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1. Measurement of Energy Resolution with the NEXT-White Silicon Photomultipliers

Author

Contreras, T., Palmeiro, B., Almazán, H., Para, A., Martínez-Lema, G., Guenette, R., Adams, C., Álvarez, V., Aparicio, B., Aranburu, A. I., Arazi, L., Arnquist, I. J., Auria-Luna, F., Ayet, S., Azevedo, C. D. R., Bailey, K., Ballester, F., del Barrio-Torregrosa, M., Bayo, A., Benlloch-Rodríguez, J. M., Borges, F. I. G. M., Brodolin, A., Byrnes, N., Cárcel, S., Castillo, A., Cebrián, S., Church, E., Cid, L., Conde, C. A. N., Cossío, F. P., Dey, E., Díaz, G., Dickel, T., Echevarria, C., Elorza, M., Escada, J., Esteve, R., Felkai, R., Fernandes, L. M. P., Ferrario, P., Ferreira, A. L., Foss, F. W., Freixa, Z., García-Barrena, J., Gómez-Cadenas, J. J., González, R., Grocott, J. W. R., Hauptman, J., Henriques, C. A. O., Morata, J. A. Hernando, Herrero-Gómez, P., Herrero, V., Carrete, C. Hervés, Ifergan, Y., Jones, B. J. P., Kellerer, F., Larizgoitia, L., Larumbe, A., Lebrun, P., Lopez, F., López-March, N., Madigan, R., Mano, R. D. P., Marques, A. P., Martín-Albo, J., Martínez-Vara, M., Miller, R. L., Mistry, K., Molina-Canteras, J., Monrabal, F., Monteiro, C. M. B., Mora, F. J., Navarro, K. E., Novella, P., Nuñez, A., Nygren, D. R., Oblak, E., Palacio, J., Parmaksiz, I., Pazos, A., Pelegrin, J., Maneiro, M. Pérez, Querol, M., Redwine, A. B., Renner, J., Rivilla, I., Rogero, C., Rogers, L., Romeo, B., Romo-Luque, C., Santos, F. P., Santos, J. M. F. dos, Seemann, M., Shomroni, I., Silva, P. A. O. C., Simón, A., Soleti, S. R., Sorel, M., Soto-Oton, J., Teixeira, J. M. R., Teruel-Pardo, S., Toledo, J. F., Tonnelé, C., Torrent, J., Trettin, A., Usón, A., Valle, P. R. G., Veloso, J. F. C. A., Waiton, J., and Yubero-Navarro, A.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The NEXT-White detector, a high-pressure gaseous xenon time projection chamber, demonstrated the excellence of this technology for future neutrinoless double beta decay searches using photomultiplier tubes (PMTs) to measure energy and silicon photomultipliers (SiPMs) to extract topology information. This analysis uses $^{83m}\text{Kr}$ data from the NEXT-White detector to measure and understand the energy resolution that can be obtained with the SiPMs, rather than with PMTs. The energy resolution obtained of (10.9 $\pm$ 0.6) $\%$, full-width half-maximum, is slightly larger than predicted based on the photon statistics resulting from very low light detection coverage of the SiPM plane in the NEXT-White detector. The difference in the predicted and measured resolution is attributed to poor corrections, which are expected to be improved with larger statistics. Furthermore, the noise of the SiPMs is shown to not be a dominant factor in the energy resolution and may be negligible when noise subtraction is applied appropriately, for high-energy events or larger SiPM coverage detectors. These results, which are extrapolated to estimate the response of large coverage SiPM planes, are promising for the development of future, SiPM-only, readout planes that can offer imaging and achieve similar energy resolution to that previously demonstrated with PMTs.

Published
2024

2. Fluorescence Imaging of Individual Ions and Molecules in Pressurized Noble Gases for Barium Tagging in $^{136}$Xe

Author

NEXT Collaboration, Byrnes, N., Dey, E., Foss, F. W., Jones, B. J. P., Madigan, R., McDonald, A., Miller, R. L., Navarro, K. E., Norman, L. R., Nygren, D. R., Adams, C., Almazán, H., Álvarez, V., Aparicio, B., Aranburu, A. I., Arazi, L., Arnquist, I. J., Auria-Luna, F., Ayet, S., Azevedo, C. D. R., Barcelon, J. E., Bailey, K., Ballester, F., del Barrio-Torregrosa, M., Bayo, A., Benlloch-Rodríguez, J. M., Borges, F. I. G. M., Brodolin, A., Cárcel, S., Castillo, A., Cebrián, S., Church, E., Cid, L., Conde, C. A. N., Contreras, T., Cossío, F. P., Díaz, G., Dickel, T., Echevarria, C., Elorza, M., Escada, J., Esteve, R., Felkai, R., Fernandes, L. M. P., Ferrario, P., Ferreira, A. L., Freixa, Z., García-Barrena, J., Gómez-Cadenas, J. J., González, R., Grocott, J. W. R., Guenette, R., Hauptman, J., Henriques, C. A. O., Morata, J. A. Hernando, Herrero-Gómez, P., Herrero, V., Carrete, C. Hervés, Ho, P., Ifergan, Y., Kellerer, F., Larizgoitia, L., Larumbe, A., Lebrun, P., Lopez, F., López-March, N., Mano, R. D. P., Marques, A. P., Martín-Albo, J., Martínez-Lema, G., Martínez-Vara, M., Mistry, K., Molina-Canteras, J., Monrabal, F., Monteiro, C. M. B., Mora, F. J., Novella, P., Nuñez, A., Oblak, E., Palacio, J., Palmeiro, B., Para, A., Parmaksiz, I., Pazos, A., Pelegrin, J., Maneiro, M. Pérez, Querol, M., Redwine, A. B., Renner, J., Rivilla, I., Rogero, C., Rogers, L., Romeo, B., Romo-Luque, C., Santos, F. P., Santos, J. M. F. dos, Seemann, M., Shomroni, I., Silva, P. A. O. C., Simón, A., Soleti, S. R., Sorel, M., Soto-Oton, J., Teixeira, J. M. R., Teruel-Pardo, S., Toledo, J. F., Tonnelé, C., Torrent, J., Trettin, A., Usón, A., Valle, P. R. G., Veloso, J. F. C. A., Waiton, J., and Yubero-Navarro, A.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment, Nuclear Experiment
Abstract

