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1. EuCAPT White Paper: Opportunities and Challenges for Theoretical Astroparticle Physics in the Next Decade

Author

Batista, R. Alves, Amin, M. A., Barenboim, G., Bartolo, N., Baumann, D., Bauswein, A., Bellini, E., Benisty, D., Bertone, G., Blasi, P., Böhmer, C. G., Bošnjak, Ž., Bringmann, T., Burrage, C., Bustamante, M., Bustillo, J. Calderón, Byrnes, C. T., Calore, F., Catena, R., Cerdeño, D. G., Cerri, S. S., Chianese, M., Clough, K., Cole, A., Coloma, P., Coogan, A., Covi, L., Cutting, D., Davis, A. C., de Rham, C., di Matteo, A., Domènech, G., Drewes, M., Dietrich, T., Edwards, T. D. P., Esteban, I., Erdem, R., Evoli, C., Fasiello, M., Feeney, S. M., Ferreira, R. Z., Fialkov, A., Fornengo, N., Gabici, S., Galatyuk, T., Gaggero, D., Grasso, D., Guépin, C., Harz, J., Herrero-Valea, M., Hinderer, T., Hogg, N. B., Hooper, D. C., Iocco, F., Isern, J., Karchev, K., Kavanagh, B. J., Korsmeier, M., Kotera, K., Koyama, K., Krishnan, B., Lesgourgues, J., Said, J. Levi, Lombriser, L., Lorenz, C. S., Manconi, S., Mapelli, M., Marcowith, A., Markoff, S. B., Marsh, D. J. E., Martinelli, M., Martins, C. J. A. P., Matthews, J. H., Meli, A., Mena, O., Mifsud, J., Bertolami, M. M. Miller, Millington, P., Moesta, P., Nippel, K., Niro, V., O'Connor, E., Oikonomou, F., Paganini, C. F., Pagliaroli, G., Pani, P., Pfrommer, C., Pascoli, S., Pinol, L., Pizzuti, L., Porto, R. A., Pound, A., Quevedo, F., Raffelt, G. G., Raccanelli, A., Ramirez-Ruiz, E., Raveri, M., Renaux-Petel, S., Ricciardone, A., Khalifeh, A. Rida, Riotto, A., Roiban, R., Rubio, J., Sahlén, M., Sabti, N., Sagunski, L., Šarčević, N., Schmitz, K., Schwaller, P., Schwetz, T., Sedrakian, A., Sellentin, E., Serenelli, A., Serpico, P. D., Sfakianakis, E. I., Shalgar, S., Silvestri, A., Tamborra, I., Tanidis, K., Teresi, D., Tokareva, A. A., Tolos, L., Trojanowski, S., Trotta, R., Uhlemann, C., Urban, F. R., Vernizzi, F., van Vliet, A., Villante, F. L., Vincent, A., Vink, J., Vitagliano, E., Weniger, C., Wickenbrock, A., Winter, W., Zell, S., and Zeng, M.

Subjects
Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

Astroparticle physics is undergoing a profound transformation, due to a series of extraordinary new results, such as the discovery of high-energy cosmic neutrinos with IceCube, the direct detection of gravitational waves with LIGO and Virgo, and many others. This white paper is the result of a collaborative effort that involved hundreds of theoretical astroparticle physicists and cosmologists, under the coordination of the European Consortium for Astroparticle Theory (EuCAPT). Addressed to the whole astroparticle physics community, it explores upcoming theoretical opportunities and challenges for our field of research, with particular emphasis on the possible synergies among different subfields, and the prospects for solving the most fundamental open questions with multi-messenger observations., Comment: White paper of the European Consortium for Astroparticle Theory (EuCAPT). 135 authors, 400 endorsers, 133 pages, 1382 references

