Fahmy, F.S., additional, Hargreaves, A., additional, Seward, J., additional, Henton, J., additional, Collin, T., additional, Mallon, P., additional, Turner, J., additional, Sarakbi, W., additional, Athanasiou, I., additional, Rogers, C., additional, Youssef, M., additional, Graja, T., additional, Huf, S., additional, Deol, H., additional, Brindle, R., additional, Gawne, S., additional, Egbeare, D., additional, Dash, I., additional, Galea, M., additional, Laws, S., additional, Tayeh, S., additional, Parvanta, L., additional, Down, S., additional, Westbroek, D., additional, Roberts, J.W., additional, Massey, J., additional, Turton, P., additional, Achuthan, R., additional, Fawzy, M., additional, Dickson, M., additional, Carmichael, A.R., additional, Akingboye, A., additional, James, R., additional, Kirkpatrick, K., additional, Nael, E., additional, Vidya, R., additional, Thorne, A., additional, Rostom, M., additional, Depasquale, I., additional, Cawthorn, S.J., additional, Gangamihardja, T., additional, Joglekar, S., additional, Smith, J., additional, Halka, A., additional, MacMillan, D., additional, Clark, S., additional, Pearce, B., additional, Mansfield, L., additional, King, I., additional, Hazari, A., additional, Smith, B., additional, Volleamere, A.J., additional, Ferguson, D., additional, Barnes, N., additional, Knight, A., additional, MacNeill, F., additional, Conway, A., additional, Irvine, T., additional, Mylavaganam, S., additional, Dunne, N., additional, Kohlhardt, S., additional, Hoo, C., additional, Kirk, S., additional, Hu, J., additional, Ledwidge, S., additional, Tang, S., additional, Banerjee, D., additional, Waheed, S., additional, Voynov, V., additional, Soumian, S., additional, Henderson, J., additional, Harvey, J., additional, Robertson, S., additional, Waters, R., additional, Carbone, A., additional, Skillman, J., additional, Farooq, Ansar, additional, Tafazal, H., additional, Clarke, D., additional, Cocker, D., additional, Lai, L.M., additional, Winter Beatty, J., additional, Barkeji, M., additional, Vinayagam, R., additional, Mullan, M., additional, Osborne, C., additional, Baker, E., additional, and Piper, J., additional

Published
2018
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45. Steady-state and transient photoconductivity in c-axis GaN nanowires grown by nitrogen-plasma-assisted molecular beam epitaxy.

Author

Sanford, N. A., Blanchard, P. T., Bertness, K. A., Mansfield, L., Schlager, J. B., Sanders, A. W., Roshko, A., Burton, B. B., and George, S. M.

Subjects
PHOTOCONDUCTIVITY, GALLIUM nitride, NANOWIRES, MOLECULAR beam epitaxy, NITROGEN plasmas, HOLES (Electron deficiencies)
Abstract

Analysis of steady-state and transient photoconductivity measurements at room temperature performed on c-axis oriented GaN nanowires yielded estimates of free carrier concentration, drift mobility, surface band bending, and surface capture coefficient for electrons. Samples grown (unintentionally n-type) by nitrogen-plasma-assisted molecular beam epitaxy primarily from two separate growth runs were examined. The results revealed carrier concentration in the range of (3–6)×1016 cm-3 for one growth run, roughly 5×1014–1×1015 cm-3 for the second, and drift mobility in the range of 500–700 cm2/(V s) for both. Nanowires were dispersed onto insulating substrates and contacted forming single-wire, two-terminal structures with typical electrode gaps of ≈3–5 μm. When biased at 1 V bias and illuminated at 360 nm (3.6 mW/cm2) the thinner (≈100 nm diameter) nanowires with the higher background doping showed an abrupt increase in photocurrent from 5 pA (noise level) to 0.1–1 μA. Under the same conditions, thicker (151–320 nm) nanowires showed roughly ten times more photocurrent, with dark currents ranging from 2 nA to 1 μA. With the light blocked, the dark current was restored in a few minutes for the thinner samples and an hour or more for the thicker ones. The samples with lower carrier concentration showed similar trends. Excitation in the 360–550 nm range produced substantially weaker photocurrent with comparable decay rates. Nanowire photoconductivity arises from a reduction in the depletion layer via photogenerated holes drifting to the surface and compensating ionized surface acceptors. Simulations yielded (dark) surface band bending in the vicinity of 0.2–0.3 V and capture coefficient in the range of 10-23–10-19 cm2. Atomic layer deposition (ALD) was used to conformally deposit ≈10 nm of Al2O3 on several devices. Photoconductivity, persistent photoconductivity, and subgap photoconductivity of the coated nanowires were increased in all cases. TaN ALD coatings showed a reduced effect compared to the Al2O3 coated samples. [ABSTRACT FROM AUTHOR]

Published
2010
Full Text
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46. British Thoracic Society Guideline for oxygen use in adults in healthcare and emergency settings

Author

O'Driscoll, B R, Howard, L S, Eavis, J, Mak, V, Bajwah, S, Beasley, R, Curtis, K, Davison, A, Dorward, A, Dyer, C, Evans, A, Falconer, L, Fitzpatrick, C, Gibbs, S, Hinshaw, K, Howard, R, Kane, B, Keep, J, Kelly, Carol, Khachi, H, Khan, MAI, Kishen, R, Mansfield, L, Martin, B, Moore, F, Powrie, D, Restrick, L, Roffe, C, Singer, M, Soar, J, Small, I, Ward, L, Whitmore, D, Wedzicha, W, Wijesinghe, M, O'Driscoll, B R, Howard, L S, Eavis, J, Mak, V, Bajwah, S, Beasley, R, Curtis, K, Davison, A, Dorward, A, Dyer, C, Evans, A, Falconer, L, Fitzpatrick, C, Gibbs, S, Hinshaw, K, Howard, R, Kane, B, Keep, J, Kelly, Carol, Khachi, H, Khan, MAI, Kishen, R, Mansfield, L, Martin, B, Moore, F, Powrie, D, Restrick, L, Roffe, C, Singer, M, Soar, J, Small, I, Ward, L, Whitmore, D, Wedzicha, W, and Wijesinghe, M

Abstract

The full Guideline for oxygen use in adults in healthcare and emergency settings, published in Thorax1 provides an update to the 2008 BTS Emergency oxygen guideline.2 The following is a summary of the recommendations and good practice points. The sections noted to within this summary refer to the full guideline sections.

Published
2017

47. Linking Physical Activity & Health Evaluation to Policy: Lessons from UK Evaluations

Author

Piggin, J, Weed, M, Mansfield, L, Pringle, AR, McKenna, J, Zwolinsky, S, Piggin, J, Weed, M, Mansfield, L, Pringle, AR, McKenna, J, and Zwolinsky, S

Abstract

Evaluation is an important component of contemporary physical activity (PA) interventions. In this chapter, we provide a series of peer-review case studies that we have been involved. We comment on a number of issues and debates on the role of evaluation in PA policy and interventions. The case studies selected originated in local and or national policy. To identify these cases, we applied two key criteria set elsewhere (Pringle, Hargreaves Lozano et al., 2014): (I) Credibility: Cases represent real world illustrations of the place of evaluation in a policy context. (II). Impact: Cases identify their effects. The case studies provide applied, insightful, contextual and practical examples of partnership evaluations in both PA intervention and policy. Emerging from these case studies are a number of lessons for how evaluation is performed. We share this learning so it may shape future evaluation practice in physical activity and public health.

