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Introduction: Fractures are usually associated with functional impairment and dependence; also bears psychological effect as the quality of life decreases. Many studies have shown the presence of depression associated with the fracture and hence the study was done to know the same in our institution. Methods: Inclusion criteria: Adults aged more than 35 years of both sexes who had sustained fractures of long bones, hip and vertebral fractures who were admitted as inpatients earlier, and requiring prolonged rehabilitation. Exclusion criteria: Severely medically ill patients. The mood state was evaluated in patients with fractures after taking consent with Beck’s Depression inventory. Follow up of inpatient with fracture were done after their discharge. Results: This study shows that among patients with fractures, higher prevalence of moderate and severe depression is in females. Post-menopausal women are most severely affected. Conclusion: Postmenopausal females suffer more from depression associated with fractures than males.