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391 results on '"Malek-Hosseini, Seyed Ali"'

3. Post liver transplant complications of Budd-Chiari syndrome

Author

Asl, Ali Ansari, Lankarani, Kamran B., Nikeghbalian, Saman, Kazemi, Koroush, Shamsaieefar, Alireza, Alizade-Naini, Mahvash, Fattahi, Mohamad Reza, Taghavi, Seyed Alireza, Niknam, Ramin, Ejtehadi, Fardad, Dehghan, Masood, Sivandzadeh, Gholamreza, Ghahramani, Sulmaz, and Malek-Hosseini, Seyed Ali

Published
2021
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6. Allocation of liver grafts worldwide – Is there a best system?

Author

Lendoire, Javier, Imventarza, Oscar, Crawford, Michael, Andraus, Wellington, D'Albuquerque, Luiz Augusto Carneiro, Hernandez-Alejandro, Roberto, Dokus, M. Katherine, Tomiyama, Koji, Zheng, Shusen, Echeverri, Gabriel Jaime, Taimr, Pavel, Fronek, Jiri, de Rosner-van Rosmalen, Marieke, Vogelaar, Serge, Lesurtel, Mickael, Mabrut, Jean-Yves, Nagral, Sanjay, Kakaei, Farzad, Malek-Hosseini, Seyed Ali, Egawa, Hiroto, Contreras, Alan, Czerwinski, Jaroslaw, Danek, Teresa, Pinto-Marques, Hugo, Gautier, Sergey V., Monakhov, Artem, Melum, Espen, Ericzon, Bo-Göran, Kang, Koo Jeong, Kim, Myoung Soo, Sanchez-Velazquez, Patricia, Oberkofler, Christian Eugen, Müllhaupt, Beat, Linecker, Michael, Eshmuminov, Dilmurodjon, Grochola, Lukasz Filip, Song, Zhoulon, Kambakamba, Patryk, Chen, Chao-Long, Haberal, Mehmet, Yilmaz, Sezai, Rowe, Ian A.C., Kron, Philipp, Tschuor, Christoph, Ferrarese, Alberto, Kuemmerli, Christoph, Dutkowski, Philipp, Burra, Patrizia, and Clavien, Pierre-Alain

Published
2019
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7. Outcomes of liver transplantation for non-alcoholic steatohepatitis: A European Liver Transplant Registry study

Author

Haldar, Debashis, Kern, Barbara, Hodson, James, Armstrong, Matthew James, Adam, Rene, Berlakovich, Gabriela, Fritz, Josef, Feurstein, Benedikt, Popp, Wolfgang, Karam, Vincent, Muiesan, Paolo, O'Grady, John, Jamieson, Neville, Wigmore, Stephen J., Pirenne, Jacques, Malek-Hosseini, Seyed Ali, Hidalgo, Ernest, Tokat, Yaman, Paul, Andreas, Pratschke, Johann, Bartels, Michael, Trunecka, Pavel, Settmacher, Utz, Pinzani, Massimo, Duvoux, Christophe, Newsome, Philip Noel, and Schneeberger, Stefan

Published
2019
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23. Noninvasive Estimation of Hepatic Steatosis by Controlled Attenuation Parameter in Living Donor Liver Transplant

Author

Eshraghian, Ahad, primary, Fattahi, Mohammad Reza, additional, Mansourian, Mohsenreza, additional, Nikeghbalian, Saman, additional, Dehghani, Seyed Mohsen, additional, Taghavi, Alireza, additional, Kazemi, Kourosh, additional, Shamsaeefar, Alireza, additional, Geramizadeh, Bita, additional, and Malek-Hosseini, Seyed Ali, additional

Published
2022
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27. Immunosuppressive regimens on conversion of cytomegalovirus infection to disease in liver transplant recipients

Author

Rabbani, Amirhassan, Aliabbar, Shiva, Nikeghbalian, Saman, Malek-hosseini, Seyed Ali, and Baziboroun, M

Abstract

Background: Cytomegalovirus (CMV) disease is one of the most common infectious complications after liver transplantation. It is the cause of numerous morbidity and mortalities. Intensity of immunosuppression defined as overall immunosuppressive drug dosage seems to affect infectious complications. The main purpose of this study is to investigate the intensity of immunosuppression on conversion of CMV infection to disease in this population. Methods: In this cross-sectional study, we retrospectively evaluated and analyzed the data of all recipients who underwent orthotopic liver transplantation (OLT) between March 2014 and March 2016 and had positive serum PCR for CMV after transplantation in follow- up course. Of 134 recipients, only 66 adult liver transplant recipients were eligible to be studied. Multiple variables such as MELD score, cold ischemic time, warm ischemic time, operative data, immunosuppressive drugs and regimen, plasma CMV viral load, donor and recipient CMV IgG serostatus were recorded and analyzed. Results: of the 66 patients, 50 (76) had CMV infection and 16 (24) had disease. There was significant association between donor CMV IgG serostatus, extra corticosteroid pulse therapy, acute cellular rejection, serum tacrolimus level and conversion of CMV infection to CMV disease (P=0.005, 0.001, 0.031, 0.031). Conclusion: It seems that the intensity of immunosuppression has influence on conversion rate of CMV infection to disease in liver recipients.