The imaging of individual Ba$^{2+}$ ions in high pressure xenon gas is one possible way to attain background-free sensitivity to neutrinoless double beta decay and hence establish the Majorana nature of the neutrino. In this paper we demonstrate selective single Ba$^{2+}$ ion imaging inside a high-pressure xenon gas environment. Ba$^{2+}$ ions chelated with molecular chemosensors are resolved at the gas-solid interface using a diffraction-limited imaging system with scan area of 1$\times$1~cm$^2$ located inside 10~bar of xenon gas. This new form of microscopy represents an important enabling step in the development of barium tagging for neutrinoless double beta decay searches in $^{136}$Xe, as well as a new tool for studying the photophysics of fluorescent molecules and chemosensors at the solid-gas interface.

Published
2024

3. Design, characterization and installation of the NEXT-100 cathode and electroluminescence regions

Author

NEXT Collaboration, Mistry, K., Rogers, L., Jones, B. J. P., Munson, B., Norman, L., Adams, C., Almazán, H., Álvarez, V., Aparicio, B., Aranburu, A. I., Arazi, L., Arnquist, I. J., Auria-Luna, F., Ayet, S., Azevedo, C. D. R., Bailey, K., Ballester, F., del Barrio-Torregrosa, M., Bayo, A., Benlloch-Rodríguez, J. M., Borges, F. I. G. M., Brodolin, A., Byrnes, N., Cárcel, S., Castillo, A., Cebrián, S., Church, E., Cid, L., Conde, C. A. N., Contreras, T., Cossío, F. P., Dey, E., Díaz, G., Dickel, T., Echevarria, C., Elorza, M., Escada, J., Esteve, R., Felkai, R., Fernandes, L. M. P., Ferrario, P., Ferreira, A. L., Foss, F. W., Freitas, E. D. C., Freixa, Z., Gómez-Cadenas, J. J., González, R., Grocott, J. W. R., Guenette, R., Hafidi, K., Hauptman, J., Henriques, C. A. O., Hernando~Morata, J. A., Herrero-Gómez, P., Herrero, V., Carrete, C. Hervés, Ifergan, Y., Larizgoitia, L., Larumbe, A., Lebrun, P., Lopez, F., López-March, N., Madigan, R., Mano, R. D. P., Marques, A. P., Martín-Albo, J., Martínez-Lema, G., Martínez-Vara, M., Meziani, Z. E., Miller, R. L., Molina-Canteras, J., Monrabal, F., Monteiro, C. M. B., Mora, F. J., Navarro, K. E., Novella, P., Nuñez, A., Nygren, D. R., Oblak, E., Oliver, D., Palacio, J., Palmeiro, B., Para, A., Parmaksiz, I., Pelegrin, J., Maneiro, M. Pérez, Querol, M., Redwine, A. B., Renner, J., Rivilla, I., Rogero, C., Romeo, B., Romo-Luque, C., Santos, F. P., Santos, J. M. F. dos, Seemann, M., Shomroni, I., Simón, A., Soleti, S. R., Sorel, M., Soto-Oton, J., Teixeira, J. M. R., Toledo, J. F., Torrent, J., Trettin, A., Usón, A., Veloso, J. F. C. A., Waiton, J., and Yubero, A.

Subjects
Physics - Instrumentation and Detectors
Abstract

NEXT-100 is currently being constructed at the Laboratorio Subterr\'aneo de Canfranc in the Spanish Pyrenees and will search for neutrinoless double beta decay using a high-pressure gaseous time projection chamber (TPC) with 100 kg of xenon. Charge amplification is carried out via electroluminescence (EL) which is the process of accelerating electrons in a high electric field region causing secondary scintillation of the medium proportional to the initial charge. The NEXT-100 EL and cathode regions are made from tensioned hexagonal meshes of 1 m diameter. This paper describes the design, characterization, and installation of these parts for NEXT-100. Simulations of the electric field are performed to model the drift and amplification of ionization electrons produced in the detector under various EL region alignments and rotations. Measurements of the electrostatic breakdown voltage in air characterize performance under high voltage conditions and identify breakdown points. The electrostatic deflection of the mesh is quantified and fit to a first-principles mechanical model. Measurements were performed with both a standalone test EL region and with the NEXT-100 EL region before its installation in the detector. Finally, we describe the parts as installed in NEXT-100, following their deployment in Summer 2023., Comment: 35 pages, 25 Figures, update includes accepted version in JINST

Published
2023
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4. Demonstration of Event Position Reconstruction based on Diffusion in the NEXT-White Detector

