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3. Recommendations for reporting outcome results in abdominal wall repair: Results of a Consensus meeting in Palermo, Italy, 28–30 June 2012

Author

Muysoms, F. E., Deerenberg, E. B., Peeters, E., Agresta, F., Berrevoet, F., Campanelli, G., Ceelen, W., Champault, G. G., Corcione, F., Cuccurullo, D., DeBeaux, A. C., Dietz, U. A., Fitzgibbons, Jr, R. J., Gillion, J. F., Hilgers, R.-D., Jeekel, J., Kyle-Leinhase, I., Köckerling, F., Mandala, V., Montgomery, A., Morales-Conde, S., Simmermacher, R. K. J., Schumpelick, V., Śmietański, M., Walgenbach, M., and Miserez, M.

Published
2013
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6. Clinical strategies for the management of intestinal obstruction and pseudo-obstruction. A Delphi Consensus study of SICUT (Società Italiana di Chirurgia d'Urgenza e del Trauma)

Author

Costa, G., Ruscelli, P., Balducci, G., Buccoliero, F., Lorenzon, L., Frezza, B., Chirletti, P., Stagnitti, F., Miniello, S., Stella, F., Agresta, F., Ansaloni, L., Basile, G., Bellanova, G., Blandamura, V., Buonanno, G., Calderale, S., Caronna, R., Casciaro, G., Catena, F., Ceci, F., Chiara, O., Chiarugi, M., Cimbanassi, S., Coccolini, F., Gianfranco Cocorullo, Manzoni, G., Di Grezia, G., Frego, M., Fusco, B., Giulini, S., Greco, M., Gaspare Gulotta, Lippolis, P., Mandala, V., Marini, P., Martino, A., Marzaioli, R., Mecarelli, V., Mingoli, A., Mirabella, A., Morelli, M., Padalino, P., Picardi, N., Portolani, N., Ribaldi, S., Ricci, G., Salamone, Giuseppe, Sartelli, M., Staudacher, C., Tonelli, P., Tricarico, F., Trojaniello, B., Tugnoli, G., Valeri, A., Venezia, P., Zago, M., Costa, G., Ruscelli, P., Balducci, G., Buccoliero, F., Lorenzon, L., Frezza, B., Chirletti, P., Stagnitti, F., Miniello, S., Stella, F., Agresta, F., Ansaloni, L., Basile, G., Bellanova, G., Blandamura, V., Buonanno, G., Calderale, S., Caronna, R., Casciaro, G., Catena, F., Ceci, F., Chiara, O., Chiarugi, M., Cimbanassi, S., Coccolini, F., Cocorullo, G., De Manzoni, G., Di Grezia, G., Frego, M., Fusco, B., Giulini, S., Greco, M., Gulotta, G., Lippolis, P., Mandala, V., Marini, P., Martino, A., Marzaioli, R., Mecarelli, V., Mingoli, A., Mirabella, A., Morelli, M., Padalino, P., Picardi, N., Portolani, N., Ribaldi, S., Ricci, G., Salamone, G., Sartelli, M., Staudacher, C., Tonelli, P., Tricarico, F., Trojaniello, B., Tugnoli, G., Valeri, A., Venezia, P., and Zago, M.

Subjects
Hernia, Delphi Technique, Contrast Media, Acidosis, Conservative Treatment, Diatrizoate Meglumine, Disease Management, Emergencies, Emergency Medicine, General Surgery, Humans, Intestinal Obstruction, Intestinal Pseudo-Obstruction, Intubation, Gastrointestinal, Laparotomy, Societies, Medical, Stents, Symptom Assessment, Tomography, X-Ray Computed, Stent, Large bowel obstruction, Emergencie, Small bowel, Delphi study, Intestinal obstruction, Large bowel obstruction, Pseudo-obstruction, Small bowel, Delphi study, Acidosi, Pseudo-obstruction, Human
Abstract

Intestinal obstructions/pseudo-obstruction of the small/large bowel are frequent conditions but their management could be challenging. Moreover, a general agreement in this field is currently lacking, thus SICUT Society designed a consensus study aimed to define their optimal workout.The Delphi methodology was used to reach consensus among 47 Italian surgical experts in two study rounds. Consensus was defined as an agreement of 75.0% or greater. Four main topic areas included nosology, diagnosis, management and treatment.A bowel obstruction was defined as an obstacle to the progression of intestinal contents and fluids generally beginning with a sudden onset. The panel identified four major criteria of diagnosis including absence of flatus, presence of3.5 cm ileal levels or6 cm colon dilatation and abdominal distension. Panel also recommended a surgical admission, a multidisciplinary approach, and a gastrografin swallow for patients presenting occlusions. Criteria for immediate surgery included: presence of strangulated hernia, a10 cm cecal dilatation, signs of vascular pedicles obstructions and persistence of metabolic acidosis. Moreover, rules for non-operative management (to be conducted for maximum 72 hours) included a naso-gastric drainage placement and clinical and laboratory controls each 12 hours. Non-operative treatment should be suspended if any suspects of intra-abdominal complications, high level of lactates, leukocytosis (18.000/mm3 or Neutrophils85%) or a doubling of creatinine level comparing admission. Conversely, consensus was not reached regarding the exact timing of CT scan and the appropriateness of colonic stenting.This consensus is in line with current international strategies and guidelines, and it could be a useful tool in the safe basic daily management of these common and peculiar diseases.Delphi study, Intestinal obstruction, Large bowel obstruction, Pseudo-obstruction, Small bowel.Le ostruzioni e pseudo-ostruzioni del piccolo/ grande intestino sono condizioni frequenti, ma la loro gestione risulta spesso difficile per cui è necessario avere un adeguato e condiviso percorso gestionale. A tal proposito la Società Italiana di Chirurgia d’Urgenza e del Trauma (SICUT) ha disegnato uno studio volto a definire il management ottimale dei pazienti con occlusione intestinale.Lo studio è stato condotto utilizzando la metodologia Delphi coinvolgendo un panel di 47 chirurghi italiani con maturata esperienza clinica. Il consenso è stato definito come un accordo uguale o superiore al 75.0%. Lo studio si è focalizzato su quattro aree tematiche comprendenti la nosologia, la diagnosi, la gestione e il trattamento delle ostruzioni e delle pseudo-ostruzioni intestinali. Un occlusione intestinale è stata definita come un ostacolo alla progressione del contenuto intestinale. RISULTATI: in genere ad esordio improvviso. Il panel ha identificato quattro principali criteri di diagnosi, tra i quali l’assenza di canalizzazione ai gas, la presenza di livelli ileali3.5 cm o di una dilatazione del colon6 cm nonché di una distensione addominale. Viene inoltre consigliato il ricovero in chirurgia, un approccio multidisciplinare e un transito con Gastrografin per tutti i pazienti che presentano un’occlusione. Tra i criteri per un intervento chirurgico immediato sono inclusi: la presenza di un’ernia strozzata, una dilatazione del cieco10 cm, segni di ostruzione del peduncolo vascolare e la persistenza di acidosi metabolica. La gestione non operatoria dei pazienti (la cui durata massima dovrebbe essere di 72 ore) include il posizionamento di un sondino nasogastrico e la necessità di effettuare controlli clinici e laboratoristici ogni 12 ore. Il trattamento non operatorio deve essere sospeso in caso insorga il sospetto di complicanze intra-addominali, compaia un alto livello di lattati, una leucocitosi (18.000 / mm3 o neutrofili85%) o un raddoppiamento del livello di creatinina rispetto ai valori basali al ricovero. Al contrario il panel non ha raggiunto alcun consenso riguardo l’esatta tempistica della TAC e l’opportunità di stenting del colon come intervento palliativo in attesa di chirurgia definitiva.Le raccomandazioni stabilite sono in linea con le strategie e le linee guida internazionali, e potrebbero essere uno strumento utile per la gestione del paziente affetto da occlusione intestinale.

