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324 results on '"Mandalenakis, Zacharias"'

4. Frailty and Cognitive Function in Middle-Aged and Older Adults With Congenital Heart Disease

Author

Sasikumar, Navaneetha, Enomoto, Junko, Mizuno, Yoshiko, Leong, Ming Chern, Binto Sabran, Izzatun Nafsi, Ladak, Laila Akbar, Hasan, Babar, Siddiqui, Ayat, Moon, Ju Ryoung, Huh, June, Yang, Hsiao-Ling, Wang, Jou-Kou, Lu, Chun-Wei, Demir, Fatma, Öden, Tuğba, Tefera, Endale, Mwita, Julius, Ambassa, Jean-Claude, Mvondo, Charles, Fanka, Marcel, Yadeta, Dejuma, Alemayehu, Mulualem, Leye, Mohamed, Gueye, Khadija, Gabriel, Harald, Svhneider, Matthias, Seeliger, Selina, Budts, Werner, Van De Bruaene, Alexander, Moons, Philip, Goossens, Eva, Van Bulck, Liesbet, Rassart, Jessica, Luyckx, Koen, De Hosson, Michele, De Backer, Julie, Kaneva, Anna, Markova, Mila, Lykkeberg, Birgitte, Biyai, Miriam, Ladouceur, Magalie, Boubrit, Anissa, Thambo, Jean-Benoît, Ruissel, Amandine, Jore, Cecile, Amedro, Pascal, Abassi, Hamouda, Soltani, Sonia, Bredy, Charlene, Giannakoulas, George, Kosmidis, Diamantis, Ntiloudi, Despina, Callus, Edward, Pagliuca, Silvana, Bertoldo, Enrico Giuseppe, Fiolo, Valentina, Caruana, Maryanne, Swain, Justine, Grech, Neil, Xuereb, Rachel, Craus, Sarah, Bonello, Maria, Borg, Darren, Farrugia, Paul, Cardona, Joanne, Estensen, Mette-Elise, Andresen, Brith, Eriksen, Katrine, Areias, Maria Emília, Miranda, Joana, Areias, José Carlos, Cruz, Cristina, Macedo, Filipe, Ribeiro Nunes, Filipa Manuela, Barbosa de Bessa, Ana Maria, Espírito Santo, Sara Mafalda, Brito, Paula, Pereira, Marisa, Teixeira, Sofia, Marques, Brenda, Marques, Ana Raquel, Johansson, Bengt, Sandberg, Camilla, Cronesten, Helena, Dellborg, Mikael, Mandalenakis, Zacharias, Mattson, Eva, Christersson, Christina, Robertsson, Louise, Hlebowicz, Joanna, Ternrud, Linda, Thomet, Corina, Ruperti, Javier, Bouchardy, Judith, Brand, Fanny, Rutz, Tobias, Blanche, Coralie, van Melle, Joost P., Boer, Anna, Constantine, Andrew, Gatzoulis, Michael A., Dimopoulos, Konstantinos, Coats, Louise, McParlin, Debbie, Khairy, Paul, Proietti, Anna, Roy, Veronique, Windram, Jonathan, Jandura, Deborah, Jameson, Susan, Major, Melissa, Mahadevan, Vaikom Subremanian, Nguyen, Thomas, Sarwary, Shabir, Saidi, Arwa, Breault, Leah, Colon, Dalia Lopez, Cedars, Ari, Kutty, Shelby, Ko, Jong, Valente, Anne Marie, Brainard, Sarah, Reichman, Jeffrey, Zaidi, Ali, Amlani, Amrin, Jackson, Jamie, Swenski, Taylor, Neville, Steven, Kovacs, Adrienne, McGrath, Lidija, Taunton, Marshall, Kim, Yuli, Carducci, Jessica, Bashey, Saffy, Alday, Luis, Lousararian, Marina, Maisuls, Héctor, Quinteros, Marisa, Lucero, Mónica, Ortiz, Lucia, Amaral, Fernando, Schmidt, Andre, Manso, Paulo Henrique, Pavão, Rafael Brolio, Reyes, Fernando Baraona, Arancibia, M. Francisca, Araujo, John Jairo, Súarez, Alberto Hernadez, Menahem, Samuel, Wijayarathne, Pasangi Madhuka, Daelman, Bo, Kovacs, Adrienne H., Schmidt, André, and de Hosson, Michèle