Published
2017

48. ESICM LIVES 2016: part two

Author

Sivakumar, S., Taccone, F. S., Desai, K. A., Lazaridis, C., Skarzynski, M., Sekhon, M., Henderson, W., Griesdale, D., Chapple, L., Deane, A., Williams, L., Strickland, R., Lange, K., Heyland, D., Chapman, M., Rowland, M. J., Garry, P., Westbrook, J., Corkill, R., Antoniades, C. A., Pattinson, K. T., Fatania, G., Strong, A. J., Myers, R. B., Jermaine, C. M., Robertson, C. S., Rusin, C. G., Hofmeijer, J., Sondag, L., Tjepkema-Cloostermans, M. C., Beishuizen, A., Bosch, F. H., van Putten, M. J. A. M., Carteron, L., Patet, C., Solari, D., Oddo, M., Ali, M. A., Dias, C., Almeida, R., Vaz-Ferreira, A., Silva, J., Monteiro, E., Cerejo, A., Rocha, A. P., Elsayed, A. A., Abougabal, A. M., Beshey, B. N., Alzahaby, K. M., Pozzebon, S., Ortiz, A. Blandino, Cristallini, S., Lheureux, O., Brasseur, A., Vincent, J. L., Creteur, J., Hravnak, M., Yousef, K., Chang, Y., Crago, E., Friedlander, R. M., Abdelmonem, S. A., Tahon, S. A., Helmy, T. A., Meligy, H. S., Puig, F., Dunn-Siegrist, I., Pugin, J., Gupta, S., Govil, D., Srinivasan, S., Patel, S. J., N, J. K., Gupta, A., Tomar, D. S., Shafi, M., Harne, R., Arora, D. P., Talwar, N., Mazumdar, S., Papakrivou, E. E., Makris, D., Manoulakas, E., Tsolaki, B., Karadodas, B., Zakynthinos, E., Garcia, I. Palacios, Martin, A. Diaz, Encinares, V. Sanchez, Ibañez, M. Pachón, Montero, J. Garnacho, Labrador, G., Cangueiro, T. Cebrero, Poulose, V., Koh, J., Kam, J. W., Yeter, H., Kara, A., Aktepe, O., Topeli, A., Tsolakoglou, I., Intas, G., Stergiannis, P., Kolaros, A. A., Chalari, E., Athanasiadou, E., Martika, A., Fildisis, G., Faivre, V., Mengelle, C., Favier, B., Payen, D., Poppe, A., Winkler, M. S., Mudersbach, E., Schreiber, J., Wruck, M. L., Schwedhelm, E., Kluge, S., Zöllner, C., Tavladaki, T., Spanaki, A. M., Dimitriou, H., Kondili, E., Choulaki, C., Meleti, E., Kafetzopoulos, D., Georgopoulos, D., Briassoulis, G., la Torre, A. García-de, de la Torre-Prados, M. V., Tsvetanova-Spasova, T., Nuevo-Ortega, P., Rueda-Molina, C., Fernández-Porcel, A., Camara-Sola, E., Salido-Díaz, L., García-Alcántara, A., Meleti, D. E., Suberviola, B., Riera, J., Rellan, L., Sanchez, M., Robles, J. C., Lopez, E., Vicente, R., Miñambres, E., Santibañez, M., Le Guen, M., Moore, J., Mason, N., Windpassinger, M., Plattner, O., Mascha, E., Sessler, D. I., Research, Outcomes, Melia, U., Fontanet, J., van den Berg, J. P., Struys, M. M. R. F., Vereecke, H. E. M., Jensen, E. W., Rood, P. J. T., van de Schoor, F., van Tertholen, K., Pickkers, P., van den Boogaard, M., Beardow, Z. J., Redhead, H., Paramasivam, K., Numan, T., Kamper, A. M., Rood, P., Peelen, L. M., Zeman, P. M., Slooter, A. J., van Ewijk, C. E., Jacobs, G. E., Girbes, A. R. J., Myatra, S. N., Harish, M. M., Prabu, N. R., Siddiqui, S., Kulkarni, A. P., Divatia, J. V., Murbach, L. D., Leite, M. A., Osaku, E. F., Costa, C. R. L. M., Pelenz, M., Neitzke, N. M., Moraes, M. M., Jaskowiak, J. L., Silva, M. M. M., Zaponi, R. S., Abentroth, L. R. L., Ogasawara, S. M., Jorge, A. C., Duarte, P. A. D., Hernández-Sánchez, N., Sánchez-Hurtado, L. A., García-Guillen, F. J., Ñamendys-Silva, S. A., Maghsoudi, B., Emami, M., Khosravi, M. B., Zand, F., Tabatabaie, H. R., Masjedi, M., Sabetiyan, G., Mokri, A., Troubleyn, J., Diltoer, M., Jacobs, R., Nguyen, D. N., De Waele, E., De Regt, J., Honoré, P. M., Van Gorp, V., Spapen, H. D., Contreras, R. S., Toapanta, N. D., Moreno, G., Sabater, J., Torrado, H., Gonzalez, M., Marin, M., Farigola, E., Gonzalez, A., Fernandez, J., Vera, A., Gisbert, X., Juliá, C., Uya, J., Corral, L., Elias-Jones, I., Gemmell, L., MacKay, A., Randall, D., Adwaney, A., Blunden, M., Prowle, J. R., Kirwan, C. J., Thomas, N., Martin, A., Owen, H., Darwin, L., Conway, D., Atkinson, D., Sharman, M., Barbanti, C., Amour, J., Gaudard, P., Rozec, B., Mauriat, P., M’rini, M., Leger, P. L., Cambonie, G., Liet, J. M., Girard, C., Laroche, S., Damas, P., Assaf, Z., Loron, G., Lecourt, L., Pouard, P., Prowle, J.R., Kim, S. H., Na, S., Kim, J., Oh, S. Y., Jung, C. W., Yoo, S. H., Min, S. H., Chung, E. J., Lee, H., Lee, N. J., Lee, K. W., Suh, K. S., Ryu, H. G., Marshall, D. C., Goodson, R. J., Salciccioli, J. D., Shalhoub, J., Potter, E. K., Kirk-Bayley, J., Karanjia, N. D., Forni, L. G., Creagh-Brown, B. C., Bossy, M., Nyman, M., Tailor, A., Creagh-Brown, B., D’Antini, D., Spadaro, S., Valentino, F., Sollitto, F., Cinnella, G., Mirabella, L., Calvo, F. J. Redondo, Bejarano, N., Padilla, D., Baladron, V., Villajero, P., Villazala, R., Redondo, J., Yuste, A. S., Liu, J., Shen, F., Teboul, J. L., Anguel, N., Beurton, A., Bezaz, N., Richard, C., Monnet, X., Fossali, T., Colombo, R., Ottolina, D., Rossetti, M., Mazzucco, C., Marchi, A., Porta, A., Catena, E., Tollisen, K. H., Andersen, G. Ø., Heyerdahl, F., Jacobsen, D., de