Published
2016

7. European Hernia Society guidelines on prevention and treatment of parastomal hernias

Author

Antoniou, S A, Agresta, F, Alamino, JMG, Berger, D, Berrevoet, F, Brandsma, HT, Bury, K, Conze, J, Cuccurullo, D, Dietz, UA, Fortelny, R H, Frei-Lanter, C, Hansson, B, Helgstrand, F, Hotouras, A, Janes, A, Kroese, Leonard, Lambrecht, JR, Kyle-Leinhase, I, Lopez-Cano, M, Maggiori, L, Mandala, V, Miserez, M, Montgomery, A, Morales-Conde, S, Prudhomme, M, Rautio, T, Smart, N, Smietanski, M, Szczepkowski, M, Stabilini, C, Muysoms, FE, Antoniou, S A, Agresta, F, Alamino, JMG, Berger, D, Berrevoet, F, Brandsma, HT, Bury, K, Conze, J, Cuccurullo, D, Dietz, UA, Fortelny, R H, Frei-Lanter, C, Hansson, B, Helgstrand, F, Hotouras, A, Janes, A, Kroese, Leonard, Lambrecht, JR, Kyle-Leinhase, I, Lopez-Cano, M, Maggiori, L, Mandala, V, Miserez, M, Montgomery, A, Morales-Conde, S, Prudhomme, M, Rautio, T, Smart, N, Smietanski, M, Szczepkowski, M, Stabilini, C, and Muysoms, FE