Published
2024
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12. Phenotype clustering of hospitalized high-risk patients with COVID-19 — a machine learning approach within the multicentre, multinational PCHF-COVICAV registry

Author

Sokolski, Mateusz, primary, Trenson, Sander, additional, Reszka, Konrad, additional, Urban, Szymon, additional, Sokolska, Justyna M., additional, Biering-Sørensen, Tor, additional, Højbjerg Lassen, Mats C., additional, Skaarup, Kristoffer Grundtvig, additional, Basic, Carmen, additional, Mandalenakis, Zacharias, additional, Ablasser, Klemens, additional, Rainer, Peter P., additional, Wallner, Markus, additional, Rossi, Valentina A., additional, Lilliu, Marzia, additional, Loncar, Goran, additional, Cakmak, Huseyin A., additional, Ruschitzka, Frank, additional, and Flammer, Andreas J., additional

Published
2024
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14. Rationale, design and methodology of APPROACH-IS II: International study of patient-reported outcomes and frailty phenotyping in adults with congenital heart disease

Author

Van Bulck, Liesbet, Kovacs, Adrienne H., Goossens, Eva, Luyckx, Koen, Zaidi, Ali, Wang, Jou-Kou, Yadeta, Dejuma, Windram, Jonathan, Van De Bruaene, Alexander, Thomet, Corina, Thambo, Jean-Benoît, Taunton, Marshall, Sasikumar, Navaneetha, Sandberg, Camilla, Saidi, Arwa, Rutz, Tobias, Ortiz, Lucia, Mwita, Julius Chacha, Moon, Ju Ryoung, Menahem, Samuel, Mattsson, Eva, Mandalenakis, Zacharias, Mahadevan, Vaikom S., Lykkeberg, Birgitte, Leye, Mohamed, Leong, Ming Chern, Ladouceur, Magalie, Ladak, Laila Akbar, Kim, Yuli, Khairy, Paul, Kaneva, Anna, Johansson, Bengt, Jackson, Jamie L., Giannakoulas, George, Gabriel, Harald, Fernandes, Susan M., Enomoto, Junko, Demir, Fatma, de Hosson, Michèle, Constantine, Andrew, Coats, Louise, Christersson, Christina, Cedars, Ari, Caruana, Maryanne, Callus, Edward, Brainard, Sarah, Bouchardy, Judith, Boer, Anna, Baraona Reyes, Fernando, Areias, Maria Emília, Araujo, John Jairo, Andresen, Brith, Amedro, Pascal, Ambassa, Jean-Claude, Amaral, Fernando, Alday, Luis, and Moons, Philip

Published
2022
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18. Heart failure in patients with congenital heart disease after a cancer diagnosis.

Author

Karazisi, Christina, Dellborg, Mikael, Mellgren, Karin, Giang, Kok Wai, Skoglund, Kristofer, Eriksson, Peter, and Mandalenakis, Zacharias

Subjects
HEART failure patients, CARDIAC patients, CONGENITAL heart disease, CANCER patients, HEART failure
Abstract