Author

Haefner, J., Navarro, K. E., Guenette, R., Jones, B. J. P., Tripathi, A., Adams, C., Almazán, H., Álvarez, V., Aparicio, B., Aranburu, A. I., Arazi, L., Arnquist, I. J., Auria-Luna, F., Ayet, S., Azevedo, C. D. R., Bailey, K., Ballester, F., del Barrio-Torregrosa, M., Bayo, A., BenllochRodríguez, J. M., Borges, F. I. G. M., Brodolin, A., Byrnes, N., Cárcel, S., Carrión, J. V., Cebrián, S., Church, E., Cid, L., Conde, C. A. N., Contreras, T., Cossío, F. P., Dey, E., Díaz, G., Dickel, T., Elorza, M., Escada, J., Esteve, R., Felkai, R., Fernandes, L. M. P., Ferrario, P., Ferreira, A. L., Foss, F. W., Freitas, E. D. C., Freixa, Z., Generowicz, J., Goldschmidt, A., Gómez-Cadenas, J. J., González, R., Grocott, J., Hafidi, K., Hauptman, J., Henriques, C. A. O., Morata, J. A. Hernando, Herrero-Gómez, P., Herrero, V., Carrete, C. Hervés, Ifergan, Y., Labarga, L., Larizgoitia, L., Larumbe, A., Lebrun, P., Lopez, F., López-March, N., Madigan, R., Mano, R. D. P., Marques, A. P., Martín-Albo, J., Martínez-Lema, G., Martínez-Vara, M., Meziani, Z. E., Miller, R. L., Mistry, K., Molina-Canteras, J., Monrabal, F., Monteiro, C. M. B., Mora, F. J., Vidal, J. Muñoz, Novella, P., Nuñez, A., Nygren, D. R., Oblak, E., Palacio, J., Palmeiro, B., Para, A., Parmaksiz, I., Pelegrin, J., Maneiro, M. Pérez, Querol, M., Redwine, A. B., Renner, J., Rivilla, I., Rodríguez, J., Rogero, C., Rogers, L., Romeo, B., Romo-Luque, C., Santos, F. P., Santos, J. M. F. dos, Shomroni, I., Simón, A., Soleti, S. R., Sorel, M., Soto-Oton, J., Teixeira, J. M. R., Toledo, J. F., Torrent, J., Trettin, A., Usón, A., Veloso, J. F. C. A., Waiton, J., and White, J. T.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

Noble element time projection chambers are a leading technology for rare event detection in physics, such as for dark matter and neutrinoless double beta decay searches. Time projection chambers typically assign event position in the drift direction using the relative timing of prompt scintillation and delayed charge collection signals, allowing for reconstruction of an absolute position in the drift direction. In this paper, alternate methods for assigning event drift distance via quantification of electron diffusion in a pure high pressure xenon gas time projection chamber are explored. Data from the NEXT-White detector demonstrate the ability to achieve good position assignment accuracy for both high- and low-energy events. Using point-like energy deposits from $^{83\mathrm{m}}$Kr calibration electron captures ($E\sim45$keV), the position of origin of low-energy events is determined to $2~$cm precision with bias $< 1$mm. A convolutional neural network approach is then used to quantify diffusion for longer tracks (E$\geq$1.5MeV), yielding a precision of 3cm on the event barycenter. The precision achieved with these methods indicates the feasibility energy calibrations of better than 1% FWHM at Q$_{\beta\beta}$ in pure xenon, as well as the potential for event fiducialization in large future detectors using an alternate method that does not rely on primary scintillation., Comment: 18 pages, 16 figures

Published
2023

5. Demonstration of event position reconstruction based on diffusion in the NEXT-white detector

Author

Haefner, J, Navarro, KE, Guenette, R, Jones, BJP, Tripathi, A, Adams, C, Almazán, H, Álvarez, V, Aparicio, B, Aranburu, AI, Arazi, L, Arnquist, IJ, Auria-Luna, F, Ayet, S, Azevedo, CDR, Bailey, K, Ballester, F, Barrio-Torregrosa, M del, Bayo, A, Benlloch-Rodríguez, JM, Borges, FIGM, Brodolin, A, Byrnes, N, Cárcel, S, Carrión, JV, Cebrián, S, Church, E, Cid, L, Conde, CAN, Contreras, T, Cossío, FP, Dey, E, Díaz, G, Dickel, T, Elorza, M, Escada, J, Esteve, R, Felkai, R, Fernandes, LMP, Ferrario, P, Ferreira, AL, Foss, FW, Freitas, EDC, Freixa, Z, Generowicz, J, Goldschmidt, A, Gómez-Cadenas, JJ, González, R, Grocott, J, Hafidi, K, Hauptman, J, Henriques, CAO, Morata, JA Hernando, Herrero-Gómez, P, Herrero, V, Hervés Carrete, C, Ifergan, Y, Labarga, L, Larizgoitia, L, Larumbe, A, Lebrun, P, Lopez, F, López-March, N, Madigan, R, Mano, RDP, Marques, AP, Martín-Albo, J, Martínez-Lema, G, Martínez-Vara, M, Meziani, ZE, Miller, RL, Mistry, K, Molina-Canteras, J, Monrabal, F, Monteiro, CMB, Mora, FJ, Muñoz Vidal, J, Novella, P, Nuñez, A, Nygren, DR, Oblak, E, Palacio, J, Palmeiro, B, Para, A, Parmaksiz, I, Pelegrin, J, Pérez Maneiro, M, Querol, M, Redwine, AB, Renner, J, Rivilla, I, Rodríguez, J, Rogero, C, Rogers, L, Romeo, B, Romo-Luque, C, Santos, FP, dos Santos, JMF, Shomroni, I, and Simón, A

Subjects
Nuclear and Plasma Physics, Synchrotrons and Accelerators, Physical Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics, Astronomical sciences, Atomic, molecular and optical physics, Particle and high energy physics
Abstract

Noble element time projection chambers are a leading technology for rare event detection in physics, such as for dark matter and neutrinoless double beta decay searches. Time projection chambers typically assign event position in the drift direction using the relative timing of prompt scintillation and delayed charge collection signals, allowing for reconstruction of an absolute position in the drift direction. In this paper, alternate methods for assigning event drift distance via quantification of electron diffusion in a pure high pressure xenon gas time projection chamber are explored. Data from the NEXT-White detector demonstrate the ability to achieve good position assignment accuracy for both high- and low-energy events. Using point-like energy deposits from 83mKr calibration electron captures (E∼45 keV), the position of origin of low-energy events is determined to 2 cm precision with bias

