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Your search keyword '"Mandel, Irina A"' showing total 27 results
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27 results on '"Mandel, Irina A"'

1. Potential for the lung recruitment and the risk of lung overdistension during 21 days of mechanical ventilation in patients with  COVID-19 after noninvasive ventilation failure: the COVID-VENT observational trial

Author

Yaroshetskiy, Andrey I., Avdeev, Sergey N., Politov, Mikhail E., Nogtev, Pavel V., Beresneva, Victoria G., Sorokin, Yury D., Konanykhin, Vasily D., Krasnoshchekova, Anna P., Merzhoeva, Zamira M., Tsareva, Natalia A., Trushenko, Natalia V., Mandel, Irina A., and Yavorovskiy, Andrey G.

Published
2022
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11. Additional file 4 of Potential for the lung recruitment and the risk of lung overdistension during 21 days of mechanical ventilation in patients with COVID-19 after noninvasive ventilation failure: the COVID-VENT observational trial

Author

Yaroshetskiy, Andrey I., Avdeev, Sergey N., Politov, Mikhail E., Nogtev, Pavel V., Beresneva, Victoria G., Sorokin, Yury D., Konanykhin, Vasily D., Krasnoshchekova, Anna P., Merzhoeva, Zamira M., Tsareva, Natalia A., Trushenko, Natalia V., Mandel, Irina A., and Yavorovskiy, Andrey G.

Abstract

Additional file 4. ROC curves for mortality prediction for the ventilation status parameters on Day 10

Published
2022
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12. Additional file 3 of Potential for the lung recruitment and the risk of lung overdistension during 21 days of mechanical ventilation in patients with COVID-19 after noninvasive ventilation failure: the COVID-VENT observational trial

Author

Yaroshetskiy, Andrey I., Avdeev, Sergey N., Politov, Mikhail E., Nogtev, Pavel V., Beresneva, Victoria G., Sorokin, Yury D., Konanykhin, Vasily D., Krasnoshchekova, Anna P., Merzhoeva, Zamira M., Tsareva, Natalia A., Trushenko, Natalia V., Mandel, Irina A., and Yavorovskiy, Andrey G.

Subjects
respiratory system, circulatory and respiratory physiology, respiratory tract diseases
Abstract

Additional file 3. ROC curve for mortality prediction for arterial oxygen partial pressure to the fraction of inspiratory oxygen ratio (PaO2/FiO2) on Day 7

Published
2022
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14. INFLUENCE OF RESPIRATORY SUPPORT STRATEGY DURING CARDIOPULMONARY BYPASS ON LUNGS OXYGENATING FUNCTION

Author

Kirillov, Aleksandr, primary, Yavorovskiy, Andrey, additional, Mandel, Irina, additional, Vyzhigina, Margarita, additional, Komarov, Roman, additional, Nogtev, Pavel, additional, Bagdasarov, Pavel, additional, Khalikova, Elena, additional, Podolskiy, Yuri, additional, Panov, Aleksandr, additional, Kazakova, Sofia, additional, and Kasim, Timur, additional

Published
2021
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18. Long-Term Protective Effects of Single-Dose infusion of Warm Blood Cardioplegic Solution in a mini-pig model on the background of intraoperative anemia

Author

Yavorovskiy, Andrey G., primary, Komarov, Roman N., additional, Kogan, Evgenia A., additional, Mandel, Irina A., additional, Panov, Alexander V., additional, Bagdasarov, Pavel S., additional, Bulanova, Ekaterina L., additional, Khalikova, Elena Yu., additional, and Popov, Alexander M., additional

Published
2021
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19. Potential for the Lung Recruitment and the Risk of Lung Overdistension During 21 Days of Mechanical Ventilation in Patients With COVID-19 After Noninvasive Ventilation Failure: the COVID-VENT Observational Trial

