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1. 224 Artificial Intelligence-based Decision Support Predicts Requirement for Neurosurgical Intervention in Acute Traumatic Brain Injury: Automated Surgical Intervention Support Tool (ASIST-TBI) Development, Validation and Simulated Prospective Deployment

Author

Malhotra, Armaan K., primary, Smith, Christopher, additional, Shakil, Husain, additional, Ackery, Alun, additional, Mamdani, M., additional, Nathens, Avery, additional, Wilson, Jefferson, additional, Colak, Errol, additional, and Witiw, Christopher, additional

Published
2024
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2. A simplified (modified) Duke Activity Status Index (M-DASI) to characterise functional capacity: a secondary analysis of the Measurement of Exercise Tolerance before Surgery (METS) study

Author

Wallace, S., Thompson, B., Ellis, M., Borg, B., Kerridge, R.K., Douglas, J., Brannan, J., Pretto, J., Godsall, M.G., Beauchamp, N., Allen, S., Kennedy, A., Wright, E., Malherbe, J., Ismail, H., Riedel, B., Melville, A., Sivakumar, H., Murmane, A., Kenchington, K., Kirabiyik, Y., Gurunathan, U., Stonell, C., Brunello, K., Steele, K., Tronstad, O., Masel, P., Dent, A., Smith, E., Bodger, A., Abolfathi, M., Sivalingam, P., Hall, A., Painter, T.W., Macklin, S., Elliott, A., Carrera, A.M., Terblanche, N.C.S., Pitt, S., Samuels, J., Wilde, C., Leslie, K., MacCormick, A., Bramley, D., Southcott, A.M., Grant, J., Taylor, H., Bates, S., Towns, M., Tippett, A., Marshall, F., Mazer, C.D., Kunasingam, J., Yagnik, A., Crescini, C., Yagnik, S., McCartney, C.J.L., Choi, S., Somascanthan, P., Flores, K., Au, S., Beattie, W.S., Karkouti, K., Clarke, H.A., Jerath, A., McCluskey, S.A., Wasowicz, M., Day, L., Pazmino-Canizares, J., Oh, P., Belliard, R., Lee, L., Dobson, K., Chan, V., Brull, R., Ami, N., Stanbrook, M., Hagen, K., Campbell, D., Short, T., Van Der Westhuizen, J., Higgie, J.K., Lindsay, H., Jang, R., Wong, C., Mcallister, D., Ali, M., Kumar, J., Waymouth, E., Kim, C., Dimech, J., Lorimer, M., Tai, J., Miller, R., Sara, R., Collingwood, A., Olliff, S., Gabriel, S., Houston, H., Dalley, P., Hurford, S., Hunt, A., Andrews, L., Navarra, L., Jason-Smith, A., Thompson, H., McMillan, N., Back, G., Lum, M., Martin, D., S James, S., Filipe, H., Pinto, M., Kynaston, S., Phull, M., Beilstein, C., Bodger, P., Everingham, K., Hu, Y., Niebrzegowska, E., Corriea, C., Creary, T., Januszewska, M., Ahmad, T., Whalley, J., Haslop, R., McNeil, J., Brown, A., MacDonald, N., Pakats, M., Greaves, K., Jhanji, S., Raobaikady, R., Black, E., Rooms, M., Lawrence, H., Koutra, M., Pirie, K., Gertsman, M., Jack, S., Celinski, M., Levett, D., Edwards, M., Salmon, K., Bolger, C., Loughney, L., Seaward, L., Collins, H., Tyrell, B., Tantony, N., Golder, K., Ackland, G.L., Stephens, R.C.M., Gallego-Paredes, L., Reyes, A., Gutierrez del Arroyo, A., Raj, A., R Lifford, R., Melo, M., Mamdani, M., Hillis, G., Wijeysundera, H.C., Riedel, Bernhard, Li, Michael H-G., Lee, C.H. Angus, Ismail, Hilmy, Cuthbertson, Brian H., Wijeysundera, Duminda N., and Ho, Kwok M.

Published
2021
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3. Integration of the Duke Activity Status Index into preoperative risk evaluation: a multicentre prospective cohort study

Author

Cuthbertson, B.H., Wijeysundera, D.N., Pearse, R.M., Myles, P.S., Abbott, T.E.F., Shulman, M.A., Torres, E., Ambosta, A., Melo, M., Mamdani, M., Thorpe, K.E., Wallace, S., Farrington, C., Croal, B.L., Grocott, M.P.W., Granton, J.T., Oh, P., Thompson, B., Levett, D., Hillis, G., Beattie, W.S., Wijeysundera, H.C., Wijeysundera, Duminda N., Beattie, W. Scott, Hillis, Graham S., Abbott, Tom E.F., Shulman, Mark A., Ackland, Gareth L., Mazer, C. David, Myles, Paul S., Pearse, Rupert M., Cuthbertson, Brian H., Ellis, M., Borg, B., Kerridge, R.K., Douglas, J., Brannan, J., Pretto, J., Godsall, M.G., Beauchamp, N., Allen, S., Kennedy, A., Wright, E., Malherbe, J., Ismail, H., Riedel, B., Melville, A., Sivakumar, H., Murmane, A., Kenchington, K., Kirabiyik, Y., Gurunathan, U., Stonell, C., Brunello, K., Steele, K., Tronstad, O., Masel, P., Dent, A., Smith, E., Bodger, A., Abolfathi, M., Sivalingam, P., Hall, A., Painter, T.W., Macklin, S., Elliott, A., Carrera, A.M., Terblanche, N.C.S., Pitt, S., Samuels, J., Wilde, C., Leslie, K., MacCormick, A., Bramley, D., Southcott, A.M., Grant, J., Taylor, H., Bates, S., Towns, M., Tippett, A., Marshall, F., Mazer, C.D., Kunasingam, J., Yagnik, A., Crescini, C., Yagnik, S., McCartney, C.J.L., Choi, S., Somascanthan, P., Flores, K., Karkouti, K., Clarke, H.A., Jerath, A., McCluskey, S.A., Wasowicz, M., Day, L., Pazmino-Canizares, J., Belliard, R., Lee, L., Dobson, K., Chan, V., Brull, R., Ami, N., Stanbrook, M., Hagen, K., Campbell, D., Short, T., Van Der Westhuizen, J., Higgie, K., Lindsay, H., Jang, R., Wong, C., Mcallister, D., Ali, M., Kumar, J., Waymouth, E., Kim, C., Dimech, J., Lorimer, M., Tai, J., Miller, R., Sara, R., Collingwood, A., Olliff, S., Gabriel, S., Houston, H., Dalley, P., Hurford, S., Hunt, A., Andrews, L., Navarra, L., Jason-Smith, A., Thompson, H., McMillan, N., Back, G., Lum, M., Martin, D., James, S., Filipe, H., Pinto, M., Kynaston, S., Phull, M., Beilstein, C., Bodger, P., Everingham, K., Hu, Y., Niebrzegowska, E., Corriea, C., Creary, T., Januszewska, M., Ahmad, T., Whalley, J., Haslop, R., McNeil, J., Brown, A., MacDonald, N., Pakats, M., Greaves, K., Jhanji, S., Raobaikady, R., Black, E., Rooms, M., Lawrence, H., Koutra, M., Pirie, K., Gertsman, M., Jack, S., Celinski, M., Edwards, M., Salmon, K., Bolger, C., Loughney, L., Seaward, L., Collins, H., Tyrell, B., Tantony, N., Golder, K., Ackland, G.L., Stephens, R.C.M., Gallego-Paredes, L., Reyes, A., Gutierrez del Arroyo, A., Raj, A., and Lifford, R.