Waard, M. C., van IJzendoorn, M. C. O., Buter, H., Kingma, W. P., Navis, G. J., Boerma, E. C., Rulisek, J., Balik, M., Zacharov, S., Kim, H. S., Jeon, S. J., Namgung, H., Lee, E., Cho, Y. J., Lee, Y. J., Huang, A., Cioccari, L., Luethi, N., Mårtensson, J., Bellomo, R., Forsberg, M., Edman, G., Höjer, J., Forsberg, S., Freile, M. T. Chiquito, Hidalgo, F. N., Molina, J. A. Martinez, Lecumberri, R., Rosselló, A. Figuerola, Travieso, P. Medrano, Leon, G. Tuero, Sanchez, J. Gonzalez, Frias, L. Sahuquillo, Rosello, D. Balsells, Verdejo, J. A. Garcia, Serrano, J. A. Noria, Winterwerp, D., van Galen, T., Vazin, A., Karimzade, I., Zand, A., Ozen, E., Ekemen, S., Akcan, A., Sen, E., Yelken, B. Buyukkidan, Kureshi, N., Fenerty, L., Thibault-Halman, G., Erdogan, M., Walling, S., Green, R. S., Clarke, D. B., Briassoulis, P., Kalimeris, K., Ntzouvani, A., Nomikos, T., Papaparaskeva, K., Politi, E., Kostopanagiotou, G., Crewdson, K., Rehn, M., Weaver, A., Brohi, K., Lockey, D., Wright, S., Thomas, K., Baker, C., Mansfield, L., Stafford, V., Wade, C., Watson, G., Bryant, A., Chadwick, T., Shen, J., Wilkinson, J., Furneval, J., Henderson, A., Hugill, K., Howard, P., Roy, A., Bonner, S., Baudouin, S., Ramírez, C. Sánchez, Escalada, S. Hípola, Viera, M. A. Hernández, Santana, M. Cabrera, Balcázar, L. Caipe, Monroy, N. Sangil, Campelo, F. Artiles, Vázquez, C. F. Lübbe, Santana, P. Saavedra, Santana, S. Ruiz, Quintard, H., Bouzat, P., Wollersheim, T., Malleike, J., Haas, K., Carbon, N., Schneider, J., Birchmeier, C., Fielitz, J., Spuler, S., Weber-Carstens, S., Enseñat, L., Pérez-Madrigal, A., Saludes, P., Proença, L., Gruartmoner, G., Espinal, C., Mesquida, J., Huber, W., Eckmann, M., Elkmann, F., Gruber, A., Lahmer, T., Mayr, U., Herner, A., Schellnegger, R., Schmid, R. M., Ayoub, W., Samy, W., Esmat, A., Battah, A., Mukhtar, S., Mongkolpun, W., Cortés, D. Orbegozo, Cordeiro, C. P. R., Funcke, S., Groesdonk, H., Saugel, B., Wagenpfeil, G., Wagenpfeil, S., Reuter, D. A., Fernandez, M. M., Fernandez, R., Magret, M., González-Castro, A., Bouza, M. T., Ibañez, M., García, C., Balerdi, B., Mas, A., Arauzo, V., Añón, J. M., Ruiz, F., Ferreres, J., Tomás, R., Alabert, M., Tizón, A. I., Altaba, S., Llamas, N., Goligher, E C., Fan, E., Herridge, M., Vorona, S., Sklar, M., Dres, M., Rittayamai, N., Lanys, A., Urrea, C., Tomlinson, G., Reid, W. D., Rubenfeld, G. D., Kavanagh, B. P., Brochard, L. J., Ferguson, N. D., Neto, A. Serpa, de Abreu, M. Gama, Pelosi, P., Schultz, M. J., Guérin, C., Papazian, L., Reignier, J., Ayzac, L., Loundou, A., Forel, J. M., Rolland-Debord, C., Bureau, C., Poitou, T., Clavel, M., Perbet, S., Terzi, N., Kouatchet, A., Similowski, T., Demoule, A., Hunfeld, N., Trogrlic, Z., Ladage, S., Osse, R. J., Koch, B., Rietdijk, W., Devlin, J., van der Jagt, M., Picetti, E., Ceccarelli, P., Mensi, F., Malchiodi, L., Risolo, S., Rossi, I., Antonini, M. V., Servadei, F., Caspani, M. L., Roquilly, A., Lasocki, S., Seguin, P., Geeraerts, T., Perrigault, P. F., Dahyot-Fizelier, C., Paugam-Burtz, C., Cook, F., Cinotti, R., dit Latte, D. Demeure, Mahe, P. J., Fortuit, C., Feuillet, F., Asehnoune, K., Marzorati, C., Spina, S., Scaravilli, V., Vargiolu, A., Riva, M., Giussani, C., Sganzerla, E., Citerio, G., Barbadillo, S., de Molina, F. J. González, Álvarez-Lerma, F., Rodríguez, A., Zakharkina, T., Martin-Loeches, I., Matamoros, S., Povoa, P., Torres, A., Kastelijn, J., Hofstra, J. J., de Jong, M., Schultz, M., Sterk, P., Artigas, A., Bos, L. J., Moreau, A. S., Salluh, J., Rodriguez, A., Nseir, S., de Jong, E., van Oers, J. A., Nijsten, M. W. N., de Lange, D. W., Bonvicini, D., Labate, D., Benacchio, L., Olivieri, A., Pizzirani, E., Lopez-Delgado, J. C., Gonzalez-Romero, M., Fuentes-Mila, V., Berbel-Franco, D., Romera-Peregrina, I., Martinez-Pascual, A., Perez-Sanchez, J., Abellan-Lencina, R., Ávila-Espinoza, R. E., Moreno-Gonzalez, G., Sbraga, F., Griffiths, S., Grocott, M. P. W., Doyle, J., Wilkerson, P., Soon, Y., Huddart, S., Dickinson, M., Riga, A., Zuleika, A., Miyamoto, K., Kawazoe, Y., Morimoto, T., Yamamoto, T., Fuke, A., Hashimoto, A., Koami, H., Beppu, S., Katayama, Y., Ito, M., Ohta, Y., Yamamura, H., Rygård, S. L., Holst, L B., Wetterslev, J., Johansson, P. I., Perner, A., Soliman, I. W., van Dijk, D., van