Published
2024

6. Demonstration of neutrinoless double beta decay searches in gaseous xenon with NEXT

Author

NEXT Collaboration, Novella, P., Sorel, M., Usón, A., Adams, C., Almazán, H., Álvarez, V., Aparicio, B., Aranburu, A. I., Arazi, L., Arnquist, I. J., Auria-Luna, F., Ayet, S., Azevedo, C. D. R., Bailey, K., Ballester, F., del Barrio-Torregrosa, M., Bayo, A., Benlloch-Rodríguez, J. M., Borges, F. I. G. M., Bounasser, S., Byrnes, N., Cárcel, S., Carrión, J. V., Cebrián, S., Church, E., Cid, L., Conde, C. A. N., Contreras, T., Cossío, F. P., Dey, E., Díaz, G., Dickel, T., Elorza, M., Escada, J., Esteve, R., Fahs, A., Felkai, R., Fernandes, L. M. P., Ferrario, P., Ferreira, A. L., Foss, F. W., Freitas, E. D. C., Freixa, Z., Generowicz, J., Goldschmidt, A., Gómez-Cadenas, J. J., González, R., Grocott, J., Guenette, R., Haefner, J., Hafidi, K., Hauptman, J., Henriques, C. A. O., Morata, J. A. Hernando, Herrero-Gómez, P., Herrero, V., Carrete, C. Hervés, Ho, J., Ho, P., Ifergan, Y., Jones, B. J. P., Labarga, L., Larizgoitia, L., Larumbe, A., Lebrun, P., Lopez, F., Gutierrez, D. Lopez, López-March, N., Madigan, R., Mano, R. D. P., Marques, A. P., Martín-Albo, J., Martínez-Lema, G., Martínez-Vara, M., Meziani, Z. E., Miller, R. L., Mistry, K., Molina-Canteras, J., Monrabal, F., Monteiro, C. M. B., Mora, F. J., Vidal, J. Muñoz, Navarro, K. E., Nuñez, A., Nygren, D. R., Oblak, E., Odriozola-Gimeno, M., Palacio, J., Palmeiro, B., Para, A., Parmaksiz, I., Pelegrin, J., Maneiro, M. Pérez, Querol, M., Redwine, A. B., Renner, J., Rivilla, I., Rodríguez, J., Rogero, C., Rogers, L., Romeo, B., Romo-Luque, C., Santos, F. P., Santos, J. M. F. dos, Simón, A., Soleti, S. R., Stanford, C., Teixeira, J. M. R., Toledo, J. F., Torrent, J., Veloso, J. F. C. A., Vuong, T. T., Waiton, J., and White, J. T.

Subjects
Nuclear Experiment, High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

The NEXT experiment aims at the sensitive search of the neutrinoless double beta decay in $^{136}$Xe, using high-pressure gas electroluminescent time projection chambers. The NEXT-White detector is the first radiopure demonstrator of this technology, operated in the Laboratorio Subterr\'aneo de Canfranc. Achieving an energy resolution of 1% FWHM at 2.6 MeV and further background rejection by means of the topology of the reconstructed tracks, NEXT-White has been exploited beyond its original goals in order to perform a neutrinoless double beta decay search. The analysis considers the combination of 271.6 days of $^{136}$Xe-enriched data and 208.9 days of $^{136}$Xe-depleted data. A detailed background modeling and measurement has been developed, ensuring the time stability of the radiogenic and cosmogenic contributions across both data samples. Limits to the neutrinoless mode are obtained in two alternative analyses: a background-model-dependent approach and a novel direct background-subtraction technique, offering results with small dependence on the background model assumptions. With a fiducial mass of only 3.50$\pm$0.01 kg of $^{136}$Xe-enriched xenon, 90% C.L. lower limits to the neutrinoless double beta decay are found in the T$_{1/2}^{0\nu}>5.5\times10^{23}-1.3\times10^{24}$ yr range, depending on the method. The presented techniques stand as a proof-of-concept for the searches to be implemented with larger NEXT detectors.

Published
2023
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7. NEXT-CRAB-0: A High Pressure Gaseous Xenon Time Projection Chamber with a Direct VUV Camera Based Readout

Author

NEXT Collaboration, Byrnes, N. K., Parmaksiz, I., Adams, C., Asaadi, J., Baeza-Rubio, J, Bailey, K., Church, E., González-Díaz, D., Higley, A., Jones, B. J. P., Mistry, K., Moya, I. A., Nygren, D. R., Oyedele, P., Rogers, L., Stogsdill, K., Almazán, H., Álvarez, V., Aparicio, B., Aranburu, A. I., Arazi, L., Arnquist, I. J., Ayet, S., Azevedo, C. D. R., Ballester, F., del Barrio-Torregrosa, M., Bayo, A., Benlloch-Rodríguez, J. M., Borges, F. I. G. M., Bounasser, S., Cárcel, S., Carrión, J. V., Cebrián, S., Cid, L., Conde, C. A. N., Contreras, T., Cossío, F. P., Dey, E., Díaz, G., Dickel, T., Elorza, M., Escada, J., Esteve, R., Fahs, A., Felkai, R., Fernandes, L. M. P., Ferrario, P., Ferreira, A. L., Foss, F. W., Freitas, E. D. C., Freixa, Z., Generowicz, J., Goldschmidt, A., Gómez-Cadenas, J. J., González, R., Grocott, J., Guenette, R., Haefner, J., Hafidi, K., Hauptman, J., Henriques, C. A. O., Morata, J. A. Hernando, Herrero-Gómez, P., Herrero, V., Carrete, C. Hervés, Ho, J., Ho, P., Ifergan, Y., Labarga, L., Larizgoitia, L., Lebrun, P., Lopez, F, Gutierrez, D. Lopez, López-March, N., Madigan, R., Mano, R. D. P., Marques, A. P., Martín-Albo, J., Martínez-Lema, G., Martínez-Vara, M., Meziani, Z. E., Miller, R. L., Monrabal, F., Monteiro, C. M. B., Mora, F. J., Vidal, J. Muñoz, Navarro, K. E., Novella, P., Nuñez, A., Oblak, E., Odriozola-Gimeno, M., Palacio, J., Palmeiro, B., Para, A., Pelegrin, J, Maneiro, M. Pérez, Querol, M., Redwine, A. B., Renner, J., Rivilla, I., Rodríguez, J., Rogero, C., Romeo, B., Romo-Luque, C., Santos, F. P., Santos, J. M. F. dos, Simón, A., Soleti, S. R., Sorel, M., Stanford, C., Teixeira, J. M. R., Toledo, J. F., Torrent, J., Usón, A., Veloso, J. F. C. A., Vuong, T. T., Waiton, J., and White, J. T.