Published
2020
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4. Association of preoperative anaemia with cardiopulmonary exercise capacity and postoperative outcomes in noncardiac surgery: a substudy of the Measurement of Exercise Tolerance before Surgery (METS) Study

Author

Myles, P.S., Shulman, M.A., Wallace, S., Farrington, C., Thompson, B., Ellis, M., Borg, B., Kerridge, R.K., Douglas, J., Brannan, J., Pretto, J., Godsall, M.G., Beauchamp, N., Allen, S., Kennedy, A., Wright, E., Malherbe, J., Ismail, H., Riedel, B., Melville, A., Sivakumar, H., Murmane, A., Kenchington, K., Kirabiyik, Y., Gurunathan, U., Stonell, C., Brunello, K., Steele, K., Tronstad, O., Masel, P., Dent, A., Smith, E., Bodger, A., Abolfathi, M., Sivalingam, P., Hall, A., Painter, T.W., Macklin, S., Elliott, A., Carrera, A.M., Terblanche, N.C.S., Pitt, S., Samuels, J., Wilde, C., Leslie, K., MacCormick, A., Bramley, D., Southcott, A.M., Grant, J., Taylor, H., Bates, S., Towns, M., Tippett, A., Marshall, F., Mazer, C.D., Kunasingam, J., Yagnik, A., Crescini, C., Yagnik, S., McCartney, C.J.L., Choi, S., Somascanthan, P., Flores, K., Wijeysundera, D.N., Beattie, W.S., Karkouti, K., Clarke, H.A., Jerath, A., McCluskey, S.A., Wasowicz, M., Granton, J.T., Day, L., Pazmino-Canizares, J., Oh, P., Belliard, R., Lee, L., Dobson, K., Chan, V., Brull, R., Ami, N., Stanbrook, M., Hagen, K., Campbell, D., Short, T., Van Der Westhuizen, J., Higgie, K., Lindsay, H., Jang, R., Wong, C., Mcallister, D., Ali, M., Kumar, J., Waymouth, E., Kim, C., Dimech, J., Lorimer, M., Tai, J., Miller, R., Sara, R., Collingwood, A., Olliff, S., Gabriel, S., Houston, H., Dalley, P., Hurford, S., Hunt, A., Andrews, L., Navarra, L., Jason-Smith, A., Thompson, H., McMillan, N., Back, G., Croal, B.L., Lum, M., Martin, D., James, S., Filipe, H., Pinto, M., Kynaston, S., Pearse, R.M., Abbott, T.E.F., Phull, M., Beilstein, C., Bodger, P., Everingham, K., Hu, Y., Niebrzegowska, E., Corriea, C., Creary, T., Januszewska, M., Ahmad, T., Whalley, J., Haslop, R., McNeil, J., Brown, A., MacDonald, N., Pakats, M., Greaves, K., Jhanji, S., Raobaikady, R., Black, E., Rooms, M., Lawrence, H., Koutra, M., Pirie, K., Gertsman, M., Jack, S., Celinski, M., Levett, D., Edwards, M., Salmon, K., Bolger, C., Loughney, L., Seaward, L., Collins, H., Tyrell, B., Tantony, N., Golder, K., Ackland, G.L., Gallego-Paredes, L., Reyes, A., Gutierrez del Arroyo, A., Raj, A., Lifford, R., Cuthbertson, B.H., Torres, E., Ambosta, A., Melo, M., Mamdani, M., Thorpe, K.E., Grocott, M.P.W., Hillis, G., Wijeysundera, H.C., Bartoszko, J., and Laupacis, A.

Published
2019
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5. Using the 6-minute walk test to predict disability-free survival after major surgery

Author

Wallace, S., Thompson, B., Ellis, M., Borg, B., Kerridge, R.K., Douglas, J., Brannan, J., Pretto, J., Godsall, M.G., Beauchamp, N., Allen, S., Kennedy, A., Wright, E., Malherbe, J., Ismail, H., Riedel, B., Melville, A., Sivakumar, H., Murmane, A., Kenchington, K., Gurunathan, U., Stonell, C., Brunello, K., Steele, K., Tronstad, O., Masel, P., Dent, A., Smith, E., Bodger, A., Abolfathi, M., Sivalingam, P., Hall, A., Painter, T., Macklin, S., Elliott, A., Carrera, A.M., Terblanche, N.C.S., Pitt, S., Samuels, J., Wilde, C., MacCormick, A., Leslie, K., Bramley, D., Southcott, A.M., Grant, J., Taylor, H., Bates, S., Towns, M., Tippett, A., Marshall, F., McCartney, C.J.L., Choi, S., Somascanthan, P., Flores, K., Beattie, W.S., Karkouti, K., Clarke, H.A., Jerath, A., McCluskey, S.A., Wasowicz, M., Granton, J.T., Day, L., Pazmino-Canizares, J., Hagen, K., Campbell, D., Short, T., Van Der Westhuizen, J., Higgie, K., Lindsay, H., Jang, R., Wong, C., Mcallister, D., Ali, M., Kumar, J., Waymouth, E., Kim, C., Dimech, J., Lorimer, M., Tai, J., Miller, R., Sara, R., Collingwood, A., Olliff, S., Gabriel, S., Houston, H., Dalley, P., Hurford, S., Hunt, A., Andrews, L., Navarra, L., Jason-Smith, A., Thompson, H., McMillan, N., Back, G., Melo, M., Mamdani, M., Hillis, G., Wijeysundera, H.C., Shulman, M.A., Cuthbertson, B.H., Wijeysundera, D.N., Pearse, R.M., Torres, E., Ambosta, A., Farrington, C., and Myles, P.S.

Published
2019
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9. Oncological benefit of re-resection for T1 bladder cancer: a comparative effectiveness study

Author

Wettstein, MS, Baxter, NN, Sutradhar, R, Mamdani, M, Song, P, Qadri, SR, Li, K, Liu, N, van der Kwast, T, Hermanns, T, Kulkarni, GS, Wettstein, MS, Baxter, NN, Sutradhar, R, Mamdani, M, Song, P, Qadri, SR, Li, K, Liu, N, van der Kwast, T, Hermanns, T, and Kulkarni, GS

Abstract

OBJECTIVES: To quantify the real-world survival benefit of re-resection vs no re-resection in patients diagnosed with T1 bladder cancer (BC) at the population level. PATIENTS AND METHODS: Retrospective population-wide observational cohort study based on pathology reports linked to health administrative data. We identified patients who were diagnosed with T1 BC in the province of Ontario (01/2001-12/2015) and used billing claims to ascertain whether they received re-resection within 2-10 weeks. The time-dependent effect of re-resection on survival outcomes was modelled by Cox proportional hazards regression (unadjusted and adjusted for numerous assumed patient- and surgeon-level confounding variables). Effect measures were presented as hazard ratios (HRs) and 95% confidence intervals (CIs). RESULTS: We identified 7666 patients of which 2162 (28.7%) underwent re-resection after a median (interquartile range) time of 45 (35-56) days. Patients who received re-resection were less likely to die from any causes (HR 0.68, 95% CI 0.63-0.74, P < 0.001) and from BC (HR 0.66, 95% CI 0.57-0.76, P < 0.001) during any time of follow-up. After adjusting for all assumed confounding variables, re-resection was still significantly associated with a lower overall mortality (HR 0.88, 95% CI 0.81-0.95, P < 0.001), while the association with cancer-specific survival marginally lost its statistical significance (HR 0.87, 95% CI 0.75-1.02, P = 0.08). CONCLUSIONS: A second transurethral resection within 2-6 weeks after the initial resection (i.e. re-resection) is recommended for patients diagnosed with primary T1 BC as prior studies suggest therapeutic, diagnostic, and prognostic benefits. However, results on survival endpoints are sparse, conflicting, and often affected by various biases. To the best of our knowledge, the present population-wide study represents the largest cohort of patients diagnosed with T1 BC and provides real-world evidence supporting the utilisation of re-resection in