Delden, J. J. M., Cremer, O. L., Slooter, A. J. C., McWilliams, D., Snelson, C., Neves, A. Das, Loudet, C. I., Busico, M., Vazquez, D., Villalba, D., Veronesi, M., Lischinsky, A., López, F. J. L., Mori, L. Benito, Plotnikow, G., Díaz, A., Giannasi, S., Hernandez, R., Krzisnik, L., Cecotti, C., Viola, L., Lopez, R., Sottile, J. P., Benavent, G., Estenssoro, E., Chen, C. M., Lai, C. C., Cheng, K. C., Chou, W., Chan, K. S., Roeker, L. E., Horkan, C. M., Gibbons, F. K., Christopher, K. B., Weijs, P. J. M., Mogensen, K. M., Rawn, J. D., Robinson, M. K., Tang, Z., Qiu, C., Ouyang, B., Cai, C., Guan, X., Regueira, T., Cea, L., Carlos, S. Juan, Elisa, B., Puebla, C., Vargas, A., Poulsen, M. K., Thomsen, L. P., Kjærgaard, S., Rees, S. E., Karbing, D. S., Frank, S., Müller, M. C., Carbon, N. M., Skrypnikov, V., Pickerodt, P. A., Falk, R., Mahlau, A., Lee, A., Inglis, R., Morgan, R., Barker, G., Kamata, K., Abe, T., Saitoh, D., Tokuda, Y., Butler, M. B., Hwa, H. Tae, Gil, L. Jae, Vaquero, R. Hernández, Rodriguez-Ruiz, E., Lago, A. Lopez, Allut, J. L. Garcia, Gestal, A. Estany, Gonzalez, M. A. Garcia, Thomas-Rüddel, D. O., Schwarzkopf, D., Fleischmann, C., Reinhart, K., Suwanpasu, S., Sattayasomboon, Y., Filho, N. M. Filgueiras, Oliveira, J. C. A., Ballalai, C. S., De Lucia, C. V., Araponga, G. P., Veiga, L. N., Silva, C. S., Garrido, M. E., Ramos, B. B., Ricaldi, E. F., Gomes, S. S., Wright, C., Docking, R. I., Doherty, P., Black, E., Stenhouse, P., Plummer, M. P., Finnis, M. E., Phillips, L. K., Kar, P., Bihari, S., Biradar, V., Moodie, S., Horowitz, M., Shaw, J. E., Deane, A. M., Yatabe, T., Inoue, S., Sakaguchi, M., Egi, M., Abdelhamid, Y. Ali, Hokka, M., Mizobuchi, S., Plummer, M., Giersch, E., Summers, M., Hatzinikolas, S., Heller, S., Jones, K., Schweizer, R., Jacquet-Lagreze, M., Portran, P., Junot, S., Allaouchiche, B., Fellahi, J. L., Guerci, P., Ergin, B., Kapucu, A., Ince, C., Crisman, M., Shinotsuka, C. Righy, Fagnoul, D., Orbegozo, D., Preiser, J. C., Thooft, A., Brimioulle, S., Iwasaka, H., Tahara, S., Nagamine, M., Ichigatani, A., Cabrera, A. Rugerio, Zepeda, E. Monares, Granillo, J. Franco, Sánchez, J. S. Aguirre, Montoya, A. A. Tanaka, Montenegro, A. Pedraza, Blanco, G. A. Gálvez, Robles, C. M. Coronado, Drolz, A., Horvatits, T., Roedl, K., Rutter, K., Funk, G. C., Schneeweiss, B., Fuhrmann, V., Sabetian, G., Pooresmaeel, F., Ghaffaripour, S., Farbod, A., Tabei, H., Taheri, L., Anandanadesan, R., Metaxa, V., Teixeira, C., Pereira, S. M., Hernández-Marrero, P., Carvalho, A. S., Beckmann, M., Hartog, C. S., Raadts, A., Robertsen, A., Førde, R., Skaga, N. O., Helseth, E., Honeybul, S., Ho, K., Lopez, P. Martinez, Gonzalez, M. Nieto, Ortega, P. Nuevo, Sola, E. Camara, Spasova, T., Kopecky, O., Rusinova, K., Waldauf, P., Cepeplikova, Z., Domínguez, J. Palamidessi, Almudevar, P. Matia, Carmona, S. Alcántara, Muñoz, J. J. Rubio, Castañeda, D. Palacios, Abellán, A. Naharro, Villamizar, P. Rodríguez, Ramos, J. Veganzones, Pérez, L. Pérez, Lucendo, A. Pérez, Ejarque, M. Camós, Estella, A., Camps, V. Lopez, Martín, M. C., Masnou, N., Barbosa, S., Varela, A., Palma, I., Cristina, L., Nunes, E., Pereira, I., Campello, G., Granja, C., Pande, R., Pandey, M., Varghese, S., Chanu, M., Van Dam, M. J., Ter Braak, E. W. M. T., Gracia, M., Viciana, R., Recuerda, M., Fontaiña, L. Perez, Tharmalingam, B., Kovari, F., Rose, L., Mcginlay, M., Amin, R., Burns, K., Connolly, B., Hart, N., Jouvet, P., Katz, S., Leasa, D., Mawdsley, C., Mcauley, D., Blackwood, B., Denham, S., Worrall, R., Arshad, M., Isherwood, P., Khadjibaev, A., Sabirov, D., Rosstalnaya, A., Parpibaev, F., Sharipova, V., Blanco, G. A. Galvez, Guzman, C. I. Olvera, Cha, Y. S., Lee, S. J., Tyagi, N., Rajput, R. K., Taneja, S., Singh, V. K., Sharma, S. C., Mittal, S., Rao, B. K., Ayachi, J., Fraj, N., Romdhani, S., Khedher, A., Meddeb, K., Sma, N., Azouzi, A., Bouneb, R., Chouchene, I., El Ghardallou, M., Boussarsar, M., Jennings, R., Walter, E., Ribeiro, J. M., Moniz, I., Marçal, R., Santos, A. C., Candeias, C., e Silva, Z. Costa, Gomez, S. E. Zamora, Nieto, O. R. Perez, Gonzalez, J. A. Castanon, Cuellar, A. I. Vasquez, Mildh, H., Pettilä, V., Korhonen, A. M., Karlsson, S., Ala-Kokko, T., Reinikainen, M., Vaara, S. T., Zaleska-Kociecka, M., Grabowski, M., Dąbrowski, M., Wozniak, S., Piotrowska, K., Banaszewski, M., Imiela, J., Stepinska, J., Pérez, A. González, Ordoñez, P. Florez, Giribet, A., Cuervo, M. A. Alonso, Cuervo, R. Alonso, Esteban, M. A. Rodriguez, Fraile, L. Iglesias, Mittelbrum, C. Ponte, Albaiceta, G. Muñiz, Koeze, J., Keus, F., Dieperink, W., van der Horst, I. C. C., van Meurs, M., Zijlstra, J. G., Roberts, S., Caballero, C. Hernandez, Isgro, G., Hall, D., Beitland, S., Trøseid, A.