Search

The growing penetration of IoT devices in power grids despite its benefits, raises cyber security concerns. In particular, load-altering attacks (LAAs) targetting high-wattage IoT-controllable load devices pose serious risks to grid stability and disrupt electricity markets. This paper provides a comprehensive review of LAAs, highlighting the threat model, analyzing its impact on transmission and distribution networks, and the electricity market dynamics. We also review the detection and localization schemes for LAAs that employ either model-based or data-driven approaches, with some hybrid methods combining the strengths of both. Additionally, mitigation techniques are examined, focusing on both preventive measures, designed to thwart attack execution, and reactive methods, which aim to optimize responses to ongoing attacks. We look into the application of each study and highlight potential streams for future research in this field.

This Paper investigate sequent calculi for certain weak subintuitionistic logics. We establish that weakening and contraction are height-preserving admissible for each of these calculi, and we provide a syntactic proof for the admissibility of the cut rule for most of these sequent calculi. We also demonstrate the equivalence of these calculi to their corresponding axiomatic systems, thereby confirming their soundness and completeness with respect to neighbourhood semantics., Comment: 36 pages

Procedural Content Generation (PCG) is defined as the automatic creation of game content using algorithms. PCG has a long history in both the game industry and the academic world. It can increase player engagement and ease the work of game designers. While recent advances in deep learning approaches in PCG have enabled researchers and practitioners to create more sophisticated content, it is the arrival of Large Language Models (LLMs) that truly disrupted the trajectory of PCG advancement. This survey explores the differences between various algorithms used for PCG, including search-based methods, machine learning-based methods, other frequently used methods (e.g., noise functions), and the newcomer, LLMs. We also provide a detailed discussion on combined methods. Furthermore, we compare these methods based on the type of content they generate and the publication dates of their respective papers. Finally, we identify gaps in the existing academic work and suggest possible directions for future research.

Quantum computing has the potential to revolutionize multiple fields by solving complex problems that can not be solved in reasonable time with current classical computers. Nevertheless, the development of quantum computers is still in its early stages and the available systems have still very limited resources. As such, currently, the most practical way to develop and test quantum algorithms is to use classical simulators of quantum computers. In addition, the development of new quantum computers and their components also depends on simulations. Given the characteristics of a quantum computer, their simulation is a very demanding application in terms of both computation and memory. As such, simulations do not scale well in current classical systems. Thus different optimization and approximation techniques need to be applied at different levels. This review provides an overview of the components of a quantum computer, the levels at which these components and the whole quantum computer can be simulated, and an in-depth analysis of different state-of-the-art acceleration approaches. Besides the optimizations that can be performed at the algorithmic level, this review presents the most promising hardware-aware optimizations and future directions that can be explored for improving the performance and scalability of the simulations.

The physicochemical properties of chemical compounds have great importance in several areas, including pharmaceuticals, environmental and separation science. Among these are physicochemical properties such as the octanol-water partition coefficient, which has been considered an important index pointing out lipophilicity and hydrophilicity. It affects drug absorption and membrane permeability. Following Lipinski's rule of five, logP was identified as one of the key determinants of the stability of chemical entities and, as such, needed state-of-the-art methods for measuring lipophilicity. This paper presents a deep-learning model, OWPCP, developed to compute logP using Morgan fingerprints and MACCS keys as input features. It uses the interconnection of such molecular representations with logP values extracted from 26,254 compounds. The dataset was prepared to contain a wide range of chemical structures with differing molecular weights and polar surface area. Hyperparameter optimization was conducted using the Keras Tuner alongside the Hyperband algorithm to enhance the performance. OWPCP demonstrated outstanding performance compared to current computational methods, achieving an MAE=0.247 on the test set and outperforming all previous DL models. Remarkably, while one of the most accurate recent models is based on experimental data on retention time to make predictions, OWPCP manages computing logP efficiently without depending on these factors, being, therefore, very useful during early-stage drug discovery. Our model outperforms the best model, which leverages Retention Time, and our model does not require any experimental data. Further validation of the model performance was done across different functional groups, and it showed very high accuracy, especially for compounds that contain aliphatic OH groups. The results have indicated that OWPCP provides a reliable prediction of logP., Comment: Preprint