Published
2022

17. What happens to drug use and expenditure when cost sharing is completely removed? Evidence from a Canadian provincial public drug plan

Author

Laba T-L, Cheng L, Worthington HC, McGrail K, Chan FKI, Mamdani M, and Law MR

Subjects
Health Policy & Services, 1117 Public Health and Health Services, 1605 Policy and Administration
Abstract

Objectives The role of cost-sharing for medicines is under active policy discussion, including in proposals for value-based insurance design. To inform this debate, we estimated the impact of completely removing cost-sharing on medication use and expenditure using a quasi-experimental approach. Methods Fair PharmaCare, British Columbia’s income-based public drug plan, includes a household out-of-pocket limit. Therefore, when one household member starts a long-term high-cost drug surpassing this maximum, cost-sharing is completely removed for other family members. We used an interrupted time series design to estimate monthly prescriptions and expenditures of other household members, 24 months before and after cost-sharing removal. Results We studied 2191 household members newly free of cost-sharing requirements, most of whom had lower incomes. R emoving cost-sharing increased the level of drug expenditure and prescription numbers by 16 and 19%, respectively (i.e. $2659.43 (95%$1507.27–$3811.59, p < 0.001); 50.0 (95%CI 25.1–74.9, p < 0.001)) relative to prior expenditures and utilization without changing pre-existing trends. Much of this change was driven by 533 individuals initiating medication for the first time after cost-sharing removal. This initiation substantially increased average expenditure, especially for antiviral agents. Conclusions Completely removing cost-sharing, independent of health status, significantly increased medication use and expenditure particularly due to medicine initiation by new users. While costs may be preventing use, the appropriateness of additional use, especially among new users, is unclear.

Published
2020

18. A simplified (modified) Duke Activity Status Index (M-DASI) to characterise functional capacity: A secondary analysis of the Measurement of Exercise Tolerance before Surgery (METS) study

Author

Riedel, B., Li, M.H-G, Lee, C.H.A., Ismail, H., Cuthbertson, B.H., Wijeysundera, D.N., Ho, K.M., Wallace, S., Thompson, B., Ellis, M., Borg, B., Kerridge, R.K., Douglas, J., Brannan, J., Pretto, J., Godsall, M.G., Beauchamp, N., Allen, S., Kennedy, A., Wright, E., Malherbe, J., Melville, A., Sivakumar, H., Murmane, A., Kenchington, K., Kirabiyik, Y., Gurunathan, U., Stonell, C., Brunello, K., Steele, K., Tronstad, O., Masel, P., Dent, A., Smith, E., Bodger, A., Abolfathi, M., Sivalingam, P., Hall, A., Painter, T.W., Macklin, S., Elliott, A., Carrera, A.M., Terblanche, N.C.S., Pitt, S., Samuels, J., Wilde, C., Leslie, K., MacCormick, A., Bramley, D., Southcott, A.M., Grant, J., Taylor, H., Bates, S., Towns, M., Tippett, A., Marshall, F., Mazer, C.D., Kunasingam, J., Yagnik, A., Crescini, C., Yagnik, S., McCartney, C.J.L., Choi, S., Somascanthan, P., Flores, K., Au, S., Beattie, W.S., Karkouti, K., Clarke, H.A., Jerath, A., McCluskey, S.A., Wasowicz, M., Day, L., Pazmino-Canizares, J., Oh, P., Belliard, R., Lee, L., Dobson, K., Chan, V., Brull, R., Ami, N., Stanbrook, M., Hagen, K., Campbell, D., Short, T., Van Der Westhuizen, J., Higgie, J.K., Lindsay, H., Jang, R., Wong, C., Mcallister, D., Ali, M., Kumar, J., Waymouth, E., Kim, C., Dimech, J., Lorimer, M., Tai, J., Miller, R., Sara, R., Collingwood, A., Olliff, S., Gabriel, S., Houston, H., Dalley, P., Hurford, S., Hunt, A., Andrews, L., Navarra, L., Jason-Smith, A., Thompson, H., McMillan, N., Back, G., Lum, M., Martin, D., S James, S., Filipe, H., Pinto, M., Kynaston, S., Phull, M., Beilstein, C., Bodger, P., Everingham, K., Hu, Y., Niebrzegowska, E., Corriea, C., Creary, T., Januszewska, M., Ahmad, T., Whalley, J., Haslop, R., McNeil, J., Brown, A., MacDonald, N., Pakats, M., Greaves, K., Jhanji, S., Raobaikady, R., Black, E., Rooms, M., Lawrence, H., Koutra, M., Pirie, K., Gertsman, M., Jack, S., Celinski, M., Levett, D., Edwards, M., Salmon, K., Bolger, C., Loughney, L., Seaward, L., Collins, H., Tyrell, B., Tantony, N., Golder, K., Ackland, G.L., Stephens, R.C.M., Gallego-Paredes, L., Reyes, A., Gutierrez del Arroyo, A., Raj, A., Lifford, R., Melo, M., Mamdani, M., Hillis, G., Wijeysundera, H.C., Riedel, B., Li, M.H-G, Lee, C.H.A., Ismail, H., Cuthbertson, B.H., Wijeysundera, D.N., Ho, K.M., Wallace, S., Thompson, B., Ellis, M., Borg, B., Kerridge, R.K., Douglas, J., Brannan, J., Pretto, J., Godsall, M.G., Beauchamp, N., Allen, S., Kennedy, A., Wright, E., Malherbe, J., Melville, A., Sivakumar, H., Murmane, A., Kenchington, K., Kirabiyik, Y., Gurunathan, U., Stonell, C., Brunello, K., Steele, K., Tronstad, O., Masel, P., Dent, A., Smith, E., Bodger, A., Abolfathi, M., Sivalingam, P., Hall, A., Painter, T.W., Macklin, S., Elliott, A., Carrera, A.M., Terblanche, N.C.S., Pitt, S., Samuels, J., Wilde, C., Leslie, K., MacCormick, A., Bramley, D., Southcott, A.M., Grant, J., Taylor, H., Bates, S., Towns, M., Tippett, A., Marshall, F., Mazer, C.D., Kunasingam, J., Yagnik, A., Crescini, C., Yagnik, S., McCartney, C.J.L., Choi, S., Somascanthan, P., Flores, K., Au, S., Beattie, W.S., Karkouti, K., Clarke, H.A., Jerath, A., McCluskey, S.A., Wasowicz, M., Day, L., Pazmino-Canizares, J., Oh, P., Belliard, R., Lee, L., Dobson, K., Chan, V., Brull, R., Ami, N., Stanbrook, M., Hagen, K., Campbell, D., Short, T., Van Der Westhuizen, J., Higgie, J.K., Lindsay, H., Jang, R., Wong, C., Mcallister, D., Ali, M., Kumar, J., Waymouth, E., Kim, C., Dimech, J., Lorimer, M., Tai, J., Miller, R., Sara, R., Collingwood, A., Olliff, S., Gabriel, S., Houston, H., Dalley, P., Hurford, S., Hunt, A., Andrews, L., Navarra, L., Jason-Smith, A., Thompson, H., McMillan, N., Back, G., Lum, M., Martin, D., S James, S., Filipe, H., Pinto, M., Kynaston, S., Phull, M., Beilstein, C., Bodger, P., Everingham, K., Hu, Y., Niebrzegowska, E., Corriea, C., Creary, T., Januszewska, M., Ahmad, T., Whalley, J., Haslop, R., McNeil, J., Brown, A., MacDonald, N., Pakats, M., Greaves, K., Jhanji, S., Raobaikady, R., Black, E., Rooms, M., Lawrence, H., Koutra, M., Pirie, K., Gertsman, M., Jack, S., Celinski, M., Levett, D., Edwards, M., Salmon, K., Bolger, C., Loughney, L., Seaward, L., Collins, H., Tyrell, B., Tantony, N., Golder, K., Ackland, G.L., Stephens, R.C.M., Gallego-Paredes, L., Reyes, A., Gutierrez del Arroyo, A., Raj, A., Lifford, R., Melo, M., Mamdani, M., Hillis, G., and Wijeysundera, H.C.