Published
2022

29. Long-term outcome after living donor liver transplantation compared to donation after brain death in autoimmune liver diseases: Experience from the European Liver Transplant Registry

Author

Heinemann, Melina, Liwinski, Timur, Adam, Rene, Berenguer, Marina, Mirza, Darius, Malek-Hosseini, Seyed Ali, Heneghan, Michael A., Lodge, Peter, Pratschke, Johann, Boudjema, Karim, Paul, Andreas, Zieniewicz, Krzysztof, Fronek, Jiri, Mehrabi, Arianeb, Acarli, Koray, Tokat, Yaman, Coker, Ahmet, Yilmaz, Sezai, Karam, Vincent, Duvoux, Christophe, Lohse, Ansgar W., and Schramm, Christoph

Published
2022
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30. COVID-19 in Liver Transplant Patients: Report of 2 Cases and Review of the Literature

Author

Niknam, Ramin, Malek-Hosseini, Seyed Ali, Hashemieh, Seyed Saeid, and Dehghani, Masoud

Subjects
liver transplantation, immunosuppressant, education, coronavirus, COVID-19, Case Report, International Medical Case Reports Journal, management
Abstract

Ramin Niknam,1 Seyed Ali Malek-Hosseini,2 Seyed Saeid Hashemieh,1 Masoud Dehghani2 1Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; 2Shiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, IranCorrespondence: Masoud DehghaniShiraz Transplant Center, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, IranTel +989131415796Email dehghanimasood@yahoo.comAbstract: Coronavirus 2019 (COVID-19) is caused by a novel coronavirus. Although liver injury is common in patients with COVID-19, little is known about its clinical presentation and management in liver transplantation. This is the first report from Iran that presented two cases of liver transplantation with COVID-19, neither of which had pulmonary signs and symptoms, but after diagnostic imaging, both had lung involvement. We also reviewed some literature on the management of COVID-19 in liver transplant patients. In conclusion, our patients improved after starting hydroxychloroquine and continuing to take all immunosuppressive agents except mycophenolate based on the multidisciplinary team’s decision.Keywords: COVID-19, coronavirus, liver transplantation, immunosuppressant, management

Published
2020

31. Investigation of Integron-Associated Resistance Gene Cassettes in Urinary Isolates of Klebsiella pneumoniae in Yasuj, Southwestern Iran During 2015–16

Author

Jahanbin, Fariba, Marashifard, Masoud, Jamshidi, Sanaz, Zamanzadeh, Maryam, Dehshiri, Masumeh, Malek Hosseini, Seyed Ali Asghar, and Khoramrooz, Seyed Sajjad

Subjects
Klebsiella pneumoniae, Antibiotic resistance, Original Article, Iran, Integrons
Abstract

Background: Growing antibiotic resistance among urinary opportunistic pathogens such as Klebsiella pneumoniae (K. pneumonia) has created a worrisome condition in the treatment of the Urinary Tract Infections (UTIs) in recent years. Integrons play a significant role in the dissemination of antibiotic resistance genes. The present study was conducted to investigate class 1–3 integrons and the corresponding resistance gene cassettes in urinary K. pneumoniae isolates. Methods: In this study, from December 2015 to September 2016, a total of 196 K. pneumoniae isolates were collected from the patients with UTI referred to medical diagnostic laboratories in Yasouj, Southwestern Iran. Antibiotic susceptibility patterns of isolates were determined using 12 antibiotics by the disc diffusion method. Polymerase Chain Reaction (PCR) was used for detection of integron genes (intI1, intI2, and intI3). The variable regions of integrons were amplified by PCR and sequenced to identify the corresponding gene cassettes. Results: Thirty-nine different antibiotic resistance profiles were observed among K. pneumoniae isolates. Only 12.2% of K. pneumoniae isolates were found to harbor the intI1 gene. While 17 (60.7%) out of 28 Multidrug Resistance (MDR) K. pneumoniae isolates carried the intI1 gene, only 4.2% of non-MDR isolates harbored intI1 gene. Totally 7 different gene cassette arrays were found in the intI1 gene of K. pneumoniae isolates. The aadA1 was the most prominent gene cassette. Also, high frequency of dfrA containing gene cassettes was observed. Conclusion: Continuous monitoring and characterization of integrons and their associated gene cassettes could be helpful in controlling the rising rate of antibiotic resistance.