Published
2021

6. EuCAPT White Paper: Opportunities and Challenges for Theoretical Astroparticle Physics in the Next Decade

Author

Alves Batista, R., Amin, M. A., Barenboim, G., Bartolo, N., Baumann, D., Bauswein, A., Bellini, E., Benisty, D., Bertone, G., Blasi, P., Böhmer, C. G., Bošnjak, Ž., Bringmann, T., Burrage, C., Bustamante, M., Calderón Bustillo, J., Byrnes, C. T., Calore, F., Catena, R., Cerdeño, D. G., Cerri, S. S., Chianese, M., Clough, K., Cole, A., Coloma, P., Coogan, A., Covi, L., Cutting, D., Davis, A. C., Rham, C. de, Matteo, A. di, Domènech, G., Drewes, M., Dietrich, T., Edwards, T. D. P., Esteban, I., Erdem, R., Evoli, C., Fasiello, M., Feeney, S. M., Ferreira, R. Z., Fialkov, A., Fornengo, N., Gabici, S., Galatyuk, T., Gaggero, D., Grasso, D., Guépin, C., Harz, J., Herrero-Valea, M., Hinderer, T., Hogg, N. B., Hooper, D. C., Iocco, D., Isern, J., Karchev, K., Kavanagh, B. J., Korsmeier, M., Kotera, K., Koyama, K., Krishnan, B., Lesgourgues, J., Levi Said, J., Lombriser, L., Lorenz, C. S., Manconi, S., Mapelli, M., Marcowith, A., Markoff, S. B., Marsh, D. J., Martinelli, M., Martinsolami, C. J. A. P., Millington, P., Moesta, P., Nippel, K., Niro, V., O'Connor, E., Oikonomou, F., Paganini, C. F., Pagliaroli, G., P. Pani, P., Pfrommer, C., Pascoli, S., Pinol, L., Pizzuti, L., Porto, R. A., Pound, A., Quevedo, F., Raffelt, G. G., Raccanelli, A., Ramirez-Ruiz, E., Raveri, M., Renaux-Petel, S., Ricciardone, A., Rida Khalifeh, A., Riotto, A., Roiban, R., Rubio, J., Sahlén, M., Sabti, N., Sagunski, L., Šarčević, N., Schmitz, K., Schwaller, P., Schwetz, T., Sedrakian, A., Sellentin, E., Serenelli, A., Serpico, P. D., Sfakianakis, E. I., Shalgar, S., Silvestri, A., Tamborra, I., Tanidis, K., Teresi, D., Tokareva, A. A., Tolos, L., Trojanowski, S., Trotta, R., Uhlemann, C., Urban, F. R., Vernizzi, F., Vliet, A. van, Villante, F. L., Vincent, A., Vink, J., Vitagliano, E., Weniger, C., Wickenbrock, A., Winter, W., Zell, S., and Zeng, M.

Subjects
Physics, ddc:530
Published
2021
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7. Do the Geminga, Monogem and PSR J0622+3749 γ-ray halos imply slow diffusion around pulsars?

Author

Recchia, S., Di Mauro, M., Aharonian, F. A., Orusa, L., Donato, F., Gabici, S., Manconi, S., AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)

Subjects
Hochenergie-Astrophysik Theorie - Abteilung Hinton, 010308 nuclear & particles physics, Astrophysics::High Energy Astrophysical Phenomena, 0103 physical sciences, Astrophysics - High Energy Astrophysical Phenomena, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], 010303 astronomy & astrophysics, 01 natural sciences
Abstract

The HAWC Collaboration has reported the detection of an extended $\gamma$-ray emission around the Geminga and Monogem pulsars of a few degree extension. Very recently, the LHAASO Collaboration released also the data for an extended $\gamma$-ray emission around the pulsar PSR J0622+3749. This flux can be explained with electrons and positrons injected from these sources and their inverse Compton Scattering on the interstellar radiation fields. So far the size of such $\gamma-$ray halos has been interpreted as the result of the diffusion coefficient around the sources being about two orders of magnitude smaller than the average in the Galaxy. However, this conclusion is driven by the assumption that particles propagate diffusively right away after the injection without taking into account the ballistic propagation. The propagation of cosmic-ray leptons in the proximity of the Geminga, Monogem and PSR J0622+3749 pulsars is examined here considering the transition from the quasi-ballistic, valid for the most recently injected particles, to the diffusive transport regime. For typical interstellar values of the diffusion coefficient, the quasi-ballistic regime dominates the lepton distribution up to distances of a few tens of parsec from the pulsar for particle energies above $\sim 10$ TeV. In this regime the resulting $\gamma-$ray source tends to be rather compact, despite particles travel a long distance. Indeed, for larger values of the diffusion coefficient, particles propagate ballistically up to larger distances with the result of a more point-like $\gamma-$ray source. When such transition is taken into account, a good fit to the HAWC and LHAASO $\gamma-$ray data around Geminga, Monogem and PSR J0622+3749 is obtained without the need to invoke a strong suppression of the diffusion coefficient., Comment: 10 pages, 4 figures. This version includes other two sources (Monogem and PSR J0622+3749) with respect to the first version