Subjects
Physics - Instrumentation and Detectors
Abstract

The search for neutrinoless double beta decay ($0\nu\beta\beta$) remains one of the most compelling experimental avenues for the discovery in the neutrino sector. Electroluminescent gas-phase time projection chambers are well suited to $0\nu\beta\beta$ searches due to their intrinsically precise energy resolution and topological event identification capabilities. Scalability to ton- and multi-ton masses requires readout of large-area electroluminescent regions with fine spatial resolution, low radiogenic backgrounds, and a scalable data acquisition system. This paper presents a detector prototype that records event topology in an electroluminescent xenon gas TPC via VUV image-intensified cameras. This enables an extendable readout of large tracking planes with commercial devices that reside almost entirely outside of the active medium.Following further development in intermediate scale demonstrators, this technique may represent a novel and enlargeable method for topological event imaging in $0\nu\beta\beta$., Comment: 30 Pages, 22 figures, Updated to match current JINST submission

Published
2023

8. A Compact Dication Source for Ba$^{2+}$ Tagging and Heavy Metal Ion Sensor Development

Author

Navarro, K. E., Jones, B. J. P., Baeza-Rubio, J., Boyd, M., Denisenko, A. A., Foss, F. W., Giri, S., Miller, R., Nygren, D. R., Tiscareno, M. R., Samaniego, F. J., Stogsdill, K., Adams, C., Almazán, H., Álvarez, V., Aparicio, B., Aranburu, A. I., Arazi, L., Arnquist, I. J., Ayet, S., Azevedo, C. D. R., Bailey, K., Ballester, F., Benlloch-Rodríguez, J. M., Borges, F. I. G. M., Bounasser, S., Byrnes, N., Cárcel, S., Carrión, J. V., Cebrián, S., Church, E., Conde, C. A. N., Contreras, T., Cossío, F. P., Dey, E., Díaz, G., Dickel, T., Escada, J., Esteve, R., Fahs, A., Felkai, R., Fernandes, L. M. P., Ferrario, P., Ferreira, A. L., Freitas, E. D. C., Freixa, Z., Generowicz, J., Goldschmidt, A., Gómez-Cadenas, J. J., González, R., Grocott, J., Guenette, R., Haefner, J., Hafidi, K., Hauptman, J., Henriques, C. A. O., Morata, J. A. Hernando, Herrero-Gómez, P., Herrero, V., Carrete, C. Hervés, Ho, J., Ho, P., Ifergan, Y., Labarga, L., Larizgoitia, L., Lebrun, P., Gutierrez, D. Lopez, López-March, N., Madigan, R., Mano, R. D. P., Marques, A. P., Martín-Albo, J., Martínez-Lema, G., Martínez-Vara, M., Meziani, Z. E., Mistry, K., Monrabal, F., Monteiro, C. M. B., Mora, F. J., Vidal, J. Muñoz, Novella, P., Nuñez, A., Oblak, E., Odriozola-Gimeno, M., Palmeiro, B., Para, A., Pelegrín, J., Maneiro, M. Pérez, Querol, M., Redwine, A. B., Renner, J., Rivilla, I., Rodríguez, J., Rogero, C., Rogers, L., Romeo, B., Romo-Luque, C., Santos, F. P., Santos, J. M. F. dos, Simón, A., Sorel, M., Stanford, C., Teixeira, J. M. R., Toledo, J. F., Torrent, J., Usón, A., Veloso, J. F. C. A., Vuong, T. T., Waiton, J., and White, J. T.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment, Nuclear Experiment
Abstract

We present a tunable metal ion beam that delivers controllable ion currents in the picoamp range for testing of dry-phase ion sensors. Ion beams are formed by sequential atomic evaporation and single or multiple electron impact ionization, followed by acceleration into a sensing region. Controllability of the ionic charge state is achieved through tuning of electrode potentials that influence the retention time in the ionization region. Barium, lead, and cobalt samples have been used to test the system, with ion currents identified and quantified using a quadrupole mass analyzer. Realization of a clean $\mathrm{Ba^{2+}}$ ion beam within a bench-top system represents an important technical advance toward the development and characterization of barium tagging systems for neutrinoless double beta decay searches in xenon gas. This system also provides a testbed for investigation of novel ion sensing methodologies for environmental assay applications, with dication beams of Pb$^{2+}$ and Cd$^{2+}$ also demonstrated for this purpose.