Published
2018

10. Regular Wine Consumption in Chronic Heart Failure: Impact on Outcomes, Quality of Life, and Circulating Biomarkers

Author

Cosmi, Franco, Di Giulio, Paola, Masson, Serge, Finzi, Andrea, Marfisi, Rosa Maria, Cosmi, Deborah, Scarano, Marco, Tognoni, Gianni, Maggioni, Aldo P., Porcu, Maurizio, Boni, Silvana, Cutrupi, Giovanni, Tavazzi, Luigi, Latini, Roberto Tavazzi, L, Tognoni, G, Barlera, S, Franzosi, Mg, Latini, R, Lucci, D, Maggioni, Ap, Marchioli, R, Nicolosi, Gl, Porcu, M, Yusuf, S, Camerini, F, Cohn, Jn, Decarli, A, Pitt, B, Sleight, P, Poole-Wilson, Pa, Geraci, E, Scherillo, M, Fabbri, G, Bartolomei, B, Bertoli, D, Cobelli, F, Fresco, C, Ledda, A, Levantesi, G, Opasich, C, Rusconi, F, Sinagra, G, Turazza, F, Volpi, A, Ceseri, M, Alongi, G, Atzori, A, Bambi, F, Bastarolo, D, Bianchini, F, Cangioli, I, Canu, V, Caporusso, C, Cenni, G, Cintelli, L, Cocchio, M, Confente, A, Fenicia, E, Friso, G, Gianfriddo, M, Grilli, G, Lazzaro, B, Lonardo, G, Luise, A, Nota, R, Orlando, M, Petrolo, R, Pierattini, C, Pierota, V, Provenzani, A, Quartuccio, V, Ragno, A, Serio, C, Spolaor, A, Tafi, A, Tellaroli, E, Ghio, S, Ghizzardi, E, Masson, S, Crociati, L, Rovere, Mt, Corra, U, Di Giulio, P, Finzi, A, Gorini, M, Gonzini, L, Milani, V, Orsini, G, Bianchini, E, Cabiddu, S, Cipressa, L, Cipressa, Ml, Di Bitetto, G, Ferri, B, Galbiati, L, Lorimer, A, Pera, C, Priami, P, Rossi, Mg, Pasotti, E, Vaghi, F, Roncarolo, P, Zunino, Mt, Matta, F, Actis, E, Gaita, F, Azzaro, G, Zanetta, M, Paino, Am, Parravicini, U, Vegis, D, Conte, R, Ferraro, P, De Bernardi, A, Morelloni, S, Fagnani, M, Lucchina, Pg, Montagna, L, Bellone, E, Sappe, D, Ferraro, F, Delucchi, M, Reynaud, Sg, Dore, M, La, A, Massobrio, N, Bo, L, Trinchero, R, Imazio, M, Brocchi, G, Nejrotti, A, Rissone, L, Gabasio, S, Zocchi, C, Randazzo, S, Crenna, A, Giannuzzi, P, Bonanomi, E, Mezzani, A, De Marchi, M, Begliuomini, G, Gianonatti, Ca, Gavazzi, A, Grosu, A, Cas, Ld, Nodari, S, Garyfallidis, P, Bertoletti, A, Bonifazi, C, Arisi, S, Mascaro, F, Fraccarollo, M, Dell, S, Sfolcini, M, Bortolini, F, Raccagni, D, Turelli, A, Santarone, M, Miglierina, E, Sormani, L, Jemoli, R, Tettamanti, F, Pirelli, S, Bianchi, C, Verde, S, Mariani, M, Ziacchi, V, Ferrazza, A, Russo, A, Bortolotti, M, Pasini, Gf, Jones, Kn, Cuzzucrea, D, Gullace, G, Carbone, C, Granata, A, De, S, Del Rosso, G, Inserra, C, Renaldini, E, Zappa, C, Moretti, M, Zanini, R, Ferrari, M, Cei, A, Lissi, C, Dovico, E, Fiorentini, C, Palermo, P, Brusoni, B, Negrini, M, Heyman, J, Danzi, Gb, Frigerio, M, Beretta, L, Sachero, A, Casazza, F, Squadroni, L, Lombardi, F, Marano, L, Margonato, A, Fragasso, G, Febo, Oc, Aiolfi, E, Olmetti, F, Grieco, A, Antonazzo, V, Specchia, G, Mortara, A, Robustelli, F, Songini, Mg, Schweiger, C, Frisinghelli, A, Palvarini, M, Campana, C, Scelsi, L, Marsan, Na, Gualco, A, De Feo, S, Iannone, Ma, Diaco, T, Zaniboni, D, Milanesi, G, Nassiacos, D, Meloni, S, Giani, P, Nicoli, T, Malinverni, C, Gusmini, A, Pozzoni, L, Bisiani, G, Margaroli, P, Schizzarotto, A, Daverio, A, Morelli, E, Occhi, G, Partesana, N, Bandini, P, Rosella, Mg, Giustiniani, S, Cucchi, G, Pedretti, R, Raimondo, R, Vaninetti, R, Fedele, A, Ghezzi, I, Rezzonico, E, Salerno, Ja, Morandi, F, Salvucci, F, Valenti, C, Graziano, G, Romano, M, Cimminiello, C, Mangone, I, Lombardo, M, Quorso, P, Marinoni, G, Breghi, M, Erckert, M, Dienstl, A, Mirante, G, Stefenelli, C, Cioffi, G, Buczkowska, E, Bonanome, A, Bazzanini, F, Parissenti, L, Serafini, C, Catania, G, Tarantini, L, Rigatelli, G, Boni, S, Pasini, A, Masini, E, Zampiero, Aa, Zanchetta, M, Franceschetto, L, Delise, P, Marcon, C, Sacchetta, A, Borgese, L, Artusi, L, Casolino, P, Corbara, F, Banzato, A, Barbiero, M, Aldegheri, Mp, Bazzucco, R, Crivellenti, G, Raviele, A, Zanella, C, Pascotto, P, Sarto, P, Milan, S, Barbieri, E, Girardi, P, Dalla, W, Mule, Jd, Di Sipio ML, Cazzin, R, Milan, D, Zonzin, P, Carraro, M, Rossi, R, Carbonieri, E, Rossi, I, Stritoni, P, Meneghetti, P, Risica, G, Tenderini, Pl, Vassanelli, C, Zanolla, L, Perini, G, Brighetti, G, Chiozza, R, Giuliano, G, Baldin, Mg, Gortan, R, Cesanelli, R, Piazza, R, Mos, L, Vriz, O, Pavan, D, Pascottini, G, Alberti, E, Werren, M, Solinas, L, Longaro, F, Fioretti, P, Albanese, Mc, Miani, D, Gianrossi, R, Pende, A, Rubartelli, P, Magaia, O, Caruso, D, Faraguti, As, Magliani, L, Miccoli, F, Guglielmino, G, Cantarelli, A, Orlandi, S, Vallebona, A, Pozzati, A, Brega, G, Pancaldi, Lg, Vandelli, R, Urbinati, S, Poci, Mg, Zoli, M, Costa, Gm, Guiducci, U, Zobbi, G, Tartagni, F, Tisselli, A, Gentili, A, Pieri, P, Cagnetta, E, Bendinelli, S, Barbieri, A, Conti, R, Ferrari, R, Merlini, F, Fucili, A, Moruzzi, P, Buia, E, Galvani, M, Ferrini, D, Baggioni, G, Yiannacopulu, P, Canè, G, Bonfiglioli, A, Zandomeneghi, R, Brugioni, L, Giannini, A, Di, R, Giuliani, M, Rusconi, L, Del Corso, P, Piovaccari, G, Bologna, F, Venturi, P, Melandri, F, Bagni, E, Bolognese, L, Perticucci, R, Zuppiroli, A, Nannini, M, Consoli, N, Petrone, P, Pipitò, C, Colombi, L, Bernardi, D, Mariani, Pr, Testa, R, Mazzinghi, F, Cosmi, F, Cosmi, D, Zipoli, A, Cecchi, A, Castelli, G, Ciaccheri, M, Mori, F, Pieri, F, Valoti, P, Chiarantini, D, Santoro, Gm, Minneci, C, Marchi, F, Milli, M, Zambaldi, G, Geri, Aa, Cipriani, M, Alessandri, M, Severi, S, Stefanelli, S, Comella, A, Poddighe, R, Digiorgio, A, Carluccio, M, Berti, S, Rizza, A, Bonatti, V, Molendi, V, Brancato, A, D'Aprile, N, Giappichini, G, Del