Abstract

Background Accurate assessment of functional capacity, a predictor of postoperative morbidity and mortality, is essential to improving surgical planning and outcomes. We assessed if all 12 items of the Duke Activity Status Index (DASI) were equally important in reflecting exercise capacity. Methods In this secondary cross-sectional analysis of the international, multicentre Measurement of Exercise Tolerance before Surgery (METS) study, we assessed cardiopulmonary exercise testing and DASI data from 1455 participants. Multivariable regression analyses were used to revise the DASI model in predicting an anaerobic threshold (AT) >11 ml kg −1 min −1 and peak oxygen consumption (VO 2 peak) >16 ml kg −1 min −1, cut-points that represent a reduced risk of postoperative complications. Results Five questions were identified to have dominance in predicting AT>11 ml kg −1 min −1 and VO 2 peak>16 ml.kg −1min −1. These items were included in the M-DASI-5Q and retained utility in predicting AT>11 ml.kg −1.min −1 (area under the receiver-operating-characteristic [AUROC]-AT: M-DASI-5Q=0.67 vs original 12-question DASI=0.66) and VO 2 peak (AUROC-VO2 peak: M-DASI-5Q 0.73 vs original 12-question DASI 0.71). Conversely, in a sensitivity analysis we removed one potentially sensitive question related to the ability to have sexual relations, and the ability of the remaining four questions (M-DASI-4Q) to predict an adequate functional threshold remained no worse than the original 12-question DASI model. Adding a dynamic component to the M-DASI-4Q by assessing the chronotropic response to exercise improved its ability to discriminate between those with VO 2 peak>16 ml.kg −1.min −1 and VO 2 peak<16 ml.kg −1.min −1. Conclusions The M-DASI provides a simple screening tool for further preoperative evaluation, including with cardiopulmonary exercise testing, to guide perioperative management.

Published
2020

20. A simplified (modified) Duke Activity Status Index (M-DASI) to characterise functional capacity: a secondary analysis of the Measurement of Exercise Tolerance before Surgery (METS) study

Author

Riedel, Bernhard, primary, Li, Michael H-G., additional, Lee, C.H. Angus, additional, Ismail, Hilmy, additional, Cuthbertson, Brian H., additional, Wijeysundera, Duminda N., additional, Ho, Kwok M., additional, Wallace, S., additional, Thompson, B., additional, Ellis, M., additional, Borg, B., additional, Kerridge, R.K., additional, Douglas, J., additional, Brannan, J., additional, Pretto, J., additional, Godsall, M.G., additional, Beauchamp, N., additional, Allen, S., additional, Kennedy, A., additional, Wright, E., additional, Malherbe, J., additional, Ismail, H., additional, Riedel, B., additional, Melville, A., additional, Sivakumar, H., additional, Murmane, A., additional, Kenchington, K., additional, Kirabiyik, Y., additional, Gurunathan, U., additional, Stonell, C., additional, Brunello, K., additional, Steele, K., additional, Tronstad, O., additional, Masel, P., additional, Dent, A., additional, Smith, E., additional, Bodger, A., additional, Abolfathi, M., additional, Sivalingam, P., additional, Hall, A., additional, Painter, T.W., additional, Macklin, S., additional, Elliott, A., additional, Carrera, A.M., additional, Terblanche, N.C.S., additional, Pitt, S., additional, Samuels, J., additional, Wilde, C., additional, Leslie, K., additional, MacCormick, A., additional, Bramley, D., additional, Southcott, A.M., additional, Grant, J., additional, Taylor, H., additional, Bates, S., additional, Towns, M., additional, Tippett, A., additional, Marshall, F., additional, Mazer, C.D., additional, Kunasingam, J., additional, Yagnik, A., additional, Crescini, C., additional, Yagnik, S., additional, McCartney, C.J.L., additional, Choi, S., additional, Somascanthan, P., additional, Flores, K., additional, Au, S., additional, Beattie, W.S., additional, Karkouti, K., additional, Clarke, H.A., additional, Jerath, A., additional, McCluskey, S.A., additional, Wasowicz, M., additional, Day, L., additional, Pazmino-Canizares, J., additional, Oh, P., additional, Belliard, R., additional, Lee, L., additional, Dobson, K., additional, Chan, V., additional, Brull, R., additional, Ami, N., additional, Stanbrook, M., additional, Hagen, K., additional, Campbell, D., additional, Short, T., additional, Van Der Westhuizen, J., additional, Higgie, J.K., additional, Lindsay, H., additional, Jang, R., additional, Wong, C., additional, Mcallister, D., additional, Ali, M., additional, Kumar, J., additional, Waymouth, E., additional, Kim, C., additional, Dimech, J., additional, Lorimer, M., additional, Tai, J., additional, Miller, R., additional, Sara, R., additional, Collingwood, A., additional, Olliff, S., additional, Gabriel, S., additional, Houston, H., additional, Dalley, P., additional, Hurford, S., additional, Hunt, A., additional, Andrews, L., additional, Navarra, L., additional, Jason-Smith, A., additional, Thompson, H., additional, McMillan, N., additional, Back, G., additional, Lum, M., additional, Martin, D., additional, S James, S., additional, Filipe, H., additional, Pinto, M., additional, Kynaston, S., additional, Phull, M., additional, Beilstein, C., additional, Bodger, P., additional, Everingham, K., additional, Hu, Y., additional, Niebrzegowska, E., additional, Corriea, C., additional, Creary, T., additional, Januszewska, M., additional, Ahmad, T., additional, Whalley, J., additional, Haslop, R., additional, McNeil, J., additional, Brown, A., additional, MacDonald, N., additional, Pakats, M., additional, Greaves, K., additional, Jhanji, S., additional, Raobaikady, R., additional, Black, E., additional, Rooms, M., additional, Lawrence, H., additional, Koutra, M., additional, Pirie, K., additional, Gertsman, M., additional, Jack, S., additional, Celinski, M., additional, Levett, D., additional, Edwards, M., additional, Salmon, K., additional, Bolger, C., additional, Loughney, L., additional, Seaward, L., additional, Collins, H., additional, Tyrell, B., additional, Tantony, N., additional, Golder, K., additional, Ackland, G.L., additional, Stephens, R.C.M., additional, Gallego-Paredes, L., additional, Reyes, A., additional, Gutierrez del Arroyo, A., additional, Raj, A., additional, R Lifford, R., additional, Melo, M., additional, Mamdani, M., additional, Hillis, G., additional, and Wijeysundera, H.C., additional

Published
2021
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33. Predictors of re-resection in primary T1 bladder cancer: Identifying patients who do not receive guideline-concordant care at the population level

Author

Wettstein, M.S., primary, Baxter, N.N., additional, Sutradhar, R., additional, Mamdani, M., additional, Pham, S., additional, Qadri, S.R., additional, Bhalla, G., additional, Li, K., additional, Liu, N., additional, Van Der Kwast, T., additional, Hermanns, T., additional, and Kulkarni, G.S., additional

Published
2020
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35. Integration of the Duke Activity Status Index into preoperative risk evaluation: a multicentre prospective cohort study

