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1. Diabetes Self-management Education and Support in Adults With Type 2 Diabetes: A Consensus Report of the American Diabetes Association, the Association of Diabetes Care and Education Specialists, the Academy of Nutrition and Dietetics, the American Academy of Family Physicians, the American Academy of PAs, the American Association of Nurse Practitioners, and the American Pharmacists Association

Author

Powers, Margaret A., Bardsley, Joan K., Cypress, Marjorie, Funnell, Martha M., Harms, Dixie, Hess-Fischl, Amy, Hooks, Beulette, Isaacs, Diana, Mandel, Ellen D., Maryniuk, Melinda D., Norton, Anna, Rinker, Joanne, Siminerio, Linda M., and Uelmen, Sacha

Published
2021
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5. Diabetes self-management education and support in adults with type 2 diabetes: A consensus report of the American Diabetes Association, the Association of Diabetes Care and Education Specialists, the Academy of Nutrition and Dietetics, the American Academy of Family Physicians, the American Academy of PAs, the American Association of Nurse Practitioners, and the American Pharmacists Association

Author

Powers, Margaret A., Bardsley, Joan K., Cypress, Marjorie, Funnell, Martha M., Harms, Dixie, Hess-Fischl, Amy, Hooks, Beulette, Isaacs, Diana, Mandel, Ellen D., Maryniuk, Melinda D., Norton, Anna, Rinker, Joanne, Siminerio, Linda M., and Uelmen, Sacha

Published
2020
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9. Polypharmacy in the Elderly: How to Reduce Adverse Drug Events

Author

Barclay, Kelsey, Frassetto, Amy, Robb, Julie, and Mandel, Ellen D.

Subjects
Elderly patients -- Drug therapy, Adverse drug reactions -- Risk factors -- Prevention, Polypharmacy -- Complications and side effects, Health
Abstract

Managing medications in the elderly can be complicated by the physiologic effects of aging and the prevalence of comorbidities. Consistent use of tools such as the Beers criteria and the [...]

Published
2018

18. Contributors

Author

Baroody, Fuad M., primary, Bearelly, Shethal, additional, Bhrany, Amit D., additional, Brietzke, Scott, additional, Brinkmeier, Jennifer Veraldi, additional, Brown, David J., additional, Casselbrandt, Margaretha L., additional, Chan, Kenny, additional, Chen, Eunice Y., additional, Cheng, Alan G., additional, Chiang, Tendy, additional, Choi, Sukgi S., additional, Chun, Robert, additional, Cotton, Robin T., additional, Daniel, Sam J., additional, Demke, Joshua C., additional, Denoyelle, Françoise, additional, Derkay, Craig S., additional, Elluru, Ravindhra G., additional, Fandiño Cardenas, Marcela, additional, Faust, Russell A., additional, Goldstein, Nira A., additional, Green, Glenn, additional, Gries, Heike, additional, Handelsman, Jaynee A., additional, Heider, Amer, additional, Ishman, Stacey L., additional, Jackler, Robert K., additional, Kanaan, Alyssa A., additional, Kepchar, Jessica, additional, Koh, Jeffrey, additional, Kozak, Frederick K., additional, Lefton-Greif, Maureen A., additional, Lesperance, Marci M., additional, Mandel, Ellen M., additional, McMurray, J. Scott, additional, Meier, Jeremy D., additional, Messner, Anna H., additional, Meyer, Anna, additional, Milczuk, Henry A., additional, Muntz, Harlan, additional, Murakami, Craig S., additional, Nelson, Marc, additional, Noel, Richard J., additional, Ohye, Richard, additional, Ospina, Juan Camilo, additional, Perkins, Jonathan A., additional, Potsic, William P., additional, Rizzi, Mark D., additional, Rosbe, Kristina W., additional, Sauder, Cara, additional, Schoem, Scott R., additional, Sie, Kathleen C.Y., additional, Smith, Marshall E., additional, Swanson, Veronica C., additional, Taneja, Pravin A., additional, Tatum, Sherard A., additional, Truong, Mai Thy, additional, Van Riper, Lori A., additional, Wang, Tom D., additional, Wetmore, Ralph F., additional, Yellon, Robert F., additional, and Zalzal, George H., additional

Published
2015
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21. Ebola: lessons from the latest pandemic

Author

Silver, Catherine B., Leon, Erin L., Zaino, Sarah A., and Mandel, Ellen D.

