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49 results on '"Mannami, Tomohiko"'

1. Long-term outcomes of patients with primary intestinal follicular lymphoma managed with watch-and-wait strategy

Author

Iwamuro, Masaya, Tanaka, Takehiro, Ennishi, Daisuke, Matsueda, Kazuhiro, Yoshioka, Masao, Miyahara, Koji, Sakaguchi, Chihiro, Nishimura, Mamoru, Nagahara, Teruya, Mannami, Tomohiko, Takenaka, Ryuta, Oka, Shohei, Inoue, Masafumi, Takimoto, Hidetaka, Inaba, Tomoki, Kobayashi, Sayo, Toyokawa, Tatsuya, Tsugeno, Hirofumi, Suzuki, Seiyuu, Sawada, Sachiko, Tanaka, Shouichi, Tsuzuki, Takao, and Okada, Hiroyuki

Published
2023
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2. Efficacy of polyglycolic acid sheeting with fibrin glue for perforations related to gastrointestinal endoscopic procedures: a multicenter retrospective cohort study

Author

Takimoto, Kengo, Matsuura, Noriko, Nakano, Yoshiko, Tsuji, Yosuke, Takizawa, Kohei, Morita, Yoshinori, Nagami, Yasuaki, Hirasawa, Kingo, Araki, Hiroshi, Yamaguchi, Naoyuki, Aoyagi, Hiroyuki, Matsuhashi, Tamotsu, Iizuka, Toshiro, Saegusa, Hisanobu, Yamazaki, Kenji, Hori, Shinichiro, Mannami, Tomohiko, Hanaoka, Noboru, Mori, Hirohito, Kobara, Hideki, Takeuchi, Yoji, and Ono, Hiroyuki

Published
2022
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3. A genome-wide association study identified PTPN2 as a population-specific susceptibility gene locus for primary biliary cholangitis

Author

Hitomi, Yuki, primary, Ueno, Kazuko, additional, Aiba, Yoshihiro, additional, Nishida, Nao, additional, Kono, Michihiro, additional, Sugihara, Mitsuki, additional, Kawai, Yosuke, additional, Kawashima, Minae, additional, Khor, Seik-Soon, additional, Sugi, Kazuhiro, additional, Kouno, Hirotaka, additional, Kouno, Hiroshi, additional, Naganuma, Atsushi, additional, Iwamoto, Satoru, additional, Katsushima, Shinji, additional, Furuta, Kiyoshi, additional, Nikami, Toshiki, additional, Mannami, Tomohiko, additional, Yamashita, Tsutomu, additional, Ario, Keisuke, additional, Komatsu, Tatsuji, additional, Makita, Fujio, additional, Shimada, Masaaki, additional, Hirashima, Noboru, additional, Yokohama, Shiro, additional, Nishimura, Hideo, additional, Sugimoto, Rie, additional, Komura, Takuya, additional, Ota, Hajime, additional, Kojima, Motoyuki, additional, Nakamuta, Makoto, additional, Fujimori, Naoyuki, additional, Yoshizawa, Kaname, additional, Mano, Yutaka, additional, Takahashi, Hironao, additional, Hirooka, Kana, additional, Tsuruta, Satoru, additional, Sato, Takeaki, additional, Yamasaki, Kazumi, additional, Kugiyama, Yuki, additional, Motoyoshi, Yasuhide, additional, Suehiro, Tomoyuki, additional, Saeki, Akira, additional, Matsumoto, Kosuke, additional, Nagaoka, Shinya, additional, Abiru, Seigo, additional, Yatsuhashi, Hiroshi, additional, Ito, Masahiro, additional, Kawata, Kazuhito, additional, Takaki, Akinobu, additional, Arai, Kuniaki, additional, Arinaga, Teruko, additional, Abe, Masanori, additional, Harada, Masaru, additional, Taniai, Makiko, additional, Zeniya, Mikio, additional, Ohira, Hiromasa, additional, Shimoda, Shinji, additional, Komori, Atsumasa, additional, Tanaka, Atsushi, additional, Ishigaki, Kazuyoshi, additional, Nagasaki, Masao, additional, Tokunaga, Katsushi, additional, and Nakamura, Minoru, additional

Published
2024
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5. Nonrecurrence Rate of Underwater EMR for ≤20-mm Nonampullary Duodenal Adenomas: A Multicenter Prospective Study (D-UEMR Study)

Author

Kanzaki, Hiromitsu, Inoue, Shuntaro, Miyake, Muneaki, Ohmori, Masayasu, Takeuchi, Yoji, Tani, Yasuhiro, Harada, Nobuyuki, Agatsuma, Nobukazu, Okada, Keijirou, Ikenouchi, Maiko, Nakatani, Yasuki, Uenoyama, Yoshito, Yamashita, Yukitaka, Ishikawa, Shigenao, Inaba, Tomoki, Miyahara, Koji, Moritou, Yuki, Nakagawa, Masahiro, Kitae, Hiroaki, Ishida, Tsugitaka, Naito, Yuji, Nishio, Akiyoshi, Shimatani, Masaaki, Kato, Ryo, Taki, Shinya, Mandai, Koichiro, Sanada, Kasumi, Nakase, Kojiro, Nebiki, Hiroko, Saito, Shunsuke, Wakatsuki, Toshiyuki, Nishimura, Naoyuki, Yamasaki, Yasushi, Uedo, Noriya, Akamatsu, Takuji, Kagawa, Tomo, Higashi, Reiji, Dohi, Osamu, Furukawa, Masanori, Takahashi, Yu, Inoue, Takuya, Tanaka, Shouichi, Takenaka, Ryuta, Iguchi, Mikitaka, Kawamura, Takuji, Tsuzuki, Takao, Yamasaki, Tomoaki, Yamashina, Takeshi, Nasu, Junichiro, Mannami, Tomohiko, Yamauchi, Atsushi, Matsueda, Kazuhiro, Aizawa, Shigeyuki, Mitsuhashi, Toshiharu, and Okada, Hiroyuki

Published
2022
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6. Continuous warfarin administration versus heparin bridging therapy in post colorectal polypectomy haemorrhage: a study protocol for a multicentre randomised controlled trial (WHICH study)

Author

Nagami, Yasuaki, Sakai, Taishi, Yamamura, Masafumi, Nakatani, Masami, Katsuno, Takayuki, Suekane, Takehisa, Uno, Hironori, Minamino, Hiroaki, Okuyama, Masatsugu, Okamoto, Junichi, Kumamoto, Mitsutaka, Noguchi, Atsushi, Yamamori, Kazuki, Takaishi, Osamu, Ochi, Masahiro, Miyazaki, Takako, Tsuji, Shigetsugu, Ikehara, Hisatomo, Kawaguchi, Koichiro, Hayashi, Tomoyuki, Mannami, Tomohiko, Kakimoto, Kazuki, Naito, Yoshihide, Hashimoto, Satoru, Li, Zhaoliang, Komeda, Yoriaki, Kishino, Takaaki, Yamamoto, Yoshinobu, Iguchi, Mikitaka, Akamatsu, Takuji, Horii, Toshiki, Miura, Ko, Yamashina, Takeshi, Sugihara, Yuusaku, Watanabe, Noboru, Kiyotoki, Shu, Fujii, Ryoji, Murata, Masaki, Ono, Satoshi, Narasaka, Toshiaki, Kitamura, Shinji, Kono, Mitsuhiro, Kato, Motohiko, Kawaratani, Hideto, Tanaka, Kyosuke, Yaoita, Takao, Yamaguchi, Shinjiro, Abe, Keiichiro, Kawamura, Takuji, Kinoshita, Yosuke, Imai, Kenichiro, Fujinami, Haruka, Yada, Tomoyuki, Miyamoto, Hayato, Yoshida, Hisako, and Fujiwara, Yasuhiro

Published
2021
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7. Nationwide multicenter study on adverse events associated with a patency capsule: Additional survey of appropriate use of patency capsule study.

Author

Omori, Teppei, Ohmiya, Naoki, Watanabe, Kenji, Hirai, Fumihito, Nakamura, Masanao, Kitamura, Kazuya, Ozeki, Keiji, Oka, Shiro, Kawano, Seiji, Handa, Osamu, Kawai, Mikio, Ninomiya, Kazeo, Sagawa, Tamotsu, Wakamatsu, Takahiro, Araki, Akihiro, Koike, Yuji, Kato, Shingo, Hashimoto, Shinichi, Mannami, Tomohiko, and Nakaji, Konosuke

Subjects
CROHN'S disease, RADIO frequency identification systems, SMALL intestine, BOWEL obstructions, ABDOMINAL pain
Abstract

Background and Aim: The PillCam patency capsule (PC) without a radio frequency identification tag was released to preclude retention of the small bowel capsule endoscope (CE) in Japan in 2012. We conducted a multicenter study to determine tag‐less PC‐related adverse events (AEs). Methods: We first conducted a retrospective survey using a standardized data collection sheet for the clinical characteristics of PC‐related AEs among 1096 patients collected in a prospective survey conducted between January 2013 and May 2014 (Cohort 1). Next, we retrospectively investigated additional AEs that occurred before and after Cohort 1 within the period June 2012 and December 2014 among 1482 patients (Cohort 2). Results: Of the 2578 patients who underwent PC examinations from both cohorts, 74 AEs occurred among 61 patients (2.37%). The main AEs were residual parylene coating in 25 events (0.97%), PC‐induced small bowel obstruction, suspicious of impaction, in 23 events (0.89%), and CE retention even after patency confirmation in 10 events (0.39%). Residual parylene coating was significantly associated with Crohn's disease (P < 0.01). Small bowel obstruction was significantly associated with physicians with less than 1 year of experience handling the PC and previous history of postprandial abdominal pain (P < 0.01 and P < 0.03, respectively). CE retention was ascribed to erroneous judgment of PC localization in all cases. Conclusions: This large‐scale multicenter study provides evidence supporting the safety and efficiency of a PC to preclude CE retention. Accurate PC localization in patients without excretion and confirmation of previous history of postprandial abdominal pain before PC examinations is warranted (UMIN000010513). [ABSTRACT FROM AUTHOR]

Published
2024
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9. Glasgow‐Blatchford score combined with nasogastric aspirate as a new diagnostic algorithm for patients with nonvariceal upper gastrointestinal bleeding

Author

Wakatsuki, Toshiyuki, primary, Mannami, Tomohiko, additional, Furutachi, Shinichi, additional, Numoto, Hiroki, additional, Umekawa, Tsuyoshi, additional, Mitsumune, Mayu, additional, Sakaki, Tsukasa, additional, Nagahara, Hanako, additional, Fukumoto, Yasushi, additional, Yorifuji, Takashi, additional, and Shimizu, Shin'ichi, additional

Published
2022
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12. Nonrecurrence Rate of Underwater EMR for ≤20-mm Nonampullary Duodenal Adenomas: A Multicenter Prospective Study (D-UEMR Study)