Next-generation multiple access (NGMA) serves as an umbrella term for transmission schemes distinct from conventional orthogonal methods. A key candidate of NGMA, non-orthogonal multiple access (NOMA), emerges as a solution to enhance connectivity by allowing multiple users to share time, frequency, and space concurrently. However, NOMA faces challenges in implementation, particularly in canceling inter-user interference. In this paper, we discuss the principles behind NOMA and review conventional NOMA methods. Then, to address these challenges, we present asynchronous transmission and interference-aware modulation techniques, enabling decoding without successive interference cancellation. The goal is to design constellations that dynamically adapt to interference, minimizing bit error rates (BERs) and enhancing user throughput in the presence of inter-user, inter-carrier, and inter-cell interference. The traditional link between minimizing BER and increasing spectral efficiency is explored, with deep autoencoders for end-to-end communication emerging as a potential solution to improve BERs. Interference-aware modulation can revolutionize constellation design for non-orthogonal channels. Rate-splitting multiple access (RSMA) is another promising interference management technique in multi-user systems. In addition to addressing challenges in finite-alphabet NOMA, this paper offers new insights and provides an overview of code-domain NOMA, trellis-coded NOMA, and RSMA as key NGMA candidates. We also discuss the evolution of channel coding toward low-latency communication and examine modulation and coding schemes in 5G networks. Finally, we highlight future research directions, emphasizing their importance for realizing NOMA from concept to functional technology., Comment: Invited paper; to appear in the Proceedings of the IEEE

We study the problem of estimating a function in the presence of both speckle and additive noises. Although additive noise has been thoroughly explored in nonparametric estimation, speckle noise, prevalent in applications such as synthetic aperture radar, ultrasound imaging, and digital holography, has not received as much attention. Consequently, there is a lack of theoretical investigations into the fundamental limits of mitigating the speckle noise. This paper is the first step in filling this gap. Our focus is on investigating the minimax estimation error for estimating a $\beta$-H\"older continuous function and determining the rate of the minimax risk. Specifically, if $n$ represents the number of data points, $f$ denotes the underlying function to be estimated, and $\hat{\nu}_n$ is an estimate of $f$, then $\inf_{\hat{\nu}_n} \sup_f \mathbb{E}_f\| \hat{\nu}_n - f \|^2_2$ decays at the rate $n^{-\frac{2\beta}{2\beta+1}}$. Interestingly, this rate is identical to the one achieved for mitigating additive noise when the noise's variance is $\Theta(1)$. To validate the accuracy of our minimax upper bounds, we implement the minimax optimal algorithms on simulated data and employ Monte Carlo simulations to characterize their exact risk. Our simulations closely mirror the expected behaviors in decay rate as per our theory.

This paper presents and analyzes a reconfigurable intelligent surface (RIS)-based high-altitude platform (HAP) network. Stochastic geometry is used to model the arbitrary locations of the HAPs and RISs as a homogenous Poisson point process. Considering that the links between the HAPs, RISs, and users are $\kappa$--$\mu$ faded, the coverage and ergodic capacity of the proposed system are expressed. The analytically derived performance measures are verified through Monte Carlo simulations. Significant improvements in system performance and the impact of system parameters are demonstrated in the results. Thus, the proposed system concept can improve connectivity and data offloading in smart cities and dense urban environments.

Continuous-time series is essential for different modern application areas, e.g. healthcare, automobile, energy, finance, Internet of things (IoT) and other related areas. Different application needs to process as well as analyse a massive amount of data in time series structure in order to determine the data-driven result, for example, financial trend prediction, potential probability of the occurrence of a particular event occurrence identification, patient health record processing and so many more. However, modeling real-time data using a continuous-time series is challenging since the dynamical systems behind the data could be a differential equation. Several research works have tried to solve the challenges of modelling the continuous-time series using different neural network models and approaches for data processing and learning. The existing deep learning models are not free from challenges and limitations due to diversity among different attributes, behaviour, duration of steps, energy, and data sampling rate. This paper has described the general problem domain of time series and reviewed the challenges of modelling the continuous time series. We have presented a comparative analysis of recent developments in deep learning models and their contribution to solving different difficulties of modelling the continuous time series. We have also identified the limitations of the existing neural network model and open issues. The main goal of this review is to understand the recent trend of neural network models used in a different real-world application with continuous-time data.

Background: This study aimed to evaluate and compare the performance of classical machine learning models (CMLs) and large language models (LLMs) in predicting mortality associated with COVID-19 by utilizing a high-dimensional tabular dataset. Materials and Methods: We analyzed data from 9,134 COVID-19 patients collected across four hospitals. Seven CML models, including XGBoost and random forest (RF), were trained and evaluated. The structured data was converted into text for zero-shot classification by eight LLMs, including GPT-4 and Mistral-7b. Additionally, Mistral-7b was fine-tuned using the QLoRA approach to enhance its predictive capabilities. Results: Among the CML models, XGBoost and RF achieved the highest accuracy, with F1 scores of 0.87 for internal validation and 0.83 for external validation. In the LLM category, GPT-4 was the top performer with an F1 score of 0.43. Fine-tuning Mistral-7b significantly improved its recall from 1% to 79%, resulting in an F1 score of 0.74, which was stable during external validation. Conclusion: While LLMs show moderate performance in zero-shot classification, fine-tuning can significantly enhance their effectiveness, potentially aligning them closer to CML models. However, CMLs still outperform LLMs in high-dimensional tabular data tasks., Comment: Code is available at: https://github.com/mohammad-gh009/Large-Language-Models-vs-Classical-Machine-learning and https://github.com/Sdamirsa/Tehran_COVID_Cohort. The datasets are available from the corresponding author on reasonable request (sdamirsa@ymail.com)