Subjects
Epidemics -- Control, Ebola virus infections -- Risk factors -- Care and treatment -- Diagnosis, Physicians -- Practice, Symptomatology -- Analysis, Physiology, Pathological -- Analysis, Health
Abstract

The 2014 re-emergence of Ebola virus disease (EVD) quickly became the largest and deadliest outbreak of the disease ever recorded. Originating in Guinea, it spread to neighboring countries and others [...]

Published
2015

26. Colorectal cancer screening: what's accurate and cost-effective?

Author

Mueller, Carolyn, Perry, Molly, DeCicco, Lisa, and Mandel, Ellen D.

Subjects
Cancer -- Diagnosis, Colorectal cancer -- Health aspects, Health, American Cancer Society
Abstract

Because colorectal cancer is often asymptomatic, routine screening is essential to detect lesions at an early stage. The evolution of health care has brought new and improved screening methods for [...]

Published
2013

27. Diabetes Self-management Education and Support in Adults With Type 2 Diabetes: A Consensus Report of the American Diabetes Association, the Association of Diabetes Care & Education Specialists, the Academy of Nutrition and Dietetics, the American Academy of Family Physicians, the American Academy of PAs, the American Association of Nurse Practitioners, and the American Pharmacists Association

Author

Powers, Margaret A., primary, Bardsley, Joan K., additional, Cypress, Marjorie, additional, Funnell, Martha M., additional, Harms, Dixie, additional, Hess-Fischl, Amy, additional, Hooks, Beulette, additional, Isaacs, Diana, additional, Mandel, Ellen D., additional, Maryniuk, Melinda D., additional, Norton, Anna, additional, Rinker, Joanne, additional, Siminerio, Linda M., additional, and Uelmen, Sacha, additional

Published
2021
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28. dci20_0023_Supplementary_rev2 – Supplemental material for Diabetes Self-management Education and Support in Adults With Type 2 Diabetes: A Consensus Report of the American Diabetes Association, the Association of Diabetes Care & Education Specialists, the Academy of Nutrition and Dietetics, the American Academy of Family Physicians, the American Academy of PAs, the American Association of Nurse Practitioners, and the American Pharmacists Association

Author

Powers, Margaret A., Bardsley, Joan K., Cypress, Marjorie, Funnell, Martha M., Harms, Dixie, Hess-Fischl, Amy, Beulette Hooks, Isaacs, Diana, Mandel, Ellen D., Maryniuk, Melinda D., Norton, Anna, Rinker, Joanne, Siminerio, Linda M., and Uelmen, Sacha

Subjects
111099 Nursing not elsewhere classified, FOS: Clinical medicine, 111199 Nutrition and Dietetics not elsewhere classified, 111799 Public Health and Health Services not elsewhere classified, 160807 Sociological Methodology and Research Methods, FOS: Health sciences, 110306 Endocrinology, FOS: Sociology
Abstract

Supplemental material, dci20_0023_Supplementary_rev2 for Diabetes Self-management Education and Support in Adults With Type 2 Diabetes: A Consensus Report of the American Diabetes Association, the Association of Diabetes Care & Education Specialists, the Academy of Nutrition and Dietetics, the American Academy of Family Physicians, the American Academy of PAs, the American Association of Nurse Practitioners, and the American Pharmacists Association by Margaret A. Powers, Joan K. Bardsley, Marjorie Cypress, Martha M. Funnell, Dixie Harms, Amy Hess-Fischl, Beulette Hooks, Diana Isaacs, Ellen D. Mandel, Melinda D. Maryniuk, Anna Norton, Joanne Rinker, Linda M. Siminerio and Sacha Uelmen in The Diabetes Educator