Published
2020

32. Pathology of pediatric liver tumors, a single center experience from south of Iran

Author

Geramizadeh Bita, Bahador Ali, Foroutan Hamid-Reza, Banani Abbas, Nikeghbalian Saman, and Malek-Hosseini Seyed-Ali

Subjects
Pathology, pediatric hepatic tumor, liver, RB1-214, Microbiology, QR1-502
Abstract

Background: Pediatric hepatic malignancies are rare, accounting for 1-4% of all solid childhood tumors. The histopathology of childhood hepatic tumors guides the treatment and prognosis, and is the cornerstone for precise diagnosis. Until now, there has been no documented study on pediatric liver tumor cases from this center; in this report, we show our experience about the common types of childhood hepatic tumors during five years (2002-2007) and compare them with other studies. Materials and Methods: During five years (2002-2007), all the hepatic tumors of childhood (under 18 year-old) from the pathology file of Namazi Hospital of Shiraz University of Medical Sciences are recorded. This includes both resected specimens and biopsies. All the slides were reviewed and the pathologic diagnosis was confirmed. Results: We detected 53 liver tumor cases in children (below 18 years of age). Among these tumors, 36 (67.9%) were malignant. Male to female ratio was 1.5 to 1. Hepatoblastoma was the most common liver tumor in this age group accounting for 22 patients (41.5%). The second most common primary tumor was hepatocellular carcinoma (HCC), with five patients. Another malignant tumor was embryonal sarcoma. Benign tumors included adenoma, mesenchymal hamartoma, vascular tumors, focal nodular hyperplasia, and inflammatory pseudo tumor. There were also seven metastatic tumors during these five years. Conclusions: The spectrum of hepatic tumors in children is different from that found in the older age group (adults) and also different in different populations.

Published
2010

35. Predictors of Death in the Liver Transplantation Adult Candidates: An Artificial Neural Networks and Support Vector Machine Hybrid-Based Cohort Study.

Author

Lankarani, Kamran Bagheri, Honarvar, Behnam, Pour, Farshad Shafi, Bagherpour, Morteza, Erjaee, Asma, Rouhezamin, Mohammad Reza, Khorrami, Mojdeh, Fard, Saeid Amiri Zadeh, Seifi, Vahid, Geramizadeh, Bita, Salahi, Heshmatollah, Nikeghbalian, Saman, Shamsaeefar, Alireza, Malek-hosseini, Seyed Ali, and Shirzadi, Saeedreza

Subjects
SUPPORT vector machines, LIVER transplantation, DECISION support systems, COHORT analysis, DECISION trees, ARTIFICIAL neural networks
Abstract

Background: Model for end-stage liver disease (MELD) is currently used for liver transplantation (LT) allocation, however, it is not a sufficient criterion. Objective: This current study aims to perform a hybrid neural network analysis of different data, make a decision tree and finally design a decision support system for improving LT prioritization. Material and Methods: In this cohort follow-up-based study, baseline characteristics of 1947 adult patients, who were candidates for LT in Shiraz Organ Transplant Center, Iran, were assessed and followed for two years and those who died before LT due to the end-stage liver disease were considered as dead cases, while others considered as alive cases. A well-organized checklist was filled for each patient. Analysis of the data was performed using artificial neural networks (ANN) and support vector machines (SVM). Finally, a decision tree was illustrated and a user friendly decision support system was designed to assist physicians in LT prioritization. Results: Between all MELD types, MELD-Na was a stronger determinant of LT candidates' survival. Both ANN and SVM showed that besides MELD-Na, age and ALP (alkaline phosphatase) are the most important factors, resulting in death in LT candidates. It was cleared that MELD-Na <23, age <53 and ALP <257 IU/L were the best predictors of survival in LT candidates. An applicable decision support system was designed in this study using the above three factors. Conclusion: Therefore, Meld-Na, age and ALP should be used for LT allocation. The presented decision support system in this study will be helpful in LT prioritization by LT allocators. [ABSTRACT FROM AUTHOR]

Published
2022
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36. Metabolic syndrome, hepatic fibrosis, and steatosis diagnosed by liver stiffness measurement and controlled attenuation parameter after liver transplantation: the impact on long-term survival.