Author

Yamasaki, Yasushi, primary, Uedo, Noriya, additional, Akamatsu, Takuji, additional, Kagawa, Tomo, additional, Higashi, Reiji, additional, Dohi, Osamu, additional, Furukawa, Masanori, additional, Takahashi, Yu, additional, Inoue, Takuya, additional, Tanaka, Shouichi, additional, Takenaka, Ryuta, additional, Iguchi, Mikitaka, additional, Kawamura, Takuji, additional, Tsuzuki, Takao, additional, Yamasaki, Tomoaki, additional, Yamashina, Takeshi, additional, Nasu, Junichiro, additional, Mannami, Tomohiko, additional, Yamauchi, Atsushi, additional, Matsueda, Kazuhiro, additional, Aizawa, Shigeyuki, additional, Mitsuhashi, Toshiharu, additional, Okada, Hiroyuki, additional, Kanzaki, Hiromitsu, additional, Inoue, Shuntaro, additional, Miyake, Muneaki, additional, Ohmori, Masayasu, additional, Takeuchi, Yoji, additional, Tani, Yasuhiro, additional, Harada, Nobuyuki, additional, Agatsuma, Nobukazu, additional, Okada, Keijirou, additional, Ikenouchi, Maiko, additional, Nakatani, Yasuki, additional, Uenoyama, Yoshito, additional, Yamashita, Yukitaka, additional, Ishikawa, Shigenao, additional, Inaba, Tomoki, additional, Miyahara, Koji, additional, Moritou, Yuki, additional, Nakagawa, Masahiro, additional, Kitae, Hiroaki, additional, Ishida, Tsugitaka, additional, Naito, Yuji, additional, Nishio, Akiyoshi, additional, Shimatani, Masaaki, additional, Kato, Ryo, additional, Taki, Shinya, additional, Mandai, Koichiro, additional, Sanada, Kasumi, additional, Nakase, Kojiro, additional, Nebiki, Hiroko, additional, Saito, Shunsuke, additional, Wakatsuki, Toshiyuki, additional, and Nishimura, Naoyuki, additional

Published
2022
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13. Corrigendum to ‘An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs’ [J Hepatol 2021;75(3):572–581]

Author

Cordell, Heather J., primary, Fryett, James J., additional, Ueno, Kazuko, additional, Darlay, Rebecca, additional, Aiba, Yoshihiro, additional, Hitomi, Yuki, additional, Kawashima, Minae, additional, Nishida, Nao, additional, Khor, Seik-Soon, additional, Gervais, Olivier, additional, Kawai, Yosuke, additional, Nagasaki, Masao, additional, Tokunaga, Katsushi, additional, Tang, Ruqi, additional, Shi, Yongyong, additional, Li, Zhiqiang, additional, Juran, Brian D., additional, Atkinson, Elizabeth J., additional, Gerussi, Alessio, additional, Carbone, Marco, additional, Asselta, Rosanna, additional, Cheung, Angela, additional, de Andrade, Mariza, additional, Baras, Aris, additional, Horowitz, Julie, additional, Ferreira, Manuel A.R., additional, Sun, Dylan, additional, Jones, David E., additional, Flack, Steven, additional, Spicer, Ann, additional, Mulcahy, Victoria L., additional, Byun, Jinyoung, additional, Han, Younghun, additional, Sandford, Richard N., additional, Lazaridis, Konstantinos N., additional, Amos, Christopher I., additional, Hirschfield, Gideon M., additional, Seldin, Michael F., additional, Invernizzi, Pietro, additional, Siminovitch, Katherine A., additional, Ma, Xiong, additional, Nakamura, Minoru, additional, Mells, George F., additional, Mason, Andrew, additional, Vincent, Catherine, additional, Xie, Gang, additional, Zhang, Jinyi, additional, Affronti, Andrea, additional, Almasio, Piero L., additional, Alvaro, Domenico, additional, Andreone, Pietro, additional, Andriulli, Angelo, additional, Azzaroli, Francesco, additional, Battezzati, Pier Maria, additional, Benedetti, Antonio, additional, Bragazzi, MariaConsiglia, additional, Brunetto, Maurizia, additional, Bruno, Savino, additional, Calvaruso, Vincenza, additional, Cardinale, Vincenzo, additional, Casella, Giovanni, additional, Cazzagon, Nora, additional, Ciaccio, Antonio, additional, Coco, Barbara, additional, Colli, Agostino, additional, Colloredo, Guido, additional, Colombo, Massimo, additional, Colombo, Silvia, additional, Cristoferi, Laura, additional, Cursaro, Carmela, additional, Crocè, Lory Saveria, additional, Crosignani, Andrea, additional, D’Amato, Daphne, additional, Donato, Francesca, additional, Elia, Gianfranco, additional, Fabris, Luca, additional, Fagiuoli, Stefano, additional, Ferrari, Carlo, additional, Floreani, Annarosa, additional, Galli, Andrea, additional, Giannini, Edoardo, additional, Grattagliano, Ignazio, additional, Lampertico, Pietro, additional, Lleo, Ana, additional, Malinverno, Federica, additional, Mancuso, Clara, additional, Marra, Fabio, additional, Marzioni, Marco, additional, Massironi, Sara, additional, Mattalia, Alberto, additional, Miele, Luca, additional, Milani, Chiara, additional, Morini, Lorenzo, additional, Morisco, Filomena, additional, Muratori, Luigi, additional, Muratori, Paolo, additional, Niro, Grazia A., additional, O’Donnell, Sarah, additional, Picciotto, Antonio, additional, Portincasa, Piero, additional, Rigamonti, Cristina, additional, Ronca, Vincenzo, additional, Rosina, Floriano, additional, Spinzi, Giancarlo, additional, Strazzabosco, Mario, additional, Tarocchi, Mirko, additional, Tiribelli, Claudio, additional, Toniutto, Pierluigi, additional, Valenti, Luca, additional, Vinci, Maria, additional, Zuin, Massimo, additional, Nakamura, Hitomi, additional, Abiru, Seigo, additional, Nagaoka, Shinya, additional, Komori, Atsumasa, additional, Yatsuhashi, Hiroshi, additional, Ishibashi, Hiromi, additional, Ito, Masahiro, additional, Migita, Kiyoshi, additional, Ohira, Hiromasa, additional, Katsushima, Shinji, additional, Naganuma, Atsushi, additional, Sugi, Kazuhiro, additional, Komatsu, Tatsuji, additional, Mannami, Tomohiko, additional, Matsushita, Kouki, additional, Yoshizawa, Kaname, additional, Makita, Fujio, additional, Nikami, Toshiki, additional, Nishimura, Hideo, additional, Kouno, Hiroshi, additional, Kouno, Hirotaka, additional, Ota, Hajime, additional, Komura, Takuya, additional, Nakamura, Yoko, additional, Shimada, Masaaki, additional, Hirashima, Noboru, additional, Komeda, Toshiki, additional, Ario, Keisuke, additional, Nakamuta, Makoto, additional, Yamashita, Tsutomu, additional, Furuta, Kiyoshi, additional, Kikuchi, Masahiro, additional, Naeshiro, Noriaki, additional, Takahashi, Hironao, additional, Mano, Yutaka, additional, Tsunematsu, Seiji, additional, Yabuuchi, Iwao, additional, Shimada, Yusuke, additional, Yamauchi, Kazuhiko, additional, Sugimoto, Rie, additional, Sakai, Hironori, additional, Mita, Eiji, additional, Koda, Masaharu, additional, Tsuruta, Satoru, additional, Kamitsukasa, Hiroshi, additional, Sato, Takeaki, additional, Masaki, Naohiko, additional, Kobata, Tatsuro, additional, Fukushima, Nobuyoshi, additional, Ohara, Yukio, additional, Muro, Toyokichi, additional, Takesaki, Eiichi, additional, Takaki, Hitoshi, additional, Yamamoto, Tetsuo, additional, Kato, Michio, additional, Nagaoki, Yuko, additional, Hayashi, Shigeki, additional, Ishida, Jinya, additional, Watanabe, Yukio, additional, Kobayashi, Masakazu, additional, Koga, Michiaki, additional, Saoshiro, Takeo, additional, Yagura, Michiyasu, additional, Hirata, Keisuke, additional, Tanaka, Atsushu, additional, Takikawa, Hajime, additional, Zeniya, Mikio, additional, Abe, Masanori, additional, Onji, Morikazu, additional, Kaneko, Shuichi, additional, Honda, Masao, additional, Arai, Kuniaki, additional, Arinaga-Hino, Teruko, additional, Hashimoto, Etsuko, additional, Taniai, Makiko, additional, Umemura, Takeji, additional, Joshita, Satoru, additional, Nakao, Kazuhiko, additional, Ichikawa, Tatsuki, additional, Shibata, Hidetaka, additional, Yamagiwa, Satoshi, additional, Seike, Masataka, additional, Honda, Koichi, additional, Sakisaka, Shotaro, additional, Takeyama, Yasuaki, additional, Harada, Masaru, additional, Senju, Michio, additional, Yokosuka, Osamu, additional, Kanda, Tatsuo, additional, Ueno, Yoshiyuki, additional, Kikuchi, Kentaro, additional, Ebinuma, Hirotoshi, additional, Himoto, Takashi, additional, Yasunami, Michio, additional, Murata, Kazumoto, additional, Mizokami, Masashi, additional, Kawata, Kazuhito, additional, Shimoda, Shinji, additional, Miyake, Yasuhiro, additional, Takaki, Akinobu, additional, Yamamoto, Kazuhide, additional, Hirano, Katsuji, additional, Ichida, Takafumi, additional, Ido, Akio, additional, Tsubouchi, Hirohito, additional, Chayama, Kazuaki, additional, Harada, Kenichi, additional, Nakanuma, Yasuni, additional, Maehara, Yoshihiko, additional, Taketomi, Akinobu, additional, Shirabe, Ken, additional, Soejima, Yuji, additional, Mori, Akira, additional, Yagi, Shintaro, additional, Uemoto, Shinji, additional, H, Egawa, additional, Tanaka, Tomohiro, additional, Yamashiki, Noriyo, additional, Tamura, Sumito, additional, Sugawara, Yasuhiro, additional, Kokudo, Norihiro, additional, Chalasani, Naga, additional, Luketic, Vel, additional, Odin, Joseph, additional, Chopra, Kapil, additional, Abecasis, Goncalo, additional, Cantor, Michael, additional, Coppola, Giovanni, additional, Economides, Aris, additional, Lotta, Luca A., additional, Overton, John D., additional, Reid, Jeffrey G., additional, Shuldiner, Alan, additional, Beechert, Christina, additional, Forsythe, Caitlin, additional, Fuller, Erin D., additional, Gu, Zhenhua, additional, Lattari, Michael, additional, Lopez, Alexander, additional, Schleicher, Thomas D., additional, Padilla, Maria Sotiropoulos, additional, Toledo, Karina, additional, Widom, Louis, additional, Wolf, Sarah E., additional, Pradhan, Manasi, additional, Manoochehri, Kia, additional, Ulloa, Ricardo H., additional, Bai, Xiaodong, additional, Balasubramanian, Suganthi, additional, Barnard, Leland, additional, Blumenfeld, Andrew, additional, Eom, Gisu, additional, Habegger, Lukas, additional, Hawes, Alicia, additional, Khalid, Shareef, additional, Maxwell, Evan K., additional, Salerno, William, additional, Staples, Jeffrey C., additional, Jones, Marcus B., additional, Mitnaul, Lyndon J., additional, Sturgess, Richard, additional, Healey, Christopher, additional, Yeoman, Andrew, additional, Gunasekera, Anton VJ., additional, Kooner, Paul, additional, Kapur, Kapil, additional, Sathyanarayana, V., additional, Kallis, Yiannis, additional, Subhani, Javaid, additional, Harvey, Rory, additional, McCorry, Roger, additional, Rooney, Paul, additional, Ramanaden, David, additional, Evans, Richard, additional, Mathialahan, Thiriloganathan, additional, Gasem, Jaber, additional, Shorrock, Christopher, additional, Bhalme, Mahesh, additional, Southern, Paul, additional, Tibble, Jeremy A., additional, Gorard, David A., additional, Jones, Susan, additional, Mells, George, additional, Mulcahy, Victoria, additional, Srivastava, Brijesh, additional, Foxton, Matthew R., additional, Collins, Carole E., additional, Elphick, David, additional, Karmo, Mazn, additional, Porras-Perez, Francisco, additional, Mendall, Michael, additional, Yapp, Tom, additional, Patel, Minesh, additional, Ede, Roland, additional, Sayer, Joanne, additional, Jupp, James, additional, Fisher, Neil, additional, Carter, Martyn J., additional, Koss, Konrad, additional, Shah, Jayshri, additional, Piotrowicz, Andrzej, additional, Scott, Glyn, additional, Grimley, Charles, additional, Gooding, Ian R., additional, Williams, Simon, additional, Tidbury, Judith, additional, Lim, Guan, additional, Cheent, Kuldeep, additional, Levi, Sass, additional, Mansour, Dina, additional, Beckley, Matilda, additional, Hollywood, Coral, additional, Wong, Terry, additional, Marley, Richard, additional, Ramage, John, additional, Gordon, Harriet M., additional, Ridpath, Jo, additional, Ngatchu, Theodore, additional, Bob Grover, Vijay Paul, additional, Shidrawi, Ray G., additional, Abouda, George, additional, Corless, L., additional, Narain, Mark, additional, Rees, Ian, additional, Brown, Ashley, additional, Taylor-Robinson, Simon, additional, Wilkins, Joy, additional, Grellier, Leonie, additional, Banim, Paul, additional, Das, Debasish, additional, Heneghan, Michael A., additional, Curtis, Howard, additional, Matthews, Helen C., additional, Mohammed, Faiyaz, additional, Aldersley, Mark, additional, Srirajaskanthan, Raj, additional, Walker, Giles, additional, McNair, Alistair, additional, Sharif, Amar, additional, Sen, Sambit, additional, Bird, George, additional, Prince, Martin I., additional, Prasad, Geeta, additional, Kitchen, Paul, additional, Barnardo, Adrian, additional, Oza, Chirag, additional, Sivaramakrishnan, Nurani N., additional, Gupta, Prakash, additional, Shah, Amir, additional, Evans, Chris DJ., additional, Saha, Subrata, additional, Pollock, Katharine, additional, Bramley, Peter, additional, Mukhopadhya, Ashis, additional, Barclay, Stephen T., additional, McDonald, Natasha, additional, Bathgate, Andrew J., additional, Palmer, Kelvin, additional, Dillon, John F., additional, Rushbrook, Simon M., additional, Przemioslo, Robert, additional, McDonald, Chris, additional, Millar, Andrew, additional, Tai, Cheh, additional, Mitchell, Stephen, additional, Metcalf, Jane, additional, Shaukat, Syed, additional, Ninkovic, Mary, additional, Shmueli, Udi, additional, Davis, Andrew, additional, Naqvi, Asifabbas, additional, Lee, Tom JW., additional, Ryder, Stephen, additional, Collier, Jane, additional, Klass, Howard, additional, Cramp, Matthew E., additional, Sharer, Nichols, additional, Aspinall, Richard, additional, Ghosh, Deb, additional, Douds, Andrew C., additional, Booth, Jonathan, additional, Williams, Earl, additional, Hussaini, Hyder, additional, Christie, John, additional, Mann, Steven, additional, Thorburn, Douglas, additional, Marshall, Aileen, additional, Patanwala, Imran, additional, Ala, Aftab, additional, Maltby, Julia, additional, Matthew, Ray, additional, Corbett, Chris, additional, Vyas, Sam, additional, Singhal, Saket, additional, Gleeson, Dermot, additional, Misra, Sharat, additional, Butterworth, Jeff, additional, George, Keith, additional, Harding, Tim, additional, Douglass, Andrew, additional, Mitchison, Harriet, additional, Panter, Simon, additional, Shearman, Jeremy, additional, Bray, Gary, additional, Roberts, Michael, additional, Butcher, Graham, additional, Forton, Daniel, additional, Mahmood, Zahid, additional, Cowan, Matthew, additional, Das, Debashis, additional, Ch'ng, Chin Lye, additional, Rahman, Mesbah, additional, Whatley, Gregory C.A., additional, Wesley, Emma, additional, Mandal, Aditya, additional, Jain, Sanjiv, additional, Pereira, Stephen P., additional, Wright, Mark, additional, Trivedi, Palak, additional, Gordon, Fiona H., additional, Unitt, Esther, additional, Palejwala, Altaf, additional, Austin, Andrew, additional, Vemala, Vishwaraj, additional, Grant, Allister, additional, Higham, Andrew D., additional, Brind, Alison, additional, Mathew, Ray, additional, Cox, Mark, additional, Ramakrishnan, Subramaniam, additional, King, Alistair, additional, Whalley, Simon, additional, Fraser, Jocelyn, additional, Thomson, S.J., additional, Bell, Andrew, additional, Wong, Voi Shim, additional, Kia, Richard, additional, Gee, Ian, additional, Keld, Richard, additional, Ransford, Rupert, additional, Gotto, James, additional, and Millson, Charles, additional