Published
2020
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31. Temporal relationships between colds, upper respiratory viruses detected by polymerase chain reaction, and otitis media in young children followed through a typical cold season

Author

Winther, Birgit, Alper, Cuneyt M., Mandel, Ellen M., Doyle, William J., and Hendley, J. Owen

Subjects
Respiratory tract diseases -- Research, Respiratory tract diseases -- Risk factors, Respiratory tract diseases -- Care and treatment, Respiratory tract diseases -- Analysis, Cold (Disease) in children -- Risk factors, Cold (Disease) in children -- Care and treatment, Cold (Disease) in children -- Analysis, Children -- Health aspects, Children -- Research, Children -- Analysis
Abstract

INTRODUCTION. Otitis media is a frequent complication of a viral upper respiratory tract infection, and the reported co-incidence of those diseases increases with assay sensitivity and sampling density. We determined the incidence of otitis-media complications in young children when referenced to cold-like illnesses and to concurrent virus recovery from the nasopharynx. METHODS. A total of 60 children from 24 families were followed from October 2003 through April 30, 2004, by daily parental recording of illness signs, weekly pneumatic otoscopic examinations, and periodic polymerase chain reaction assay of collected nasal fluids for common viruses. RESULTS. One hundred ninety-nine cold-like illnesses were observed, but a sample for virus assay was not collected concurrent with 71 episodes. Of the remainder, 73% of cold-like illnesses were temporally related to recovery of 1 or a combination of the assayed viruses, with rhinovirus predominating. For non-cold-like illness periods, 54 (18%) of 297 assays were positive for virus, and the virus frequency distribution was similar to that for cold-like illnesses. There were 93 diagnosed otitis-media episodes; 65 (70%) of these occurred during a cold-like illness. For the 79 otitis-media episodes with available nasal samples, 61 (77%) were associated with a positive virus result. In this population, the otitis-media complication rate for a cold-like illness was 33%. CONCLUSIONS. A cold-like illness was not a prerequisite for po]ymerase chain reaction detection of viruses in the nose and nasopharynx of young children. Viral detection by polymerase chain reaction in the absence of a cold-like illness is associated with complications in some subjects. Otitis media is a complication of viral infection both with and without concurrent cold-like illnesses, thus downwardly biasing coincidence estimates that use cold-based illnesses as the denominator. Key Words colds, children, otitis media, virus, It is commonly accepted that viral upper respiratory tract infection (vURI) is causally related to the development of new episodes of otitis media (OM). (1-3) However, disagreements exist as to [...]

Published
2007

32. Diabetes Self-management Education and Support in Adults With Type 2 Diabetes: A Consensus Report of the American Diabetes Association, the Association of Diabetes Care & Education Specialists, the Academy of Nutrition and Dietetics, the American Academy of Family Physicians, the American Academy of PAs, the American Association of Nurse Practitioners, and the American Pharmacists Association

Author

Powers, Margaret A., primary, Bardsley, Joan K., additional, Cypress, Marjorie, additional, Funnell, Martha M., additional, Harms, Dixie, additional, Hess-Fischl, Amy, additional, Hooks, Beulette, additional, Isaacs, Diana, additional, Mandel, Ellen D., additional, Maryniuk, Melinda D., additional, Norton, Anna, additional, Rinker, Joanne, additional, Siminerio, Linda M., additional, and Uelmen, Sacha, additional

Published
2020
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34. Pediatric GERD: diagnosis and management

Author

Mandel, Ellen D., Ashforth, Claudia, and Daugherty, Kristine

Subjects
Gastroesophageal reflux -- Care and treatment, Health
Abstract

As with US adults, infants and children appear to be at increased risk for gastroesophageal reflux disease (GERD). Lacking a cardinal symptom in children and often linked with confounding extra-esophageal [...]