We consider the jump-diffusion risky asset model and study its conditional prediction laws. Next, we explain the conditional least square hedging strategy and calculate its closed form for the jump-diffusion model, considering the Black-Scholes framework with interpretations related to investor priorities and transaction costs. We investigate the explicit form of this result for the particular case of the European call option under transaction costs and formulate recursive hedging strategies. Finally, we present a decision tree, table of values, and figures to support our results.

This study investigates the impact of significant health events on pharmaceutical stock performance, employing a comprehensive analysis incorporating macroeconomic and market indicators. Using Ordinary Least Squares (OLS) regression, we evaluate the effects of thirteen major health events since 2000, including the Anthrax attacks, SARS outbreak, H1N1 pandemic, and COVID-19 pandemic, on the pharmaceutical sector. The analysis covers different phases of each event beginning, peak, and ending to capture their temporal influence on stock prices. Our findings reveal distinct patterns in stock performance, driven by market reactions to the initial news, peak impact, and eventual resolution of these crises. We also examine scenarios with and without key macroeconomic (MA) and market (MI) indicators to isolate their contributions. This detailed examination provides valuable insights for investors, policymakers, and stakeholders in understanding the interplay between major health events and health market dynamics, guiding better decision-making during future health related disruptions., Comment: 17 pages, 5 figures, under review

Provenance, which traces data from its creation to manipulation, is crucial for ensuring data integrity, reliability, and trustworthiness. It is valuable for single-user applications, collaboration within organizations, and across organizations. Blockchain technology has become a popular choice for implementing provenance due to its distributed, transparent, and immutable nature. Numerous studies on blockchain designs are specifically dedicated to provenance, and specialize in this area. Our goal is to provide a new perspective in blockchain based provenance field by identifying the challenges faced and suggesting future research directions. In this paper, we categorize the problem statement into three main research questions to investigate key issues comprehensively and propose a new outlook on the use of blockchains. The first focuses on challenges in non-collaborative, single-source environments, the second examines implications in collaborative environments and different domains such as supply chain, scientific collaboration and digital forensic, and the last one analyzes communication and data exchange challenges between organizations using different blockchains. The interconnected nature of these research questions ensures a thorough exploration of provenance requirements, leading to more effective and secure systems. After analyzing the requirements of provenance in different environments, we provide future design considerations for provenance-based blockchains, including blockchain type, query mechanisms, provenance capture methods, and domain-specific considerations. We also discuss future work and possible extensions in this field.

A well-known result in dynamical systems asserts that any Cantor minimal system $(X,T)$ has a maximal rational equicontinuous factor $(Y,S)$ which is in fact an odometer, and realizes the rational subgroup of the $K_0$-group of $(X,T)$, that is, $\mathbb{Q}(K_0(X,T), 1) \cong K^0(Y,S)$. We introduce the notion of a maximal UHF subalgebra and use it to obtain the C*-algebraic alonog of this result. We say a UHF subalgebra $B$ of a unital C*-algebra $A$ is a maximal UHF subalgebra if it contains the unit of $A$ any other such C*-subalgebra embeds unitaly into $B$. We prove that if $K_0(A)$ is unperforated and has a certain $K_0$-lifting property, then $B$ exists and is unique up to isomorphism, in particular, all simple separable unital C*-algebras with tracial rank zero and all unital Kirchberg algebras whose $K_0$-groups are unperforated, have a maximal UHF subalgebra. Not every unital C*-algebra has a maximal UHF subalgebra, for instance, the unital universal free product $\mathrm{M}_2 \ast_{r} \mathrm{M}_3$. As an application, we give a C*-algebraic realization of the rational subgroup $\mathbb{Q}(G,u)$ of any dimension group $G$ with order unit $u$, that is, there is a simple unital AF algebra (and a unital Kirchberg algebra) $A$ with a maximal UHF subalgebra $B$ such that $(G,u)\cong (K_0(A), [1]_0)$ and and $\mathbb{Q}(G,u)\cong K_0(B)$., Comment: 27 pages