Published
2021
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15. An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs

Author

Cordell, Heather J., primary, Fryett, James J., additional, Ueno, Kazuko, additional, Darlay, Rebecca, additional, Aiba, Yoshihiro, additional, Hitomi, Yuki, additional, Kawashima, Minae, additional, Nishida, Nao, additional, Khor, Seik-Soon, additional, Gervais, Olivier, additional, Kawai, Yosuke, additional, Nagasaki, Masao, additional, Tokunaga, Katsushi, additional, Tang, Ruqi, additional, Shi, Yongyong, additional, Li, Zhiqiang, additional, Juran, Brian D., additional, Atkinson, Elizabeth J., additional, Gerussi, Alessio, additional, Carbone, Marco, additional, Asselta, Rosanna, additional, Cheung, Angela, additional, de Andrade, Mariza, additional, Baras, Aris, additional, Horowitz, Julie, additional, Ferreira, Manuel A.R., additional, Sun, Dylan, additional, Jones, David E., additional, Flack, Steven, additional, Spicer, Ann, additional, Mulcahy, Victoria L., additional, Byan, Jinyoung, additional, Han, Younghun, additional, Sandford, Richard N., additional, Lazaridis, Konstantinos N., additional, Amos, Christopher I., additional, Hirschfield, Gideon M., additional, Seldin, Michael F., additional, Invernizzi, Pietro, additional, Siminovitch, Katherine A., additional, Ma, Xiong, additional, Nakamura, Minoru, additional, Mells, George F., additional, Mason, Andrew, additional, Vincent, Catherine, additional, Xie, Gang, additional, Zhang, Jinyi, additional, Affronti, Andrea, additional, Almasio, Piero L., additional, Alvaro, Domenico, additional, Andreone, Pietro, additional, Andriulli, Angelo, additional, Azzaroli, Francesco, additional, Battezzati, Pier Maria, additional, Benedetti, Antonio, additional, Bragazzi, MariaConsiglia, additional, Brunetto, Maurizia, additional, Bruno, Savino, additional, Calvaruso, Vincenza, additional, Cardinale, Vincenzo, additional, Casella, Giovanni, additional, Cazzagon, Nora, additional, Ciaccio, Antonio, additional, Coco, Barbara, additional, Colli, Agostino, additional, Colloredo, Guido, additional, Colombo, Massimo, additional, Colombo, Silvia, additional, Cristoferi, Laura, additional, Cursaro, Carmela, additional, Crocè, Lory Saveria, additional, Crosignani, Andrea, additional, D’Amato, Daphne, additional, Donato, Francesca, additional, Elia, Gianfranco, additional, Fabris, Luca, additional, Fagiuoli, Stefano, additional, Ferrari, Carlo, additional, Floreani, Annarosa, additional, Galli, Andrea, additional, Giannini, Edoardo, additional, Grattagliano, Ignazio, additional, Lampertico, Pietro, additional, Lleo, Ana, additional, Malinverno, Federica, additional, Mancuso, Clara, additional, Marra, Fabio, additional, Marzioni, Marco, additional, Massironi, Sara, additional, Mattalia, Alberto, additional, Miele, Luca, additional, Milani, Chiara, additional, Morini, Lorenzo, additional, Morisco, Filomena, additional, Muratori, Luigi, additional, Muratori, Paolo, additional, Niro, Grazia A., additional, O’Donnell, Sarah, additional, Picciotto, Antonio, additional, Portincasa, Piero, additional, Rigamonti, Cristina, additional, Ronca, Vincenzo, additional, Rosina, Floriano, additional, Spinzi, Giancarlo, additional, Strazzabosco, Mario, additional, Tarocchi, Mirko, additional, Tiribelli, Claudio, additional, Toniutto, Pierluigi, additional, Valenti, Luca, additional, Vinci, Maria, additional, Zuin, Massimo, additional, Nakamura, Hitomi, additional, Abiru, Seigo, additional, Nagaoka, Shinya, additional, Komori, Atsumasa, additional, Yatsuhashi, Hiroshi, additional, Ishibashi, Hiromi, additional, Ito, Masahiro, additional, Migita, Kiyoshi, additional, Ohira, Hiromasa, additional, Katsushima, Shinji, additional, Naganuma, Atsushi, additional, Sugi, Kazuhiro, additional, Komatsu, Tatsuji, additional, Mannami, Tomohiko, additional, Matsushita, Kouki, additional, Yoshizawa, Kaname, additional, Makita, Fujio, additional, Nikami, Toshiki, additional, Nishimura, Hideo, additional, Kouno, Hiroshi, additional, Kouno, Hirotaka, additional, Ota, Hajime, additional, Komura, Takuya, additional, Nakamura, Yoko, additional, Shimada, Masaaki, additional, Hirashima, Noboru, additional, Komeda, Toshiki, additional, Ario, Keisuke, additional, Nakamuta, Makoto, additional, Yamashita, Tsutomu, additional, Furuta, Kiyoshi, additional, Kikuchi, Masahiro, additional, Naeshiro, Noriaki, additional, Takahashi, Hironao, additional, Mano, Yutaka, additional, Tsunematsu, Seiji, additional, Yabuuchi, Iwao, additional, Shimada, Yusuke, additional, Yamauchi, Kazuhiko, additional, Sugimoto, Rie, additional, Sakai, Hironori, additional, Mita, Eiji, additional, Koda, Masaharu, additional, Tsuruta, Satoru, additional, Kamitsukasa, Hiroshi, additional, Sato, Takeaki, additional, Masaki, Naohiko, additional, Kobata, Tatsuro, additional, Fukushima, Nobuyoshi, additional, Ohara, Yukio, additional, Muro, Toyokichi, additional, Takesaki, Eiichi, additional, Takaki, Hitoshi, additional, Yamamoto, Tetsuo, additional, Kato, Michio, additional, Nagaoki, Yuko, additional, Hayashi, Shigeki, additional, Ishida, Jinya, additional, Watanabe, Yukio, additional, Kobayashi, Masakazu, additional, Koga, Michiaki, additional, Saoshiro, Takeo, additional, Yagura, Michiyasu, additional, Hirata, Keisuke, additional, Tanaka, Atsushu, additional, Takikawa, Hajime, additional, Zeniya, Mikio, additional, Abe, Masanori, additional, Onji, Morikazu, additional, Kaneko, Shuichi, additional, Honda, Masao, additional, Arai, Kuniaki, additional, Arinaga-Hino, Teruko, additional, Hashimoto, Etsuko, additional, Taniai, Makiko, additional, Umemura, Takeji, additional, Joshita, Satoru, additional, Nakao, Kazuhiko, additional, Ichikawa, Tatsuki, additional, Shibata, Hidetaka, additional, Yamagiwa, Satoshi, additional, Seike, Masataka, additional, Honda, Koichi, additional, Sakisaka, Shotaro, additional, Takeyama, Yasuaki, additional, Harada, Masaru, additional, Senju, Michio, additional, Yokosuka, Osamu, additional, Kanda, Tatsuo, additional, Ueno, Yoshiyuki, additional, Kikuchi, Kentaro, additional, Ebinuma, Hirotoshi, additional, Himoto, Takashi, additional, Yasunami, Michio, additional, Murata, Kazumoto, additional, Mizokami, Masashi, additional, Kawata, Kazuhito, additional, Shimoda, Shinji, additional, Miyake, Yasuhiro, additional, Takaki, Akinobu, additional, Yamamoto, Kazuhide, additional, Hirano, Katsuji, additional, Ichida, Takafumi, additional, Ido, Akio, additional, Tsubouchi, Hirohito, additional, Chayama, Kazuaki, additional, Harada, Kenichi, additional, Nakanuma, Yasuni, additional, Maehara, Yoshihiko, additional, Taketomi, Akinobu, additional, Shirabe, Ken, additional, Soejima, Yuji, additional, Mori, Akira, additional, Yagi, Shintaro, additional, Uemoto, Shinji, additional, H, Egawa, additional, Tanaka, Tomohiro, additional, Yamashiki, Noriyo, additional, Tamura, Sumito, additional, Sugawara, Yasuhiro, additional, Kokudo, Norihiro, additional, Chalasani, Naga, additional, Luketic, Vel, additional, Odin, Joseph, additional, Chopra, Kapil, additional, Abecasis, Goncalo, additional, Cantor, Michael, additional, Coppola, Giovanni, additional, Economides, Aris, additional, Lotta, Luca A., additional, Overton, John D., additional, Reid, Jeffrey G., additional, Shuldiner, Alan, additional, Beechert, Christina, additional, Forsythe, Caitlin, additional, Fuller, Erin D., additional, Gu, Zhenhua, additional, Lattari, Michael, additional, Lopez, Alexander, additional, Schleicher, Thomas D., additional, Padilla, Maria Sotiropoulos, additional, Toledo, Karina, additional, Widom, Louis, additional, Wolf, Sarah E., additional, Pradhan, Manasi, additional, Manoochehri, Kia, additional, Ulloa, Ricardo H., additional, Bai, Xiaodong, additional, Balasubramanian, Suganthi, additional, Barnard, Leland, additional, Blumenfeld, Andrew, additional, Eom, Gisu, additional, Habegger, Lukas, additional, Hawes, Alicia, additional, Khalid, Shareef, additional, Maxwell, Evan K., additional, Salerno, William, additional, Staples, Jeffrey C., additional, Jones, Marcus B., additional, Mitnaul, Lyndon J., additional, Sturgess, Richard, additional, Healey, Christopher, additional, Yeoman, Andrew, additional, Gunasekera, Anton VJ., additional, Kooner, Paul, additional, Kapur, Kapil, additional, Sathyanarayana, V., additional, Kallis, Yiannis, additional, Subhani, Javaid, additional, Harvey, Rory, additional, McCorry, Roger, additional, Rooney, Paul, additional, Ramanaden, David, additional, Evans, Richard, additional, Mathialahan, Thiriloganathan, additional, Gasem, Jaber, additional, Shorrock, Christopher, additional, Bhalme, Mahesh, additional, Southern, Paul, additional, Tibble, Jeremy A., additional, Gorard, David A., additional, Jones, Susan, additional, Mells, George, additional, Mulcahy, Victoria, additional, Srivastava, Brijesh, additional, Foxton, Matthew R., additional, Collins, Carole E., additional, Elphick, David, additional, Karmo, Mazn, additional, Porras-Perez, Francisco, additional, Mendall, Michael, additional, Yapp, Tom, additional, Patel, Minesh, additional, Ede, Roland, additional, Sayer, Joanne, additional, Jupp, James, additional, Fisher, Neil, additional, Carter, Martyn J., additional, Koss, Konrad, additional, Shah, Jayshri, additional, Piotrowicz, Andrzej, additional, Scott, Glyn, additional, Grimley, Charles, additional, Gooding, Ian R., additional, Williams, Simon, additional, Tidbury, Judith, additional, Lim, Guan, additional, Cheent, Kuldeep, additional, Levi, Sass, additional, Mansour, Dina, additional, Beckley, Matilda, additional, Hollywood, Coral, additional, Wong, Terry, additional, Marley, Richard, additional, Ramage, John, additional, Gordon, Harriet M., additional, Ridpath, Jo, additional, Ngatchu, Theodore, additional, Bob Grover, Vijay Paul, additional, Shidrawi, Ray G., additional, Abouda, George, additional, Corless, L., additional, Narain, Mark, additional, Rees, Ian, additional, Brown, Ashley, additional, Taylor-Robinson, Simon, additional, Wilkins, Joy, additional, Grellier, Leonie, additional, Banim, Paul, additional, Das, Debasish, additional, Heneghan, Michael A., additional, Curtis, Howard, additional, Matthews, Helen C., additional, Mohammed, Faiyaz, additional, Aldersley, Mark, additional, Srirajaskanthan, Raj, additional, Walker, Giles, additional, McNair, Alistair, additional, Sharif, Amar, additional, Sen, Sambit, additional, Bird, George, additional, Prince, Martin I., additional, Prasad, Geeta, additional, Kitchen, Paul, additional, Barnardo, Adrian, additional, Oza, Chirag, additional, Sivaramakrishnan, Nurani N., additional, Gupta, Prakash, additional, Shah, Amir, additional, Evans, Chris DJ., additional, Saha, Subrata, additional, Pollock, Katharine, additional, Bramley, Peter, additional, Mukhopadhya, Ashis, additional, Barclay, Stephen T., additional, McDonald, Natasha, additional, Bathgate, Andrew J., additional, Palmer, Kelvin, additional, Dillon, John F., additional, Rushbrook, Simon M., additional, Przemioslo, Robert, additional, McDonald, Chris, additional, Millar, Andrew, additional, Tai, Cheh, additional, Mitchell, Stephen, additional, Metcalf, Jane, additional, Shaukat, Syed, additional, Ninkovic, Mary, additional, Shmueli, Udi, additional, Davis, Andrew, additional, Naqvi, Asifabbas, additional, Lee, Tom JW., additional, Ryder, Stephen, additional, Collier, Jane, additional, Klass, Howard, additional, Cramp, Matthew E., additional, Sharer, Nichols, additional, Aspinall, Richard, additional, Ghosh, Deb, additional, Douds, Andrew C., additional, Booth, Jonathan, additional, Williams, Earl, additional, Hussaini, Hyder, additional, Christie, John, additional, Mann, Steven, additional, Thorburn, Douglas, additional, Marshall, Aileen, additional, Patanwala, Imran, additional, Ala, Aftab, additional, Maltby, Julia, additional, Matthew, Ray, additional, Corbett, Chris, additional, Vyas, Sam, additional, Singhal, Saket, additional, Gleeson, Dermot, additional, Misra, Sharat, additional, Butterworth, Jeff, additional, George, Keith, additional, Harding, Tim, additional, Douglass, Andrew, additional, Mitchison, Harriet, additional, Panter, Simon, additional, Shearman, Jeremy, additional, Bray, Gary, additional, Roberts, Michael, additional, Butcher, Graham, additional, Forton, Daniel, additional, Mahmood, Zahid, additional, Cowan, Matthew, additional, Das, Debashis, additional, Ch’ng, Chin Lye, additional, Rahman, Mesbah, additional, Whatley, Gregory C.A., additional, Wesley, Emma, additional, Mandal, Aditya, additional, Jain, Sanjiv, additional, Pereira, Stephen P., additional, Wright, Mark, additional, Trivedi, Palak, additional, Gordon, Fiona H., additional, Unitt, Esther, additional, Palejwala, Altaf, additional, Austin, Andrew, additional, Vemala, Vishwaraj, additional, Grant, Allister, additional, Higham, Andrew D., additional, Brind, Alison, additional, Mathew, Ray, additional, Cox, Mark, additional, Ramakrishnan, Subramaniam, additional, King, Alistair, additional, Whalley, Simon, additional, Fraser, Jocelyn, additional, Thomson, S.J., additional, Bell, Andrew, additional, Wong, Voi Shim, additional, Kia, Richard, additional, Gee, Ian, additional, Keld, Richard, additional, Ransford, Rupert, additional, Gotto, James, additional, and Millson, Charles, additional

Published
2021
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16. A multicenter survey of enteroscopy for the diagnosis of intestinal follicular lymphoma

Author

IWAMURO, MASAYA, OKADA, HIROYUKI, KAWANO, SEIJI, SHIODE, JUNJI, TAKENAKA, RYUTA, IMAGAWA, ATSUSHI, INABA, TOMOKI, SUZUKI, SEIYU, NISHIMURA, MAMORU, MIZUNO, MOTOWO, ARAKI, MASASHI, MANNAMI, TOMOHIKO, UEKI, TORU, KOBASHI, HARUHIKO, FUKATSU, HARUKA, TANAKA, SHOUICHI, OMOTO, AKIYOSHI, KAWAI, YOSHINARI, KITAGAWA, TAKASHI, TOYOKAWA, TATSUYA, TAKATA, KATSUYOSHI, YOSHINO, TADASHI, TAKAKI, AKINOBU, and YAMAMOTO, KAZUHIDE

Published
2015
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17. Additional file 1 of Continuous warfarin administration versus heparin bridging therapy in post colorectal polypectomy haemorrhage: a study protocol for a multicentre randomised controlled trial (WHICH study)

Author

Nagami, Yasuaki, Taishi Sakai, Yamamura, Masafumi, Nakatani, Masami, Katsuno, Takayuki, Suekane, Takehisa, Uno, Hironori, Minamino, Hiroaki, Masatsugu Okuyama, Okamoto, Junichi, Mitsutaka Kumamoto, Noguchi, Atsushi, Yamamori, Kazuki, Takaishi, Osamu, Ochi, Masahiro, Miyazaki, Takako, Shigetsugu Tsuji, Hisatomo Ikehara, Kawaguchi, Koichiro, Hayashi, Tomoyuki, Mannami, Tomohiko, Kakimoto, Kazuki, Naito, Yoshihide, Hashimoto, Satoru, Zhaoliang Li, Yoriaki Komeda, Kishino, Takaaki, Yamamoto, Yoshinobu, Mikitaka Iguchi, Akamatsu, Takuji, Horii, Toshiki, Miura, Ko, Yamashina, Takeshi, Yuusaku Sugihara, Watanabe, Noboru, Kiyotoki, Shu, Fujii, Ryoji, Murata, Masaki, Ono, Satoshi, Narasaka, Toshiaki, Kitamura, Shinji, Kono, Mitsuhiro, Kato, Motohiko, Kawaratani, Hideto, Tanaka, Kyosuke, Yaoita, Takao, Shinjiro Yamaguchi, Abe, Keiichiro, Kawamura, Takuji, Kinoshita, Yosuke, Imai, Kenichiro, Fujinami, Haruka, Yada, Tomoyuki, Miyamoto, Hayato, Yoshida, Hisako, and Fujiwara, Yasuhiro

Abstract

Additional file 1. Protocol of WHICH study ver. 7.