Vecchio, S, Mantini, G, De Tommasi, F, Meucci, G, Cordoni, M, Bechi, S, Barsotti, L, Baldini, P, Romei, M, Scopelliti, G, Lauri, G, Pestelli, F, Furiozzi, F, Cocchieri, M, Severini, D, Patriarchi, F, Chiocchi, P, Buccolieri, M, Martinelli, S, Wee, A, Angelici, F, Bernardinangeli, M, Proietti, G, Biscottini, B, Panciarola, R, Marinacci, L, Perna, Gp, Gabrielli, D, Moraca, A, Moretti, L, Partemi, L, Gregori, G, Amici, R, Patteri, G, Capone, P, Savini, E, Morgagni, Gl, Paccaloni, L, Pezzuoli, F, Carincola, S, Papi, S, De Crescentini, S, Gerardi, P, Midi, P, Gallenzi, E, Pajes, G, Mancone, C, Di, V, Di Gennaro, M, Calcagno, S, Toscano, S, Antonicoli, S, Carta, F, Giorgi, G, Comito, F, Daniele, E, Goretti, Sm, Ciarla, O, Gelfo, Pg, Acquaviva, A, Testa, D, Testa, G, Pagliaro, Fa, Russo, F, Vetta, F, Marchese, I, Di, G, D'Ambrosio, A, Leggio, F, Del Sindaco, D, Lacchè, A, Avallone, A, Risa, Mp, Azzolini, P, Baldo, E, Giovannini, E, Pulignano, G, Tondo, C, Picchio, E, Biffani, E, Tanzi, P, Pozzar, F, Farnetti, F, Azzarito, M, Santini, M, Varveri, A, Ferraiuolo, G, Valtorta, C, Gaspardone, A, Barbato, G, Ceci, V, Aspromonte, N, Bellocci, F, Colizzi, C, Fedele, F, Perez, Fi, Galati, A, Rossetti, A, Mainella, A, Ciuffetta, D, Matteucci, C, Busi, G, De, A, Farina, G, Granatelli, A, Leone, F, Frasca, F, Castellani, G, Massaro, G, Mastrogiuseppe, G, Vacri, A, De Sanctis, F, Cioli, M, Di Luzio, S, Napoletano, C, Piccioni, Ll, De Simone, G, Ottaviano, A, Mazza, V, Spedaliere, C, Staniscia, Td, Calgione, E, De Marco, G, Chiacchio, T, Di, T, Romanzi, S, Salvatore, G, Golino, P, Palermo, A, Mascia, F, Vetrano, A, Vinciguerra, A, Caliendo, L, Longobardi, R, De Caro, G, Di Nola, R, Piemonte, F, Prinzi, D, De Rosa, P, De, V, Riello, F, Capuano, V, Vecchio, G, Landi, M, Amato, S, Garofalo, M, D'Avino, M, Sensale, P, Maiolica, O, Santoro, R, Caso, P, Miceli, D, Maurea, N, Bianchi, U, Crispo, C, Chiariello, M, Filardi, Pp, Russo, L, Capuano, N, Ungaro, G, Vergara, G, Scafuro, F, D'Angelo, G, Campaniello, C, Bottiglieri, P, Volpe, A, Battista, R, De Risi, L, Cardillo, G, Sibilio, G, Marino, Ap, Silvestri, F, Predotti, P, Iervoglini, A, De Matteis, C, Sarnicola, P, Matarazzo, Mm, Baldi, S, Iuliano, V, Astarita, C, Cuccaro, P, Liguori, A, Liguori, G, Gregorio, G, Petraglia, L, Antonelli, G, Amodio, G, De Luca, I, Franchini, G, Lenti, Ml, Cavallari, D, D'Agostino, C, Scalera, G, Altamura, Cm, Russo, M, Mascolo, Ar, Pettinati, G, Ciricugno, Sa, Scrutinio, D, Passantino, A, Mastrangelo, D, Di Masi, A, De, R, Cannone, M, Dibiase, F, Pensato, M, Loliva, F, Trapani, F, Panettieri, I, Leone, L, Di, M, Carrone, M, Gallone, V, Cocco, F, Costantini, M, Tritto, C, Cavalieri, F, Stella, L, Magliari, F, Callerame, M, De Giorgi, A, Pellegrino, L, Correra, M, Portulano, V, Nisi, Gl, Grassi, G, Cristallo, E, De Laura, D, Salerno, C, Fanelli, R, Villella, M, Pede, S, Renna, A, De Lorenzi, E, Urso, L, Lenti, V, Peluso, A, Baldi, N, Polimeni, G, Palma, P, Lauletta, R, Tagliamonte, E, Cirillo, T, Centonze, G, D'Alessandro, B, Truncellito, L, Mecca, D, Petruzzi, Ma, Coviello, Ro, Lopizzo, A, Chiaffitelli, M, Barbuzzi, S, Gubelli, S, Germinario, G, Cosentino, N, Mingrone, A, Vico, R, Borrello, G, Mazza, Ml, Cimino, R, Galasso, D, Cassadonte, F, Talarico, U, Perticone, F, Cassano, S, Catapano, F, Calemme, S, Feraco, E, Cloro, C, Misuraca, G, Caporale, R, Vigna, L, Spagnuolo, V, De Rosa, F, Spadafora, G, Zampaglione, G, Russo, R, Schipani, Fa, Ferragina, Af, Stranieri, D, Musca, G, Carpino, C, Bencardino, P, Raimondo, F, Musacchio, D, Pulitano, G, Ruggeri, A, Provenzano, A, Salituri, S, Musolino, M, Calandruccio, S, Marrari, A, Tripodi, E, Scali, R, Anastasio, L, Arone, A, Aragona, P, Donnangelo, L, Comito, Mg, Bilotta, F, Vaccaro, I, Rametta, R, Ventura, V, Bonvegna, A, Alì, A, Cinnirella, C, Raineri, M, Pompeo, F, Ingurgio, Nc, Carini, V, Coco, R, Giunta, G, Leonardi, G, Randazzo, V, Di Blasi, V, Tamburino, C, Russo, G, Mangiameli, S, Cardillo, R, Castelli, D, Inserra, V, Arena, A, Gulizia, Mm, Raciti, S, Rapisarda, G, Romano, R, Prestifilippo, P, Braschi, Gb, Ledda, G, Terrazzino, R, De Caro, M, Scilabra, G, Graffagnino, B, Grassi, R, Scimone, Gf, Vasquez, L, Coppolino, C, Casale, A, Castelli, M, D'Urso, G, D'Antonio, E, Presti, Ll, Badalamenti, E, Conti, P, Sanfilippo, N, Cirrincione, V, Cinà, Mt, Cusimano, G, Taormina, A, Giuliano, P, Bajardi, A, Mandala, V, Canonico, A, Geraci, G, Sabella, Fp, Enia, F, Floresta, Am, Cascio, Il, Gumina, D, Cavallaro, A, Piccione, G, Ferrante, R, Blandino, M, Iudicello, Ms, Mossuti, E, Romano, G, Lombardo, L, Monastra, P, Di Vincenzo, D, Orru, P, Muscas, F, Giardina, G, Corda, M, Locci, G, Podda, A, Ledda, M, Siddi, P, Lai, C, Pili, G, Mercuro, G, Mureddu, G, Ganau, A, Meloni, G, Poddighe, G, Sanna, G., Cosmi, Franco, Di Giulio, Paola, Masson, Serge, Finzi, Andrea, Marfisi, Rosa Maria, Cosmi, Deborah, Scarano, Marco, Tognoni, Gianni, Maggioni, Aldo P, Porcu, Maurizio, Boni, Silvana, Cutrupi, Giovanni, Tavazzi, Luigi, Latini, Roberto, on behalf of the GISSI-HF, Investigator, Margonato, Alberto, DI GIULIO, Paola, Maggioni, Aldo P., GISSI HF, Investigator, and Sinagra, Gianfranco