Published
2021
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8. Cosmic ray transport in the proximity of pulsars and the formation of gamma-ray halos

Author

Recchia, S., Di Mauro, M., Aharonian, F., Donato, F., Gabici, S., Manconi, S., AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)

Subjects
cosmic radiation: propagation, gamma ray: halo, Astrophysics::High Energy Astrophysical Phenomena, galaxy: model, halo: formation, turbulence, diffusion, Hochenergie-Astrophysik Theorie - Abteilung Hinton, gamma ray: emission, cosmic radiation: galaxy, transport theory, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], HAWC, pulsar
Abstract

International audience; The detection of an extended multi-TeV gamma ray emission around the Geminga and Monogempulsars by the HAWC collaboration provides a unique tool to investigate the transport properties ofcosmic rays in the turbulent magnetized interstellar medium. Previous analyses of such emissionin the framework of pure isotropic diffusion lead to infer a suppression of the diffusion coefficientin the pulsars region by at least two orders of magnitude compared to typical values found inmodels of Galactic cosmic ray propagation. In this work, we investigate the transition from theballistic to the diffusive regime, and show that, when such transition is taken into account, a goodfit to the HAWC γ−ray data around Geminga and Monogem is obtained with typical values of theinterstellar diffusion coefficient.

Published
2021
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9. EuCAPT White Paper : Opportunities and Challenges for Theoretical Astroparticle Physics in the Next Decade