Published
2021
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18. Additional file 2 of Continuous warfarin administration versus heparin bridging therapy in post colorectal polypectomy haemorrhage: a study protocol for a multicentre randomised controlled trial (WHICH study)

Author

Nagami, Yasuaki, Taishi Sakai, Yamamura, Masafumi, Nakatani, Masami, Katsuno, Takayuki, Suekane, Takehisa, Uno, Hironori, Minamino, Hiroaki, Masatsugu Okuyama, Okamoto, Junichi, Mitsutaka Kumamoto, Noguchi, Atsushi, Yamamori, Kazuki, Takaishi, Osamu, Ochi, Masahiro, Miyazaki, Takako, Shigetsugu Tsuji, Hisatomo Ikehara, Kawaguchi, Koichiro, Hayashi, Tomoyuki, Mannami, Tomohiko, Kakimoto, Kazuki, Naito, Yoshihide, Hashimoto, Satoru, Zhaoliang Li, Yoriaki Komeda, Kishino, Takaaki, Yamamoto, Yoshinobu, Mikitaka Iguchi, Akamatsu, Takuji, Horii, Toshiki, Miura, Ko, Yamashina, Takeshi, Yuusaku Sugihara, Watanabe, Noboru, Kiyotoki, Shu, Fujii, Ryoji, Murata, Masaki, Ono, Satoshi, Narasaka, Toshiaki, Kitamura, Shinji, Kono, Mitsuhiro, Kato, Motohiko, Kawaratani, Hideto, Tanaka, Kyosuke, Yaoita, Takao, Shinjiro Yamaguchi, Abe, Keiichiro, Kawamura, Takuji, Kinoshita, Yosuke, Imai, Kenichiro, Fujinami, Haruka, Yada, Tomoyuki, Miyamoto, Hayato, Yoshida, Hisako, and Fujiwara, Yasuhiro

Subjects
Data_FILES
Abstract

Additional file 2. Statistical analysis plan.

Published
2021
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19. X Chromosome Contribution to the Genetic Architecture of Primary Biliary Cholangitis

Author

Asselta, Rosanna, primary, Paraboschi, Elvezia M., additional, Gerussi, Alessio, additional, Cordell, Heather J., additional, Mells, George F., additional, Sandford, Richard N., additional, Jones, David E., additional, Nakamura, Minoru, additional, Ueno, Kazuko, additional, Hitomi, Yuki, additional, Kawashima, Minae, additional, Nishida, Nao, additional, Tokunaga, Katsushi, additional, Nagasaki, Masao, additional, Tanaka, Atsushi, additional, Tang, Ruqi, additional, Li, Zhiqiang, additional, Shi, Yongyong, additional, Liu, Xiangdong, additional, Xiong, Ma, additional, Hirschfield, Gideon, additional, Siminovitch, Katherine A., additional, Carbone, Marco, additional, Cardamone, Giulia, additional, Duga, Stefano, additional, Gershwin, M. Eric, additional, Seldin, Michael F., additional, Invernizzi, Pietro, additional, Walker, Erin, additional, Xie, Gang, additional, Mason, Andy, additional, Myers, Robert, additional, Peltekian, Kevork, additional, Ghent, Cameron, additional, Atkinson, Elizabeth, additional, Juran, Bruce, additional, Lazaridis, Kostas, additional, Lu, Yue, additional, Gu, Xiangjun, additional, Jing, Kaiyan, additional, Amos, Chris, additional, Affronti, Andrea, additional, Brunetto, Maurizia, additional, Coco, Barbara, additional, Spinzi, Giancarlo, additional, Elia, Gianfranco, additional, Ferrari, Carlo, additional, Lleo, Ana, additional, Muratori, Luigi, additional, Muratori, Paolo, additional, Portincasa, Piero, additional, Colli, Agostino, additional, Bruno, Savino, additional, Colloredo, Guido, additional, Azzaroli, Francesco, additional, Andreone, Pietro, additional, Bragazzi, MariaConsiglia, additional, Alvaro, Domenico, additional, Cardinale, Vincenzo, additional, Cazzagon, Nora, additional, Rigamonti, Cristina, additional, Floreani, Annarosa, additional, Rosina, Floriano, additional, Ciaccio, Antonio, additional, Cristoferi, Laura, additional, D’Amato, Daphne, additional, Malinverno, Federica, additional, Mancuso, Clara, additional, Massironi, Sara, additional, Milani, Chiara, additional, O’Donnell, Sarah E., additional, Ronca, Vincenzo, additional, Barisani, Donatella, additional, Lampertico, Pietro, additional, Donato, Francesca, additional, Fagiuoli, Stefano, additional, Almasio, Piero L., additional, Giannini, Edoardo, additional, Cursaro, Carmela, additional, Colombo, Massimo, additional, Valenti, Luca, additional, Miele, Luca, additional, Andriulli, Angelo, additional, Niro, Grazia A., additional, Grattagliano, Ignazio, additional, Morini, Lorenzo, additional, Casella, Giovanni, additional, Vinci, Maria, additional, Battezzati, Pier Maria, additional, Crosignani, Andrea, additional, Zuin, Massimo, additional, Mattalia, Alberto, additional, Calvaruso, Vincenza, additional, Colombo, Silvia, additional, Benedetti, Antonio, additional, Marzioni, Marco, additional, Galli, Andrea, additional, Marra, Fabio, additional, Tarocchi, Mirko, additional, Picciotto, Antonio, additional, Morisco, Filomena, additional, Fabris, Luca, additional, Crocè, Lory Saveria, additional, Tiribelli, Claudio, additional, Toniutto, Pierluigi, additional, Strazzabosco, Mario, additional, Ch’ng, Chin Lye, additional, Rahman, Mesbah, additional, Yapp, Tom, additional, Sturgess, Richard, additional, Healey, Christopher, additional, Czajkowski, Marek, additional, Gunasekera, Anton, additional, Gyawali, Pranab, additional, Premchand, Purushothaman, additional, Kapur, Kapil, additional, Marley, Richard, additional, Foster, Graham, additional, Watson, Alan, additional, Dias, Aruna, additional, Subhani, Javaid, additional, Harvey, Rory, additional, McCorry, Roger, additional, Ramanaden, David, additional, Gasem, Jaber, additional, Evans, Richard, additional, Mathialahan, Thiriloganathan, additional, Shorrock, Christopher, additional, Lipscomb, George, additional, Southern, Paul, additional, Tibble, Jeremy, additional, Gorard, David, additional, Palegwala, Altaf, additional, Jones, Susan, additional, Dawwas, Mohamed, additional, Alexander, Graeme, additional, Dolwani, Sunil, additional, Prince, Martin, additional, Foxton, Matthew, additional, Elphick, David, additional, Mitchison, Harriet, additional, Gooding, Ian, additional, Karmo, Mazn, additional, Saksena, Sushma, additional, Mendall, Mike, additional, Patel, Minesh, additional, Ede, Roland, additional, Austin, Andrew, additional, Sayer, Joanna, additional, Hankey, Lorraine, additional, Hovell, Christopher, additional, Fisher, Neil, additional, Carter, Martyn, additional, Koss, Konrad, additional, Piotrowicz, Andrzej, additional, Grimley, Charles, additional, Neal, David, additional, Lim, Guan, additional, Levi, Sass, additional, Ala, Aftab, additional, Broad, Andrea, additional, Saeed, Athar, additional, Wood, Gordon, additional, Brown, Jonathan, additional, Wilkinson, Mark, additional, Gordon, Harriet, additional, Ramage, John, additional, Ridpath, Jo, additional, Ngatchu, Theodore, additional, Grover, Bob, additional, Shaukat, Syed, additional, Shidrawi, Ray, additional, Abouda, George, additional, Ali, Faiz, additional, Rees, Ian, additional, Salam, Imroz, additional, Narain, Mark, additional, Brown, Ashley, additional, Taylor-Robinson, Simon, additional, Williams, Simon, additional, Grellier, Leonie, additional, Banim, Paul, additional, Das, Debasish, additional, Chilton, Andrew, additional, Heneghan, Michael, additional, Curtis, Howard, additional, Gess, Markus, additional, Drake, Ian, additional, Aldersley, Mark, additional, Davies, Mervyn, additional, Jones, Rebecca, additional, McNair, Alastair, additional, Srirajaskanthan, Raj, additional, Pitcher, Maxton, additional, Sen, Sambit, additional, Bird, George, additional, Barnardo, Adrian, additional, Kitchen, Paul, additional, Yoong, Kevin, additional, Chirag, Oza, additional, Sivaramakrishnan, Nurani, additional, MacFaul, George, additional, Jones, David, additional, Shah, Amir, additional, Evans, Chris, additional, Saha, Subrata, additional, Pollock, Katharine, additional, Bramley, Peter, additional, Mukhopadhya, Ashis, additional, Fraser, Andrew, additional, Mills, Peter, additional, Shallcross, Christopher, additional, Campbell, Stewart, additional, Bathgate, Andrew, additional, Shepherd, Alan, additional, Dillon, John, additional, Rushbrook, Simon, additional, Przemioslo, Robert, additional, Macdonald, Christopher, additional, Metcalf, Jane, additional, Shmueli, Udi, additional, Davis, Andrew, additional, Naqvi, Asifabbas, additional, Lee, Tom, additional, Ryder, Stephen D., additional, Collier, Jane, additional, Klass, Howard, additional, Ninkovic, Mary, additional, Cramp, Matthew, additional, Sharer, Nicholas, additional, Aspinall, Richard, additional, Goggin, Patrick, additional, Ghosh, Deb, additional, Douds, Andrew, additional, Hoeroldt, Barbara, additional, Booth, Jonathan, additional, Williams, Earl, additional, Hussaini, Hyder, additional, Stableforth, William, additional, Ayres, Reuben, additional, Thorburn, Douglas, additional, Marshall, Eileen, additional, Burroughs, Andrew, additional, Mann, Steven, additional, Lombard, Martin, additional, Richardson, Paul, additional, Patanwala, Imran, additional, Maltby, Julia, additional, Brookes, Matthew, additional, Mathew, Ray, additional, Vyas, Samir, additional, Singhal, Saket, additional, Gleeson, Dermot, additional, Misra, Sharat, additional, Butterworth, Jeff, additional, George, Keith, additional, Harding, Tim, additional, Douglass, Andrew, additional, Panter, Simon, additional, Shearman, Jeremy, additional, Bray, Gary, additional, Butcher, Graham, additional, Forton, Daniel, additional, Mclindon, John, additional, Cowan, Matthew, additional, Whatley, Gregory, additional, Mandal, Aditya, additional, Gupta, Hemant, additional, Sanghi, Pradeep, additional, Jain, Sanjiv, additional, Pereira, Steve, additional, Prasad, Geeta, additional, Watts, Gill, additional, Wright, Mark, additional, Neuberger, James, additional, Gordon, Fiona, additional, Unitt, Esther, additional, Grant, Allister, additional, Delahooke, Toby, additional, Higham, Andrew, additional, Brind, Alison, additional, Cox, Mark, additional, Ramakrishnan, Subramaniam, additional, King, Alistair, additional, Collins, Carole, additional, Whalley, Simon, additional, Li, Andy, additional, Fraser, Jocelyn, additional, Bell, Andrew, additional, Wong, Voi