1. [Evaluation of the rate of lipid peroxidation and antioxidant defense in blood during gynecological laparoscopic operations].
- Author
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Poliakova VA, Vinokurova EA, Suplotov SN, Zhuravleva TD, Karpova IA, Iaskevich NN, Malkhazova MT, and Karmatskikh TN
- Subjects
- Adult, Erythrocytes enzymology, Erythrocytes metabolism, Female, Glutathione Transferase blood, Humans, Leiomyoma pathology, Leiomyoma surgery, Malondialdehyde blood, Superoxide Dismutase blood, Uterine Neoplasms pathology, Uterine Neoplasms surgery, Uterus metabolism, Uterus pathology, Vitamin E blood, Antioxidants metabolism, Hysterectomy, Laparoscopy, Leiomyoma blood, Lipid Peroxidation, Uterine Neoplasms blood, Uterus surgery
- Abstract
The impact of gynecological operations on the rate of lipid peroxidation (LPO) and erythrocytic antioxidant defense (EAOD) was studied in women with uterine myoma. The higher rate of LPO and the decreased level of vitamin E were preoperatively found. A further increase in LPO activity and a reduction in vitamin E concentrations were observed 1-4 days after surgery. Recovery of the study parameters was seen on days 5-7 postoperatively. The enzyme glutathione-S-transferase was ascertained to play a pivotal role in the EAOD system.
- Published
- 2009