Author

Alves-Batista, R., Amin, M. A., Barenboim, G., Bartolo, N., Baumann, D., Bauswein, A., Bellini, E., Benisty, D., Bertone, G., Blasi, P., Böhmer, C. G., Bošnjak, Ž, Bringmann, T., Burrage, C., Bustamante, M., Calderón Bustillo, J., Byrnes, C. T., Calore, F., Catena, R., Cerdeño, D. G., Cerri, S. S., Chianese, M., Clough, K., Cole, A., Coloma, P., Coogan, A., Covi, L., Cutting, D., Davis, A. C., de Rham, C., di Matteo, A., Domènech, G., Drewes, M., Dietrich, T., Edwards, T. D. P., Esteban, I., Erdem, R., Evoli, C., Fasiello, M., Feeney, S. M., Ferreira, R. Z., Fialkov, A., Fornengo, N., Gabici, S., Galatyuk, T., Gaggero, D., Grasso, D., Guépin, C., Harz, J., Herrero-Valea, M., Hinderer, T., Hogg, N. B., Hooper, D. C., Iocco, F., Isern, J., Karchev, K., Kavanagh, B. J., Korsmeier, M., Kotera, K., Koyama, K., Krishnan, B., Lesgourgues, J., Levi Said, J., Lombriser, L., Lorenz, C. S., Manconi, S., Mapelli, M., Marcowith, A., Markoff, S. B., Marsh, D. J. E., Martinelli, M., Martins, C. J. A. P., Matthews, J. H., Meli, A., Mena, O., Mifsud, J., Miller Bertolami, M. M., Millington, P., Moesta, P., Nippel, K., Niro, V., O’Connor, E., Oikonomou, F., Paganini, C. F., Pagliaroli, G., Pani, P., Pfrommer, C., Pascoli, S., Pinol, L., Pizzuti, L., Porto, R. A., Pound, A., Quevedo, F., Raffelt, G. G., Raccanelli, A., Ramirez-Ruiz, E., Raveri, M., Renaux-Petel, S., Ricciardone, A., Rida Khalifeh, A., Riotto, A., Roiban, R., Rubio, J., Sahlén, M., Sabti, N., Sagunski, L., Šarčević, N., Schmitz, K., Schwaller, P., Schwetz, T., Sedrakian, A., Sellentin, E., Serenelli, A., Serpico, P. D., Sfakianakis, E. I., Shalgar, S., Silvestri, A., Tamborra, I., Tanidis, K., Teresi, D., Tokareva, A. A., Tolos, L., Trojanowski, S., Trotta, R., Uhlemann, C., Urban, F. R., Vernizzi, F., van Vliet, A., Villante, F. L., Vincent, A., Vink, J., Vitagliano, E., Weniger, C., Wickenbrock, A., Winter, W., Zell, S., Zeng, M., Alves-Batista, R., Amin, M. A., Barenboim, G., Bartolo, N., Baumann, D., Bauswein, A., Bellini, E., Benisty, D., Bertone, G., Blasi, P., Böhmer, C. G., Bošnjak, Ž, Bringmann, T., Burrage, C., Bustamante, M., Calderón Bustillo, J., Byrnes, C. T., Calore, F., Catena, R., Cerdeño, D. G., Cerri, S. S., Chianese, M., Clough, K., Cole, A., Coloma, P., Coogan, A., Covi, L., Cutting, D., Davis, A. C., de Rham, C., di Matteo, A., Domènech, G., Drewes, M., Dietrich, T., Edwards, T. D. P., Esteban, I., Erdem, R., Evoli, C., Fasiello, M., Feeney, S. M., Ferreira, R. Z., Fialkov, A., Fornengo, N., Gabici, S., Galatyuk, T., Gaggero, D., Grasso, D., Guépin, C., Harz, J., Herrero-Valea, M., Hinderer, T., Hogg, N. B., Hooper, D. C., Iocco, F., Isern, J., Karchev, K., Kavanagh, B. J., Korsmeier, M., Kotera, K., Koyama, K., Krishnan, B., Lesgourgues, J., Levi Said, J., Lombriser, L., Lorenz, C. S., Manconi, S., Mapelli, M., Marcowith, A., Markoff, S. B., Marsh, D. J. E., Martinelli, M., Martins, C. J. A. P., Matthews, J. H., Meli, A., Mena, O., Mifsud, J., Miller Bertolami, M. M., Millington, P., Moesta, P., Nippel, K., Niro, V., O’Connor, E., Oikonomou, F., Paganini, C. F., Pagliaroli, G., Pani, P., Pfrommer, C., Pascoli, S., Pinol, L., Pizzuti, L., Porto, R. A., Pound, A., Quevedo, F., Raffelt, G. G., Raccanelli, A., Ramirez-Ruiz, E., Raveri, M., Renaux-Petel, S., Ricciardone, A., Rida Khalifeh, A., Riotto, A., Roiban, R., Rubio, J., Sahlén, M., Sabti, N., Sagunski, L., Šarčević, N., Schmitz, K., Schwaller, P., Schwetz, T., Sedrakian, A., Sellentin, E., Serenelli, A., Serpico, P. D., Sfakianakis, E. I., Shalgar, S., Silvestri, A., Tamborra, I., Tanidis, K., Teresi, D., Tokareva, A. A., Tolos, L., Trojanowski, S., Trotta, R., Uhlemann, C., Urban, F. R., Vernizzi, F., van Vliet, A., Villante, F. L., Vincent, A., Vink, J., Vitagliano, E., Weniger, C., Wickenbrock, A., Winter, W., Zell, S., and Zeng, M.