Subjects
Male, Health Status, Left, Wine, Comorbidity, Ventricular Function, Left, Health Statu, Quality of life, Risk Factors, Surveys and Questionnaires, Prevalence, Ventricular Function, Surveys and Questionnaire, Depression (differential diagnoses), Depression, Medicine (all), Middle Aged, Prognosis, biological marker, Italy, Female, Risk assessment, Cardiology and Cardiovascular Medicine, biological markers, Human, Cardiac function curve, Vasculitis, medicine.medical_specialty, Vasculiti, Alcohol Drinking, Prognosi, Lower risk, Risk Assessment, Internal medicine, medicine, Humans, Protective Factor, Aged, Heart Failure, business.industry, Risk Factor, Stroke Volume, Biomarker, quality of life, wine, aged, alcohol drinking, biomarkers, chronic disease, comorbidity, depression, female, heart failure, humans, italy, male, middle aged, prevalence, prognosis, protective factors, risk assessment, risk factors, stroke volume, surveys and questionnaires, vasculitis, ventricular function, left, health status, cardiology and cardiovascular medicine, Biomarkers, Chronic Disease, Protective Factors, Quality of Life, medicine.disease, Clinical trial, Heart failure, Physical therapy, business
Abstract

Background— Moderate, regular alcohol consumption is generally associated with a lower risk of cardiovascular events but data in patients with chronic heart failure are scarce. We evaluated the relations between wine consumption, health status, circulating biomarkers, and clinical outcomes in a large Italian population of patients with chronic heart failure enrolled in a multicenter clinical trial. Methods and Results— A brief questionnaire on dietary habits was administered at baseline to 6973 patients enrolled in the Gruppo Italiano per lo Studio della Sopravvivenza nell’Insufficienza Cardiaca-Heart Failure (GISSI-HF) trial. The relations between wine consumption, fatal and nonfatal clinical end points, quality of life, symptoms of depression, and circulating biomarkers of cardiac function and inflammation (in subsets of patients) were evaluated with simple and multivariable-adjusted statistical models. Almost 56% of the patients reported drinking at least 1 glass of wine per day. After adjustment, clinical outcomes were not significantly different in the predefined 4 groups of wine consumption. However, patients with more frequent wine consumption had a significantly better perception of health status (Kansas City Cardiomyopathy Questionnaire score, adjusted P P =0.01), and lower plasma levels of biomarkers of vascular inflammation (osteoprotegerin and C-terminal proendothelin-1, adjusted P P =0.01) after adjusting for possible confounders. Conclusions— We show for the first time in a large cohort of patients with chronic heart failure that moderate wine consumption is associated with a better perceived and objective health status, lower prevalence of depression, and less vascular inflammation, but does not translate into more favorable clinical 4-year outcomes. Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique identifier: NCT0033633.