Electronic spectroscopy of zero-dimensional (0D) quantum systems, including point defects in solids, atomic states, and small molecules, is a critical tool for developing a fundamental understanding of these systems, with applications ranging from solid-state and molecular materials development to emerging technologies rooted in quantum information science. Toward this end, scanning tunneling spectroscopy (STS) has demonstrated atomic-scale sensitivity, but is not easily scalable for applications, whereas device-based approaches rely on embedding these systems within a solid-state tunnel junction (TJ) and are not generally applicable. Here we demonstrate an all-electrical readout mechanism for these quasi-0D states that is modular and general, dramatically expanding the phase space of accessible quantum systems and providing an approach that is amenable to scaling and integration with other solid-state quantum technologies. Our approach relies on the creation of high-quality tunnel junctions via the mechanical exfoliation and stacking of multi-layer graphene (MLG) and hexagonal boron nitride (hBN) to encapsulate the target quantum system (QS) in an MLG/hBN/QS/hBN/MLG heterostructure. This structure allows for electronic spectroscopy and readout of candidate quantum systems through a combination of Coulomb and spin-blockade, providing access to entire classes of quantum systems that have previously only been accessible via optical spectroscopy or magnetic resonance measurements of large ensembles, if at all.

We investigate the presence of antiferromagnetic fluctuations in the longitudinal and transversal spin susceptibilities of a square lattice. The inclusion of both first and second neighbour hopping terms, along with exchange coupling, induces anti-ferromagnetic fluctuations over a finite range of fillings in both longitudinal and transversal static spin susceptibilities. In the absence of on-site Hubbard interaction, we observe incommensurate antiferromagnetic fluctuations between the two Van Hove fillings. Beyond the second Van Hove singularity at $ n=1.03 $, commensurate antiferromagnetic fluctuations dominate in both longitudinal and transversal spin susceptibilities. When incorporating a finite Hubbard interaction strength, $ U $, we find that the commensurate anti-ferromagnetic fluctuations are preserved in both longitudinal and transversal dressed spin susceptibilities. However anti-ferromagnetic fluctuations vanish beyond a critical value of the Hubbard coupling strength, $ U_{c} $. Despite the exchange field can be induced by a ferromagnetic substrate, we do not observe any ferromagnetic fluctuations in the system., Comment: 9 pages, 9 figures

Pediatric central nervous system tumors are the leading cause of cancer-related deaths in children. The five-year survival rate for high-grade glioma in children is less than 20%. The development of new treatments is dependent upon multi-institutional collaborative clinical trials requiring reproducible and accurate centralized response assessment. We present the results of the BraTS-PEDs 2023 challenge, the first Brain Tumor Segmentation (BraTS) challenge focused on pediatric brain tumors. This challenge utilized data acquired from multiple international consortia dedicated to pediatric neuro-oncology and clinical trials. BraTS-PEDs 2023 aimed to evaluate volumetric segmentation algorithms for pediatric brain gliomas from magnetic resonance imaging using standardized quantitative performance evaluation metrics employed across the BraTS 2023 challenges. The top-performing AI approaches for pediatric tumor analysis included ensembles of nnU-Net and Swin UNETR, Auto3DSeg, or nnU-Net with a self-supervised framework. The BraTSPEDs 2023 challenge fostered collaboration between clinicians (neuro-oncologists, neuroradiologists) and AI/imaging scientists, promoting faster data sharing and the development of automated volumetric analysis techniques. These advancements could significantly benefit clinical trials and improve the care of children with brain tumors.

The integration of IoT-controllable devices in power systems (such as smart electric vehicle charging stations, heat pumps, etc.), despite their apparent benefits, raises novel cybersecurity concerns. These vulnerabilities in these devices can be leveraged to launch load-altering attacks (LAAs) that can potentially compromise power system safety. In this paper, we analyze the impact of LAAs on the voltage profile of distribution systems. We derive closed-form expressions to quantify the attack impact. Using the insights derived from this analysis, we propose a method to mitigate LAAs based on reconfiguring the distribution system as a reactive defense approach. We study optimal defense strategies using a non-cooperative sequential game theory approach that is robust to LAAs. The proposed solution takes the potential errors in the attack localization into account. Our results show that attacks launched on the deepest nodes in the distribution network result in the highest detrimental impact on the grid voltage profile. Furthermore, the proposed game-theoretic strategy successfully mitigates the effect of the attack while ensuring minimum system reconfiguration.

