217 results on '"Malinak, David"'
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2. Reactivators of butyrylcholinesterase inhibited by organophosphorus compounds
3. Strategies for enhanced bioavailability of oxime reactivators in the central nervous system
4. Cysteine conjugates of acetaminophen and p-aminophenol are potent inducers of cellular impairment in human proximal tubular kidney HK-2 cells
5. Halogenated monopyridinium oximes are less effective in reactivation of phosphylated cholinesterases than bisquaternary oximes
6. Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition
7. BODIPY-labelled acetylcholinesterase reactivators can be encapsulated into ferritin nanovehicles for enhanced bioavailability in the CNS
8. Toxicity, pharmacokinetics, and effectiveness of the ortho-chlorinated bispyridinium oxime, K870
9. Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents
10. Optimization of gradient reversed phase high performance liquid chromatography analysis of acetaminophen oxidation metabolites using linear and non-linear retention model
11. Implementation of an On-Site Food Prescription Project to Address Food Insecurity in Multiple Free Clinic Sites Serving an Adult Latinx Population.
12. Determination of K869, a Novel Oxime Reactivator of Acetylcholinesterase, in Rat Body Fluids and Tissues by Liquid-Chromatography Methods: Pharmacokinetic Study
13. Addressing food insecurity in San Diego by providing food to low-income patients with diabetes,educating health care providers, and increasing enrollment in CalFresh
14. Development of versatile and potent monoquaternary reactivators of acetylcholinesterase
15. The wide-spectrum antimicrobial effect of novel N-alkyl monoquaternary ammonium salts and their mixtures; the QSAR study against bacteria
16. A stereoselective approach in preparation of γ-lactam precursors for oxazolomycin’s synthesis
17. List of contributors
18. Novel cholinesterase reactivators
19. Rational design of novel TLR4 ligands by in silico screening and their functional and structural characterization in vitro
20. Oxime K203: a drug candidate for the treatment of tabun intoxication
21. Implementation of a food insecurity screening and referral program in student-run free clinics in San Diego, California
22. Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK).
23. Synthesis, antimicrobial evaluation and molecular modeling of 5-hydroxyisoquinolinium salt series; the effect of the hydroxyl moiety
24. STAT3 inhibitor Stattic and its analogues inhibit STAT3 phosphorylation and modulate cytokine secretion in senescent tumour cells
25. Ligand-based 3D QSAR analysis of reactivation potency of mono- and bis-pyridinium aldoximes toward VX-inhibited rat acetylcholinesterase
26. SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides
27. A diastereoselective C–C bond formation at C-5 of d-gulose. A convenient approach to (5S)-5-C-alkyl-β-l-lyxo-hexofuranoses
28. Implementation of an On-Site Food Prescription Project to Address Food Insecurity in Multiple Free Clinic Sites Serving an Adult Latinx Population
29. Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening
30. Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents
31. Modification of oxime nucleophiles for enhanced reactivation of cholinesterases
32. Charged pyridinium oximes with thiocarboxamide moiety are equally or less effective reactivators of organophosphate-inhibited cholinesterases compared to analogous carboxamides
33. The Effect of Chemical Structure of OEG Ligand Shells with Quaternary Ammonium Moiety on the Colloidal Stabilization, Cellular Uptake and Photothermal Stability of Gold Nanorods
34. Chapter 69 - Novel cholinesterase reactivators
35. The Effect of Chemical Structure of OEG Ligand Shells with Quaternary Ammonium Moiety on the Colloidal Stabilization, Cellular Uptake and Photothermal Stability of Gold Nanorods
36. Effects of Charged Oxime Reactivators on the HK-2 Cell Line in Renal Toxicity Screening
37. Design, synthesis, and in vitro evaluation of BP-1-102 analogs with modified hydrophobic fragments for STAT3 inhibition
38. Optimization of Gradient RP-HPLC Analysis of Acetaminophen Oxidation Metabolites Using Linear and Non-Linear Retention Model
39. Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates
40. Wide-Antimicrobial Spectrum of Picolinium Salts
41. Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators
42. Front Cover: Highly hydrophilic cationic gold nanorods stabilized by novel quaternary ammonium surfactant with negligible cytotoxicity (J. Biophotonics 12/2019)
43. Addressing food insecurity in San Diego by providing food to low-income patients with diabetes, educating health care providers, and increasing enrollment in CalFresh
44. Donepezil Derivatives Targeting Amyloid-β Cascade in Alzheimer's Disease
45. Highly hydrophilic cationic gold nanorods stabilized by novel quaternary ammonium surfactant with negligible cytotoxicity
46. Butyrylcholinesterase inhibited by nerve agents is efficiently reactivated with chlorinated pyridinium oximes
47. Oxime K203: a drug candidate for the treatment of tabun intoxication
48. Towards understanding the mechanism of action of antibacterial N-alkyl-3-hydroxypyridinium salts: Biological activities, molecular modeling and QSAR studies
49. Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents
50. A Review of the Synthesis of Quaternary Acetylcholinesterase Reactivators
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