Published
2021
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11. CARDIOINSIGHT: A NEW MAPPING SYSTEM

Author

Bianco Dolino, E, Manconi, S, and Gallone, G

Abstract

Cardioinsight is a non–invasive mapping system that collects chest ECG signals and combines them with CT scan data to produce and display simultaneous biatrial and biventricular three–dimensional cardiac maps. Cardioinsight is intended for the collection, analysis, visualization and storage of cardiac electrophysiology data and maps for subsequent medical analysis. It is therefore a device capable of identifying the point from which cardiac arrhythmias originate. Cardioinsight is an innovative system as until 2018 electrophysiological studies were used to study the electrical properties of the heart. The substantial difference between Cardioinsight and electrophysiological studies is that Cardioinsight is non–invasive and allows the point from which the arrhythmia arises to be identified without the need to resort to catheterization and therefore leading to zero risk of intra–procedural and post–procedural complications. The Cardioinsight consists of: the mapping vest and the Workstation. The mapping vest is a non–sterile, disposable device that includes: 3 panels: front right, front left and rear 252 electrodes Connectors that connect the mapping vest to the system The Cardioinsight Workstation consists of the monitor and the amplifier and is always used with the Cardioinsight mapping vest. Cardioinsight has 3 advantages: it is not invasive 3D simultaneous multi–camera mapping: Capable of capturing rhythms that span multiple cameras) a single heartbeat is enough to generate maps.The use of Cardioinsight requires 3 phases: Prepare the patient and apply the vest Obtain a CT scan and record the signals Combine CT and signal data to create maps The doctor analyzes the maps and plans the next step of care for the patient Treatment can be catheter ablation or stereotactic ablation. The latter provides an alternative therapeutic strategy to traditional ablation as it is non–invasive and painless and consists in the administration of precise and targeted doses of radiation which produce tissue damage resulting in cell death. In our reality we have had the opportunity to use Cardioinsight twice and it has been established that it is a valid alternative to traditional mapping with advantages for the patient and for an optimal path in the search for the most appropriate therapeutic approach.

Published
2024
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14. Theoretical Interpretation of Pass 8Fermi-LATe++e−Data

Author

Di Mauro, M., primary, Manconi, S., additional, Vittino, A., additional, Donato, F., additional, Fornengo, N., additional, Baldini, L., additional, Bonino, R., additional, Di Lalla, N., additional, Latronico, L., additional, Maldera, S., additional, Manfreda, A., additional, Negro, M., additional, Pesce-Rollins, M., additional, Sgrò, C., additional, and Spada, F., additional

Published
2017
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18. A Model for Scuffing Prediction

Author

Enrico Ciulli, Bartilotta, I., Polacco, A., Manconi, S., Vela, D., and Paleotti, F. S. G.

Subjects
scuffing
Published
2010

20. Ingranaggi ad alte prestazioni

Author

Manfredi, Enrico, Ciulli, Enrico, Manconi, S., Iliano, S., and Polacco, A.

Subjects
ingranaggi
Published
2009

34. Evidence for dopamine receptors in the human brain mediating sedation and sleep

Author

Pierluigi Onali, M.P. Piccardi, M. Del Zompo, Manconi S, G.L. Gessa, A. Mangoni, and Giovanni Umberto Corsini

Subjects
Adult, Male, Apomorphine, Sedation, General Biochemistry, Genetics and Molecular Biology, Receptors, Dopamine, Dopamine receptor D1, Dopamine receptor D3, Dopamine receptor D2, medicine, Humans, Hypnotics and Sedatives, General Pharmacology, Toxicology and Pharmaceutics, business.industry, Brain, General Medicine, Human brain, Sleep in non-human animals, medicine.anatomical_structure, Dopamine receptor, Anesthesia, Schizophrenia, Haloperidol, Female, medicine.symptom, business, Sleep, Neuroscience, Endogenous agonist
Published
1977