Published
2015

12. WSES guidelines for emergency repair of complicated abdominal wall hernias

Author

Sartelli, M. (Massimo), Coccolini, F. (Federico), Ramshorst, G.H. (Gabrielle) van, Campanelli, G. (Giampiero), Mandala, V., Ansaloni, L. (Luca), Moore, E.E. (Ernest), Peitzman, A. (Andrew), Velmahos, G.C. (George ), Moore, F.A. (Fredrick), Leppaniemi, A. (Ari), Burlew, C.C. (Clay), Biffl, W.L. (Walter), Koike, K. (Kaoru), Kluger, Y. (Yoram), Fraga, G.P. (Gustavo), Ordonez, C.A. (Carlos), Di Saverio, S. (Salomone), Agresta, F., Sakakushev, B. (Boris), Gerych, I. (Igor), Wani, I. (Imtiaz), Kelly, M.D. (Michael ), Gomes, C.A. (Carlos), Faro Jr., M.P. (Mario), Taviloglu, K. (Korhan), Demetrashvili, Z. (Zaza), Lee, J.G. (Jeong ), Vettoretto, N. (Nereo), Guercioni, G. (Gianluca), Tranà, C. (Cristian), Cui, Y. (Yijun), Kok, K.Y.Y. (Kenneth), Ghnnam, W.M. (Wagih), Abbas, A.E.S. (Ashraf El-Sayed), Sato, N. (Norio), Marwah, S. (Sanjay), Rangarajan, M. (Muthukumaran), Ben-Ishay, O. (Offir), Adesunkanmi, A.R.K. (Abdul Rashid), Segovia Lohse, H.A. (Helmut), Kenig, J. (Jakub), Mandalà, V. (Vincenzo), Patrizi, A. (Andrea), Scibé, R. (Rodolfo), Catena, F. (Fausto), Sartelli, M. (Massimo), Coccolini, F. (Federico), Ramshorst, G.H. (Gabrielle) van, Campanelli, G. (Giampiero), Mandala, V., Ansaloni, L. (Luca), Moore, E.E. (Ernest), Peitzman, A. (Andrew), Velmahos, G.C. (George ), Moore, F.A. (Fredrick), Leppaniemi, A. (Ari), Burlew, C.C. (Clay), Biffl, W.L. (Walter), Koike, K. (Kaoru), Kluger, Y. (Yoram), Fraga, G.P. (Gustavo), Ordonez, C.A. (Carlos), Di Saverio, S. (Salomone), Agresta, F., Sakakushev, B. (Boris), Gerych, I. (Igor), Wani, I. (Imtiaz), Kelly, M.D. (Michael ), Gomes, C.A. (Carlos), Faro Jr., M.P. (Mario), Taviloglu, K. (Korhan), Demetrashvili, Z. (Zaza), Lee, J.G. (Jeong ), Vettoretto, N. (Nereo), Guercioni, G. (Gianluca), Tranà, C. (Cristian), Cui, Y. (Yijun), Kok, K.Y.Y. (Kenneth), Ghnnam, W.M. (Wagih), Abbas, A.E.S. (Ashraf El-Sayed), Sato, N. (Norio), Marwah, S. (Sanjay), Rangarajan, M. (Muthukumaran), Ben-Ishay, O. (Offir), Adesunkanmi, A.R.K. (Abdul Rashid), Segovia Lohse, H.A. (Helmut), Kenig, J. (Jakub), Mandalà, V. (Vincenzo), Patrizi, A. (Andrea), Scibé, R. (Rodolfo), and Catena, F. (Fausto)

Abstract

Emergency repair of complicated abdominal hernias is associated with poor prognosis and a high rate of post-operative complications. A World Society of Emergency Surgery (WSES) Consensus Conference was held in Bergamo in July 2013, during the 2nd Congress of the World Society of Emergency Surgery with the goal of defining recommendations for emergency repair of abdominal wall hernias in adults. This document represents the executive summary of the consensus conference approved by a WSES expert panel.

Published
2013
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13. Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2013 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group

Author

Di Saverio, S. (Salomone), Coccolini, F. (Federico), Galati, M. (Marica), Smerieri, N. (Nazareno), Biffl, W.L. (Walter), Ansaloni, L. (Luca), Tugnoli, G. (Gregorio), Velmahos, G.C. (George ), Sartelli, M. (Massimo), Bendinelli, C. (Cino), Fraga, G.P. (Gustavo), Kelly, M.D. (Michael ), Moore, F.A. (Frederick), Mandala, V., Mandalà, V. (Vincenzo), Masetti, M. (Michele), Jovine, E. (Elio), Pinna, A.D. (Antonio ), Peitzman, A.B. (Andrew), Leppaniemi, A. (Ari), Sugarbaker, P.H. (Paul ), Goor, H. (Harry) van, Moore, E.E. (Ernest), Jeekel, J. (Hans), Catena, F. (Fausto), Di Saverio, S. (Salomone), Coccolini, F. (Federico), Galati, M. (Marica), Smerieri, N. (Nazareno), Biffl, W.L. (Walter), Ansaloni, L. (Luca), Tugnoli, G. (Gregorio), Velmahos, G.C. (George ), Sartelli, M. (Massimo), Bendinelli, C. (Cino), Fraga, G.P. (Gustavo), Kelly, M.D. (Michael ), Moore, F.A. (Frederick), Mandala, V., Mandalà, V. (Vincenzo), Masetti, M. (Michele), Jovine, E. (Elio), Pinna, A.D. (Antonio ), Peitzman, A.B. (Andrew), Leppaniemi, A. (Ari), Sugarbaker, P.H. (Paul ), Goor, H. (Harry) van, Moore, E.E. (Ernest), Jeekel, J. (Hans), and Catena, F. (Fausto)

Abstract

Background: In 2013 Guidelines on diagnosis and management of ASBO have been revised and updated by the WSES Working Group on ASBO to develop current evidence-based algorithms and focus indications and safety of conservative treatment, timing of surgery and indications for laparoscopy.Recommendations: In absence of signs of strangulation and history of persistent vomiting or combined CT-scan signs (free fluid, mesenteric edema, small-bowel feces sign, devascularization) patients with partial ASBO can be managed safely with NOM and tube decompression should be attempted. These patients are good candidates for Water-Soluble-Contrast-Medium (WSCM) with both diagnostic and therapeutic purposes. The radiologic appearance of WSCM in the colon within 24 hours from administration predicts resolution. WSCM maybe administered either orally or via NGT both immediately at admission or after failed conservative treatment for 48 hours. The use of WSCM

Published
2013
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14. Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2013 update of the evidence-based guidelines from the world society of emergency surgery ASBO working group