Published
2013

37. Contributors

Author

Abuzeid, Waleed M., primary, Adams, Meredith E., additional, Adamson, Peter A., additional, Adenis, Antoine, additional, Akst, Seth, additional, Albers, Sheri L., additional, Albert, David, additional, Alexander, Ronda E., additional, Archbold, Sue, additional, Armstrong, William B., additional, Arriaga, Moisés A., additional, Arts, H. Alexander, additional, Ashram, Yasmine A., additional, Aviv, Jonathan E., additional, Aygun, Nafi, additional, Backous, Douglas D., additional, Baker, Shan R., additional, Balkany, Thomas J., additional, Baloh, Robert W., additional, Barkmeier-Kraemer, Julie, additional, Baroody, Fuad M., additional, Bartlett, Nancy L., additional, Baskin, Jonathan Z., additional, Bastian, Robert W., additional, Bauer, Carol A., additional, Benninger, Michael S., additional, Bhama, Prabhat K., additional, Bhatti, Nasir Islam, additional, Blitzer, Andrew, additional, Boardman, Simone, additional, Boss, Emily F., additional, Brackmann, Derald E., additional, Bradford, Carol R., additional, Branstetter, Barton F., additional, Braun, Edward B., additional, Briggs, Robert J.S., additional, Brodie, Hilary A., additional, Brown, Carolyn J., additional, Brown, David J., additional, Brown, Kevin D., additional, Browne, J. Dale, additional, Buatti, John M., additional, Buchmann, Luke, additional, Byrne, Patrick J., additional, Galzada, Gabriel G., additional, Carey, John P., additional, Casselbrant, Margaretha L., additional, Castelnuovo, Paolo, additional, Chang, Steven, additional, Chegar, Burke E., additional, Chen, Amy, additional, Chen, Eunice Y., additional, Chen, Theodore, additional, Chepeha, Douglas B., additional, Cheuk, Alice, additional, Chheda, Neil N., additional, Chien, Wade, additional, Choi, Sukgi S., additional, Chole, Richard A., additional, Christian, James M., additional, Chu, Eugene A., additional, Citardi, Martin J., additional, Cohen, Marc A., additional, Collins, Savita, additional, Collop, Nancy A., additional, Contencin, Philippe, additional, Cook, Raymond, additional, Corey, Jacquelynne, additional, Cotton, Robin T., additional, Couch, Marion Everett, additional, Courey, Mark S., additional, Crane, Benjamin T., additional, Crumley, Roger L., additional, Cruz, Oswaldo Laércio M., additional, Culicchia, Frank, additional, Cummings, Charles W., additional, Cunningham, Calhoun D., additional, Davis, Greg E., additional, Davis, Larry E., additional, Day, Terry A., additional, De la Cruz, Antonio, additional, Santina, Charles C. Della, additional, Denlinger, Chadrick, additional, Derkay, Craig S., additional, Diaz, Rodney C., additional, Dobie, Robert A., additional, Galli, Suzanne K. Doud, additional, Duncan, Newton O., additional, Eggers, Scott D.Z., additional, Eisbruch, Avraham, additional, Eisele, David W., additional, El-Kashlan, Hussam K., additional, Elluru, Ravindhra G., additional, Ende, Kevin H., additional, Erman, Audrey B., additional, Fakhri, Samer, additional, Fakhry, Carole, additional, Farrior, Edward H., additional, Farrior, Richard T., additional, Faust, Russell A., additional, Ferguson, Berrylin J., additional, Flint, Paul W., additional, Francis, Howard W., additional, Fried, Marvin P., additional, Friedland, David R., additional, Friedman, Oren, additional, Frodel, John L., additional, Funk, Gerry F., additional, Gantz, Bruce J., additional, Garrett, C. Gaelyn, additional, Gartner-Schmidt, Jackie, additional, Gay, William Donald, additional, Ge, Norman N., additional, Gillespie, M. Boyd, additional, Girod, Douglas A., additional, Goding, George S., additional, Goldberg, Andrew N., additional, Goldenberg, David, additional, Graney, Daniel O., additional, Grant, Nazaneen N., additional, Grégoire, Vincent, additional, Gries, Heike, additional, Gubbels, Samuel P., additional, Guss, Joel, additional, Ha, Patrick, additional, Hamilton, Grant S., additional, Hanna, Ehab Y., additional, Harker, Lee A., additional, Harréus, Uli, additional, Harrison, Robert V., additional, Haughey, Bruce H., additional, Hellstein, John