Author

Wijeysundera, Duminda N., primary, Beattie, W. Scott, additional, Hillis, Graham S., additional, Abbott, Tom E.F., additional, Shulman, Mark A., additional, Ackland, Gareth L., additional, Mazer, C. David, additional, Myles, Paul S., additional, Pearse, Rupert M., additional, Cuthbertson, Brian H., additional, Myles, P.S., additional, Shulman, M.A., additional, Wallace, S., additional, Farrington, C., additional, Thompson, B., additional, Ellis, M., additional, Borg, B., additional, Kerridge, R.K., additional, Douglas, J., additional, Brannan, J., additional, Pretto, J., additional, Godsall, M.G., additional, Beauchamp, N., additional, Allen, S., additional, Kennedy, A., additional, Wright, E., additional, Malherbe, J., additional, Ismail, H., additional, Riedel, B., additional, Melville, A., additional, Sivakumar, H., additional, Murmane, A., additional, Kenchington, K., additional, Kirabiyik, Y., additional, Gurunathan, U., additional, Stonell, C., additional, Brunello, K., additional, Steele, K., additional, Tronstad, O., additional, Masel, P., additional, Dent, A., additional, Smith, E., additional, Bodger, A., additional, Abolfathi, M., additional, Sivalingam, P., additional, Hall, A., additional, Painter, T.W., additional, Macklin, S., additional, Elliott, A., additional, Carrera, A.M., additional, Terblanche, N.C.S., additional, Pitt, S., additional, Samuels, J., additional, Wilde, C., additional, Leslie, K., additional, MacCormick, A., additional, Bramley, D., additional, Southcott, A.M., additional, Grant, J., additional, Taylor, H., additional, Bates, S., additional, Towns, M., additional, Tippett, A., additional, Marshall, F., additional, Mazer, C.D., additional, Kunasingam, J., additional, Yagnik, A., additional, Crescini, C., additional, Yagnik, S., additional, McCartney, C.J.L., additional, Choi, S., additional, Somascanthan, P., additional, Flores, K., additional, Wijeysundera, D.N., additional, Beattie, W.S., additional, Karkouti, K., additional, Clarke, H.A., additional, Jerath, A., additional, McCluskey, S.A., additional, Wasowicz, M., additional, Granton, J.T., additional, Day, L., additional, Pazmino-Canizares, J., additional, Oh, P., additional, Belliard, R., additional, Lee, L., additional, Dobson, K., additional, Chan, V., additional, Brull, R., additional, Ami, N., additional, Stanbrook, M., additional, Hagen, K., additional, Campbell, D., additional, Short, T., additional, Van Der Westhuizen, J., additional, Higgie, K., additional, Lindsay, H., additional, Jang, R., additional, Wong, C., additional, Mcallister, D., additional, Ali, M., additional, Kumar, J., additional, Waymouth, E., additional, Kim, C., additional, Dimech, J., additional, Lorimer, M., additional, Tai, J., additional, Miller, R., additional, Sara, R., additional, Collingwood, A., additional, Olliff, S., additional, Gabriel, S., additional, Houston, H., additional, Dalley, P., additional, Hurford, S., additional, Hunt, A., additional, Andrews, L., additional, Navarra, L., additional, Jason-Smith, A., additional, Thompson, H., additional, McMillan, N., additional, Back, G., additional, Croal, B.L., additional, Lum, M., additional, Martin, D., additional, James, S., additional, Filipe, H., additional, Pinto, M., additional, Kynaston, S., additional, Pearse, R.M., additional, Abbott, T.E.F., additional, Phull, M., additional, Beilstein, C., additional, Bodger, P., additional, Everingham, K., additional, Hu, Y., additional, Niebrzegowska, E., additional, Corriea, C., additional, Creary, T., additional, Januszewska, M., additional, Ahmad, T., additional, Whalley, J., additional, Haslop, R., additional, McNeil, J., additional, Brown, A., additional, MacDonald, N., additional, Pakats, M., additional, Greaves, K., additional, Jhanji, S., additional, Raobaikady, R., additional, Black, E., additional, Rooms, M., additional, Lawrence, H., additional, Koutra, M., additional, Pirie, K., additional, Gertsman, M., additional, Jack, S., additional, Celinski, M., additional, Levett, D., additional, Edwards, M., additional, Salmon, K., additional, Bolger, C., additional, Loughney, L., additional, Seaward, L., additional, Collins, H., additional, Tyrell, B., additional, Tantony, N., additional, Golder, K., additional, Ackland, G.L., additional, Stephens, R.C.M., additional, Gallego-Paredes, L., additional, Reyes, A., additional, Gutierrez del Arroyo, A., additional, Raj, A., additional, Lifford, R., additional, Cuthbertson, B.H., additional, Torres, E., additional, Ambosta, A., additional, Melo, M., additional, Mamdani, M., additional, Thorpe, K.E., additional, Grocott, M.P.W., additional, Hillis, G., additional, and Wijeysundera, H.C., additional

Published
2020
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37. INTRODUCTION

