338 results on '"Malthouse, J."'
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2. Quantifying tetrahedral adduct formation and stabilization in the cysteine and the serine proteases
3. Mechanism of the binding of Z–L-tryptophan and Z–L-phenylalanine to thermolysin and stromelysin-1 in aqueous solutions
4. pH stability of the stromelysin-1 catalytic domain and its mechanism of interaction with a glyoxal inhibitor
5. Conformational, receptor interaction and alanine scan studies of glucose-dependent insulinotropic polypeptide
6. Oxyanion and tetrahedral intermediate stabilisation by subtilisin: Detection of a new tetrahedral adduct
7. Biotransformation of halophenols using crude cell extracts of Pseudomonas putida F6
8. 13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and γ-glutamyl cycle activity in a clonal pancreatic beta-cell line
9. Effect of acute dietary standardization on the urinary, plasma, and salivary metabolomic profiles of healthy humans
10. Impact of the gliotoxin l-serine- O-sulphate on cellular metabolism in cultured rat astrocytes
11. Synthesis of 2-guanidinyl pyridines and their trypsin inhibition and docking
12. Correction to Kinetic Study of the Effect of pH on the Trypsin-Catalyzed Hydrolysis of N-α-benzyloxycarbonyl-l-lysine-p-nitroanilide: Mechanism of Trypsin Catalysis
13. Kinetic Studies of the Effect of pH on the Trypsin-Catalyzed Hydrolysis of N-α-benzyloxycarbonyl-l-lysine-p-nitroanilide: Mechanism of Trypsin Catalysis
14. The Influence of Environment on Thiol Group Reactivity
15. 13C NMR study of how the oxyanion pKa values of subtilisin and chymotrypsin tetrahedral adducts are affected by different amino acid residues binding in enzyme substitutes S1-S4
16. Ionisations within a subtilisin–glyoxal inhibitor complex
17. Investigation of the effects of sulfonylurea exposure on pancreatic beta cell metabolism
18. A Nuclear Magnetic Resonance-Based Demonstration of Substantial Oxidative L-Alanine Metabolism and L-Alanine-Enhanced Glucose Metabolism in a Clonal Pancreatic β-Cell Line: Metabolism of L-Alanine Is Important to the Regulation of Insulin Secretion
19. 13C NMR of cyanylated flavodoxin from megasphaera elsdenii and of thiocynate model compounds
20. Determination of the structure of tetrahedral transition state analogues bound at the active site of chymotrypsin using [super 18]O and [super 2]H isotope shifts in the [super 13]C NMR spectra of glyoxal inhibitors
21. A new lysine derived glyoxal inhibitor of trypsin, its properties and utilization for studying the stabilization of tetrahedral adducts by trypsin
22. Claisen-type addition of glycine to pyridoxal in water
23. A 13C-NMR study of azacryptand complexes
24. Studying enzyme mechanism by 13C nuclear magnetic resonance
25. 13C-NMR study of the inhibition of delta-chymotrypsin by a tripeptide-glyoxal inhibitor
26. Prolonged L-alanine exposure induces changes in metabolism, Ca2+ handling and desensitization of insulin secretion in clonal pancreatic ß-cells
27. A substrate-induced change in the stereospecificity of the serine-hydroxymethyltransferase-catalysed exchange of the alpha-protons of amino acids: evidence for a second catalytic site
28. Vinyl Sulfone-Based Peptidomimetics as Anti-Trypanosomal Agents: Design, Synthesis, Biological and Computational Evaluation
29. A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: metabolism of L-alanine is important to the regulation of insulin secretion.
30. Importance of Tetrahedral Intermediate Formation in the Catalytic Mechanism of the Serine Proteases Chymotrypsin and Subtilisin
31. Prolonged L-alanine exposure induces changes in metabolism, Ca2+ handling and desensitization of insulin secretion in clonal pancreatic β-cells
32. Determination of the Structure of Tetrahedral Transition State Analogues Bound at the Active Site of Chymotrypsin Using 18O and 2H Isotope Shifts in the 13C NMR Spectra of Glyoxal Inhibitors
33. NMR Study of the Inhibition of Pepsin by Glyoxal Inhibitors: Mechanism of Tetrahedral Intermediate Stabilization by the Aspartyl Proteases
34. The bioactive conformation of glucose‐dependent insulinotropic polypeptide by NMR and CD spectroscopy
35. 13C and 1H NMR Studies of Ionizations and Hydrogen Bonding in Chymotrypsin-Glyoxal Inhibitor Complexes
36. ID: 176 Inhibition of an Aspartyl Protease : Kinetic and NMR Studies on Pepsin
37. NMR and Alanine Scan Studies of Glucose-dependent Insulinotropic Polypeptide in Water
38. NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1–30)amide
39. Gliotoxins disrupt alanine metabolism and glutathione production in C6 glioma cells: a 13C NMR spectroscopic study
40. The stereospecificity and catalytic efficiency of the tryptophan synthase-catalysed exchange of the α-protons of amino acids
41. Biotransformation of halophenols using crude cell extracts of Pseudomonas putida F6
42. 13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and ?-glutamyl cycle activity in a clonal pancreatic beta-cell line
43. A 13C-NMR study of the inhibition of papain by a dipeptide-glyoxal inhibitor
44. 13C-NMR study of the inhibition of δ-chymotrypsin by a tripeptide-glyoxal inhibitor
45. Crystal structure of δ-chymotrypsin bound to a peptidyl chloromethyl ketone inhibitor
46. A 13C-NMR study of azacryptand complexes.
47. Using NMR as a Probe of Protein Structure and Function
48. pH-dependent spectroscopic changes associated with the hydroquinone of FMN in flavodoxins
49. 82 Quenching of β-lactoglobulin fluorescence by 2-nitro-5-thiobenzoic acid
50. 81 An attempt to cyanylate the the thiol group of Bovine Serum Albumin with 13C-enriched cyanide and to observe the thiocyanate carbon by 13C-NMR
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