W., additional, Herzer, Kurt, additional, Hildebrand, Michael S., additional, Hilgers, Frans J.M., additional, Hill, Justin D., additional, Hinni, Michael L., additional, Hoffman, Henry T., additional, Holbrook, Eric H., additional, Holinger, Lauren D., additional, Holzapfel, Allison MacGregor, additional, Hom, David B., additional, House, John W., additional, House, Joyce Colton, additional, Hullar, Timothy E., additional, Husein, Murad, additional, Ing, Steven, additional, Iseli, Tim A., additional, Ishman, Stacey, additional, Jackler, Robert K., additional, Jameson, Brian, additional, Jenkins, Herman A., additional, Jin, Hong-Ryol, additional, Joe, John K., additional, Joe, Stephanie A., additional, Johnson, Gary, additional, Johnson, Rhonda, additional, Johnson, Tiffany A., additional, Johnson, Timothy M., additional, Jones, Nick S., additional, Kabaker, Sheldon S., additional, Karnell, Lucy H., additional, Kashima, Matthew L., additional, Kellman, Robert M., additional, Kelly, Paul E., additional, Kennedy, David W., additional, Khalid, Ayesha N., additional, Kies, Merrill S., additional, Kileny, Paul R., additional, Kim, David W., additional, Kim, Jason H., additional, Kim, Theresa B., additional, Kimberling, William J., additional, Koh, Jeffrey, additional, Kokot, Niels, additional, Koltai, Peter J., additional, Kozak, Frederick K., additional, Krakovitz, Paul R., additional, Kridel, Russell W.H., additional, Kumar, Parvesh, additional, Kunduk, Melda, additional, Laccourreye, Ollivier, additional, Lacey, JoAnne, additional, Lai, Stephen Y., additional, Lal, Devyani, additional, Lalwani, Anil K., additional, Lambert, Paul R., additional, Lassig, Amy Anne, additional, Latchaw, Richard E., additional, Leahy, Kevin P., additional, Lee, Daniel J., additional, Lee, Ken K., additional, Lee, Nancy, additional, Lefebvre, Jean-Louis, additional, Lefton-Greif, Maureen A., additional, Leopold, Donald A., additional, Lewis, James S., additional, Li, Daqing, additional, Lian, Timothy S., additional, Licameli, Greg R., additional, Limb, Charles J., additional, Logemann, Jeri A., additional, Loh, Thomas, additional, Lonsbury-Martin, Brenda L., additional, Lopez, Manuel A., additional, Lusk, Rodney P., additional, Lustig, Lawrence R., additional, Lysakowski, Anna, additional, MacArthur, Carol J., additional, Maisel, Robert H., additional, Malone, James P., additional, Mandel, Ellen M., additional, Mandel, Susan J., additional, Manning, Scott C., additional, Mark, Lynette, additional, Markt, Jeffery C., additional, Marsh, Michael, additional, Martin, Glen K., additional, Mattox, Douglas E., additional, McCaffrey, Thomas V., additional, McCulloch, Timothy M., additional, McGee, JoAnn, additional, McGuire, John F., additional, McJunkin, Jonathan, additional, McMurray, J. Scott, additional, Merati, Albert L., additional, Merchant, Saumil N., additional, Messner, Anna H., additional, Michelson, James, additional, Milczuk, Henry A., additional, Minor, Lloyd B., additional, Mobley, Steven Ross, additional, Muntz, Harlan, additional, Murakami, Craig S., additional, Myer, Charles M., additional, Naclerio, Robert M., additional, Nadol, Joseph B., additional, Nassif, Paul S., additional, Nedzelski, Julian, additional, Nicolai, Piero, additional, Nielsen, David R., additional, Niparko, John K., additional, Norton, Susan J., additional, Nouraei, S.A. Reza, additional, Nuss, Daniel W., additional, Nussenbaum, Brian, additional, Odland, Rick M., additional, O'Donoghue, Gerard, additional, Oliver, Eric R., additional, O’Malley, Bert W., additional, O’Reilly, Robert C., additional, Ospina, Juan Camilo, additional, Ossoff, Robert H., additional, Otto, Kristen J., additional, Packer, Mark D., additional, Pallanch, John, additional, Palmer, James N., additional, Park, Stephen S., additional, Patel, Sundip, additional, Patterson, G. Alexander, additional, Pearson, Bruce W., additional, Pellitteri, Phillip K., additional, Perkins, Jonathan A., additional, Perkins, Stephen W., additional, Pero, Colin D., additional, Pignatari, Shirley