-M. S., Brusletto, B. S., Waldum-Grevbo, B. E., Berg, J. P., Sunde, K., Huertas, D. García, Manzano, F., Quintana, M. M. Jiménez, Osuna, A., Santiago-Ruiz, F., Rodríguez-Mejías, C., Wangensteen, R., Jamaati, H. R., Hashemian, S. M. R., Abbasi, G., Khaloo, V., Tabei, S. H.a., Kafilzadeh, A., Bakhodaei, H. Haddad, Diaz, J. A., Silva, R., Garcia, D. J., Luis, E., Gomez, M. N., Soriano, R., Gonzalez, P. L., Ibrahim, I. A., Rafik, M. M., Al-Ansary, A. M., Algendi, M. A., Ali, A. A., Benten, D., Kluwe, J., Siedler, S., Adedugbe, I., Bird, G. T., Kennedy, R. M., Sharma, S., Yugi, G., Haroon, B. A., Witter, T., Khaliq, W., Singer, M., Havaldar, A. A., Krishna, B., Sriram, S., Espinoza, E. D. Valenzuela, Pozo, M. O., Edul, V. S. Kanoore, Furche, M., Motta, M. F., Vazquez, A. Risso, Birri, P. N. Rubatto, Dubin, A., Dogliotti, A., Ramos, A., Lovesio, C., Delile, E., Nevière, R., Thiébaut, P.-A., Maupoint, J., Mulder, P., Coquerel, D., Renet, S., do Rego, J. C., Rieusset, J., Richard, V., Tamion, F., Andreis, D. T., Smit, B., Smulders, Y. M., van Straaten, H. M. Oudemans, Eringa, E. C., Man, A. M. E. Spoelstra-de, Alegría, L., Soto, D., Luengo, C., Gomez, J., Jarufe, N., Bruhn, A., Castro, R., Kattan, E., Tapia, P., Rebolledo, R., Achurra, P., Ospina-Tascón, G., Bakker, J., Hernández, G., Bertini, P., Guarracino, F., Baldassarri, R., Pinsky, M. R., Vera, M., Dreyse, J., Carpio, D., Henriquez, C., Gajardo, D., Bravo, S., Kim, S., Lee, M., Park, S. Y., So, S., Kačar, M. B., Kačar, S. M., Uddin, I., Belhaj, A. M., Aydın, M. A., Avsec, D., Kapuağası, A., Kaymak, Ç., Kovach, L., Şencan, İ., Meço, B., Özçelik, M., Ünal, N., Jenni-Moser, B., Jeitziner, M.-M., Galassi, M. S., Sales, F. L., de Moraes, K. C. L., Batista, C. L., Júnior, J. A. de Souza, Marcari, T. B., Lobato, R., Castro, C. S. A. A., de Souza, L. M., Rodrigues, F. F. P., Correa, N. G., Pelegrini, A. M., Eid, R. A. C., Timenetsky, K. T., Cazati, D., Lobato, M., Diniz, P. S., Rocha, L. L., Cavalheiro, A. M., Lucinio, N. M., Santos, E. R., Norrenberg, M., Gleize, A., Simón, I. Fernández, Valhonrat, I. Lipperheide, Almudévar, P. Matía, Dávila, F., Rubio, J. J., Ramos, A. J., Reina, Á. J. Roldán, López, N. Palomo, Pérez, M. Adriaensens, Apolo, D. X. Cuenca, Villén, L. Martín, López, F. M. Porras, García, I. Palacios, Izurieta, J. R. Naranjo, Guerrero, J. J. Egea, Calvert, S., Quint, M., Adeniji, K., Young, R., Shevill, D. D., Robertson, E., Garside, P., Isotti, P., De Vecchi, M. M., Perduca, A. E., Negro, A., Villa, G., Manara, D. F., Cabrini, L., Zangrillo, A., Frencken, J. F., van Baal, L., Donker, D. W., Horn, J., van der Poll, T., van Klei, W. A., Bonten, M. J. M., Menard, C. E., Kumar, A., Rimmer, E., Doucette, S., Turgeon, A. F., Houston, B. L., Houston, D. S., Zarychanski, R., Pinto, B. Bollen, Carrara, M., Ferrario, M., Bendjelid, K., Nunes, J., Diaz, P., Silva, G., Escórcio, S., Chaves, S., Jardim, M., Fernandes, N., Câmara, M., Duarte, R., Pereira, C. A., Vieira, J., Nóbrega, J. J., de Oca-Sandoval, M. A. Montes, Sánchez-Rodríguez, A., Joya-Galeana, J. G., Correa-Morales, A., Camarena-Alejo, G., Aguirre-Sánchez, J., Franco-Granillo, J., Soliman, M., Al Azab, A., El Hossainy, R., Nagy, H., Nirmalan, M., Crippa, I. A., Cavicchi, F. Zama, Chaari, A., Hakim, K. Abdel, Hassanein, H., Etman, M., El Bahr, M., Bousselmi, K., Khalil, E. S., Kauts, V., Casey, W. F., Imahase, H., Sakamoto, Y., Yamada, K. C., Miike, T., Nagashima, F., Iwamura, T., Boscolo, A., Lucchetta, V., Piasentini, E., Bertini, D., Manesso, L., Spiezia, L., Simioni, P., Ori, C., Souza, R. B., Martins, A. M., Liberatore, A. M. A., Kang, Y. R., Nakamae, M. N., Vieira, J. C. F., Koh, I. H. J., Hanslin, K., Wilske, F., Skorup, P., Sjölin, J., Lipcsey, M., Long, W. Jin, Zhen, C. Er, Vakalos, A., Avramidis, V., Wu, S. H., Shyu, L. J., Li, C. H., Yu, C. H., Chen, H. C., Wang, C. H., Lin, K. H., Aray, Z. E., Gómez, C. F., Tejero, A. P., Monge, D. D., Losada, V. M., Tarancón, C. M., Cortés, S. D., Gutiérrez, A. M., Álvarez, T. P., Rouze, A., Jaffal, K., Six, S., Stolz, K., Cattoen, V., Arnal, J. M., Saoli, M., Novotni, D., Garnero, A., Becher, T., Buchholz, V., Schädler, D., Frerichs, I., Weiler, N., Eronia, N., Mauri, T., Gatti, S., Maffezzini, E., Bronco, A., Alban, L., Sasso, T., Marenghi, C., Grasselli, G., Pesenti, A., Bellani, G., Al-Fares, A., Del Sorbo, L., Anwar, S., Facchin, F., Azad, S., Zamel, R., Ferguson, N., Cypel, M., Keshavjee, S., Durlinger, E., Spoelstra-de Man, A., de Grooth, H. J., Girbes, A., Straaten, H. Oudemans-van, Smulders, Y., Alfaro, M. A., Parrilla, F., Meli, A., Pellegrini, M., Rodriguez, N., Goyeneche, J. M., Morán, I., Aguirre, H., Mancebo, J., Heines, S. J. H., Strauch, U., Bergmans, D. C. J. J., Blankman, P., Shono, A., Hasan, D., Gommers, D., Chung, W. Y., Lee, K. S., Jung, Y. J., Park, J. H., Sheen, S. S., Park, K. J., Worral, R., Larraza, S., Dey, N., Brohus, J. B., Winding, R. W., Volta, C. A., Ampatzidou, F., Vlachou, A., Kehagioglou, G., Karaiskos, T., Madesis, A., Mauromanolis, C., Michail, N., Drossos, G., Saraj, N., Rijkenberg, S., Feijen, H. M., Endeman, H., Donnelly, A. A. J., Morgan, E., Garrard, H., Buckley, H., Russell, L., Haase, N., Goh, C