Published
2023
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9. Demonstration of neutrinoless double beta decay searches in gaseous xenon with NEXT

Author

Novella, P., Sorel, M., Usón, A., Adams, C., Almazán, H., Álvarez, V., Aparicio, B., Aranburu, A. I., Arazi, L., Arnquist, I. J., Auria-Luna, F., Ayet, S., Azevedo, C. D. R., Bailey, K., Ballester, F., del Barrio-Torregrosa, M., Bayo, A., Benlloch-Rodríguez, J. M., Borges, F. I. G. M., Bounasser, S., Byrnes, N., Cárcel, S., Carrión, J. V., Cebrián, S., Church, E., Cid, L., Conde, C. A. N., Contreras, T., Cossío, F. P., Dey, E., Díaz, G., Dickel, T., Elorza, M., Escada, J., Esteve, R., Fahs, A., Felkai, R., Fernandes, L. M. P., Ferrario, P., Ferreira, A. L., Foss, F. W., Freitas, E. D. C., Freixa, Z., Generowicz, J., Goldschmidt, A., Gómez-Cadenas, J. J., González, R., Grocott, J., Guenette, R., Haefner, J., Hafidi, K., Hauptman, J., Henriques, C. A. O., Hernando Morata, J. A., Herrero-Gómez, P., Herrero, V., Hervés Carrete, C., Ho, J., Ho, P., Ifergan, Y., Jones, B. J. P., Labarga, L., Larizgoitia, L., Larumbe, A., Lebrun, P., Lopez, F., Lopez Gutierrez, D., López-March, N., Madigan, R., Mano, R. D. P., Marques, A. P., Martín-Albo, J., Martínez-Lema, G., Martínez-Vara, M., Meziani, Z. E., Miller, R. L., Mistry, K., Molina-Canteras, J., Monrabal, F., Monteiro, C. M. B., Mora, F. J., Muñoz Vidal, J., Navarro, K., Nuñez, A., Nygren, D. R., Oblak, E., Odriozola-Gimeno, M., Palacio, J., Palmeiro, B., Para, A., Parmaksiz, I., Pelegrin, J., Pérez Maneiro, M., Querol, M., Redwine, A. B., Renner, J., Rivilla, I., Rodríguez, J., Rogero, C., Rogers, L., Romeo, B., Romo-Luque, C., Santos, F. P., dos Santos, J. M. F., Simón, A., Soleti, S. R., Stanford, C., Teixeira, J. M. R., Toledo, J. F., Torrent, J., Veloso, J. F. C. A., Vuong, T. T., Waiton, J., and White, J. T.

Published
2023
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11. NEXT-CRAB-0: a high pressure gaseous xenon time projection chamber with a direct VUV camera based readout

Author

Byrnes, N.K., primary, Parmaksiz, I., additional, Adams, C., additional, Asaadi, J., additional, Baeza-Rubio, J., additional, Bailey, K., additional, Church, E., additional, González-Díaz, D., additional, Higley, A., additional, Jones, B.J.P., additional, Mistry, K., additional, Moya, I.A., additional, Nygren, D.R., additional, Oyedele, P., additional, Rogers, L., additional, Stogsdill, K., additional, Almazán, H., additional, Álvarez, V., additional, Aparicio, B., additional, Aranburu, A.I., additional, Arazi, L., additional, Arnquist, I.J., additional, Ayet, S., additional, Azevedo, C.D.R., additional, Ballester, F., additional, del Barrio-Torregrosa, M., additional, Bayo, A., additional, Benlloch-Rodríguez, J.M., additional, Borges, F.I.G.M., additional, Bounasser, S., additional, Cárcel, S., additional, Carrión, J.V., additional, Cebrián, S., additional, Cid, L., additional, Conde, C.A.N., additional, Contreras, T., additional, Cossío, F.P., additional, Dey, E., additional, Díaz, G., additional, Dickel, T., additional, Elorza, M., additional, Escada, J., additional, Esteve, R., additional, Fahs, A., additional, Felkai, R., additional, Fernandes, L.M.P., additional, Ferrario, P., additional, Ferreira, A.L., additional, Foss, F.W., additional, Freitas, E.D.C., additional, Freixa, Z., additional, Generowicz, J., additional, Goldschmidt, A., additional, Gómez-Cadenas, J.J., additional, González, R., additional, Grocott, J., additional, Guenette, R., additional, Haefner, J., additional, Hafidi, K., additional, Hauptman, J., additional, Henriques, C.A.O., additional, Hernando Morata, J.A., additional, Herrero-Gómez, P., additional, Herrero, V., additional, Hervés Carrete, C., additional, Ho, J., additional, Ho, P., additional, Ifergan, Y., additional, Labarga, L., additional, Larizgoitia, L., additional, Lebrun, P., additional, Lopez, F., additional, Lopez Gutierrez, D., additional, López-March, N., additional, Madigan, R., additional, Mano, R.D.P., additional, Marques, A.P., additional, Martín-Albo, J., additional, Martínez-Lema, G., additional, Martínez-Vara, M., additional, Meziani, Z.E., additional, Miller, R.L., additional, Monrabal, F., additional, Monteiro, C.M.B., additional, Mora, F.J., additional, Muñoz Vidal, J., additional, Navarro, K.E., additional, Novella, P., additional, Nuñez, A., additional, Oblak, E., additional, Odriozola-Gimeno, M., additional, Palacio, J., additional, Palmeiro, B., additional, Para, A., additional, Pelegrin, J., additional, Pérez Maneiro, M., additional, Querol, M., additional, Redwine, A.B., additional, Renner, J., additional, Rivilla, I., additional, Rodríguez, J., additional, Rogero, C., additional, Romeo, B., additional, Romo-Luque, C., additional, Santos, F.P., additional, dos Santos, J.M.F., additional, Simón, A., additional, Soleti, S.R., additional, Sorel, M., additional, Stanford, C., additional, Teixeira, J.M.R., additional, Toledo, J.F., additional, Torrent, J., additional, Usón, A., additional, Veloso, J.F.C.A., additional, Vuong, T.T., additional, Waiton, J., additional, and White, J.T., additional

Published
2023
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12. A compact dication source for Ba2+ tagging and heavy metal ion sensor development