S.N., additional, Pletcher, Steven D., additional, Popovtzer, Aron, additional, Postma, Gregory N., additional, Potsic, William P., additional, Poznanovic, Sheri A., additional, Quatela, Vito C., additional, Rabinov, C. Rose, additional, Ramachandran, Virginia, additional, Randolph, Gregory W., additional, Rassekh, Christopher H., additional, Rauch, Steven D., additional, Reinisch, Lou, additional, Richardson, Mark, A., additional, Richter, Gresham T., additional, Ridgway, James M., additional, Robbins, K. Thomas, additional, Roediger, Frederick C., additional, Rogers, Jeremy, additional, Ronen, Ohad, additional, Rosenfeld, Richard M., additional, Rotter, Bruce E., additional, Rubinstein, Jay T., additional, Ruckenstein, Michael J., additional, Rumboldt, Zoran, additional, Runge-Samuelson, Christina L., additional, Rybak, Leonard P., additional, Sadoughi, Babak, additional, Salassa, John R., additional, Salinas, Thomas J., additional, Samant, Sandeep, additional, Samlan, Robin A., additional, Samy, Ravi N., additional, Sandel, Henry D., additional, Sandhu, Guri S., additional, Sando, Isamu, additional, Sauder, Cara, additional, Scarlett, Jeremy A., additional, Scher, Richard L., additional, Schessel, David A., additional, Schmalbach, Cecelia E., additional, Schwedt, Todd J., additional, Sciubba, James J., additional, Sequeira, Sunitha, additional, Seshamani, Meena, additional, Shelton, Clough, additional, Shepard, Neil T., additional, Ship, Jonathan A., additional, Shirley, W. Peyton, additional, Shnayder, Yelizaveta, additional, Shvidler, Joseph, additional, Sie, Kathleen C.Y., additional, Simmen, Daniel B., additional, Smith, Marshall E., additional, Smith, Richard J.H., additional, Sofferman, Robert A., additional, Soma, Marlene, additional, Stach, Brad A., additional, Staecker, Hinrich, additional, Stamm, Aldo Cassol, additional, Stankiewicz, James A., additional, Stavinoha, Rose, additional, Sterni, Laura M., additional, Steward, David L., additional, Stocks, Rose Mary S., additional, Sudhoff, Holger H., additional, Sunwoo, John B., additional, Swanson, Neil A., additional, Swanson, Veronica C., additional, Swarm, Robert A., additional, Sykes, Jonathan M., additional, Tan, Luke, additional, Tardy, M. Eugene, additional, Tatum, Sherard A., additional, Taylor, S. Mark, additional, Teissier, Natacha, additional, Telian, Steven A., additional, Terris, David J., additional, Teufert, Karen B., additional, Thomas, J. Regan, additional, Thompson, James N., additional, Toriumi, Dean M., additional, Torres, Alejandro I., additional, Travers, Joseph B., additional, Travers, Susan P., additional, Tsue, Terance T., additional, Tufano, Ralph P., additional, Tunkel, David E., additional, Turner, Michael D., additional, Uppaluri, Ravindra, additional, Vaezi, Michael F., additional, Van den Abbeele, Thierry, additional, van den Brekel, Michiel W.M., additional, Vaysberg, Mikhail, additional, Vokes, David E., additional, Wackym, P. Ashley, additional, Wakefield, Tamekia L., additional, Walner, David L., additional, Walsh, Edward J., additional, Walvekar, Rohan R., additional, Wang, Tom D., additional, Warren, Frank M., additional, Weber, Randal S., additional, Wein, Richard O., additional, Weinstein, Gregory S., additional, Weitzel, Erik Kent, additional, Welling, D. Bradley, additional, Wemer, Richard D., additional, Wetmore, Ralph F., additional, Weymuller, Ernest A., additional, Wiatrak, Brian J., additional, Wiet, Gregory J., additional, Wiggins, Richard H., additional, Willey, Andrea, additional, William, William N., additional, Williams, Glenn B., additional, Wippold, Franz J., additional, Woodson, Gayle Ellen, additional, Woolley, Audie L., additional, Wootten, Christopher T., additional, Wormald, Peter-John, additional, Yingling, Charles D., additional, Yueh, Bevan, additional, Yung, Rex C., additional, Zaldívar, Renzo A., additional, Zalzal, George H., additional, Zee, David S., additional, Zimbler, Marc S., additional, Zinreich, S. James, additional, and Zwolan, Teresa A., additional