Shim, additional, Singhal, Amit, additional, Gee, Ian, additional, Ang, Yeng, additional, Ransford, Rupert, additional, Gotto, James, additional, Millson, Charles, additional, Bowles, Jane, additional, Thomas, Caradog, additional, Harrison, Melanie, additional, Galaska, Roman, additional, Kendall, Jennie, additional, Whiteman, Jessica, additional, Lawlor, Caroline, additional, Gray, Catherine, additional, Elliott, Keith, additional, Mulvaney-Jones, Caroline, additional, Hobson, Lucie, additional, Van Duyvenvoorde, Greta, additional, Loftus, Alison, additional, Seward, Katie, additional, Penn, Ruth, additional, Maiden, Jane, additional, Damant, Rose, additional, Hails, Janeane, additional, Cloudsdale, Rebecca, additional, Silvestre, Valeria, additional, Glenn, Sue, additional, Dungca, Eleanor, additional, Wheatley, Natalie, additional, Doyle, Helen, additional, Kent, Melanie, additional, Hamilton, Caroline, additional, Braim, Delyth, additional, Wooldridge, Helen, additional, Abrahams, Rachel, additional, Paton, Alison, additional, Lancaster, Nicola, additional, Gibbins, Andrew, additional, Hogben, Karen, additional, Desousa, Phillipa, additional, Muscariu, Florin, additional, Musselwhite, Janine, additional, McKay, Alexandra, additional, Tan, LaiTing, additional, Foale, Carole, additional, Brighton, Jacqueline, additional, Flahive, Kerry, additional, Nambela, Estelle, additional, Townshend, Paula, additional, Ford, Chris, additional, Holder, Sophie, additional, Palmer, Caroline, additional, Featherstone, James, additional, Nasseri, Mariam, additional, Sadeghian, Joy, additional, Williams, Bronwen, additional, Thomas, Carol, additional, Rolls, Sally-Ann, additional, Hynes, Abigail, additional, Duggan, Claire, additional, Jones, Sarah, additional, Crossey, Mary, additional, Stansfield, Glynis, additional, MacNicol, Carolyn, additional, Wilkins, Joy, additional, Wilhelmsen, Elva, additional, Raymode, Parizade, additional, Lee, Hye-Jeong, additional, Durant, Emma, additional, Bishop, Rebecca, additional, Ncube, Noma, additional, Tripoli, Sherill, additional, Casey, Rebecca, additional, Cowley, Caroline, additional, Miller, Richard, additional, Houghton, Kathryn, additional, Ducker, Samantha, additional, Wright, Fiona, additional, Bird, Bridget, additional, Baxter, Gwen, additional, Keggans, Janie, additional, Hughes, Maggie, additional, Grieve, Emma, additional, Young, Karin, additional, Williams, D., additional, Ocker, Kate, additional, Hines, Frances, additional, Martin, Kirsty, additional, Innes, Caron, additional, Valliani, Talal, additional, Fairlamb, Helen, additional, Thornthwaite, Sarah, additional, Eastick, Anne, additional, Tanqueray, Elizabeth, additional, Morrison, Jennifer, additional, Holbrook, Becky, additional, Browning, Julie, additional, Walker, Kirsten, additional, Congreave, Susan, additional, Verheyden, Juliette, additional, Slininger, Susan, additional, Stafford, Lizzie, additional, O’Donnell, Denise, additional, Ainsworth, Mark, additional, Lord, Susan, additional, Kent, Linda, additional, March, Linda, additional, Dickson, Christine, additional, Simpson, Diane, additional, Longhurst, Beverley, additional, Hayes, Maria, additional, Shpuza, Ervin, additional, White, Nikki, additional, Besley, Sarah, additional, Pearson, Sallyanne, additional, Wright, Alice, additional, Jones, Linda, additional, Gunter, Emma, additional, Dewhurst, Hannah, additional, Fouracres, Anna, additional, Farrington, Liz, additional, Graves, Lyn, additional, Marriott, Suzie, additional, Leoni, Marina, additional, Tyrer, David, additional, Martin, Kate, additional, Dali-kemmery, Lola, additional, Lambourne, Victoria, additional, Green, Marie, additional, Sirdefield, Dawn, additional, Amor, Kelly, additional, Colley, Julie, additional, Shinder, Bal, additional, Jones, Jayne, additional, Mills, Marisa, additional, Carnahan, Mandy, additional, Taylor, Natalie, additional, Boulton, Kerenza, additional, Tregonning, Julie, additional, Brown, Carly, additional, Clifford, Gayle, additional, Archer, Emily, additional, Hamilton, Maria, additional, Curtis, Janette, additional, Shewan, Tracey, additional, Walsh, Sue, additional, Warner, Karen, additional, Netherton, Kimberley, additional, Mupudzi, Mcdonald, additional, Gunson, Bridget, additional, Gitahi, Jane, additional, Gocher, Denise, additional, Batham, Sally, additional, Pateman, Hilary, additional, Desmennu, Senayon, additional, Conder, Jill, additional, Clement, Darren, additional, Gallagher, Susan, additional, Orpe, Jacky, additional, Chan, PuiChing, additional, Currie, Lynn, additional, O’Donohoe, Lynn, additional, Oblak, Metod, additional, Morgan, Lisa, additional, Quinn, Marie, additional, Amey, Isobel, additional, Baird, Yolanda, additional, Cotterill, Donna, additional, Cumlat, Lourdes, additional, Winter, Louise, additional, Greer, Sandra, additional, Spurdle, Katie, additional, Allison, Joanna, additional, Dyer, Simon, additional, Sweeting, Helen, additional, Kordula, Jean, additional, Aiba, Yoshihiro, additional, Nakamura, Hitomi, additional, Abiru, Seigo, additional, Nagaoka, Shinya, additional, Komori, Atsumasa, additional, Yatsuhashi, Hiroshi, additional, Ishibashi, Hiromi, additional, Ito, Masahiro, additional, Kawai, Yosuke, additional, Kohn, Seik-Soon, additional, Gervais, Olivier, additional, Migita, Kiyoshi, additional, Katsushima, Shinji, additional, Naganuma, Atsushi, additional, Sugi, Kazuhiro, additional, Komatsu, Tatsuji, additional, Mannami, Tomohiko, additional, Matsushita, Kouki, additional, Yoshizawa, Kaname, additional, Makita, Fujio, additional, Nikami, Toshiki, additional, Nishimura, Hideo, additional, Kouno, Hiroshi, additional, Kouno, Hirotaka, additional, Ota, Hajime, additional, Komura, Takuya, additional, Nakamura, Yoko, additional, Shimada, Masaaki, additional, Hirashima, Noboru, additional, Komeda, Toshiki, additional, Ario, Keisuke, additional, Nakamuta, Makoto, additional, Yamashita, Tsutomu, additional, Furuta, Kiyoshi, additional, Kikuchi, Masahiro, additional, Naeshiro, Noriaki, additional, Takahashi, Hironao, additional, Mano, Yutaka, additional, Tsunematsu, Seiji, additional, Yabuuchi, Iwao, additional, Shimada, Yusuke, additional, Yamauchi, Kazuhiko, additional, Sugimoto, Rie, additional, Sakai, Hironori, additional, Mita, Eiji, additional, Koda, Masaharu, additional, Tsuruta, Satoru, additional, Kamitsukasa, Hiroshi, additional, Sato, Takeaki, additional, Masaki, Naohiko, additional, Kobata, Tatsuro, additional, Fukushima, Nobuyoshi, additional, Higuchi, Nobito, additional, Ohara, Yukio, additional, Muro, Toyokichi, additional, Takesaki, Eiichi, additional, Takaki, Hitoshi, additional, Yamamoto, Tetsuo, additional, Kato, Michio, additional, Nagaoki, Yuko, additional, Hayashi, Shigeki, additional, Ishida, Jinya, additional, Watanabe, Yukio, additional, Kobayashi, Masakazu, additional, Koga, Michiaki, additional, Saoshiro, Takeo, additional, Yagura, Michiyasu, additional, Hirata, Keisuke, additional, Takikawa, Hajime, additional, Ohira, Hiromasa, additional, Zeniya, Mikio, additional, Abe, Masanori, additional, Onji, Morikazu, additional, Kaneko, Shuichi, additional, Honda, Masao, additional, Arai, Kuniaki, additional, Arinaga-Hino, Teruko, additional, Hashimoto, Etsuko, additional, Taniai, Makiko, additional, Umemura, Takeji, additional, Joshita, Satoru, additional, Nakao, Kazuhiko, additional, Ichikawa, Tatsuki, additional, Shibata, Hidetaka, additional, Yamagiwa, Satoshi, additional, Seike, Masataka, additional, Honda, Koichi, additional, Sakisaka, Shotaro, additional, Takeyama, Yasuaki, additional, Harada, Masaru, additional, Senju, Michio, additional, Yokosuka, Osamu, additional, Kanda, Tatsuo, additional, Ueno, Yoshiyuki, additional, Kikuchi, Kentaro, additional, Ebinuma, Hirotoshi, additional, Himoto, Takashi, additional, Yasunami, Michio, additional, Murata, Kazumoto, additional, Mizokami, Masashi, additional, Shimoda, Shinji, additional, Miyake, Yasuhiro, additional, Takaki, Akinobu, additional, Yamamoto, Kazuhide, additional, Hirano, Katsuji, additional, Ichida, Takafumi, additional, Ido, Akio, additional, Tsubouchi, Hirohito, additional, Chayama, Kazuaki, additional, Harada, Kenichi, additional, Nakanuma, Yasuni, additional, Maehara, Yoshihiko, additional, Taketomi, Akinobu, additional, Shirabe, Ken, additional, Soejima, Yuji, additional, Mori, Akira, additional, Yagi, Shintaro, additional, Uemoto, Shinji, additional, Tanaka, Tomohiro, additional, Yamashiki, Noriyo, additional, Tamura, Sumito, additional, Sugawara, Yasuhiro, additional, and Kokudo, Norihiro, additional