Author

Di Saverio, S, Coccolini, F, Galati, M, Smerieri, N, Biffl, WL, Ansaloni, L, Tugnoli, G, Velmahos, GC, Sartelli, M, Bendinelli, C, Fraga, GP, Kelly, MD, Moore, FA, Mandala, V, Mandala, S, Masetti, M, Jovine, E, Pinna, AD, Peitzman, AB, Leppaniemi, A, Sugarbaker, PH, van Goor, H, Moore, EE, Jeekel, J (Hans), Catena, F, Di Saverio, S, Coccolini, F, Galati, M, Smerieri, N, Biffl, WL, Ansaloni, L, Tugnoli, G, Velmahos, GC, Sartelli, M, Bendinelli, C, Fraga, GP, Kelly, MD, Moore, FA, Mandala, V, Mandala, S, Masetti, M, Jovine, E, Pinna, AD, Peitzman, AB, Leppaniemi, A, Sugarbaker, PH, van Goor, H, Moore, EE, Jeekel, J (Hans), and Catena, F

Abstract

Background: In 2013 Guidelines on diagnosis and management of ASBO have been revised and updated by the WSES Working Group on ASBO to develop current evidence-based algorithms and focus indications and safety of conservative treatment, timing of surgery and indications for laparoscopy. Recommendations: In absence of signs of strangulation and history of persistent vomiting or combined CT-scan signs (free fluid, mesenteric edema, small-bowel feces sign, devascularization) patients with partial ASBO can be managed safely with NOM and tube decompression should be attempted. These patients are good candidates for Water-Soluble-Contrast-Medium (WSCM) with both diagnostic and therapeutic purposes. The radiologic appearance of WSCM in the colon within 24 hours from administration pre NOM, in absence of signs of strangulation or peritonitis, can be prolonged up to 72 hours. After 72 hours of NOM without resolution, surgery is recommended. Patients treated non-operatively have shorter hospital stay, but higher recurrence rate and shorter time to readmission, although the risk of new surgically treated episodes of ASBO is unchanged. Risk factors for recurrences are age <40 years and matted adhesions. WSCM does not decrease recurrence rates or recurrences needing surgery. Open surgery is often used for strangulating ASBO as well as after failed conservative management. In selected patients and with appropriate skills, laparoscopic approach is advisable using open access technique. Access in left upper quadrant or left flank is the safest and only completely obstructing adhesions should be identified and lysed with cold scissors. Laparoscopic adhesiolysis should be attempted preferably if first episode of SBO and/or anticipated single band. A low threshold for ope Peritoneal adhesions should be prevented. Hyaluronic acid-carboxycellulose membrane and icodextrin decrease incidence of adhesions. Icodextrin may reduce the risk of re-obstruction. HA cannot reduce need of surgery

Published
2013

15. EuraHS: the development of an international online platform for registration and outcome measurement of ventral abdominal wall hernia repair

Author

Muysoms, F, Campanelli, G, Champault, GG, DeBeaux, AC, Dietz, UA, Jeekel, J (Hans), Klinge, U, Kockerling, F, Mandala, V, Montgomery, A, Conde, SM, Puppe, F, Simmermacher, RKJ, Smietanski, M, Miserez, M, Muysoms, F, Campanelli, G, Champault, GG, DeBeaux, AC, Dietz, UA, Jeekel, J (Hans), Klinge, U, Kockerling, F, Mandala, V, Montgomery, A, Conde, SM, Puppe, F, Simmermacher, RKJ, Smietanski, M, and Miserez, M

Abstract

Although the repair of ventral abdominal wall hernias is one of the most commonly performed operations, many aspects of their treatment are still under debate or poorly studied. In addition, there is a lack of good definitions and classifications that make the evaluation of studies and meta-analyses in this field of surgery difficult. Under the auspices of the board of the European Hernia Society and following the previously published classifications on inguinal and on ventral hernias, a working group was formed to create an online platform for registration and outcome measurement of operations for ventral abdominal wall hernias. Development of such a registry involved reaching agreement about clear definitions and classifications on patient variables, surgical procedures and mesh materials used, as well as outcome parameters A set of well-described definitions was made. The previously reported EHS classifications of hernias will be used. Risk factors for recurrences and co-morbidities of patients were listed. A new severity of comorbidity score was defined. Post-operative complications were classified according to existing classifications as described for other fields of surgery. A new 3-dimensional numerical quality-of-life score, EuraHS-QoL score, was defined. An online platform is created based on the definitions An online platform for registration and outcome measurement of abdominal wall hernia repairs with clear definitions and classifications is offered to the surgical community. It is hoped that this registry could lead to better evidence-based guidelines for treatment of abdominal wall hernias based on hernia variables, patient variables, available hernia repair materials and techniques.

Published
2012

16. Bologna Guidelines for Diagnosis and Management of Adhesive Small Bowel Obstruction (ASBO): 2010 Evidence-Based Guidelines of the World Society of Emergency Surgery.

Author

Catena, F., Saverio, S. Di, Kelly, M.D., Biffl, W.L., Ansaloni, L., Mandala, V., Velmahos, G.C., Sartelli, M., Tugnoli, G., Lupo, M., Mandala, S., Pinna, A.D., Sugarbaker, P.H., Goor, H. van, Moore, E.E., Jeekel, J., Catena, F., Saverio, S. Di, Kelly, M.D., Biffl, W.L., Ansaloni, L., Mandala, V., Velmahos, G.C., Sartelli, M., Tugnoli, G., Lupo, M., Mandala, S., Pinna, A.D., Sugarbaker, P.H., Goor, H. van, Moore, E.E., and Jeekel, J.