Evaporation of blood droplets and diluted blood samples is a topic of intensive research, as it is seen as a possible low-cost tool for diagnosis. So far, samples with volume fraction down to a few percents of Red Blood Cells (RBCs) have been studied, and those were reportedly dominated by a ``coffee-ring'' deposit. In this study, samples with lower volume fractions have been used in order to study the growth of the evaporative deposit from sessile droplets more in details. We observed that blood samples and salt solutions with less than 1\% volume fraction of RBCs are dominated by a central deposit. We characterized the growth process of this central deposit by evaporating elongated drops, and determined that it is consistent with the Kardar-Parisi-Zhang process in the presence of quenched disorder. Our results showed a sensitivity of this deposit size to the fibrinogen concentration and shape of the RBCs, meaning that this parameter could be used to develop a new and cost-effective clinical marker for inflammation and RBC deformation., Comment: 27 pages, 11 Figures

In digital forensics and various sectors like medicine and supply chain, blockchains play a crucial role in providing a secure and tamper-resistant system that meticulously records every detail, ensuring accountability. However, collaboration among different agencies, each with its own blockchains, creates challenges due to diverse protocols and a lack of interoperability, hindering seamless information sharing. Cross-chain technology has been introduced to address these challenges. Current research about blockchains in digital forensics, tends to focus on individual agencies, lacking a comprehensive approach to collaboration and the essential aspect of cross-chain functionality. This emphasizes the necessity for a framework capable of effectively addressing challenges in securely sharing case information, implementing access controls, and capturing provenance data across interconnected blockchains. Our solution, ForensiCross, is the first cross-chain solution specifically designed for digital forensics and provenance. It includes BridgeChain and features a unique communication protocol for cross-chain and multi-chain solutions. ForensiCross offers meticulous provenance capture and extraction methods, mathematical analysis to ensure reliability, scalability considerations for a distributed intermediary in collaborative blockchain contexts, and robust security measures against potential vulnerabilities and attacks. Analysis and evaluation results indicate that ForensiCross is secure and, despite a slight increase in communication time, outperforms in node count efficiency and has secure provenance extraction. As an all-encompassing solution, ForensiCross aims to simplify collaborative investigations by ensuring data integrity and traceability., Comment: This work has been submitted to the IEEE for possible publication

Video object segmentation approaches primarily rely on large-scale pixel-accurate human-annotated datasets for model development. In Dense Video Object Segmentation (DVOS) scenarios, each video frame encompasses hundreds of small, dense, and partially occluded objects. Accordingly, the labor-intensive manual annotation of even a single frame often takes hours, which hinders the development of DVOS for many applications. Furthermore, in videos with dense patterns, following a large number of objects that move in different directions poses additional challenges. To address these challenges, we proposed a semi-self-supervised spatiotemporal approach for DVOS utilizing a diffusion-based method through multi-task learning. Emulating real videos' optical flow and simulating their motion, we developed a methodology to synthesize computationally annotated videos that can be used for training DVOS models; The model performance was further improved by utilizing weakly labeled (computationally generated but imprecise) data. To demonstrate the utility and efficacy of the proposed approach, we developed DVOS models for wheat head segmentation of handheld and drone-captured videos, capturing wheat crops in fields of different locations across various growth stages, spanning from heading to maturity. Despite using only a few manually annotated video frames, the proposed approach yielded high-performing models, achieving a Dice score of 0.82 when tested on a drone-captured external test set. While we showed the efficacy of the proposed approach for wheat head segmentation, its application can be extended to other crops or DVOS in other domains, such as crowd analysis or microscopic image analysis.

Graphene has unique properties paving the way for groundbreaking future applications. Its large optical nonlinearity and ease of integration in devices notably makes it an ideal candidate to become a key component for all-optical switching and frequency conversion applications. In the terahertz (THz) region, various approaches have been independently demonstrated to optimize the nonlinear effects in graphene, addressing a critical limitation arising from the atomically thin interaction length. Here, we demonstrate sample architectures that combine strategies to enhance THz nonlinearities in graphene-based structures. We achieve this by increasing the interaction length through a multilayered design, controlling carrier density with an electrical gate, and modulating the THz field spatial distribution with a metallic metasurface substrate. Our study specifically investigates third harmonic generation (THG) using a table-top high-field THz source. We measure THG enhancement factors exceeding thirty and propose architectures capable of achieving a two-order-of-magnitude increase. These findings highlight the potential of engineered graphene-based samples in advancing THz frequency conversion technologies for signal processing and wireless communication applications., Comment: 13 pages (4 Figures) + 5 pages Supplementary Information (4 Figures)