., Mouyis, K., Woodward, C. L. N., Halliday, J., Encina, G. B., Ros, J., Lagunes, L., Tabernero, J., Bosch, F., Rello, J., Morente-Constantin, E., Rivera-Ginés, B., Colmenero-Ruiz, M., Sanz, J. García, Simon, I. Fernandez, Valbuena, B. Lobo, Carmona, S. Alcantara, Pais, M., Ramalingam, S., Díaz, C., Fox, L., Santafe, M., Barba, P., García, M., Leal, S., Pérez, M., Pérez, M. L. Pérez, Veganzones, J., Simón, I. Fernandez, Martínez, N., Moors, I., Mokart, D., Pène, F., Lambert, J., Mayaux, J., Vincent, F., Nyunga, M., Bruneel, F., Laisne, L., Rabbat, A., Lebert, C., Perez, P., Chaize, M., Renault, A., Meert, A. P., Hamidfar, R., Jourdain, M., Darmon, M., Schlemmer, B., Chevret, S., Lemiale, V., Azoulay, E., Benoit, D., Martins-Branco, D., Sousa, M., Marum, S., Bouw, M. J., Galstyan, G., Makarova, P., Parovichnikova, E., Kuzmina, L., Troitskaya, V., Drize, N., Gemdzhian, E., Savchenko, V., Chao, H. C., Kılıc, E., Demiriz, B., Uygur, M. L., Sürücü, M., Cınar, K., Yıldırım, A. E., Kiss, K., Köves, B., Csernus, V., Molnár, Z., Ntantana, A., Matamis, D., Savvidou, S., Giannakou, M., Gouva, M., Nakos, G., Koulouras, V., Gaffney, S., Docking, R., Judge, C., Drew, T., Misran, H., Munshi, R., McGovern, L., Coyle, M., Dunne, L., Deasy, E., Lavin, P., Fahy, A., Darcy, D. M., Donnelly, M., Ismail, N. H., Hall, T., Wykes, K., Jack, J., Ngu, W. C., Morgan, P., Ruiz-Ramos, J., Ramirez, P., Gordon, M., Villarreal, E., Frasquet, J., Poveda-Andrés, J. L., Castellanos, A., Ijssennagger, C. E., ten Hoorn, S., van Wijk, A., van den Broek, J. M., Tuinman, P. R., Elmenshawy, A. M., Hammond, B. 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T., Russ, M., Braun, W., Walter, M., Francis, R., Lachmann, B., Leonhardt, S., Landaverde-López, A., Canedo-Castillo, N. A., Esquivel-Chávez, A., Arvizu-Tachiquín, P. C., Baltazar-Torres, J. A., Cardoso, V., Krystopchuk, A., Castro, S., Melão, L., Firmino, S., Marreiros, A., Almaziad, S., Kubbara, A., Barnett, W., Nakity, R., Alamoudi, W., Altook, R., Tarazi, T., Fida, M., Safi, F., Assaly, R., Santini, A., Milesi, M., Maraffi, T., Pugni, P., Cavenago, M., Gattinoni, L., Protti, A., Perchiazzi, G., Borges, J. B., Bayat, S., Porra, L., Broche, L., Hedenstierna, G., Larsson, A., Roneus, A., Segelsjö, M., Vestito, M. C., Gremo, E., Nyberg, A., Castegren, M., Pikwer, A., Yoshida, T., Engelberts, D., Otulakowski, G., Katira, B., Post, M., Brochard, L., Amato, M. B. P., Koch, N., Hoellthaler, J., Mair, S., Phillip, V., Beitz, A., Baladrón, V., Villarejo, P., Steenstra, R. J., Banierink, H., Hof, J., van der Horst, I. C., Nijsten, M. W., Hoekstra, M., Sterz, F., Horvatits, K., Herkner, H., Kott, M., Zitta, K., Brandt, B., Schildhauer, C., Elke, G., Hummitzsch, L., Albrecht, M., González, L. Rey, Alonso, D. Cabestrero, Sánchez, R. de Pablo, Lucas, J. Higuera, Ferlitsch, A., Fauler, G., Trauner, M., Pischke, S., Fischer, L., Thaiss, F., Koch, M., Bangert, K., Lohse, A. W., Nashan, B., Sterneck, M., Faenza, S., Siniscalchi, A., Pierucci, E., Mancini, E., Ricci, D., Gemelli, C., Cuoghi, A., Magnani, S., Atti, M., Sotos, F., Cánovas, J., López, A., Burruezo, A., Torres, D., Herrera-Gutierrez, M. E., Barrueco-Francioni, J., Arias-Verdú, D., Lozano-Saez, R., Quesada-Garcia, G., Seller-Pérez, G., Figueiredo, A., Anzola, Y., Pereira, R., Bento, L., Lai, M., Deiana, M., Seller-Perez, G., Vardas, K., Ilia, S., Sertedaki, A., Charmadari, E., Stratakis, C. A., Briassouli, E., Goukos, D., Psarra, K., Botoula, E., Tsagarakis, S., Mageira, E., Routsi, C., Nanas, S., Campello, E., Radu, C. M., Su, H., Lam, Y. M., Willis, K., Pullar, V., Hubner, R. P., Tsang, J. L., de Guadiana-Romualdo, L. García, Rebollo-Acebes, S., Esteban-Torrella, P., Jiménez-Sánchez, R., Jiménez-Santos, E., Ortín-Freire, A., Hernando-Holgado, A., Albaladejo-Otón, M. D., Coelho, L., Rabello, L., Póvoa, P., Varis, E., Poukkanen, M., Jacob, S., Takala, J., Wilkman, E., Lundberg, O. H. M., Bergenzaun, L., Rydén, J., Rosenqvist, M., Melander, O., Chew, M. S., Kishihara, Y., Yasuda, H., Jimenez, R., Torrella, P. Esteban, Fernandez, A., Sanchez, S., Ortin, A., Prats, R. Guillamat, Aguilera, E., Marti, D., Fernandez, L., Ferrer, M., Lanziotti, V. S., Pulcheri, L., Ribeiro, M. O., Barbosa, A. P., e Silva, J. R. Lapa, Soares, M., Salluh, J. I. F., Marqués, M. Gil, Moreno, A. Puppo, Pizarraya, A. Gutierrez, Diaz, J. Pachón, Smani, Y., Connell, M. Mc, Zhang, L. A., Parker, R. S., Banerjee, I., Clermont, G., Norberg, E., Oras, J., Cuisinier, A., Maufrais, C., Payen, J. F., Nottin, S., Walther, G., Arib, S., Bilotta, F., Badenes, R., Rubulotta, F., Mirek, S., Monfort, B., Stazi, E., Roig, A. Lozano, Magnoni, S., Marando, M., Pifferi, S., Conte, V., Ortolano, F., Carbonara, M., Bertani, G., Scola, E., Cadioli, M., Triulzi, F., Colombo, A., Stocchetti, N., Rotzel, H. B., Lázaro, A. Serrano, Prada, D. Aguillón, Guimillo, M. Rodriguez, Piqueras, C. Sanchís, Guia, J. Romero, Simon, M. García, Arizmendi, A. Mesejo, Carratalá, A., El