35. EuCAPT White Paper: Opportunities and Challenges for Theoretical Astroparticle Physics in the Next Decade

Author

Alves Batista, R., Amin, M. A., Barenboim, G., Bartolo, N., Baumann, D., Bauswein, A., Bellini, E., Benisty, D., Bertone, Giantranco, Blasi, P., B��hmer, C. G., Bo��njak, ��., Bringmann, T., Burrage, C., Bustamante, M., Bustillo, J. Calder��n, Byrnes, C. T., Calore, F., Catena, R., Cerde��o, D. G., Cerri, S. S., Chianese, M., Clough, K., Cole, A., Coloma, P., Coogan, A., Covi, L., Cutting, D., Davis, A. C., de Rham, C., di Matteo, A., Dom��nech, G., Drewes, M., Dietrich, T., Edwards, T. D. P., Esteban, I., Erdem, R., Evoli, C., Fasiello, M., Feeney, S. M., Ferreira, R. Z., Fialkov, A., Fornengo, N., Gabici, S., Galatyuk, T., Gaggero, D., Grasso, D., Gu��pin, C., Harz, J., Herrero-Valea, M., Hinderer, T., Hogg, N. B., Hooper, D. C., Iocco, F., Isern, J., Karchev, K., Kavanagh, B. J., Korsmeier, M., Kotera, K., Koyama, K., Krishnan, B., Lesgourgues, J., Said, J. Levi, Lombriser, L., Lorenz, C. S., Manconi, S., Mapelli, M., Marcowith, A., Markoff, S. B., Marsh, D. J. E., Martinelli, M., Martins, C. J. A. P., Matthews, J. H., Meli, A., Mena, O., Mifsud, J., Bertolami, M. M. Miller, Millington, P., Moesta, P., Nippel, K., Niro, V., O'Connor, E., Oikonomou, F., Paganini, C. F., Pagliaroli, G., Pani, P., Pfrommer, C., Pascoli, S., Pinol, L., Pizzuti, L., Porto, R. A., Pound, A., Quevedo, F., Raffelt, G. G., Raccanelli, A., Ramirez-Ruiz, E., Raveri, M., Renaux-Petel, S., Ricciardone, A., Khalifeh, A. Rida, Riotto, A., Roiban, R., Rubio, J., Sahl��n, M., Sabti, N., Sagunski, L., ��ar��evi��, N., Schmitz, K., Schwaller, P., Schwetz, T., Sedrakian, A., Sellentin, E., Serenelli, A., Serpico, P. D., Sfakianakis, E. I., Shalgar, S., Silvestri, A., Tamborra, I., Tanidis, K., Teresi, D., Tokareva, A. A., Tolos, L., Trojanowski, S., Trotta, R., Uhlemann, C., Urban, F. R., Vernizzi, F., van Vliet, A., Villante, F. L., Vincent, A., Vink, J., Vitagliano, E., Weniger, C., Wickenbrock, A., Winter, W., Zell, S., Zeng, M., HEP, INSPIRE, Laboratoire d'Annecy-le-Vieux de Physique Théorique (LAPTH), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Joseph Louis LAGRANGE (LAGRANGE), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Univers et Particules de Montpellier (LUPM), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Institut de Physique Théorique - UMR CNRS 3681 (IPHT), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)

Subjects
Astrophysics and Astronomy, Cosmology and Nongalactic Astrophysics (astro-ph.CO), accelerator, WIMP, FOS: Physical sciences, cosmic background radiation, gravitational radiation: direct detection, dark matter, IceCube, X-ray, statistical analysis, ultraviolet, supernova, black hole, LIGO, dark energy, neutron star, white dwarf, High Energy Astrophysical Phenomena (astro-ph.HE), astro-ph.HE, LISA, electroweak interaction, oscillation [neutrino], flavor [neutrino], solar, messenger, VIRGO, CERN LHC Coll, gamma ray, cosmic radiation, correlation, neutrino: flavor, astro-ph.CO, direct detection [gravitational radiation], neutrino: oscillation, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], [PHYS.ASTR] Physics [physics]/Astrophysics [astro-ph], Astrophysics - High Energy Astrophysical Phenomena, Lorentz, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