Background and purpose: Deep Learning (DL) has been widely explored for Organs at Risk (OARs) segmentation; however, most studies have focused on a single modality, either CT or MRI, not both simultaneously. This study presents a high-performing DL pipeline for segmentation of 30 OARs from MRI and CT scans of Head and Neck (H&N) cancer patients. Materials and methods: Paired CT and MRI-T1 images from 42 H&N cancer patients alongside annotation for 30 OARs from the H&N OAR CT & MR segmentation challenge dataset were used to develop a segmentation pipeline. After cropping irrelevant regions, rigid followed by non-rigid registration of CT and MRI volumes was performed. Two versions of the CT volume, representing soft tissues and bone anatomy, were stacked with the MRI volume and used as input to an nnU-Net pipeline. Modality Dropout was used during the training to force the model to learn from the different modalities. Segmentation masks were predicted with the trained model for an independent set of 14 new patients. The mean Dice Score (DS) and Hausdorff Distance (HD) were calculated for each OAR across these patients to evaluate the pipeline. Results: This resulted in an overall mean DS and HD of 0.777 +- 0.118 and 3.455 +- 1.679, respectively, establishing the state-of-the-art (SOTA) for this challenge at the time of submission. Conclusion: The proposed pipeline achieved the best DS and HD among all participants of the H&N OAR CT and MR segmentation challenge and sets a new SOTA for automated segmentation of H&N OARs.

We describe the design and results from the BraTS 2023 Intracranial Meningioma Segmentation Challenge. The BraTS Meningioma Challenge differed from prior BraTS Glioma challenges in that it focused on meningiomas, which are typically benign extra-axial tumors with diverse radiologic and anatomical presentation and a propensity for multiplicity. Nine participating teams each developed deep-learning automated segmentation models using image data from the largest multi-institutional systematically expert annotated multilabel multi-sequence meningioma MRI dataset to date, which included 1000 training set cases, 141 validation set cases, and 283 hidden test set cases. Each case included T2, T2/FLAIR, T1, and T1Gd brain MRI sequences with associated tumor compartment labels delineating enhancing tumor, non-enhancing tumor, and surrounding non-enhancing T2/FLAIR hyperintensity. Participant automated segmentation models were evaluated and ranked based on a scoring system evaluating lesion-wise metrics including dice similarity coefficient (DSC) and 95% Hausdorff Distance. The top ranked team had a lesion-wise median dice similarity coefficient (DSC) of 0.976, 0.976, and 0.964 for enhancing tumor, tumor core, and whole tumor, respectively and a corresponding average DSC of 0.899, 0.904, and 0.871, respectively. These results serve as state-of-the-art benchmarks for future pre-operative meningioma automated segmentation algorithms. Additionally, we found that 1286 of 1424 cases (90.3%) had at least 1 compartment voxel abutting the edge of the skull-stripped image edge, which requires further investigation into optimal pre-processing face anonymization steps., Comment: 16 pages, 11 tables, 10 figures, MICCAI

Precision agriculture involves the application of advanced technologies to improve agricultural productivity, efficiency, and profitability while minimizing waste and environmental impact. Deep learning approaches enable automated decision-making for many visual tasks. However, in the agricultural domain, variability in growth stages and environmental conditions, such as weather and lighting, presents significant challenges to developing deep learning-based techniques that generalize across different conditions. The resource-intensive nature of creating extensive annotated datasets that capture these variabilities further hinders the widespread adoption of these approaches. To tackle these issues, we introduce a semi-self-supervised domain adaptation technique based on deep convolutional neural networks with a probabilistic diffusion process, requiring minimal manual data annotation. Using only three manually annotated images and a selection of video clips from wheat fields, we generated a large-scale computationally annotated dataset of image-mask pairs and a large dataset of unannotated images extracted from video frames. We developed a two-branch convolutional encoder-decoder model architecture that uses both synthesized image-mask pairs and unannotated images, enabling effective adaptation to real images. The proposed model achieved a Dice score of 80.7\% on an internal test dataset and a Dice score of 64.8\% on an external test set, composed of images from five countries and spanning 18 domains, indicating its potential to develop generalizable solutions that could encourage the wider adoption of advanced technologies in agriculture., Comment: 12

Sparse linear regression is one of the classical and extensively studied problems in high-dimensional statistics and compressed sensing. Despite the substantial body of literature dedicated to this problem, the precise determination of its minimax risk remains elusive. This paper aims to fill this gap by deriving asymptotically constant-sharp characterization for the minimax risk of sparse linear regression. More specifically, the paper focuses on scenarios where the sparsity level, denoted as k, satisfies the condition $(k \log p)/n {\to} 0$, with p and n representing the number of features and observations respectively. We establish that the minimax risk under isotropic Gaussian random design is asymptotically equal to $2{\sigma}^2k/n log(p/k)$, where ${\sigma}$ denotes the standard deviation of the noise. In addition to this result, we will summarize the existing results in the literature, and mention some of the fundamental problems that have still remained open.