Published
2021
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20. Association of soluble T cell immunoglobulin domain and mucin-3 (sTIM-3) and mac-2 binding protein glycosylation isomer (M2BPGi) in patients with autoimmune hepatitis

Author

Migita, Kiyoshi, primary, Nakamura, Minoru, additional, Aiba, Yoshihiro, additional, Kozuru, Hideko, additional, Abiru, Seigo, additional, Komori, Atsumasa, additional, Fujita, Yuya, additional, Temmoku, Junpei, additional, Asano, Tomoyuki, additional, Sato, Shuzo, additional, Furuya, Makiko, additional, Naganuma, Atsushi, additional, Yoshizawa, Kaname, additional, Shimada, Masaaki, additional, Ario, Keisuke, additional, Mannami, Tomohiko, additional, Kohno, Hiroshi, additional, Kaneyoshi, Toshihiko, additional, Komura, Takuya, additional, Ohira, Hiromasa, additional, and Yatsuhashi, Hiroshi, additional

Published
2020
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21. Continuous Warfarin Administration Versus Heparin Bridging Therapy in Post Colorectal Polypectomy Hemorrhage: A Study Protocol for a Multicenter Randomized Controlled Trial (WHICH Study)

Author

Nagami, Yasuaki, primary, Sakai, Taishi, additional, Yamamura, Masafumi, additional, Nakatani, Masami, additional, Katsuno, Takayuki, additional, Suekane, Takehisa, additional, Uno, Hironori, additional, Minamino, Hiroaki, additional, Okuyama, Masatsugu, additional, Okamoto, Junichi, additional, Kumamoto, Mitsutaka, additional, Noguchi, Atsushi, additional, Yamamori, Kazuki, additional, Takaishi, Osamu, additional, Ochi, Masahiro, additional, Miyazaki, Takako, additional, Tsuji, Shigetsugu, additional, Ikehara, Hisatomo, additional, Kawaguchi, Koichiro, additional, Hayashi, Tomoyuki, additional, Mannami, Tomohiko, additional, Kakimoto, Kazuki, additional, Naito, Yoshihide, additional, Hashimoto, Satoru, additional, Li, Zhaoliang, additional, Komeda, Yoriaki, additional, Kishino, Takaaki, additional, Yamamoto, Yoshinobu, additional, Iguchi, Mikitaka, additional, Akamatsu, Takuji, additional, Horii, Toshiki, additional, Miura, Ko, additional, Yamashina, Takeshi, additional, Sugihara, Yuusaku, additional, Watanabe, Noboru, additional, Kiyotoki, Shu, additional, Fujii, Ryoji, additional, Murata, Masaki, additional, Ono, Satoshi, additional, Narasaka, Toshiaki, additional, Kitamura, Shinji, additional, Kono, Mitsuhiro, additional, Kato, Motohiko, additional, Kawaratani, Hideto, additional, Tanaka, Kyosuke, additional, Yaoita, Takao, additional, Yamaguchi, Shinjiro, additional, Abe, Keiichiro, additional, Kawamura, Takuji, additional, Kinoshita, Yosuke, additional, Imai, Kenichiro, additional, Fujinami, Haruka, additional, Yada, Tomoyuki, additional, Miyamoto, Hayato, additional, Yoshida, Hisako, additional, and Fujiwara, Yasuhiro, additional