Author

Eshraghian, Ahad, Fattahi, Mohammad Reza, Taghavi, Alireza, Shamsaeefar, Alireza, Mansoorian, Mohsenreza, Kazemi, Kourosh, Nikeghbalian, Saman, and Malek-Hosseini, Seyed Ali

Subjects
HEPATIC fibrosis, LIVER transplantation, FATTY liver, ETIOLOGY of diseases, FATTY degeneration, METABOLIC syndrome
Abstract

Liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) are used for diagnosis of liver fibrosis and steatosis. This study aimed to noninvasively evaluate hepatic steatosis and fibrosis in liver transplant recipients using CAP and LSM and the impact on survival of patients. In a prospective study, adult liver transplant recipients were included. CAP and LSM obtained during transient elastography (TE) were used for assessment of hepatic steatosis and fibrosis. Patients were followed during 4 years for mortality as the main outcome after liver transplantation. From 296 patients, 24.7% and 25% of liver transplant recipients had liver steatosis and fibrosis in CAP and LSM, respectively. In multivariable Cox regression analysis, etiology of liver disease (NASH versus non-NASH) (HR: 3.125; 95% CI: 1.594–6.134; p = 0.001), and post-transplant diabetes mellitus (PTDM) (HR: 2.617; 95% CI: 1.396–4.926; p = 0.003) were associated with hepatic steatosis after liver transplantation. In multivariable Cox regression analysis, liver fibrosis was an independent predictor of mortality after liver transplantation (HR: 4.926; 95%CI: 1.779–13.513; p = 0.002). CAP and LS measurement during TE are useful methods for diagnosis of hepatic steatosis and fibrosis in liver transplant recipients. LS measurement might predict long-term survival of patients. [ABSTRACT FROM AUTHOR]

Published
2022
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38. Evaluation of The Therapeutic Regimen in COVID-19 in Transplant Patients: Where Do Immunomodulatory and Antivirals Stand?

Author

Shafiekhani, Mojtaba, primary, Shahabinezhad, Farbod, additional, Niknam, Tahmoores, additional, Tara, Seyed Ahmad, additional, Haem, Elham, additional, Mardani, Parviz, additional, Zare, Zahra, additional, Jafarian, Sedigheh, additional, Jahromi, Khatereh Mirzad, additional, Arabsheybani, Sara, additional, Moeini, Yalda Sadat, additional, Jalali, Seyed Soroush, additional, Salimi, Maryam, additional, Shahriarirad, Reza, additional, and Malek-Hosseini, Seyed Ali, additional

Published
2021
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39. COVID-19 Versus Applied Infection Control Policies in a Major Transplant Center in Iran

Author

Shafiekhani, Mojtaba, primary, Niknam, Tahmooress, additional, Tara, Seied Ahmad, additional, Mardani, Parviz, additional, Jahromi, Khatereh Mirzad, additional, Jafarian, Sedigheh, additional, Arabsheybani, Sara, additional, Negahban, Halimeh, additional, Hamzehnejadi, Majid, additional, Zare, Zahra, additional, Ghalini, Khadijeh Ghaedi, additional, Ghasemnezhad, Ali, additional, Akbari, Mahmoud, additional, Shahriarirad, Reza, additional, and Malek‐Hosseini, Seyed Ali, additional

Published
2021
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50. Pure Uterine Lipoma and Focal Nodular Hyperplasia of the Liver: Concurrence of a Rare Tumor and Another Incidental Finding

Author

Anbardar, Mohammad Hossein, Soleimani, Neda, Malek-Hosseini, Seyed Ali, and Moradmand, Shirin

Subjects
stomatognathic diseases, Article Subject
Abstract

Background. Fatty uterine tumors, especially pure uterine lipoma, are very rare, but clinically and radiologically, they can mimic other primary benign and malignant uterine neoplasms. Case Report. A multipara 61-year-old postmenopausal woman presented with abnormal vaginal bleeding for 3 months. Assessment by ultrasound and magnetic resonance imaging (MRI) revealed a hyperechoic mass in the uterine corpus. Furthermore, during radiologic investigation, there was an incidental isoechoic mass in the left lobe of the liver. Pure uterine lipoma and hepatic focal nodular hyperplasia were diagnosed. Conclusion. Pure lipoma of the uterus, even though rare, has to be kept in the differential diagnosis of uterine neoplasms, especially in postmenopausal women. Till now, just a few concurrent tumors have been reported with pure uterine lipoma, and among them, FNH is the first extragenital tumor.

Published
2020
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