Maraghi, S., Yehia, A., Bakry, M., Shoman, A., Backes, F. N., Bianchin, M. M., Vieira, S. R. R., de Souza, A., Backes, A. N., Klein, C., Arunkumar, A. S., Lozano, A., Gallaher, C., Cattlin, S., Gordon, S., Picard, J., Fontana, V., Bond, O., Nobile, L., Mrozek, S., Delamarre, L., Capilla, F., Al-Saati, T., Fourcade, O., Dominguez-Berrot, A. M., Gonzalez-Vaquero, M., Vallejo-Pascual, M. E., Gupta, D., Ivory, B. D., Chopra, M., McCarthy, J., Felderhof, C. L., MacNeil, C., Maggiorini, M., Duska, F., Fumis, R. R. L., Junior, J. M. Vieira, Amarante, G., Skorko, A., Sanders, S., Aron, J., Kroll, R. J., Redfearn, C., Krishnan, P., Khalil, J. E., Kongpolprom, N., Gulia, V., Lourenço, E., Duro, C., Baptista, G., Alves, A., Arminda, B., Rodrigues, M., Hayward, J., Baldwin, F., Gray, R., Katinakis, P. A., Stijf, M., Ten Kleij, M., Jansen-Frederiks, M., Broek, R., de Bruijne, M., Spronk, P. E., Sinha, K., Luney, M., Palmer, K., Keating, L., Abu-Habsa, M., Bahl, R., Baskaralingam, N., Ahmad, A., Kanapeckaite, L., Bhatti, P., Glace, S., Jeyabraba, S., Lewis, H. F., Kostopoulos, A., Raja, M., West, A., Ely, A., Turkoglu, L. M., Zolfaghari, P., Baptista, J. P., Marques, M. P., Martins, P., Pimentel, J., Su, Y. C., Villacres, S., Stone, M. E., Parsikia, A., Medar, S., O’Dea, K. P., Porter, J., Tirlapur, N., Jonathan, J. M., Singh, S., Takata, M., McWhirter, E., Lyon, R., Hariz, M. L., Azmi, E., Alkhan, J., Movsisyan, V., Petrikov, S., Marutyan, Z., Aliev, I., Evdokimov, A., Antonucci, E., Merz, T., Hartmann, C., Calzia, E., Radermacher, P., Nußbaum, B., Huber-Lang, M., Gröger, M., Svoren-Jabalera, E., Davenport, E. E., Humburg, P., Knight, J., Hinds, C. J., Jun, I. J., Kim, W. J., Lee, E. H., Besch, G., Perrotti, A., Puyraveau, M., Baltres, M., Samain, E., Chocron, S., Pili-Floury, S., Plata-Menchaca, E. P., Sabater-Riera, J., Estruch, M., Boza, E., Toscana-Fernández, J., Bruguera-Pellicer, E., Ordoñez-Llanos, J., Pérez-Fernández, X. L., Cavaleiro, P., Tralhão, A., Arrigo, M., Lopes, J.-P., Lebrun, M., Cholley, B., PerezVela, J. L., MarinMateos, H., Rivera, J. J. Jimenez, Llorente, M. A. Alcala, De Marcos, B. Gonzalez, Fernandez, F. J. Gonzalez, Laborda, C. Garcia, Zamora, D. Fernandez, Delgado, J. C. Lopez, Imperiali, C., Dastis, M., Górka, J., Górka, K., Iwaniec, T., Frołow, M., Polok, K., Fronczek, J., Kózka, M., Musiał, J., Szczeklik, W., Sileli, M., Moursia, C., Maleoglou, H., Leleki, K., Uz, Z., Ince, Y., Papatella, R., Bulent, E., De Mol, B., Vicka, V., Gineityte, D., Ringaitiene, D., Norkiene, I., Sipylaite, J., Möller, C., Thomas-Rueddel, D. O., Vlasakov, V., Rochwerg, B., Theurer, P., Al Sibai, J. Zanabili, Camblor, P. Martinez, Fernandez, P. Alvarez, Gala, J. M. García, Guisasola, J. Silba, Tamura, T., Miyajima, I., Yamashita, K., Yokoyama, M., Dalampini, E., Nastou, M., Baddour, A., Ignatiadis, A., Asteri, T., Hathorn, K. E., Purtle, S. W., Viana, M. V., Tonietto, T. A., Gross, L. A., Costa, V. L., Tavares, A. L. J., Lisboa, B. O., Moraes, R. B., Vieira, S. R., Viana, L. V., Azevedo, M. J., Ceniccola, G. D., Pequeno, R. S. F., Holanda, T. P., Mendonça, V. S., Araújo, W. M. C., Carvalho, L. S. F., Segaran, E., Vickers, L., Brinchmann, K., Wignall, I., De Brito-Ashurst, I., del Olmo, R., Esteban, M. J., Vaquerizo, C., Carreño, R., Gálvez, V., Kaminsky, G., Nieto, B., Fuentes, M., De la Torre, M. A., Torres, E., Alonso, A., Velayos, C., Saldaña, T., Escribá, A., GRIP, J., Kölegård, R., Sundblad, P., Rooyackers, O., Naser, Ben, Jaziri, F., Jazia, A. Ben, Barghouth, M., Hentati, O., Skouri, W., El Euch, M., Mahfoudhi, M., Turki, S., Abdelghni, K. Ben, Abdallah, Ben, Maha, B. N. M., Lorente, M., Włudarczyk, A., Hałek, A., Bargouth, M., Bennasr, M., Abdelghani, K. Ben, Abdallah, T. Ben, Geenen, I. L., Parienti, J. J., Straaten, H. M. Oudemans-van, Shum, H. P., King, H. S., Chan, K. C., Yan, W. W., Londoño, J. Gonzalez, Cardenas, C. Lorencio, Pedrosa, M. Morales, Gubianas, C. Murcia, Bertolin, C. Fuster, Batllori, N. Vila, Sirvent, J. M., Mukhopadhyay, A., Chan, H. Y., Kowitlawakul, Y., Remani, D., Leong, C. S. F., Henry, C. J., Puthucheary, Z. A., Mendsaikhan, N., Begzjav, T., Lundeg, G., Dünser, M., Welsh, S. P., Guerra, E., Zerpa, M. C. l., Zechner, F., Berdaguer, F., Risso-Vazquez, A., Masevicius, F. D., Greaney, D., Magee, A., Fitzpatrick, G., Lugo-Cob, R. G., Tejeda-Huezo, B. C., Cano-Oviedo, A. A., Aydogan, M. S., Togal, T., Taha, A., Chai, H. Z., Kam, C., Razali, S. S. Yang, Sivasamy, V., Kuan, L. Y., Morales, M. A. Lopez, Pires, T., and Azevedo, L. C. P.