Abstract

Contains fulltext : 97685.pdf (publisher's version ) (Open Access), BACKGROUND: There is no consensus on diagnosis and management of ASBO. Initial conservative management is usually safe, however proper timing for discontinuing non operative treatment is still controversial. Open surgery or laparoscopy are used without standardized indications. METHODS: A panel of 13 international experts with interest and background in ASBO and peritoneal diseases, participated in a consensus conference during the 1st International Congress of the World Society of Emergency Surgery and 9th Peritoneum and Surgery Society meeting, in Bologna, July 1-3, 2010, for developing evidence-based recommendations for diagnosis and management of ASBO. Whenever was a lack of high-level evidence, the working group formulated guidelines by obtaining consensus. RECOMMENDATIONS: In absence of signs of strangulation and history of persistent vomiting or combined CT scan signs (free fluid, mesenteric oedema, small bowel faeces sign, devascularized bowel) patients with partial ASBO can be managed safely with NOM and tube decompression (either with long or NG) should be attempted. These patients are good candidates for Water Soluble Contrast Medium (WSCM) with both diagnostic and therapeutic purposes. The appearance of water-soluble contrast in the colon on X-ray within 24 hours from administration predicts resolution. WSCM may be administered either orally or via NGT (50-150 ml) both immediately at admission or after an initial attempt of conservative treatment of 48 hours. The use of WSCM for ASBO is safe and reduces need for surgery, time to resolution and hospital stay.NOM, in absence of signs of strangulation or peritonitis, can be prolonged up to 72 hours. After 72 hours of NOM without resolution surgery is recommended.Patients treated non-operatively have shorter hospital stay, but higher recurrence rate and shorter time to re-admission, although the risk of new surgically treated episodes of ASBO is unchanged. Risk factors for recurrences are age <40 years and m

Published
2011

17. European Hernia Society classification of parastomal hernias

Author

Śmietański, M., primary, Szczepkowski, M., additional, Alexandre, J. A., additional, Berger, D., additional, Bury, K., additional, Conze, J., additional, Hansson, B., additional, Janes, A., additional, Miserez, M., additional, Mandala, V., additional, Montgomery, A., additional, Morales Conde, S., additional, and Muysoms, F., additional

Published
2013
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19. Clinical strategies for the management of intestinal obstruction and pseudo-obstruction

Author

Costa, G., Ruscelli, P., Balducci, G., Buccoliero, F., Lorenzon, L., Frezza, B., Chirletti, P., Stagnitti, F., Miniello, S., Stella, F., Agresta, F., Ansaloni, L., Basile, G., Bellanova, G., Blandamura, V., Buonanno, G. M., Calderale, S. M., Caronna, R., Casciaro, G., Catena, F., Ceci, F., Chiara, O., Chiarugi, M., Cimbanassi, S., Coccolini, F., Gianfranco Cocorullo, Manzoni, G., Di Grezia, G., Frego, M., Fusco, B., Giulini, S. M., Greco, M., Gulotta, G., Lippolis, P. V., Mandala, V., Marini, P., Martino, A., Marzaioli, R., Mecarelli, V., Mingoli, A., Mirabella, A., Morelli, M. M., Padalino, P., Picardi, N., Portolani, N., Ribaldi, S., Ricci, G., Salamone, G., Sartelli, M., Staudacher, C., Tonelli, P., Tricarico, F., Trojaniello, B., Tugnoli, G., Valeri, A., Venezia, P., Zago, M., and Obow-Sicut, The Collaborative Study Group

21. Comprehensive analysis of long-term trends, meteorological influences, and ozone formation sensitivity in the Jakarta Greater Area.

Author

Kusumaningtyas SDA, Tonokura K, Muharsyah R, Gunawan D, Sopaheluwakan A, Iriana W, Lestari P, Permadi DA, Rahmawati R, and Samputra NAR

Abstract

Jakarta Greater Area (JGA) has encountered recurrent challenges of air pollution, notably, high ozone levels. We investigate the trends of surface ozone (O 3 ) changes from the air quality monitoring stations and resolve the contribution of meteorological drivers in urban Jakarta (2010-2019) and rural Bogor sites (2017-2019) using stepwise Multi Linear Regression. During 10 years of measurement, 41% of 1-h O 3 concentrations exceeded Indonesia' s national threshold in Jakarta. In Bogor, 0.1% surpassed the threshold during 3 years of available data records. The monthly average of maximum daily 8-h average (MDA8) O 3 anomalies exhibited a downward trend at Jakarta sites while increasing at the rural site of Bogor. Meteorological and anthropogenic drivers contribute 30% and 70%, respectively, to the interannual O 3 anomalies in Jakarta. Ozone formation sensitivity with satellite demonstrates that a slight decrease in NO 2 and an increase in HCHO contributed to declining O 3 in Jakarta with 10 years average of HCHO to NO 2 ratio (FNR) of 3.7. Conversely, O 3 increases in rural areas with a higher FNR of 4.4, likely due to the contribution from the natural emission of O 3 precursors and the influence of meteorological factors that magnify the concentration., (© 2024. The Author(s).)

Published
2024
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22. Sensitivity Analysis of Parameters Affecting Wetland Water Levels: A Study of Flood Detention Basin, Colombo, Sri Lanka.

Author

Herath M, Jayathilaka T, Azamathulla HM, Mandala V, Rathnayake N, and Rathnayake U

Abstract

Wetlands play a vital role in ecosystems. They help in flood accumulation, water purification, groundwater recharge, shoreline stabilization, provision of habitats for flora and fauna, and facilitation of recreation activities. Although wetlands are hot spots of biodiversity, they are one of the most endangered ecosystems on the Earth. This is not only due to anthropogenic activities but also due to changing climate. Many studies can be found in the literature to understand the water levels of wetlands with respect to the climate; however, there is a lack of identification of the major meteorological parameters affecting the water levels, which are much localized. Therefore, this study, for the first time in Sri Lanka, was carried out to understand the most important parameters affecting the water depth of the Colombo flood detention basin. The temporal behavior of water level fluctuations was tested among various combinations of hydro-meteorological parameters with the help of Artificial Neural Networks (ANN). As expected, rainfall was found to be the most impacting parameter; however, apart from that, some interesting combinations of meteorological parameters were found as the second layer of impacting parameters. The rainfall-nighttime relative humidity, rainfall-evaporation, daytime relative humidity-evaporation, and rainfall-nighttime relative humidity-evaporation combinations were highly impactful toward the water level fluctuations. The findings of this study help to sustainably manage the available wetlands in Colombo, Sri Lanka. In addition, the study emphasizes the importance of high-resolution on-site data availability for higher prediction accuracy.

Published
2023
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