Published
2010
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38. Systemic steroid for chronic otitis media with effusion in children

Author

Mandel, Ellen M., Casselbrant, Margaretha L., Rockette, Howard E., Fireman, Philip, Kurs-Lasky, Marcia, and Bluestone, Charles D.

Subjects
Otitis media with effusion -- Care and treatment, Amoxicillin -- Dosage and administration, Antibiotics -- Dosage and administration, Fluocinolone acetonide -- Dosage and administration
Abstract

Objective. To determine the efficacy of a short course of an adrenocorticosteroid agent (prednisolone) given with amoxicillin as compared with that of amoxicillin alone for the treatment of chronic middle ear effusion (MEE). The efficacy of 2 weeks versus 4 weeks of amoxicillin with and without steroid was also assessed. Methods. In a double-blind, randomized trial, children who were 1 to 9 years of age and had MEE of at least 2 months' duration were assigned to 1 of 4 treatment arms: 1) steroid + amoxicillin for 14 days, then amoxicillin for 14 more days; 2) steroid + amoxicillin for 14 days, then placebo for amoxicillin for 14 more days; 3) placebo (for steroid) + amoxicillin for 14 days, then amoxicillin for 14 more days; or 4) placebo (for steroid) + amoxicillin for 14 days, then placebo for amoxicillin for 14 more days. Children were examined by otoscopy, tympanometry, and audiometry at entry and 2 and 4 weeks after entry; those without MEE at the 4-week visit returned monthly for up to 3 more visits or until recurrence of effusion. Serum immunoglobulin (Ig) G, IgM, IgA, and varicella titers were obtained at entry, and allergy skin testing was performed at the 4-week visit. Results. A total of 144 children was entered; 135 children (94%) returned for the 2-week visit, and 132 (92%) were seen for the 4-week visit. At the 2-week visit, 33.3% of children in the steroid + amoxicillin group had no MEE compared with 16.7% in the placebo + amoxicillin group (95% confidence interval for the difference in proportions: 2.4%-31.0%). At the 4-week visit, the percentage of children with no MEE in the steroid-treated group was 32.8%, whereas that in the placebo group was 20.0% (95% confidence interval for the difference in proportions in the 2 groups: -2.0%-27.7%). Comparing change in middle ear status from the 2- to the 4-week visit, there were no significant differences in recurrence of MEE or additional clearance 6f MEE between those who were treated with amoxicillin for 2 weeks and those who were treated for 4 weeks. By the 4-month visit, 68.4% of children who were in the steroid group and had no MEE at the 4-week visit had recurrence of MEE as did 69.2% of such children in the placebo group. A total of 126 (87.5%) children underwent allergy skin testing. Of the 122 children who had a positive reaction to histamine, 51 (41.8%) had 1 or more positive reactions to the test allergens. There was no difference in response to treatment between those with positive allergy tests and those without. Conclusions. There was a significant difference in the proportion of children who were effusion-free immediately after 14 days of treatment with steroid and amoxicillin compared with those who were treated only with amoxicillin for 14 days. Within 2 weeks of finishing treatment, there was no longer any significant difference between the 2 groups regardless of whether amoxicillin was continued or not. Therefore, we conclude that treatment with the dose and type of steroid used in this study should not be universally recommended for treatment of chronic otitis media with effusion, and treatment with amoxicillin, if used, should not continue beyond 14 days. Pediatrics 2002;110:1071-1080; otitis media, steroid, amoxicillin, middle ear effusion, allergy., ABBREVIATIONS. OME, otitis media with effusion; CHP, Children's Hospital of Pittsburgh; MEE, middle ear effusion; AOM, acute otitis media; TW, tympanometric width; SRT, speech recognition threshold; Ig, immunoglobulin; PTA, pure [...]