Depthwise and pointwise convolutions have fewer parameters and perform fewer operations than standard convolutions. As a result, they have become increasingly used in various compact DNNs, including convolutional neural networks (CNNs) and vision transformers (ViTs). However, they have a lower compute-to-memory-access ratio than standard convolutions, making their memory accesses often the performance bottleneck. This paper explores fusing depthwise and pointwise convolutions to overcome the memory access bottleneck. The focus is on fusing these operators on GPUs. The prior art on GPU-based fusion suffers from one or more of the following: (1) fusing either a convolution with an element-wise or multiple non-convolutional operators, (2) not explicitly optimizing for memory accesses, (3) not supporting depthwise convolutions. This paper proposes Fused Convolutional Modules (FCMs), a set of novel fused depthwise and pointwise GPU kernels. FCMs significantly reduce pointwise and depthwise convolutions memory accesses, improving execution time and energy efficiency. To evaluate the trade-offs associated with fusion and determine which convolutions are beneficial to fuse and the optimal FCM parameters, we propose FusePlanner. FusePlanner consists of cost models to estimate the memory accesses of depthwise, pointwise, and FCM kernels given GPU characteristics. Our experiments on three GPUs using representative CNNs and ViTs demonstrate that FCMs save up to 83\% of the memory accesses and achieve speedups of up to 3.7x compared to cuDNN. Complete model implementations of various CNNs using our modules outperform TVMs' achieving speedups of up to 1.8x and saving up to two-thirds of the energy. FCM and FusePlanner implementations are open source: https://github.com/fqararyah/Fusing_DW_and_PW_on_GPUs.

Pediatric tumors of the central nervous system are the most common cause of cancer-related death in children. The five-year survival rate for high-grade gliomas in children is less than 20%. Due to their rarity, the diagnosis of these entities is often delayed, their treatment is mainly based on historic treatment concepts, and clinical trials require multi-institutional collaborations. Here we present the CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs challenge, focused on pediatric brain tumors with data acquired across multiple international consortia dedicated to pediatric neuro-oncology and clinical trials. The CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs challenge brings together clinicians and AI/imaging scientists to lead to faster development of automated segmentation techniques that could benefit clinical trials, and ultimately the care of children with brain tumors., Comment: arXiv admin note: substantial text overlap with arXiv:2305.17033

The $Q$-polynomial property is an algebraic property of distance-regular graphs, that was introduced by Delsarte in his study of coding theory. Many distance-regular graphs admit the $Q$-polynomial property. Only recently the $Q$-polynomial property has been generalized to graphs that are not necessarily distance-regular. In [ J. Combin. Theory Ser. A, 205:105872, 2024 ], it was shown that graphs arising from the Hasse diagrams of the so-called attenuated space posets are $Q$-polynomial. These posets could be viewed as $q$-analogs of the Hamming posets, which were not studied in [ J. Combin. Theory Ser. A, 205:105872, 2024 ]. The main goal of this paper is to fill this gap by showing that the graphs arising from the Hasse diagrams of the Hamming posets are $Q$-polynomial., Comment: arXiv admin note: text overlap with arXiv:2308.16679, arXiv:2305.08937

Phasor Measurement Units (PMUs) are used in the measurement, control and protection of power grids. However, deploying PMUs at every bus in a power system is prohibitively expensive, necessitating partial PMU placement that can ensure system observability with minimal units. One consequence of this economic approach is increased system vulnerability to False Data Injection Attacks (FDIAs). This paper proposes a zero-sum game-based approach to strategically place an additional PMU (following the initial optimal PMU deployment that ensures full observability) to bolster robustness against FDIAs by introducing redundancy in attack-susceptible areas. To compute the Nash equilibrium (NE) solution, we leverage a reinforcement learning algorithm that mitigates the need for complete knowledge of the opponent's actions. The proposed PMU deployment algorithm increases the detection rate of FDIA by 36% compared to benchmark algorithms.

Predicting stock price movements is a pivotal element of investment strategy, providing insights into potential trends and market volatility. This study specifically examines the predictive capacity of historical stock prices and technical indicators within the Global Industry Classification Standard (GICS) Information Technology Sector, focusing on companies established before 1980. We aim to identify patterns that precede significant, non-transient downturns - defined as declines exceeding 10% from peak values. Utilizing a combination of machine learning techniques, including multiple regression analysis, logistic regression, we analyze an enriched dataset comprising both macroeconomic indicators and market data. Our findings suggest that certain clusters of technical indicators, when combined with broader economic signals, offer predictive insights into forthcoming sector-specific downturns. This research not only enhances our understanding of the factors driving market dynamics in the tech sector but also provides portfolio managers and investors with a sophisticated tool for anticipating and mitigating potential losses from market downturns. Through a rigorous validation process, we demonstrate the robustness of our models, contributing to the field of financial analytics by offering a novel approach to predicting market downturns with significant implications for investment strategies and economic policy planning., Comment: 15 pages, 6 figures, under review by MDPI