Subjects
Meeting Abstracts
Abstract

Introduction In addition to systemic hemodynamics, the management\ud of neurocritically ill patients is often informed by neuromonitoring. In\ud the absence of high-level evidence clinicians are often guided by personal\ud and local expertise. Little is known about practices as they pertain\ud to the use of such monitoring in patients with acute brain injury (ABI).\ud Objectives To investigate practices in bedside monitoring for ABI patients.\ud Particularly interested in differences among “neurointensivists”\ud (NIs; defined here as intensivists whose clinical practice is comprised\ud > 1/3 by neurocritical care) and other intensivists (OIs). Also, to\ud explore patterns specific to traumatic brain injury (TBI) and subarachnoid\ud hemorrhage (SAH), as well as preferences and availability of\ud particular technologies/devices.\ud Methods Electronic survey of 22 items including two case-based scenarios;\ud endorsed by SCCM (9,000 recipients) and ESICM (on-line\ud newsletter) in 2013. A sample size of 370 was calculated based on a\ud population of 10,000 physician members, a 5 % margin error, and\ud 95 % confidence interval. We summarized results using descriptive\ud statistics (proportions with 95 % confidence intervals). A chi-square\ud test was used to compare proportions of responses between NIs and\ud OIs with a significance p < 0.05.\ud Results There were 655 responders (66 % completion rate); 422(65 %)\ud were classified as OIs and 226(35 %) as NIs. More NIs follow\ud hemodynamic protocols for neurocritically-ill patients (56 % vs. 43 %, p\ud 0.001), in TBI (44.5 % vs. 33.3 %, p 0.007), and in SAH (38.1 % vs. 21.3 %,\ud p < 000.1). For delayed cerebral ischemia (DCI), more NIs target cardiac\ud index (CI) (35 % vs. 21 %, p 0.0001), and fluid responsiveness (62 % vs.\ud 53 %, p 0.03), use more bedside ultrasound (BUS) (42 % vs. 29 %, p\ud 0.005) and arterial waveform analysis (40 % vs. 29 %, p 0.02). For DCI\ud neuromonitoring, NIs use more angiography (57 % vs. 43 %, p 0.004),\ud TCD (46 % vs. 38 %, p 0.0001), and CTP (32 % vs.16 %, p 0.0001). For\ud CPP optimization in TBI, NIs use more arterial waveform analysis (45 %\ud vs. 35 %, p 0.019), and BUS (37 % vs. 27.7 %, p 0.023), while more OIs\ud monitor mixed venous oxygen saturation (54.1 % vs. 45 %, p 0.045). For\ud TBI neuromonitoring, NIs use more PbtO2 (28 % vs. 10 %, p 0.0001). In\ud the case scenario of raised ICP/low PbtO2, most employ analgosedation\ud (47 %) and osmotherapy (38 %). Fewer make use of preserved pressure\ud reactivity, particularly OIs (vasopressor use 23 % vs. 34 %, p 0.014).\ud Conclusions There is large heterogeneity in the use of monitoring protocols,\ud variables, and technologies/devices. “Neurointensivists” not only\ud employ more neuromonitoring but also more hemodynamic monitoring\ud in patients with acute brain injury. ICP/CPP remain the most commonly\ud followed neuro-variables in TBI patients, with low use of other\ud brain-physiology parameters, sugg

Published
2016

49. What works for wellbeing in culture and sport? Report of a DELPHI process to support coproduction and establish principles and parameters of an evidence review

Author

Daykin, N, Mansfield, L, Payne, A, Kay, T, Meads, C, DInnocenzo, G, Burnett, A, Dolan, P, Julier, G, Longworth, L, Tomlinson, A, Testoni, S, and Victor, C

Subjects
Delphi Technique, Public Health Systems Research, coproduction, Health Policy, Health Status, United Kingdom, culture, Humanities, wellbeing, evidence review, Surveys and Questionnaires, HN Social history and conditions. Social problems. Social reform, Humans, sport, DELPHI, Sports
Abstract

Aims: There is a growing recognition of the ways in which culture and sport can contribute to wellbeing. A strong evidence base is needed to support innovative service development and a 3-year research programme is being undertaken to capture best evidence of wellbeing impacts and outcomes of cultural and sporting activities in order to inform UK policy and practice. This article provides an overview of methods and findings from an initial coproduction process with key stakeholders that sought to explore and agree principles and parameters of the evidence review for culture, sport and wellbeing (CSW). Methods: A two-stage DELPHI process was conducted with a purposeful sample of 57 stakeholders between August and December 2015. Participants were drawn from a range of culture and sport organisations and included commissioners and managers, policy makers, representatives of service delivery organisations (SDOs) and scholars. The DELPHI 1 questionnaire was developed from extensive consultation in July and August 2015. It explored definitions of wellbeing, the role of evidence, quality assessment, and the culture and sport populations, settings and interventions that are most likely to deliver wellbeing outcomes. Following further consultation, the results, presented as a series of ranked statements, were sent back to participants (DELPHI 2), which allowed them to reflect on and, if they wished, express agreement or disagreement with the emerging consensus. Results: A total of 40 stakeholders (70.02%) responded to the DELPHI questionnaires. DELPHI 1 mapped areas of agreement and disagreement, confirmed in DELPHI 2. The exercise drew together the key priorities for the CSW evidence review. Conclusion: The DELPHI process, in combination with face-to-face deliberation, enabled stakeholders to engage in complex discussion and express nuanced priorities while also allowing the group to come to an overall consensus and agree outcomes. The results will inform the CSW evidence review programme until its completion in March 2018.

Published
2016

50. A systematic overview of reviews of the effectiveness and cost effectiveness of interventions to promote healthy lifestyle behaviours in people living with or beyond cancer

Author

Mansfield, L, O'Connell, N, Kay, T, Fortune, J, Kanya, L, Grigsby-Duffy, L, Fox-Rushby, J, and Meads, C

Subjects
Smoking, Physical Activity, Lifestyle, Alcohol, Cancer, Nutrition
Abstract

An overview of systematic reviews synthesised evidence on the relationship between smoking, physical activity, dietary behaviours and alcohol consumption and important outcomes for people living with and beyond cancer. That review demonstrated that some lifestyle behaviours may be associated with important outcomes in people living with and beyond cancer (PLWBC). However it did not inform us of whether specifically delivering interventions aimed at modifying lifestyle behaviours effectively improve outcomes for PLWBC. How to promote and sustain healthy lifestyle behaviours in cancer populations is not well understood. A single, overarching summary of evidence from published systematic reviews of lifestyle interventions which compares and contrasts findings can provide policy and practice professionals with the evidence needed for more effective decision making. This overview of systematic reviews provides a synthesis of evidence on the effectiveness and cost-effectiveness of interventions aimed at altering lifestyle behaviours for improving outcomes for people living with and beyond cancer.

Published
2016

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