Author

Muscedere, John, Bebenek, Sarah Grace, Stockley, Denise, Kinderman, Laura, Barrie, Carol, Salim, S., Warkentin, L., Gallivan, A., Churchill, T., Baracos, V., Khadaroo, R., McCullough, J., Keller, H., Vesnaver, E., Marcus, H., Lister, T., Nasser, R., Belley, L., Laur, C., Gainer, R., Moorhouse, P., Mallery, L., Hirsch, G., Hamilton, G., Wheeler, K., Di Michelle, J., Lalu, M.M, McIsaac, D. I, Mallery, K., Theou, O., Goldstein, J., Armstrong, J., Webb, J., Greene, J., Doyle, E., Douglas, B., Lee, J., Rockwood, K., Whitty, R., Koo, E., Porter, S., Battu, K., Kalocsai, C., Reid, J., Kho, M., Molloy, A., Herridge, M. S, Karachi, T., Fox-Robichaud, A., Koo, K. KY, Lo, V., Mathur, S., McCaughan, M., Pellizzari, J., Rudkowski, J., Figueiredo, S., Morais, J., Mayo, N., Meffen, K., Penner, C., Meyyappan, R., Sandoval, R., Broderick, J., Hoffer, A., Chambers, S., Ball, I., Martin, C., Awan, S., Rajji, T., Uranis, C., Kim, D., Burhan, A., Ting, R., Ito, H., Graff, A., Gerretsen, P., Woo, V., Mulsant, B., Davies, S., Paul, L. Read, Spice, R., Sinnarajah, A., Ho, G., Webb, M., Uniacke, J., Linsey, J., Kettle, J., Salmon, C., Mohammed, R., Whitby, C., Cowie, B., Wang, S., Sawatzky, R., Chan, E., Wolfs, D., Harding, W., Laforest, E., Schick-Makaroff, K., King, G., Cohen, S. R., Neufeld, C., Lett, J., Voth, J., Durepos, P., Wickson-Griffiths, A., Hazzan, A. Abiola, Kaasalainen, S., Vastis, V., Battistella, L., Papaioannou, A., Asselin, G., Klein, D., Tan, A., Kendell, C., Burge, F., Kotecha, J., Marshall, E., Cash, C., Tschupruk, C., Urquhart, R., Cottrell, L., Erbacker, L., Pesut, B., Duggleby, W., Bui, M., Te, A., Brazil, E., Sussman, T., Team, SPA-LTC, Delicaet, K., MacDonald, J., Hartwick, M., des Ordons, A. Roze, Myers, J., Pereira, J., Simon, J., Abdul-Razzak, A., Sharma, A., Ogilvie, L., Downar, J., Choukou, M.A., Holroyd-Leduc, J. M., Kazanjian, A., Durand, P. J, Straus, S. E, Légaré, F., Turgeon, A. F., Tourigny, A., Dumont, S., Mc Giguere, A., Lounsbury, K., Friesen, D., Bitschy, A., Donald, E. E, Stajduhar, K., Knapp, A., Klinger, C., Wentlandt, K., Urowitz, S., Walton, T., Chahal, M., Zwicker, V., Cohen, T., Morales, M. López, Miller, K., Duggan, K., Barnett-Cowan, M., Kortes-Miller, K., Kelley, M. Lou, Nayfeh, A., Marcoux, I., Jutai, J., Virag, O., Khakoo, A., Incardona, N., Workentin, K., Maxwell, C., Stock, K., Hogan, D. B., Tyas, S. L., Bronskill, S. E., Morris, A. M., Bell, C. M., Jeffs, L., Gandhi, S., Blain, J., Toubasi, S., Andrew, M., Ashe, M., Atkinson, E., Ayala, A. P., Bergman, H., Ploeg, J., McGilton, K., Patten, S. B., Maxwell, C. J., Delleman, B., Chan, D., Siu, H., Howard, M., Mangin, D., Akioyamen, L., Hoben, M., Estabrooks, C., McArthur, C., Gibbs, J. C., Patel, R., Neves, P., Killingbeck, J., Hirdes, J., Milligan, J., Berg, K., Giangreogrio, L., Adekpedjou, R., Stacey, D., Brière, N., Freitas, A., Marjolein, M., Garvelink, Turcotte, S., Heyer, M., Boscart, V., Heckman, G., Zahradnik, M., Jeffs, L. P., Mainville, C., Maione, M., Morris, A., Bell, C., Bronskill, S., Tscheng, D., Sever, L., Hyland, S., Emond, J., Garvelink, M., Menear, M., MacLeod, T., LeBlanc, C., Allen, M., McLean-Veysey, P., Rodney-Cail, N., Steeves, B., Bezanson, E., Van Ooteghem, K., Trinh, A., Cowan, D., Kwok, L., Fels, D., Meza, M., Fels-Leung, S., Ouellette-Kuntz, H., McKenzie, K., Martin, L., Bark, D., Hanafi, S., Gibson, W., Wagg, A., Tanel, M., Laing, A., Weaver, T., Lupo, J., Giangregorio, L., Payne, A., Sheets, D., Beach, C., Elliott, J., Stolee, P., Stinchcombe, A., Bédard, M., Enright, J., Wilson, K., Ozen, L., Silman, J., Gibbons, C., McKinnon, T., Timble, J., Willison, K., Boland, L., Perez, M. Margarita Becerra, McIsaac, D., Edmond, J., Brown, K., Leigh, J. Parsons, Buchner, D., Stelfox, H. T., Aziz, J., Crake, D., Ren, Z., Grant, T., Goubran, R., Knoefel, F., Sveistrup, H., Bilodeau, M., Oliver, J., Chidwick, P., Booi, L., Magyar, T., Martin, M., Ko, J. Hyun, Shannon, J., Wilson-Pease, E., Kephart, G., Babin, N., Malik, H., Maximos, M., Seng, S., Vandenberg, G., Dal Bello-Haas, V., Lagrotteria, A., Sullivan, K., Mihaylova, A., Lu, C., Koh, J., Hamielec, C., Steer, M., Jimenez, C., Woo, K., Julian, P., Martin, L. Schindel, McLelland, V., Ryan, D., Wilding, L., Chang, C. E., van Schooten, K. S, Wong, F., Robinovitch, S. N, Balasubramanaiam, B., Chenkin, J., Snider, T. G., Melady, D., Lee, J. S., Petrella, A., Heath, M., Shellington, E., Laguë, A., Voyer, P., Ouellet, M., Boucher, V., Pelletier, M., Gouin, É., Daoust, R., Berthelot, S., Giroux, M., Sirois, M., Émond, M., Bergstrom, V., Tate, K., Lee, S., Reid, C., Rowe, B., Cummings, G., Holroyd-Leduc, J., El-Bialy, R., Zhao, B., Baumbusch, J., Busson, C., Kohr, R., Donovan, J., Philpott, K., Kingston, J., Rickards, T., Weiler, C., Lanovaz, J., Arnold, C., Chiu, K., Cuperfain, A., Zhu, K., Zhao, X., Zhao, S., Iaboni, A., Perrella, A., Chau, V., Hu, C. Dong, Farooqi, M., Patel, S., Bauer, J., Lee, L., Schill, C., Patel, T., Mroz, L., Kryworuchko, J., Carter, R., Spencer, L., Barwich, D., Roy, N., Després, C., Leyenaar, M., McLeod, B., Poss, J., Costa, A., Blums, J., Costa, I. Geraldina, Tregunno, D., Kirkham, J., Seitz, D., Velkers, C., Krawczyk, M., Garland, E., Michaud, M., Pakzad, S., Bourque, P. E., Eamer, G., Gibson, J. A, Gillis, C., Hsu, A. T, MacDonald, E., Whitlock, R., Khadaroo, R. G, Brisebois, R., Clement, F., Hathaway, J., Bagheri, Z. S., Costa, I. G., Schinkel-Ivy, A., Rodney, P. (Paddy), Varcoe, C., Jiwani, B., Fenton, T., Gramlich, L., Tangri, N., Eng, F., Bohm, C., Komenda, P., Rigatto, C., Brar, R., McCloskey, R., Keeping-Burke, L., Donovan, C., Verma, A., Razak, F., Kwan, J., Lapointe-Shaw, L., Rawal, S., Tang, T., Weinerman, A., Guo, Y., Mamdani, M., McNicholl, T., Valaitis, R., Tarraf, R., Boakye, O., Suter, E., Boulanger, P., Birney, A., Sadowski, C. A, Gill, G., Mrklas, K., Plaisance, A., Noiseux, F., Francois, R., LeBlanc, A., McGinn, C. A., Tapp, D., Archambault, P. M., Begum, J., Wikjord, N., Roy, P., Reimer-Kirkham, S., Doane, G., Hilliard, N., Giesbrech, M., Dujela, C., Harerimana, B., Forchuk, C., Booth, R., Vasudev, A., Isaranuwatchai, W., Seth, P., Ramsey, D., Rudnick, A., Heisel, M., Reiss, J., Lee, E., Mate, K., Aubertin-Leheude, M., Fiore, J., Auais, M., Moriello, C., Scott, S., Wilson, M., McDonald, E., Lee, T., Arora, N., Hanvey, L., Elston, D., Heyland, R., Heyland, D., Langevin, J., Fang, Q., Price, D., Nowak, C., Fang, H., Richardson, J., Phillips, S., Gordon, C., Xie, F., Adachi, J., Tang, A., Swinton, M., Winhall, M., Clark, B., Sinuff, T., Abelson, J., You, J., Shears, M., Takaoka, A., Tina, M., Amanda, H., Surenthar, T., Li, G., Rochwerg, B., Woo, T., Bagshaw, S., Johnstone, J., Cook, D., Beaton, D., Drance, E., Leblanc, M.E., O’Connor, D., Ono, E., Phinney, A., Reid, R. C., Rodney, P. A., Tait, J., Ward-Griffin, C., Millen, T., Clarke, F., Thabane, L., Dogba, M. J., Rivest, L.l, Durand, P. J., Fraser, K., Bourassa, H., Embuldeniya, G., Farmanova, E., Auguste, D., Witteman, H. O, Kröger, E., Beaulieu, É., MC Giguere, A., Paragg, J., Swindle, J., Webber, T., Porterfield, P., Husband, A., Kryworucko, J., Trenaman, L., Bryan, S., Cuthbertson, L., Bansback, N., de Grood, C., Dodek, P., Fowler, R., Forster, A., Boyd, J., Stelfox, H., Kruger, S., Steinberg, M., Quinn, K., Yarnell, C., Fu, L., Manuel, D., Tanuseputro, P., Stukel, T., Pinto, R., Scales, D., Laupacis, A., Varughese, R., Huang, A., Famure, O., Chowdhury, N., Renner, E., Kim, J., MacIver, J., Singer, L., Gali, B., Brewster, P., Asche, C., Mitz, A., Hundza, S., MacDonald, S., Kaechele, N., Donald, E., Kaur, S., Fernandes, P., Pauloff, K., Gordon, A., Kallan, L., Grinman, M., Human, T., Ying, I., Pattullo, A., Wong, H., Feldman, S., Moffat, D., Zjadewicz, K., McIntosh, C. J., Alghamdi, M., McComb, A., Ferrone, A., Geng, W., Weeks-Levy, C., and Menon, C.