Cardiovascular diseases are the leading cause of mortality globally, necessitating advancements in diagnostic techniques. This study explores the application of wavelet transformation for classifying electrocardiogram (ECG) signals to identify various cardiovascular conditions. Utilizing the MIT-BIH Arrhythmia Database, we employed both continuous and discrete wavelet transforms to decompose ECG signals into frequency sub-bands, from which we extracted eight statistical features per band. These features were then used to train and test various classifiers, including K-Nearest Neighbors and Support Vector Machines, among others. The classifiers demonstrated high efficacy, with some achieving an accuracy of up to 96% on test data, suggesting that wavelet-based feature extraction significantly enhances the prediction of cardiovascular abnormalities in ECG data. The findings advocate for further exploration of wavelet transforms in medical diagnostics to improve automation and accuracy in disease detection. Future work will focus on optimizing feature selection and classifier parameters to refine predictive performance further., Comment: 9 pages, 7 figures, under review by MDPI

The COVID-19 pandemic has presented unprecedented challenges worldwide, with its impact varying significantly across different geographic and socioeconomic contexts. This study employs a clustering analysis to examine the diversity of responses to the pandemic within the United States, aiming to provide nuanced insights into the effectiveness of various strategies. We utilize an unsupervised machine learning approach, specifically K-Means clustering, to analyze county-level data that includes variables such as infection rates, death rates, demographic profiles, and socio-economic factors. Our analysis identifies distinct clusters of counties based on their pandemic responses and outcomes, facilitating a detailed examination of "high-performing" and "lower-performing" groups. These classifications are informed by a combination of COVID-specific datasets and broader socio-economic data, allowing for a comprehensive understanding of the factors that contribute to differing levels of pandemic impact. The findings underscore the importance of tailored public health responses that consider local conditions and capabilities. Additionally, this study introduces an innovative visualization tool that aids in hypothesis testing and further research, enhancing the ability of policymakers and public health officials to deploy more effective and targeted interventions in future health crises., Comment: 12 pages, 7 figures, under review by MDPI

Thyroid cancer is an increasing global health concern that requires advanced diagnostic methods. The application of AI and radiomics to thyroid cancer diagnosis is examined in this review. A review of multiple databases was conducted in compliance with PRISMA guidelines until October 2023. A combination of keywords led to the discovery of an English academic publication on thyroid cancer and related subjects. 267 papers were returned from the original search after 109 duplicates were removed. Relevant studies were selected according to predetermined criteria after 124 articles were eliminated based on an examination of their abstract and title. After the comprehensive analysis, an additional six studies were excluded. Among the 28 included studies, radiomics analysis, which incorporates ultrasound (US) images, demonstrated its effectiveness in diagnosing thyroid cancer. Various results were noted, some of the studies presenting new strategies that outperformed the status quo. The literature has emphasized various challenges faced by AI models, including interpretability issues, dataset constraints, and operator dependence. The synthesized findings of the 28 included studies mentioned the need for standardization efforts and prospective multicenter studies to address these concerns. Furthermore, approaches to overcome these obstacles were identified, such as advances in explainable AI technology and personalized medicine techniques. The review focuses on how AI and radiomics could transform the diagnosis and treatment of thyroid cancer. Despite challenges, future research on multidisciplinary cooperation, clinical applicability validation, and algorithm improvement holds the potential to improve patient outcomes and diagnostic precision in the treatment of thyroid cancer., Comment: 50 pages, 8 figures, 1 table, 119 references

This report embarks on a mission to revolutionize clinical trial protocol development through the integration of advanced AI technologies. With a focus on leveraging the capabilities of generative AI, specifically GPT-4, this initiative aimed to streamline and enhance the efficiency and accuracy of clinical trial protocols. The methodology encompassed a detailed analysis and preparation of comprehensive drug and study level metadata, followed by the deployment of GPT-4 for automated protocol section generation. Results demonstrated a significant improvement in protocol authoring, highlighted by increases in efficiency, accuracy, and the customization of protocols to specific trial requirements. Challenges encountered during model selection and prompt engineering were systematically addressed, leading to refined methodologies that capitalized on the advanced text generation capabilities of GPT-4. This project not only showcases the practical applications and benefits of generative AI in clinical trial design but also sets a foundation for future innovations in the field., Comment: 29 pages, under review by IEEE Journal