Astroparticle physics is undergoing a profound transformation, due to a series of extraordinary new results, such as the discovery of high-energy cosmic neutrinos with IceCube, the direct detection of gravitational waves with LIGO and Virgo, and many others. This white paper is the result of a collaborative effort that involved hundreds of theoretical astroparticle physicists and cosmologists, under the coordination of the European Consortium for Astroparticle Theory (EuCAPT). Addressed to the whole astroparticle physics community, it explores upcoming theoretical opportunities and challenges for our field of research, with particular emphasis on the possible synergies among different subfields, and the prospects for solving the most fundamental open questions with multi-messenger observations., Comment: White paper of the European Consortium for Astroparticle Theory (EuCAPT). 135 authors, 400 endorsers, 133 pages, 1382 references

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36. Some remarks on the use of TaqI to detect highly repetitive DNA sequences in human chromosomes

Author

Mariella Nieddu, Pichiri, G., Manconi, S., and Mezzanotte, R.

Subjects
lcsh:Biology (General), lcsh:QH301-705.5
Abstract

In the attempt to conclude investigation of the action of restriction endonucleases on eukaryote chromosomes, we carried out a series of experiments digesting in situ human metaphase chromosomes with AluI/TaqI followed by Giemsa staining. We focused on the centromeric regions of chromosomes1, 2 and 16 and noted that those areas appeared as intensely stained blocks after AluI digestion, but were dramatically reduced in size or completely destroyed after subsequent TaqI treatment. These results permitted us to draw some conclusions on the highly repetitive DNA composition of these regions, in terms of alphoid and classical satellite DNAs.

38. Dark Matter Constraints from Planck Observations of the Galactic Polarized Synchrotron Emission.

Author

Manconi S, Cuoco A, and Lesgourgues J

Abstract

Dark matter (DM) annihilation in our Galaxy may produce a linearly polarized synchrotron signal. We use, for the first time, synchrotron polarization to constrain the DM annihilation cross section by comparing theoretical predictions with the latest polarization maps obtained by the Planck satellite collaboration. We find that synchrotron polarization is typically more constraining than synchrotron intensity by about 1 order of magnitude, independently of uncertainties in the modeling of electron and positron propagation, or of the Galactic magnetic field. Our bounds compete with cosmic microwave background limits in the case of leptophilic DM.

Published
2022
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39. Some remarks on the use of TaqI to detect highly repetitive DNA sequences in human chromosomes.

Author

Nieddu M, Pichiri G, Manconi S, and Mezzanotte R

Subjects
Azure Stains, Humans, Leukocytes, Mononuclear cytology, Leukocytes, Mononuclear metabolism, Metaphase, Repetitive Sequences, Nucleic Acid genetics, Taq Polymerase, Chromosomes, Human chemistry, DNA analysis, Deoxyribonucleases, Type II Site-Specific metabolism
Abstract

In the attempt to conclude investigation of the action of restriction endonucleases on eukaryote chromosomes, we carried out a series of experiments digesting in situ human metaphase chromosomes with AluI/TaqI followed by Giemsa staining. We focused on the centromeric regions of chromosomes1, 2 and 16 and noted that those areas appeared as intensely stained blocks after AluI digestion, but were dramatically reduced in size or completely destroyed after subsequent TaqI treatment. These results permitted us to draw some conclusions on the highly repetitive DNA composition of these regions, in terms of alphoid and classical satellite DNAs.

Published
2006

40. [Brain phospholipids and cerebrovascular insufficiency].

Author

Manconi S, Piccardi MP, and Corsini GU

Subjects
Adult, Aged, Drug Evaluation, Drug Therapy, Combination, Female, Humans, Male, Middle Aged, Time Factors, Brain metabolism, Cerebrovascular Disorders drug therapy, Phospholipids therapeutic use
Published
1980

41. Sedative, hypnotic, and antipsychotic effects of low doses of apomorphine in man.

Author

Corsini GU, Del Zompo M, Manconi S, Cianchetti C, Mangoni A, and Gessa GL

Subjects
Adolescent, Adult, Apomorphine administration & dosage, Bipolar Disorder physiopathology, Drug Interactions, Female, Haloperidol pharmacology, Humans, Male, Schizophrenia physiopathology, Sulpiride pharmacology, Antipsychotic Agents, Apomorphine pharmacology, Hypnotics and Sedatives
Published
1977

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