Subjects
Abstracts, Canadian Frailty Network Abstracts from the Meeting in Toronto, September 27–29, 2015, Canadian Frailty Network Abstracts from the Meeting Held in Toronto, April 23–24, 2017
Published
2017

42. Impact of a household-level deductible on prescription drug use among lower-income adults: a quasi-experimental study.

Author

Law, MR, Cheng, L, Worthington, H, Majumdar, SR, McGrail, KM, Chan, F, Laba, T-L, Mamdani, M, Law, MR, Cheng, L, Worthington, H, Majumdar, SR, McGrail, KM, Chan, F, Laba, T-L, and Mamdani, M

Abstract

BACKGROUND: Several Canadian public drug plans have income-based deductibles, but we have limited data on their impact, particularly for vulnerable populations. Therefore, we studied the impact of deductibles in British Columbia's Fair PharmaCare program on drug use among lower-income adults. METHODS: We used a quasi-experimental regression discontinuity design to study the impact of BC rules that impose no deductible before receiving public coverage on households with incomes less than $15 000, a deductible of 2% of household income on those with incomes between $15 000 and $30 000, and a deductible of 3% of household income on those with incomes above $30 000. We studied the impact of these thresholds on public and total drug expenditures between 2003 and 2015 using 24 million person-years of data. RESULTS: Both thresholds decreased the proportion of beneficiaries receiving benefits, by 0.33 (95% confidence interval [CI] -0.34 to -0.30) and 0.05 (95% CI -0.064 to -0.032) respectively. There were also substantial reductions in the extent of public drug plan expenditures ($59.94 [95% CI -74.74 to -45.14] and $26.12 [95% CI -39.78 to -12.46], respectively). The change at the $15 000 threshold reduced patient drug expenditures by $26.00 (95% CI -45.48 to -6.51), or 7.2%. In contrast, we found no statistically significant change in total expenditures when households moved from a deductible of 2% to 3% at the $30 000 threshold. INTERPRETATION: Income-based deductibles considerably affected the extent of public subsidy for prescription drugs. For lower-income households making around $15 000, the deductible led to a reduction of 7.2% in overall drug use and costs. Although deductibles are a useful tool to limit public expenditures, policy-makers should be cautious in their use among vulnerable populations.

Published
2019

43. Screening for obstructive sleep apnea in stroke and tia patients using a portable sleep monitor: a randomized controlled trial

Author

Boulos, M., primary, Kamra, M., additional, Kirollos, N., additional, Colelli, D., additional, Gladstone, D., additional, Boyle, K., additional, Sundaram, A., additional, Hopyan, J., additional, Swartz, R., additional, Mamdani, M., additional, Isaranuwatchai, W., additional, Thorpe, K., additional, and Murray, B., additional

Published
2019
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44. Association of preoperative anaemia with cardiopulmonary exercise capacity and postoperative outcomes in noncardiac surgery: a substudy of the Measurement of Exercise Tolerance before Surgery (METS) Study

Author

Bartoszko, J., primary, Thorpe, K.E., additional, Laupacis, A., additional, Wijeysundera, D.N., additional, Myles, P.S., additional, Shulman, M.A., additional, Wallace, S., additional, Farrington, C., additional, Thompson, B., additional, Ellis, M., additional, Borg, B., additional, Kerridge, R.K., additional, Douglas, J., additional, Brannan, J., additional, Pretto, J., additional, Godsall, M.G., additional, Beauchamp, N., additional, Allen, S., additional, Kennedy, A., additional, Wright, E., additional, Malherbe, J., additional, Ismail, H., additional, Riedel, B., additional, Melville, A., additional, Sivakumar, H., additional, Murmane, A., additional, Kenchington, K., additional, Kirabiyik, Y., additional, Gurunathan, U., additional, Stonell, C., additional, Brunello, K., additional, Steele, K., additional, Tronstad, O., additional, Masel, P., additional, Dent, A., additional, Smith, E., additional, Bodger, A., additional, Abolfathi, M., additional, Sivalingam, P., additional, Hall, A., additional, Painter, T.W., additional, Macklin, S., additional, Elliott, A., additional, Carrera, A.M., additional, Terblanche, N.C.S., additional, Pitt, S., additional, Samuels, J., additional, Wilde, C., additional, Leslie, K., additional, MacCormick, A., additional, Bramley, D., additional, Southcott, A.M., additional, Grant, J., additional, Taylor, H., additional, Bates, S., additional, Towns, M., additional, Tippett, A., additional, Marshall, F., additional, Mazer, C.D., additional, Kunasingam, J., additional, Yagnik, A., additional, Crescini, C., additional, Yagnik, S., additional, McCartney, C.J.L., additional, Choi, S., additional, Somascanthan, P., additional, Flores, K., additional, Beattie, W.S., additional, Karkouti, K., additional, Clarke, H.A., additional, Jerath, A., additional, McCluskey, S.A., additional, Wasowicz, M., additional, Granton, J.T., additional, Day, L., additional, Pazmino-Canizares, J., additional, Oh, P., additional, Belliard, R., additional, Lee, L., additional, Dobson, K., additional, Chan, V., additional, Brull, R., additional, Ami, N., additional, Stanbrook, M., additional, Hagen, K., additional, Campbell, D., additional, Short, T., additional, Van Der Westhuizen, J., additional, Higgie, K., additional, Lindsay, H., additional, Jang, R., additional, Wong, C., additional, Mcallister, D., additional, Ali, M., additional, Kumar, J., additional, Waymouth, E., additional, Kim, C., additional, Dimech, J., additional, Lorimer, M., additional, Tai, J., additional, Miller, R., additional, Sara, R., additional, Collingwood, A., additional, Olliff, S., additional, Gabriel, S., additional, Houston, H., additional, Dalley, P., additional, Hurford, S., additional, Hunt, A., additional, Andrews, L., additional, Navarra, L., additional, Jason-Smith, A., additional, Thompson, H., additional, McMillan, N., additional, Back, G., additional, Croal, B.L., additional, Lum, M., additional, Martin, D., additional, James, S., additional, Filipe, H., additional, Pinto, M., additional, Kynaston, S., additional, Pearse, R.M., additional, Abbott, T.E.F., additional, Phull, M., additional, Beilstein, C., additional, Bodger, P., additional, Everingham, K., additional, Hu, Y., additional, Niebrzegowska, E., additional, Corriea, C., additional, Creary, T., additional, Januszewska, M., additional, Ahmad, T., additional, Whalley, J., additional, Haslop, R., additional, McNeil, J., additional, Brown, A., additional, MacDonald, N., additional, Pakats, M., additional, Greaves, K., additional, Jhanji, S., additional, Raobaikady, R., additional, Black, E., additional, Rooms, M., additional, Lawrence, H., additional, Koutra, M., additional, Pirie, K., additional, Gertsman, M., additional, Jack, S., additional, Celinski, M., additional, Levett, D., additional, Edwards, M., additional, Salmon, K., additional, Bolger, C., additional, Loughney, L., additional, Seaward, L., additional, Collins, H., additional, Tyrell, B., additional, Tantony, N., additional, Golder, K., additional, Ackland, G.L., additional, Gallego-Paredes, L., additional, Reyes, A., additional, Gutierrez del Arroyo, A., additional, Raj, A., additional, Lifford, R., additional, Cuthbertson, B.H., additional, Torres, E., additional, Ambosta, A., additional, Melo, M., additional, Mamdani, M., additional, Grocott, M.P.W., additional, Hillis, G., additional, and Wijeysundera, H.C., additional