Author

Yaroshetskiy, Andrey, primary, Avdeev, Sergey N., additional, Politov, Mikhail E., additional, Nogtev, Pavel V., additional, Beresneva, Victoria G., additional, Sorokin, Yury D., additional, Konanykhin, Vasily D., additional, Krasnoshchekova, Anna P., additional, Merzhoeva, Zamira M., additional, Tsareva, Natalia A., additional, Trushenko, Natalia V., additional, Mandel, Irina A., additional, and Yavorovskiy, Andrey G., additional

Published
2021
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22. Influence of Hypoxic and Hyperoxic Preconditioning on Endothelial Function in a Model of Myocardial Ischemia-Reperfusion Injury with Cardiopulmonary Bypass (Experimental Study)

Author

Mandel, Irina A., primary, Podoksenov, Yuri K., additional, Suhodolo, Irina V., additional, An, Darya A., additional, Mikheev, Sergey L., additional, Podoksenov, Andrey Yu., additional, Svirko, Yulia S., additional, Gusakova, Anna M., additional, Shipulin, Vladimir M., additional, and Yavorovskiy, Andrey G., additional

Published
2020
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27. Abstract 11400: Nitric Oxide Exerts Organoprotective Effects in Cardiac Surgery.

Author

Kamenshchikov, Nikolay O, Mandel, Irina A, Podoksenov, Yuri K, Svirko, Yulia S, Lomivorotov, Vladimir V, Mikheev, Sergey L, Kozlov, Boris N, Nenakhova, Aleksandra A, Anfinogenova, Yana, Shipulin, Vladimir M, and Atochin, Dmitriy N

Subjects
*CARDIAC surgery, *ARTIFICIAL blood circulation, *NITRIC oxide, *CARDIOPULMONARY bypass, *TROPONIN I, *POSTOPERATIVE period
Abstract

Introduction: Nitric oxide (NO) signaling is involved in the mechanisms of organoprotection during ischemia and reperfusion. Hypothesis: We assessed the hypothesis that NO supply to the extracorporeal circulation circuit exerts organoprotective effects during cardiac surgery with cardiopulmonary bypass (CPB). Methods: A total of 71 patients were randomly allocated to undergo standard CPB-based cardiac surgery (control group) or surgery where 40-ppm NO was added to CPB circuit (NO-group). Four subgroups were assigned to study cardio- or nephroprotective properties of NO administration. Two clinical trials were registered as ClinicalTrials.gov: (#NCT03527381 and #NCT03500783). Cardiac troponin I (cTnI), creatine kinase-muscle/brain (CK-MB), vasoactive inotropic score (VIS), frequency of acute kidney injury (AKI), diuresis during CPB, urine neutrophil gelatinase-associated lipocalin (uNGAL) level, cumulative hydrobalance, diuresis, Lasix doses, and serum creatinine dynamics were studied. Results: cTnI level was lower in NO-group compared to control 6 h after surgery: 1.8±0.4 vs 2.4±0.6 ng/mL (p=0.001). CK-MB was lower in NO-group compared to control 24 h after surgery: 47.7±8.1 vs 62.3±9.8 U/L (р=0.001). VIS was significantly lower in NO-group 6 h after surgery. AKI rate significantly decreased: 14.3% in NO-group vs 44.4% in control group (р=0.0053). Stage-2 AKI was absent in NO-group, but not in control group (4 cases). Diuresis was higher in NO-group (р=0.0003). Compared to baseline, uNGAL level was lower in NO-group 4 h after surgery (р=0.007). In control group, creatinine level at 24 h significantly exceeded baseline value (р=0.0006) and remained increased for up to 5 days after surgery (р=0.03). Creatinine level in NO-group did not change during early postoperative period compared to baseline. Cumulative hydrobalance, diuresis, Lasix doses, and complication rates did not differ between groups after surgery. Conclusions: NO supply to CPB circuit during cardiac surgery exerted organoprotective effects. This work was supported, in part, by the Russian State Project "Science" (AAAA-A15-115123110026-3). [ABSTRACT FROM AUTHOR]

Published
2018

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