Aims: Individuals with congenital heart disease (CHD) are at an increased risk for cancer. As cancer survival rates improve, the prevalence of late side effects, such as heart failure (HF), is becoming more evident. This study aims to evaluate the risk of developing HF following a cancer diagnosis in patients with CHD, compared with those without CHD and with CHD patients who do not have cancer. Methods: CHD patients (n = 69 799) and randomly selected non‐CHD controls (n = 650 406), born in Sweden between 1952 and 2017, were identified from the Swedish National Health Registers and Total Population Register (excluding those with syndromes and transplant recipients). CHD patients who developed cancer (n = 1309) were propensity score‐matched with non‐CHD patients who developed cancer (n = 9425), resulting in a cohort of 1232 CHD patients with cancer and 2602 non‐CHD controls with cancer (after exclusion of individuals with HF prior to cancer diagnosis). In a separate analysis, CHD patients with cancer were propensity score‐matched with CHD patients without cancer (n = 68 490). A total of 1233 CHD patients with cancer and 2257 CHD patients without cancer were included in the study. Results: Among CHD patients with cancer, 73 (5.9%) developed HF during a mean follow‐up time of 8.5 ± 8.7. Comparatively, in the propensity‐matched control population, 29 (1.1%) non‐CHD cancer patients (mean follow‐up time of 7.3 ± 7.5) and 101 (4.5%) CHD patients without cancer (mean follow‐up time of 9.9 ± 9.2) developed HF. CHD patients exhibited a significantly higher risk of HF post‐cancer diagnosis compared with the non‐CHD control group [hazard ratio (HR) 4.39, 95% confidence interval (CI) 2.83–6.81], after adjusting for age at cancer diagnosis and comorbidities. In the analysis between CHD patients with cancer and those without cancer, the results indicated a significantly higher risk of developing HF in CHD patients with cancer (HR 1.53, 95% CI 1.13–2.07). Conclusions: CHD patients face a more than four‐fold increased risk of developing HF after a cancer diagnosis compared with cancer patients without CHD. Among CHD patients, the risk of HF is only modestly higher for those with cancer than for those without cancer. This suggests that the increased HF risk in CHD patients with cancer, relative to non‐CHD cancer patients, may be more attributable to CHD itself than to cancer treatment‐related side effects. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Corrigendum to “Risk of cancer in young and older patients with congenital heart disease and the excess risk of cancer by syndromes, organ transplantation and cardiac surgery: Swedish health registry study (1930–2017)” [The Lancet Regional Health–Europe 18 (2022) 100407]

Author

Karazisi, Christina, primary, Dellborg, Mikael, additional, Mellgren, Karin, additional, Giang, Kok Wai, additional, Skoglund, Kristofer, additional, Eriksson, Peter, additional, and Mandalenakis, Zacharias, additional

Published
2024
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34. Risk Factors for and Risk of Peripheral Artery Disease in Swedish Individuals With Type 2 Diabetes: A Nationwide Register-Based Study.

Author

Avdic, Tarik, Carlsen, Hanne K., Isaksson, Rikard, Gudbjörnsdottir, Soffia, Mandalenakis, Zacharias, Franzén, Stefan, Sattar, Naveed, Beckman, Joshua A., McGuire, Darren K., and Eliasson, Björn

Abstract

OBJECTIVE: To investigate to what extent having control of peripheral artery disease (PAD) risk factors is associated with the risk of incident PAD in individuals with type 2 diabetes. RESEARCH DESIGN AND METHODS: A total of 148,096 individuals with type 2 diabetes in the Swedish National Diabetes Register between 2005 and 2009 were included and matched with 320,066 control subjects on the basis of age, sex, and county. A few control subjects who developed type 2 diabetes after recruitment, during wash-in (<0.2%), were not censored but instead matched with two new control subjects. Individuals with type 2 diabetes were evaluated according to the number of PAD risk factors beyond recommended guideline levels at baseline, including LDL cholesterol, blood pressure, smoking, glycated hemoglobin, and estimated glomerular filtration rate. Incident PAD events were ascertained from 2006 to 2019. RESULTS: A graded association was observed between the number of PAD risk factors not at target and incident PAD in individuals with type 2 diabetes. The adjusted hazard ratio for PAD was 1.41 (95% CI 1.23–1.63) for those with type 2 diabetes with all PAD risk factors within target compared with control subjects matched for sex, age, and county but not risk factor status, in contrast with 9.28 (95% CI 3.62–23.79) for those with all five PAD risk factors not at target. CONCLUSIONS: A graded association was observed between increasing number of PAD risk factors not at target and incident PAD in individuals with type 2 diabetes. [ABSTRACT FROM AUTHOR]

Published
2024
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50. Cardiorenal Function and Survival in In-Hospital Cardiac Arrest: A Nationwide Study of 22,819 Cases

Author

Berglund, Sara, primary, Andreasson, Axel, additional, Rawshani, Aidin, additional, Hirlekar, Geir, additional, Lundgren, Peter, additional, Angerås, Oscar, additional, Mandalenakis, Zacharias, additional, Redfors, Björn, additional, Holm, Astrid, additional, Hagberg, Eva, additional, Ricksten, Sven-Erik, additional, Friberg, Hans, additional, Gustafsson, Linnea, additional, Dworeck, Christian, additional, Herlitz, Johan, additional, and Rawshani, Araz, additional

Published
2022
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