Published
2019
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47. Using the 6-minute walk test to predict disability-free survival after major surgery

Author

Shulman, M.A., primary, Cuthbertson, B.H., additional, Wijeysundera, D.N., additional, Pearse, R.M., additional, Thompson, B., additional, Torres, E., additional, Ambosta, A., additional, Wallace, S., additional, Farrington, C., additional, Myles, P.S., additional, Ellis, M., additional, Borg, B., additional, Kerridge, R.K., additional, Douglas, J., additional, Brannan, J., additional, Pretto, J., additional, Godsall, M.G., additional, Beauchamp, N., additional, Allen, S., additional, Kennedy, A., additional, Wright, E., additional, Malherbe, J., additional, Ismail, H., additional, Riedel, B., additional, Melville, A., additional, Sivakumar, H., additional, Murmane, A., additional, Kenchington, K., additional, Gurunathan, U., additional, Stonell, C., additional, Brunello, K., additional, Steele, K., additional, Tronstad, O., additional, Masel, P., additional, Dent, A., additional, Smith, E., additional, Bodger, A., additional, Abolfathi, M., additional, Sivalingam, P., additional, Hall, A., additional, Painter, T., additional, Macklin, S., additional, Elliott, A., additional, Carrera, A.M., additional, Terblanche, N.C.S., additional, Pitt, S., additional, Samuels, J., additional, Wilde, C., additional, MacCormick, A., additional, Leslie, K., additional, Bramley, D., additional, Southcott, A.M., additional, Grant, J., additional, Taylor, H., additional, Bates, S., additional, Towns, M., additional, Tippett, A., additional, Marshall, F., additional, McCartney, C.J.L., additional, Choi, S., additional, Somascanthan, P., additional, Flores, K., additional, Beattie, W.S., additional, Karkouti, K., additional, Clarke, H.A., additional, Jerath, A., additional, McCluskey, S.A., additional, Wasowicz, M., additional, Granton, J.T., additional, Day, L., additional, Pazmino-Canizares, J., additional, Hagen, K., additional, Campbell, D., additional, Short, T., additional, Van Der Westhuizen, J., additional, Higgie, K., additional, Lindsay, H., additional, Jang, R., additional, Wong, C., additional, Mcallister, D., additional, Ali, M., additional, Kumar, J., additional, Waymouth, E., additional, Kim, C., additional, Dimech, J., additional, Lorimer, M., additional, Tai, J., additional, Miller, R., additional, Sara, R., additional, Collingwood, A., additional, Olliff, S., additional, Gabriel, S., additional, Houston, H., additional, Dalley, P., additional, Hurford, S., additional, Hunt, A., additional, Andrews, L., additional, Navarra, L., additional, Jason-Smith, A., additional, Thompson, H., additional, McMillan, N., additional, Back, G., additional, Melo, M., additional, Mamdani, M., additional, Hillis, G., additional, and Wijeysundera, H.C., additional

Published
2019
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48. Development and validation of outcome prediction models for aneurysmal subarachnoid haemorrhage: The SAHIT multinational cohort study

Author

Jaja, B.N.R. (Blessing), Saposnik, G. (Gustavo), Lingsma, H.F. (Hester), Macdonald, E. (Erin), Thorpe, K.E. (Kevin E.), Mamdani, M. (Muhammed), Steyerberg, E.W. (Ewout), Molyneux, A.J. (Andrew), Manoel, A.L.D.O. (Airton Leonardo De Oliveira), Schatlo, B. (Bawarjan), Hanggi, D. (Daniel), Hasan, D. (David), Wong, G.K.C. (George K.C.), Etminan, N. (Nima), Fukuda, H. (Hitoshi), Torner, J. (James), Schaller, K.L. (Karl L.), Suarez, J.I. (Jose I.), Stienen, M.N. (Martin N.), Vergouwen, M.D.I. (Mervyn D. I.), Rinkel, G.J.E. (Gabriel J.E.), Spears, J. (Julian), Cusimano, M.D. (Michael D.), Todd, M. (Michael), Le Roux, P. (Peter), Kirkpatrick, P. (Peter), Pickard, J. (John), Van Den Bergh, H. (Huub), Murray, G. (Gordon), Johnston, S.C. (S Claiborne), Yamagata, S. (Sen), Mayer, S. (Stephan), Schweizer, T.A. (Tom A.), Macdonald, R.L. (R. Loch), Jaja, B.N.R. (Blessing), Saposnik, G. (Gustavo), Lingsma, H.F. (Hester), Macdonald, E. (Erin), Thorpe, K.E. (Kevin E.), Mamdani, M. (Muhammed), Steyerberg, E.W. (Ewout), Molyneux, A.J. (Andrew), Manoel, A.L.D.O. (Airton Leonardo De Oliveira), Schatlo, B. (Bawarjan), Hanggi, D. (Daniel), Hasan, D. (David), Wong, G.K.C. (George K.C.), Etminan, N. (Nima), Fukuda, H. (Hitoshi), Torner, J. (James), Schaller, K.L. (Karl L.), Suarez, J.I. (Jose I.), Stienen, M.N. (Martin N.), Vergouwen, M.D.I. (Mervyn D. I.), Rinkel, G.J.E. (Gabriel J.E.), Spears, J. (Julian), Cusimano, M.D. (Michael D.), Todd, M. (Michael), Le Roux, P. (Peter), Kirkpatrick, P. (Peter), Pickard, J. (John), Van Den Bergh, H. (Huub), Murray, G. (Gordon), Johnston, S.C. (S Claiborne), Yamagata, S. (Sen), Mayer, S. (Stephan), Schweizer, T.A. (Tom A.), and Macdonald, R.L. (R. Loch)

Abstract

Objective To develop and validate a set of practical prediction tools that reliably estimate the outcome of subarachnoid haemorrhage from ruptured intracranial aneurysms (SAH). Design Cohort study with logistic regression analysis to combine predictors and treatment modality. Setting Subarachnoid Haemorrhage International Trialists' (SAHIT) data repository, including randomised clinical trials, prospective observational studies, and hospital registries. Participants Researchers collaborated to pool dataset

Published
2018
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49. Development and validation of outcome prediction models for aneurysmal subarachnoid haemorrhage: the SAHIT multinational cohort study

Author

Jaja, BNR, Saposnik, G, Lingsma, Hester, Macdonald, E, Thorpe, KE, Mamdani, M, Steyerberg, Ewout, Molyneux, A, Manoel, ALD, Schatlo, B, Hanggi, D, Hasan, D, Wong, GKC, Etminan, N, Fukuda, H, Torner, J, Schaller, KL, Suarez, JI, Stienen, MN, Vergouwen, MDI, Rinkel, GJE, Spears, J, Cusimano, MD, Todd, M, le Roux, P, Kirkpatrick, P, Pickard, J, Bergh, WM, Murray, G, Johnston, SC, Yamagata, S, Mayer, S, Schweizer, TA, Macdonald, RL, Jaja, BNR, Saposnik, G, Lingsma, Hester, Macdonald, E, Thorpe, KE, Mamdani, M, Steyerberg, Ewout, Molyneux, A, Manoel, ALD, Schatlo, B, Hanggi, D, Hasan, D, Wong, GKC, Etminan, N, Fukuda, H, Torner, J, Schaller, KL, Suarez, JI, Stienen, MN, Vergouwen, MDI, Rinkel, GJE, Spears, J, Cusimano, MD, Todd, M, le Roux, P, Kirkpatrick, P, Pickard, J, Bergh, WM, Murray, G, Johnston, SC, Yamagata, S, Mayer, S, Schweizer, TA, and Macdonald, RL

Published
2018

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