Author

Navarro, K.E., primary, Baeza-Rubio, J., additional, Boyd, M., additional, Foss, F.W., additional, Giri, S., additional, Jones, B.J.P., additional, Miller, R.L., additional, Nygren, D.R., additional, Samaniego, F.J., additional, Stogsdill, K., additional, Tiscareno, M.R., additional, Adams, C., additional, Almazán, H., additional, Álvarez, V., additional, Aparicio, B., additional, Aranburu, A.I., additional, Arazi, L., additional, Arnquist, I.J., additional, Ayet, S., additional, Azevedo, C.D.R., additional, Bailey, K., additional, Ballester, F., additional, del Barrio-Torregrosa, M., additional, Bayo, A., additional, Benlloch-Rodríguez, J.M., additional, Borges, F.I.G.M., additional, Bounasser, S., additional, Byrnes, N., additional, Cárcel, S., additional, Carrión, J.V., additional, Cebrián, S., additional, Church, E., additional, Cid, L., additional, Conde, C.A.N., additional, Contreras, T., additional, Cossío, F.P., additional, Dey, E., additional, Díaz, G., additional, Dickel, T., additional, Elorza, M., additional, Escada, J., additional, Esteve, R., additional, Fahs, A., additional, Felkai, R., additional, Fernandes, L.M.P., additional, Ferrario, P., additional, Ferreira, A.L., additional, Freitas, E.D.C., additional, Freixa, Z., additional, Generowicz, J., additional, Goldschmidt, A., additional, Gómez-Cadenas, J.J., additional, González, R., additional, Grocott, J., additional, Guenette, R., additional, Haefner, J., additional, Hafidi, K., additional, Hauptman, J., additional, Henriques, C.A.O., additional, Hernando Morata, J.A., additional, Herrero-Gómez, P., additional, Herrero, V., additional, Hervés Carrete, C., additional, Ho, J., additional, Ho, P., additional, Ifergan, Y., additional, Labarga, L., additional, Larizgoitia, L., additional, Lebrun, P., additional, Lopez, F., additional, Lopez Gutierrez, D., additional, López-March, N., additional, Madigan, R., additional, Mano, R.D.P., additional, Marques, A.P., additional, Martín-Albo, J., additional, Martínez-Lema, G., additional, Martínez-Vara, M., additional, Meziani, Z.E., additional, Mistry, K., additional, Monrabal, F., additional, Monteiro, C.M.B., additional, Mora, F.J., additional, Muñoz Vidal, J., additional, Novella, P., additional, Nuñez, A., additional, Oblak, E., additional, Odriozola-Gimeno, M., additional, Palacio, J., additional, Palmeiro, B., additional, Para, A., additional, Parmaksiz, I., additional, Pelegrin, J., additional, Pérez Maneiro, M., additional, Querol, M., additional, Redwine, A.B., additional, Renner, J., additional, Rivilla, I., additional, Rodríguez, J., additional, Rogero, C., additional, Rogers, L., additional, Romeo, B., additional, Romo-Luque, C., additional, Santos, F.P., additional, dos Santos, J.M.F., additional, Simón, A., additional, Soleti, S.R., additional, Sorel, M., additional, Stanford, C., additional, Teixeira, J.M.R., additional, Toledo, J.F., additional, Torrent, J., additional, Usón, A., additional, Veloso, J.F.C.A., additional, Vuong, T.T., additional, Waiton, J., additional, and White, J.T., additional

Published
2023
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16. Phenotypic correlations in a large single‐center cohort of patients with BSCL2 nerve disorders: a clinical, neurophysiological and muscle magnetic resonance imaging study

Author

Fernández‐Eulate, G., primary, Fernández‐Torrón, R., additional, Guisasola, A., additional, Gaspar, M. T. I., additional, Diaz‐Manera, J., additional, Maneiro, M., additional, Zulaica, M., additional, Olasagasti, V., additional, Formica, A. F., additional, Espinal, J. B., additional, Ruiz, M., additional, Schlüter, A., additional, Pujol, A., additional, Poza, J. J., additional, and López de Munain, A., additional

Published
2020
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26. Chemo- and Regioselective Lysine Modification on Native Proteins

Author

Matos, M.J., Oliveira, B.L., Martínez-Sáez, N., Guerreiro, A., Cal, P.M.S.D., Bertoldo, J., Maneiro, M., Perkins, E., Howard, J., Deery, M.J., Chalker, J.M., Corzana, F., Jiménez-Osés, G., and Bernardes, G.J.L.

Abstract

Site-selective chemical conjugation of synthetic molecules to proteins expands their functional and therapeutic capacity. Current protein modification methods, based on synthetic and biochemical technologies, can achieve site selectivity, but these techniques often require extensive sequence engineering or are restricted to the N- or C-terminus. Here we show the computer-assisted design of sulfonyl acrylate reagents for the modification of a single lysine residue on native protein sequences. This feature of the designed sulfonyl acrylates, together with the innate and subtle reactivity differences conferred by the unique local microenvironment surrounding each lysine, contribute to the observed regioselectivity of the reaction. Moreover, this site selectivity was predicted computationally, where the lysine with the lowest pKa was the kinetically favored residue at slightly basic pH. Chemoselectivity was also observed as the reagent reacted preferentially at lysine, even in those cases when other nucleophilic residues such as cysteine were present. The reaction is fast and proceeds using a single molar equivalent of the sulfonyl acrylate reagent under biocompatible conditions (37 °C, pH 8.0). This technology was demonstrated by the quantitative and irreversible modification of five different proteins including the clinically used therapeutic antibody Trastuzumab without prior sequence engineering. Importantly, their native secondary structure and functionality is retained after the modification. This regioselective lysine modification method allows for further bioconjugation through aza-Michael addition to the acrylate electrophile that is generated by spontaneous elimination of methanesulfinic acid upon lysine labeling. We showed that a protein-antibody conjugate bearing a site-specifically installed fluorophore at lysine could be used for selective imaging of apoptotic cells and detection of Her2+ cells, respectively. This simple, robust method does not require genetic engineering and may be generally used for accessing diverse, well-defined protein conjugates for basic biology and therapeutic studies. © 2018 American Chemical Society.

