138 results on '"Malerba, Francesca"'
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2. Selection and characterization of human scFvs targeting the SARS-CoV-2 nucleocapsid protein isolated from antibody libraries of COVID-19 patients
3. Lamotrigine rescues neuronal alterations and prevents seizure-induced memory decline in an Alzheimer's disease mouse model
4. Impaired synaptic plasticity in an animal model of autism exhibiting early hippocampal GABAergic-BDNF/TrkB signaling alterations
5. A p75 neurotrophin receptor‐sparing nerve growth factor protects retinal ganglion cells from neurodegeneration by targeting microglia.
6. A Quantitative Bioassay to Determine the Inhibitory Potency of NGF–TrkA Antagonists
7. Cerebrospinal fluid level of proNGF as potential diagnostic biomarker in patients with frontotemporal dementia
8. Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer’s Disease
9. Cladribine and ocrelizumab induce differential miRNA profiles in peripheral blood mononucleated cells from relapsing–remitting multiple sclerosis patients
10. A comparative analysis of the structural, functional and biological differences between Mouse and Human Nerve Growth Factor
11. The chemokine CXCL12 mediates the anti-amyloidogenic action of painless human nerve growth factor
12. The Cleavage-Specific Tau 12A12mAb Exerts an Anti-Amyloidogenic Action by Modulating the Endocytic and Bioenergetic Pathways in Alzheimer's Disease Mouse Model.
13. Nerve growth factor regulates axial rotation during early stages of chick embryo development
14. Direct intracellular selection and biochemical characterization of a recombinant anti-proNGF single chain antibody fragment
15. Targeting the Cation-Chloride Co-Transporter NKCC1 to Re-Establish GABAergic Inhibition and an Appropriate Excitatory/Inhibitory Balance in Selective Neuronal Circuits: A Novel Approach for the Treatment of Alzheimer’s Disease
16. Why Are We Scientists? Drawing Inspiration From Rita Levi-Montalcini
17. Tau Cleavage Contributes to Cognitive Dysfunction in Strepto-Zotocin-Induced Sporadic Alzheimer’s Disease (sAD) Mouse Model
18. proNGF Measurement in Cerebrospinal Fluid Samples of a Large Cohort of Living Patients With Alzheimer's Disease by a New Automated Immunoassay
19. sj-pdf-1-jbx-10.1177_24725552211000672 – Supplemental material for A Quantitative Bioassay to Determine the Inhibitory Potency of NGF–TrkA Antagonists
20. Nerve Growth Factor Neutralization Promotes Oligodendrogenesis by Increasing miR-219a-5p Levels
21. Passive immunotherapy for N-truncated tau ameliorates the cognitive deficits in two mouse Alzheimer’s disease models
22. The NGFR100WMutation Specifically Impairs Nociception without Affecting Cognitive Performance in a Mouse Model of Hereditary Sensory and Autonomic Neuropathy Type V
23. ProNGF Is a Cell-Type-Specific Mitogen for Adult Hippocampal and for Induced Neural Stem Cells
24. Mining clinical and laboratory data of neurodegenerative diseases by Machine Learning: transcriptomic biomarkers
25. A congenital pain insensitivity mutation in the nerve growth factor gene uncouples nociception from affective pain in heterozygous humans and mice
26. The NGFR100W Mutation Specifically Impairs Nociception without Affecting Cognitive Performance in a Mouse Model of Hereditary Sensory and Autonomic Neuropathy Type V.
27. ProNGF/NGF inbalance triggers neurodegeneration in transgenic mice
28. Intranasal administration of a painless human NGF reduces memory deficit and amyloid oligomers accumulation in APPxPS1 mice
29. Intranasal administration of an optimized human Nerve Growth Factor reduces memory deficits and amyloid oligomers accumulation in APPxPS1 mice
30. Over-expression of furin-resistant pro-NGF determines neurodegeneration in transgenic mice
31. The role of Nerve Growth Factor in development and in ALzheimer's disease
32. A new mechanism for Alzheimer neurodegeneration: functional antagonism between proNGF, mature NGF and their receptors
33. Involvement of NGF in early stages of chick embryo development
34. Identification of proNGF versus NGF expression fingerprinting in PC12 cells
35. The chemokine CXCL12 mediates the anti-amyloidogenic action of painless human nerve growth factor
36. Conformational Rigidity within Plasticity Promotes Differential Target Recognition of Nerve Growth Factor
37. NGF and proNGF Reciprocal Interference in Immunoassays: Open Questions, Criticalities, and Ways Forward
38. Intranasal but not intraparenchimal delivery of painless nerve growth factor rescues memory deficits in a mouse model of Alzheimer’s disease by targeting glial cells and reducing amyloid deposition through enhancement of neuronal SDF-1α
39. Functional Characterization of Human ProNGF and NGF Mutants: Identification of NGF P61SR100E as a “Painless” Lead Investigational Candidate for Therapeutic Applications
40. proNGF/NGF mixtures induce gene expression changes in PC12 cells that neither singly produces
41. Correction: Intranasal “painless” Human Nerve Growth Factors Slows Amyloid Neurodegeneration and Prevents Memory Deficits in App X PS1 Mice
42. Intranasal “painless” Human Nerve Growth Factors Slows Amyloid Neurodegeneration and Prevents Memory Deficits in App X PS1 Mice
43. Conformational Plasticity of proNGF
44. NGF and proNGF Regulate Functionally Distinct mRNAs in PC12 Cells: An Early Gene Expression Profiling
45. Intranasal delivery of therapeutic proteins for neurological diseases
46. Intrinsic structural disorder of mouse proNGF
47. The mechanism of addition of pyridoxal 5′-phosphate to Escherichia coli apo-serine hydroxymethyltransferase
48. Nerve Growth Factor Neutralization Promotes Oligodendrogenesis by Increasing miR-219a-5p Levels
49. A quantitative bioassay to determine the inhibitory potency of NGF-TrkA antagonists
50. proNGF Measurement in Cerebrospinal Fluid Samples of a Large Cohort of Living Patients With Alzheimer's Disease by a New Automated Immunoassay
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