Published
2002

42. A casualty of the immunization wars: the reemergence of measles: vaccination results in full protection for more than 95% of recipients, and yet people are still coming down with measles and its potentially devastating complications

Author

DiPaola, Francesca, Michael, Austin, and Mandel, Ellen D.

Subjects
United States. Centers for Disease Control and Prevention, Conjunctivitis -- Diagnosis -- Development and progression -- Casualties, Health care industry, World Health Organization, American Academy of Pediatrics
Abstract

Measles, also known as rubeola, is often considered a disease of the past. Declared by the CDC to be eliminated from the United States in 2000,' measles is making a [...]

Published
2012

43. The SNAP treatment approach for children with acute otitis media: AOM usually resolves spontaneously, and the SNAP approach takes advantage of that, helping children to avoid antibiotic side effects and combating antibiotic resistance

Author

Mancini, Kristina D. and Mandel, Ellen D.

Subjects
Pediatrics -- Health aspects, Ear -- Inflammation, Drug resistance in microorganisms -- Complications and side effects -- Diagnosis -- Health aspects, Prescription writing -- Health aspects, Infection -- Complications and side effects -- Diagnosis -- Health aspects, Otitis media -- Complications and side effects -- Diagnosis -- Health aspects, Pediatric pharmacology -- Health aspects, Health care industry, American Academy of Pediatrics
Abstract

A 3-year-old boy with right ear pain is brought to a pediatric practice by his concerned mother. She is worried about an infection and urges the PA to prescribe an [...]

Published
2012

45. Diabetes Self-management Education and Support in Adults with Type 2 Diabetes: A Consensus Report of the American Diabetes Association, the Association of Diabetes Care and Education Specialists, the Academy of Nutrition and Dietetics, the American Academy of Family Physicians, the American Academy of PAs, the American Association of Nurse Practitioners, and the American Pharmacists Association

Author

Powers, Margaret A., primary, Bardsley, Joan K., primary, Cypress, Marjorie, primary, Funnell, Martha M., primary, Harms, Dixie, primary, Hess-Fischl, Amy, primary, Hooks, Beulette, primary, Isaacs, Diana, primary, Mandel, Ellen D., primary, Maryniuk, Melinda D., primary, Norton, Anna, primary, Rinker, Joanne, primary, Siminerio, Linda M., primary, and Uelmen, Sacha, primary

Published
2020
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46. Otitis media

Author

Mandel, Ellen, primary, Casselbrant, Margaretha, additional, and Fireman, Philip, additional

Published
2007
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