The purpose of this study was to determine the effect of the interaction of cow rumen trico compost and vegetable pesticides on the growth and production of tomato plants. Research entitled "Use of Cow Rumen Trico Compost and Betel Leaf Pesticides on Growth and Production of Tomato Plants (Lycopersicum esculentum Mill)". This research was carried out at the Experimental Garden of the Faculty of Agriculture, Riau Islamic University, Jalan Kaharuddin Nasution KM 11 No. 113 Marpoyan Stop, Air Cold Village, Bukit Raya District, Pekanbaru. The study was carried out for 4 months, from February to May 2021. The design used in the study was a factorial Completely Randomized Design (CRD) consisting of two factors. The first factor was cow rumen trico compost consisting of 4 levels, namely: 0, 187.50, 375.00 and 562.50 g/plant. The second factor is betel leaf pesticide consisting of 4 levels: 0, 50, 100 and 150 ml/l water. Observation parameters: plant height, flowering age, harvest age, number of fruit per plant, fruit weight per plant, fruit weight per fruit and number of remaining fruits. If the calculated F is greater than the F table, then it is continued with a further test of honest real difference (BNJ) at the level of 5%. The interaction of cow rumen trico compost and betel leaf pesticide affected all observation parameters. The best treatment dose of cow rumen compost was 562.50 g/plant and betel leaf pesticide concentration of 150 ml/l water. The main effect of cow rumen compost dose was on all observation parameters. The best treatment dose was 562.50 g/plant. The main effect of betel leaf pesticide concentration affects all observation parameters, where the best treatment is the concentration of 150 ml/l water. more...