Published
2018

31. Self-organization of photo-active nanostructures: general discussions

Author

Pikramenou, Z, Weinstein, J, Pan, Q., Lewis, F, Bassani, D.M., Würthner, F, Moucheron, Cécile, Slota, M, Díaz-Moscoso, A, Karlsson, J, Basilio, N, Adams, David, Scandola, F, Bohne, C, Lemon, C, Campagna, Sebastiano, Rohacova, J, Ohashi, K, Plötz, P.A., Monti, F, Kelly, J.M., Keane, P, Gibson, E, Lemercier, G, Ruggi, A, Cucinotta, F, Gust, D, Bradberry, S, Vos, Johannes G., Pistolis, G, Mauro, M, Tuite, E, De Cola, L, Ceroni, P, Maneiro, M, Galoppini, E, Gunnlaugsson, T, Pikramenou, Z, Weinstein, J, Pan, Q., Lewis, F, Bassani, D.M., Würthner, F, Moucheron, Cécile, Slota, M, Díaz-Moscoso, A, Karlsson, J, Basilio, N, Adams, David, Scandola, F, Bohne, C, Lemon, C, Campagna, Sebastiano, Rohacova, J, Ohashi, K, Plötz, P.A., Monti, F, Kelly, J.M., Keane, P, Gibson, E, Lemercier, G, Ruggi, A, Cucinotta, F, Gust, D, Bradberry, S, Vos, Johannes G., Pistolis, G, Mauro, M, Tuite, E, De Cola, L, Ceroni, P, Maneiro, M, Galoppini, E, and Gunnlaugsson, T

Abstract

info:eu-repo/semantics/published

Published
2015

36. Desgaste de materiales compuestos Al-Li/SiC

Author

Rodríguez,J., Poza,P., Maneiro,M. A. Garrido, and Rico,A.

Subjects
metal - matrix composites, Desgaste por deslizamiento, sliding wear, capas de aleación mecánica, materiales compuestos de matriz metálica, temperature effect, efecto de la temperatura, mechanically mixed layers (mml)
Abstract

Los materiales compuestos de matriz de aluminio reforzados con partículas cerámicas presentan mejores propiedades que las correspondientes aleaciones sin reforzar. La resistencia al desgaste es una de las propiedades que se ven más afectadas por la presencia del refuerzo. En este trabajo se ha realizado un estudio comparativo del comportamiento frente al desgaste por deslizamiento de material compuesto de matriz de aluminio-litio (Al - 8090) reforzado con un 15 % en volumen de partículas de carburo de silicio y la correspondiente aleación sin reforzar. Los resultados experimentales corresponden a ensayos de punzón sobre disco (pin on disc) en los que se ha variado la carga normal y la temperatura. A pesar de lo que inicialmente podría esperarse, el material sin reforzar se comporta mejor que el material compuesto en condiciones de desgaste suave. Sin embargo, cuando las condiciones de desgaste son más exigentes (alta temperatura y elevada presión) el material compuesto presenta una mayor resistencia al desgaste que el material sin reforzar. Las partículas del refuerzo estabilizan térmicamente la aleación de aluminio-litio y como consecuencia de ello, la temperatura de transición entre el régimen de desgaste suave y el de desgaste severo es más elevada en el material compuesto que en la aleación sin reforzar. Aluminium matrix composites reinforced with ceramic particles exhibit better properties than the corresponding unreinforced alloys, particularly the wear resistance. This work presents a comparative study of the sliding wear behaviour of an aluminium-lithium (Al-8090) composite material reinforced with silicon carbide particles (15% in vol.) and the unreinforced alloy. The experimental results were obtained from pin on disc tests where the normal load and the temperature were varied. The material without reinforcement behaves better than the composite material under mild wear conditions. Nevertheless, in the severe wear regime (high temperature and high pressure) the composite wear resistance is higher than that of the unreinforced alloy. The particles of the reinforcement stabilize thermally the aluminium-lithium alloy and their mechanical properties remain at higher temperatures. For that reason, the transition temperature from mild to severe wear is higher in the composite material than in the unreinforced alloy.

Published
2006

40. Análisis comparativo de las propiedades mecánicas determinadas con técnicas de nanoindentación

Author

Garrido-Maneiro, M. A., Lopez-Galisteo, A. J., and Rodriguez, J.

Subjects
Nanoindentación, recubrimientos de níquel, Ttermal sprayed nickel coatings, Nanoindentation
Abstract

Mechanical properties obtained through nanoindentation tests have been compared to those provided by the traditional tensile tests. Due to the small dimensions of the coatings, two bulk aluminium alloys with different elastic constants, yield strength and hardening index were tested. The nanoindentation technique was also applied to characterize thermal sprayed nitrogen (Ni) coatings. En este trabajo se analizan las posibilidades de la nanoindentación para caracterizar el comportamiento mecánico de un material, comparando sus resultados con los que proporciona el ensayo de tracción convencional. Dada la imposibilidad de fabricar probetas de tracción a partir de recubrimientos, se han empleado como materiales de referencia dos aleaciones de aluminio con valores diferentes de módulo elástico, límite elástico e índice de endurecimiento. Posteriormente, la técnica se ha empleado en la caracterización de materiales base níquel depositados por proyección térmica.

Published
2004
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41. Structure of Salmonella typhi type I dehydroquinase irreversibly inhibited with a 1,3,4-trihydroxyciclohexane-1-carboxylic acid derivative

Author

Otero, J.M., primary, Llamas-Saiz, A.L., additional, Tizon, L., additional, Maneiro, M., additional, Lence, E., additional, Poza, S., additional, Lamb, H., additional, Hawkins, A.R., additional, Blanco, B., additional, Sedes, A., additional, Peon, A., additional, Gonzalez-Bello, C., additional, and van Raaij, M.J., additional

Published
2014
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