Published
2020
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23. Complications after Radiofrequency Ablation for Hepatocellular Carcinoma: A Multicenter Study Involving 9,411 Japanese Patients

Author

Maeda, Masaki, primary, Saeki, Issei, additional, Sakaida, Isao, additional, Aikata, Hiroshi, additional, Araki, Yasuyuki, additional, Ogawa, Chikara, additional, Kariyama, Kazuya, additional, Nouso, Kazuhiro, additional, Kitamoto, Mikiya, additional, Kobashi, Haruhiko, additional, Sato, Shuichi, additional, Shibata, Hiroshi, additional, Joko, Kouji, additional, Takaki, Shintaro, additional, Takabatake, Hiroyuki, additional, Tsutsui, Akemi, additional, Takaguchi, Koichi, additional, Tomonari, Tetsu, additional, Nakamura, Shinichiro, additional, Nagahara, Takakazu, additional, Hiraoka, Atsushi, additional, Matono, Tomomitsu, additional, Koda, Masahiko, additional, Mandai, Mari, additional, Mannami, Tomohiko, additional, Mitsuda, Akeri, additional, Moriya, Takashi, additional, Yabushita, Kazuhisa, additional, Tani, Joji, additional, Yagi, Takahito, additional, and Yamasaki, Takahiro, additional

Published
2019
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31. Integrated GWAS and mRNA Microarray Analysis Identified IFNG and CD40L as the Central Upstream Regulators in Primary Biliary Cholangitis.

Author

Ueno, Kazuko, Aiba, Yoshihiro, Hitomi, Yuki, Shimoda, Shinji, Nakamura, Hitomi, Gervais, Olivier, Kawai, Yosuke, Kawashima, Minae, Nishida, Nao, Kohn, Seik‐Soon, Kojima, Kaname, Katsushima, Shinji, Naganuma, Atsushi, Sugi, Kazuhiro, Komatsu, Tatsuji, Mannami, Tomohiko, Matsushita, Kouki, Yoshizawa, Kaname, Makita, Fujio, and Nikami, Toshiki

Subjects
MESSENGER RNA, CHOLANGITIS
Abstract

Genome‐wide association studies (GWASs) in European and East Asian populations have identified more than 40 disease‐susceptibility genes in primary biliary cholangitis (PBC). The aim of this study is to computationally identify disease pathways, upstream regulators, and therapeutic targets in PBC through integrated GWAS and messenger RNA (mRNA) microarray analysis. Disease pathways and upstream regulators were analyzed with ingenuity pathway analysis in data set 1 for GWASs (1,920 patients with PBC and 1,770 controls), which included 261 annotated genes derived from 6,760 single‐nucleotide polymorphisms (P < 0.00001), and data set 2 for mRNA microarray analysis of liver biopsy specimens (36 patients with PBC and 5 normal controls), which included 1,574 genes with fold change >2 versus controls (P < 0.05). Hierarchical cluster analysis and categorization of cell type–specific genes were performed for data set 2. There were 27 genes, 10 pathways, and 149 upstream regulators that overlapped between data sets 1 and 2. All 10 pathways were immune‐related. The most significant common upstream regulators associated with PBC disease susceptibility identified were interferon‐gamma (IFNG) and CD40 ligand (CD40L). Hierarchical cluster analysis of data set 2 revealed two distinct groups of patients with PBC by disease activity. The most significant upstream regulators associated with disease activity were IFNG and CD40L. Several molecules expressed in B cells, T cells, Kupffer cells, and natural killer–like cells were identified as potential therapeutic targets in PBC with reference to a recently reported list of cell type–specific gene expression in the liver. Conclusion: Our integrated analysis using GWAS and mRNA microarray data sets predicted that IFNG and CD40L are the central upstream regulators in both disease susceptibility and activity of PBC and identified potential downstream therapeutic targets. [ABSTRACT FROM AUTHOR]

Published
2020
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32. Evaluation of an e-learning system for diagnosis of gastric lesions using magnifying narrow-band imaging: a multicenter randomized controlled study

Author

Nakanishi, Hiroyoshi, additional, Doyama, Hisashi, additional, Ishikawa, Hideki, additional, Uedo, Noriya, additional, Gotoda, Takuji, additional, Kato, Mototsugu, additional, Nagao, Shigeaki, additional, Nagami, Yasuaki, additional, Aoyagi, Hiroyuki, additional, Imagawa, Atsushi, additional, Kodaira, Junichi, additional, Mitsui, Shinya, additional, Kobayashi, Nozomu, additional, Muto, Manabu, additional, Takatori, Hajime, additional, Abe, Takashi, additional, Tsujii, Masahiko, additional, Watari, Jiro, additional, Ishiyama, Shuhei, additional, Oda, Ichiro, additional, Ono, Hiroyuki, additional, Kaneko, Kazuhiro, additional, Yokoi, Chizu, additional, Ueo, Tetsuya, additional, Uchita, Kunihisa, additional, Matsumoto, Kenshi, additional, Kanesaka, Takashi, additional, Morita, Yoshinori, additional, Katsuki, Shinichi, additional, Nishikawa, Jun, additional, Inamura, Katsuhisa, additional, Kinjo, Tetsu, additional, Yamamoto, Katsumi, additional, Yoshimura, Daisuke, additional, Araki, Hiroshi, additional, Kashida, Hiroshi, additional, Hosokawa, Ayumu, additional, Mori, Hirohito, additional, Yamashita, Haruhiro, additional, Motohashi, Osamu, additional, Kobayashi, Kazuhiko, additional, Hirayama, Michiaki, additional, Kobayashi, Hiroyuki, additional, Endo, Masaki, additional, Yamano, Hiroo, additional, Murakami, Kazunari, additional, Koike, Tomoyuki, additional, Hirasawa, Kingo, additional, Miyaoka, Youichi, additional, Hamamoto, Hidetaka, additional, Hikichi, Takuto, additional, Hanabata, Norihiro, additional, Shimoda, Ryo, additional, Hori, Shinichiro, additional, Sato, Tadashi, additional, Kodashima, Shinya, additional, Okada, Hiroyuki, additional, Mannami, Tomohiko, additional, Yamamoto, Shojiro, additional, Niwa, Yasumasa, additional, Yashima, Kazuo, additional, Tanabe, Satoshi, additional, Satoh, Hiro, additional, Sasaki, Fumisato, additional, Yamazato, Tetsuro, additional, Ikeda, Yoshiou, additional, Nishisaki, Hogara, additional, Nakagawa, Masahiro, additional, Matsuda, Akio, additional, Tamura, Fumio, additional, Nishiyama, Hitoshi, additional, Arita, Keiko, additional, Kawasaki, Keisuke, additional, Hoppo, Kazushige, additional, Oka, Masashi, additional, Ishihara, Shinichi, additional, Mukasa, Michita, additional, Minamino, Hiroaki, additional, and Yao, Kenshi, additional

Published
2017
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33. 116 Prospective, Multicenter Study for Evaluation of the Clinical Efficacy and Safety of Pillcam Patency Capsule in 1,096 Cases With Suspected Small Bowel Stenosis

Author

Nakamura, Masanao, primary, Watanabe, Kenji, additional, Ohmiya, Naoki, additional, Hirai, Fumihito, additional, Omori, Teppei, additional, Tokuhara, Daisuke, additional, Nakaji, Konosuke, additional, Nouda, Sadaharu, additional, Washio, Ema, additional, SAMESHIMA, Yukinori, additional, Mannami, Tomohiko, additional, Maeda, Kohei, additional, Ninomiya, Kazeo, additional, Wakamatsu, Takahiro, additional, Araki, Akihiro, additional, Ishii, Manabu, additional, Higaki, Shingo, additional, Abe, Takashi, additional, Handa, Osamu, additional, Kawano, Seiji, additional, Iwamoto, Maho, additional, Kato, Shingo, additional, Kagaya, Takashi, additional, Goto, Hidemi, additional, and Matsui, Toshiyuki, additional

Published
2017
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34. Su1154 A Nationwide Multicenter Study on Adverse Events Associated With a Patency Capsule: Additional Survey for the Japanese Association for Capsule Endoscopy-Oriented Appropriate Use Survey for Patency Capsule (J-Pop) Study

Author

Omori, Teppei, primary, Watanabe, Kenji, additional, Ohmiya, Naoki, additional, Hirai, Fumihito, additional, Nakamura, Masanao, additional, Kagaya, Takashi, additional, Oka, Shiro, additional, Ozeki, Keiji, additional, Kawano, Seiji, additional, Ninomiya, Kazeo, additional, Nakaji, Konosuke, additional, Iimuro, Masaki, additional, Handa, Osamu, additional, Tokuhara, Daisuke, additional, Sagawa, Tamotsu, additional, Wakamatsu, Takahiro, additional, Kato, Shingo, additional, Araki, Akihiro, additional, Koike, Yuji, additional, Hashimoto, Shinichi, additional, Mannami, Tomohiko, additional, Higaki, Shingo, additional, Hayashida, Mari, additional, SAMESHIMA, Yukinori, additional, Hasegawa, Daisuke, additional, Tokushige, Katsutoshi, additional, and Matsui, Toshiyuki, additional

Published
2017
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35. Complications after Radiofrequency Ablation for Hepatocellular Carcinoma: A Multicenter Study Involving 9,411 Japanese Patients

Author

Maeda, Masaki, Saeki, Issei, Sakaida, Isao, Aikata, Hiroshi, Araki, Yasuyuki, Ogawa, Chikara, Kariyama, Kazuya, Nouso, Kazuhiro, Kitamoto, Mikiya, Kobashi, Haruhiko, Sato, Shuichi, Shibata, Hiroshi, Joko, Kouji, Takaki, Shintaro, Takabatake, Hiroyuki, Tsutsui, Akemi, Takaguchi, Koichi, Tomonari, Tetsu, Nakamura, Shinichiro, Nagahara, Takakazu, Hiraoka, Atsushi, Matono, Tomomitsu, Koda, Masahiko, Mandai, Mari, Mannami, Tomohiko, Mitsuda, Akeri, Moriya, Takashi, Yabushita, Kazuhisa, Tani, Joji, Yagi, Takahito, and Yamasaki, Takahiro

Abstract

Introduction:Radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) is considered a safe and minimally invasive procedure. We previously reported that the mortality and complication rates for RFA were 0.038% (5/13,283 patients) and 3.54% (579 complications/16,346 procedures), respectively, from 1999 to 2010 (previous period). In this study, we investigated the clinical criteria for RFA and the mortality and complication rates from 2011 to 2015 (recent period). Methods:Data were collected from 25 centers by using a questionnaire developed by the Chugoku-Shikoku Society for Local Ablation Therapy of HCC. The criteria for RFA, RFA modification, use of image-guidance modalities, mortality, and complications during the previous and recent periods were compared. Results:We evaluated 11,298 procedures for 9,411 patients, including those that involved new devices (bipolar RFA and internally adjustable electrode system). The criterion of hepatic function for RFA increased from a Child-Pugh score ≤8 during the previous period to ≤9 during the recent period. The criteria regarding the tumor location and other risk factors have been expanded recently because of the increased use of several modifications of the RFA procedure and image-guidance modalities. The mortality rate was 0.064% (6/9,411 patients), and the complication rate was 2.92% (330 complications/11,298 procedures). There was no difference in mortality rates between the 2 periods (p= 0.38), but the complication rates was significantly lower during the recent period (p= 0.038). Discussion and Conclusions:Our findings confirmed that RFA, including the use of new devices, is a low-risk procedure for HCC, despite the expansion of the criteria for RFA during the recent period.

Published
2020
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37. Gastric adenocarcinoma of fundic gland type with two closely located lesions endoscopically resected en masse.

Author

Mannami, Tomohiko, Tanaka, Takehiro, and Fujiwara, Nobukiyo

Subjects
*GASTRIC fundus surgery, *ADENOCARCINOMA, *STOMACH tumors, *GASTRIC fundus, *GASTRIC mucosa
Abstract

The lesions had diffuse positivity for MUC6, focal positivity for H SP + sp /K SP + sp -ATPase, and negativity for MUC2, MUC5AC, CD10, and pepsinogen I. Both lesions were diagnosed as adenocarcinomas of the fundic gland type. A biopsy from the anterior-sided lesion was diagnosed as gastric adenocarcinoma of the fundic gland type. [Extracted from the article]

Published
2022
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39. Correlation Between Histological Evaluation and PCR-based Clonality Analysis of Gastric MALT Lymphomas Treated by Eradication of Helicobacter pylori.

Author

Sakugawa, Sumie Takase, primary, Yoshino, Tadashi, additional, Mannami, Tomohiko, additional, Munemasa, Mitsuru, additional, Ichimura, Koichi, additional, Okada, Hiroyuki, additional, Mizuno, Motowo, additional, Tanimoto, Mitsune, additional, Harada, Mine, additional, and Akagi, Tadaatsu, additional

Published
2002
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43. Gastrointestinal hemorrhage caused by the direct invasion of a hepatocellular carcinoma successfully treated with polyglycolic acid sheet shielding.

Author

Tomohiko Mannami, Nobukiyo Fujiwara, Genyo Ikeda, Takahito Mishima, Taiga Kuroi, Takayuki Muraoka, Yasuyuki Ohtawa, Mannami, Tomohiko, Fujiwara, Nobukiyo, Ikeda, Genyo, Mishima, Takahito, Kuroi, Taiga, Muraoka, Takayuki, and Ohtawa, Yasuyuki

Subjects
LIVER cancer, CIRRHOSIS of the liver
Abstract

The article presents a case study of a 76-year-old man with a history of alcohol liver cirrhosis who have been previously diagnosed with hepatocellular carcinoma.

Published
2019
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45. Gastrointestinal hemorrhage caused by the direct invasion of a hepatocellular carcinoma successfully treated with polyglycolic acid sheet shielding.

Author

Mannami T, Fujiwara N, Ikeda G, Mishima T, Kuroi T, Muraoka T, and Ohtawa Y

Subjects
Aged, Fatal Outcome, Gastrointestinal Hemorrhage diagnostic imaging, Humans, Male, Tomography, X-Ray Computed, Carcinoma, Hepatocellular complications, Endoscopy, Digestive System, Fibrin Tissue Adhesive therapeutic use, Gastrointestinal Hemorrhage drug therapy, Gastrointestinal Hemorrhage etiology, Liver Neoplasms complications, Polyglycolic Acid therapeutic use
Abstract

Competing Interests: None, (© Georg Thieme Verlag KG Stuttgart · New York.)

Published
2019
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46. [HER2-Positive Advanced Gastric Cancer with Disseminated Intravascular Coagulation and Diffuse Bone Marrow Carcinomatosis Successfully Treated with S-1/Trastuzumab Chemotherapy--A Case Report].

Author

Senoo S, Mannami T, Tamura T, Fujiwara N, Ikeda G, Komoda M, Ohtawa Y, Fujimoto Y, Sato N, Kambara T, Waku T, Kenmotsu M, Kurimoto E, Okada T, Harita S, and Sonobe H

Subjects
Aged, Anticoagulants therapeutic use, Biopsy, Bone Marrow Neoplasms secondary, Bone Neoplasms secondary, Carcinoma, Signet Ring Cell chemistry, Disseminated Intravascular Coagulation drug therapy, Drug Combinations, Fatal Outcome, Female, Humans, Oxonic Acid administration & dosage, Receptor, ErbB-2 analysis, Stomach Neoplasms pathology, Tegafur administration & dosage, Trastuzumab administration & dosage, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Bone Marrow Neoplasms drug therapy, Bone Neoplasms drug therapy, Carcinoma, Signet Ring Cell drug therapy, Disseminated Intravascular Coagulation etiology, Stomach Neoplasms drug therapy
Abstract

Trastuzumab, a humanized monoclonal antibody against human epidermal growth factor receptor 2 (HER2), has been proven to result in a survival benefit for the treatment of patients with HER2-positive advanced gastric cancer (AGC). However, data are lacking for the treatment of those with disseminated intravascular coagulation (DIC) and diffuse bone marrow carcinomatosis. A 77-year-old woman presented with back pain and fatigue since 2 months. Esophagogastroduodenoscopy showed a scirrhous lesion in the gastric corpus, which was biopsied and identified as signet-ring cell carcinoma with HER2 overexpression on immunohistochemistry. Laboratory testing, bone scintigraphy, and bone marrow biopsy were conducted, and she was diagnosed with HER2-positive AGC with DIC and diffuse bone marrow carcinomatosis. She underwent chemotherapy with the following regimen: oral administration of 80 mg/m2 S-1 for 2 weeks and 6 mg/kg trastuzumab infusion on day 6 every 3 weeks, which significantly improved the DIC. She was discharged from the hospital 73 days after admission and survived for 438 days after diagnosis. To the best of our knowledge, this is the first case report in which HER2-positive AGC complicated by DIC with diffuse bone marrow carcinomatosis was successfully treated with combined chemotherapy consisting of S-1 plus trastuzumab.

Published
2015

47. [A case of advanced gastric cancer with multiple bone metastases and disseminated intravascular coagulation successfully treated by combination chemotherapy of S-1 plus docetaxel].

Author

Ninomiya K, Mannami T, Seno S, Suzuki Y, Tamura T, Kimura K, Kubo T, Masunari T, Okada T, Kiguchi T, Sezaki N, Harita S, Nakata Y, and Sonobe H

Subjects
Aged, Bone Neoplasms secondary, Docetaxel, Drug Combinations, Fatal Outcome, Female, Humans, Oxonic Acid administration & dosage, Stomach Neoplasms complications, Stomach Neoplasms pathology, Taxoids administration & dosage, Tegafur administration & dosage, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Bone Neoplasms drug therapy, Disseminated Intravascular Coagulation etiology, Stomach Neoplasms drug therapy
Abstract

Advanced gastric cancer (AGC) accompanied by disseminated intravascular coagulation(DIC)has a poor prognosis, and has no established therapy. Here, we report a case of a 69-year-old woman referred to our hospital due to severe anemia and thrombocytopenia. Esophagogastroduodenoscopy demonstrated an AGC in the cardiac part of the stomach, which was histologically diagnosed as poorly-differentiated adenocarcinoma. Bone scintigraphy showed multiple metastases to the bone marrow. Her diagnosis was DIC resulting from AGC, with multiple bone metastases. She underwent chemotherapy with the following regimen: 60mg/m2 docetaxel(DOC)infusion on day 1 and daily oral administration of 100 mg/m2 S-1 for two weeks every three weeks. DIC subsided rapidly after initiation of the therapy and resolved in 12 days. She was discharged from the hospital 56 days after admission and survived 303 days. To our knowledge, this is the first case of AGC reported in the Japanese and English literature to obtain long-term survival in this setting. Combined chemotherapy of S-1 plus DOC may play an important role in the treatment of AGC developing DIC.

Published
2012

48. Expression of thyroglobulin on follicular dendritic cells of thyroid mucosa-associated lymphoid tissue (MALT) lymphoma.

Author

Munemasa M, Yoshino T, Kobayashi K, Miyake T, Takase-Sakugawa S, Mannami T, Shinagawa K, Tanimoto M, and Akagi T

Subjects
Adult, Aged, Animals, Autoantigens immunology, Dendritic Cells, Follicular cytology, Female, Gene Rearrangement, Humans, Immunoglobulin Heavy Chains genetics, Immunohistochemistry, Lymphoma, B-Cell, Marginal Zone genetics, Lymphoma, B-Cell, Marginal Zone pathology, Male, Mice, Middle Aged, Rabbits, Receptors, Complement 3b metabolism, Young Adult, Dendritic Cells, Follicular immunology, Lymphoma, B-Cell, Marginal Zone immunology, Thyroglobulin metabolism
Abstract

Reportedly, thyroid mucosa-associated lymphoid tissue (MALT) lymphoma is closely associated with Hashimoto's thyroiditis. However, it remains unknown which antigen is closely associated with thyroid MALT lymphoma. We examined whether B cell response to thyroglobulin (Tg), which is a common thyroid-specific autoantigen, is related etiologically to the pathogenesis of thyroid MALT lymphoma. Expression of human Tg antigens and Cluster of differentiation (CD) 35 was examined immunohistochemically in 15 cases of thyroid MALT lymphoma using paraffin-embedded, formalin-fixed tissue specimens. In all cases of thyroid MALT lymphoma, human Tg was detected immunohistochemically in the follicular epithelial cells and follicular dendritic cells (FDCs). These FDCs were positive by double immunostaining for anti-human Tg rabbit polyclonal antibody (Ab) and for CD35. Results showed that the Tg, a thyroid autoantigen, had immunostained the germinal center of the thyroid MALT lymphoma. The Tg was present in the FDCs, as revealed by the staining pattern of the germinal center;this fact was confirmed by double immunostaining of anti-human Tg mouse monoclonal Ab and anti-CD35 mouse monoclonal Ab. The results of our study suggest that Tg is an autoantigen that is recognized by thyroid MALT lymphoma cells.

Published
2009
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49. [Ciliated hepatic foregut cyst: report of a case and a summary of the 24 cases reported in Japan].

Author

Mannami T, Ohfuji Y, Fujiwara K, Enomura K, Ohta T, Kunisue H, Nomura S, Eguchi K, Oda W, Yamadori I, and Yamashita H

Subjects
Cysts pathology, Humans, Liver Diseases pathology, Male, Middle Aged, Cysts congenital, Liver Diseases congenital
Abstract

We report a 52-year-old patient with a small hepatic mass which was ultrasonographically anechoic with scattered high echoic spots, and appearing slightly hyperattenuating relative to the surrounding parenchyma on unenhanced CT scans. Laparotomy revealed that the lesion was a unilocular cyst containing a mucinous fluid. The histologic diagnosis was ciliated hepatic foregut cyst (CHFC). The CHFC is a rare congenital cystic tumor which derives from the embryologic foregut. Up to 2006, only 24 cases, including our case, had been reported in Japan. The patients were 13 men and 11 women, aged between 41 years and 79 years. All of the lesions were solitary and unilocular. In 22 cases, the CHFC was located in the medial segment of the left lobe, mostly just beneath the hepatic surface. In all 24 Japanese cases, the cystic wall was benign histologically. However, reports of 3 malignant cases overseas indicates we should treat this disease cautiously.

Published
2008

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